Gene: Nin

Name ninein

Synonyms 3110068G20Rik

Status ES CellsMice
tm1a
Mice
tm1b
phenotype data available

Links MGI:105108   Ensembl Gene   Ensembl Orthologs

Viability Homozygous - Viable

Phenotype associations for Nin

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Nin data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
decreased prepulse inhibition Nintm1b(EUCOMM)Hmgu HOM Female Male postnatal 5.03E-17
prolonged ST segment Nintm1b(EUCOMM)Hmgu HOM Female Male postnatal 9.25E-16
prolonged QT interval Nintm1b(EUCOMM)Hmgu HOM Female Male postnatal 4.69E-14
decreased startle reflex Nintm1b(EUCOMM)Hmgu HOM Female Male postnatal 5.27E-12
cardiovascular system phenotype Nintm1b(EUCOMM)Hmgu HOM Female Male postnatal 5.03E-7
increased or absent threshold for auditory brainstem response Nintm1b(EUCOMM)Hmgu HOM Female Male postnatal 1.5E-6

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 4 Yes (2/354)
Aorta 4 Yes (2/530) (2/6)
Bone 4 Yes (1/515) (2/6)
Brain 4 Yes (8/530) (6/6)
Brainstem 4 No (5/530) (6/6)
Brown adipose tissue 4 No
Cartilage tissue 4 No (1/530) (2/6)
Cecum 4 Yes (1/325) (6/6)
Cerebellum 4 No (6/530) (6/6)
Cerebral cortex 4 No (6/530) (6/6)
Chest bone 4 Yes (6/6)
Colon 4 No (1/99) (6/6)
Cranium 4 No
Diaphragm 4 Yes
Duodenum 4 Yes (1/99) (6/6)
Epididymis 4 Yes (1/103)
Esophagus 4 Yes (1/354) (2/6)
Eye 4 No (1/530)
Gall bladder 4 Yes (2/6)
Gonadal fat pad 4 No
Harderian gland 4 Yes
Heart 4 Yes (4/530) (2/6)
Hindlimb 4 Yes (2/6)
Hippocampus 4 No (7/530) (6/6)
Hypothalamus 4 No (5/529) (6/6)
Ileum 4 Yes (1/99) (6/6)
Jejunum 4 Yes (1/99) (6/6)
Kidney 4 Yes (13/530) (6/6)
Large intestine 4 Yes (7/530) (6/6)
Liver 4 Yes
Lower urinary tract 4 No (3/530) (5/6)
Lung 4 Yes (4/530) (6/6)
Lymph node 4 Yes (2/530)
Main olfactory bulb 4 Yes (6/6)
Mammary gland 4 Yes
Mesenteric lymph node 4 Yes
Mesenteric adipose tissue 4 Yes
Midbrain 4 No (6/6)
Olfactory lobe 4 No (3/354) (6/6)
Oral epithelium 4 No
Ovary 4 Yes (1/530) (2/6)
Oviduct 4 Yes (1/530) (3/6)
Pancreas 4 No (2/530)
Parathyroid gland 4 Yes (2/516) (5/6)
Parotid gland 4 Yes
Penis 4 Yes (3/6)
Peripheral nervous system 4 No (4/530) (2/6)
Peyer's patch 4 No (1/354)
Pituitary gland 4 Yes (2/530) (6/6)
Prostate gland 4 Yes (3/530)
Quadriceps 4 Yes
Sciatic nerve 4 Yes (2/6)
Skeletal muscle 4 No
Skin 4 Yes (2/530) (2/6)
Small intestine 4 No (5/530) (6/6)
Spinal cord 4 Yes (5/530) (6/6)
Spleen 4 Yes (3/530)
Stomach 4 Yes (5/530) (6/6)
Stomach pyloric region 4 No
Striatum 4 No (6/530) (6/6)
Sublingual gland 4 Yes
Submandibular gland 4 Yes
Testis 4 Yes (7/530) (3/6)
Thalamus 4 No (6/6)
Thymus 4 Yes (1/530) (2/6)
Thyroid gland 4 Yes (11/530)
Tongue 4 Yes (2/6)
Trachea 4 Yes (5/530) (6/6)
Trigeminal V nerve 4 Yes (6/6)
Urinary bladder 4 Yes (5/6)
Uterus 4 Yes (1/530) (3/6)
Vagina 4 Yes (1/6)
Vas deferens 4 No (1/331)
Vascular system 4 No (1/354) (2/6)
Vesicular gland 4 Yes
White adipose tissue 4 Yes
Expression in Anatomogram

Tissues/organs lacZ+ expression

    respiratory system
    endocrine system
    limb
    digestive system
    cardiovascular system
    set of connective tissues
    reproductive system
    musculoskeletal system
    trunk
    postnatal mouse
    nervous system
    sensory organ
    immune system
    integumental system
    urinary system
No expression image was found for this adult tab

 Expression    No Expression    No Tissue Available    Ambiguous  

Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 9 (5/413) (11/11)
Ear 9
Embryo 9 (11/11)
Eye 9 (2/11)
Foot 9
Forearm 9 (9/11)
Forebrain 9
Forelimb 9 (9/11)
Hand 9
Head 9 (4/413) (11/11)
Heart 9
Hindbrain 9 (5/413) (11/11)
Hindlimb 9 (9/11)
Liver 9
Lower leg 9 (4/11)
Lung 9
Mandibular process 9
Maxillary process 9
Midbrain 9 (2/11)
Oral cavity 9
Skin 9
Tail 9 (11/11)
Tail somite 9
Upper arm 9 (9/11)
Upper leg 9 (9/11)
  • head(5)
    Eye expression
    EMAPA:16198 eye
  • limb(19)
    Forelimb expression
    EMAPA:17412 forelimb


Associated Images

Associated Images
  • Adult LacZ: LacZ Images Wholemount
    377 Images
  • Embryo LacZ: LacZ images wholemount
    223 Images
  • X-ray: XRay Images Dorso Ventral
    10 Images
  • X-ray: XRay Images Lateral Orientation
    10 Images
  • Eye Morphology: Images Ophthalmoscopy
    1 Images
  • Eye Morphology: Images Slit Lamp
    2 Images

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse
Nintm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene
Nintm1b(EUCOMM)Hmgu Reporter-tagged deletion allele (post-Cre)
Vector
Gene