Apoeem1(IMPC)Bay
|
BCM
|
Open Field / Whole arena average speed series
|
HOM
|
28f:32m
|
|
|
NotProcessed |
Apoeem1(IMPC)Bay
|
BCM
|
Open Field / Center resting time series
|
HOM
|
28f:32m
|
|
|
NotProcessed |
Apoeem1(IMPC)Bay
|
BCM
|
Light-Dark Test / Time mobile light side
|
HOM
|
28f:32m
|
|
|
NotProcessed |
Apoeem1(IMPC)Bay
|
BCM
|
Open Field / Periphery resting time series
|
HOM
|
28f:32m
|
|
|
NotProcessed |
Apoeem1(IMPC)Bay
|
BCM
|
Open Field / Distance travelled - total
|
HOM
|
7f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.00250
|
Successful |
Apoeem1(IMPC)Bay
|
BCM
|
Open Field / Center average speed series
|
HOM
|
26f:32m
|
|
|
NotProcessed |
Apoeem1(IMPC)Bay
|
BCM
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP2
|
HOM
|
7f:8m
|
|
|
NotProcessed |
Apoeem1(IMPC)Bay
|
BCM
|
Open Field / Periphery permanence time
|
HOM
|
7f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.229
|
Successful |
Apoetm1Unc
|
WTSI
|
Acoustic Startle&PPI / BN startle magnitude
|
HOM
|
6f:12m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.453
|
Successful |
Apoetm1Unc
|
WTSI
|
Acoustic Startle&PPI / BN startle magnitude
|
HET
|
2f:11m
|
Linear Mixed Model framework, LME, not including Weight
|
0.823
|
Successful |
Apoeem1(IMPC)Bay
|
BCM
|
Open Field / Percentage center time
|
HOM
|
7f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.229
|
Successful |
Apoetm1Unc
|
WTSI
|
Open-field / Number of centre entries
|
HET
|
2f:11m
|
Linear Mixed Model framework, LME, including Weight
|
0.752
|
Successful |
Apoetm1Unc
|
WTSI
|
Open-field / Number of centre entries
|
HOM
|
6f:12m
|
Linear Mixed Model framework, LME, including Weight
|
0.894
|
Successful |
Apoetm1Unc
|
WTSI
|
Open-field / Latency to centre entry
|
HOM
|
6f:12m
|
Linear Mixed Model framework, LME, including Weight
|
0.833
|
Successful |
Apoetm1Unc
|
WTSI
|
Open-field / Latency to centre entry
|
HET
|
2f:11m
|
Linear Mixed Model framework, LME, not including Weight
|
0.886
|
Successful |
Apoetm1Unc
|
WTSI
|
Acoustic Startle&PPI / PP2 + pulse startle magnitude
|
HET
|
2f:11m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.265
|
Successful |
Apoetm1Unc
|
WTSI
|
Acoustic Startle&PPI / PP2 + pulse startle magnitude
|
HOM
|
6f:12m
|
Linear Model Using Generalized Least Squares framework, GLS, including Weight
|
0.326
|
Successful |
Apoetm1Unc
|
WTSI
|
Acoustic Startle&PPI / PP3 + pulse startle magnitude
|
HOM
|
6f:12m
|
Linear Model Using Generalized Least Squares framework, GLS, including Weight
|
0.123
|
Successful |
Apoetm1Unc
|
WTSI
|
Acoustic Startle&PPI / PP3 + pulse startle magnitude
|
HET
|
2f:11m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.538
|
Successful |
Apoeem1(IMPC)Bay
|
BCM
|
Open Field / Number of center entries
|
HOM
|
7f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.0703
|
Successful |
Apoetm1Unc
|
WTSI
|
Acoustic Startle&PPI / 110dB startle magnitude
|
HOM
|
6f:12m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.670
|
Successful |
Apoetm1Unc
|
WTSI
|
Acoustic Startle&PPI / 110dB startle magnitude
|
HET
|
2f:11m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.905
|
Successful |
Apoetm1Unc
|
WTSI
|
Acoustic Startle&PPI / PP1 + pulse startle magnitude
|
HOM
|
6f:12m
|
Linear Model Using Generalized Least Squares framework, GLS, including Weight
|
0.277
|
Successful |
Apoetm1Unc
|
WTSI
|
Acoustic Startle&PPI / PP1 + pulse startle magnitude
|
HET
|
2f:11m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.638
|
Successful |
Apoetm1Unc
|
WTSI
|
Acoustic Startle&PPI / PP3 startle magnitude
|
HET
|
2f:11m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.0854
|
Successful |
Apoetm1Unc
|
WTSI
|
Acoustic Startle&PPI / PP3 startle magnitude
|
HOM
|
6f:12m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.314
|
Successful |
Apoetm1Unc
|
WTSI
|
Acoustic Startle&PPI / PP4 startle magnitude
|
HET
|
2f:3m
|
|
|
NotProcessed |
Apoetm1Unc
|
WTSI
|
Acoustic Startle&PPI / PP4 startle magnitude
|
HOM
|
6f:6m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.757
|
Successful |
Apoeem1(IMPC)Bay
|
BCM
|
Light-Dark Test / Time mobile dark side
|
HOM
|
28f:32m
|
|
|
NotProcessed |
Apoetm1Unc
|
WTSI
|
Acoustic Startle&PPI / PP1 startle magnitude
|
HET
|
2f:11m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.276
|
Successful |
Apoetm1Unc
|
WTSI
|
Acoustic Startle&PPI / PP1 startle magnitude
|
HOM
|
6f:12m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.860
|
Successful |
Apoeem1(IMPC)Bay
|
BCM
|
Grip Strength / Forelimb grip strength measurement mean
|
HOM
|
7f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.312
|
Successful |
Apoetm1Unc
|
WTSI
|
Acoustic Startle&PPI / PP2 startle magnitude
|
HET
|
2f:11m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.208
|
Successful |
Apoetm1Unc
|
WTSI
|
Acoustic Startle&PPI / PP2 startle magnitude
|
HOM
|
6f:12m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.756
|
Successful |
Apoeem1(IMPC)Bay
|
BCM
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - BN
|
HOM
|
7f:8m
|
|
|
NotProcessed |
Apoeem1(IMPC)Bay
|
BCM
|
Open Field / Number of Rears
|
HOM
|
28f:32m
|
|
|
NotProcessed |
Apoeem1(IMPC)Bay
|
BCM
|
Open Field / Periphery distance travelled
|
HOM
|
7f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.00109
|
Successful |
Apoeem1(IMPC)Bay
|
BCM
|
Open Field / Center permanence time
|
HOM
|
7f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.229
|
Successful |
Apoeem1(IMPC)Bay
|
BCM
|
Grip Strength / Forelimb grip strength measurement
|
HOM
|
21f:24m
|
|
|
NotProcessed |
Apoetm1Unc
|
WTSI
|
Indirect ophthalmoscopy / Right optic disc
|
HOM
|
2f:7m
|
|
|
NotProcessed |
Apoetm1Unc
|
WTSI
|
Indirect ophthalmoscopy / Right optic disc
|
HET
|
f:8m
|
|
|
NotProcessed |
Apoeem1(IMPC)Bay
|
BCM
|
Light-Dark Test / Transition
|
HOM
|
7f:8m
|
|
|
NotProcessed |
Apoeem1(IMPC)Bay
|
BCM
|
Open Field / Percentage center movement time
|
HOM
|
7f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0600
|
Successful |
Apoeem1(IMPC)Bay
|
BCM
|
Open Field / Periphery permanence time series
|
HOM
|
28f:32m
|
|
|
NotProcessed |
Apoetm1Unc
|
WTSI
|
Grip-Strength / Forelimb grip strength measurement
|
HET
|
6f:33m
|
|
|
NotProcessed |
Apoetm1Unc
|
WTSI
|
Grip-Strength / Forelimb grip strength measurement
|
HOM
|
18f:36m
|
|
|
NotProcessed |
Apoetm1Unc
|
WTSI
|
Grip-Strength / Forelimb and hindlimb grip strength measurement
|
HOM
|
18f:36m
|
|
|
NotProcessed |
Apoetm1Unc
|
WTSI
|
Grip-Strength / Forelimb and hindlimb grip strength measurement
|
HET
|
6f:33m
|
|
|
NotProcessed |
Apoeem1(IMPC)Bay
|
BCM
|
Light-Dark Test / Percent time in dark
|
HOM
|
7f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.875
|
Successful |
Apoeem1(IMPC)Bay
|
BCM
|
Grip Strength / Forelimb and hindlimb grip strength normalised against body weight
|
HOM
|
7f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.981
|
Successful |
Apoeem1(IMPC)Bay
|
BCM
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP1_S
|
HOM
|
7f:8m
|
|
|
NotProcessed |
Apoeem1(IMPC)Bay
|
BCM
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI1
|
HOM
|
7f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.218
|
Successful |
Apoeem1(IMPC)Bay
|
BCM
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI3
|
HOM
|
7f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.840
|
Successful |
Apoetm1Unc
|
WTSI
|
Rotarod / Passive rotation
|
HOM
|
18f:36m
|
|
|
NotProcessed |
Apoetm1Unc
|
WTSI
|
Rotarod / Passive rotation
|
HET
|
6f:33m
|
|
|
NotProcessed |
Apoetm1Unc
|
WTSI
|
Rotarod / Latency to fall
|
HET
|
6f:33m
|
|
|
NotProcessed |
Apoetm1Unc
|
WTSI
|
Rotarod / Latency to fall
|
HOM
|
18f:36m
|
|
|
NotProcessed |
Apoetm1Unc
|
WTSI
|
Modified SHIRPA / Trunk curl
|
HOM
|
6f:12m
|
Fisher Exact Test framework
|
0.00339
|
Successful |
Apoetm1Unc
|
WTSI
|
Modified SHIRPA / Trunk curl
|
HET
|
2f:11m
|
Fisher Exact Test framework
|
0.552
|
Successful |
Apoetm1Unc
|
WTSI
|
Modified SHIRPA / Touch escape
|
HET
|
2f:11m
|
Fisher Exact Test framework
|
0.384
|
Successful |
Apoetm1Unc
|
WTSI
|
Modified SHIRPA / Touch escape
|
HOM
|
6f:12m
|
Fisher Exact Test framework
|
0.455
|
Successful |
Apoetm1Unc
|
WTSI
|
Modified SHIRPA / Startle response
|
HOM
|
6f:12m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Apoetm1Unc
|
WTSI
|
Modified SHIRPA / Startle response
|
HET
|
2f:11m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Apoetm1Unc
|
WTSI
|
Modified SHIRPA / Corneal reflex
|
HET
|
2f:11m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Apoetm1Unc
|
WTSI
|
Modified SHIRPA / Corneal reflex
|
HOM
|
6f:12m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Apoetm1Unc
|
WTSI
|
Modified SHIRPA / Pinna reflex
|
HOM
|
6f:12m
|
Fisher Exact Test framework
|
0.376
|
Successful |
Apoetm1Unc
|
WTSI
|
Modified SHIRPA / Pinna reflex
|
HET
|
2f:11m
|
Fisher Exact Test framework
|
0.607
|
Successful |
Apoetm1Unc
|
WTSI
|
Modified SHIRPA / Limb grasping
|
HET
|
2f:11m
|
|
|
NotProcessed |
Apoetm1Unc
|
WTSI
|
Modified SHIRPA / Limb grasping
|
HOM
|
6f:12m
|
Fisher Exact Test framework
|
0.0674
|
Successful |
Apoetm1Unc
|
WTSI
|
Modified SHIRPA / Vocalisation
|
HET
|
2f:11m
|
Fisher Exact Test framework
|
0.0204
|
Successful |
Apoetm1Unc
|
WTSI
|
Modified SHIRPA / Vocalisation
|
HOM
|
6f:12m
|
Fisher Exact Test framework
|
0.0210
|
Successful |
Apoetm1Unc
|
WTSI
|
Modified SHIRPA / Contact righting reflex
|
HOM
|
6f:12m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Apoetm1Unc
|
WTSI
|
Modified SHIRPA / Contact righting reflex
|
HET
|
2f:11m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Apoeem1(IMPC)Bay
|
BCM
|
Open Field / Center distance travelled
|
HOM
|
7f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.105
|
Successful |
Apoeem1(IMPC)Bay
|
BCM
|
Open Field / Center distance travelled series
|
HOM
|
28f:32m
|
|
|
NotProcessed |
Apoeem1(IMPC)Bay
|
BCM
|
Open Field / Whole arena resting time series
|
HOM
|
28f:32m
|
|
|
NotProcessed |
Apoeem1(IMPC)Bay
|
BCM
|
Open Field / Periphery resting time
|
HOM
|
7f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.0138
|
Successful |
Apoeem1(IMPC)Bay
|
BCM
|
Open Field / Center permanence time series
|
HOM
|
28f:32m
|
|
|
NotProcessed |
Apoeem1(IMPC)Bay
|
BCM
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP1
|
HOM
|
7f:8m
|
|
|
NotProcessed |
Apoetm1Unc
|
WTSI
|
Modified SHIRPA / Tremor
|
HOM
|
6f:12m
|
Fisher Exact Test framework
|
0.0461
|
Successful |
Apoetm1Unc
|
WTSI
|
Modified SHIRPA / Tremor
|
HET
|
2f:11m
|
Fisher Exact Test framework
|
0.146
|
Successful |
Apoetm1Unc
|
WTSI
|
Modified SHIRPA / Gait
|
HOM
|
6f:12m
|
Fisher Exact Test framework
|
0.211
|
Successful |
Apoetm1Unc
|
WTSI
|
Modified SHIRPA / Gait
|
HET
|
2f:11m
|
Fisher Exact Test framework
|
0.473
|
Successful |
Apoetm1Unc
|
WTSI
|
Modified SHIRPA / Locomotor activity
|
HOM
|
6f:12m
|
Linear Mixed Model framework, LME, including Weight
|
0.579
|
Successful |
Apoetm1Unc
|
WTSI
|
Modified SHIRPA / Locomotor activity
|
HET
|
2f:11m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.634
|
Successful |
Apoetm1Unc
|
WTSI
|
Modified SHIRPA / Transfer arousal
|
HET
|
2f:11m
|
Fisher Exact Test framework
|
0.0860
|
Successful |
Apoetm1Unc
|
WTSI
|
Modified SHIRPA / Transfer arousal
|
HOM
|
6f:12m
|
Fisher Exact Test framework
|
0.809
|
Successful |
Apoeem1(IMPC)Bay
|
BCM
|
Light-Dark Test / Light side time spent
|
HOM
|
28f:32m
|
|
|
NotProcessed |
Apoetm1Unc
|
WTSI
|
Acoustic Startle&PPI / Global prepulse inhibition
|
HET
|
2f:3m
|
|
|
NotProcessed |
Apoetm1Unc
|
WTSI
|
Acoustic Startle&PPI / Global prepulse inhibition
|
HOM
|
6f:6m
|
Linear Model Using Generalized Least Squares framework, GLS, including Weight
|
0.0339
|
Successful |
Apoetm1Unc
|
WTSI
|
Modified SHIRPA / Tail elevation
|
HET
|
2f:11m
|
Fisher Exact Test framework
|
0.154
|
Successful |
Apoetm1Unc
|
WTSI
|
Modified SHIRPA / Tail elevation
|
HOM
|
6f:12m
|
Fisher Exact Test framework
|
0.467
|
Successful |
Apoetm1Unc
|
WTSI
|
Acoustic Startle&PPI / Prepulse inhibition - PP3
|
HOM
|
6f:12m
|
Linear Model Using Generalized Least Squares framework, GLS, including Weight
|
0.00180
|
Successful |
Apoetm1Unc
|
WTSI
|
Acoustic Startle&PPI / Prepulse inhibition - PP3
|
HET
|
2f:11m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.313
|
Successful |
Apoetm1Unc
|
WTSI
|
Acoustic Startle&PPI / Prepulse inhibition - PP4
|
HET
|
2f:3m
|
|
|
NotProcessed |
Apoetm1Unc
|
WTSI
|
Acoustic Startle&PPI / Prepulse inhibition - PP4
|
HOM
|
6f:6m
|
Linear Model Using Generalized Least Squares framework, GLS, including Weight
|
0.0263
|
Successful |
Apoetm1Unc
|
WTSI
|
Grip-Strength / Forelimb grip strength measurement mean
|
HET
|
2f:11m
|
Linear Mixed Model framework, LME, including Weight
|
0.199
|
Successful |
Apoetm1Unc
|
WTSI
|
Grip-Strength / Forelimb grip strength measurement mean
|
HOM
|
6f:12m
|
Linear Mixed Model framework, LME, including Weight
|
0.991
|
Successful |
Apoetm1Unc
|
WTSI
|
Grip-Strength / Forelimb and hindlimb grip strength measurement mean
|
HET
|
2f:11m
|
Linear Mixed Model framework, LME, including Weight
|
0.109
|
Successful |
Apoetm1Unc
|
WTSI
|
Grip-Strength / Forelimb and hindlimb grip strength measurement mean
|
HOM
|
6f:12m
|
Linear Mixed Model framework, LME, including Weight
|
0.997
|
Successful |
Apoeem1(IMPC)Bay
|
BCM
|
Open Field / Number of rears - total
|
HOM
|
7f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.0384
|
Successful |
Apoetm1Unc
|
WTSI
|
Grip-Strength / Forelimb grip strength normalised against body weight
|
HET
|
2f:11m
|
Linear Mixed Model framework, LME, not including Weight
|
0.149
|
Successful |
Apoetm1Unc
|
WTSI
|
Grip-Strength / Forelimb grip strength normalised against body weight
|
HOM
|
6f:12m
|
Linear Mixed Model framework, LME, not including Weight
|
0.455
|
Successful |
Apoetm1Unc
|
WTSI
|
Grip-Strength / Forelimb and hindlimb grip strength normalised against body weight
|
HET
|
2f:11m
|
Linear Mixed Model framework, LME, not including Weight
|
0.106
|
Successful |
Apoetm1Unc
|
WTSI
|
Grip-Strength / Forelimb and hindlimb grip strength normalised against body weight
|
HOM
|
6f:12m
|
Linear Mixed Model framework, LME, not including Weight
|
0.584
|
Successful |
Apoeem1(IMPC)Bay
|
BCM
|
Open Field / Periphery distance travelled series
|
HOM
|
28f:32m
|
|
|
NotProcessed |
Apoeem1(IMPC)Bay
|
BCM
|
Open Field / Distance travelled
|
HOM
|
28f:32m
|
|
|
NotProcessed |
Apoetm1Unc
|
WTSI
|
Indirect ophthalmoscopy / Left optic disc
|
HOM
|
2f:8m
|
|
|
NotProcessed |
Apoetm1Unc
|
WTSI
|
Indirect ophthalmoscopy / Left optic disc
|
HET
|
f:8m
|
|
|
NotProcessed |
Apoeem1(IMPC)Bay
|
BCM
|
Open Field / Latency to center entry
|
HOM
|
7f:8m
|
Linear Model Using Generalized Least Squares framework, GLS, including Weight
|
0.417
|
Successful |
Apoeem1(IMPC)Bay
|
BCM
|
Open Field / Number of center entries series
|
HOM
|
28f:32m
|
|
|
NotProcessed |
Apoetm1Unc
|
WTSI
|
Modified SHIRPA / Body position
|
HOM
|
6f:12m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Apoetm1Unc
|
WTSI
|
Modified SHIRPA / Body position
|
HET
|
2f:11m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Apoeem1(IMPC)Bay
|
BCM
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP3_S
|
HOM
|
7f:8m
|
|
|
NotProcessed |
Apoetm1Unc
|
WTSI
|
Slit Lamp / Iris/pupil light response
|
HET
|
f:8m
|
|
|
NotProcessed |
Apoetm1Unc
|
WTSI
|
Slit Lamp / Iris/pupil light response
|
HOM
|
2f:8m
|
Fisher Exact Test framework
|
0.00425
|
Successful |
Apoeem1(IMPC)Bay
|
BCM
|
Light-Dark Test / Dark side time spent
|
HOM
|
28f:32m
|
|
|
NotProcessed |
Apoeem1(IMPC)Bay
|
BCM
|
Grip Strength / Forelimb and hindlimb grip strength measurement mean
|
HOM
|
7f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.790
|
Successful |
Apoetm1Unc
|
WTSI
|
Open-field / Periphery average speed
|
HOM
|
6f:12m
|
Linear Mixed Model framework, LME, including Weight
|
0.313
|
Successful |
Apoetm1Unc
|
WTSI
|
Open-field / Periphery average speed
|
HET
|
2f:11m
|
Linear Mixed Model framework, LME, not including Weight
|
0.834
|
Successful |
Apoetm1Unc
|
WTSI
|
Open-field / Periphery permanence time
|
HOM
|
6f:12m
|
Linear Mixed Model framework, LME, including Weight
|
0.285
|
Successful |
Apoetm1Unc
|
WTSI
|
Open-field / Periphery permanence time
|
HET
|
2f:11m
|
Linear Mixed Model framework, LME, including Weight
|
0.554
|
Successful |
Apoeem1(IMPC)Bay
|
BCM
|
Light-Dark Test / Percent time in light
|
HOM
|
7f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.875
|
Successful |
Apoetm1Unc
|
WTSI
|
Acoustic Startle&PPI / PP4 + pulse startle magnitude
|
HET
|
2f:3m
|
|
|
NotProcessed |
Apoetm1Unc
|
WTSI
|
Acoustic Startle&PPI / PP4 + pulse startle magnitude
|
HOM
|
6f:6m
|
Linear Mixed Model framework, LME, including Weight
|
0.748
|
Successful |
Apoetm1Unc
|
WTSI
|
Open-field / Periphery resting time
|
HET
|
2f:11m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0863
|
Successful |
Apoetm1Unc
|
WTSI
|
Open-field / Periphery resting time
|
HOM
|
6f:12m
|
Linear Mixed Model framework, LME, including Weight
|
0.953
|
Successful |
Apoetm1Unc
|
WTSI
|
Open-field / Periphery distance travelled
|
HOM
|
6f:12m
|
Linear Mixed Model framework, LME, including Weight
|
0.194
|
Successful |
Apoetm1Unc
|
WTSI
|
Open-field / Periphery distance travelled
|
HET
|
2f:11m
|
Linear Mixed Model framework, LME, including Weight
|
0.889
|
Successful |
Apoetm1Unc
|
WTSI
|
Open-field / Whole arena average speed
|
HOM
|
6f:12m
|
Linear Mixed Model framework, LME, including Weight
|
0.296
|
Successful |
Apoetm1Unc
|
WTSI
|
Open-field / Whole arena average speed
|
HET
|
2f:11m
|
Linear Mixed Model framework, LME, not including Weight
|
0.702
|
Successful |
Apoetm1Unc
|
WTSI
|
Open-field / Whole arena permanence time
|
HOM
|
6f:12m
|
|
|
NotProcessed |
Apoetm1Unc
|
WTSI
|
Open-field / Whole arena permanence time
|
HET
|
2f:11m
|
|
|
NotProcessed |
Apoeem1(IMPC)Bay
|
BCM
|
Open Field / Whole arena resting time
|
HOM
|
7f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.00171
|
Successful |
Apoetm1Unc
|
WTSI
|
Open-field / Whole arena resting time
|
HET
|
2f:11m
|
Linear Mixed Model framework, LME, not including Weight
|
0.134
|
Successful |
Apoetm1Unc
|
WTSI
|
Open-field / Whole arena resting time
|
HOM
|
6f:12m
|
Linear Mixed Model framework, LME, including Weight
|
0.376
|
Successful |
Apoeem1(IMPC)Bay
|
BCM
|
Grip Strength / Forelimb grip strength normalised against body weight
|
HOM
|
7f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.418
|
Successful |
Apoeem1(IMPC)Bay
|
BCM
|
Open Field / Center resting time
|
HOM
|
7f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.418
|
Successful |
Apoeem1(IMPC)Bay
|
BCM
|
Eye Morphology / Optic Disc
|
HOM
|
5f:4m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Apoeem1(IMPC)Bay
|
BCM
|
Eye Morphology / Optic Disc
|
HOM
|
2f:3m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Apoeem1(IMPC)Bay
|
BCM
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP2_S
|
HOM
|
7f:8m
|
|
|
NotProcessed |
Apoeem1(IMPC)Bay
|
BCM
|
Open Field / Center average speed
|
HOM
|
7f:8m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.714
|
Successful |
Apoeem1(IMPC)Bay
|
BCM
|
Grip Strength / Forelimb and hindlimb grip strength measurement
|
HOM
|
21f:24m
|
|
|
NotProcessed |
Apoetm1Unc
|
WTSI
|
Open-field / Centre average speed
|
HOM
|
6f:12m
|
Linear Mixed Model framework, LME, including Weight
|
0.221
|
Successful |
Apoetm1Unc
|
WTSI
|
Open-field / Centre average speed
|
HET
|
2f:11m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.635
|
Successful |
Apoetm1Unc
|
WTSI
|
Open-field / Centre permanence time
|
HOM
|
6f:12m
|
Linear Mixed Model framework, LME, including Weight
|
0.189
|
Successful |
Apoetm1Unc
|
WTSI
|
Open-field / Centre permanence time
|
HET
|
2f:11m
|
Linear Mixed Model framework, LME, including Weight
|
0.835
|
Successful |
Apoetm1Unc
|
WTSI
|
Open-field / Centre resting time
|
HOM
|
6f:12m
|
Linear Model Using Generalized Least Squares framework, GLS, including Weight
|
0.178
|
Successful |
Apoetm1Unc
|
WTSI
|
Open-field / Centre resting time
|
HET
|
2f:11m
|
Linear Model Using Generalized Least Squares framework, GLS, including Weight
|
0.830
|
Successful |
Apoetm1Unc
|
WTSI
|
Open-field / Centre distance travelled
|
HOM
|
6f:12m
|
Linear Mixed Model framework, LME, including Weight
|
0.847
|
Successful |
Apoetm1Unc
|
WTSI
|
Open-field / Centre distance travelled
|
HET
|
2f:11m
|
Linear Mixed Model framework, LME, including Weight
|
0.872
|
Successful |
Apoeem1(IMPC)Bay
|
BCM
|
Light-Dark Test / Latency to first transition into dark
|
HOM
|
7f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.935
|
Successful |
Apoeem1(IMPC)Bay
|
BCM
|
Light-Dark Test / Side changes
|
HOM
|
28f:32m
|
|
|
NotProcessed |
Apoetm1Unc
|
WTSI
|
Hot Plate / Time of first response
|
HOM
|
6f:12m
|
Linear Mixed Model framework, LME, not including Weight
|
0.398
|
Successful |
Apoetm1Unc
|
WTSI
|
Hot Plate / Time of first response
|
HET
|
2f:11m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.619
|
Successful |
Apoetm1Unc
|
WTSI
|
Hot Plate / Type of response
|
HET
|
2f:11m
|
|
|
NotProcessed |
Apoetm1Unc
|
WTSI
|
Hot Plate / Type of response
|
HOM
|
6f:12m
|
|
|
NotProcessed |
Apoeem1(IMPC)Bay
|
BCM
|
Open Field / Periphery average speed series
|
HOM
|
28f:32m
|
|
|
NotProcessed |
Apoetm1Unc
|
WTSI
|
Acoustic Startle&PPI / Prepulse inhibition - PP1
|
HOM
|
6f:12m
|
Linear Model Using Generalized Least Squares framework, GLS, including Weight
|
0.285
|
Successful |
Apoetm1Unc
|
WTSI
|
Acoustic Startle&PPI / Prepulse inhibition - PP1
|
HET
|
2f:11m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.455
|
Successful |
Apoetm1Unc
|
WTSI
|
Acoustic Startle&PPI / Prepulse inhibition - PP2
|
HET
|
2f:11m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.0799
|
Successful |
Apoetm1Unc
|
WTSI
|
Acoustic Startle&PPI / Prepulse inhibition - PP2
|
HOM
|
6f:12m
|
Linear Model Using Generalized Least Squares framework, GLS, including Weight
|
0.366
|
Successful |
Apoeem1(IMPC)Bay
|
BCM
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI2
|
HOM
|
7f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.343
|
Successful |
Apoeem1(IMPC)Bay
|
BCM
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - S
|
HOM
|
7f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.982
|
Successful |
Apoeem1(IMPC)Bay
|
BCM
|
Open Field / Periphery average speed
|
HOM
|
7f:8m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.192
|
Successful |
Apoeem1(IMPC)Bay
|
BCM
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP3
|
HOM
|
7f:8m
|
|
|
NotProcessed |
Apoetm1Unc
|
WTSI
|
Calorimetry / Total activity (no. of fine movement + no. of beam cuts)
|
HOM
|
738f:531m
|
|
|
NotProcessed |
Apoeem1(IMPC)Bay
|
BCM
|
Open Field / Whole arena average speed
|
HOM
|
7f:8m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.340
|
Successful |
Apoetm1Unc
|
WTSI
|
Calorimetry / Ambulatory activity (no. of beam cuts)
|
HOM
|
738f:531m
|
|
|
NotProcessed |
Apoetm1Unc
|
WTSI
|
Open-field / Number of rears
|
HOM
|
24f:48m
|
|
|
NotProcessed |
Apoetm1Unc
|
WTSI
|
Open-field / Number of rears
|
HET
|
8f:44m
|
|
|
NotProcessed |
Apoetm1Unc
|
WTSI
|
Open-field / Distance travelled
|
HOM
|
24f:48m
|
|
|
NotProcessed |
Apoetm1Unc
|
WTSI
|
Open-field / Distance travelled
|
HET
|
8f:44m
|
|
|
NotProcessed |