Gene: Cyp4b1

Order

Name cytochrome P450, family 4, subfamily b, polypeptide 1

Status ES CellsMice
tm1b
Mice
tm1a
phenotype data available

Links MGI:103225    Ensembl Gene    Ensembl Orthologs    My Genes   

Viability Homozygous - Viable

Phenotype associations for Cyp4b1

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Cyp4b1 data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
decreased blood urea nitrogen level Cyp4b1tm1b(KOMP)Wtsi HOM Female Male postnatal 7.03E-7
decreased circulating triglyceride level Cyp4b1tm1b(KOMP)Wtsi HOM Female Male postnatal 8.31E-7
hyperactivity Cyp4b1tm1b(KOMP)Wtsi HOM Female postnatal 4.54E-6
decreased mean platelet volume Cyp4b1tm1b(KOMP)Wtsi HOM Female Male postnatal 5.05E-5

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 1 No (5/393)
Aorta 1 No (1/562)
Blood 1 No
Bone 1 No (1/539)
Bone marrow 1 No
Brain 1 No (6/562)
Brainstem 1 No (4/562)
Brown adipose tissue 1 No
Cartilage tissue 1 No (1/562)
Cecum 1 No (1/355)
Cerebellum 1 No (4/562)
Cerebral cortex 1 No (5/562)
Chest bone 1 No
Colon 1 No (1/99)
Cranium 1 No
Diaphragm 1 No
Epididymis 1 No (4/106) (1/1)
Esophagus 1 No (2/393)
Eye 1 No (1/562)
Gall bladder 1 No
Harderian gland 1 No
Heart 1 No (3/562)
Hindlimb 1 No
Hippocampus 1 No (5/562)
Hypothalamus 1 No (4/562)
Kidney 1 No (20/562)
Large intestine 1 No (12/562)
Liver 1 No
Lower urinary tract 1 No (3/562)
Lung 1 No (3/562)
Lymph node 1 No (1/562)
Main olfactory bulb 1 No
Mammary gland 1 No
Mesenteric lymph node 1 No
Olfactory lobe 1 No (4/393)
Oral epithelium 1 No
Ovary 1 No (1/562)
Oviduct 1 No (2/562)
Pancreas 1 No (6/562)
Parathyroid gland 1 No (2/540)
Parotid gland 1 No
Penis 1 No
Peripheral nervous system 1 No (3/562)
Peyer's patch 1 No (1/393)
Pituitary gland 1 No (1/562)
Prostate gland 1 No (5/562)
Sciatic nerve 1 No
Skeletal muscle 1 No
Skin 1 No (1/562)
Small intestine 1 No (11/562)
Spinal cord 1 No (3/562)
Spleen 1 No (4/562)
Stomach 1 No (9/562)
Stomach pyloric region 1 No
Striatum 1 No (4/562)
Sublingual gland 1 No
Submandibular gland 1 No (1/104)
Testis 1 No (4/562)
Thymus 1 No
Thyroid gland 1 No (16/562)
Tongue 1 No
Trachea 1 No (3/562)
Trigeminal V nerve 1 No
Urinary bladder 1 No
Uterus 1 No (2/562)
Vagina 1 No
Vas deferens 1 No (1/360)
Vascular system 1 No (1/393)
Vesicular gland 1 No
White adipose tissue 1 No
Expression in Anatomogram

Tissues/organs lacZ+ expression

    postnatal mouse
    reproductive system
    trunk
No expression image was found for this adult tab
No expression data was found for this embryo tab


Associated Images

Associated Images
  • X-ray: XRay Images Lateral Orientation
    9 Images
  • X-ray: XRay Images Dorso Ventral
    9 Images
  • Adult LacZ: LacZ Images Wholemount
    1 Images

Disease Models

No associations by disease annotation and gene orthology found.

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Cyp4b1tm1b(KOMP)Wtsi Reporter-tagged deletion allele (post-Cre)
Vector
Gene
Cyp4b1tm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene