Gene: Scx

Order

Name scleraxis

Synonyms
  • Scl
  • bHLHa41

Status ES CellsMice
tm1
Mice
tm1.1
phenotype data available

Links MGI:102934    Ensembl Gene    Ensembl Orthologs    My Genes   

Viability Homozygous - Lethal

Phenotype associations for Scx

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Scx data for that phenotype.

Embryo Data: 3D Embryo Imaging
Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
preweaning lethality, complete penetrance Scxtm1.1(KOMP)Vlcg HOM Female Male n/a 0.0
decreased circulating insulin level Scxtm1.1(KOMP)Vlcg HET Female Male postnatal 6.76E-5

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No (2/415)
Aorta 2 No
Blood 2 No
Bone marrow 2 No
Brain 2 No
Brainstem 2 No
Brown adipose tissue 2 No
Cartilage tissue 2 No
Cecum 2 No (12/383)
Cerebellum 2 No
Cerebral cortex 2 No
Chest bone 2 No
Colon 2 No (12/127)
Diaphragm 2 No
Duodenum 2 No (2/127) (1/2)
Epididymis 2 No (18/134) (1/2)
Esophagus 2 No (7/415)
Eye 2 No
Gall bladder 2 No
Gonadal fat pad 2 No
Harderian gland 2 No
Heart 2 No
Hindlimb 2 No
Hippocampus 2 No
Hypothalamus 2 No
Ileum 2 No (14/127) (2/2)
Jejunum 2 No (6/127) (1/2)
Kidney 2 No (18/584)
Large intestine 2 No (10/584)
Liver 2 No
Lower urinary tract 2 No
Lung 2 No
Lymph node 2 No
Mammary gland 2 No
Mesenteric lymph node 2 No
Mesenteric adipose tissue 2 No
Midbrain 2 No
Olfactory lobe 2 No
Ovary 2 No (1/584)
Oviduct 2 No
Pancreas 2 No (5/584)
Parathyroid gland 2 No
Parotid gland 2 No
Penis 2 No
Peripheral nervous system 2 No
Peyer's patch 2 No
Pituitary gland 2 No
Prostate gland 2 No (12/584)
Quadriceps 2 No
Sciatic nerve 2 No
Skeletal muscle 2 No
Skin 2 No
Small intestine 2 No (9/584)
Spinal cord 2 No
Spleen 2 No (2/584)
Stomach 2 No (12/584)
Stomach pyloric region 2 No
Striatum 2 No
Sublingual gland 2 No
Submandibular gland 2 No (2/132)
Testis 2 No (2/584)
Thymus 2 No
Thyroid gland 2 No (15/584)
Tongue 2 No (5/127)
Trachea 2 No
Trigeminal V nerve 2 No
Urinary bladder 2 No
Uterus 2 No
Vagina 2 No
Vas deferens 2 No (15/388) (1/2)
Vascular system 2 No
Vesicular gland 2 No
White adipose tissue 2 No
Expression in Anatomogram

Tissues/organs lacZ+ expression

    postnatal mouse digestive system reproductive system trunk
No expression image was found for this adult tab

 Expression    No Expression    No Tissue Available    Ambiguous  

Anatomy #HET Specimens WT Expr Mutant Expr Images
Heart atrium 6 (1/47)
Axial skeleton 6 (1/51) (2/7)
Brain 6 (6/485) (1/7)
Central nervous system ganglion 6 (1/51)
Dorsal root ganglion 6 (1/47)
Ear 6 (1/485) (7/7)
Embryo 6 (1/485) (7/7)
Outer ear 6 (1/47) (1/7)
Eye 6 (1/485)
Foot 6 (1/485)
Forebrain 6 (1/485)
Forelimb 6 (1/485)
Fronto-nasal process 6 (1/48)
Gut 6 (1/50)
Hand 6 (1/485)
Head 6 (5/485)
Head mesenchyme 6 (1/47)
Heart 6 (1/485)
Heart ventricle 6 (1/47)
Hindbrain 6 (6/485)
Hindlimb 6 (1/485)
Inner ear 6 (1/46) (7/7)
Liver 6 (1/485) (1/7)
Lung 6 (1/485)
Mandibular process 6 (1/485) (1/7)
Maxillary process 6 (1/485)
Meckel's cartilage 6 (1/7)
Midbrain 6 (1/485)
Nasal septum 6 (1/47)
Nose 6 (1/51)
Notochord 6 (1/47)
Oral cavity 6 (1/485)
Outflow tract 6 (1/47)
Pericardium 6 (1/46)
Skeleton 6 (1/51) (7/7)
Skin 6 (1/485)
Spinal cord 6 (1/50) (1/7)
Tail 6 (1/485)
Tail somite 6 (1/485) (1/7)
Tongue 6 (1/46)
Trunk mesenchyme 6 (1/47) (1/7)
Vibrissa 6 (1/47)


Associated Images

Associated Images
  • X-ray: XRay Images Lateral Orientation
    20 Images
  • X-ray: XRay Images Dorso Ventral
    41 Images

Disease Models

No associations by disease annotation and gene orthology found.

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Scxtm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette)
Vector
Gene
Scxtm1.1(KOMP)Vlcg Reporter-tagged deletion allele (post Cre, with no selection cassette)
Vector
Gene
Fixed Tissue