All data for Gnao1

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Allele Center Procedure / Parameter Zygosity Mutants Statistical
Method
P Value Status Graph
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Combined SHIRPA and Dysmorphology / Tail - thickness HET 8f:8m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Combined SHIRPA and Dysmorphology / Forelimb digit - size HET 8f:8m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Clinical Chemistry / Alanine aminotransferase HET 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0033209 Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Combined SHIRPA and Dysmorphology / Coat - hair distribution - back HET 8f:8m Fisher Exact Test framework 1.0000 Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Echo / LVPWd HET 6f:0m Mixed Model framework, linear mixed-effects model, equation withWeight 0.52124 Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Eye Morphology / Bulging eye HET 7f:8m Fisher Exact Test framework 1.0000 Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Combined SHIRPA and Dysmorphology / Forelimb nail - shape HET 8f:8m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Combined SHIRPA and Dysmorphology / Skin texture - whole body HET 8f:8m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Combined SHIRPA and Dysmorphology / Trunk curl HET 8f:8m Fisher Exact Test framework 0.061657 Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Clinical Chemistry / Creatinine HET 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.00010281 Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Eye Morphology / Iris/Pupil HET 7f:8m Fisher Exact Test framework 1.0000 Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Hematology / Mean cell hemoglobin concentration HET 5f:4m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.12979 Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Hematology / Mean cell hemoglobin concentration HET 3f:4m Not processed 1.0000 FAILED - Not enough data points in dependent variable 'IMPC_HEM_007_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell X-ray / Radius HET 6f:5m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell X-ray / Fibula HET 6f:5m Fisher Exact Test framework 1.0000 Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Hematology / Eosinophil differential count HET 5f:4m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.00018911 Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Hematology / Eosinophil differential count HET 3f:4m Not processed 1.0000 FAILED - Not enough data points in dependent variable 'IMPC_HEM_035_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Open Field / Percentage center time HET 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0085894 Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Hematology / Mean platelet volume HET 5f:4m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.44614 Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Hematology / Mean platelet volume HET 3f:4m Not processed 1.0000 FAILED - Not enough data points in dependent variable 'IMPC_HEM_019_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Echo / LVAWs HET 6f:0m Mixed Model framework, linear mixed-effects model, equation withWeight 0.13366 Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Auditory Brain Stem Response / 6kHz-evoked ABR Threshold HET 2f:2m 1.0000 Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell X-ray / Shape of vertebrae HET 6f:5m Fisher Exact Test framework 1.0000 Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Viability E18.5 Secondary Screen / Outcome HOM f:m Supplied as data 0.0000 Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell X-ray / Brachydactyly HET 6f:5m Fisher Exact Test framework 1.0000 Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Combined SHIRPA and Dysmorphology / Vibrissae - presence HET 8f:8m Fisher Exact Test framework 1.0000 Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Thyroid HET f:m Supplied as data Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Thyroid HET f:m Supplied as data Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Thyroid HET f:m Supplied as data Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Thyroid HET f:m Supplied as data Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Combined SHIRPA and Dysmorphology / Lower teeth appearance HET 8f:8m Fisher Exact Test framework 1.0000 Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell X-ray / Scapulae HET 6f:5m Fisher Exact Test framework 1.0000 Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Eye Morphology / Lens Opacity HET 7f:8m Fisher Exact Test framework 1.0000 Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Combined SHIRPA and Dysmorphology / Skin texture - back paws HET 8f:8m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Combined SHIRPA and Dysmorphology / Forelimbs - shape HET 8f:8m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Open Field / Periphery distance travelled HET 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.020829 Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Eye Morphology / Retina (combined) HET 7f:8m Not processed Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell X-ray / Zygomatic bone HET 6f:5m Fisher Exact Test framework 1.0000 Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Spleen HET f:m Supplied as data Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Spleen HET f:m Supplied as data Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Spleen HET f:m Supplied as data Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Spleen HET f:m Supplied as data Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Clinical Chemistry / Calcium HET 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.74394 Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Echo / HR HET 6f:0m Mixed Model framework, linear mixed-effects model, equation withWeight 0.52072 Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell X-ray / Shape of ribs HET 6f:5m Fisher Exact Test framework 1.0000 Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Epididymis HET f:m Supplied as data Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Epididymis HET f:m Supplied as data Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Epididymis HET f:m Supplied as data Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Epididymis HET f:m Supplied as data Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Combined SHIRPA and Dysmorphology / Contact righting HET 8f:8m Fisher Exact Test framework 0.00092557 Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Hematology / Hematocrit HET 5f:4m Mixed Model framework, linear mixed-effects model, equation withWeight 0.061280 Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Hematology / Hematocrit HET 3f:4m Not processed 1.0000 FAILED - Not enough data points in dependent variable 'IMPC_HEM_004_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Combined SHIRPA and Dysmorphology / Hindlimb nail - number HET 8f:8m Fisher Exact Test framework 1.0000 Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Combined SHIRPA and Dysmorphology / Skin color - ear HET 8f:8m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Esophagus HET f:m Supplied as data Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Esophagus HET f:m Supplied as data Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Esophagus HET f:m Supplied as data Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Esophagus HET f:m Supplied as data Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Grip Strength / Forelimb and hindlimb grip strength normalised against body weight HET 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.62679 Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Combined SHIRPA and Dysmorphology / Coat - hair texture / appearance - head HET 8f:8m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Intraperitoneal glucose tolerance test (IPGTT) / Area under glucose response curve HET 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.077348 Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Clinical Chemistry / Creatine kinase HET 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.80474 Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Combined SHIRPA and Dysmorphology / Coat - color - abdomen HET 8f:8m Fisher Exact Test framework 1.0000 Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Eye Morphology / Pupil Dilation HET 7f:8m Fisher Exact Test framework 1.0000 Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Body Composition (DEXA lean/fat) / Fat mass HET 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.00026062 Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI3 HET 6f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0055346 Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI3 HET 2f:1m Not processed 1.0000 FAILED - Not enough mutant or control data
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Clinical Chemistry / Potassium HET 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.51878 Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Auditory Brain Stem Response / 30kHz-evoked ABR Threshold HET 2f:2m 1.0000 Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Clinical Chemistry / Phosphorus HET 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.00061741 Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Combined SHIRPA and Dysmorphology / Hindpaw - shape HET 8f:8m Fisher Exact Test framework 1.0000 Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Combined SHIRPA and Dysmorphology / Tremor HET 8f:8m Fisher Exact Test framework 1.0000 Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Viability Primary Screen / Outcome HOM 17f:14m Supplied as data 0.0000 Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Viability Primary Screen / Outcome HOM 17f:14m Supplied as data 0.0000 Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Echo / End-Diastolic Diameter HET 6f:0m Mixed Model framework, linear mixed-effects model, equation withWeight 0.0013938 Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Combined SHIRPA and Dysmorphology / Genitalia - morphology HET 8f:8m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Hematology / Large Unstained Cell (LUC) count HET 5f:4m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.024729 Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Hematology / Large Unstained Cell (LUC) count HET 3f:4m Not processed 1.0000 FAILED - Not enough data points in dependent variable 'IMPC_HEM_039_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Brain HET f:m Supplied as data Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Brain HET f:m Supplied as data Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Brain HET f:m Supplied as data Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Brain HET f:m Supplied as data Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Lymph node HET f:m Supplied as data Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Lymph node HET f:m Supplied as data Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Lymph node HET f:m Supplied as data Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Lymph node HET f:m Supplied as data Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Hematology / Lymphocyte cell count HET 5f:4m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.11940 Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Hematology / Lymphocyte cell count HET 3f:4m Not processed 1.0000 FAILED - Not enough data points in dependent variable 'IMPC_HEM_032_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Combined SHIRPA and Dysmorphology / Head morphology HET 8f:8m Fisher Exact Test framework 1.0000 Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Indirect Calorimetry / Respiratory Exchange Ratio HET 0f:8m Not processed 1.0000 FAILED - testDataset returned an error, check log file
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Combined SHIRPA and Dysmorphology / Upper teeth appearance HET 8f:8m Fisher Exact Test framework 1.0000 Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Open Field / Center distance travelled HET 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 1.3093E-05 Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Auditory Brain Stem Response / 18kHz-evoked ABR Threshold HET 2f:2m 1.0000 Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Eye Morphology / Corneal vascularization HET 7f:8m Fisher Exact Test framework 1.0000 Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Eye Morphology / Retinal Blood Vessels Pattern HET 7f:8m Fisher Exact Test framework 1.0000 Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Clinical Chemistry / Triglycerides HET 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 1.3168E-05 Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell X-ray / Clavicle HET 6f:5m Fisher Exact Test framework 1.0000 Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Combined SHIRPA and Dysmorphology / Activity (body position) HET 8f:8m Fisher Exact Test framework 0.054927 Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Hematology / Platelet count HET 5f:4m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.10907 Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Hematology / Platelet count HET 3f:4m Not processed 1.0000 FAILED - Not enough data points in dependent variable 'IMPC_HEM_008_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Liver HET f:m Supplied as data Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Liver HET f:m Supplied as data Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Liver HET f:m Supplied as data Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Liver HET f:m Supplied as data Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Combined SHIRPA and Dysmorphology / Hindlimb digit - size HET 8f:8m Fisher Exact Test framework 1.0000 Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell X-ray / Digit integrity HET 6f:5m Fisher Exact Test framework 0.24093 Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Thymus HET f:m Supplied as data Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Thymus HET f:m Supplied as data Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Thymus HET f:m Supplied as data Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Thymus HET f:m Supplied as data Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Combined SHIRPA and Dysmorphology / Skin texture - snout HET 8f:8m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Clinical Chemistry / Total protein HET 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.54574 Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Echo / Respiration Rate HET 6f:0m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.35742 Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Eye Morphology / Pupil Position HET 7f:8m Fisher Exact Test framework 1.0000 Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Body Composition (DEXA lean/fat) / Fat/Body weight HET 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0013037 Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Combined SHIRPA and Dysmorphology / Hindlimbs - position HET 8f:8m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Open Field / Latency to center entry HET 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.00017353 Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Eye Morphology / Eyelid closure HET 7f:8m Fisher Exact Test framework 1.0000 Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Combined SHIRPA and Dysmorphology / Forelimbs - size HET 8f:8m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Echo / LVIDd HET 6f:0m Mixed Model framework, linear mixed-effects model, equation withWeight 0.0015994 Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell X-ray / Fusion of vertebrae HET 6f:5m Fisher Exact Test framework 1.0000 Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Mammary gland HET f:m Supplied as data Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Mammary gland HET f:m Supplied as data Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Mammary gland HET f:m Supplied as data Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Mammary gland HET f:m Supplied as data Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Combined SHIRPA and Dysmorphology / Tail - morphology HET 8f:8m Fisher Exact Test framework 1.0000 Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell X-ray / Tibia HET 6f:5m Fisher Exact Test framework 1.0000 Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Combined SHIRPA and Dysmorphology / Coat - color pattern - abdomen HET 8f:8m Fisher Exact Test framework 1.0000 Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Clinical Chemistry / Aspartate aminotransferase HET 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.067179 Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Combined SHIRPA and Dysmorphology / Hindlimb nail - length HET 8f:8m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Hematology / Eosinophil cell count HET 5f:4m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.14602 Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Hematology / Eosinophil cell count HET 3f:4m Not processed 1.0000 FAILED - Not enough data points in dependent variable 'IMPC_HEM_036_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Combined SHIRPA and Dysmorphology / Vocalization HET 8f:8m Fisher Exact Test framework 1.0000 Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Grip Strength / Forelimb and hindlimb grip strength measurement mean HET 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.33722 Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Hematology / Hemoglobin HET 5f:4m Mixed Model framework, linear mixed-effects model, equation withWeight 0.41624 Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Hematology / Hemoglobin HET 3f:4m Not processed 1.0000 FAILED - Not enough data points in dependent variable 'IMPC_HEM_003_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Open Field / Whole arena resting time HET 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 7.1545E-07 Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell X-ray / Syndactylism HET 6f:5m Fisher Exact Test framework 1.0000 Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Combined SHIRPA and Dysmorphology / Teeth presence HET 8f:8m Fisher Exact Test framework 1.0000 Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Eye Morphology / Lens HET 7f:8m Fisher Exact Test framework 1.0000 Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Grip Strength / Forelimb grip strength normalised against body weight HET 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.019054 Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Combined SHIRPA and Dysmorphology / Head size HET 8f:8m Fisher Exact Test framework 1.0000 Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Combined SHIRPA and Dysmorphology / Coat - color pattern - back HET 8f:8m Fisher Exact Test framework 1.0000 Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Eye Morphology / Optic Disc HET 7f:8m Fisher Exact Test framework 1.0000 Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Open Field / Center average speed HET 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.24162 Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Eye Morphology / Narrow eye opening HET 7f:8m Fisher Exact Test framework 1.0000 Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Clinical Chemistry / Sodium HET 8f:8m Not processed 1.0000 FAILED - Insufficient variability in dependent variable 'IMPC_CBC_001_001' for MM/TF framework. Fisher Exact Test can be better way to do the analysis.
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Organ Weight / Heart weight HET 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.029004 Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Combined SHIRPA and Dysmorphology / Forepaw - shape HET 8f:8m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Body Composition (DEXA lean/fat) / Bone Mineral Content (excluding skull) HET 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.15534 Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Hematology / Neutrophil differential count HET 5f:4m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.15754 Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Hematology / Neutrophil differential count HET 3f:4m Not processed 1.0000 FAILED - Not enough data points in dependent variable 'IMPC_HEM_029_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Prostate HET f:m Supplied as data Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Prostate HET f:m Supplied as data Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Prostate HET f:m Supplied as data Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Prostate HET f:m Supplied as data Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Combined SHIRPA and Dysmorphology / Skin color - snout HET 8f:8m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Skin HET f:m Supplied as data Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Skin HET f:m Supplied as data Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Combined SHIRPA and Dysmorphology / Coat - hair texture / appearance - back HET 8f:8m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Lung HET f:m Supplied as data Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Lung HET f:m Supplied as data Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Lung HET f:m Supplied as data Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Lung HET f:m Supplied as data Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Clinical Chemistry / HDL-cholesterol HET 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.51089 Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Eye Morphology / Persistence of hyaloid vascular system HET 7f:8m Fisher Exact Test framework 1.0000 Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI2 HET 6f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.011588 Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI2 HET 2f:1m Not processed 1.0000 FAILED - Not enough mutant or control data
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - S HET 6f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 3.9283E-05 Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - S HET 2f:1m Not processed 1.0000 FAILED - Not enough mutant or control data
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Eye Morphology / Pupil Shape HET 7f:8m Fisher Exact Test framework 1.0000 Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Open Field / Periphery average speed HET 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 1.3366E-06 Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Fertility of Homozygous Knock-out Mice / Gross Findings Male HOM f:m Supplied as data Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Eye Morphology / Eye HET 7f:8m Fisher Exact Test framework 1.0000 Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell X-ray / Processes on vertebrae HET 6f:5m Fisher Exact Test framework 1.0000 Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell X-ray / Maxilla/Pre-maxilla HET 6f:5m Fisher Exact Test framework 0.0031930 Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Hematology / Lymphocyte differential count HET 5f:4m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.043034 Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Hematology / Lymphocyte differential count HET 3f:4m Not processed 1.0000 FAILED - Not enough data points in dependent variable 'IMPC_HEM_031_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Pancreas HET f:m Supplied as data Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Pancreas HET f:m Supplied as data Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Pancreas HET f:m Supplied as data Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Pancreas HET f:m Supplied as data Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Echo / Stroke Volume HET 6f:0m Mixed Model framework, linear mixed-effects model, equation withWeight 0.76233 Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Combined SHIRPA and Dysmorphology / Mouth morphology HET 8f:8m Fisher Exact Test framework 1.0000 Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Hematology / Monocyte differential count HET 5f:4m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.44531 Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Hematology / Monocyte differential count HET 3f:4m Not processed 1.0000 FAILED - Not enough data points in dependent variable 'IMPC_HEM_033_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Combined SHIRPA and Dysmorphology / Head bobbing HET 8f:8m Fisher Exact Test framework 1.0000 Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Spinal cord HET f:m Supplied as data Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Spinal cord HET f:m Supplied as data Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Spinal cord HET f:m Supplied as data Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Spinal cord HET f:m Supplied as data Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Body Composition (DEXA lean/fat) / Lean/Body weight HET 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.015051 Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell X-ray / Number of ribs right HET 6f:5m 1.0000 Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Combined SHIRPA and Dysmorphology / Skin texture - ear HET 8f:8m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Open Field / Distance travelled - total HET 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 5.8499E-07 Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Combined SHIRPA and Dysmorphology / Snout size HET 8f:8m Fisher Exact Test framework 1.0000 Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Clinical Chemistry / Alpha-amylase HET 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.00068466 Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Auditory Brain Stem Response / Click-evoked ABR threshold HET 2f:2m 1.0000 Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Eye Morphology / Synechia HET 7f:8m Fisher Exact Test framework 1.0000 Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Clinical Chemistry / Iron HET 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 9.1578E-05 Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Auditory Brain Stem Response / 24kHz-evoked ABR Threshold HET 2f:2m 1.0000 Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Clinical Chemistry / Total cholesterol HET 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.90884 Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Combined SHIRPA and Dysmorphology / Genitalia - size HET 8f:8m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Open Field / Periphery permanence time HET 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.036630 Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Clinical Chemistry / Albumin HET 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.00084373 Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Combined SHIRPA and Dysmorphology / Forelimb nail - length HET 8f:8m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Intraperitoneal glucose tolerance test (IPGTT) / Initial response to glucose challenge HET 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.45491 Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Echo / LVAWd HET 6f:0m Mixed Model framework, linear mixed-effects model, equation withWeight 0.30313 Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Combined SHIRPA and Dysmorphology / Aggression HET 8f:8m Fisher Exact Test framework 1.0000 Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Open Field / Number of center entries HET 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 1.6166E-06 Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell X-ray / Pelvis HET 6f:5m Fisher Exact Test framework 1.0000 Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Adrenal gland HET f:m Supplied as data Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Adrenal gland HET f:m Supplied as data Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Adrenal gland HET f:m Supplied as data Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Adrenal gland HET f:m Supplied as data Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Grip Strength / Forelimb grip strength measurement mean HET 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.20013 Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Combined SHIRPA and Dysmorphology / Hindlimbs - shape HET 8f:8m Fisher Exact Test framework 1.0000 Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Combined SHIRPA and Dysmorphology / Startle response HET 8f:8m Fisher Exact Test framework 1.0000 Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Urinary bladder HET f:m Supplied as data Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Urinary bladder HET f:m Supplied as data Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Urinary bladder HET f:m Supplied as data Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Urinary bladder HET f:m Supplied as data Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Eye Morphology / Eyelid morphology HET 7f:8m Fisher Exact Test framework 1.0000 Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Echo / LVPWs HET 6f:0m Mixed Model framework, linear mixed-effects model, equation withWeight 0.82755 Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Combined SHIRPA and Dysmorphology / Forelimb digit - shape HET 8f:8m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Gall bladder HET f:m Supplied as data Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Gall bladder HET f:m Supplied as data Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Gall bladder HET f:m Supplied as data Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Gall bladder HET f:m Supplied as data Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Hematology / Mean cell volume HET 5f:4m Mixed Model framework, linear mixed-effects model, equation withWeight 0.99739 Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Hematology / Mean cell volume HET 3f:4m Not processed 1.0000 FAILED - Not enough data points in dependent variable 'IMPC_HEM_005_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Combined SHIRPA and Dysmorphology / Coat - color - back HET 8f:8m Fisher Exact Test framework 1.0000 Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell X-ray / Femur HET 6f:5m Fisher Exact Test framework 1.0000 Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Eye Morphology / Cornea HET 7f:8m Fisher Exact Test framework 1.0000 Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Open Field / Center permanence time HET 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0085877 Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Auditory Brain Stem Response / 12kHz-evoked ABR Threshold HET 2f:2m 1.0000 Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Combined SHIRPA and Dysmorphology / Hindpaw - size HET 8f:8m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Hematology / Basophil cell count HET 5f:4m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.53756 Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Hematology / Basophil cell count HET 3f:4m Not processed 1.0000 FAILED - Not enough data points in dependent variable 'IMPC_HEM_037_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Body Composition (DEXA lean/fat) / Bone Mineral Density (excluding skull) HET 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.092533 Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Echo / Ejection Fraction HET 6f:0m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.031960 Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Combined SHIRPA and Dysmorphology / Upper lip morphology HET 8f:8m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Combined SHIRPA and Dysmorphology / Locomotor activity HET 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.00087866 Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Hematology / Red blood cell count HET 5f:4m Mixed Model framework, linear mixed-effects model, equation withWeight 0.027949 Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Hematology / Red blood cell count HET 3f:4m Not processed 1.0000 FAILED - Not enough data points in dependent variable 'IMPC_HEM_002_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Skeletal muscle HET f:m Supplied as data Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Skeletal muscle HET f:m Supplied as data Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Skeletal muscle HET f:m Supplied as data Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Skeletal muscle HET f:m Supplied as data Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Combined SHIRPA and Dysmorphology / Skin texture - tail HET 8f:8m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Combined SHIRPA and Dysmorphology / Vibrissae - appearance HET 8f:8m Fisher Exact Test framework 1.0000 Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Eye Morphology / Iris Pigmentation HET 7f:8m Fisher Exact Test framework 1.0000 Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI1 HET 6f:7m Mixed Model framework, generalized least squares, equation withoutWeight 0.21219 Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI1 HET 2f:1m Not processed 1.0000 FAILED - Not enough mutant or control data
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Eye Morphology / Retinal Blood Vessels HET 7f:8m Fisher Exact Test framework 1.0000 Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell X-ray / Mandibles HET 6f:5m Fisher Exact Test framework 1.0000 Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Hematology / Neutrophil cell count HET 5f:4m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.031071 Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Hematology / Neutrophil cell count HET 3f:4m Not processed 1.0000 FAILED - Not enough data points in dependent variable 'IMPC_HEM_030_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Seminal vesicle HET f:m Supplied as data Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Seminal vesicle HET f:m Supplied as data Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Seminal vesicle HET f:m Supplied as data Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Seminal vesicle HET f:m Supplied as data Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell X-ray / Humerus HET 6f:5m Fisher Exact Test framework 1.0000 Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Combined SHIRPA and Dysmorphology / Skin color - back paws HET 8f:8m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Large intestine HET f:m Supplied as data Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Large intestine HET f:m Supplied as data Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Large intestine HET f:m Supplied as data Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Large intestine HET f:m Supplied as data Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Combined SHIRPA and Dysmorphology / Limb grasp HET 8f:7m Fisher Exact Test framework 1.0000 Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Combined SHIRPA and Dysmorphology / Skin color - whole body HET 8f:8m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell X-ray / Number of digits HET 6f:5m 1.0000 Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Combined SHIRPA and Dysmorphology / Coat - hair distribution - abdomen HET 8f:8m Fisher Exact Test framework 1.0000 Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Clinical Chemistry / Urea (Blood Urea Nitrogen - BUN) HET 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 1.3372E-05 Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Combined SHIRPA and Dysmorphology / Coat - color pattern - head HET 8f:8m Fisher Exact Test framework 1.0000 Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Open Field / Periphery resting time HET 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 3.2954E-07 Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Combined SHIRPA and Dysmorphology / Genitalia - presence HET 8f:8m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Combined SHIRPA and Dysmorphology / Hindlimb nail - shape HET 8f:8m Fisher Exact Test framework 1.0000 Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell X-ray / Ulna HET 6f:5m Fisher Exact Test framework 1.0000 Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Combined SHIRPA and Dysmorphology / Coat - hair distribution - head HET 8f:8m Fisher Exact Test framework 1.0000 Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Uterus HET f:m Supplied as data Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Uterus HET f:m Supplied as data Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Uterus HET f:m Supplied as data Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Uterus HET f:m Supplied as data Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Organ Weight / Spleen weight HET 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.015431 Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Clinical Chemistry / Fructosamine HET 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.024685 Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Clinical Chemistry / Alkaline phosphatase HET 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.62401 Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Combined SHIRPA and Dysmorphology / Hindlimb digit - number HET 8f:8m Fisher Exact Test framework 1.0000 Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Stomach HET f:m Supplied as data Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Stomach HET f:m Supplied as data Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Stomach HET f:m Supplied as data Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Stomach HET f:m Supplied as data Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Combined SHIRPA and Dysmorphology / Tail - length HET 8f:8m Fisher Exact Test framework 0.037967 Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Eye Morphology / Eye Hemorrhage or Blood Presence HET 7f:8m Fisher Exact Test framework 1.0000 Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Hematology / Monocyte cell count HET 5f:4m Mixed Model framework, linear mixed-effects model, equation withWeight 0.68220 Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Hematology / Monocyte cell count HET 3f:4m Not processed 1.0000 FAILED - Not enough data points in dependent variable 'IMPC_HEM_034_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Combined SHIRPA and Dysmorphology / Unexpected behaviors HET 8f:8m Fisher Exact Test framework 1.0000 Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell X-ray / Teeth HET 6f:5m Fisher Exact Test framework 1.0000 Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - Global HET 6f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0022571 Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - Global HET 2f:1m Not processed 1.0000 FAILED - Not enough mutant or control data
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Echo / End-Systolic Diameter HET 6f:0m Mixed Model framework, linear mixed-effects model, equation withWeight 0.081995 Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell X-ray / Number of ribs left HET 6f:5m 1.0000 Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Combined SHIRPA and Dysmorphology / Hindlimbs - size HET 8f:8m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Combined SHIRPA and Dysmorphology / Skin texture - front paws HET 8f:8m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Body Composition (DEXA lean/fat) / Bone Area HET 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.00018371 Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Eye Morphology / Fusion between cornea and lens HET 7f:8m Fisher Exact Test framework 1.0000 Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Combined SHIRPA and Dysmorphology / Coat - color - head HET 8f:8m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Hematology / Mean corpuscular hemoglobin HET 5f:4m Mixed Model framework, linear mixed-effects model, equation withWeight 0.098930 Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Hematology / Mean corpuscular hemoglobin HET 3f:4m Not processed 1.0000 FAILED - Not enough data points in dependent variable 'IMPC_HEM_006_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Echo / LVIDs HET 6f:0m Mixed Model framework, linear mixed-effects model, equation withWeight 0.0069472 Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Echo / Cardiac Output HET 6f:0m Mixed Model framework, linear mixed-effects model, equation withWeight 0.64498 Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Combined SHIRPA and Dysmorphology / Hindlimb digit - shape HET 8f:8m Fisher Exact Test framework 1.0000 Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Intraperitoneal glucose tolerance test (IPGTT) / Fasted blood glucose concentration HET 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 5.1483E-13 Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Hematology / Large Unstained Cell (LUC) differential count HET 5f:4m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.020338 Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Hematology / Large Unstained Cell (LUC) differential count HET 3f:4m Not processed 1.0000 FAILED - Not enough data points in dependent variable 'IMPC_HEM_040_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Combined SHIRPA and Dysmorphology / Forepaw - size HET 8f:8m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Heart HET f:m Supplied as data Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Heart HET f:m Supplied as data Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Heart HET f:m Supplied as data Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Heart HET f:m Supplied as data Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Clinical Chemistry / Total bilirubin HET 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.067909 Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Combined SHIRPA and Dysmorphology / Forelimbs - position HET 8f:8m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell X-ray / Fusion of ribs HET 6f:5m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Body Composition (DEXA lean/fat) / BMC/Body weight HET 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 1.1264E-06 Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Combined SHIRPA and Dysmorphology / Lower lip morphology HET 8f:8m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Trachea HET f:m Supplied as data Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Trachea HET f:m Supplied as data Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Trachea HET f:m Supplied as data Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Trachea HET f:m Supplied as data Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Hematology / Basophil differential count HET 5f:4m Not processed 1.0000 FAILED - testDataset returned an error, check log file
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Hematology / Basophil differential count HET 3f:4m Not processed 1.0000 FAILED - Not enough data points in dependent variable 'IMPC_HEM_038_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Combined SHIRPA and Dysmorphology / Skin color - front paws HET 8f:8m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Testes HET f:m Supplied as data Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Testes HET f:m Supplied as data Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Testes HET f:m Supplied as data Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Testes HET f:m Supplied as data Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Combined SHIRPA and Dysmorphology / Coat - hair texture / appearance - abdomen HET 8f:8m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Open Field / Center resting time HET 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.53918 Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Clinical Chemistry / Glucose HET 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.16211 Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Eye Morphology / Retinal Blood Vessels Structure HET 7f:8m Fisher Exact Test framework 1.0000 Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Fertility of Homozygous Knock-out Mice / Gross Findings Female HOM f:m Supplied as data Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell X-ray / Joints HET 6f:5m Fisher Exact Test framework 1.0000 Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell X-ray / Skull shape HET 6f:5m Fisher Exact Test framework 1.0000 Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Echo / Fractional Shortening HET 6f:0m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.019666 Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Combined SHIRPA and Dysmorphology / Forelimb nail - number HET 8f:8m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Combined SHIRPA and Dysmorphology / Gait HET 8f:8m Fisher Exact Test framework 0.0068275 Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Kidney HET f:m Supplied as data Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Kidney HET f:m Supplied as data Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Kidney HET f:m Supplied as data Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Kidney HET f:m Supplied as data Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Hematology / Red blood cell distribution width HET 5f:4m Mixed Model framework, linear mixed-effects model, equation withWeight 0.00049549 Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Hematology / Red blood cell distribution width HET 3f:4m Not processed 1.0000 FAILED - Not enough data points in dependent variable 'IMPC_HEM_027_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Combined SHIRPA and Dysmorphology / Ears HET 8f:8m Fisher Exact Test framework 1.0000 Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Small intestine HET f:m Supplied as data Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Small intestine HET f:m Supplied as data Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Small intestine HET f:m Supplied as data Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Small intestine HET f:m Supplied as data Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Combined SHIRPA and Dysmorphology / Forelimb digit - number HET 8f:8m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Combined SHIRPA and Dysmorphology / Tail - presence HET 8f:8m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Clinical Chemistry / Chloride HET 8f:8m Not processed 1.0000 FAILED - Insufficient variability in dependent variable 'IMPC_CBC_003_001' for MM/TF framework. Fisher Exact Test can be better way to do the analysis.
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI4 HET 6f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.00092777 Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI4 HET 2f:1m Not processed 1.0000 FAILED - Not enough mutant or control data
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Body Composition (DEXA lean/fat) / Lean mass HET 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.20485 Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell X-ray / Tibia length HET 6f:5m Mixed Model framework, linear mixed-effects model, equation withWeight 0.36304 Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Eye Morphology / Pupil Light Response HET 7f:8m Fisher Exact Test framework 1.0000 Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Open Field / Whole arena average speed HET 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 6.0683E-07 Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Eye Morphology / Corneal opacity HET 7f:8m Fisher Exact Test framework 1.0000 Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Ovary HET f:m Supplied as data Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Ovary HET f:m Supplied as data Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Ovary HET f:m Supplied as data Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Ovary HET f:m Supplied as data Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Eye with optic nerve HET f:m Supplied as data Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Eye with optic nerve HET f:m Supplied as data Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Eye with optic nerve HET f:m Supplied as data Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Eye with optic nerve HET f:m Supplied as data Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Hematology / White blood cell count HET 5f:4m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.16860 Success
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Hematology / White blood cell count HET 3f:4m Not processed 1.0000 FAILED - Not enough data points in dependent variable 'IMPC_HEM_001_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Gnao1tm1b(EUCOMM)Hmgu MRC Harwell Combined SHIRPA and Dysmorphology / Skin color - tail HET 8f:8m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK

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