Gene: Capzb

Name capping protein (actin filament) muscle Z-line, beta

Synonyms
  • Cappb1
  • 1700120C01Rik
  • CPB1
  • CPbeta1
  • CPbeta2
  • CPB2

Status ES CellsMice
tm1a
phenotype data available

Links MGI:104652   Ensembl Gene   Ensembl Orthologs

Viability Homozygous - Lethal

Phenotype associations for Capzb

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Capzb data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
preweaning lethality, complete penetrance Capzbtm1a(EUCOMM)Wtsi HOM Female Male n/a 0.0

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No
Aorta 2 No (1/562)
Blood vessel 2 No
Bone 2 No (1/539)
Brain 2 No (5/562) (2/2)
Brainstem 2 No (4/562)
Brown adipose tissue 2 No
Cartilage tissue 2 No (1/562)
Cerebellum 2 No (4/562)
Cerebral cortex 2 No (5/562)
Eye 2 No (1/562)
Gall bladder 2 No
Heart 2 No (3/562) (2/2)
Hippocampus 2 No (5/562)
Hypothalamus 2 No (4/562)
Kidney 2 No (19/562)
Large intestine 2 No (12/562)
Liver 2 No
Lower urinary tract 2 No (3/562)
Lung 2 No (3/562) (2/2)
Lymph node 2 No (1/562)
Mammary gland 2 No
Esophagus 2 No
Olfactory lobe 2 No
Ovary 2 No (1/562)
Oviduct 2 No (2/562) (1/2)
Pancreas 2 No (6/562)
Parathyroid gland 2 No (2/540)
Peripheral nervous system 2 No (3/562)
Peyer's patch 2 No
Pituitary gland 2 No (1/562)
Prostate gland 2 No (5/562)
Skeletal muscle tissue 2 No
Skin 2 No (1/562) (2/2)
Small intestine 2 No (11/562)
Spinal cord 2 No (3/562)
Spleen 2 No (4/562)
Stomach 2 No (9/562) (2/2)
Striatum 2 No (4/562)
Testis 2 No (3/562) (1/2)
Thymus 2 No
Thyroid gland 2 No (16/562) (1/2)
Trachea 2 No (3/562)
Uterus 2 No (2/562)
White adipose tissue 2 No
Expression in Anatomogram

Tissues/organs lacZ+ expression

    postnatal mouse respiratory system endocrine system digestive system cardiovascular system nervous system reproductive system integumental system trunk
No expression image was found for this adult tab
No expression data was found for this embryo tab


Secondary lacZ Expression Data
trunk (5)
  • Capzbtm1a(EUCOMM)Wtsi
    TESTIS, HET, Male, WTSI
  • Capzbtm1a(EUCOMM)Wtsi
    HEART, HET, Female, WTSI
  • Capzbtm1a(EUCOMM)Wtsi
    LUNG, HET, Female, WTSI
  • Capzbtm1a(EUCOMM)Wtsi
    STOMACH, HET, Female, WTSI
  • Capzbtm1a(EUCOMM)Wtsi
    OVIDUCT, HET, Female, WTSI
reproductive system (2)
  • Capzbtm1a(EUCOMM)Wtsi
    TESTIS, HET, Male, WTSI
  • Capzbtm1a(EUCOMM)Wtsi
    OVIDUCT, HET, Female, WTSI
cardiovascular system (1)
  • Capzbtm1a(EUCOMM)Wtsi
    HEART, HET, Female, WTSI
digestive system (1)
  • Capzbtm1a(EUCOMM)Wtsi
    STOMACH, HET, Female, WTSI
endocrine system (1)
  • Capzbtm1a(EUCOMM)Wtsi
    THYROID GLAND, HET, Male, WTSI
integumental system (1)
  • Capzbtm1a(EUCOMM)Wtsi
    SKIN, AURICLE, HET, Male, WTSI
nervous system (1)
  • Capzbtm1a(EUCOMM)Wtsi
    BRAIN, HET, Female, WTSI
respiratory system (1)
  • Capzbtm1a(EUCOMM)Wtsi
    LUNG, HET, Female, WTSI
sensory organ (1)
  • Capzbtm1a(EUCOMM)Wtsi
    SKIN, AURICLE, HET, Male, WTSI

Associated Images

Legacy Phenotype Associated Images
Xray (76)
  • Capzbtm1a(EUCOMM)Wtsi
    HEAD, WT, Female, WTSI
  • Capzbtm1a(EUCOMM)Wtsi
    TRUNK, WT, Female, WTSI
  • Capzbtm1a(EUCOMM)Wtsi
    HEAD, WT, Female, WTSI
  • Capzbtm1a(EUCOMM)Wtsi
    LOWER ARM, WT, Female, WTSI
  • Capzbtm1a(EUCOMM)Wtsi
    TRUNK, WT, Female, WTSI

show all 76 images

Skin Histopathology (3)
  • Capzbtm1a(EUCOMM)Wtsi
    FOOT DIGIT 4, HET, Female, WTSI
  • Capzbtm1a(EUCOMM)Wtsi
    FOOT DIGIT 4, HET, Female, WTSI
  • Capzbtm1a(EUCOMM)Wtsi
    FOOT DIGIT 4, HET, Female, WTSI
Eye Morphology (2)
  • Capzbtm1a(EUCOMM)Wtsi
    EYE, abnormal retinal pigmentation, HET, Male, WTSI
  • Capzbtm1a(EUCOMM)Wtsi
    EYE, abnormal retinal blood vessel pattern, HET, Male, WTSI

Disease Models

No associations by disease annotation and gene orthology found.

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Capzbtm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene