Gene: Lhx6

Order

Name LIM homeobox protein 6

Status ES CellsMice
tm1a
Mice
tm1b
phenotype data available

Links MGI:1306803    Ensembl Gene    Ensembl Orthologs    My Genes   

Viability Homozygous - Subviable

Phenotype associations for Lhx6

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Lhx6 data for that phenotype.

Embryo Data: 3D Embryo Imaging
Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
preweaning lethality, incomplete penetrance Lhx6tm1b(KOMP)Wtsi HOM Female Male n/a 0.0
abnormal behavior Lhx6tm1b(KOMP)Wtsi HET Female Male postnatal 1.88E-6
hypoactivity Lhx6tm1b(KOMP)Wtsi HET Female Male postnatal 1.99E-6

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 1 No (2/415)
Aorta 1 No
Blood 1 No
Bone marrow 1 No
Brain 1 No
Brainstem 1 No
Brown adipose tissue 1 No
Cartilage tissue 1 No
Cecum 1 No (12/383)
Cerebellum 1 No
Cerebral cortex 1 No
Chest bone 1 No
Colon 1 No (12/127)
Diaphragm 1 No
Duodenum 1 No (2/127)
Epididymis 1 No (18/134) (1/1)
Esophagus 1 No (7/415)
Eye 1 No
Gall bladder 1 No
Gonadal fat pad 1 No
Harderian gland 1 No
Heart 1 No
Hindlimb 1 No
Hippocampus 1 No
Hypothalamus 1 No
Ileum 1 No (14/127) (1/1)
Jejunum 1 No (6/127)
Kidney 1 No (18/584)
Large intestine 1 No (10/584)
Liver 1 No
Lower urinary tract 1 No
Lung 1 No
Lymph node 1 No
Mammary gland 1 No
Mesenteric lymph node 1 No
Mesenteric adipose tissue 1 No (1/1)
Midbrain 1 No (1/1)
Olfactory lobe 1 No
Ovary 1 No (1/584)
Oviduct 1 No
Pancreas 1 No (5/584)
Parathyroid gland 1 No
Parotid gland 1 No
Penis 1 No
Peripheral nervous system 1 No
Peyer's patch 1 No
Pituitary gland 1 No
Prostate gland 1 No (12/584)
Quadriceps 1 No (1/1)
Sciatic nerve 1 No
Skeletal muscle 1 No
Skin 1 No
Small intestine 1 No (9/584)
Spinal cord 1 No
Spleen 1 No (2/584)
Stomach 1 No (12/584)
Stomach pyloric region 1 No
Striatum 1 No
Sublingual gland 1 No
Submandibular gland 1 No (2/132)
Testis 1 No (2/584) (1/1)
Thymus 1 No
Thyroid gland 1 No (15/584)
Tongue 1 No (5/127) (1/1)
Trachea 1 No (1/1)
Trigeminal V nerve 1 No
Urinary bladder 1 No
Uterus 1 No
Vagina 1 No
Vas deferens 1 No (15/388) (1/1)
Vascular system 1 No
Vesicular gland 1 No
White adipose tissue 1 No
Expression in Anatomogram

Tissues/organs lacZ+ expression

    postnatal mouse respiratory system digestive system nervous system set of connective tissues sensory organ reproductive system adipose tissue musculoskeletal system trunk
No expression image was found for this adult tab

 Expression    No Expression    No Tissue Available    Ambiguous  

Anatomy #HET Specimens WT Expr Mutant Expr Images
Axial skeleton 2 (1/51)
Brain 3 (6/485)
Central nervous system ganglion 2 (1/51) (2/2)
Ear 3 (1/485) (2/5)
Embryo 3 (1/485) (2/5)
Eye 3 (1/485) (2/5)
Foot 3 (1/485)
Forebrain 3 (1/485)
Forelimb 3 (1/485)
Gut 2 (1/50)
Hand 3 (1/485)
Head 3 (5/485) (2/5)
Heart 3 (1/485)
Hindbrain 3 (6/485)
Hindlimb 3 (1/485)
Liver 3 (1/485)
Lung 3 (1/485)
Mandibular process 3 (1/485) (2/5)
Maxillary process 3 (1/485) (2/5)
Midbrain 3 (1/485)
Nose 2 (1/51)
Oral cavity 3 (1/485)
3 (7/25) (4/5)
Skeleton 2 (1/51)
Skin 3 (1/485) (2/5)
Spinal cord 2 (1/50)
Tail 3 (1/485)
Tail somite 3 (1/485) (2/5)
Trachea 2 (1/50)
Urinary system 2 (1/50)


Associated Images

Associated Images
  • X-ray: XRay Images Lateral Orientation
    12 Images
  • X-ray: XRay Images Dorso Ventral
    12 Images
  • Embryo LacZ: LacZ images wholemount
    12 Images

Disease Models

No associations by disease annotation and gene orthology found.

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Lhx6tm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene
Lhx6tm1b(KOMP)Wtsi Reporter-tagged deletion allele (post-Cre)
Vector
Gene
Fixed Tissue