Lyplal1tm1a(KOMP)Wtsi
|
WTSI
|
Clinical Chemistry / Free fatty acids
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.179
|
Successful |
Lyplal1tm1b(KOMP)Wtsi
|
UC Davis
|
Clinical Chemistry / Alanine aminotransferase
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0609
|
Successful |
Lyplal1tm1b(KOMP)Wtsi
|
MRC Harwell
|
Clinical Chemistry / Alanine aminotransferase
|
HOM
|
8f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.376
|
Successful |
Lyplal1tm1a(KOMP)Wtsi
|
WTSI
|
Clinical Chemistry / Alanine aminotransferase
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.742
|
Successful |
Lyplal1tm1b(KOMP)Wtsi
|
UC Davis
|
Indirect Calorimetry / Heat production (metabolic rate)
|
HOM
|
f:81m
|
|
|
NotProcessed |
Lyplal1tm1b(KOMP)Wtsi
|
MRC Harwell
|
Indirect Calorimetry / Heat production (metabolic rate)
|
HOM
|
f:497m
|
|
|
NotProcessed |
Lyplal1tm1a(KOMP)Wtsi
|
WTSI
|
Indirect Calorimetry / Heat production (metabolic rate)
|
HOM
|
f:158m
|
|
|
NotProcessed |
Lyplal1tm1b(KOMP)Wtsi
|
UC Davis
|
Clinical Chemistry / Calcium
|
HOM
|
7f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.453
|
Successful |
Lyplal1tm1a(KOMP)Wtsi
|
WTSI
|
Clinical Chemistry / Calcium
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.534
|
Successful |
Lyplal1tm1b(KOMP)Wtsi
|
MRC Harwell
|
Clinical Chemistry / Calcium
|
HOM
|
8f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.640
|
Successful |
Lyplal1tm1a(KOMP)Wtsi
|
WTSI
|
Clinical Chemistry / Creatinine
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0398
|
Successful |
Lyplal1tm1b(KOMP)Wtsi
|
MRC Harwell
|
Clinical Chemistry / Creatinine
|
HOM
|
8f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.734
|
Successful |
Lyplal1tm1b(KOMP)Wtsi
|
UC Davis
|
Clinical Chemistry / Creatinine
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.896
|
Successful |
Lyplal1tm1a(KOMP)Wtsi
|
WTSI
|
Clinical Chemistry / Glucose
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.0190
|
Successful |
Lyplal1tm1b(KOMP)Wtsi
|
MRC Harwell
|
Clinical Chemistry / Glucose
|
HOM
|
8f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.928
|
Successful |
Lyplal1tm1b(KOMP)Wtsi
|
UC Davis
|
Clinical Chemistry / Glucose
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.994
|
Successful |
Lyplal1tm1b(KOMP)Wtsi
|
MRC Harwell
|
Clinical Chemistry / Fructosamine
|
HOM
|
8f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0885
|
Successful |
Lyplal1tm1a(KOMP)Wtsi
|
WTSI
|
Clinical Chemistry / Fructosamine
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.199
|
Successful |
Lyplal1tm1b(KOMP)Wtsi
|
MRC Harwell
|
Clinical Chemistry / Sodium
|
HOM
|
8f:7m
|
|
|
NotProcessed |
Lyplal1tm1a(KOMP)Wtsi
|
WTSI
|
Clinical Chemistry / Sodium
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.00251
|
Successful |
Lyplal1tm1a(KOMP)Wtsi
|
WTSI
|
Clinical Chemistry / Alkaline phosphatase
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
4.54×10-07
|
Successful |
Lyplal1tm1b(KOMP)Wtsi
|
UC Davis
|
Clinical Chemistry / Alkaline phosphatase
|
HOM
|
7f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0707
|
Successful |
Lyplal1tm1b(KOMP)Wtsi
|
MRC Harwell
|
Clinical Chemistry / Alkaline phosphatase
|
HOM
|
8f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.424
|
Successful |
Lyplal1tm1a(KOMP)Wtsi
|
WTSI
|
Clinical Chemistry / Glycerol
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.0807
|
Successful |
Lyplal1tm1b(KOMP)Wtsi
|
MRC Harwell
|
Clinical Chemistry / Alpha-amylase
|
HOM
|
8f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.254
|
Successful |
Lyplal1tm1a(KOMP)Wtsi
|
WTSI
|
Clinical Chemistry / Alpha-amylase
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.683
|
Successful |
Lyplal1tm1b(KOMP)Wtsi
|
MRC Harwell
|
Clinical Chemistry / Iron
|
HOM
|
8f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.000205
|
Successful |
Lyplal1tm1a(KOMP)Wtsi
|
WTSI
|
Clinical Chemistry / Iron
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.245
|
Successful |
Lyplal1tm1a(KOMP)Wtsi
|
WTSI
|
Clinical Chemistry / Magnesium
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.337
|
Successful |
Lyplal1tm1b(KOMP)Wtsi
|
UC Davis
|
Intraperitoneal glucose tolerance test (IPGTT) / Area under glucose response curve
|
HOM
|
10f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0527
|
Successful |
Lyplal1tm1a(KOMP)Wtsi
|
WTSI
|
Intraperitoneal glucose tolerance test (IPGTT) / Area under glucose response curve
|
HOM
|
8f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.411
|
Successful |
Lyplal1tm1b(KOMP)Wtsi
|
MRC Harwell
|
Intraperitoneal glucose tolerance test (IPGTT) / Area under glucose response curve
|
HOM
|
8f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.798
|
Successful |
Lyplal1tm1a(KOMP)Wtsi
|
WTSI
|
Clinical Chemistry / Creatine kinase
|
HOM
|
7f:6m
|
Linear Mixed Model framework, LME, including Weight
|
0.169
|
Successful |
Lyplal1tm1b(KOMP)Wtsi
|
MRC Harwell
|
Clinical Chemistry / Creatine kinase
|
HOM
|
8f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.920
|
Successful |
Lyplal1tm1b(KOMP)Wtsi
|
MRC Harwell
|
Clinical Chemistry / Total cholesterol
|
HOM
|
8f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.0829
|
Successful |
Lyplal1tm1b(KOMP)Wtsi
|
UC Davis
|
Clinical Chemistry / Total cholesterol
|
HOM
|
7f:7m
|
Linear Model Using Generalized Least Squares framework, GLS, including Weight
|
0.344
|
Successful |
Lyplal1tm1a(KOMP)Wtsi
|
WTSI
|
Clinical Chemistry / Total cholesterol
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.362
|
Successful |
Lyplal1tm1a(KOMP)Wtsi
|
WTSI
|
Clinical Chemistry / Total protein
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0554
|
Successful |
Lyplal1tm1b(KOMP)Wtsi
|
MRC Harwell
|
Clinical Chemistry / Total protein
|
HOM
|
8f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.883
|
Successful |
Lyplal1tm1b(KOMP)Wtsi
|
UC Davis
|
Clinical Chemistry / Total protein
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.955
|
Successful |
Lyplal1tm1b(KOMP)Wtsi
|
UC Davis
|
Clinical Chemistry / Cholesterol ratio
|
HOM
|
5f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.173
|
Successful |
Lyplal1tm1b(KOMP)Wtsi
|
UC Davis
|
Body Composition (DEXA lean/fat) / Fat/Body weight
|
HOM
|
10f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0512
|
Successful |
Lyplal1tm1a(KOMP)Wtsi
|
WTSI
|
Body Composition (DEXA lean/fat) / Fat/Body weight
|
HOM
|
8f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.921
|
Successful |
Lyplal1tm1b(KOMP)Wtsi
|
UC Davis
|
Indirect Calorimetry / Oxygen consumption
|
HOM
|
f:81m
|
|
|
NotProcessed |
Lyplal1tm1a(KOMP)Wtsi
|
WTSI
|
Indirect Calorimetry / Oxygen consumption
|
HOM
|
f:158m
|
|
|
NotProcessed |
Lyplal1tm1b(KOMP)Wtsi
|
MRC Harwell
|
Indirect Calorimetry / Oxygen consumption
|
HOM
|
f:497m
|
|
|
NotProcessed |
Lyplal1tm1a(KOMP)Wtsi
|
WTSI
|
Clinical Chemistry / Albumin
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.0344
|
Successful |
Lyplal1tm1b(KOMP)Wtsi
|
UC Davis
|
Clinical Chemistry / Albumin
|
HOM
|
7f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.538
|
Successful |
Lyplal1tm1b(KOMP)Wtsi
|
MRC Harwell
|
Clinical Chemistry / Albumin
|
HOM
|
8f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.900
|
Successful |
Lyplal1tm1b(KOMP)Wtsi
|
UC Davis
|
Body Composition (DEXA lean/fat) / Fat mass
|
HOM
|
10f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.492
|
Successful |
Lyplal1tm1a(KOMP)Wtsi
|
WTSI
|
Body Composition (DEXA lean/fat) / Fat mass
|
HOM
|
8f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.857
|
Successful |
Lyplal1tm1b(KOMP)Wtsi
|
MRC Harwell
|
Clinical Chemistry / Potassium
|
HOM
|
8f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.634
|
Successful |
Lyplal1tm1a(KOMP)Wtsi
|
WTSI
|
Clinical Chemistry / Potassium
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.696
|
Successful |
Lyplal1tm1a(KOMP)Wtsi
|
WTSI
|
Intraperitoneal glucose tolerance test (IPGTT) / Initial response to glucose challenge
|
HOM
|
8f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0205
|
Successful |
Lyplal1tm1b(KOMP)Wtsi
|
UC Davis
|
Intraperitoneal glucose tolerance test (IPGTT) / Initial response to glucose challenge
|
HOM
|
10f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0867
|
Successful |
Lyplal1tm1b(KOMP)Wtsi
|
MRC Harwell
|
Intraperitoneal glucose tolerance test (IPGTT) / Initial response to glucose challenge
|
HOM
|
8f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.677
|
Successful |
Lyplal1tm1a(KOMP)Wtsi
|
WTSI
|
Clinical Chemistry / Phosphorus
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.0134
|
Successful |
Lyplal1tm1b(KOMP)Wtsi
|
MRC Harwell
|
Clinical Chemistry / Phosphorus
|
HOM
|
8f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.670
|
Successful |
Lyplal1tm1b(KOMP)Wtsi
|
UC Davis
|
Clinical Chemistry / Phosphorus
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.680
|
Successful |
Lyplal1tm1b(KOMP)Wtsi
|
MRC Harwell
|
Clinical Chemistry / HDL-cholesterol
|
HOM
|
8f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.0243
|
Successful |
Lyplal1tm1a(KOMP)Wtsi
|
WTSI
|
Clinical Chemistry / HDL-cholesterol
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.0480
|
Successful |
Lyplal1tm1b(KOMP)Wtsi
|
UC Davis
|
Clinical Chemistry / HDL-cholesterol
|
HOM
|
5f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.202
|
Successful |
Lyplal1tm1a(KOMP)Wtsi
|
WTSI
|
Clinical Chemistry / Thyroxine
|
HOM
|
1f:3m
|
|
|
NotProcessed |
Lyplal1tm1b(KOMP)Wtsi
|
MRC Harwell
|
Clinical Chemistry / Chloride
|
HOM
|
8f:7m
|
|
|
NotProcessed |
Lyplal1tm1a(KOMP)Wtsi
|
WTSI
|
Clinical Chemistry / Chloride
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.0331
|
Successful |
Lyplal1tm1b(KOMP)Wtsi
|
UC Davis
|
Insulin Blood Level / Insulin
|
HOM
|
7f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.339
|
Successful |
Lyplal1tm1a(KOMP)Wtsi
|
WTSI
|
Insulin Blood Level / Insulin
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.912
|
Successful |
Lyplal1tm1a(KOMP)Wtsi
|
WTSI
|
Intraperitoneal glucose tolerance test (IPGTT) / Blood glucose concentration
|
HOM
|
40f:35m
|
|
|
NotProcessed |
Lyplal1tm1b(KOMP)Wtsi
|
MRC Harwell
|
Intraperitoneal glucose tolerance test (IPGTT) / Blood glucose concentration
|
HOM
|
40f:35m
|
|
|
NotProcessed |
Lyplal1tm1b(KOMP)Wtsi
|
UC Davis
|
Intraperitoneal glucose tolerance test (IPGTT) / Blood glucose concentration
|
HOM
|
50f:40m
|
|
|
NotProcessed |
Lyplal1tm1a(KOMP)Wtsi
|
WTSI
|
Intraperitoneal glucose tolerance test (IPGTT) / Fasted blood glucose concentration
|
HOM
|
8f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.00827
|
Successful |
Lyplal1tm1b(KOMP)Wtsi
|
UC Davis
|
Intraperitoneal glucose tolerance test (IPGTT) / Fasted blood glucose concentration
|
HOM
|
10f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.325
|
Successful |
Lyplal1tm1b(KOMP)Wtsi
|
MRC Harwell
|
Intraperitoneal glucose tolerance test (IPGTT) / Fasted blood glucose concentration
|
HOM
|
8f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.331
|
Successful |
Lyplal1tm1b(KOMP)Wtsi
|
UC Davis
|
Clinical Chemistry / Total bilirubin
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.164
|
Successful |
Lyplal1tm1a(KOMP)Wtsi
|
WTSI
|
Clinical Chemistry / Total bilirubin
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.166
|
Successful |
Lyplal1tm1b(KOMP)Wtsi
|
MRC Harwell
|
Clinical Chemistry / Total bilirubin
|
HOM
|
8f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.629
|
Successful |
Lyplal1tm1b(KOMP)Wtsi
|
UC Davis
|
Clinical Chemistry / Aspartate aminotransferase
|
HOM
|
7f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.0713
|
Successful |
Lyplal1tm1b(KOMP)Wtsi
|
MRC Harwell
|
Clinical Chemistry / Aspartate aminotransferase
|
HOM
|
8f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.837
|
Successful |
Lyplal1tm1a(KOMP)Wtsi
|
WTSI
|
Clinical Chemistry / Aspartate aminotransferase
|
HOM
|
7f:6m
|
Linear Mixed Model framework, LME, including Weight
|
0.959
|
Successful |
Lyplal1tm1b(KOMP)Wtsi
|
UC Davis
|
Indirect Calorimetry / Respiratory Exchange Ratio
|
HOM
|
f:1m
|
|
|
NotProcessed |
Lyplal1tm1b(KOMP)Wtsi
|
MRC Harwell
|
Indirect Calorimetry / Respiratory Exchange Ratio
|
HOM
|
f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.0561
|
Successful |
Lyplal1tm1a(KOMP)Wtsi
|
WTSI
|
Indirect Calorimetry / Respiratory Exchange Ratio
|
HOM
|
f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.468
|
Successful |
Lyplal1tm1a(KOMP)Wtsi
|
WTSI
|
Clinical Chemistry / LDL-cholesterol
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.554
|
Successful |
Lyplal1tm1b(KOMP)Wtsi
|
MRC Harwell
|
Indirect Calorimetry / Carbon dioxide production
|
HOM
|
f:497m
|
|
|
NotProcessed |
Lyplal1tm1b(KOMP)Wtsi
|
UC Davis
|
Indirect Calorimetry / Carbon dioxide production
|
HOM
|
f:81m
|
|
|
NotProcessed |
Lyplal1tm1a(KOMP)Wtsi
|
WTSI
|
Indirect Calorimetry / Carbon dioxide production
|
HOM
|
f:158m
|
|
|
NotProcessed |
Lyplal1tm1a(KOMP)Wtsi
|
WTSI
|
Clinical Chemistry / Triglycerides
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.188
|
Successful |
Lyplal1tm1b(KOMP)Wtsi
|
MRC Harwell
|
Clinical Chemistry / Triglycerides
|
HOM
|
8f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.537
|
Successful |
Lyplal1tm1a(KOMP)Wtsi
|
WTSI
|
Clinical Chemistry / Urea (Blood Urea Nitrogen - BUN)
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.00210
|
Successful |
Lyplal1tm1b(KOMP)Wtsi
|
UC Davis
|
Clinical Chemistry / Urea (Blood Urea Nitrogen - BUN)
|
HOM
|
7f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.0555
|
Successful |
Lyplal1tm1b(KOMP)Wtsi
|
MRC Harwell
|
Clinical Chemistry / Urea (Blood Urea Nitrogen - BUN)
|
HOM
|
8f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.185
|
Successful |