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Gene: Vegfc MGI:109124

Registered for phenotyping at IMPC

Phenotyping is planned for a knockout strain of this gene but data is not currently available.

Gene Summary

Name:

vascular endothelial growth factor C

Synonyms:

VEGF-C

Order Alleles

IMPC Data Collections

No Body Weight Data
No Embryo Imaging Data
No Viability Data

IMPC Phenotype Summary

Significant

Not Significant

Not tested

View all our phenotype data below

Phenotypes

The IMPC applies a panel of phenotyping screens to characterise single-gene knockout mice by comparison to wild types. Click on the different tabs to visualise significant phenotypes identified by the IMPC, as well as all data that was measured.

lacZ Expression

Expression data not available

Associated Images

Images submitted by IMPC centres for a selection of procedures. Each set of images is available to view in our image comparator.

Phenotype associated images not available

Human diseases caused by Vegfc mutations

The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.

Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.

Human diseases associated with Vegfc (1 diseases)
Human diseases predicted to be associated with Vegfc (340 diseases)

The table below shows human diseases associated to Vegfc by orthology or direct annotation.

Disease	Similarity of phenotypes	Matching phenotypes	Source
Lymphatic Malformation 4		Pedal edema, Lymphedema	OMIM:615907

The table below shows human diseases predicted to be associated to Vegfc by phenotypic similarity.

Disease	Matching phenotypes	Source
Nuchal Bleb, Familial	Stillbirth, Fetal cystic hygroma, Hydrops fetalis	OMIM:257350
Hemolytic Disease Of Fetus And Newborn, Rh-Induced	Fetal ascites, Polyhydramnios, Splenomegaly, Hydrops fetalis, Fetal pericardial effusion, Fetal p...	OMIM:619462
Lymphatic Malformation 9	Tortuous lymphatic vessels, Predominantly lower limb lymphedema	OMIM:619319
Lymphatic Malformation 11	Pedal edema, Lymphedema	OMIM:619401
Gjc2-Related Late-Onset Primary Lymphedema	Genital edema, Predominantly lower limb lymphedema, Edema of the dorsum of hands, Venous insuffic...	ORPHA:568051
Lymphedema And Cerebral Arteriovenous Anomaly	Pulmonary arterial hypertension, Lymphedema	OMIM:152900
Ascites, Chylous	Chylous ascites	OMIM:208300
Lymphangioleiomyomatosis	Pulmonary lymphangiomyomatosis	OMIM:606690
Lymphatic Malformation 2	Lymphedema	OMIM:611944
Idiopathic Steroid-Sensitive Nephrotic Syndrome	Lymphedema	ORPHA:69061
Lymphatic Malformation 3	Lymphedema	OMIM:613480
Yellow Nail Syndrome	Hypoplasia of lymphatic vessels, Predominantly lower limb lymphedema, Lymphedema	OMIM:153300
Hydrops Fetalis, Nonimmune	Nonimmune hydrops fetalis, Hydrops fetalis	OMIM:236750
Lymphatic Malformation 5	Facial edema, Hypoplasia of lymphatic vessels, Predominantly lower limb lymphedema	OMIM:153200
Lymphatic Malformation 1	Prominent superficial veins, Predominantly lower limb lymphedema, Nonimmune hydrops fetalis, Hypo...	OMIM:153100
Chylous Ascites	Ascites, Lymphedema	ORPHA:1160
Lymphangiectasia, Pulmonary, Congenital	Palpebral edema, Nonimmune hydrops fetalis, Polyhydramnios, Edema, Facial edema, Chylous ascites,...	OMIM:265300
Lymphatic Malformation 8	Nonimmune hydrops fetalis, Polyhydramnios, Pericardial effusion, Stillbirth, Pleural effusion, Ge...	OMIM:618773
Choanal Atresia And Lymphedema	Pericardial effusion, Lymphedema	OMIM:613611
Hydrops Fetalis	Nonimmune hydrops fetalis, Polyhydramnios, Lymphedema, Pericardial effusion, Abnormality of the l...	ORPHA:1041
Follicular Lymphoma	Lymphedema, Splenomegaly, Mediastinal lymphadenopathy, Lymphadenopathy, Pleural effusion	ORPHA:545
Fetal Parvovirus Syndrome	Hypertrophic cardiomyopathy, Increased nuchal translucency, Ascites, Hydrops fetalis	ORPHA:295
Hydrops Fetalis, Nonimmune, With Gracile Bones And Dysmorphism	Hydrops fetalis, Nonimmune hydrops fetalis, Polyhydramnios	OMIM:613124
Cardiomyopathy, Familial Restrictive, 6	Hepatomegaly, Pulmonary insufficiency, Tricuspid regurgitation, Hydrops fetalis, Pulmonic stenosi...	OMIM:619433
Lymphatic Malformation 7	Nonimmune hydrops fetalis, Edema, Lymphedema, Facial edema, Pericardial effusion, Increased nucha...	OMIM:617300
Ovarian Hyperstimulation Syndrome	Ascites	OMIM:608115
Meige Disease	Predominantly lower limb lymphedema, Edema of the dorsum of hands, Facial edema, Periorbital edem...	ORPHA:90186
Lymphatic Malformation 10	Lymphedema	OMIM:619369
Congenital Pulmonary Lymphangiectasia	Hepatomegaly, Tricuspid regurgitation, Splenomegaly, Congestive heart failure, Hydrops fetalis, C...	ORPHA:2414
Hypotrichosis-Lymphedema-Telangiectasia-Renal Defect Syndrome	Plantar telangiectasia, Predominantly lower limb lymphedema, Palpebral edema, Abnormality of the ...	ORPHA:69735
Lymphatic Malformation 4	Pedal edema, Lymphedema	OMIM:615907
Lymphatic Malformation 12	Nonimmune hydrops fetalis, Fetal ascites, Polyhydramnios, Lymphedema, Fetal pericardial effusion,...	OMIM:620014
Chondrodysplasia, Blomstrand Type	Premature birth, Fetal ascites, Polyhydramnios, Hydrops fetalis, Stillbirth, Preductal coarctatio...	OMIM:215045
Cholestasis-Lymphedema Syndrome	Hepatomegaly, Splenomegaly, Lymphedema	OMIM:214900
Nephrosialidosis	Pericardial effusion, Ascites	OMIM:256150
Dysplastic Cortical Hyperostosis, Kozlowski-Tsuruta Type	Splenomegaly, Hydrops fetalis, Polyhydramnios	ORPHA:2204
Hennekam Lymphangiectasia-Lymphedema Syndrome 2	Intestinal lymphangiectasia, Pericardial lymphangiectasia, Pulmonary lymphangiectasia, Lymphedema	OMIM:616006
Cholestasis-Lymphedema Syndrome	Gastrointestinal hemorrhage, Hepatomegaly, Portal hypertension, Lymphedema, Splenomegaly, Abnorma...	ORPHA:1414
Umbilical Cord Ulceration-Intestinal Atresia Syndrome	Single umbilical artery, Abnormal aortic morphology, Hydrops fetalis, Polyhydramnios	ORPHA:3405
Lissencephaly 2	Lymphedema	OMIM:257320
Focal Segmental Glomerulosclerosis 1	Hypertension, Pleural effusion, Ascites, Edema	OMIM:603278
Alpha-Heavy Chain Disease	Hepatomegaly, Splenomegaly, Ascites, Lymphadenopathy	ORPHA:100025
Indomethacin Embryofetopathy	Premature birth, Hydrops fetalis, Oligohydramnios	ORPHA:1909
Lymphangiectasia, Intestinal	Intestinal lymphangiectasia, Stillbirth, Edema, Pedal edema	OMIM:152800
Achondrogenesis, Type Ib	Polyhydramnios, Edema, Breech presentation, Hydrops fetalis, Stillbirth	OMIM:600972
Lymphatic Malformation 6	Genital edema, Nonimmune hydrops fetalis, Polyhydramnios, Edema, Facial edema, Periorbital edema,...	OMIM:616843
Developmental And Epileptic Encephalopathy 96	Hydrops fetalis	OMIM:619340
Ulnar Agenesis And Endocardial Fibroelastosis	Neonatal death, Hydrops fetalis	OMIM:276822
Diffuse Neonatal Hemangiomatosis	Premature birth, Polyhydramnios, Patent ductus arteriosus, Hydrops fetalis, Ascites	ORPHA:2123
Palmoplantar Keratoderma-Esophageal Carcinoma Syndrome	Gastrointestinal hemorrhage, Hepatomegaly, Ascites	ORPHA:2198
Fetal Gaucher Disease	Decreased fetal movement, Fetal akinesia sequence, Abnormality of the spleen, Splenomegaly, Hydro...	ORPHA:85212
Dohle Bodies And Leukemia	Lymphedema	OMIM:223350
Splenoportal Vascular Anomalies	Splenomegaly, Ascites	OMIM:271500
Campomelia, Cumming Type	Polysplenia, Lymphedema	OMIM:211890
Hb Bart'S Hydrops Fetalis	Splenomegaly, Hydrops fetalis, Polyhydramnios, Oligohydramnios	ORPHA:163596
Glycogen Storage Disease Iv	Polyhydramnios, Edema, Portal hypertension, Hydrops fetalis, Hepatosplenomegaly, Cardiomyopathy, ...	OMIM:232500
Secondary Intestinal Lymphangiectasia	Intestinal lymphedema, Edema, Lymphedema, Right ventricular failure, Chylous ascites, Intestinal ...	ORPHA:90363
Alpha-N-Acetylgalactosaminidase Deficiency Type 1	Hepatomegaly, Telangiectasia of the skin, Lymphedema, Telangiectasia, Hypertrophic cardiomyopathy	ORPHA:79279
Pulmonary Edema Of Mountaineers, Susceptibility To	Elevated pulmonary artery pressure, Edema, Pulmonary edema	OMIM:178400
Lethal Hemolytic Anemia-Genital Anomalies Syndrome	Splenomegaly, Ascites, Polyhydramnios, Oligohydramnios	ORPHA:1046
Alpha-Thalassemia	Hypersplenism, Splenomegaly, Hydrops fetalis	ORPHA:846
Transaldolase Deficiency	Edema, Hydrops fetalis, Coarctation of aorta, Hepatosplenomegaly	ORPHA:101028
Polycystic Liver Disease 1 With Or Without Kidney Cysts	Ascites	OMIM:174050
Deafness-Lymphedema-Leukemia Syndrome	Hepatomegaly, Lymphedema, Splenomegaly, Lymphadenopathy, Intracranial hemorrhage	ORPHA:3226
Primary Intestinal Lymphangiectasia	Edema, Pericardial effusion, Abnormal lymphatic vessel morphology, Pleural effusion, Intestinal l...	ORPHA:90362
Congenital Disorder Of Glycosylation, Type Ik	Splenomegaly, Abnormality of the amniotic fluid, Nonimmune hydrops fetalis	OMIM:608540
Familial Atrial Myxoma	Tricuspid regurgitation, Congestive heart failure, Heart murmur, Pedal edema, Ascites	ORPHA:615
Sialidosis Type 2	Hepatomegaly, Splenomegaly, Hydrops fetalis, Pedal edema, Ascites	ORPHA:87876
Cinca Syndrome	Hepatosplenomegaly, Lymphadenopathy, Lymphedema	OMIM:607115
Hepatic Veno-Occlusive Disease	Hepatomegaly, Ascites	ORPHA:890
Lymphedema, Primary, With Myelodysplasia	Lymphedema	OMIM:614038
Pseudomyxoma Peritonei	Ascites, Lymphadenopathy	ORPHA:26790
Congenital Heart Block	Premature birth, Pericardial effusion, Patent ductus arteriosus, Hydrops fetalis, Peripheral edem...	ORPHA:60041
Melorheostosis	Lymphedema	ORPHA:2485
Kaposi Sarcoma	Abnormality of the spleen, Generalized lymphadenopathy, Lymphedema	ORPHA:33276
Portal Hypertension, Noncirrhotic, 2	Hepatomegaly, Epistaxis, Portal hypertension, Splenomegaly, Ascites	OMIM:619463
Infantile Sialic Acid Storage Disease	Hepatomegaly, Splenomegaly, Congestive heart failure, Hydrops fetalis, Ascites	OMIM:269920
Hennekam Lymphangiectasia-Lymphedema Syndrome 3	Polyhydramnios, Lymphedema	OMIM:618154
Milroy Disease	Predominantly lower limb lymphedema, Pedal edema, Lymphedema	ORPHA:79452
Lymphedema, Cardiac Septal Defects, And Characteristic Facies	Oligohydramnios, Atrial flutter, Hydrops fetalis, Lymphedema	OMIM:601927
Greenberg Dysplasia	Lymphedema	ORPHA:1426
Combined Oxidative Phosphorylation Deficiency 10	Pericardial effusion, Hypertrophic cardiomyopathy, Bradycardia, Pleural effusion, Ascites, Oligoh...	OMIM:614702
Cardiomyopathy, Familial Hypertrophic, 4	Hepatomegaly, Transient ischemic attack, Cardiac arrest, First degree atrioventricular block, Sud...	OMIM:115197
Long Qt Syndrome 3	Nonimmune hydrops fetalis, Hydrops fetalis	OMIM:603830
Lissencephaly 7 With Cerebellar Hypoplasia	Lymphedema	OMIM:616342
Klippel-Trénaunay Syndrome	Gastrointestinal hemorrhage, Hepatomegaly, Edema, Pulmonary embolism, Congestive heart failure, H...	ORPHA:90308
Lymphedema-Hypoparathyroidism Syndrome	Pulmonary lymphangiectasia, Lymphedema	OMIM:247410
Mitochondrial Complex I Deficiency, Nuclear Type 35	Neonatal death, Nonimmune hydrops fetalis	OMIM:619003
Yellow Nail Syndrome	Pulmonary arterial hypertension, Hypoplasia of lymphatic vessels, Lymphedema	ORPHA:662
Chromosome 1P36.33 Duplication Syndrome, Atad3 Gene Cluster, Autosomal Dominant	Hydrops fetalis, Fetal akinesia sequence	OMIM:618815
Kaposiform Lymphangiomatosis	Epidural hemorrhage, Pericardial effusion, Splenomegaly, Abnormality of the lymphatic system, Hep...	ORPHA:464329
Congenital Toxoplasmosis	Hepatomegaly, Ascites, Lymphadenopathy	ORPHA:858
Aplasia Cutis Congenita-Intestinal Lymphangiectasia Syndrome	Lymphedema	ORPHA:1116
Cirrhotic Cardiomyopathy	Prolonged QT interval, Hepatomegaly, Elevated jugular venous pressure, Left ventricular diastolic...	ORPHA:57777
Maternal Uniparental Disomy Of Chromosome X	Congestive heart failure, Predominantly lower limb lymphedema	ORPHA:261519
Capillary Malformation-Arteriovenous Malformation	Nonimmune hydrops fetalis, Epistaxis, Lymphedema, High-output congestive heart failure, Congestiv...	ORPHA:137667
Achondrogenesis	Thickened nuchal skin fold, Hydrops fetalis, Polyhydramnios	ORPHA:932
Klippel-Trenaunay-Weber Syndrome	Lymphangioma, Lymphedema	OMIM:149000
Cronkhite-Canada Syndrome	Hepatomegaly, Splenomegaly, Lymphedema	ORPHA:2930
Ovarian Hyperstimulation Syndrome	Pulmonary edema, Hypovolemia, Capillary leak, Peripheral edema, Pleural effusion, Ascites, Genera...	ORPHA:64739
Mucopolysaccharidosis Type 7	Splenomegaly, Ascites, Hydrops fetalis, Lymphedema	ORPHA:584
Neuraminidase Deficiency	Bone-marrow foam cells, Facial edema, Splenomegaly, Hydrops fetalis, Cherry red spot of the macul...	OMIM:256550
Mullerian Derivatives, Persistence Of, With Lymphangiectasia And Postaxial Polydactyly	Hepatomegaly, Polyhydramnios, Thyroid lymphangiectasia, Lymphedema, Splenomegaly, Pancreatic lymp...	OMIM:235255
Hemochromatosis, Type 1	Hepatomegaly, Splenomegaly, Congestive heart failure, Telangiectasia, Cardiomyopathy, Arrhythmia,...	OMIM:235200
Alpha-N-Acetylgalactosaminidase Deficiency	Lymphedema	ORPHA:3137
Congenital Disorder Of Glycosylation, Type Iir	Hepatomegaly, Ascites	OMIM:301045
Chromomycosis	Lymphangiectasis, Predominantly lower limb lymphedema, Edema, Lymphedema	ORPHA:182
Familial Exudative Vitreoretinopathy	Macular telangiectasia, Lymphedema, Macular edema, Vitreous hemorrhage, Retinal neovascularization	ORPHA:891
Idiopathic Neonatal Atrial Flutter	Hydrops fetalis, Fetal distress	ORPHA:45452
Achondrogenesis Type 1B	Thickened nuchal skin fold, Hydrops fetalis, Polyhydramnios	ORPHA:93298
Congenital Disorder Of Glycosylation, Type Ib	Lymphangiectasis, Edema	OMIM:602579
Malignant Peritoneal Mesothelioma	Ascites, Pedal edema	ORPHA:168811
Capillary Malformation Of The Lower Lip, Lymphatic Malformation Of Face And Neck, Asymmetry Of Face And Limbs, And Partial/Generalized Overgrowth	Lymphedema	OMIM:613089
Hypotrichosis-Lymphedema-Telangiectasia-Renal Defect Syndrome	Palpebral edema, Nonimmune hydrops fetalis, Lymphedema, Pulmonary lymphangiectasia, Telangiectasi...	OMIM:137940
Free Sialic Acid Storage Disease	Splenomegaly, Ascites, Hydrops fetalis, Hepatomegaly	ORPHA:834
Tenosynovial Giant Cell Tumor	Joint swelling, Lymphedema	ORPHA:66627
Achondrogenesis Type 1A	Thickened nuchal skin fold, Hydrops fetalis, Polyhydramnios	ORPHA:93299
Al-Gazali-Bakalinova Syndrome	Lymphedema	OMIM:607131
Hypotrichosis-Lymphedema-Telangiectasia Syndrome	Palmar telangiectasia, Predominantly lower limb lymphedema, Nonimmune hydrops fetalis, Palpebral ...	OMIM:607823
Fabry Disease	Transient ischemic attack, Angina pectoris, Myocardial infarction, Lymphedema, Congestive heart f...	OMIM:301500
Complement Hyperactivation, Angiopathic Thrombosis, And Protein-Losing Enteropathy	Hepatomegaly, Edema, Pulmonary embolism, Budd-Chiari syndrome, Intestinal lymphangiectasia, Ascit...	OMIM:226300
Congenital Disorder Of Glycosylation, Type Il	Hepatomegaly, Edema, Pericardial effusion, Hepatosplenomegaly, Ascites	OMIM:608776
Ring Chromosome 22 Syndrome	Pleural effusion, Edema, Lymphedema	ORPHA:1446
Tempi Syndrome	Intracranial hemorrhage, Transudative pleural effusion, Ascites, Telangiectasia	ORPHA:284227
Boomerang Dysplasia	Hydrops fetalis, Polyhydramnios	ORPHA:1263
Monosomy 18P	Hypertension, Lymphedema	ORPHA:1598
Lymphoproliferative Syndrome 2	Hepatomegaly, Splenomegaly, Lymphadenopathy, Hepatosplenomegaly, Ascites	OMIM:615122
Hemolytic Anemia Due To Red Cell Pyruvate Kinase Deficiency	Splenomegaly, Hydrops fetalis	ORPHA:766
Congenital Myopathy 1B, Autosomal Recessive	Decreased fetal movement, Hydrops fetalis, Polyhydramnios	OMIM:255320
German Syndrome	Lymphedema	ORPHA:2077
Aplasia Cutis Congenita With Intestinal Lymphangiectasia	Intestinal lymphangiectasia, Generalized edema	OMIM:207731
Parkes Weber Syndrome	Peripheral arteriovenous fistula, Cerebral arteriovenous malformation, Subarachnoid hemorrhage, V...	ORPHA:90307
Cantu Syndrome	Pericardial effusion, Lymphedema	OMIM:239850
Combined Oxidative Phosphorylation Defect Type 27	Nonimmune hydrops fetalis	ORPHA:477774
Glycogen Storage Disease Of Heart, Lethal Congenital	Prolonged QRS complex, Left axis deviation, Pericardial effusion, Congestive heart failure, ST se...	OMIM:261740
Glycogen Storage Disease Due To Glycogen Branching Enzyme Deficiency	Hepatomegaly, Nonimmune hydrops fetalis, Polyhydramnios, Portal hypertension, Congestive heart fa...	ORPHA:367
Ovarian Fibroma	Pleural effusion, Ascites	ORPHA:314473
Lymphangioleiomyomatosis	Gastrointestinal hemorrhage, Lymphedema, Abnormality of the lymphatic system, Chylopericardium, L...	ORPHA:538
Hemochromatosis, Neonatal	Nonimmune hydrops fetalis, Oligohydramnios	OMIM:231100
Dengue Fever	Gastrointestinal hemorrhage, Hepatomegaly, Epistaxis, Cerebral hemorrhage, Hypotension, Ascites	ORPHA:99828
Hennekam Lymphangiectasia-Lymphedema Syndrome 1	Pericardial lymphangiectasia, Nonimmune hydrops fetalis, Lymphedema, Periorbital edema, Pericardi...	OMIM:235510
Combined Oxidative Phosphorylation Deficiency 5	Hypertrophic cardiomyopathy, Ascites, Edema	OMIM:611719
Microcephaly With Or Without Chorioretinopathy, Lymphedema, Or Impaired Intellectual Development	Lymphedema	OMIM:152950
Desmoplastic Small Round Cell Tumor	Hepatomegaly, Mediastinal lymphadenopathy, Ascites, Lymphadenopathy	ORPHA:83469
Wolman Disease	Splenomegaly, Ascites, Hepatomegaly	ORPHA:75233
Mulibrey Nanism	Hepatomegaly, Ascites, Hydrops fetalis, Congestive heart failure	OMIM:253250
Lymphedema-Distichiasis Syndrome	Predominantly lower limb lymphedema, Nonimmune hydrops fetalis, Lymphedema, Chylothorax, Arrhythmia	OMIM:153400
Campomelia, Cumming Type	Hepatomegaly, Oligohydramnios, Hydrops fetalis, Lymphedema	ORPHA:1318
Idiopathic Steroid-Sensitive Nephrotic Syndrome With Secondary Steroid Resistance	Palpebral edema, Edema, Pulmonary embolism, Facial edema, Pedal edema, Hypertension, Anasarca, Pl...	ORPHA:567546
Achondrogenesis, Type Ii	Polyhydramnios, Stillbirth, Hydrops fetalis, Edema	OMIM:200610
Hypocomplementemic Urticarial Vasculitis	Hepatomegaly, Pericardial effusion, Splenomegaly, Angioedema, Lymphadenopathy, Small vessel vascu...	ORPHA:36412
Hydrops, Lactic Acidosis, And Sideroblastic Anemia	Nonimmune hydrops fetalis, Hypertension, Second degree atrioventricular block, Pulmonary arterial...	OMIM:617021
Lymphatic Malformation 13	Nonimmune hydrops fetalis, Lymphedema, Mitral regurgitation, Pulmonary arterial hypertension, Asc...	OMIM:620244
Congenital Enterovirus Infection	Decreased fetal movement, Premature birth, Fetal ascites, Polyhydramnios, Pericardial effusion, H...	ORPHA:292
Galactosialidosis	Cherry red spot of the macula, Nonimmune hydrops fetalis, Hepatosplenomegaly	OMIM:256540
Clapo Syndrome	Lymphangioma, Lymphedema	ORPHA:168984
Griscelli Syndrome	Hepatomegaly, Splenomegaly, Pedal edema, Lymphadenopathy, Ascites	ORPHA:381
Tropical Endomyocardial Fibrosis	Prolonged QRS complex, Restrictive cardiomyopathy, Atrioventricular block, Pedal edema, Left bund...	ORPHA:75565
Noonan Syndrome 13	Mitral regurgitation, Lymphedema	OMIM:619087
Budd-Chiari Syndrome	Gastrointestinal hemorrhage, Hepatomegaly, Portal hypertension, Splenomegaly, Ascites	ORPHA:131
Dahlberg-Borer-Newcomer Syndrome	Lymphedema	ORPHA:1563
Hennekam Syndrome	Lymphedema, Pericardial effusion, Splenomegaly, Pulmonary lymphangiectasia, Hydrops fetalis, Lymp...	ORPHA:2136
Aggressive Systemic Mastocytosis	Gastrointestinal hemorrhage, Portal hypertension, Hypersplenism, Lymphadenopathy, Hepatosplenomeg...	ORPHA:98850
Infantile Systemic Hyalinosis	Telangiectasia of the skin, Aplasia/Hypoplasia of the thymus, Lymphedema	ORPHA:2176
Niemann-Pick Disease, Type A	Hepatomegaly, Splenomegaly, Ascites, Lymphadenopathy	OMIM:257200
Cholestasis, Progressive Familial Intrahepatic, 3	Splenomegaly, Ascites, Hepatomegaly	OMIM:602347
Carney Triad	Gastrointestinal hemorrhage, Tachycardia, Mediastinal lymphadenopathy, Lymphadenopathy, Hypertens...	ORPHA:139411
Alg8-Cdg	Premature birth, Edema, Hydrops fetalis, Ascites, Oligohydramnios	ORPHA:79325
Eosinophilic Gastroenteritis	Hematochezia, Ascites, Edema	ORPHA:2070
Lymphatic Filariasis	Predominantly lower limb lymphedema, Lymphedema, Lymphadenitis, Abnormality of the lymphatic syst...	ORPHA:2035
Osteochondrodysplasia, Complex Lethal, Symoens-Barnes-Gistelinck Type	Polyhydramnios, Hydrops fetalis, Single umbilical artery, Pleural effusion, Ascites	OMIM:616897
Radioulnar Synostosis With Amegakaryocytic Thrombocytopenia 2	Hydrops fetalis	OMIM:616738
Combined Oxidative Phosphorylation Deficiency 40	Neonatal death, Premature birth, Nonimmune hydrops fetalis	OMIM:618835
Combined Oxidative Phosphorylation Deficiency 42	Neonatal death, Premature birth, Nonimmune hydrops fetalis	OMIM:618839
Combined Oxidative Phosphorylation Deficiency 41	Premature birth, Nonimmune hydrops fetalis	OMIM:618838
Pseudo-Torch Syndrome 2	Hepatomegaly, Cerebral hemorrhage, Bradycardia, Pleural effusion, Ascites	OMIM:617397
Cholestasis, Progressive Familial Intrahepatic, 5	Pleural effusion, Ascites, Nonimmune hydrops fetalis	OMIM:617049
Congenital Disorder Of Glycosylation, Type Ih	Hepatomegaly, Ascites, Edema, Oligohydramnios	OMIM:608104
Distal Xq28 Microduplication Syndrome	Predominantly lower limb lymphedema, Epistaxis, Upper eyelid edema	ORPHA:293939
Gaucher Disease Type 1	Hepatomegaly, Pericardial effusion, Splenomegaly, Hypersplenism, Pedal edema, Pulmonary arterial ...	ORPHA:77259
Immunodeficiency 80 With Or Without Congenital Cardiomyopathy	Pericardial effusion, Hypoplastic spleen, Hypoplasia of the thymus, Nonimmune hydrops fetalis	OMIM:619313
Hepatoportal Sclerosis	Gastrointestinal hemorrhage, Portal hypertension, Hypersplenism, Splenomegaly, Ascites	ORPHA:64743
Congenital Sialidosis Type 2	Hepatomegaly, Abnormal EKG, Edema, Hepatosplenomegaly, Telangiectasia, Ascites	ORPHA:93400
Trisomy 1Q	Increased nuchal translucency, Patent ductus arteriosus, Hydrops fetalis, Polyhydramnios	ORPHA:261344
Camptodactyly-Arthropathy-Coxa-Vara-Pericarditis Syndrome	Pericarditis, Ascites, Mitral regurgitation	ORPHA:2848
Necrotizing Enterocolitis	Shock, Edema, Bradycardia, Hypotension, Ascites	ORPHA:391673
Ovarian Fibrothecoma	Pleural effusion, Ascites	ORPHA:314478
Pediatric Systemic Lupus Erythematosus	Edema, Pericardial effusion, Raynaud phenomenon, Lymphadenopathy, Pleural effusion, Ascites	ORPHA:93552
Combined Oxidative Phosphorylation Deficiency 57	Neonatal death, Nonimmune hydrops fetalis, Fetal pleural effusion	OMIM:620167
Gracile Bone Dysplasia	Asplenia, Hypoplastic spleen, Ascites	OMIM:602361
Cirrhosis, Familial	Hypertension, Ascites, Pulmonary arterial hypertension	OMIM:215600
Poems Syndrome	Edema, Pericardial effusion, Lymphadenopathy, Pulmonary arterial hypertension, Pleural effusion, ...	ORPHA:2905
Trisomy 13	Patent ductus arteriosus, Hydrops fetalis	ORPHA:3378
Phakomatosis Pigmentokeratotica	Raynaud phenomenon, Arrhythmia, Lymphedema	ORPHA:2874
Lethal Congenital Contracture Syndrome 10	Overriding aorta, Fetal akinesia sequence, Hydrops fetalis, Hypoplasia of the thymus, Oligohydram...	OMIM:617022
Noonan Syndrome-Like Disorder With Or Without Juvenile Myelomonocytic Leukemia	Polyhydramnios, Lymphedema, Splenomegaly, Hepatosplenomegaly, Mitral regurgitation, Chylothorax, ...	OMIM:613563
Reynolds Syndrome	Hepatomegaly, Telangiectasia of the skin, Xerostomia, Ascites, Mucosal telangiectasiae	ORPHA:779
Platyspondylic Dysplasia, Torrance Type	Hydrops fetalis, Polyhydramnios	ORPHA:85166
Gaucher Disease, Perinatal Lethal	Decreased fetal movement, Premature birth, Nonimmune hydrops fetalis, Polyhydramnios, Splenomegal...	OMIM:608013
Primary Hepatic Neuroendocrine Carcinoma	Hepatomegaly, Chronic noninfectious lymphadenopathy, Right ventricular failure, Heart murmur, Pal...	ORPHA:100085
Alpha-N-Acetylgalactosaminidase Deficiency Type 2	Telangiectasia of the oral mucosa, Telangiectasia of the skin, Lip telangiectasia, Lymphedema	ORPHA:79280
Takenouchi-Kosaki Syndrome	Pulmonic stenosis, Lymphedema	OMIM:616737
Farber Disease	CNS foam cells, Hydrops fetalis, Lymphadenopathy, Hepatosplenomegaly, Joint swelling, Cherry red ...	ORPHA:333
Aicardi-Goutieres Syndrome 9	Hepatomegaly, Pericarditis, Edema, Portal hypertension, Pericardial effusion, Hepatosplenomegaly,...	OMIM:619487
Fabry Disease	Conjunctival telangiectasia, Bundle branch block, Angina pectoris, Transient ischemic attack, Tel...	ORPHA:324
Gm1 Gangliosidosis	Premature birth, Splenomegaly, Patent ductus arteriosus, Hydrops fetalis, Hepatosplenomegaly, Che...	ORPHA:354
Classic Galactosemia	Hepatomegaly, Ascites	ORPHA:79239
Bannayan-Riley-Ruvalcaba Syndrome	Intracranial hemorrhage, Telangiectasia, Angina pectoris, Lymphedema	ORPHA:109
Phelan-Mcdermid Syndrome	Palpebral edema, Lymphedema	OMIM:606232
Multifocal Lymphangioendotheliomatosis-Thrombocytopenia Syndrome	Gastrointestinal hemorrhage, Cerebral hemorrhage, Diffuse alveolar hemorrhage, Hematemesis, Retin...	ORPHA:464321
Achondrogenesis, Type Ia	Polyhydramnios, Increased nuchal translucency, Hydrops fetalis, Stillbirth, Absence of stomach bu...	OMIM:200600
Sclerosing Cholangitis, Neonatal	Splenomegaly, Ascites, Portal hypertension, Hepatomegaly	OMIM:617394
Fraser Syndrome 3	Sonographic non-visualized fetal bladder, Nonimmune hydrops fetalis, Stillbirth, Ascites, Oligohy...	OMIM:617667
Cerebrofacioarticular Syndrome	Pulmonic stenosis, Lymphedema	ORPHA:314679
Ectodermal Dysplasia And Immunodeficiency 1	Lymphedema	OMIM:300291
Diarrhea 10, Protein-Losing Enteropathy Type	Polyhydramnios, Pericardial effusion, Hematochezia, Anasarca, Pleural effusion, Ascites	OMIM:618183
Noonan Syndrome	Hepatomegaly, Lymphedema, Abnormality of the spleen, Abnormality of the lymphatic system, Arrhythmia	ORPHA:648
Autoimmune Hepatitis	Gastrointestinal hemorrhage, Splenomegaly, Ascites, Spider hemangioma	ORPHA:2137
Gm1-Gangliosidosis, Type I	Splenomegaly, Cherry red spot of the macula, Hydrops fetalis	OMIM:230500
Pyruvate Kinase Deficiency Of Red Cells	Splenomegaly, Nonimmune hydrops fetalis	OMIM:266200
Schneckenbecken Dysplasia	Stillbirth, Nonimmune hydrops fetalis, Polyhydramnios	OMIM:269250
Autosomal Recessive Spastic Paraplegia Type 11	Orthostatic hypotension, Lymphedema	ORPHA:2822
Mosaic Trisomy 9	Polyhydramnios, Asplenia, Patent ductus arteriosus, Hydrops fetalis, Single umbilical artery, Oli...	ORPHA:99776
Lymphedema-Distichiasis Syndrome	Arrhythmia, Predominantly lower limb lymphedema	ORPHA:33001
Hepatic Veno-Occlusive Disease-Immunodeficiency Syndrome	Hepatomegaly, Portal hypertension, Absence of lymph node germinal center, Hepatosplenomegaly, Asc...	ORPHA:79124
Eisenmenger Syndrome	Ventricular tachycardia, Pedal edema, Supraventricular tachycardia, Hepatomegaly, Tricuspid regur...	ORPHA:97214
Cardiofaciocutaneous Syndrome	Hypertrophic cardiomyopathy, Pulmonic stenosis, Lymphedema	ORPHA:1340
Müllerian Derivatives-Lymphangiectasia-Polydactyly Syndrome	Hepatomegaly, Polyhydramnios, Splenomegaly, Pancreatic lymphangiectasis, Pulmonary lymphangiectas...	ORPHA:1655
Arthrogryposis, Cleft Palate, Craniosynostosis, And Impaired Intellectual Development	Nonimmune hydrops fetalis	OMIM:618265
Mitochondrial Trifunctional Protein Deficiency 1	Abnormality of the amniotic fluid, Hydrops fetalis	OMIM:609015
Anemia, Congenital Dyserythropoietic, Type Ia	Splenomegaly, Hydrops fetalis	OMIM:224120
Dyssegmental Dysplasia, Silverman-Handmaker Type	Single umbilical artery, Hydrops fetalis, Increased placental thickness	ORPHA:1865
Greenberg Dysplasia	Nonimmune hydrops fetalis, Polyhydramnios, Echogenic fetal bowel, Large placenta, Increased nucha...	OMIM:215140
Cardiomyopathy, Familial Hypertrophic, 27	Nonimmune hydrops fetalis	OMIM:618052
Immunodeficiency 22	Pericarditis, Ascites, Capillary leak	OMIM:615758
Osteogenesis Imperfecta, Type Ii	Premature birth, Nonimmune hydrops fetalis	OMIM:166210
Familial Mediterranean Fever	Pericarditis, Myocardial infarction, Splenomegaly, Vasculitis, Pedal edema, Lymphadenopathy, Arrh...	ORPHA:342
Short-Rib Thoracic Dysplasia 7 With Or Without Polydactyly	Ascites, Hydrops fetalis	OMIM:614091
Alveolar Capillary Dysplasia With Misalignment Of Pulmonary Veins	Thickened nuchal skin fold, Nonimmune hydrops fetalis, Polyhydramnios, Asplenia, Pulmonary artery...	OMIM:265380
Fibrochondrogenesis 1	Stillbirth, Hydrops fetalis	OMIM:228520
Crimean-Congo Hemorrhagic Fever	Bundle branch block, Abnormal left ventricular function, Internal hemorrhage, Hepatomegaly, Peric...	ORPHA:99827
Gm1 Gangliosidosis Type 1	Cherry red spot of the macula, Hydrops fetalis, Abnormal placenta morphology, Hepatosplenomegaly	ORPHA:79255
Mitochondrial Dna Depletion Syndrome 3 (Hepatocerebral Type)	Splenomegaly, Ascites, Portal hypertension, Hepatomegaly	OMIM:251880
Kasabach-Merritt Syndrome	Abnormal lymphatic vessel morphology	ORPHA:2330
Adams-Oliver Syndrome	Gastrointestinal hemorrhage, Pulmonary arterial hypertension, Ascites, Portal hypertension	ORPHA:974
Hereditary Elliptocytosis	Splenomegaly, Hydrops fetalis	ORPHA:288
Kanzaki Disease	Lacunar stroke, Telangiectasia of the oral mucosa, Lip telangiectasia, Lymphedema	OMIM:609242
Cerebellar Ataxia, Deafness, And Narcolepsy, Autosomal Dominant	Predominantly lower limb lymphedema	OMIM:604121
S-Adenosylhomocysteine Hydrolase Deficiency	Hydrops fetalis	ORPHA:88618
Oculoectodermal Syndrome	Hypertrophic cardiomyopathy, Transient ischemic attack, Lymphedema	OMIM:600268
Gallbladder Neuroendocrine Tumor	Ascites, Chronic noninfectious lymphadenopathy	ORPHA:100086
Ogden Syndrome	Lymphedema, Ventricular tachycardia, Oligohydramnios, Premature ventricular contraction, Torsade ...	OMIM:300855
Microcephaly-Lymphedema-Chorioretinopathy Syndrome	Pleural effusion, Chylothorax, Edema, Lymphedema	ORPHA:2526
Granulomatous Disease, Chronic, X-Linked	Hepatomegaly, Splenomegaly, Lymphadenitis, Lymphadenopathy, Pleural effusion, Ascites	OMIM:306400
Macrothrombocytopenia-Lymphedema-Developmental Delay-Facial Dysmorphism-Camptodactyly Syndrome	Abnormality of the lymphatic system, Lymphedema	ORPHA:487796
Wolcott-Rallison Syndrome	Hepatomegaly, Ascites, Dehydration	ORPHA:1667
Spondylodysplastic Ehlers-Danlos Syndrome	Aortic valve stenosis, Pulmonic stenosis, Lymphedema	ORPHA:536471
Anemia, Congenital Dyserythropoietic, Type Iv	Splenomegaly, Hydrops fetalis, Hepatosplenomegaly	OMIM:613673
Mucopolysaccharidosis, Type Vii	Splenomegaly, Hydrops fetalis	OMIM:253220
Atresia Of Urethra	Pulmonary insufficiency, Ascites, Oligohydramnios	ORPHA:105
Congenital Disorder Of Glycosylation, Type Ia	Nonimmune hydrops fetalis, Edema, Pericardial effusion, Stroke-like episode, Abnormality of the a...	OMIM:212065
Acrocephalopolydactylous Dysplasia	Hepatomegaly, Ascites, Polysplenia	OMIM:200995
Blomstrand Lethal Chondrodysplasia	Premature birth, Hydrops fetalis, Polyhydramnios, Coarctation of aorta	ORPHA:50945
Immunodeficiency 87 And Autoimmunity	Hepatomegaly, Cervical lymphadenopathy, Dilated cardiomyopathy, Hypertension, Anasarca, Third deg...	OMIM:619573
Congenital Myopathy 22B, Severe Fetal	Decreased fetal movement, Nonimmune hydrops fetalis, Polyhydramnios, Breech presentation, Pleural...	OMIM:620369
Alg9-Cdg	Thickened nuchal skin fold, Decreased fetal movement, Pericardial effusion, Hydrops fetalis, Abno...	ORPHA:79328
Schneckenbecken Dysplasia	Polyhydramnios, Lymphedema	ORPHA:3144
Perlman Syndrome	Ascites, Polyhydramnios, Visceromegaly, Edema	OMIM:267000
Mycophenolate Mofetil Embryopathy	Hydrops fetalis, Coarctation of aorta	ORPHA:268249
Mgat2-Cdg	Patent ductus arteriosus, Hydrops fetalis	ORPHA:79329
Spondyloocular Syndrome	Lymphedema	OMIM:605822
Lysosomal Acid Lipase Deficiency	Hypersplenism, Hypovolemia, Dehydration, Hepatosplenomegaly, Hypotension, Pulmonary arterial hype...	ORPHA:275761
Bartter Syndrome, Type 4A, Neonatal, With Sensorineural Deafness	Fetal polyuria, Premature birth, Polyhydramnios, Edema, Hydrops fetalis	OMIM:602522
Short-Rib Thoracic Dysplasia 12	Hepatomegaly, Polyhydramnios, Edema, Splenomegaly, Ascites	OMIM:269860
Tyrosinemia, Type I	Gastrointestinal hemorrhage, Hepatomegaly, Splenomegaly, Melena, Hypertrophic cardiomyopathy, Asc...	OMIM:276700
Caroli Disease	Splenomegaly, Ascites, Portal hypertension, Hepatomegaly	ORPHA:53035
Peripheral Primitive Neuroectodermal Tumor	Ascites, Pelvic mass	ORPHA:370348
Costello Syndrome	Lymphangiectasis, Premature birth, Polyhydramnios	OMIM:218040
Multiple Congenital Anomalies-Hypotonia-Seizures Syndrome 2	Bilateral fetal pyelectasis, Polyhydramnios, Breech presentation, Patent ductus arteriosus, Hydro...	OMIM:300868
Methylmalonic Acidemia With Homocystinuria, Type Cblc	Stroke, Subdural hemorrhage, Hydrops fetalis, Dehydration	ORPHA:79282
Functioning Gonadotropic Adenoma	Ascites	ORPHA:91348
Xfe Progeroid Syndrome	Hypertension, Ascites	OMIM:610965
Osteopetrosis, Autosomal Recessive 5	Hepatomegaly, Splenomegaly, Ascites, Hepatosplenomegaly	OMIM:259720
Intrahepatic Cholestasis Of Pregnancy	Ascites	ORPHA:69665
Mitochondrial Dna Depletion Syndrome 15 (Hepatocerebral Type)	Congestive heart failure, Ascites, Polyhydramnios	OMIM:617156
Senior-Boichis Syndrome	Hypertension, Ascites, Portal hypertension, Hepatosplenomegaly	ORPHA:84081
Autoimmune Lymphoproliferative Syndrome	Chronic noninfectious lymphadenopathy, Hypersplenism, Splenomegaly, Vasculitis, Hydrops fetalis, ...	ORPHA:3261
Gaucher Disease Type 3	Pericardial effusion, Splenomegaly, Hydrops fetalis	ORPHA:77261
Fetal Akinesia Deformation Sequence 1	Decreased fetal movement, Premature birth, Nonimmune hydrops fetalis, Polyhydramnios, Fetal akine...	OMIM:208150
Grfoma	Gastrointestinal hemorrhage, Hepatomegaly, Neoplasm of the thymus, Abnormal abdomen morphology, A...	ORPHA:97261
Primary Sclerosing Cholangitis	Hepatomegaly, Spider hemangioma, Portal hypertension, Splenomegaly, Congestive heart failure, Hep...	ORPHA:171
Cardiac Valvular Dysplasia 1	Edema, Arteria lusoria, Hydrops fetalis, Left aortic arch with cervical origin of the right subcl...	OMIM:212093
Generalized Arterial Calcification Of Infancy	Medial calcification of large arteries, Transient ischemic attack, Coronary artery calcification,...	ORPHA:51608
Mitchell-Riley Syndrome	Ascites	OMIM:615710
Proteus Syndrome	Thymus hyperplasia, Sudden cardiac death, Lymphedema, Neoplasm of the thymus, Splenomegaly, Pulmo...	ORPHA:744
Autosomal Dominant Cerebellar Ataxia-Deafness-Narcolepsy Syndrome	Predominantly lower limb lymphedema	ORPHA:314404
Multiple Pterygium Syndrome, Escobar Variant	Decreased fetal movement, Hydrops fetalis	OMIM:265000
Short-Rib Thoracic Dysplasia 14 With Polydactyly	Hydrops fetalis, Polyhydramnios	OMIM:616546
Wilson Disease	Hepatomegaly, Edema, Splenomegaly, Pedal edema, Ascites	OMIM:277900
Primary Biliary Cholangitis	Orthostatic hypotension, Ascites, Portal hypertension	ORPHA:186
Cranioectodermal Dysplasia 2	Polyhydramnios, Splenomegaly, Patent ductus arteriosus, Hydrops fetalis, Polysplenia	OMIM:613610
Cutis Laxa, Autosomal Recessive, Type Ic	Periorbital edema, Ascites, Hypoplasia of the thymus, Accessory spleen	OMIM:613177
Neurodevelopmental Disorder With Epilepsy And Hemochromatosis	Splenomegaly, Ascites, Hepatomegaly	OMIM:301072
Noonan Syndrome 1	Hypertrophic cardiomyopathy, Chylothorax, Pulmonic stenosis, Lymphedema	OMIM:163950
Ppoma	Gastrointestinal hemorrhage, Hepatomegaly, Ascites, Abnormal abdomen morphology	ORPHA:97278
Fumarase Deficiency	Ascites, Polyhydramnios	OMIM:606812
Pearson Syndrome	Splenomegaly, Hydrops fetalis, Dehydration, Corneal stromal edema, Hypoplastic spleen	ORPHA:699
Monosomy 22Q13.3	Palpebral edema, Lymphedema	ORPHA:48652
Niemann-Pick Disease Type C	Fetal ascites, Bone-marrow foam cells, Splenomegaly, Hydrops fetalis, Hepatosplenomegaly, Foam ce...	ORPHA:646
Turner Syndrome Due To Structural X Chromosome Anomalies	Prolonged QT interval, Hypertension, Myocardial infarction, Lymphedema	ORPHA:99413
Turner Syndrome	Prolonged QT interval, Hypertension, Myocardial infarction, Lymphedema	ORPHA:881
Mosaic Monosomy X	Prolonged QT interval, Hypertension, Myocardial infarction, Lymphedema	ORPHA:99228
Monosomy X	Prolonged QT interval, Hypertension, Myocardial infarction, Lymphedema	ORPHA:99226
Vipoma	Hepatomegaly, Abnormal abdomen morphology, Dehydration, Hematochezia, Ascites	ORPHA:97282
Mosaic Variegated Aneuploidy Syndrome	Aortic regurgitation, Increased nuchal translucency, Ascites, Polyhydramnios	ORPHA:1052
Autosomal Recessive Polycystic Kidney Disease	Gastrointestinal hemorrhage, Portal hypertension, Hypersplenism, Splenomegaly, Hepatosplenomegaly...	ORPHA:731
Pearson Marrow-Pancreas Syndrome	Hydrops fetalis, Dehydration	OMIM:557000
Somatostatinoma	Gastrointestinal hemorrhage, Hepatomegaly, Ascites, Abnormal abdomen morphology	ORPHA:97283
Short-Rib Thoracic Dysplasia 6 With Or Without Polydactyly	Hydrops fetalis	OMIM:263520
Hepatoerythropoietic Porphyria	Splenomegaly, Abnormality of the amniotic fluid, Nonimmune hydrops fetalis, Edema	ORPHA:95159
Phocomelia, Schinzel Type	Hydrops fetalis	ORPHA:2879
Cutis Marmorata Telangiectatica Congenita	Ascites, Telangiectasia of the skin	ORPHA:1556
Glucagonoma	Gastrointestinal hemorrhage, Hepatomegaly, Ascites, Abnormal abdomen morphology	ORPHA:97280
Mitochondrial Dna Depletion Syndrome 6 (Hepatocerebral Type)	Hepatomegaly, Ascites	OMIM:256810
Yunis-Varon Syndrome	Polyhydramnios, Increased nuchal translucency, Hydrops fetalis, Renal artery stenosis, Tetralogy ...	ORPHA:3472
Mitochondrial Dna Depletion Syndrome 4A (Alpers Type)	Hepatomegaly, Anasarca, Ascites	OMIM:203700
Gaucher Disease	Splenomegaly, Cherry red spot of the macula, Hydrops fetalis	ORPHA:355
Rajab Interstitial Lung Disease With Brain Calcifications 1	Anasarca, Ascites, Portal hypertension, Oligohydramnios	OMIM:613658
Congenital Erythropoietic Porphyria	Splenomegaly, Abnormality of the amniotic fluid, Nonimmune hydrops fetalis, Edema	ORPHA:79277
Diamond-Blackfan Anemia	Radial artery aplasia, Nonimmune hydrops fetalis, Coarctation of aorta	ORPHA:124
Biliary, Renal, Neurologic, And Skeletal Syndrome	Aortic regurgitation, Hepatomegaly, Tricuspid regurgitation, Left-to-right shunt, Cardiac arrest,...	OMIM:619534
Liver Disease, Severe Congenital	Hepatomegaly, Splenomegaly, Abnormal left ventricular function, Ascites, Systolic heart murmur, P...	OMIM:619991
Pmm2-Cdg	Pericarditis, Angina pectoris, Lymphedema, Pericardial effusion, Intracranial hemorrhage, Anasarc...	ORPHA:79318
Johanson-Blizzard Syndrome	Hepatomegaly, Portal hypertension, Splenomegaly, Dilated cardiomyopathy, Anasarca, Ascites, Gener...	OMIM:243800
Chronic Graft Versus Host Disease	Pleural effusion, Ascites, Xerostomia	ORPHA:99921
Yunis-Varon Syndrome	Tetralogy of Fallot, Premature birth, Hydrops fetalis, Polyhydramnios	OMIM:216340
Short Rib-Polydactyly Syndrome, Verma-Naumoff Type	Hydrops fetalis	ORPHA:93271
Tuberous Sclerosis 1	Pulmonary lymphangiomyomatosis	OMIM:191100
Tuberous Sclerosis 2	Pulmonary lymphangiomyomatosis	OMIM:613254
Tuberous Sclerosis Complex	Aortic aneurysm, Pulmonary lymphangiomyomatosis	ORPHA:805

Histopathology

Summary table of phenotypes displayed during the Histopathology procedure which are considered significant. Full histopathology data table, including submitted images, can be accessed by clicking any row in this table.

There is no histopathology data for Vegfc

IMPC related publications

The table below lists publications which used either products generated by the IMPC or data produced by the phenotyping efforts of the IMPC. These publications have also been associated to Vegfc.

No publications found that use IMPC mice or data for Vegfc.

Order Mouse and ES Cells

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MGI Allele	Allele Type	Produced
Vegfc^{tm1e(EUCOMM)Hmgu}	Targeted, non-conditional allele	ES Cells
Vegfc^em1(IMPC)Mbp	Exon Deletion	Mice
Vegfc^{tm1a(EUCOMM)Hmgu}	KO first allele (reporter-tagged insertion with conditional potential)	Targeting vectors, ES Cells

Sequence

Guides

Sequence	Guide sequence	pam	chr	start	stop	strand	Genome build	gRNA Concentration	Truncated Guide	Reversed	Sanger service	Guide format	Guide source

Nucleases

Nuclease type	Nuclease class

Genotype primers

Sequence	Name

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