Gene: Sik1

Order

Name salt inducible kinase 1

Synonyms
  • Snf1lk
  • Msk

Status ES CellsMice
tm1
Mice
tm1.1
phenotype data available

Links MGI:104754    Ensembl Gene    Ensembl Orthologs    My Genes   

Viability Homozygous - Viable

Phenotype associations for Sik1

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Sik1 data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
increased heart weight Sik1tm1.1(KOMP)Vlcg HOM Male postnatal 3.64E-11
decreased body length Sik1tm1.1(KOMP)Vlcg HOM Female postnatal 8.98E-9
decreased total body fat amount Sik1tm1.1(KOMP)Vlcg HOM Female Male postnatal 1.12E-8
increased lean body mass Sik1tm1.1(KOMP)Vlcg HOM Female Male postnatal 2.2E-7
increased bone mineral content Sik1tm1.1(KOMP)Vlcg HOM Female Male postnatal 7.38E-7
decreased lean body mass Sik1tm1.1(KOMP)Vlcg HOM Female postnatal 6.18E-6
improved glucose tolerance Sik1tm1.1(KOMP)Vlcg HOM Male postnatal 2.31E-5

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 4 No (2/415) (4/4)
Aorta 4 No (3/4)
Blood 4 No
Bone marrow 4 No
Brain 4 No (2/4)
Brainstem 4 No
Brown adipose tissue 4 No (4/4)
Cartilage tissue 4 No
Cecum 4 No (12/383) (4/4)
Cerebellum 4 No (4/4)
Cerebral cortex 4 No
Chest bone 4 No (2/4)
Colon 4 No (12/127) (4/4)
Diaphragm 4 No (4/4)
Duodenum 4 No (2/127) (3/4)
Epididymis 4 No (18/134) (2/4)
Esophagus 4 No (7/415) (4/4)
Eye 4 No (4/4)
Gall bladder 4 No (2/4)
Gonadal fat pad 4 No (2/4)
Harderian gland 4 No (4/4)
Heart 4 No
Hindlimb 4 No
Hippocampus 4 No
Hypothalamus 4 No
Ileum 4 No (14/127) (3/4)
Jejunum 4 No (6/127) (3/4)
Kidney 4 No (18/584) (4/4)
Large intestine 4 No (10/584)
Liver 4 No (3/4)
Lower urinary tract 4 No
Lung 4 No (4/4)
Lymph node 4 No
Mammary gland 4 No
Mesenteric lymph node 4 No (3/4)
Mesenteric adipose tissue 4 No (3/4)
Midbrain 4 No (4/4)
Olfactory lobe 4 No (4/4)
Ovary 4 No (1/584) (2/4)
Oviduct 4 No (2/4)
Pancreas 4 No (5/584) (3/4)
Parathyroid gland 4 No (2/4)
Parotid gland 4 No (1/4)
Penis 4 No (1/4)
Peripheral nervous system 4 No
Peyer's patch 4 No
Pituitary gland 4 No (4/4)
Prostate gland 4 No (12/584) (2/4)
Quadriceps 4 No (4/4)
Sciatic nerve 4 No
Skeletal muscle 4 No
Skin 4 No (4/4)
Small intestine 4 No (9/584)
Spinal cord 4 No (3/4)
Spleen 4 No (2/584) (4/4)
Stomach 4 No (12/584) (4/4)
Stomach pyloric region 4 No
Striatum 4 No
Sublingual gland 4 No (2/4)
Submandibular gland 4 No (2/132) (2/4)
Testis 4 No (2/584) (2/4)
Thymus 4 No (4/4)
Thyroid gland 4 No (15/584) (3/4)
Tongue 4 No (5/127) (4/4)
Trachea 4 No (4/4)
Trigeminal V nerve 4 No (1/4)
Urinary bladder 4 No (4/4)
Uterus 4 No (2/4)
Vagina 4 No (1/4)
Vas deferens 4 No (15/388) (2/4)
Vascular system 4 No
Vesicular gland 4 No (2/4)
White adipose tissue 4 No
Expression in Anatomogram

Tissues/organs lacZ+ expression

    endocrine system respiratory system digestive system cardiovascular system set of connective tissues reproductive system adipose tissue musculoskeletal system trunk postnatal mouse nervous system sensory organ immune system exocrine system integumental system urinary system
No expression image was found for this adult tab
No expression data was found for this embryo tab


Associated Images

Associated Images
  • X-ray: XRay Images Dorso Ventral
    42 Images
  • X-ray: XRay Images Lateral Orientation
    20 Images

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Sik1tm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette)
Vector
Gene
Sik1tm1.1(KOMP)Vlcg Reporter-tagged deletion allele (post Cre, with no selection cassette)
Vector
Gene
Fixed Tissue
Sik1tm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene