Gene: Cpt2

Order

Name carnitine palmitoyltransferase 2

Synonyms
  • CPTII
  • CPT II

Status ES CellsMice
tm1a
Mice
tm1b
phenotype data available

Links MGI:109176    Ensembl Gene    Ensembl Orthologs    My Genes   

Viability Homozygous - Subviable

Phenotype associations for Cpt2

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Cpt2 data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
preweaning lethality, incomplete penetrance Cpt2tm1b(KOMP)Wtsi HOM Female Male n/a 0.0
increased circulating phosphate level Cpt2tm1b(KOMP)Wtsi HET Female Male postnatal 9.25E-7
abnormal vertebrae morphology Cpt2tm1b(KOMP)Wtsi HET Male postnatal 4.29E-6

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No (2/2)
Aorta 2 No
Blood vessel 2 No
Bone 2 No
Brain 2 No (2/2)
Brainstem 2 No (2/2)
Brown adipose tissue 2 No (2/2)
Cartilage tissue 2 No (2/2)
Cerebellum 2 No (2/2)
Cerebral cortex 2 No (2/2)
Eye 2 No
Gall bladder 2 No (1/2)
Heart 2 No (2/2)
Hippocampus 2 No (2/2)
Hypothalamus 2 No (2/2)
Kidney 2 No (18/584) (2/2)
Large intestine 2 No (10/584) (2/2)
Liver 2 No (2/2)
Lower urinary tract 2 No (2/2)
Lung 2 No (2/2)
Lymph node 2 No
Mammary gland 2 No
Esophagus 2 No (2/2)
Olfactory lobe 2 No (2/2)
Ovary 2 No (1/584) (1/2)
Oviduct 2 No (1/2)
Pancreas 2 No (5/584) (2/2)
Parathyroid gland 2 No (2/2)
Peripheral nervous system 2 No (2/2)
Peyer's patch 2 No (2/2)
Pituitary gland 2 No (2/2)
Prostate gland 2 No (12/584)
Skeletal muscle tissue 2 No (2/2)
Skin 2 No (1/2)
Small intestine 2 No (9/584) (2/2)
Spinal cord 2 No (2/2)
Spleen 2 No (2/584)
Stomach 2 No (12/584) (2/2)
Striatum 2 No (2/2)
Testis 2 No (2/584) (1/2)
Thymus 2 No (2/2)
Thyroid gland 2 No (15/584) (2/2)
Trachea 2 No (2/2)
Uterus 2 No
White adipose tissue 2 No
Expression in Anatomogram

Tissues/organs lacZ+ expression

    endocrine system respiratory system digestive system cardiovascular system set of connective tissues reproductive system musculoskeletal system adipose tissue trunk postnatal mouse nervous system immune system integumental system urinary system
No expression image was found for this adult tab
No expression data was found for this embryo tab


Secondary lacZ Expression Data
postnatal mouse (21)
  • Cpt2tm1b(KOMP)Wtsi
    brown adipose tissue, HET, Female, WTSI
  • Cpt2tm1b(KOMP)Wtsi
    pancreas, HET, Female, WTSI
  • Cpt2tm1b(KOMP)Wtsi
    small intestine, HET, Female, WTSI
  • Cpt2tm1b(KOMP)Wtsi
    bone, rib, HET, Female, WTSI
  • Cpt2tm1b(KOMP)Wtsi
    heart, HET, Female, WTSI

show all 21 images

trunk (17)
  • Cpt2tm1b(KOMP)Wtsi
    pancreas, HET, Female, WTSI
  • Cpt2tm1b(KOMP)Wtsi
    small intestine, HET, Female, WTSI
  • Cpt2tm1b(KOMP)Wtsi
    bone, rib, HET, Female, WTSI
  • Cpt2tm1b(KOMP)Wtsi
    heart, HET, Female, WTSI
  • Cpt2tm1b(KOMP)Wtsi
    thymus, HET, Female, WTSI

show all 17 images

digestive system (5)
  • Cpt2tm1b(KOMP)Wtsi
    small intestine, HET, Female, WTSI
  • Cpt2tm1b(KOMP)Wtsi
    stomach, HET, Female, WTSI
  • Cpt2tm1b(KOMP)Wtsi
    liver, HET, Male, WTSI
  • Cpt2tm1b(KOMP)Wtsi
    liver, HET, Female, WTSI
  • Cpt2tm1b(KOMP)Wtsi
    large intestine, HET, Male, WTSI
nervous system (3)
  • Cpt2tm1b(KOMP)Wtsi
    spinal cord, HET, Male, WTSI
  • Cpt2tm1b(KOMP)Wtsi
    pituitary gland, HET, Female, WTSI
  • Cpt2tm1b(KOMP)Wtsi
    hypothalamus, HET, Female, WTSI
reproductive system (2)
  • Cpt2tm1b(KOMP)Wtsi
    testis, HET, Male, WTSI
  • Cpt2tm1b(KOMP)Wtsi
    oviduct, HET, Female, WTSI
respiratory system (2)
  • Cpt2tm1b(KOMP)Wtsi
    lung, HET, Male, WTSI
  • Cpt2tm1b(KOMP)Wtsi
    trachea, HET, Female, WTSI
urinary system (2)
  • Cpt2tm1b(KOMP)Wtsi
    kidney, HET, Female, WTSI
  • Cpt2tm1b(KOMP)Wtsi
    lower urinary tract, urinary bladder, HET, Male, WTSI
adipose tissue (1)
  • Cpt2tm1b(KOMP)Wtsi
    brown adipose tissue, HET, Female, WTSI
cardiovascular system (1)
  • Cpt2tm1b(KOMP)Wtsi
    heart, HET, Female, WTSI
endocrine system (1)
  • Cpt2tm1b(KOMP)Wtsi
    adrenal gland, HET, Female, WTSI
immune system (1)
  • Cpt2tm1b(KOMP)Wtsi
    thymus, HET, Female, WTSI
integumental system (1)
  • Cpt2tm1b(KOMP)Wtsi
    skin, HET, Male, WTSI
musculoskeletal system (1)
  • Cpt2tm1b(KOMP)Wtsi
    bone, rib, HET, Female, WTSI
set of connective tissues (1)
  • Cpt2tm1b(KOMP)Wtsi
    brown adipose tissue, HET, Female, WTSI

Associated Images

Associated Images
  • Anti-nuclear antibody assay
    6 Images
  • X-ray: XRay Images Dorso Ventral
    42 Images
  • X-ray: XRay Images Skull Lateral Orientation
    14 Images
  • X-ray: XRay Images Skull Dorso Ventral Orientation
    14 Images
  • X-ray: XRay Images Lateral Orientation
    28 Images
  • X-ray: XRay Images Forepaw
    14 Images
  • DSS Histology
    8 Images
  • Eye Morphology: Images Slit Lamp
    1 Images
Legacy Phenotype Associated Images
Xray (70)
  • Cpt2tm1b(KOMP)Wtsi
    HET, Female, WTSI
  • Cpt2tm1b(KOMP)Wtsi
    HET, Female, WTSI
  • Cpt2tm1b(KOMP)Wtsi
    HET, Female, WTSI
  • Cpt2tm1b(KOMP)Wtsi
    HET, Female, WTSI
  • Cpt2tm1b(KOMP)Wtsi
    HET, Female, WTSI

show all 70 images

Histology Slide (7)
  • Cpt2tm1b(KOMP)Wtsi
    TS20 yolk sac, HET, Male, WTSI
  • Cpt2tm1b(KOMP)Wtsi
    TS20 stomach, HET, Male, WTSI
  • Cpt2tm1b(KOMP)Wtsi
    TS20 eye, HET, Male, WTSI
  • Cpt2tm1b(KOMP)Wtsi
    TS20 liver, HET, Male, WTSI
  • Cpt2tm1b(KOMP)Wtsi
    TS20 skin, HET, Male, WTSI

show all 7 images

Eye Morphology (1)
  • Cpt2tm1b(KOMP)Wtsi
    Fused cornea and lens, HET, Female, WTSI

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Cpt2tm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene
Cpt2tm1b(KOMP)Wtsi Reporter-tagged deletion allele (post-Cre)
Vector
Gene
Cpt2tm356689(L1L2_Bact_P)
Vector
Gene
Cpt2tm36516(L1L2_Bact_P)
Vector
Gene