Not currently registered for phenotyping at IMPC
Phenotyping is currently not planned for a knockout strain of this gene.
Gene Summary
IMPC Data Collections
- No Body Weight Data
- No Embryo Imaging Data
- No Viability Data
Phenotyping is currently not planned for a knockout strain of this gene.
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
The table below shows human diseases predicted to be associated to Cyth2 by phenotypic similarity.
The table below lists publications which used either products generated by the IMPC or data produced by the phenotyping efforts of the IMPC. These publications have also been associated to Cyth2.
There are 3 publications which use IMPC produced mice or data.
Title | Journal | IMPC Allele | PubMed ID |
---|---|---|---|
Cytohesin-2 mediates group I metabotropic glutamate receptor-dependent mechanical allodynia through the activation of ADP ribosylation factor 6 in the spinal cord. | Neurobiology of disease (August 2021) | Cyth2tm1c(EUCOMM)Wtsi | 34390832 |
Deletion of Arno Reduces Eosinophilic Inflammation and Interleukin-5 Expression in a Murine Model of Rhinitis. | Ear, nose, & throat journal (January 2021) | Cyth2tm1c(EUCOMM)Wtsi Cyth2tm1a(EUCOMM)Wtsi Cyth2tm1d(EUCOMM)Wtsi | 33393815 |
Arf6 guanine-nucleotide exchange factor cytohesin-2 regulates myelination in nerves. | Biochemical and biophysical research communications (March 2015) | Cyth2tm1c(EUCOMM)Wtsi Cyth2tm1a(EUCOMM)Wtsi | 25824033 |
All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.
MGI Allele | Allele Type | Produced |
---|---|---|
Cyth2tm1e(EUCOMM)Wtsi | Targeted, non-conditional allele | ES Cells |
Cyth2tm1a(EUCOMM)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | Targeting vectors, ES Cells |
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