Gene: Fnta

Order

Name farnesyltransferase, CAAX box, alpha

Synonyms FTA

Status ES CellsMice
tm1a
Mice
tm1b
phenotype data available

Links MGI:104683    Ensembl Gene    Ensembl Orthologs    My Genes   

Viability Homozygous - Lethal

Phenotype associations for Fnta

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Fnta data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
embryonic lethality prior to organogenesis Fntatm1b(KOMP)Wtsi HOM Female Male embryonic day 9.5 0.0
embryonic lethality prior to tooth bud stage Fntatm1b(KOMP)Wtsi HOM Female Male embryonic day 12.5 0.0
preweaning lethality, complete penetrance Fntatm1b(KOMP)Wtsi HOM Female Male n/a 0.0
decreased circulating serum albumin level Fntatm1b(KOMP)Wtsi HET Female Male postnatal 4.67E-5

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 5 No (2/415) (4/5)
Aorta 5 No (1/5)
Blood 3 No
Bone 2 No (2/2)
Bone marrow 3 No
Brain 5 No (3/5)
Brainstem 5 No (2/5)
Brown adipose tissue 5 No (2/5)
Cartilage tissue 5 No
Cecum 3 No (12/383) (2/3)
Cerebellum 5 No (4/5)
Cerebral cortex 5 No
Chest bone 3 No (1/3)
Colon 3 No (12/127) (2/3)
Diaphragm 3 No
Duodenum 3 No (2/127) (2/3)
Epididymis 3 No (18/134) (1/3)
Esophagus 5 No (7/415) (4/5)
Eye 5 No (2/5)
Gall bladder 3 No
Gonadal fat pad 3 No
Harderian gland 3 No (2/3)
Heart 5 No (2/5)
Hindlimb 3 No
Hippocampus 5 No
Hypothalamus 5 No
Ileum 3 No (14/127) (3/3)
Jejunum 3 No (6/127) (2/3)
Kidney 5 No (18/584) (4/5)
Large intestine 5 No (10/584) (2/5)
Liver 5 No (2/5)
Lower urinary tract 5 No
Lung 5 No (4/5)
Lymph node 5 No
Mammary gland 5 No (1/5)
Mesenteric lymph node 3 No
Mesenteric adipose tissue 3 No (1/3)
Midbrain 3 No (2/3)
Olfactory lobe 5 No (2/5)
Ovary 5 No (1/584) (2/5)
Oviduct 5 No (2/5)
Pancreas 5 No (5/584) (3/5)
Parathyroid gland 4 No (2/4)
Parotid gland 3 No (1/3)
Penis 3 No (1/3)
Peripheral nervous system 5 No
Peyer's patch 5 No
Pituitary gland 5 No (2/5)
Prostate gland 5 No (12/584) (2/5)
Quadriceps 3 No
Sciatic nerve 3 No (1/3)
Skeletal muscle 5 No
Skin 5 No (3/5)
Small intestine 5 No (9/584)
Spinal cord 5 No (4/5)
Spleen 5 No (2/584) (2/5)
Stomach 5 No (12/584) (4/5)
Stomach pyloric region 3 No
Striatum 5 No
Sublingual gland 3 No
Submandibular gland 3 No (2/132)
Testis 5 No (2/584) (1/5)
Thymus 5 No (3/5)
Thyroid gland 5 No (15/584) (3/5)
Tongue 3 No (5/127) (1/3)
Trachea 5 No (1/5)
Trigeminal V nerve 3 No (1/3)
Urinary bladder 5 No (4/5)
Uterus 5 No (2/5)
Vagina 3 No (1/3)
Vas deferens 3 No (15/388) (1/3)
Vascular system 5 No (2/5)
Vesicular gland 3 No (1/3)
White adipose tissue 5 No
Expression in Anatomogram

Tissues/organs lacZ+ expression

    endocrine system
    respiratory system
    limb
    digestive system
    cardiovascular system
    set of connective tissues
    reproductive system musculoskeletal system
    adipose tissue
    trunk
    postnatal mouse
    nervous system
    sensory organ
    immune system
    exocrine system
    integumental system
    urinary system
No expression image was found for this adult tab

 Expression    No Expression    No Tissue Available    Ambiguous  

Anatomy #HET Specimens WT Expr Mutant Expr Images
Axial skeleton 2 (1/51) (2/2)
Brain 7 (6/485) (2/7)
Central nervous system ganglion 2 (1/51) (2/2)
Ear 7 (1/485) (2/7)
Embryo 7 (1/485) (2/7)
Eye 7 (1/485) (2/7)
Foot 7 (1/485) (2/7)
Forebrain 7 (1/485) (2/7)
Forelimb 7 (1/485) (2/7)
Gut 2 (1/50) (2/2)
Hand 7 (1/485) (2/7)
Head 7 (5/485) (2/7)
Heart 7 (1/485) (2/7)
Hindbrain 7 (6/485) (2/7)
Hindlimb 7 (1/485) (2/7)
Liver 7 (1/485) (2/7)
Lung 7 (1/485) (2/7)
Mandibular process 7 (1/485) (2/7)
Maxillary process 7 (1/485) (2/7)
Midbrain 7 (1/485) (2/7)
Nose 2 (1/51) (2/2)
Oral cavity 7 (1/485) (2/7)
2 (7/25) (2/2)
Skeleton 2 (1/51) (2/2)
Skin 7 (1/485) (2/7)
Spinal cord 2 (1/50) (2/2)
Tail 7 (1/485) (2/7)
Tail somite 7 (1/485) (2/7)
Trachea 2 (1/50) (2/2)
Urinary system 2 (1/50) (2/2)


Associated Images

Associated Images
  • Embryo LacZ: LacZ images wholemount
    20 Images
  • Adult LacZ: LacZ Images Section
    26 Images
  • X-ray: XRay Images Lateral Orientation
    10 Images
  • X-ray: XRay Images Dorso Ventral
    10 Images

Disease Models

No associations by disease annotation and gene orthology found.

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Fntatm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene
Fntatm1b(KOMP)Wtsi Reporter-tagged deletion allele (post-Cre)
Vector
Gene
Fixed Tissue