All nervous system phenotype, behavior/neurological phenotype data for Gipc3

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Allele Center Procedure / Parameter Zygosity Mutants Statistical
Method
P Value Status Graph
Gipc3tm1b(KOMP)Wtsi JAX Electroconvulsive Threshold Testing / mA threshold inducing clonic seizure HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.054524 Success
Gipc3tm1b(KOMP)Wtsi JAX Sleep Wake / Light sleep bout lengths standard deviation HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.0059532 Success
Gipc3tm1b(KOMP)Wtsi JAX Combined SHIRPA and Dysmorphology / Activity (body position) HOM 8f:10m Fisher Exact Test framework 1.0000 Success
Gipc3tm1b(KOMP)Wtsi JAX Combined SHIRPA and Dysmorphology / Head bobbing HOM 8f:10m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Gipc3tm1b(KOMP)Wtsi JAX Light-Dark Test / Percent time in light HOM 8f:10m Mixed Model framework, linear mixed-effects model, equation withWeight 0.43289 Success
Gipc3tm1b(KOMP)Wtsi JAX Combined SHIRPA and Dysmorphology / Trunk curl HOM 8f:10m Fisher Exact Test framework 1.0000 Success
Gipc3tm1b(KOMP)Wtsi JAX Gross Pathology and Tissue Collection / Spinal cord HOM f:m Supplied as data Success
Gipc3tm1b(KOMP)Wtsi JAX Light-Dark Test / Side changes HOM 8f:10m Mixed Model framework, linear mixed-effects model, equation withWeight 0.89937 Success
Gipc3tm1b(KOMP)Wtsi JAX Hole-board Exploration / Total holepokes HOM 8f:10m Mixed Model framework, linear mixed-effects model, equation withWeight 0.11967 Success
Gipc3tm1b(KOMP)Wtsi JAX Open Field / Distance travelled - total HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.43172 Success
Gipc3tm1b(KOMP)Wtsi JAX Sleep Wake / Dark sleep bout lengths mean HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.31358 Success
Gipc3tm1b(KOMP)Wtsi JAX Open Field / Number of rears - total HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.95563 Success
Gipc3tm1b(KOMP)Wtsi JAX Combined SHIRPA and Dysmorphology / Unexpected behaviors HOM 8f:10m Fisher Exact Test framework 1.0000 Success
Gipc3tm1b(KOMP)Wtsi JAX Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - Global HOM 8f:4m Mixed Model framework, linear mixed-effects model, equation withWeight 0.0059596 Success
Gipc3tm1b(KOMP)Wtsi JAX Light-Dark Test / Light side time spent HOM 8f:10m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.20975 Success
Gipc3tm1b(KOMP)Wtsi JAX Open Field / Periphery permanence time HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.70977 Success
Gipc3tm1b(KOMP)Wtsi JAX Open Field / Percentage center time HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.70907 Success
Gipc3tm1b(KOMP)Wtsi JAX Combined SHIRPA and Dysmorphology / Aggression HOM 8f:10m Fisher Exact Test framework 1.0000 Success
Gipc3tm1b(KOMP)Wtsi JAX Light-Dark Test / Time mobile light side HOM 8f:10m Mixed Model framework, linear mixed-effects model, equation withWeight 0.52717 Success
Gipc3tm1b(KOMP)Wtsi JAX Grip Strength / Forelimb grip strength measurement mean HOM 8f:10m Mixed Model framework, linear mixed-effects model, equation withWeight 0.56871 Success
Gipc3tm1b(KOMP)Wtsi JAX Combined SHIRPA and Dysmorphology / Startle response HOM 8f:10m Fisher Exact Test framework 1.0000 Success
Gipc3tm1b(KOMP)Wtsi JAX Sleep Wake / Breath rate during sleep standard deviation HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.17353 Success
Gipc3tm1b(KOMP)Wtsi JAX Combined SHIRPA and Dysmorphology / Vocalization HOM 8f:10m Fisher Exact Test framework 1.0000 Success
Gipc3tm1b(KOMP)Wtsi JAX Tail Suspension / Time immobile HOM 8f:6m Mixed Model framework, linear mixed-effects model, equation withWeight 0.13874 Success
Gipc3tm1b(KOMP)Wtsi JAX Open Field / Periphery distance travelled HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.31856 Success
Gipc3tm1b(KOMP)Wtsi JAX Sleep Wake / Sleep daily percent HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.85275 Success
Gipc3tm1b(KOMP)Wtsi JAX Light-Dark Test / Dark side time spent HOM 8f:10m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.20975 Success
Gipc3tm1b(KOMP)Wtsi JAX Grip Strength / Forelimb and hindlimb grip strength measurement mean HOM 8f:10m Mixed Model framework, linear mixed-effects model, equation withWeight 0.80166 Success
Gipc3tm1b(KOMP)Wtsi JAX Sleep Wake / Sleep light phase percent HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.019017 Success
Gipc3tm1b(KOMP)Wtsi JAX Open Field / Center permanence time HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.70907 Success
Gipc3tm1b(KOMP)Wtsi JAX Open Field / Whole arena resting time HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.24878 Success
Gipc3tm1b(KOMP)Wtsi JAX Tail Suspension / Latency to immobility HOM 8f:6m Mixed Model framework, linear mixed-effects model, equation withWeight 0.033843 Success
Gipc3tm1b(KOMP)Wtsi JAX Sleep Wake / Peak wake with respect to dark onset median HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.32753 Success
Gipc3tm1b(KOMP)Wtsi JAX Combined SHIRPA and Dysmorphology / Locomotor activity HOM 8f:10m Mixed Model framework, linear mixed-effects model, equation withWeight 0.032303 Success
Gipc3tm1b(KOMP)Wtsi JAX Eye Morphology / Optic Disc HOM 8f:8m Fisher Exact Test framework 1.0000 Success
Gipc3tm1b(KOMP)Wtsi JAX Light-Dark Test / Time mobile dark side HOM 8f:10m Mixed Model framework, linear mixed-effects model, equation withWeight 0.050276 Success
Gipc3tm1b(KOMP)Wtsi JAX Open Field / Center average speed HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.12852 Success
Gipc3tm1b(KOMP)Wtsi JAX Light-Dark Test / Fecal boli HOM 8f:10m Mixed Model framework, linear mixed-effects model, equation withWeight 0.73426 Success
Gipc3tm1b(KOMP)Wtsi JAX Combined SHIRPA and Dysmorphology / Contact righting HOM 8f:10m Fisher Exact Test framework 1.0000 Success
Gipc3tm1b(KOMP)Wtsi JAX Sleep Wake / Sleep dark phase percent HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.11418 Success
Gipc3tm1b(KOMP)Wtsi JAX Tail Suspension / Climbing HOM 8f:6m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Gipc3tm1b(KOMP)Wtsi JAX Sleep Wake / Breath rate during sleep mean HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.050398 Success
Gipc3tm1b(KOMP)Wtsi JAX Combined SHIRPA and Dysmorphology / Gait HOM 8f:10m Fisher Exact Test framework 1.0000 Success
Gipc3tm1b(KOMP)Wtsi JAX Rotarod / Learning slope HOM 8f:9m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.00079801 Success
Gipc3tm1b(KOMP)Wtsi JAX Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI1 HOM 8f:4m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.018639 Success
Gipc3tm1b(KOMP)Wtsi JAX Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI1 HOM 0f:6m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.90007 Success
Gipc3tm1b(KOMP)Wtsi JAX Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI3 HOM 0f:6m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.29632 Success
Gipc3tm1b(KOMP)Wtsi JAX Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI3 HOM 8f:4m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.56361 Success
Gipc3tm1b(KOMP)Wtsi JAX Sleep Wake / Sleep bout lengths mean HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.050789 Success
Gipc3tm1b(KOMP)Wtsi JAX Combined SHIRPA and Dysmorphology / Tremor HOM 8f:10m Fisher Exact Test framework 1.0000 Success
Gipc3tm1b(KOMP)Wtsi JAX Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI2 HOM 8f:4m Mixed Model framework, linear mixed-effects model, equation withoutWeight 7.8201E-05 Success
Gipc3tm1b(KOMP)Wtsi JAX Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI2 HOM 0f:6m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.16412 Success
Gipc3tm1b(KOMP)Wtsi JAX Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - S HOM 8f:4m Mixed Model framework, linear mixed-effects model, equation withoutWeight 8.5630E-11 Success
Gipc3tm1b(KOMP)Wtsi JAX Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - S HOM 0f:6m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.00021304 Success
Gipc3tm1b(KOMP)Wtsi JAX Light-Dark Test / Latency to first transition into dark HOM 8f:10m Mixed Model framework, linear mixed-effects model, equation withWeight 0.38999 Success
Gipc3tm1b(KOMP)Wtsi JAX Rotarod / Learning difference HOM 8f:9m Mixed Model framework, generalized least squares, equation withoutWeight 0.012291 Success
Gipc3tm1b(KOMP)Wtsi JAX Open Field / Periphery average speed HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.35340 Success
Gipc3tm1b(KOMP)Wtsi JAX Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI4 HOM 8f:4m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.18462 Success
Gipc3tm1b(KOMP)Wtsi JAX Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI4 HOM 0f:3m Not processed 1.0000 FAILED - Not enough mutant measurements (0f/3m)
Gipc3tm1b(KOMP)Wtsi JAX Sleep Wake / Dark sleep bout lengths standard deviation HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.53422 Success
Gipc3tm1b(KOMP)Wtsi JAX Combined SHIRPA and Dysmorphology / Limb grasp HOM 8f:10m Fisher Exact Test framework 1.0000 Success
Gipc3tm1b(KOMP)Wtsi JAX Eye Morphology / Pupil Light Response HOM 8f:8m Fisher Exact Test framework 1.0000 Success
Gipc3tm1b(KOMP)Wtsi JAX Open Field / Whole arena average speed HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.43036 Success
Gipc3tm1b(KOMP)Wtsi JAX Sleep Wake / Light sleep bout lengths mean HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0023682 Success
Gipc3tm1b(KOMP)Wtsi JAX Sleep Wake / Sleep bout lengths standard deviation HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.011680 Success
Gipc3tm1b(KOMP)Wtsi JAX Open Field / Center distance travelled HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.68149 Success
Gipc3tm1b(KOMP)Wtsi JAX Light-Dark Test / Percent time in dark HOM 8f:10m Mixed Model framework, linear mixed-effects model, equation withWeight 0.43289 Success
Gipc3tm1b(KOMP)Wtsi JAX Sleep Wake / Activity onset with respect to dark onset median HOM 6f:3m Not processed 1.0000 FAILED - Not enough data points in dependent variable 'JAX_SLW_011_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.

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