Adck5tm1.1(KOMP)Vlcg
|
JAX
|
Open Field - centre start / Whole arena average speed
|
HOM
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.000105
|
Successful |
Adck5tm1.1(KOMP)Vlcg
|
JAX
|
Electroconvulsive Threshold Testing / mA threshold inducing clonic seizure
|
HOM
|
4f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.527
|
Successful |
Adck5tm1.1(KOMP)Vlcg
|
JAX
|
Electroconvulsive Threshold Testing / mA threshold inducing clonic seizure
|
HOM
|
4f:m
|
Linear Mixed Model framework, LME, not including Weight
|
0.600
|
Successful |
Adck5tm1.1(KOMP)Vlcg
|
JAX
|
Hole-board Exploration / Holepoke sequence
|
HOM
|
236f:251m
|
|
|
NotProcessed |
Adck5tm1.1(KOMP)Vlcg
|
JAX
|
Sleep Wake / Light sleep bout lengths standard deviation
|
HOM
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.0135
|
Successful |
Adck5tm1.1(KOMP)Vlcg
|
JAX
|
Combined SHIRPA and Dysmorphology / Activity (body position)
|
HOM
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Adck5tm1.1(KOMP)Vlcg
|
JAX
|
Combined SHIRPA and Dysmorphology / Head bobbing
|
HOM
|
8f:8m
|
|
|
NotProcessed |
Adck5tm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP1
|
HOM
|
4f:5m
|
|
|
NotProcessed |
Adck5tm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP1
|
HOM
|
4f:3m
|
|
|
NotProcessed |
Adck5tm1.1(KOMP)Vlcg
|
JAX
|
Light-Dark Test / Percent time in light
|
HOM
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.278
|
Successful |
Adck5tm1.1(KOMP)Vlcg
|
JAX
|
Open Field - centre start / Center average speed
|
HOM
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.325
|
Successful |
Adck5tm1.1(KOMP)Vlcg
|
JAX
|
Combined SHIRPA and Dysmorphology / Trunk curl
|
HOM
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Adck5tm1.1(KOMP)Vlcg
|
JAX
|
Open Field - centre start / Center permanence time
|
HOM
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.440
|
Successful |
Adck5tm1.1(KOMP)Vlcg
|
JAX
|
Light-Dark Test / Side changes
|
HOM
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.215
|
Successful |
Adck5tm1.1(KOMP)Vlcg
|
JAX
|
Hole-board Exploration / Total holepokes
|
HOM
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.00119
|
Successful |
Adck5tm1.1(KOMP)Vlcg
|
JAX
|
Sleep Wake / Dark sleep bout lengths mean
|
HOM
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.992
|
Successful |
Adck5tm1.1(KOMP)Vlcg
|
JAX
|
Combined SHIRPA and Dysmorphology / Unexpected behaviors
|
HOM
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Adck5tm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP2
|
HOM
|
4f:5m
|
|
|
NotProcessed |
Adck5tm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP2
|
HOM
|
4f:3m
|
|
|
NotProcessed |
Adck5tm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - Global
|
HOM
|
4f:m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.315
|
Successful |
Adck5tm1.1(KOMP)Vlcg
|
JAX
|
Light-Dark Test / Light side time spent
|
HOM
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.317
|
Successful |
Adck5tm1.1(KOMP)Vlcg
|
JAX
|
Open Field - centre start / Periphery distance travelled
|
HOM
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.000491
|
Successful |
Adck5tm1.1(KOMP)Vlcg
|
JAX
|
Open Field - centre start / Whole arena resting time
|
HOM
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
9.55×10-05
|
Successful |
Adck5tm1.1(KOMP)Vlcg
|
JAX
|
Combined SHIRPA and Dysmorphology / Aggression
|
HOM
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Adck5tm1.1(KOMP)Vlcg
|
JAX
|
Open Field - centre start / Number of Rears
|
HOM
|
32f:32m
|
|
|
NotProcessed |
Adck5tm1.1(KOMP)Vlcg
|
JAX
|
Light-Dark Test / Time mobile light side
|
HOM
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.824
|
Successful |
Adck5tm1.1(KOMP)Vlcg
|
JAX
|
Grip Strength / Forelimb grip strength measurement mean
|
HOM
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.0905
|
Successful |
Adck5tm1.1(KOMP)Vlcg
|
JAX
|
Combined SHIRPA and Dysmorphology / Startle response
|
HOM
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Adck5tm1.1(KOMP)Vlcg
|
JAX
|
Sleep Wake / Breath rate during sleep standard deviation
|
HOM
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.420
|
Successful |
Adck5tm1.1(KOMP)Vlcg
|
JAX
|
Open Field - centre start / Percentage center time
|
HOM
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.440
|
Successful |
Adck5tm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - BN
|
HOM
|
4f:3m
|
|
|
NotProcessed |
Adck5tm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - BN
|
HOM
|
4f:5m
|
|
|
NotProcessed |
Adck5tm1.1(KOMP)Vlcg
|
JAX
|
Open Field - centre start / Distance travelled
|
HOM
|
32f:32m
|
|
|
NotProcessed |
Adck5tm1.1(KOMP)Vlcg
|
JAX
|
Combined SHIRPA and Dysmorphology / Vocalization
|
HOM
|
8f:8m
|
Fisher Exact Test framework
|
0.619
|
Successful |
Adck5tm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP3_S
|
HOM
|
4f:5m
|
|
|
NotProcessed |
Adck5tm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP3_S
|
HOM
|
4f:3m
|
|
|
NotProcessed |
Adck5tm1.1(KOMP)Vlcg
|
JAX
|
Sleep Wake / Sleep daily percent
|
HOM
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.168
|
Successful |
Adck5tm1.1(KOMP)Vlcg
|
JAX
|
Light-Dark Test / Dark side time spent
|
HOM
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.317
|
Successful |
Adck5tm1.1(KOMP)Vlcg
|
JAX
|
Grip Strength / Forelimb and hindlimb grip strength measurement mean
|
HOM
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.470
|
Successful |
Adck5tm1.1(KOMP)Vlcg
|
JAX
|
Sleep Wake / Sleep light phase percent
|
HOM
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.0925
|
Successful |
Adck5tm1.1(KOMP)Vlcg
|
JAX
|
Open Field - centre start / Number of rears - total
|
HOM
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.351
|
Successful |
Adck5tm1.1(KOMP)Vlcg
|
JAX
|
Grip Strength / Forelimb grip strength measurement
|
HOM
|
24f:24m
|
|
|
NotProcessed |
Adck5tm1.1(KOMP)Vlcg
|
JAX
|
Rotarod / Latency to fall
|
HOM
|
40f:40m
|
|
|
NotProcessed |
Adck5tm1.1(KOMP)Vlcg
|
JAX
|
Sleep Wake / Peak wake with respect to dark onset median
|
HOM
|
8f:8m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.316
|
Successful |
Adck5tm1.1(KOMP)Vlcg
|
JAX
|
Grip Strength / Forelimb grip strength normalised against body weight
|
HOM
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0431
|
Successful |
Adck5tm1.1(KOMP)Vlcg
|
JAX
|
Combined SHIRPA and Dysmorphology / Locomotor activity
|
HOM
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0792
|
Successful |
Adck5tm1.1(KOMP)Vlcg
|
JAX
|
Eye Morphology / Optic Disc
|
HOM
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Adck5tm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP2_S
|
HOM
|
4f:3m
|
|
|
NotProcessed |
Adck5tm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP2_S
|
HOM
|
4f:5m
|
|
|
NotProcessed |
Adck5tm1.1(KOMP)Vlcg
|
JAX
|
Combined SHIRPA and Dysmorphology / Tail elevation
|
HOM
|
8f:8m
|
|
|
NotProcessed |
Adck5tm1.1(KOMP)Vlcg
|
JAX
|
Open Field - centre start / Periphery average speed
|
HOM
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.000137
|
Successful |
Adck5tm1.1(KOMP)Vlcg
|
JAX
|
Light-Dark Test / Time mobile dark side
|
HOM
|
8f:8m
|
Linear Model Using Generalized Least Squares framework, GLS, including Weight
|
0.359
|
Successful |
Adck5tm1.1(KOMP)Vlcg
|
JAX
|
Light-Dark Test / Fecal boli
|
HOM
|
8f:8m
|
Linear Model Using Generalized Least Squares framework, GLS, including Weight
|
0.102
|
Successful |
Adck5tm1.1(KOMP)Vlcg
|
JAX
|
Combined SHIRPA and Dysmorphology / Contact righting
|
HOM
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Adck5tm1.1(KOMP)Vlcg
|
JAX
|
Sleep Wake / Sleep dark phase percent
|
HOM
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.0970
|
Successful |
Adck5tm1.1(KOMP)Vlcg
|
JAX
|
Grip Strength / Forelimb and hindlimb grip strength normalised against body weight
|
HOM
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.446
|
Successful |
Adck5tm1.1(KOMP)Vlcg
|
JAX
|
Grip Strength / Forelimb and hindlimb grip strength measurement
|
HOM
|
24f:24m
|
|
|
NotProcessed |
Adck5tm1.1(KOMP)Vlcg
|
JAX
|
Open Field - centre start / Distance travelled - total
|
HOM
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.000110
|
Successful |
Adck5tm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP1_S
|
HOM
|
4f:3m
|
|
|
NotProcessed |
Adck5tm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP1_S
|
HOM
|
4f:5m
|
|
|
NotProcessed |
Adck5tm1.1(KOMP)Vlcg
|
JAX
|
Open Field - centre start / Periphery permanence time
|
HOM
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.441
|
Successful |
Adck5tm1.1(KOMP)Vlcg
|
JAX
|
Sleep Wake / Breath rate during sleep mean
|
HOM
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.689
|
Successful |
Adck5tm1.1(KOMP)Vlcg
|
JAX
|
Combined SHIRPA and Dysmorphology / Gait
|
HOM
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Adck5tm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI1
|
HOM
|
4f:3m
|
Linear Mixed Model framework, LME, not including Weight
|
0.223
|
Successful |
Adck5tm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI1
|
HOM
|
4f:5m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.625
|
Successful |
Adck5tm1.1(KOMP)Vlcg
|
JAX
|
Rotarod / Learning slope
|
HOM
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.668
|
Successful |
Adck5tm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI3
|
HOM
|
4f:5m
|
Linear Mixed Model framework, LME, not including Weight
|
0.157
|
Successful |
Adck5tm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI3
|
HOM
|
4f:3m
|
Linear Mixed Model framework, LME, including Weight
|
0.326
|
Successful |
Adck5tm1.1(KOMP)Vlcg
|
JAX
|
Sleep Wake / Sleep bout lengths mean
|
HOM
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.804
|
Successful |
Adck5tm1.1(KOMP)Vlcg
|
JAX
|
Combined SHIRPA and Dysmorphology / Tremor
|
HOM
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Adck5tm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI2
|
HOM
|
4f:5m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0679
|
Successful |
Adck5tm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI2
|
HOM
|
4f:3m
|
Linear Mixed Model framework, LME, not including Weight
|
0.419
|
Successful |
Adck5tm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - S
|
HOM
|
4f:5m
|
Linear Mixed Model framework, LME, not including Weight
|
0.192
|
Successful |
Adck5tm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - S
|
HOM
|
4f:3m
|
Linear Mixed Model framework, LME, including Weight
|
0.781
|
Successful |
Adck5tm1.1(KOMP)Vlcg
|
JAX
|
Light-Dark Test / Latency to first transition into dark
|
HOM
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.979
|
Successful |
Adck5tm1.1(KOMP)Vlcg
|
JAX
|
Rotarod / Learning difference
|
HOM
|
8f:8m
|
Linear Model Using Generalized Least Squares framework, GLS, including Weight
|
0.925
|
Successful |
Adck5tm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP3
|
HOM
|
4f:3m
|
|
|
NotProcessed |
Adck5tm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP3
|
HOM
|
4f:5m
|
|
|
NotProcessed |
Adck5tm1.1(KOMP)Vlcg
|
JAX
|
Combined SHIRPA and Dysmorphology / Limb grasp
|
HOM
|
8f:8m
|
Fisher Exact Test framework
|
0.0132
|
Successful |
Adck5tm1.1(KOMP)Vlcg
|
JAX
|
Sleep Wake / Dark sleep bout lengths standard deviation
|
HOM
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.612
|
Successful |
Adck5tm1.1(KOMP)Vlcg
|
JAX
|
Eye Morphology / Pupil Light Response
|
HOM
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Adck5tm1.1(KOMP)Vlcg
|
JAX
|
Sleep Wake / Light sleep bout lengths mean
|
HOM
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.594
|
Successful |
Adck5tm1.1(KOMP)Vlcg
|
JAX
|
Combined SHIRPA and Dysmorphology / Transfer arousal
|
HOM
|
8f:8m
|
|
|
NotProcessed |
Adck5tm1.1(KOMP)Vlcg
|
JAX
|
Sleep Wake / Sleep bout lengths standard deviation
|
HOM
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.0518
|
Successful |
Adck5tm1.1(KOMP)Vlcg
|
JAX
|
Light-Dark Test / Percent time in dark
|
HOM
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.278
|
Successful |
Adck5tm1.1(KOMP)Vlcg
|
JAX
|
Rotarod / Average duration
|
HOM
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.760
|
Successful |
Adck5tm1.1(KOMP)Vlcg
|
JAX
|
Open Field - centre start / Center distance travelled
|
HOM
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.00616
|
Successful |