Gene: Pdx1

Order

Name pancreatic and duodenal homeobox 1

Synonyms
  • Ipf1
  • IDX-1
  • STF-1
  • pdx-1
  • IPF-1
  • Mody4

Status ES CellsMice
tm1b
Mice
tm1a
phenotype data available

Links MGI:102851    Ensembl Gene    Ensembl Orthologs    My Genes   

Viability Homozygous - Lethal

Phenotype associations for Pdx1

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Pdx1 data for that phenotype.

Embryo Data: 3D Embryo Imaging
Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
preweaning lethality, complete penetrance Pdx1tm1b(EUCOMM)Wtsi HOM Female Male n/a 0.0
decreased bone mineral density Pdx1tm1b(EUCOMM)Wtsi HET Male postnatal 8.82E-6

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No (2/415)
Aorta 2 No
Bone 2 No
Brain 2 No
Brainstem 2 No
Brown adipose tissue 2 No
Cartilage tissue 2 No
Cecum 2 No (12/383)
Cerebellum 2 No
Cerebral cortex 2 No
Esophagus 2 No (7/415)
Eye 2 No
Gall bladder 2 No
Heart 2 No
Hippocampus 2 No
Hypothalamus 2 No
Kidney 2 No (18/584)
Large intestine 2 No (10/584)
Liver 2 No
Lower urinary tract 2 No
Lung 2 No
Lymph node 2 No
Mammary gland 2 No
Mesenteric lymph node 2 No
Olfactory lobe 2 No
Oral epithelium 2 No
Ovary 2 No (1/584)
Oviduct 2 No
Pancreas 2 No (5/584) (2/2)
Parathyroid gland 2 No
Peripheral nervous system 2 No
Peyer's patch 2 No
Pituitary gland 2 No
Prostate gland 2 No (12/584) (1/2)
Skeletal muscle 2 No
Skin 2 No
Small intestine 2 No (9/584)
Spinal cord 2 No
Spleen 2 No (2/584)
Stomach 2 No (12/584)
Striatum 2 No
Testis 2 No (2/584) (1/2)
Thymus 2 No
Thyroid gland 2 No (15/584)
Trachea 2 No
Trigeminal V nerve 2 No
Urinary bladder 2 No
Uterus 2 No
Vas deferens 2 No (15/388)
Vascular system 2 No
White adipose tissue 2 No
Expression in Anatomogram

Tissues/organs lacZ+ expression

    postnatal mouse reproductive system exocrine system trunk
No expression image was found for this adult tab

 Expression    No Expression    No Tissue Available    Ambiguous  

Anatomy #HET Specimens WT Expr Mutant Expr Images
Heart atrium 2 (1/47)
Axial skeleton 2 (1/51)
Brain 2 (6/485)
Central nervous system ganglion 2 (1/51)
Cranium 2 (1/46)
Dorsal root ganglion 2 (1/47)
Ear 2 (1/485)
Embryo 2 (1/485) (2/2)
Outer ear 2 (1/47)
Eye 2 (1/485)
Femur pre-cartilage condensation 2 (1/46)
Foot 2 (1/485)
Forearm 2 (1/282)
Forebrain 2 (1/485)
Forelimb 2 (1/485)
Fronto-nasal process 2 (1/48)
Gut 2 (1/50)
Hand 2 (1/485)
Head 2 (5/485)
Head mesenchyme 2 (1/47)
Heart 2 (1/485)
Heart ventricle 2 (1/47)
Hindbrain 2 (6/485)
Hindlimb 2 (1/485)
Humerus pre-cartilage condensation 2 (1/46)
Inner ear 2 (1/46)
Intestine 2 (1/47)
Liver 2 (1/485)
Lower leg 2 (1/282)
Lung 2 (1/485)
Mandibular process 2 (1/485)
Maxillary process 2 (1/485)
Mesonephros of female 2 (1/46)
Mesonephros of male 2 (1/46)
Metanephros 2 (1/46)
Midbrain 2 (1/485)
Nasal septum 2 (1/47)
Nose 2 (1/51)
Notochord 2 (1/47)
Oral cavity 2 (1/485)
Outflow tract 2 (1/47)
Pancreas 2 (1/46) (2/2)
Pericardium 2 (1/46)
Pharynx 2 (1/46)
Radius-ulna pre-cartilage condensation 2 (1/46)
Rib pre-cartilage condensation 2 (1/46)
Skeleton 2 (1/51)
Skin 2 (1/485)
Spinal cord 2 (1/50)
Stomach 2 (1/46)
Tail 2 (1/485)
Tail somite 2 (1/485)
Thoracic vertebral cartilage condensation 2 (1/46)
Tongue 2 (1/46)
Trachea 2 (1/50)
Trunk mesenchyme 2 (1/47)
Umbilical artery embryonic part 2 (1/47)
Umbilical vein embryonic part 2 (1/47)
Upper arm 2 (1/282)
Upper leg 2 (1/282)
Urinary system 2 (1/50)
Vibrissa 2 (1/47)


Associated Images

Phenotype associated images not available

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Pdx1tm1b(EUCOMM)Wtsi Reporter-tagged deletion allele (post-Cre)
Vector
Gene
Pdx1tm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene