Hspa5tm1.1(KOMP)Vlcg
|
JAX
|
Electroconvulsive Threshold Testing / mA threshold inducing clonic seizure
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.000927
|
Successful |
Hspa5tm1.1(KOMP)Vlcg
|
JAX
|
Open Field - centre start / Whole arena average speed
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.223
|
Successful |
Hspa5tm1.1(KOMP)Vlcg
|
JAX
|
Hole-board Exploration / Holepoke sequence
|
HET
|
302f:303m
|
|
|
NotProcessed |
Hspa5tm1.1(KOMP)Vlcg
|
JAX
|
Sleep Wake / Light sleep bout lengths standard deviation
|
HET
|
f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.243
|
Successful |
Hspa5tm1.1(KOMP)Vlcg
|
JAX
|
Combined SHIRPA and Dysmorphology / Activity (body position)
|
HET
|
7f:11m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Hspa5tm1.1(KOMP)Vlcg
|
JAX
|
Combined SHIRPA and Dysmorphology / Head bobbing
|
HET
|
7f:11m
|
|
|
NotProcessed |
Hspa5tm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP1
|
HET
|
8f:8m
|
|
|
NotProcessed |
Hspa5tm1.1(KOMP)Vlcg
|
JAX
|
Light-Dark Test / Percent time in light
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.699
|
Successful |
Hspa5tm1.1(KOMP)Vlcg
|
JAX
|
Open Field - centre start / Center average speed
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.560
|
Successful |
Hspa5tm1.1(KOMP)Vlcg
|
JAX
|
Combined SHIRPA and Dysmorphology / Trunk curl
|
HET
|
7f:11m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Hspa5tm1.1(KOMP)Vlcg
|
JAX
|
Open Field - centre start / Center permanence time
|
HET
|
8f:8m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.0172
|
Successful |
Hspa5tm1.1(KOMP)Vlcg
|
JAX
|
Light-Dark Test / Side changes
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.383
|
Successful |
Hspa5tm1.1(KOMP)Vlcg
|
JAX
|
Gross Morphology Embryo E12.5 / Midbrain morphology
|
HET
|
18f:3m
|
Supplied as data
|
1.00
|
Successful |
Hspa5tm1.1(KOMP)Vlcg
|
JAX
|
Hole-board Exploration / Total holepokes
|
HET
|
6f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.0218
|
Successful |
Hspa5tm1.1(KOMP)Vlcg
|
JAX
|
Sleep Wake / Dark sleep bout lengths mean
|
HET
|
f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.101
|
Successful |
Hspa5tm1.1(KOMP)Vlcg
|
JAX
|
Combined SHIRPA and Dysmorphology / Unexpected behaviors
|
HET
|
7f:11m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Hspa5tm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP2
|
HET
|
8f:8m
|
|
|
NotProcessed |
Hspa5tm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - Global
|
HET
|
8f:8m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.240
|
Successful |
Hspa5tm1.1(KOMP)Vlcg
|
JAX
|
Light-Dark Test / Light side time spent
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.499
|
Successful |
Hspa5tm1.1(KOMP)Vlcg
|
JAX
|
Gross Morphology Embryo E12.5 / Neural Tube Closure
|
HET
|
18f:3m
|
Supplied as data
|
1.00
|
Successful |
Hspa5tm1.1(KOMP)Vlcg
|
JAX
|
Open Field - centre start / Periphery distance travelled
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.934
|
Successful |
Hspa5tm1.1(KOMP)Vlcg
|
JAX
|
Gross Morphology Embryo E12.5 / Forebrain morphology
|
HET
|
18f:3m
|
Supplied as data
|
1.00
|
Successful |
Hspa5tm1.1(KOMP)Vlcg
|
JAX
|
Open Field - centre start / Whole arena resting time
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.457
|
Successful |
Hspa5tm1.1(KOMP)Vlcg
|
JAX
|
Combined SHIRPA and Dysmorphology / Aggression
|
HET
|
7f:11m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Hspa5tm1.1(KOMP)Vlcg
|
JAX
|
Open Field - centre start / Number of Rears
|
HET
|
32f:32m
|
|
|
NotProcessed |
Hspa5tm1.1(KOMP)Vlcg
|
JAX
|
Light-Dark Test / Time mobile light side
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.395
|
Successful |
Hspa5tm1.1(KOMP)Vlcg
|
JAX
|
Grip Strength / Forelimb grip strength measurement mean
|
HET
|
f:5m
|
Linear Mixed Model framework, LME, including Weight
|
0.667
|
Successful |
Hspa5tm1.1(KOMP)Vlcg
|
JAX
|
Grip Strength / Forelimb grip strength measurement mean
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.873
|
Successful |
Hspa5tm1.1(KOMP)Vlcg
|
JAX
|
Combined SHIRPA and Dysmorphology / Startle response
|
HET
|
7f:11m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Hspa5tm1.1(KOMP)Vlcg
|
JAX
|
Sleep Wake / Breath rate during sleep standard deviation
|
HET
|
f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.795
|
Successful |
Hspa5tm1.1(KOMP)Vlcg
|
JAX
|
Open Field - centre start / Percentage center time
|
HET
|
8f:8m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.0172
|
Successful |
Hspa5tm1.1(KOMP)Vlcg
|
JAX
|
Gross Morphology Embryo E9.5 / Midbrain
|
HET
|
14f:5m
|
Supplied as data
|
1.00
|
Successful |
Hspa5tm1.1(KOMP)Vlcg
|
JAX
|
Open Field - centre start / Distance travelled
|
HET
|
32f:32m
|
|
|
NotProcessed |
Hspa5tm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - BN
|
HET
|
8f:8m
|
|
|
NotProcessed |
Hspa5tm1.1(KOMP)Vlcg
|
JAX
|
Gross Morphology Embryo E12.5 / Hindbrain morphology
|
HET
|
18f:3m
|
Supplied as data
|
1.00
|
Successful |
Hspa5tm1.1(KOMP)Vlcg
|
JAX
|
Combined SHIRPA and Dysmorphology / Vocalization
|
HET
|
7f:11m
|
Fisher Exact Test framework
|
0.623
|
Successful |
Hspa5tm1.1(KOMP)Vlcg
|
JAX
|
Combined SHIRPA and Dysmorphology / Touch escape
|
HET
|
7f:11m
|
|
|
NotProcessed |
Hspa5tm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP3_S
|
HET
|
8f:8m
|
|
|
NotProcessed |
Hspa5tm1.1(KOMP)Vlcg
|
JAX
|
Tail Suspension / Time immobile
|
HET
|
f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.623
|
Successful |
Hspa5tm1.1(KOMP)Vlcg
|
JAX
|
Sleep Wake / Sleep daily percent
|
HET
|
f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.416
|
Successful |
Hspa5tm1.1(KOMP)Vlcg
|
JAX
|
Light-Dark Test / Dark side time spent
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.499
|
Successful |
Hspa5tm1.1(KOMP)Vlcg
|
JAX
|
Grip Strength / Forelimb and hindlimb grip strength measurement mean
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.168
|
Successful |
Hspa5tm1.1(KOMP)Vlcg
|
JAX
|
Grip Strength / Forelimb and hindlimb grip strength measurement mean
|
HET
|
f:5m
|
Linear Mixed Model framework, LME, including Weight
|
0.492
|
Successful |
Hspa5tm1.1(KOMP)Vlcg
|
JAX
|
Sleep Wake / Sleep light phase percent
|
HET
|
f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.0923
|
Successful |
Hspa5tm1.1(KOMP)Vlcg
|
JAX
|
Open Field - centre start / Number of rears - total
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.552
|
Successful |
Hspa5tm1.1(KOMP)Vlcg
|
JAX
|
Grip Strength / Forelimb grip strength measurement
|
HET
|
f:15m
|
|
|
NotProcessed |
Hspa5tm1.1(KOMP)Vlcg
|
JAX
|
Grip Strength / Forelimb grip strength measurement
|
HET
|
24f:24m
|
|
|
NotProcessed |
Hspa5tm1.1(KOMP)Vlcg
|
JAX
|
Rotarod / Latency to fall
|
HET
|
40f:40m
|
|
|
NotProcessed |
Hspa5tm1.1(KOMP)Vlcg
|
JAX
|
Sleep Wake / Peak wake with respect to dark onset median
|
HET
|
f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.118
|
Successful |
Hspa5tm1.1(KOMP)Vlcg
|
JAX
|
Tail Suspension / Latency to immobility
|
HET
|
f:8m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.768
|
Successful |
Hspa5tm1.1(KOMP)Vlcg
|
JAX
|
Gross Morphology Embryo E9.5 / Neural tube closure
|
HET
|
14f:5m
|
Supplied as data
|
1.00
|
Successful |
Hspa5tm1.1(KOMP)Vlcg
|
JAX
|
Grip Strength / Forelimb grip strength normalised against body weight
|
HET
|
f:5m
|
Linear Mixed Model framework, LME, not including Weight
|
0.831
|
Successful |
Hspa5tm1.1(KOMP)Vlcg
|
JAX
|
Grip Strength / Forelimb grip strength normalised against body weight
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.956
|
Successful |
Hspa5tm1.1(KOMP)Vlcg
|
JAX
|
Combined SHIRPA and Dysmorphology / Locomotor activity
|
HET
|
7f:11m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.0391
|
Successful |
Hspa5tm1.1(KOMP)Vlcg
|
JAX
|
Eye Morphology / Optic Disc
|
HET
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Hspa5tm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP2_S
|
HET
|
8f:8m
|
|
|
NotProcessed |
Hspa5tm1.1(KOMP)Vlcg
|
JAX
|
Combined SHIRPA and Dysmorphology / Tail elevation
|
HET
|
7f:11m
|
|
|
NotProcessed |
Hspa5tm1.1(KOMP)Vlcg
|
JAX
|
Light-Dark Test / Time mobile dark side
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.0224
|
Successful |
Hspa5tm1.1(KOMP)Vlcg
|
JAX
|
Open Field - centre start / Periphery average speed
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.639
|
Successful |
Hspa5tm1.1(KOMP)Vlcg
|
JAX
|
Light-Dark Test / Fecal boli
|
HET
|
8f:5m
|
Linear Mixed Model framework, LME, including Weight
|
0.128
|
Successful |
Hspa5tm1.1(KOMP)Vlcg
|
JAX
|
Combined SHIRPA and Dysmorphology / Contact righting
|
HET
|
7f:11m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Hspa5tm1.1(KOMP)Vlcg
|
JAX
|
Sleep Wake / Sleep dark phase percent
|
HET
|
f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.0396
|
Successful |
Hspa5tm1.1(KOMP)Vlcg
|
JAX
|
Grip Strength / Forelimb and hindlimb grip strength normalised against body weight
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.123
|
Successful |
Hspa5tm1.1(KOMP)Vlcg
|
JAX
|
Grip Strength / Forelimb and hindlimb grip strength normalised against body weight
|
HET
|
f:5m
|
Linear Mixed Model framework, LME, not including Weight
|
0.900
|
Successful |
Hspa5tm1.1(KOMP)Vlcg
|
JAX
|
Grip Strength / Forelimb and hindlimb grip strength measurement
|
HET
|
24f:24m
|
|
|
NotProcessed |
Hspa5tm1.1(KOMP)Vlcg
|
JAX
|
Grip Strength / Forelimb and hindlimb grip strength measurement
|
HET
|
f:15m
|
|
|
NotProcessed |
Hspa5tm1.1(KOMP)Vlcg
|
JAX
|
Open Field - centre start / Distance travelled - total
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.227
|
Successful |
Hspa5tm1.1(KOMP)Vlcg
|
JAX
|
Gross Morphology Embryo E9.5 / Forebrain
|
HET
|
14f:5m
|
Supplied as data
|
1.00
|
Successful |
Hspa5tm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP1_S
|
HET
|
8f:8m
|
|
|
NotProcessed |
Hspa5tm1.1(KOMP)Vlcg
|
JAX
|
Open Field - centre start / Periphery permanence time
|
HET
|
8f:8m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.0172
|
Successful |
Hspa5tm1.1(KOMP)Vlcg
|
JAX
|
Sleep Wake / Breath rate during sleep mean
|
HET
|
f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.700
|
Successful |
Hspa5tm1.1(KOMP)Vlcg
|
JAX
|
Combined SHIRPA and Dysmorphology / Gait
|
HET
|
7f:11m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Hspa5tm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI1
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.440
|
Successful |
Hspa5tm1.1(KOMP)Vlcg
|
JAX
|
Rotarod / Learning slope
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.577
|
Successful |
Hspa5tm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP4
|
HET
|
f:5m
|
|
|
NotProcessed |
Hspa5tm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI3
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.192
|
Successful |
Hspa5tm1.1(KOMP)Vlcg
|
JAX
|
Sleep Wake / Sleep bout lengths mean
|
HET
|
f:8m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.938
|
Successful |
Hspa5tm1.1(KOMP)Vlcg
|
JAX
|
Combined SHIRPA and Dysmorphology / Tremor
|
HET
|
7f:11m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Hspa5tm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI2
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.787
|
Successful |
Hspa5tm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - S
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.314
|
Successful |
Hspa5tm1.1(KOMP)Vlcg
|
JAX
|
Light-Dark Test / Latency to first transition into dark
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.871
|
Successful |
Hspa5tm1.1(KOMP)Vlcg
|
JAX
|
Rotarod / Learning difference
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.587
|
Successful |
Hspa5tm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI4
|
HET
|
f:5m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.00237
|
Successful |
Hspa5tm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP3
|
HET
|
8f:8m
|
|
|
NotProcessed |
Hspa5tm1.1(KOMP)Vlcg
|
JAX
|
Sleep Wake / Dark sleep bout lengths standard deviation
|
HET
|
f:8m
|
Linear Model Using Generalized Least Squares framework, GLS, including Weight
|
0.129
|
Successful |
Hspa5tm1.1(KOMP)Vlcg
|
JAX
|
Combined SHIRPA and Dysmorphology / Limb grasp
|
HET
|
7f:11m
|
Fisher Exact Test framework
|
0.235
|
Successful |
Hspa5tm1.1(KOMP)Vlcg
|
JAX
|
Eye Morphology / Pupil Light Response
|
HET
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Hspa5tm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP4_S
|
HET
|
f:5m
|
|
|
NotProcessed |
Hspa5tm1.1(KOMP)Vlcg
|
JAX
|
Sleep Wake / Light sleep bout lengths mean
|
HET
|
f:8m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.204
|
Successful |
Hspa5tm1.1(KOMP)Vlcg
|
JAX
|
Combined SHIRPA and Dysmorphology / Transfer arousal
|
HET
|
7f:11m
|
|
|
NotProcessed |
Hspa5tm1.1(KOMP)Vlcg
|
JAX
|
Sleep Wake / Sleep bout lengths standard deviation
|
HET
|
f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.567
|
Successful |
Hspa5tm1.1(KOMP)Vlcg
|
JAX
|
Light-Dark Test / Percent time in dark
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.699
|
Successful |
Hspa5tm1.1(KOMP)Vlcg
|
JAX
|
Sleep Wake / Activity onset with respect to dark onset median
|
HET
|
f:3m
|
|
|
NotProcessed |
Hspa5tm1.1(KOMP)Vlcg
|
JAX
|
Rotarod / Average duration
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.535
|
Successful |
Hspa5tm1.1(KOMP)Vlcg
|
JAX
|
Open Field - centre start / Center distance travelled
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0128
|
Successful |