Gene: Pik3r2

Order

Name phosphoinositide-3-kinase regulatory subunit 2

Synonyms p85beta

Status ES CellsMice
tm1e
phenotype data available

Links MGI:1098772    Ensembl Gene    Ensembl Orthologs    My Genes   

Viability Homozygous - Viable

Phenotype associations for Pik3r2

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Pik3r2 data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
decreased body weight Pik3r2tm1e(KOMP)Wtsi HOM Female Male postnatal 3.26E-7
increased CD8-positive, alpha-beta T cell number Pik3r2tm1e(KOMP)Wtsi HOM Female Male postnatal 1.24E-5
decreased circulating creatinine level Pik3r2tm1e(KOMP)Wtsi HOM Female Male postnatal 4.55E-5
decreased granulocyte number Pik3r2tm1e(KOMP)Wtsi HOM Female Male postnatal 8.22E-5

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No (2/2)
Aorta 2 No
Blood vessel 2 No (2/2)
Bone 2 No (2/2)
Brain 2 No (2/2)
Brainstem 2 No
Brown adipose tissue 2 No
Cartilage tissue 2 No (2/2)
Cerebellum 2 No
Cerebral cortex 2 No
Eye 2 No (2/2)
Gall bladder 2 No
Heart 2 No (2/2)
Hippocampus 2 No
Hypothalamus 2 No
Kidney 2 No (18/584) (2/2)
Large intestine 2 No (10/584) (2/2)
Liver 2 No
Lower urinary tract 2 No (2/2)
Lung 2 No (2/2)
Lymph node 2 No (2/2)
Mammary gland 2 No
Esophagus 2 No (2/2)
Olfactory lobe 2 No
Ovary 2 No (1/584) (1/2)
Oviduct 2 No (1/2)
Pancreas 2 No (5/584) (2/2)
Parathyroid gland 2 No (2/2)
Peripheral nervous system 2 No (2/2)
Peyer's patch 2 No
Pituitary gland 2 No (2/2)
Prostate gland 2 No (12/584) (1/2)
Skeletal muscle tissue 2 No
Skin 2 No (2/2)
Small intestine 2 No (9/584) (2/2)
Spinal cord 2 No (2/2)
Spleen 2 No (2/584) (2/2)
Stomach 2 No (12/584) (2/2)
Striatum 2 No
Testis 2 No (2/584)
Thymus 2 No
Thyroid gland 2 No (15/584) (2/2)
Trachea 2 No (2/2)
Uterus 2 No (1/2)
White adipose tissue 2 No
Expression in Anatomogram

Tissues/organs lacZ+ expression

    endocrine system respiratory system digestive system cardiovascular system set of connective tissues reproductive system musculoskeletal system trunk postnatal mouse nervous system sensory organ immune system exocrine system integumental system urinary system
No expression image was found for this adult tab
No expression data was found for this embryo tab


Secondary lacZ Expression Data
postnatal mouse (22)
  • Pik3r2tm1e(KOMP)Wtsi
    large intestine, HET, Female, WTSI
  • Pik3r2tm1e(KOMP)Wtsi
    lung, HET, Female, WTSI
  • Pik3r2tm1e(KOMP)Wtsi
    thyroid gland, parathyroid gland, trachea, HET, Female, WTSI
  • Pik3r2tm1e(KOMP)Wtsi
    heart, HET, Female, WTSI
  • Pik3r2tm1e(KOMP)Wtsi
    kidney, HET, Female, WTSI

show all 22 images

trunk (15)
  • Pik3r2tm1e(KOMP)Wtsi
    large intestine, HET, Female, WTSI
  • Pik3r2tm1e(KOMP)Wtsi
    lung, HET, Female, WTSI
  • Pik3r2tm1e(KOMP)Wtsi
    thyroid gland, parathyroid gland, trachea, HET, Female, WTSI
  • Pik3r2tm1e(KOMP)Wtsi
    heart, HET, Female, WTSI
  • Pik3r2tm1e(KOMP)Wtsi
    kidney, HET, Female, WTSI

show all 15 images

nervous system (4)
  • Pik3r2tm1e(KOMP)Wtsi
    brain, HET, Female, WTSI
  • Pik3r2tm1e(KOMP)Wtsi
    brain, HET, Female, WTSI
  • Pik3r2tm1e(KOMP)Wtsi
    peripheral nervous system, pituitary gland, HET, Female, WTSI
  • Pik3r2tm1e(KOMP)Wtsi
    spinal cord, HET, Male, WTSI
digestive system (3)
  • Pik3r2tm1e(KOMP)Wtsi
    large intestine, HET, Female, WTSI
  • Pik3r2tm1e(KOMP)Wtsi
    stomach, oesophagus, HET, Female, WTSI
  • Pik3r2tm1e(KOMP)Wtsi
    small intestine, HET, Female, WTSI
reproductive system (3)
  • Pik3r2tm1e(KOMP)Wtsi
    ovary, oviduct, uterus, HET, Female, WTSI
  • Pik3r2tm1e(KOMP)Wtsi
    lower urinary tract, prostate gland, HET, Male, WTSI
  • Pik3r2tm1e(KOMP)Wtsi
    testis, HET, Male, WTSI
urinary system (3)
  • Pik3r2tm1e(KOMP)Wtsi
    kidney, HET, Female, WTSI
  • Pik3r2tm1e(KOMP)Wtsi
    lower urinary tract, prostate gland, HET, Male, WTSI
  • Pik3r2tm1e(KOMP)Wtsi
    urinary bladder, lower urinary tract, HET, Female, WTSI
cardiovascular system (2)
  • Pik3r2tm1e(KOMP)Wtsi
    heart, HET, Female, WTSI
  • Pik3r2tm1e(KOMP)Wtsi
    blood vessel, bone, cartilage tissue, HET, Female, WTSI
endocrine system (2)
  • Pik3r2tm1e(KOMP)Wtsi
    thyroid gland, parathyroid gland, trachea, HET, Female, WTSI
  • Pik3r2tm1e(KOMP)Wtsi
    adrenal gland, HET, Female, WTSI
immune system (2)
  • Pik3r2tm1e(KOMP)Wtsi
    lymph node, HET, Female, WTSI
  • Pik3r2tm1e(KOMP)Wtsi
    spleen, HET, Female, WTSI
respiratory system (2)
  • Pik3r2tm1e(KOMP)Wtsi
    lung, HET, Female, WTSI
  • Pik3r2tm1e(KOMP)Wtsi
    thyroid gland, parathyroid gland, trachea, HET, Female, WTSI
exocrine system (1)
  • Pik3r2tm1e(KOMP)Wtsi
    lower urinary tract, prostate gland, HET, Male, WTSI
integumental system (1)
  • Pik3r2tm1e(KOMP)Wtsi
    skin, HET, Female, WTSI
musculoskeletal system (1)
  • Pik3r2tm1e(KOMP)Wtsi
    blood vessel, bone, cartilage tissue, HET, Female, WTSI
sensory organ (1)
  • Pik3r2tm1e(KOMP)Wtsi
    eye, HET, Female, WTSI
set of connective tissues (1)
  • Pik3r2tm1e(KOMP)Wtsi
    blood vessel, bone, cartilage tissue, HET, Female, WTSI

Associated Images

Legacy Phenotype Associated Images
Xray (77)
  • Pik3r2tm1e(KOMP)Wtsi
    head, HOM, Male, WTSI
  • Pik3r2tm1e(KOMP)Wtsi
    forearm, HOM, Male, WTSI
  • Pik3r2tm1e(KOMP)Wtsi
    body, HOM, Male, WTSI
  • Pik3r2tm1e(KOMP)Wtsi
    body, HOM, Male, WTSI
  • Pik3r2tm1e(KOMP)Wtsi
    head, HOM, Male, WTSI

show all 77 images

Skin Histopathology (1)
  • Pik3r2tm1e(KOMP)Wtsi
    back skin, HOM, Female, WTSI

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Pik3r2tm1e(KOMP)Wtsi Targeted, non-conditional allele
Vector
Gene
Pik3r2tm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene