banner
Genes Phenotypes Help, News, Blog

Gene: Rgs7 MGI:1346089

Log in to follow
Not currently registered for phenotyping at IMPC

Phenotyping is currently not planned for a knockout strain of this gene.

Gene Summary

Name:
regulator of G protein signaling 7
Synonyms:
N/A

Order Alleles

IMPC Data Collections

  • No Body Weight Data
  • No Embryo Imaging Data
  • No Viability Data

IMPC Phenotype Summary

Significant
Not Significant
Not tested

View all our phenotype data below

Phenotypes

The IMPC applies a panel of phenotyping screens to characterise single-gene knockout mice by comparison to wild types. Click on the different tabs to visualise significant phenotypes identified by the IMPC, as well as all data that was measured.

lacZ Expression

Expression data not available

Associated Images

Images submitted by IMPC centres for a selection of procedures. Each set of images is available to view in our image comparator.

Phenotype associated images not available

Human diseases caused by Rgs7 mutations

The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.

Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.

No human diseases associated to this gene by orthology or annotation.

The table below shows human diseases predicted to be associated to Rgs7 by phenotypic similarity.

Disease Similarity of
phenotypes		 Matching phenotypes Source
Ataxia With Vitamin E Deficiency
Diabetes mellitus, Ataxia, Dysmetria, Dysdiadochokinesis, Gait disturbance, Mental deterioration,... ORPHA:96
Cortical Blindness-Intellectual Disability-Polydactyly Syndrome
Abnormality of visual evoked potentials, Short stature, Cachexia ORPHA:1389
Mitochondrial Dna Depletion Syndrome, Encephalomyopathic Form With Methylmalonic Aciduria
Abnormality of visual evoked potentials, Short stature, Cachexia, Ptosis ORPHA:1933
Neurodevelopmental Disorder With Midbrain And Hindbrain Malformations
Downslanted palpebral fissures, Abnormality of visual evoked potentials, Long eyelashes, Ptosis OMIM:617523
Peroxisomal Acyl-Coa Oxidase Deficiency
Abnormality of visual evoked potentials, Epicanthus, Failure to thrive ORPHA:2971
Cerebral Arteriopathy, Autosomal Dominant, With Subcortical Infarcts And Leukoencephalopathy, Type 1
Subcortical dementia, Dementia, Gait disturbance, Abnormality of visual evoked potentials, Memory... OMIM:125310
Oculocutaneous Albinism Type 1
Abnormality of visual evoked potentials, White eyelashes, White eyebrow ORPHA:352731
Ruvalcaba Syndrome
Delayed puberty, Abnormality of visual evoked potentials, Intrauterine growth retardation, Downsl... ORPHA:3121
Autosomal Dominant Optic Atrophy Plus Syndrome
Abnormality of visual evoked potentials, Bilateral ptosis ORPHA:1215
Xq12-Q13.3 Duplication Syndrome
Abnormality of visual evoked potentials, Epicanthus, Short stature ORPHA:314389
Pelizaeus-Merzbacher Disease
Abnormality of visual evoked potentials, Short stature, Failure to thrive in infancy, Cachexia ORPHA:702
Friedreich Ataxia
Diabetes mellitus, Ataxia, Limb ataxia, Gait ataxia, Abnormality of visual evoked potentials OMIM:229300
Developmental And Epileptic Encephalopathy 3
Abnormality of visual evoked potentials OMIM:609304
Autosomal Recessive Spastic Paraplegia Type 44
Abnormality of visual evoked potentials ORPHA:320401
Mepan Syndrome
Abnormality of visual evoked potentials, Failure to thrive ORPHA:508093
Canavan Disease
Abnormality of visual evoked potentials ORPHA:141
Stargardt Disease
Abnormality of visual evoked potentials ORPHA:827
Ichthyosis, Spastic Quadriplegia, And Impaired Intellectual Development
Growth delay, Abnormality of visual evoked potentials OMIM:614457
White-Sutton Syndrome
Short stature, Obesity, Upslanted palpebral fissure, Abnormality of visual evoked potentials, Int... OMIM:616364
Neurodegeneration With Brain Iron Accumulation 2A
Abnormality of visual evoked potentials OMIM:256600
Charcot-Marie-Tooth Disease, Type 4D
Abnormality of visual evoked potentials OMIM:601455
Late Infantile Neuronal Ceroid Lipofuscinosis
Abnormality of visual evoked potentials, Abnormal amplitude of flash visual evoked potentials ORPHA:168491
Micro Syndrome
Abnormality of visual evoked potentials, Intrauterine growth retardation, Short stature, Delayed ... ORPHA:2510
Cln5 Disease
Abnormality of visual evoked potentials ORPHA:228360
Neuropathy, Hereditary Motor And Sensory, Type Via, With Optic Atrophy
Abnormality of visual evoked potentials OMIM:601152
Infantile Krabbe Disease
Abnormality of visual evoked potentials, Failure to thrive, Cachexia ORPHA:206436
Cerebellar Atrophy, Visual Impairment, And Psychomotor Retardation
Abnormality of visual evoked potentials OMIM:616875
Mohr-Tranebjaerg Syndrome
Abnormality of visual evoked potentials ORPHA:52368
Late-Infantile/Juvenile Krabbe Disease
Abnormality of visual evoked potentials ORPHA:206443
Mff-Related Encephalopathy Due To Mitochondrial And Peroxisomal Fission Defect
Growth delay, Abnormality of visual evoked potentials ORPHA:485421
Infantile Neuroaxonal Dystrophy
Abnormality of visual evoked potentials ORPHA:35069
Achalasia-Addisonianism-Alacrima Syndrome
Abnormality of visual evoked potentials, Short stature OMIM:231550
Mogs-Cdg
Abnormality of visual evoked potentials, Long eyelashes, Short palpebral fissure ORPHA:79330
Global Developmental Delay-Visual Anomalies-Progressive Cerebellar Atrophy-Truncal Hypotonia Syndrome
Abnormality of visual evoked potentials ORPHA:480898
Hermansky-Pudlak Syndrome
Abnormality of visual evoked potentials, Long eyelashes, Weight loss ORPHA:79430
Oculocutaneous Albinism Type 1A
Abnormality of visual evoked potentials ORPHA:79431
Cockayne Syndrome B
Severe short stature, Small for gestational age, Postnatal growth retardation, Severe failure to ... OMIM:133540
Laminin Subunit Alpha 2-Related Congenital Muscular Dystrophy
Abnormality of visual evoked potentials, Decreased body weight ORPHA:258
Metachromatic Leukodystrophy, Late Infantile Form
Abnormality of visual evoked potentials ORPHA:309256
Metachromatic Leukodystrophy, Juvenile Form
Abnormality of visual evoked potentials ORPHA:309263
Cockayne Syndrome A
Short stature, Severe postnatal growth retardation, Abnormality of visual evoked potentials, Intr... OMIM:216400
Metachromatic Leukodystrophy, Adult Form
Abnormality of visual evoked potentials ORPHA:309271
Mitochondrial Dna Depletion Syndrome 4A (Alpers Type)
Abnormality of visual evoked potentials, Failure to thrive OMIM:203700
Cerebrotendinous Xanthomatosis
Abnormality of visual evoked potentials, Abnormal eyelid morphology ORPHA:909
Metachromatic Leukodystrophy
Abnormality of visual evoked potentials ORPHA:512
Autosomal Recessive Malignant Osteopetrosis
Growth delay, Abnormality of visual evoked potentials ORPHA:667

Histopathology

Summary table of phenotypes displayed during the Histopathology procedure which are considered significant. Full histopathology data table, including submitted images, can be accessed by clicking any row in this table.

There is no histopathology data for Rgs7

IMPC related publications

The table below lists publications which used either products generated by the IMPC or data produced by the phenotyping efforts of the IMPC. These publications have also been associated to Rgs7.

No publications found that use IMPC mice or data for Rgs7.

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.

MGI Allele Allele Type Produced
Rgs7tm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells

The IMPC Newsletter

Get highlights of the most important data releases, news and events, delivered straight to your email inbox

Subscribe to newsletter