Gene: Myh1

Name myosin, heavy polypeptide 1, skeletal muscle, adult

Synonyms
  • MYHC-IIX
  • Myhsf2
  • A530084A17Rik
  • IId/x
  • MyHC-IId/x
  • IId
  • myosin heavy chain 2X
  • Myhs-f
  • Myhs-f2

Status ES CellsMice
tm1a
Mice
tm1b
phenotype data available

Links MGI:1339711   Ensembl Gene   Ensembl Orthologs

Viability Homozygous - Viable

Phenotype associations for Myh1

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Myh1 data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
abnormal bone structure Myh1tm1b(KOMP)Wtsi HOM Female Male postnatal 0.0
decreased bone mineral density Myh1tm1b(KOMP)Wtsi HOM Female Male postnatal 1.16E-43
decreased startle reflex Myh1tm1b(KOMP)Wtsi HOM Female Male postnatal 1.38E-22
abnormal sleep behavior Myh1tm1b(KOMP)Wtsi HOM Female Male postnatal 4.05E-22
decreased bone mineral content Myh1tm1b(KOMP)Wtsi HOM Female postnatal 1.66E-16
decreased grip strength Myh1tm1b(KOMP)Wtsi HOM Female Male postnatal 1.43E-15
abnormal behavioral response to light Myh1tm1b(KOMP)Wtsi HOM Female Male postnatal 9.69E-13
absent startle reflex Myh1tm1b(KOMP)Wtsi HOM Female Male postnatal 1.33E-11
decreased anxiety-related response Myh1tm1b(KOMP)Wtsi HOM Female Male postnatal 1.01E-10
decreased leukocyte cell number Myh1tm1b(KOMP)Wtsi HOM Female Male postnatal 2.55E-10
increased hematocrit Myh1tm1b(KOMP)Wtsi HOM Female Male postnatal 2.87E-10
increased erythrocyte cell number Myh1tm1b(KOMP)Wtsi HOM Female Male postnatal 8.24E-9
abnormal vocalization Myh1tm1b(KOMP)Wtsi HOM Female Male postnatal 2.8E-8
decreased urine creatinine level Myh1tm1b(KOMP)Wtsi HOM Female Male postnatal 1.7E-7
decreased exploration in new environment Myh1tm1b(KOMP)Wtsi HOM Female Male postnatal 2.39E-7
increased hemoglobin content Myh1tm1b(KOMP)Wtsi HOM Female Male postnatal 1.23E-6
convulsive seizures Myh1tm1b(KOMP)Wtsi HOM Male postnatal 2.67E-6
increased total body fat amount Myh1tm1b(KOMP)Wtsi HOM Female Male postnatal 1.33E-5
decreased lean body mass Myh1tm1b(KOMP)Wtsi HOM Female Male postnatal 1.84E-5
decreased prepulse inhibition Myh1tm1b(KOMP)Wtsi HOM Female Male postnatal 2.25E-5
abnormal motor learning Myh1tm1b(KOMP)Wtsi HOM Female Male postnatal 2.9E-5
decreased body length Myh1tm1b(KOMP)Wtsi HOM Female postnatal 3.09E-5
increased body length Myh1tm1b(KOMP)Wtsi HOM Male postnatal 3.09E-5
increased or absent threshold for auditory brainstem response Myh1tm1b(KOMP)Wtsi HOM Female Male postnatal 4.22E-5

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
No expression data was found for this adult tab
No expression image was found for this adult tab

 Expression    No Expression    No Tissue Available    Ambiguous  

Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 2 (5/413)
Dorsal root ganglion 2 No Data
Ear 2
Embryo 2
Eye 2
Foot 2
Forebrain 2
Forelimb 2
Fronto-nasal process 2
Hand 2
Head 2 (4/413)
Heart 2
Hindbrain 2 (5/413)
Hindlimb 2
Liver 2
Lung 2
Mandibular process 2
Maxillary process 2
Midbrain 2
Nose 2 No Data
Oral cavity 2
Skin 2
Spinal cord 2 No Data
Tail 2
Tail somite 2


Associated Images

Associated Images
  • X-ray: XRay Images Skull Dorso Ventral Orientation
    11 Images
  • X-ray: XRay Images Dorso Ventral
    11 Images
  • X-ray: XRay Images Lateral Orientation
    11 Images
  • X-ray: XRay Images Forepaw
    11 Images
  • X-ray: XRay Images Skull Lateral Orientation
    11 Images

Disease Models

No associations by disease annotation and gene orthology found.

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse
Myh1tm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene
Myh1tm1b(KOMP)Wtsi Reporter-tagged deletion allele (post-Cre)
Vector
Gene
Myh1tm2a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene