Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Forelimb digit - size
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Forelimb digit - size
|
HET
|
7f:8m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Tail - thickness
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Tail - thickness
|
HET
|
7f:8m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Clinical Chemistry / Alanine aminotransferase
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Clinical Chemistry / Alanine aminotransferase
|
HET
|
7f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.673
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Eye Morphology / Ophthalmoscope Observation
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Eye Morphology / Ophthalmoscope Observation
|
HET
|
6f:8m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Coat - hair distribution - back
|
HOM
|
2f:m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Coat - hair distribution - back
|
HET
|
7f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Echo / LVPWd
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Echo / LVPWd
|
HET
|
7f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0129
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Eye Morphology / Bulging eye
|
HET
|
7f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Eye Morphology / Bulging eye
|
HOM
|
2f:m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Forelimb nail - shape
|
HET
|
7f:8m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Forelimb nail - shape
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Electrocardiogram (ECG) / RR
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Electrocardiogram (ECG) / RR
|
HET
|
7f:8m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.732
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Skin texture - whole body
|
HET
|
7f:8m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Skin texture - whole body
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Eye Morphology / Left vitreous humour thickness
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Eye Morphology / Left vitreous humour thickness
|
HET
|
7f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.266
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Trunk curl
|
HET
|
7f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Trunk curl
|
HOM
|
2f:m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Clinical Chemistry / Creatinine
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Clinical Chemistry / Creatinine
|
HET
|
7f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.841
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Eye Morphology / Iris/Pupil
|
HET
|
7f:8m
|
Fisher Exact Test framework
|
0.385
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Eye Morphology / Iris/Pupil
|
HOM
|
2f:m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
X-ray / Number of thoracic vertebrae
|
HET
|
5f:5m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
X-ray / Number of thoracic vertebrae
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Hematology / Mean cell hemoglobin concentration
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Hematology / Mean cell hemoglobin concentration
|
HET
|
7f:6m
|
Linear Mixed Model framework, LME, not including Weight
|
0.677
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Indirect Calorimetry / Body weight before experiment
|
HOM
|
1f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Indirect Calorimetry / Body weight before experiment
|
HET
|
7f:8m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP2
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP2
|
HET
|
7f:8m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Fear Conditioning / % Pre-cue freezing total
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Fear Conditioning / % Pre-cue freezing total
|
HET
|
7f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.00102
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
X-ray / Radius
|
HET
|
5f:5m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
X-ray / Radius
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Heart Weight / Heart weight normalised against body weight
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Heart Weight / Heart weight normalised against body weight
|
HET
|
6f:8m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Eye Morphology / Corneal deposits
|
HET
|
7f:8m
|
Fisher Exact Test framework
|
0.0971
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Eye Morphology / Corneal deposits
|
HOM
|
2f:m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Indirect Calorimetry / Total food intake
|
HOM
|
1f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Indirect Calorimetry / Total food intake
|
HET
|
7f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.000257
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Fear Conditioning / % Context freezing total
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Fear Conditioning / % Context freezing total
|
HET
|
7f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.130
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
X-ray / Fibula
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
X-ray / Fibula
|
HET
|
5f:5m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Open Field / Percentage center time
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Open Field / Percentage center time
|
HET
|
7f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.0642
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Hematology / Eosinophil differential count
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Hematology / Eosinophil differential count
|
HET
|
7f:6m
|
Linear Mixed Model framework, LME, not including Weight
|
0.477
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
X-ray / Shape of vertebrae
|
HET
|
5f:5m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
X-ray / Shape of vertebrae
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Auditory Brain Stem Response / 6kHz-evoked ABR Threshold
|
HET
|
2f:2m
|
Reference Range Plus Test framework; quantile = 0.95 (Tails probability = 0.025)
|
0.0261
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Auditory Brain Stem Response / 6kHz-evoked ABR Threshold
|
HOM
|
2f:m
|
Reference Range Plus Test framework; quantile = 0.95 (Tails probability = 0.025)
|
0.0261
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Body Composition (DEXA lean/fat) / Body length
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Body Composition (DEXA lean/fat) / Body length
|
HET
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.0616
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
X-ray / Brachydactyly
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
X-ray / Brachydactyly
|
HET
|
5f:5m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Fear Conditioning / % Freezing duration cue-2
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Fear Conditioning / % Freezing duration cue-2
|
HET
|
7f:8m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Vibrissae - presence
|
HOM
|
2f:m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Vibrissae - presence
|
HET
|
7f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Thyroid
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Thyroid
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Thyroid
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Thyroid
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Thyroid
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Lower teeth appearance
|
HET
|
7f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Lower teeth appearance
|
HOM
|
2f:m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
X-ray / Scapulae
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
X-ray / Scapulae
|
HET
|
5f:5m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Shock Threshold / Shock Intensity Vocalization
|
HET
|
7f:8m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Shock Threshold / Shock Intensity Vocalization
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Eye Morphology / Lens Opacity
|
HET
|
7f:8m
|
Fisher Exact Test framework
|
0.676
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Eye Morphology / Lens Opacity
|
HOM
|
2f:m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Skin texture - back paws
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Skin texture - back paws
|
HET
|
7f:8m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Open Field / Number of Rears
|
HOM
|
8f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Open Field / Number of Rears
|
HET
|
28f:32m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Forelimbs - shape
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Forelimbs - shape
|
HET
|
7f:8m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Open Field / Periphery distance travelled
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Open Field / Periphery distance travelled
|
HET
|
7f:8m
|
Linear Mixed Model framework, LME, including Weight
|
6.53×10-09
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Eye Morphology / Corneal mineralization
|
HOM
|
2f:m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Eye Morphology / Corneal mineralization
|
HET
|
7f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
X-ray / Zygomatic bone
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
X-ray / Zygomatic bone
|
HET
|
5f:5m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Heart Weight / Body weight
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Heart Weight / Body weight
|
HET
|
7f:8m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Spleen
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Spleen
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Spleen
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Spleen
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Spleen
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Fear Conditioning / Freezing duration habituation
|
HOM
|
4f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Fear Conditioning / Freezing duration habituation
|
HET
|
14f:16m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Clinical Chemistry / Calcium
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Clinical Chemistry / Calcium
|
HET
|
7f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.747
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Echo / HR
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Echo / HR
|
HET
|
7f:8m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.00915
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Open Field / Percentage center movement time
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Open Field / Percentage center movement time
|
HET
|
7f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.0300
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
X-ray / Shape of ribs
|
HOM
|
2f:m
|
Fisher Exact Test framework
|
0.115
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
X-ray / Shape of ribs
|
HET
|
5f:5m
|
Fisher Exact Test framework
|
0.250
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Tail elevation
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Tail elevation
|
HET
|
7f:8m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Epididymis
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Epididymis
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Epididymis
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Epididymis
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Epididymis
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Contact righting
|
HET
|
7f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Contact righting
|
HOM
|
2f:m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Skin color - ear
|
HET
|
7f:8m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Skin color - ear
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Hindlimb nail - number
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Hindlimb nail - number
|
HET
|
7f:8m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Electrocardiogram (ECG) / Number of signals
|
HET
|
7f:8m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Electrocardiogram (ECG) / Number of signals
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Hematology / Hematocrit
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Hematology / Hematocrit
|
HET
|
7f:6m
|
Linear Mixed Model framework, LME, including Weight
|
0.239
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Grip Strength / Forelimb and hindlimb grip strength normalised against body weight
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Grip Strength / Forelimb and hindlimb grip strength normalised against body weight
|
HET
|
7f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.148
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Esophagus
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Esophagus
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Esophagus
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Esophagus
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Esophagus
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Coat - hair texture / appearance - head
|
HOM
|
2f:m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Coat - hair texture / appearance - head
|
HET
|
7f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Grip Strength / Body weight
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Grip Strength / Body weight
|
HET
|
7f:8m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Intraperitoneal glucose tolerance test (IPGTT) / Area under glucose response curve
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Intraperitoneal glucose tolerance test (IPGTT) / Area under glucose response curve
|
HET
|
5f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.000568
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Coat - color - abdomen
|
HOM
|
2f:m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Coat - color - abdomen
|
HET
|
7f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP1_S
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP1_S
|
HET
|
7f:8m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Eye Morphology / Pupil Dilation
|
HET
|
7f:8m
|
Fisher Exact Test framework
|
0.315
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Eye Morphology / Pupil Dilation
|
HOM
|
2f:m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Fear Conditioning / % Freezing duration habituation-2
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Fear Conditioning / % Freezing duration habituation-2
|
HET
|
7f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.521
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI3
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI3
|
HET
|
7f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0521
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Body Composition (DEXA lean/fat) / Fat mass
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Body Composition (DEXA lean/fat) / Fat mass
|
HET
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.549
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Auditory Brain Stem Response / 30kHz-evoked ABR Threshold
|
HET
|
2f:2m
|
Reference Range Plus Test framework; quantile = 0.95 (Tails probability = 0.025)
|
0.0261
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Auditory Brain Stem Response / 30kHz-evoked ABR Threshold
|
HOM
|
2f:m
|
Reference Range Plus Test framework; quantile = 0.95 (Tails probability = 0.025)
|
0.0261
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Eye Morphology / Left inner nuclear layer
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Eye Morphology / Left inner nuclear layer
|
HET
|
7f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.879
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Clinical Chemistry / Phosphorus
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Clinical Chemistry / Phosphorus
|
HET
|
7f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.626
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Hindpaw - shape
|
HOM
|
2f:m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Hindpaw - shape
|
HET
|
7f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Tremor
|
HOM
|
2f:m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Tremor
|
HET
|
7f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Viability Primary Screen / Viability Outcome
|
HOM
|
f:m
|
Supplied as data
|
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Genitalia - morphology
|
HET
|
7f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Genitalia - morphology
|
HOM
|
2f:m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Hematology / Large Unstained Cell (LUC) count
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Hematology / Large Unstained Cell (LUC) count
|
HET
|
7f:6m
|
Linear Mixed Model framework, LME, including Weight
|
0.640
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Lymph node
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Lymph node
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Lymph node
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Lymph node
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Lymph node
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Brain
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Brain
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Brain
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Brain
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Brain
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Indirect Calorimetry / Total water intake
|
HOM
|
1f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Indirect Calorimetry / Total water intake
|
HET
|
7f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.00451
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Hematology / Lymphocyte cell count
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Hematology / Lymphocyte cell count
|
HET
|
7f:6m
|
Linear Mixed Model framework, LME, including Weight
|
0.0148
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Head morphology
|
HET
|
7f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Head morphology
|
HOM
|
2f:m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Electrocardiogram (ECG) / ST
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Electrocardiogram (ECG) / ST
|
HET
|
7f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.423
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Indirect Calorimetry / Respiratory Exchange Ratio
|
HOM
|
1f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Indirect Calorimetry / Respiratory Exchange Ratio
|
HET
|
5f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.0319
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Upper teeth appearance
|
HOM
|
2f:m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Upper teeth appearance
|
HET
|
7f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Indirect Calorimetry / Carbon dioxide production
|
HOM
|
22f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Indirect Calorimetry / Carbon dioxide production
|
HET
|
146f:173m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Intraperitoneal glucose tolerance test (IPGTT) / Body Weight
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Intraperitoneal glucose tolerance test (IPGTT) / Body Weight
|
HET
|
5f:8m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Open Field / Center distance travelled
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Open Field / Center distance travelled
|
HET
|
7f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.00809
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Auditory Brain Stem Response / 18kHz-evoked ABR Threshold
|
HOM
|
2f:m
|
Reference Range Plus Test framework; quantile = 0.95 (Tails probability = 0.025)
|
0.0261
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Auditory Brain Stem Response / 18kHz-evoked ABR Threshold
|
HET
|
2f:2m
|
Reference Range Plus Test framework; quantile = 0.95 (Tails probability = 0.025)
|
0.0261
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Eye Morphology / Corneal vascularization
|
HOM
|
2f:m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Eye Morphology / Corneal vascularization
|
HET
|
7f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Eye Morphology / Retinal Blood Vessels Pattern
|
HET
|
7f:8m
|
Fisher Exact Test framework
|
6.05×10-05
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Eye Morphology / Retinal Blood Vessels Pattern
|
HOM
|
2f:m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Clinical Chemistry / Triglycerides
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Clinical Chemistry / Triglycerides
|
HET
|
7f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.474
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Fear Conditioning / Freezing duration pre-cue
|
HOM
|
4f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Fear Conditioning / Freezing duration pre-cue
|
HET
|
14f:16m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
X-ray / Clavicle
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
X-ray / Clavicle
|
HET
|
5f:5m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Eye Morphology / Right total retinal thickness
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Eye Morphology / Right total retinal thickness
|
HET
|
6f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.236
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Body Weight / Body weight curve
|
HET
|
53f:59m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Body Weight / Body weight curve
|
HOM
|
15f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Fear Conditioning / % Freezing duration context-1
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Fear Conditioning / % Freezing duration context-1
|
HET
|
7f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.557
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Auditory Brain Stem Response / Body weight
|
HET
|
2f:2m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Auditory Brain Stem Response / Body weight
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Hematology / Platelet count
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Hematology / Platelet count
|
HET
|
7f:6m
|
Linear Mixed Model framework, LME, including Weight
|
0.360
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Activity (body position)
|
HET
|
7f:8m
|
Fisher Exact Test framework
|
0.232
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Activity (body position)
|
HOM
|
2f:m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP1
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP1
|
HET
|
7f:8m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Liver
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Liver
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Liver
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Liver
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Liver
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Hindlimb digit - size
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Hindlimb digit - size
|
HET
|
7f:8m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Fear Conditioning / % Freezing duration habituation-1
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Fear Conditioning / % Freezing duration habituation-1
|
HET
|
7f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0120
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Indirect Calorimetry / Cumulative food intake
|
HET
|
154f:176m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Indirect Calorimetry / Cumulative food intake
|
HOM
|
22f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
X-ray / Digit integrity
|
HET
|
5f:5m
|
Fisher Exact Test framework
|
0.594
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
X-ray / Digit integrity
|
HOM
|
2f:m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Thymus
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Thymus
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Thymus
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Thymus
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Eye Morphology / Slit Lamp observation
|
HOM
|
1f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Skin texture - snout
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Skin texture - snout
|
HET
|
7f:8m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Clinical Chemistry / Total protein
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Clinical Chemistry / Total protein
|
HET
|
7f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.00178
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Eye Morphology / Pupil Position
|
HET
|
7f:8m
|
Fisher Exact Test framework
|
0.335
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Eye Morphology / Pupil Position
|
HOM
|
2f:m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Body Composition (DEXA lean/fat) / Fat/Body weight
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Body Composition (DEXA lean/fat) / Fat/Body weight
|
HET
|
7f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.537
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Hindlimbs - position
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Hindlimbs - position
|
HET
|
7f:8m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
X-ray / Number of cervical vertebrae
|
HET
|
5f:5m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
X-ray / Number of cervical vertebrae
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Open Field / Latency to center entry
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Open Field / Latency to center entry
|
HET
|
7f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.317
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Eye Morphology / Eyelid closure
|
HOM
|
2f:m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Eye Morphology / Eyelid closure
|
HET
|
7f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Shock Threshold / Shock Intensity Jump
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Shock Threshold / Shock Intensity Jump
|
HET
|
7f:8m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Forelimbs - size
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Forelimbs - size
|
HET
|
7f:8m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
X-ray / Fusion of vertebrae
|
HET
|
5f:5m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
X-ray / Fusion of vertebrae
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Echo / LVIDd
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Echo / LVIDd
|
HET
|
7f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.784
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Mammary gland
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Mammary gland
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Mammary gland
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Mammary gland
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Mammary gland
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
X-ray / Tibia
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
X-ray / Tibia
|
HET
|
5f:5m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Tail - morphology
|
HET
|
7f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Tail - morphology
|
HOM
|
2f:m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Coat - color pattern - abdomen
|
HET
|
7f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Coat - color pattern - abdomen
|
HOM
|
2f:m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Eye Morphology / Iris transilumination
|
HET
|
7f:8m
|
Fisher Exact Test framework
|
0.0977
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Eye Morphology / Iris transilumination
|
HOM
|
2f:m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Clinical Chemistry / Aspartate aminotransferase
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Clinical Chemistry / Aspartate aminotransferase
|
HET
|
7f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.259
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Hindlimb nail - length
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Hindlimb nail - length
|
HET
|
7f:8m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Hematology / Eosinophil cell count
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Hematology / Eosinophil cell count
|
HET
|
7f:6m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.287
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Vocalization
|
HET
|
7f:8m
|
Fisher Exact Test framework
|
0.406
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Vocalization
|
HOM
|
2f:m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Grip Strength / Forelimb and hindlimb grip strength measurement mean
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Grip Strength / Forelimb and hindlimb grip strength measurement mean
|
HET
|
7f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.215
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Hematology / Hemoglobin
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Hematology / Hemoglobin
|
HET
|
7f:6m
|
Linear Mixed Model framework, LME, including Weight
|
0.825
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Indirect Calorimetry / Cumulative water intake
|
HOM
|
22f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Indirect Calorimetry / Cumulative water intake
|
HET
|
154f:176m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Indirect Calorimetry / Heat production (metabolic rate)
|
HET
|
146f:173m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Indirect Calorimetry / Heat production (metabolic rate)
|
HOM
|
22f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
X-ray / Syndactylism
|
HET
|
5f:5m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
X-ray / Syndactylism
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Open Field / Whole arena resting time
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Open Field / Whole arena resting time
|
HET
|
7f:8m
|
Linear Mixed Model framework, LME, including Weight
|
6.85×10-18
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Teeth presence
|
HET
|
7f:8m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Teeth presence
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Eye Morphology / Vitreous
|
HET
|
7f:8m
|
Fisher Exact Test framework
|
5.31×10-07
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Eye Morphology / Vitreous
|
HOM
|
2f:m
|
Fisher Exact Test framework
|
0.00207
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Eye Morphology / Lens
|
HET
|
7f:8m
|
Fisher Exact Test framework
|
0.670
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Eye Morphology / Lens
|
HOM
|
2f:m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Head size
|
HET
|
7f:8m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Head size
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Grip Strength / Forelimb grip strength normalised against body weight
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Grip Strength / Forelimb grip strength normalised against body weight
|
HET
|
7f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.823
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Eye Morphology / Left corneal thickness
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Eye Morphology / Left corneal thickness
|
HET
|
7f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.156
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Coat - color pattern - back
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Coat - color pattern - back
|
HET
|
7f:8m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Eye Morphology / Optic Disc
|
HET
|
7f:8m
|
Fisher Exact Test framework
|
0.217
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Eye Morphology / Optic Disc
|
HOM
|
2f:m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Open Field / Center average speed
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Open Field / Center average speed
|
HET
|
7f:8m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.150
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Challenge Whole Body Plethysmography / Enhanced pause (Penh)
|
HET
|
227f:422m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Challenge Whole Body Plethysmography / Enhanced pause (Penh)
|
HOM
|
143f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Eye Morphology / Narrow eye opening
|
HET
|
7f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Eye Morphology / Narrow eye opening
|
HOM
|
2f:m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Heart Weight / Heart weight
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Heart Weight / Heart weight
|
HET
|
6f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.0164
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Forepaw - shape
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Forepaw - shape
|
HET
|
7f:8m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
X-ray / Alive
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
X-ray / Alive
|
HET
|
5f:5m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Body Composition (DEXA lean/fat) / Bone Mineral Content (excluding skull)
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Body Composition (DEXA lean/fat) / Bone Mineral Content (excluding skull)
|
HET
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.988
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Hematology / Neutrophil differential count
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Hematology / Neutrophil differential count
|
HET
|
7f:6m
|
Linear Mixed Model framework, LME, including Weight
|
0.0972
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Skin color - snout
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Skin color - snout
|
HET
|
7f:8m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Prostate
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Prostate
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Prostate
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Prostate
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Prostate
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Coat - hair texture / appearance - back
|
HET
|
7f:8m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Coat - hair texture / appearance - back
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Skin
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Skin
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Skin
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Skin
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Skin
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Clinical Chemistry / HDL-cholesterol
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Clinical Chemistry / HDL-cholesterol
|
HET
|
7f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.0413
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Lung
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Lung
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Lung
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Lung
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Lung
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Eye Morphology / Persistence of hyaloid vascular system
|
HET
|
7f:8m
|
Fisher Exact Test framework
|
1.58×10-07
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Eye Morphology / Persistence of hyaloid vascular system
|
HOM
|
2f:m
|
Fisher Exact Test framework
|
0.581
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI2
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI2
|
HET
|
7f:8m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.222
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - S
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - S
|
HET
|
7f:8m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.137
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Eye Morphology / Pupil Shape
|
HET
|
7f:8m
|
Fisher Exact Test framework
|
0.325
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Eye Morphology / Pupil Shape
|
HOM
|
2f:m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Intraperitoneal glucose tolerance test (IPGTT) / Blood glucose concentration
|
HOM
|
10f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Intraperitoneal glucose tolerance test (IPGTT) / Blood glucose concentration
|
HET
|
25f:40m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Hot Plate / Type of response
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Hot Plate / Type of response
|
HET
|
7f:8m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Open Field / Periphery average speed
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Open Field / Periphery average speed
|
HET
|
7f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0927
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
X-ray / Processes on vertebrae
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
X-ray / Processes on vertebrae
|
HET
|
5f:5m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Fear Conditioning / Freezing duration cue
|
HET
|
14f:16m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Fear Conditioning / Freezing duration cue
|
HOM
|
4f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Eye Morphology / Eye
|
HOM
|
2f:m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Eye Morphology / Eye
|
HET
|
7f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Eye Morphology / Right vitreous humor thickness
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Eye Morphology / Right vitreous humor thickness
|
HET
|
6f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.292
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
X-ray / Maxilla/Pre-maxilla
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
X-ray / Maxilla/Pre-maxilla
|
HET
|
5f:5m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Fear Conditioning / Context freezing total
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Fear Conditioning / Context freezing total
|
HET
|
7f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.131
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Transfer arousal
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Transfer arousal
|
HET
|
7f:8m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Hematology / Lymphocyte differential count
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Hematology / Lymphocyte differential count
|
HET
|
7f:6m
|
Linear Mixed Model framework, LME, including Weight
|
0.00745
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Eye Morphology / Right anterior chamber depth
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Eye Morphology / Right anterior chamber depth
|
HET
|
6f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0492
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Pancreas
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Pancreas
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Pancreas
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Pancreas
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Pancreas
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Mouth morphology
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Mouth morphology
|
HET
|
7f:8m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Hematology / Monocyte differential count
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Hematology / Monocyte differential count
|
HET
|
7f:6m
|
Linear Mixed Model framework, LME, including Weight
|
0.293
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Head bobbing
|
HET
|
7f:8m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Head bobbing
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Fear Conditioning / % Freezing duration context-2
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Fear Conditioning / % Freezing duration context-2
|
HET
|
7f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0626
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Heart Weight / Tibia length
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Heart Weight / Tibia length
|
HET
|
5f:5m
|
Linear Mixed Model framework, LME, including Weight
|
0.0872
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Hematology / Sample clotted
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Hematology / Sample clotted
|
HET
|
7f:6m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Spinal cord
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Spinal cord
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Spinal cord
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Spinal cord
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Spinal cord
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Body Composition (DEXA lean/fat) / Lean/Body weight
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Body Composition (DEXA lean/fat) / Lean/Body weight
|
HET
|
7f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.188
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
X-ray / Number of ribs right
|
HET
|
5f:5m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
X-ray / Number of ribs right
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Skin texture - ear
|
HET
|
7f:8m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Skin texture - ear
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Body Composition (DEXA lean/fat) / Body weight
|
HET
|
7f:7m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Body Composition (DEXA lean/fat) / Body weight
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Open Field / Distance travelled - total
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Open Field / Distance travelled - total
|
HET
|
7f:8m
|
Linear Mixed Model framework, LME, including Weight
|
7.28×10-10
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Shock Threshold / Jump response
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Shock Threshold / Jump response
|
HET
|
7f:8m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Snout size
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Snout size
|
HET
|
7f:8m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Electrocardiogram (ECG) / PR
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Electrocardiogram (ECG) / PR
|
HET
|
7f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.697
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Eye Morphology / Synechia
|
HET
|
7f:8m
|
Fisher Exact Test framework
|
0.367
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Eye Morphology / Synechia
|
HOM
|
2f:m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Auditory Brain Stem Response / 24kHz-evoked ABR Threshold
|
HOM
|
2f:m
|
Reference Range Plus Test framework; quantile = 0.95 (Tails probability = 0.025)
|
0.0280
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Auditory Brain Stem Response / 24kHz-evoked ABR Threshold
|
HET
|
2f:2m
|
Reference Range Plus Test framework; quantile = 0.95 (Tails probability = 0.025)
|
0.0280
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Clinical Chemistry / Total cholesterol
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Clinical Chemistry / Total cholesterol
|
HET
|
7f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.193
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Genitalia - size
|
HET
|
7f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Genitalia - size
|
HOM
|
2f:m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Clinical Chemistry / Cholesterol ratio
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Clinical Chemistry / Cholesterol ratio
|
HET
|
7f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0288
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Open Field / Periphery permanence time
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Open Field / Periphery permanence time
|
HET
|
7f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.0641
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Eye Morphology / Right inner nuclear layer
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Eye Morphology / Right inner nuclear layer
|
HET
|
6f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.279
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Clinical Chemistry / Albumin
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Clinical Chemistry / Albumin
|
HET
|
7f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.145
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Forelimb nail - length
|
HET
|
7f:8m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Forelimb nail - length
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Intraperitoneal glucose tolerance test (IPGTT) / Initial response to glucose challenge
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Intraperitoneal glucose tolerance test (IPGTT) / Initial response to glucose challenge
|
HET
|
5f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0752
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Electrocardiogram (ECG) / HR
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Electrocardiogram (ECG) / HR
|
HET
|
7f:8m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.911
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Echo / LVAWd
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Echo / LVAWd
|
HET
|
7f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.108
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Aggression
|
HOM
|
2f:m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Aggression
|
HET
|
7f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Open Field / Number of center entries
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Open Field / Number of center entries
|
HET
|
7f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.00185
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
X-ray / Pelvis
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
X-ray / Pelvis
|
HET
|
5f:5m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Hindlimbs - shape
|
HET
|
7f:8m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Hindlimbs - shape
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Grip Strength / Forelimb grip strength measurement mean
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Grip Strength / Forelimb grip strength measurement mean
|
HET
|
7f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.793
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Adrenal gland
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Adrenal gland
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Adrenal gland
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Adrenal gland
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Adrenal gland
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Startle response
|
HOM
|
2f:m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Startle response
|
HET
|
7f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Rotarod / Latency to fall
|
HET
|
21f:24m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Rotarod / Latency to fall
|
HOM
|
6f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - BN
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - BN
|
HET
|
7f:8m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Urinary bladder
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Urinary bladder
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Urinary bladder
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Urinary bladder
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Urinary bladder
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Eye Morphology / Eyelid morphology
|
HET
|
7f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Eye Morphology / Eyelid morphology
|
HOM
|
2f:m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Forelimb digit - shape
|
HET
|
7f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Forelimb digit - shape
|
HOM
|
2f:m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Hematology / Mean cell volume
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Hematology / Mean cell volume
|
HET
|
7f:6m
|
Linear Mixed Model framework, LME, including Weight
|
0.000264
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Gall bladder
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Gall bladder
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Gall bladder
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Gall bladder
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Gall bladder
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Coat - color - back
|
HOM
|
2f:m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Coat - color - back
|
HET
|
7f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
X-ray / Femur
|
HET
|
5f:5m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
X-ray / Femur
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Challenge Whole Body Plethysmography / Tidal volume (TVb)
|
HET
|
227f:422m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Challenge Whole Body Plethysmography / Tidal volume (TVb)
|
HOM
|
143f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Eye Morphology / Cornea
|
HET
|
7f:8m
|
Fisher Exact Test framework
|
0.877
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Eye Morphology / Cornea
|
HOM
|
2f:m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Open Field / Center permanence time
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Open Field / Center permanence time
|
HET
|
7f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.0642
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Eye Morphology / Left anterior chamber depth
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Eye Morphology / Left anterior chamber depth
|
HET
|
7f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.346
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Auditory Brain Stem Response / 12kHz-evoked ABR Threshold
|
HOM
|
2f:m
|
Reference Range Plus Test framework; quantile = 0.95 (Tails probability = 0.025)
|
0.0410
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Auditory Brain Stem Response / 12kHz-evoked ABR Threshold
|
HET
|
2f:2m
|
Reference Range Plus Test framework; quantile = 0.95 (Tails probability = 0.025)
|
0.0410
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Grip Strength / Forelimb grip strength measurement
|
HET
|
21f:24m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Grip Strength / Forelimb grip strength measurement
|
HOM
|
6f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Hindpaw - size
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Hindpaw - size
|
HET
|
7f:8m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Open Field / Whole arena permanence
|
HET
|
7f:8m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Open Field / Whole arena permanence
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Fear Conditioning / % Freezing duration pre-cue-2
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Fear Conditioning / % Freezing duration pre-cue-2
|
HET
|
7f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.310
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Rotarod / Body weight
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Rotarod / Body weight
|
HET
|
7f:8m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Hematology / Basophil cell count
|
HET
|
7f:6m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Hematology / Basophil cell count
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Body Composition (DEXA lean/fat) / Bone Mineral Density (excluding skull)
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Body Composition (DEXA lean/fat) / Bone Mineral Density (excluding skull)
|
HET
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.690
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Upper lip morphology
|
HET
|
7f:8m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Upper lip morphology
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Locomotor activity
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Locomotor activity
|
HET
|
7f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.108
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Hematology / Red blood cell count
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Hematology / Red blood cell count
|
HET
|
7f:6m
|
Linear Mixed Model framework, LME, including Weight
|
0.257
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Clinical Chemistry / LIH (Hemolysis Severity - available on AU analysers)
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Clinical Chemistry / LIH (Hemolysis Severity - available on AU analysers)
|
HET
|
7f:8m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Skeletal muscle
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Skeletal muscle
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Skeletal muscle
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Skeletal muscle
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Skeletal muscle
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Indirect Calorimetry / Ambulatory activity (no. of beam cuts)
|
HET
|
154f:176m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Indirect Calorimetry / Ambulatory activity (no. of beam cuts)
|
HOM
|
22f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Skin texture - tail
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Skin texture - tail
|
HET
|
7f:8m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Vibrissae - appearance
|
HET
|
7f:8m
|
Fisher Exact Test framework
|
0.0140
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Vibrissae - appearance
|
HOM
|
2f:m
|
Fisher Exact Test framework
|
0.0548
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Eye Morphology / Iris Pigmentation
|
HET
|
7f:8m
|
Fisher Exact Test framework
|
0.293
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Eye Morphology / Iris Pigmentation
|
HOM
|
2f:m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Fear Conditioning / % Freezing duration cue-1
|
HET
|
7f:8m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Fear Conditioning / % Freezing duration cue-1
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Hot Plate / Hot plate latency
|
HET
|
7f:8m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Hot Plate / Hot plate latency
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI1
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI1
|
HET
|
7f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.832
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Eye Morphology / Retinal Blood Vessels
|
HET
|
7f:8m
|
Fisher Exact Test framework
|
6.00×10-05
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Eye Morphology / Retinal Blood Vessels
|
HOM
|
2f:m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP4
|
HET
|
7f:8m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP4
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Eye Morphology / Lacrimation
|
HET
|
7f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Eye Morphology / Lacrimation
|
HOM
|
2f:m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Fear Conditioning / Freezing duration context
|
HOM
|
6f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Fear Conditioning / Freezing duration context
|
HET
|
21f:24m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
X-ray / Mandibles
|
HET
|
5f:5m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
X-ray / Mandibles
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Eye Morphology / Right corneal thickness
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Eye Morphology / Right corneal thickness
|
HET
|
6f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.942
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Hematology / Neutrophil cell count
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Hematology / Neutrophil cell count
|
HET
|
7f:6m
|
Linear Mixed Model framework, LME, not including Weight
|
0.480
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Seminal vesicle
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Seminal vesicle
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Seminal vesicle
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Seminal vesicle
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Seminal vesicle
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
X-ray / Humerus
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
X-ray / Humerus
|
HET
|
5f:5m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Skin color - back paws
|
HET
|
7f:8m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Skin color - back paws
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Large intestine
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Large intestine
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Large intestine
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Large intestine
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Large intestine
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Limb grasp
|
HOM
|
2f:m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Limb grasp
|
HET
|
7f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Skin color - whole body
|
HET
|
7f:8m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Skin color - whole body
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
X-ray / Number of digits
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
X-ray / Number of digits
|
HET
|
5f:5m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Coat - hair distribution - abdomen
|
HOM
|
2f:m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Coat - hair distribution - abdomen
|
HET
|
7f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Clinical Chemistry / Urea (Blood Urea Nitrogen - BUN)
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Clinical Chemistry / Urea (Blood Urea Nitrogen - BUN)
|
HET
|
7f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.187
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Coat - color pattern - head
|
HET
|
7f:8m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Coat - color pattern - head
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Genitalia - presence
|
HET
|
7f:8m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Genitalia - presence
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Open Field / Periphery resting time
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Open Field / Periphery resting time
|
HET
|
7f:8m
|
Linear Mixed Model framework, LME, including Weight
|
2.77×10-16
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
X-ray / Number of lumbar vertebrae
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
X-ray / Number of lumbar vertebrae
|
HET
|
5f:5m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Eye Morphology / Left outer nuclear layer
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Eye Morphology / Left outer nuclear layer
|
HET
|
7f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.148
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Hindlimb nail - shape
|
HET
|
7f:8m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Hindlimb nail - shape
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
X-ray / Ulna
|
HET
|
5f:5m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
X-ray / Ulna
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Coat - hair distribution - head
|
HET
|
7f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Coat - hair distribution - head
|
HOM
|
2f:m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Uterus
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Uterus
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Uterus
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Uterus
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Uterus
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Eye Morphology / Corneal Sclerization
|
HET
|
7f:8m
|
Fisher Exact Test framework
|
0.0837
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Eye Morphology / Corneal Sclerization
|
HOM
|
2f:m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Hindlimb digit - number
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Hindlimb digit - number
|
HET
|
7f:8m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Clinical Chemistry / Alkaline phosphatase
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Clinical Chemistry / Alkaline phosphatase
|
HET
|
7f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.0392
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Stomach
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Stomach
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Stomach
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Stomach
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Stomach
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Tail - length
|
HOM
|
2f:m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Tail - length
|
HET
|
7f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Indirect Calorimetry / Body weight after experiment
|
HOM
|
1f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Indirect Calorimetry / Body weight after experiment
|
HET
|
7f:8m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Eye Morphology / Eye Hemorrhage or Blood Presence
|
HET
|
7f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Eye Morphology / Eye Hemorrhage or Blood Presence
|
HOM
|
2f:m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Hematology / Monocyte cell count
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Hematology / Monocyte cell count
|
HET
|
7f:6m
|
Linear Mixed Model framework, LME, including Weight
|
0.640
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Open Field / Number of rears - total
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Open Field / Number of rears - total
|
HET
|
7f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.00136
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Unexpected behaviors
|
HET
|
7f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Unexpected behaviors
|
HOM
|
2f:m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
X-ray / Teeth
|
HET
|
5f:5m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
X-ray / Teeth
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Fear Conditioning / % Freezing duration context-3
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Fear Conditioning / % Freezing duration context-3
|
HET
|
7f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0756
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - Global
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - Global
|
HET
|
7f:8m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.233
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
X-ray / Number of ribs left
|
HET
|
5f:5m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
X-ray / Number of ribs left
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Open Field / Distance travelled
|
HOM
|
8f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Open Field / Distance travelled
|
HET
|
28f:32m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Hindlimbs - size
|
HOM
|
2f:m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Hindlimbs - size
|
HET
|
7f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Rotarod / Latency to fall mean
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Rotarod / Latency to fall mean
|
HET
|
7f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.214
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Skin texture - front paws
|
HET
|
7f:8m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Skin texture - front paws
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Body Composition (DEXA lean/fat) / Bone Area
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Body Composition (DEXA lean/fat) / Bone Area
|
HET
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.797
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Eye Morphology / Fusion between cornea and lens
|
HET
|
7f:8m
|
Fisher Exact Test framework
|
0.367
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Eye Morphology / Fusion between cornea and lens
|
HOM
|
2f:m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Coat - color - head
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Coat - color - head
|
HET
|
7f:8m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Electrocardiogram (ECG) / QT
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Electrocardiogram (ECG) / QT
|
HET
|
7f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.521
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Hematology / Mean corpuscular hemoglobin
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Hematology / Mean corpuscular hemoglobin
|
HET
|
7f:6m
|
Linear Mixed Model framework, LME, including Weight
|
0.0168
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Echo / LVIDs
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Echo / LVIDs
|
HET
|
7f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.169
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Fear Conditioning / % Cue freezing total
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Fear Conditioning / % Cue freezing total
|
HET
|
7f:8m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.761
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Heart Weight / Heart weight normalised against tibia length
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Heart Weight / Heart weight normalised against tibia length
|
HET
|
4f:5m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Eye Morphology / Right outer nuclear layer
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Eye Morphology / Right outer nuclear layer
|
HET
|
6f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.267
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Hindlimb digit - shape
|
HOM
|
2f:m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Hindlimb digit - shape
|
HET
|
7f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Hematology / Large Unstained Cell (LUC) differential count
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Hematology / Large Unstained Cell (LUC) differential count
|
HET
|
7f:6m
|
Linear Mixed Model framework, LME, including Weight
|
0.898
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Forepaw - size
|
HET
|
7f:8m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Forepaw - size
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Intraperitoneal glucose tolerance test (IPGTT) / Fasted blood glucose concentration
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Intraperitoneal glucose tolerance test (IPGTT) / Fasted blood glucose concentration
|
HET
|
5f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.432
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Heart
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Heart
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Heart
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Heart
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Heart
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Clinical Chemistry / Total bilirubin
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Clinical Chemistry / Total bilirubin
|
HET
|
7f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.0709
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Forelimbs - position
|
HET
|
7f:8m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Forelimbs - position
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Indirect Calorimetry / Total activity (no. of fine movement + no. of beam cuts)
|
HET
|
154f:176m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Indirect Calorimetry / Total activity (no. of fine movement + no. of beam cuts)
|
HOM
|
22f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
X-ray / Fusion of ribs
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
X-ray / Fusion of ribs
|
HET
|
5f:5m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Shock Threshold / Shock Intensity Flinch
|
HET
|
7f:8m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Shock Threshold / Shock Intensity Flinch
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP3_S
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP3_S
|
HET
|
7f:8m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Body Composition (DEXA lean/fat) / BMC/Body weight
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Body Composition (DEXA lean/fat) / BMC/Body weight
|
HET
|
7f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.980
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Lower lip morphology
|
HET
|
7f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Lower lip morphology
|
HOM
|
2f:m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Skin color - front paws
|
HET
|
7f:8m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Skin color - front paws
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Hematology / Basophil differential count
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Hematology / Basophil differential count
|
HET
|
7f:6m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Trachea
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Trachea
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Trachea
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Trachea
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Trachea
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Testes
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Testes
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Testes
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Testes
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Testes
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Coat - hair texture / appearance - abdomen
|
HET
|
7f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Coat - hair texture / appearance - abdomen
|
HOM
|
2f:m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Hot Plate / Body weight
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Hot Plate / Body weight
|
HET
|
7f:8m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Open Field / Center resting time
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Open Field / Center resting time
|
HET
|
7f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.889
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Clinical Chemistry / Glucose
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Clinical Chemistry / Glucose
|
HET
|
7f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.146
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP2_S
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP2_S
|
HET
|
7f:8m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Eye Morphology / Retinal Blood Vessels Structure
|
HOM
|
2f:m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Eye Morphology / Retinal Blood Vessels Structure
|
HET
|
7f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Eye Morphology / Left total retinal thickness
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Eye Morphology / Left total retinal thickness
|
HET
|
7f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0707
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
X-ray / Joints
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
X-ray / Joints
|
HET
|
5f:5m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Grip Strength / Forelimb and hindlimb grip strength measurement
|
HOM
|
6f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Grip Strength / Forelimb and hindlimb grip strength measurement
|
HET
|
21f:24m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Fear Conditioning / Freezing duration post-us
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Fear Conditioning / Freezing duration post-us
|
HET
|
7f:8m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Rotarod / Passive rotation
|
HOM
|
6f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Rotarod / Passive rotation
|
HET
|
21f:24m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Eye Morphology / Corneal ulcer
|
HOM
|
2f:m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Eye Morphology / Corneal ulcer
|
HET
|
7f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
X-ray / Skull shape
|
HOM
|
2f:m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
X-ray / Skull shape
|
HET
|
5f:5m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Echo / Fractional Shortening
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Echo / Fractional Shortening
|
HET
|
7f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0303
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Forelimb nail - number
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Forelimb nail - number
|
HET
|
7f:8m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Gait
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Gait
|
HET
|
7f:8m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Kidney
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Kidney
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Kidney
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Kidney
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Kidney
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Electrocardiogram (ECG) / QRS
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Electrocardiogram (ECG) / QRS
|
HET
|
7f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.745
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Indirect Calorimetry / Oxygen consumption
|
HOM
|
22f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Indirect Calorimetry / Oxygen consumption
|
HET
|
146f:173m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Ears
|
HET
|
7f:8m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Ears
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Small intestine
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Small intestine
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Small intestine
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Small intestine
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Small intestine
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Forelimb digit - number
|
HET
|
7f:8m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Forelimb digit - number
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Tail - presence
|
HET
|
7f:8m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Tail - presence
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI4
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI4
|
HET
|
7f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0105
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
X-ray / Tibia length
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
X-ray / Tibia length
|
HET
|
5f:5m
|
Linear Mixed Model framework, LME, including Weight
|
0.0477
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Body Composition (DEXA lean/fat) / Lean mass
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Body Composition (DEXA lean/fat) / Lean mass
|
HET
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.120
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP3
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP3
|
HET
|
7f:8m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Eye Morphology / Pupil Light Response
|
HET
|
7f:8m
|
Fisher Exact Test framework
|
0.304
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Eye Morphology / Pupil Light Response
|
HOM
|
2f:m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Fear Conditioning / % Freezing duration pre-cue-1
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Fear Conditioning / % Freezing duration pre-cue-1
|
HET
|
7f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
5.39×10-05
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP4_S
|
HET
|
7f:8m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP4_S
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Open Field / Whole arena average speed
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Open Field / Whole arena average speed
|
HET
|
7f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0989
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Eye Morphology / Corneal opacity
|
HET
|
7f:8m
|
Fisher Exact Test framework
|
0.850
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Eye Morphology / Corneal opacity
|
HOM
|
2f:m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
X-ray / Number of pelvic vertebrae
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
X-ray / Number of pelvic vertebrae
|
HET
|
5f:5m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Ovary
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Ovary
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Ovary
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Ovary
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Ovary
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Challenge Whole Body Plethysmography / Frequency of breathing (f)
|
HOM
|
143f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Challenge Whole Body Plethysmography / Frequency of breathing (f)
|
HET
|
227f:422m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Hematology / White blood cell count
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Hematology / White blood cell count
|
HET
|
7f:6m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0509
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Skin color - tail
|
HET
|
7f:8m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Skin color - tail
|
HOM
|
2f:m
|
|
|
NotProcessed |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Eye with optic nerve
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Eye with optic nerve
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Eye with optic nerve
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Eye with optic nerve
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Pcsk1tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Eye with optic nerve
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |