Gene: Aspm

Name abnormal spindle microtubule assembly

Synonyms
  • Sha1
  • MCPH5
  • Calmbp1
  • D330028K02Rik
  • Aspm

Status ES CellsMice
tm1a
phenotype data available

Links MGI:1334448   Ensembl Gene   Ensembl Orthologs

Viability Homozygous - Viable

Phenotype associations for Aspm

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Aspm data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
increased circulating cholesterol level Aspmtm1a(KOMP)Wtsi HOM Female Male postnatal 2.59E-7
thrombocytopenia Aspmtm1a(KOMP)Wtsi HOM Female Male postnatal 1.07E-6
increased total body fat amount Aspmtm1a(KOMP)Wtsi HOM Female Male postnatal 1.43E-6
increased circulating HDL cholesterol level Aspmtm1a(KOMP)Wtsi HOM Female Male postnatal 1.73E-6

Download data as: TSV XLS



Expression

Expression data not available

Associated Images

Associated Images
  • Brain Histopathology: Cerebellar Section
    3 Images
  • Brain Histopathology: Striatal Section
    3 Images
  • Brain Histopathology: Hippocampal section
    3 Images
  • X-ray: XRay Images Dorso Ventral
    39 Images
  • X-ray: XRay Images Skull Dorso Ventral Orientation
    13 Images
  • X-ray: XRay Images Forepaw
    12 Images
  • X-ray: XRay Images Skull Lateral Orientation
    13 Images
  • X-ray: XRay Images Lateral Orientation
    27 Images
Legacy Phenotype Associated Images
Xray (105)
  • Aspmtm1a(KOMP)Wtsi
    HOM, Female, WTSI
  • Aspmtm1a(KOMP)Wtsi
    HOM, Female, WTSI
  • Aspmtm1a(KOMP)Wtsi
    HOM, Female, WTSI
  • Aspmtm1a(KOMP)Wtsi
    HOM, Female, WTSI
  • Aspmtm1a(KOMP)Wtsi
    HOM, Female, WTSI

show all 105 images

Brain Histopathology (15)
  • Aspmtm1a(KOMP)Wtsi
    CORPUS CALLOSUM, decreased corpus callosum size, HOM, Male, WTSI
  • Aspmtm1a(KOMP)Wtsi
    HOM, Male, WTSI
  • Aspmtm1a(KOMP)Wtsi
    decreased retrosplenial granular cortex size, HOM, Male, WTSI
  • Aspmtm1a(KOMP)Wtsi
    WT, Male, WTSI
  • Aspmtm1a(KOMP)Wtsi
    HOM, Male, WTSI

show all 15 images

Skin Histopathology (1)
  • Aspmtm1a(KOMP)Wtsi
    HOM, Female, WTSI

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse
Aspmtm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene