Gene: Pnn

Order

Name pinin

Synonyms D12Ertd512e

Status ES CellsMice
tm1
Mice
tm1.1
phenotype data available

Links MGI:1100514    Ensembl Gene    Ensembl Orthologs    My Genes   

Viability Homozygous - Lethal

Phenotype associations for Pnn

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Pnn data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
Eye with optic nerve - developmental and structural abnormality Pnntm1.1(KOMP)Vlcg HET Female Male postnatal 0.0
embryonic lethality prior to organogenesis Pnntm1.1(KOMP)Vlcg HOM Female Male embryonic day 9.5 0.0
embryonic lethality prior to tooth bud stage Pnntm1.1(KOMP)Vlcg HOM Female Male embryonic day 12.5 0.0
preweaning lethality, complete penetrance Pnntm1.1(KOMP)Vlcg HOM Female Male n/a 0.0

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No (5/393)
Aorta 2 No (1/562)
Brain 2 No (6/562) (2/2)
Brainstem 2 No (4/562) (2/2)
Cartilage tissue 2 No (1/562)
Cerebellum 2 No (4/562) (2/2)
Cerebral cortex 2 No (5/562) (2/2)
Esophagus 2 No (2/393)
Eye 2 No (1/562) (2/2)
Heart 2 No (3/562) (2/2)
Hippocampus 2 No (5/562) (2/2)
Hypothalamus 2 No (4/562) (2/2)
Kidney 2 No (20/562) (2/2)
Large intestine 2 No (12/562) (2/2)
Liver 2 No (2/2)
Lower urinary tract 2 No (3/562) (2/2)
Lung 2 No (3/562)
Lymph node 2 No (1/562)
Mammary gland 2 No
Olfactory lobe 2 No (4/393) (2/2)
Ovary 2 No (1/562) (1/2)
Oviduct 2 No (2/562) (1/2)
Pancreas 2 No (6/562) (1/2)
Peripheral nervous system 2 No (3/562)
Peyer's patch 2 No (1/393)
Pituitary gland 2 No (1/562)
Prostate gland 2 No (5/562) (1/2)
Skeletal muscle 2 No (2/2)
Skin 2 No (1/562)
Small intestine 2 No (11/562)
Spinal cord 2 No (3/562) (2/2)
Spleen 2 No (4/562)
Stomach 2 No (9/562) (2/2)
Striatum 2 No (4/562)
Testis 2 No (4/562) (1/2)
Thymus 2 No
Thyroid gland 2 No (16/562) (2/2)
Trachea 2 No (3/562)
Uterus 2 No (2/562) (1/2)
Vascular system 2 No (1/393)
White adipose tissue 2 No
Expression in Anatomogram

Tissues/organs lacZ+ expression

    postnatal mouse
    endocrine system digestive system
    cardiovascular system
    nervous system
    sensory organ
    reproductive system musculoskeletal system exocrine system
    trunk
    urinary system
No expression image was found for this adult tab

 Expression    No Expression    No Tissue Available    Ambiguous  

Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 8 (6/482) Image Only
Ear 8 (1/482) Image Only
Embryo 8 (1/482) Image Only
Eye 8 (1/482) Image Only
Foot 8 (1/482) Image Only
Forebrain 8 (1/482) Image Only
Forelimb 8 (1/482) Image Only
Hand 8 (1/482) Image Only
Head 8 (5/482) Image Only
Heart 8 (1/482) Image Only
Hindbrain 8 (6/482) Image Only
Hindlimb 8 (1/482) Image Only
Liver 8 (1/482) Image Only
Lung 8 (1/482) Image Only
Mandibular process 8 (1/482) Image Only
Maxillary process 8 (1/482) Image Only
Midbrain 8 (1/482) Image Only
Oral cavity 8 (1/482) Image Only
Skin 8 (1/482) Image Only
Tail 8 (1/482) Image Only
Tail somite 8 (1/482) Image Only


Associated Images

Associated Images
  • X-ray: XRay Images Skull Dorso Ventral Orientation
    10 Images
  • X-ray: XRay Images Lateral Orientation
    10 Images
  • Eye Morphology: Images Ophthalmoscopy
    8 Images
  • X-ray: XRay Images Skull Lateral Orientation
    10 Images
  • Embryo LacZ: LacZ images wholemount
    31 Images
  • Adult LacZ: LacZ Images Section
    8 Images
  • Gross Pathology and Tissue Collection
    6 Images
  • Combined SHIRPA and Dysmorphology
    1 Images
  • X-ray: XRay Images Dorso Ventral
    10 Images
  • Eye Morphology: Images Slit Lamp
    2 Images

Disease Models

No associations by disease annotation and gene orthology found.

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Pnntm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette)
Vector
Gene
Pnntm1.1(KOMP)Vlcg Reporter-tagged deletion allele (post Cre, with no selection cassette)
Vector
Gene
Pnntm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene