Gene: Myh1

Order

Name myosin, heavy polypeptide 1, skeletal muscle, adult

Synonyms
  • Myhsf2
  • IId/x
  • MyHC-IId/x
  • A530084A17Rik
  • IId
  • Myhs-f2
  • Myhs-f
  • myosin heavy chain 2X
  • MYHC-IIX

Status ES CellsMice
tm1a
Mice
tm1b
phenotype data available

Links MGI:1339711    Ensembl Gene    Ensembl Orthologs    My Genes   

Viability Homozygous - Viable

Phenotype associations for Myh1

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Myh1 data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
abnormal bone structure Myh1tm1b(KOMP)Wtsi HOM Female Male postnatal 0.0
decreased bone mineral content Myh1tm1b(KOMP)Wtsi HOM Female Male postnatal 0.0
decreased bone mineral density Myh1tm1b(KOMP)Wtsi HOM Female Male postnatal 0.0
decreased lean body mass Myh1tm1b(KOMP)Wtsi HOM Female Male postnatal 0.0
decreased startle reflex Myh1tm1b(KOMP)Wtsi HOM Female Male postnatal 2.22E-22
abnormal sleep behavior Myh1tm1b(KOMP)Wtsi HOM Female Male postnatal 4.05E-22
decreased grip strength Myh1tm1b(KOMP)Wtsi HOM Female Male postnatal 1.09E-20
absent startle reflex Myh1tm1b(KOMP)Wtsi HOM Female Male postnatal 7.96E-14
abnormal behavioral response to light Myh1tm1b(KOMP)Wtsi HOM Female Male postnatal 6.08E-12
decreased anxiety-related response Myh1tm1b(KOMP)Wtsi HOM Female Male postnatal 1.22E-10
abnormal vocalization Myh1tm1b(KOMP)Wtsi HOM Female Male postnatal 1.72E-8
decreased body length Myh1tm1b(KOMP)Wtsi HOM Female Male postnatal 2.92E-8
decreased total body fat amount Myh1tm1b(KOMP)Wtsi HOM Male postnatal 3.98E-8
decreased urine creatinine level Myh1tm1b(KOMP)Wtsi HOM Female Male postnatal 1.7E-7
decreased exploration in new environment Myh1tm1b(KOMP)Wtsi HOM Female Male postnatal 2.64E-7
convulsive seizures Myh1tm1b(KOMP)Wtsi HOM Male postnatal 2.67E-6
decreased leukocyte cell number Myh1tm1b(KOMP)Wtsi HOM Female Male postnatal 4.26E-6
decreased prepulse inhibition Myh1tm1b(KOMP)Wtsi HOM Female Male postnatal 6.98E-6
increased hematocrit Myh1tm1b(KOMP)Wtsi HOM Female Male postnatal 2.06E-5
increased erythrocyte cell number Myh1tm1b(KOMP)Wtsi HOM Female Male postnatal 2.08E-5
abnormal motor learning Myh1tm1b(KOMP)Wtsi HOM Female Male postnatal 2.9E-5
increased or absent threshold for auditory brainstem response Myh1tm1b(KOMP)Wtsi HOM Female Male postnatal 8.77E-5

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No (5/393)
Aorta 2 No (1/562)
Brain 2 No (6/562)
Brainstem 2 No (4/562)
Brown adipose tissue 2 No
Cartilage tissue 2 No (1/562)
Cerebellum 2 No (4/562)
Cerebral cortex 2 No (5/562)
Epididymis 2 No (4/106)
Esophagus 2 No (2/393) (2/2)
Eye 2 No (1/562)
Heart 2 No (3/562)
Hippocampus 2 No (5/562)
Hypothalamus 2 No (4/562)
Kidney 2 No (20/562) (2/2)
Large intestine 2 No (12/562) (2/2)
Liver 2 No
Lower urinary tract 2 No (3/562)
Lung 2 No (3/562)
Lymph node 2 No (1/562)
Mammary gland 2 No
Midbrain 2 No
Olfactory lobe 2 No (4/393)
Ovary 2 No (1/562) (1/2)
Oviduct 2 No (2/562)
Pancreas 2 No (6/562)
Peripheral nervous system 2 No (3/562)
Peyer's patch 2 No (1/393)
Pituitary gland 2 No (1/562)
Prostate gland 2 No (5/562)
Skeletal muscle 2 No (2/2)
Skin 2 No (1/562)
Small intestine 2 No (11/562) (2/2)
Spinal cord 2 No (3/562)
Spleen 2 No (4/562)
Stomach 2 No (9/562)
Striatum 2 No (4/562)
Submandibular gland 2 No (1/104)
Testis 2 No (4/562) (1/2)
Thalamus 2 No
Thymus 2 No
Thyroid gland 2 No (16/562)
Trachea 2 No (3/562)
Urinary bladder 2 No
Uterus 2 No (2/562)
Vascular system 2 No (1/393)
Vesicular gland 2 No
White adipose tissue 2 No
Expression in Anatomogram

Tissues/organs lacZ+ expression

    postnatal mouse digestive system reproductive system musculoskeletal system trunk urinary system
No expression image was found for this adult tab

 Expression    No Expression    No Tissue Available    Ambiguous  

Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 2 (6/482)
Dorsal root ganglion 2 (1/45)
Ear 2 (1/482)
Embryo 2 (1/482)
Eye 2 (1/482)
Foot 2 (1/482)
Forebrain 2 (1/482)
Forelimb 2 (1/482)
Fronto-nasal process 2 (1/46)
Hand 2 (1/482)
Head 2 (5/482)
Heart 2 (1/482)
Hindbrain 2 (6/482)
Hindlimb 2 (1/482)
Liver 2 (1/482)
Lung 2 (1/482)
Mandibular process 2 (1/482)
Maxillary process 2 (1/482)
Midbrain 2 (1/482)
Nose 2 (1/47)
Oral cavity 2 (1/482)
Skin 2 (1/482)
Spinal cord 2 (1/46)
Tail 2 (1/482)
Tail somite 2 (1/482)


Associated Images

Associated Images
  • X-ray: XRay Images Skull Lateral Orientation
    14 Images
  • X-ray: XRay Images Skull Dorso Ventral Orientation
    14 Images
  • X-ray: XRay Images Dorso Ventral
    14 Images
  • Sleep Wake: Wake state (bmp file)
    10 Images
  • Electroretinography 2: Rod and cone PDF
    3 Images
  • X-ray: XRay Images Forepaw
    14 Images
  • X-ray: XRay Images Lateral Orientation
    14 Images
  • Eye Morphology: Images Slit Lamp
    1 Images

Disease Models

No associations by disease annotation and gene orthology found.

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Myh1tm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene
Myh1tm1b(KOMP)Wtsi Reporter-tagged deletion allele (post-Cre)
Vector
Gene
Myh1tm2a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene