Gene: Crybg1

Order

Name crystallin beta-gamma domain containing 1

Synonyms Aim1

Status ES CellsMice
tm1a
Mice
tm1b
phenotype data available

Links MGI:109544    Ensembl Gene    Ensembl Orthologs    My Genes   

Viability Homozygous - Lethal

Phenotype associations for Crybg1

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Crybg1 data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
abnormal embryo size Crybg1tm1b(KOMP)Wtsi HET Female Male embryonic day 9.5 0.0
abnormal eye morphology Crybg1tm1b(KOMP)Wtsi HET Female postnatal 0.0
abnormal forebrain development Crybg1tm1b(KOMP)Wtsi HET Female Male embryonic day 9.5 0.0
abnormal hindbrain development Crybg1tm1b(KOMP)Wtsi HET Female Male embryonic day 9.5 0.0
abnormal midbrain development Crybg1tm1b(KOMP)Wtsi HET Female Male embryonic day 9.5 0.0
abnormal neural tube closure Crybg1tm1b(KOMP)Wtsi HET Female Male embryonic day 9.5 0.0
embryonic lethality prior to organogenesis Crybg1tm1b(KOMP)Wtsi HOM Female Male embryonic day 9.5 0.0
embryonic lethality prior to tooth bud stage Crybg1tm1b(KOMP)Wtsi HOM Female Male embryonic day 12.5 0.0
preweaning lethality, complete penetrance Crybg1tm1b(KOMP)Wtsi HOM Female Male n/a 0.0
decreased prepulse inhibition Crybg1tm1b(KOMP)Wtsi HET Female Male postnatal 8.1E-15
hypoactivity Crybg1tm1b(KOMP)Wtsi HET Female Male postnatal 2.41E-5

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
No expression data was found for this adult tab
No expression image was found for this adult tab

 Expression    No Expression    No Tissue Available    Ambiguous  

Anatomy #HET Specimens WT Expr Mutant Expr Images
Axial skeleton 2 (1/51) (2/2)
Brain 16 (6/485)
Central nervous system ganglion 2 (1/51)
Ear 16 (1/485) (2/16)
Embryo 16 (1/485) (2/16)
Eye 16 (1/485) (2/16)
Foot 16 (1/485)
Forebrain 16 (1/485)
Forelimb 16 (1/485)
Gut 2 (1/50)
Hand 16 (1/485)
Head 16 (5/485)
Heart 16 (1/485) (2/16)
Hindbrain 16 (6/485)
Hindlimb 16 (1/485)
Liver 16 (1/485)
Lung 16 (1/485)
Mandibular process 16 (1/485)
Maxillary process 16 (1/485) (2/16)
Midbrain 16 (1/485)
Nose 2 (1/51)
Oral cavity 16 (1/485)
Skeleton 2 (1/51)
Skin 16 (1/485)
Spinal cord 2 (1/50)
Tail 16 (1/485)
Tail somite 16 (1/485)
Trachea 2 (1/50)
Urinary system 2 (1/50) (2/2)


Associated Images

Associated Images
  • X-ray: XRay Images Lateral Orientation
    10 Images
  • X-ray: XRay Images Skull Lateral Orientation
    10 Images
  • X-ray: XRay Images Dorso Ventral
    10 Images
  • X-ray: XRay Images Skull Dorso Ventral Orientation
    10 Images
  • Gross Pathology and Tissue Collection
    9 Images
  • Eye Morphology: Images Ophthalmoscopy
    6 Images
  • Eye Morphology: Images Slit Lamp
    2 Images

Disease Models

No associations by disease annotation and gene orthology found.

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Crybg1tm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene
Crybg1tm1b(KOMP)Wtsi Reporter-tagged deletion allele (post-Cre)
Vector
Gene