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Genes Phenotypes Help, News, Blog

Gene: Matn1 MGI:106591

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Gene Summary

Name:
matrilin 1, cartilage matrix protein
Synonyms:
CMP,  Crtm,  matrilin-1,  Mat1

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IMPC Data Collections

  • No Body Weight Data
  • No Embryo Imaging Data
  • No Viability Data

IMPC Phenotype Summary

Significant
Not Significant
Not tested

View all our phenotype data below

Phenotypes

The IMPC applies a panel of phenotyping screens to characterise single-gene knockout mice by comparison to wild types. Click on the different tabs to visualise significant phenotypes identified by the IMPC, as well as all data that was measured.

Phenotype System Allele Zyg Sex Life Stage P Value
decreased body weight Matn1tm1Goe HET Early adult 9.01×10-05

Download data as:  TSV  XLS

Select physiological systems to view:
Viewing: all phenotypes
Select physiological systems to view:
Viewing: all phenotypes

lacZ Expression

Expression data not available

Associated Images

Images submitted by IMPC centres for a selection of procedures. Each set of images is available to view in our image comparator.

Legacy Phenotype Associated Images
Matn1tm1Goe
WT, Female, WTSI
Matn1tm1Goe
knee, HOM, Female, WTSI
Matn1tm1Goe
HOM, Male, WTSI
Matn1tm1Goe
HOM, Female, WTSI
Matn1tm1Goe
WT, Female, WTSI

View all 182 images

Matn1tm1Goe
tail skin, WT, Female, WTSI
Matn1tm1Goe
tail skin, WT, Female, WTSI
Matn1tm1Goe
tail skin, HOM, Female, WTSI
Matn1tm1Goe
tail skin, HOM, Female, WTSI
Matn1tm1Goe
tail skin, WT, Female, WTSI

View all 6 images

Human diseases caused by Matn1 mutations

The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.

Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.

No human diseases associated to this gene by orthology or annotation.
No human diseases associated to this gene by phenotypic similarity.

Histopathology

Summary table of phenotypes displayed during the Histopathology procedure which are considered significant. Full histopathology data table, including submitted images, can be accessed by clicking any row in this table.

There is no histopathology data for Matn1

IMPC related publications

The table below lists publications which used either products generated by the IMPC or data produced by the phenotyping efforts of the IMPC. These publications have also been associated to Matn1.

There are 2 publications which use IMPC produced mice or data.

Title Journal IMPC Allele PubMed ID
Large-scale neuroanatomical study uncovers 198 gene associations in mouse brain morphogenesis. Nature communications (August 2019) Matn1tm1Goe PMC6671969
Mouse screen reveals multiple new genes underlying mouse and human hearing loss. PLoS biology (April 2019) Matn1tm1Goe PMC6459510

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.

MGI Allele Allele Type Produced
Matn1tm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells

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