Gene: Cxcr2

Name chemokine (C-X-C motif) receptor 2

Synonyms
  • Il8rb
  • IL-8Rh
  • Gpcr16
  • CD128
  • Cmkar2
  • IL8RA
  • IL-8rb

Status ES CellsMice
tm1a
phenotype data available

Links MGI:105303   Ensembl Gene   Ensembl Orthologs

Viability Homozygous - Viable

Phenotype associations for Cxcr2

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Cxcr2 data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
increased anti-nuclear antigen antibody level Cxcr2tm1a(EUCOMM)Wtsi HOM Female Male postnatal 0.0
increased circulating calcium level Cxcr2tm1a(EUCOMM)Wtsi HOM Female postnatal 6.78E-7
increased circulating creatinine level Cxcr2tm1a(EUCOMM)Wtsi HET Female postnatal 8.17E-7
increased circulating magnesium level Cxcr2tm1a(EUCOMM)Wtsi HET Female Male postnatal 2.9E-5
increased circulating total protein level Cxcr2tm1a(EUCOMM)Wtsi HOM Female Male postnatal 3.4E-5

Download data as: TSV XLS



Expression

Expression data not available

Associated Images

Associated Images
  • Anti-nuclear antibody assay
    19 Images
  • X-ray: XRay Images Lateral Orientation
    50 Images
  • X-ray: XRay Images Skull Lateral Orientation
    25 Images
  • X-ray: XRay Images Dorso Ventral
    76 Images
  • X-ray: XRay Images Forepaw
    26 Images
  • X-ray: XRay Images Skull Dorso Ventral Orientation
    25 Images
Legacy Phenotype Associated Images
Xray (126)
  • Cxcr2tm1a(EUCOMM)Wtsi
    HOM, Male, WTSI
  • Cxcr2tm1a(EUCOMM)Wtsi
    HOM, Male, WTSI
  • Cxcr2tm1a(EUCOMM)Wtsi
    HOM, Male, WTSI
  • Cxcr2tm1a(EUCOMM)Wtsi
    HOM, Male, WTSI
  • Cxcr2tm1a(EUCOMM)Wtsi
    HOM, Male, WTSI

show all 126 images

Dysmorphology (6)
  • Cxcr2tm1a(EUCOMM)Wtsi
    HEAD, abnormal snout morphology, asymmetric snout, HET, Male, WTSI
  • Cxcr2tm1a(EUCOMM)Wtsi
    HEAD, abnormal snout morphology, upturned snout, HET, Male, WTSI
  • Cxcr2tm1a(EUCOMM)Wtsi
    HEAD, abnormal snout morphology, asymmetric snout, malocclusion, HET, Male, WTSI
  • Cxcr2tm1a(EUCOMM)Wtsi
    HEAD, abnormal snout morphology, upturned snout, HET, Male, WTSI
  • Cxcr2tm1a(EUCOMM)Wtsi
    HEAD, abnormal snout morphology, asymmetric snout, HET, Male, WTSI

show all 6 images

Eye Morphology (5)
  • Cxcr2tm1a(EUCOMM)Wtsi
    abnormal cornea morphology, HET, Female, WTSI
  • Cxcr2tm1a(EUCOMM)Wtsi
    abnormal retinal pigmentation, HOM, Male, WTSI
  • Cxcr2tm1a(EUCOMM)Wtsi
    abnormal retinal pigmentation, HOM, Male, WTSI
  • Cxcr2tm1a(EUCOMM)Wtsi
    abnormal retinal pigmentation, HOM, Male, WTSI
  • Cxcr2tm1a(EUCOMM)Wtsi
    abnormal pupil morphology, HET, Female, WTSI

Disease Models

No associations by disease annotation and gene orthology found.

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Cxcr2tm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene