Gene: Mmp16

Order

Name matrix metallopeptidase 16

Synonyms
  • MT3-MMP
  • Membrane type 3-MMP

Status ES CellsMice
tm1a
Mice
tm1b
phenotype data available

Links MGI:1276107    Ensembl Gene    Ensembl Orthologs    My Genes   

Viability Homozygous - Viable

Phenotype associations for Mmp16

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Mmp16 data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
abnormal behavior Mmp16tm1b(EUCOMM)Wtsi HOM Female Male postnatal 2.88E-12
hyperactivity Mmp16tm1b(EUCOMM)Wtsi HOM Female Male postnatal 5.53E-12

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No (2/415) (2/2)
Aorta 2 No (2/2)
Bone 2 No (2/2)
Brain 2 No (2/2)
Brainstem 2 No (2/2)
Brown adipose tissue 2 No
Cartilage tissue 2 No (2/2)
Cerebellum 2 No (2/2)
Cerebral cortex 2 No (2/2)
Esophagus 2 No (7/415) (2/2)
Eye 2 No
Gall bladder 2 No (2/2)
Heart 2 No
Hippocampus 2 No (2/2)
Hypothalamus 2 No (2/2)
Kidney 2 No (18/584)
Large intestine 2 No (10/584) (2/2)
Liver 2 No
Lower urinary tract 2 No (1/2)
Lung 2 No
Lymph node 2 No (1/2)
Mammary gland 2 No
Olfactory lobe 2 No (2/2)
Oral epithelium 2 No (2/2)
Ovary 2 No (1/584)
Oviduct 2 No (1/2)
Pancreas 2 No (5/584)
Parathyroid gland 2 No (2/2)
Peripheral nervous system 2 No (2/2)
Peyer's patch 2 No
Pituitary gland 2 No (2/2)
Prostate gland 2 No (12/584) (1/2)
Skeletal muscle 2 No
Skin 2 No
Small intestine 2 No (9/584) (2/2)
Spinal cord 2 No (2/2)
Spleen 2 No (2/584)
Stomach 2 No (12/584) (2/2)
Striatum 2 No (2/2)
Testis 2 No (2/584) (1/2)
Thymus 2 No
Thyroid gland 2 No (15/584) (1/2)
Trachea 2 No (2/2)
Uterus 2 No (1/2)
Vascular system 2 No
White adipose tissue 2 No
Expression in Anatomogram

Tissues/organs lacZ+ expression

    endocrine system
    respiratory system
    digestive system
    cardiovascular system
    set of connective tissues
    reproductive system
    musculoskeletal system
    trunk
    postnatal mouse
    nervous system
    immune system
    exocrine system
    urinary system
No expression image was found for this adult tab

 Expression    No Expression    No Tissue Available    Ambiguous  

Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 1 (6/485) (3/3)
Ear 1 (1/485) (2/3)
Embryo 1 (1/485) (3/3)
Eye 1 (1/485) (3/3)
Foot 1 (1/485) (1/3)
Forebrain 1 (1/485) (3/3)
Forelimb 1 (1/485) (3/3)
Hand 1 (1/485) (1/3)
Head 1 (5/485) (3/3)
Heart 1 (1/485) (2/3)
Hindbrain 1 (6/485) (3/3)
Hindlimb 1 (1/485) (3/3)
Liver 1 (1/485) (2/3)
Lung 1 (1/485) (2/3)
Mandibular process 1 (1/485) (2/3)
Maxillary process 1 (1/485) (2/3)
Midbrain 1 (1/485) (3/3)
Oral cavity 1 (1/485) (2/3)
Skin 1 (1/485) (2/3)
Tail 1 (1/485) (3/3)
Tail somite 1 (1/485) (1/3)


Associated Images

Associated Images
  • Auditory Brain Stem Response: Click-evoked + 6 to 30kHz tone waveforms (pdf format)
    4 Images
  • Echo: M-Mode Images
    28 Images
  • Embryo LacZ: LacZ images wholemount
    4 Images
  • Adult LacZ: LacZ Images Wholemount
    17 Images

Disease Models

No associations by disease annotation and gene orthology found.

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Mmp16tm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene
Mmp16tm1b(EUCOMM)Wtsi Reporter-tagged deletion allele (post-Cre)
Vector
Gene