Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Combined SHIRPA and Dysmorphology / Tail - thickness
|
HET
|
8f:8m
|
|
|
NotProcessed |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Forepaw footpad size
|
HET
|
7f:7m
|
|
|
NotProcessed |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Combined SHIRPA and Dysmorphology / Coat - hair distribution - back
|
HET
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Eye Morphology / Bulging eye
|
HET
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Eye Morphology / Bulging eye
|
HET
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / External genitalia morphology
|
HET
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Open Field / Whole arena average speed series
|
HET
|
32f:32m
|
|
|
NotProcessed |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Eye Morphology / Iris/Pupil
|
HET
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Eye Morphology / Iris/Pupil
|
HET
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Adult LacZ / Cartilage tissue
|
HET
|
1f:1m
|
|
|
NotProcessed |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Snout morphology
|
HET
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Adult LacZ / Striatum
|
HET
|
1f:1m
|
|
|
NotProcessed |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Hematology / Mean cell hemoglobin concentration
|
HET
|
7f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
6.99×10-11
|
Successful |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Hematology / Mean cell hemoglobin concentration
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0362
|
Successful |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
X-ray / Kyphosis
|
HET
|
7f:7m
|
Fisher Exact Test framework
|
0.137
|
Successful |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
FACS / B2 Immature + MZB
|
HET
|
5f:4m
|
|
|
NotProcessed |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
FACS / Monocytes
|
HET
|
5f:4m
|
|
|
NotProcessed |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP2
|
HET
|
8f:8m
|
|
|
NotProcessed |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Indirect Calorimetry / Body weight before experiment
|
HET
|
f:7m
|
|
|
NotProcessed |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Indirect Calorimetry / Body weight before experiment
|
HET
|
f:7m
|
|
|
NotProcessed |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
X-ray / Lumbar processes
|
HET
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Incisors morphology
|
HET
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Heart Weight / Heart weight normalised against body weight
|
HET
|
7f:7m
|
|
|
NotProcessed |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Indirect Calorimetry / Total food intake
|
HET
|
f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0472
|
Successful |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
X-ray / Fibula
|
HET
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
X-ray / Fibula
|
HET
|
5f:5m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Auditory Brain Stem Response / 6kHz-evoked ABR Threshold
|
HET
|
2f:2m
|
|
|
NotProcessed |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Auditory Brain Stem Response / 6kHz-evoked ABR Threshold
|
HET
|
2f:2m
|
Reference Range Plus Test framework; quantile = 0.95 (Tails probability = 0.025)
|
0.0308
|
Successful |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
X-ray / Shape of vertebrae
|
HET
|
5f:5m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
X-ray / Shape of vertebrae
|
HET
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Trunk curl
|
HET
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Body Composition (DEXA lean/fat) / Body length
|
HET
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.877
|
Successful |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Cortical Bone MicroCT / Cortical Bone Mineral Density
|
HET
|
2f:m
|
|
|
NotProcessed |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Adult LacZ / Peyers Patch
|
HET
|
1f:1m
|
|
|
NotProcessed |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Adult LacZ / Small Intestine
|
HET
|
1f:1m
|
|
|
NotProcessed |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
FACS / T/NKT/B1
|
HET
|
5f:4m
|
|
|
NotProcessed |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Eye Morphology / Lens Opacity
|
HET
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Eye Morphology / Lens Opacity
|
HET
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Combined SHIRPA and Dysmorphology / Skin texture - back paws
|
HET
|
8f:8m
|
|
|
NotProcessed |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Limb skin appearance
|
HET
|
7f:7m
|
|
|
NotProcessed |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Antigen Specific Immunoglobulin Assay / Comment
|
HET
|
f:m
|
|
|
NotProcessed |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Clinical Chemistry / LDL-cholesterol
|
HET
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.634
|
Successful |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Combined SHIRPA and Dysmorphology / Forelimbs - shape
|
HET
|
8f:8m
|
|
|
NotProcessed |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Vertebral Microradiography / Vertebral Height
|
HET
|
2f:m
|
|
|
NotProcessed |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Open Field / Periphery distance travelled
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.416
|
Successful |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Adult LacZ / Lymph Node
|
HET
|
1f:1m
|
|
|
NotProcessed |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Hindlimb size
|
HET
|
7f:7m
|
|
|
NotProcessed |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Buffy coat peripheral blood leukocyte immunophenotyping / CD8+CD44+CD62L- percentage
|
HET
|
7f:7m
|
|
|
NotProcessed |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Forepaw morphology
|
HET
|
7f:7m
|
|
|
NotProcessed |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
X-ray / Zygomatic bone
|
HET
|
5f:5m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
X-ray / Zygomatic bone
|
HET
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
FACS / Spleen weight
|
HET
|
5f:4m
|
|
|
NotProcessed |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Head skin colour
|
HET
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Head coat/hair length
|
HET
|
7f:7m
|
|
|
NotProcessed |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Clinical Chemistry / Calcium
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.597
|
Successful |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Clinical Chemistry / Calcium
|
HET
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.946
|
Successful |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Echo / HR
|
HET
|
8f:m
|
Linear Mixed Model framework, LME, not including Weight
|
0.620
|
Successful |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Ventral coat/hair colour pattern
|
HET
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Limb coat/hair length
|
HET
|
7f:7m
|
|
|
NotProcessed |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Open Field / Percentage center movement time
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.489
|
Successful |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
X-ray / Shape of ribs
|
HET
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
X-ray / Shape of ribs
|
HET
|
5f:5m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Combined SHIRPA and Dysmorphology / Tail elevation
|
HET
|
8f:8m
|
|
|
NotProcessed |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Open Field / Periphery permanence time series
|
HET
|
32f:32m
|
|
|
NotProcessed |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Combined SHIRPA and Dysmorphology / Skin color - ear
|
HET
|
8f:8m
|
|
|
NotProcessed |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Electrocardiogram (ECG) / Number of signals
|
HET
|
8f:8m
|
|
|
NotProcessed |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Combined SHIRPA and Dysmorphology / Hindlimb nail - number
|
HET
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Grip Strength / Forelimb and hindlimb grip strength normalised against body weight
|
HET
|
8f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.141
|
Successful |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Grip Strength / Forelimb and hindlimb grip strength normalised against body weight
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.921
|
Successful |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Grip Strength / Body weight
|
HET
|
8f:8m
|
|
|
NotProcessed |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Grip Strength / Body weight
|
HET
|
8f:7m
|
|
|
NotProcessed |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Intraperitoneal glucose tolerance test (IPGTT) / Area under glucose response curve
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0621
|
Successful |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Intraperitoneal glucose tolerance test (IPGTT) / Area under glucose response curve
|
HET
|
7f:6m
|
Linear Mixed Model framework, LME, not including Weight
|
0.851
|
Successful |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Tail length
|
HET
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI3
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.288
|
Successful |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Clinical Chemistry / Potassium
|
HET
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.302
|
Successful |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Clinical Chemistry / Potassium
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.413
|
Successful |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Auditory Brain Stem Response / 30kHz-evoked ABR Threshold
|
HET
|
2f:2m
|
|
|
NotProcessed |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Auditory Brain Stem Response / 30kHz-evoked ABR Threshold
|
HET
|
2f:2m
|
Reference Range Plus Test framework; quantile = 0.95 (Tails probability = 0.025)
|
0.0359
|
Successful |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Clinical Chemistry / Phosphorus
|
HET
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.0441
|
Successful |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Clinical Chemistry / Phosphorus
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.945
|
Successful |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Combined SHIRPA and Dysmorphology / Hindpaw - shape
|
HET
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Viability Primary Screen / Viability Outcome
|
HOM
|
f:m
|
Supplied as data
|
0.00
|
Successful |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Viability Primary Screen / Viability Outcome
|
HOM
|
f:m
|
Supplied as data
|
0.00
|
Successful |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Combined SHIRPA and Dysmorphology / Genitalia - morphology
|
HET
|
8f:8m
|
|
|
NotProcessed |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Hematology / Large Unstained Cell (LUC) count
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0846
|
Successful |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Salmonella Challenge / Spleen Dilution Reading
|
HET
|
f:3m
|
|
|
NotProcessed |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Head bobbing/circling
|
HET
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Hematology / Lymphocyte cell count
|
HET
|
8f:8m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.638
|
Successful |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Combined SHIRPA and Dysmorphology / Head morphology
|
HET
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Forepaw nail colour
|
HET
|
7f:7m
|
|
|
NotProcessed |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Electrocardiogram (ECG) / ST
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.429
|
Successful |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Indirect Calorimetry / Respiratory Exchange Ratio
|
HET
|
f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.0551
|
Successful |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Indirect Calorimetry / Respiratory Exchange Ratio
|
HET
|
f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.0880
|
Successful |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Digit coat/hair colour pattern
|
HET
|
7f:7m
|
|
|
NotProcessed |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Eye Morphology / Corneal vascularization
|
HET
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Eye Morphology / Corneal vascularization
|
HET
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
FACS / CD8 Resting
|
HET
|
5f:4m
|
|
|
NotProcessed |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Eye Morphology / Retinal Blood Vessels Pattern
|
HET
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Eye Morphology / Retinal Blood Vessels Pattern
|
HET
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Clinical Chemistry / Triglycerides
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.0249
|
Successful |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Clinical Chemistry / Triglycerides
|
HET
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.633
|
Successful |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Head size
|
HET
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
FACS / B2 Total
|
HET
|
5f:4m
|
|
|
NotProcessed |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Hematology / Platelet count
|
HET
|
7f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.197
|
Successful |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Hematology / Platelet count
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.602
|
Successful |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / External genitalia
|
HET
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP1
|
HET
|
8f:8m
|
|
|
NotProcessed |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
FACS / Macrophages
|
HET
|
5f:4m
|
|
|
NotProcessed |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
FACS / CD8 Naive
|
HET
|
5f:4m
|
|
|
NotProcessed |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Hindlimb morphology
|
HET
|
7f:7m
|
|
|
NotProcessed |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Indirect Calorimetry / Cumulative food intake
|
HET
|
f:154m
|
|
|
NotProcessed |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Adult LacZ / Thymus
|
HET
|
1f:1m
|
|
|
NotProcessed |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Transfer arousal
|
HET
|
7f:7m
|
Fisher Exact Test framework
|
0.186
|
Successful |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Adult LacZ / Skeletal Muscle
|
HET
|
1f:1m
|
|
|
NotProcessed |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Open Field / Periphery distance travelled series
|
HET
|
32f:32m
|
|
|
NotProcessed |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Eye Morphology / Pupil Position
|
HET
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Eye Morphology / Pupil Position
|
HET
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Combined SHIRPA and Dysmorphology / Hindlimbs - position
|
HET
|
8f:8m
|
|
|
NotProcessed |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Limb skin colour
|
HET
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Adult LacZ / Peripheral Nervous System
|
HET
|
1f:1m
|
|
|
NotProcessed |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Open Field / Latency to center entry
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.842
|
Successful |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
X-ray / Scoliosis
|
HET
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Incisor colour
|
HET
|
7f:7m
|
|
|
NotProcessed |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Combined SHIRPA and Dysmorphology / Forelimbs - size
|
HET
|
8f:8m
|
|
|
NotProcessed |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Adult LacZ / Mammary gland
|
HET
|
1f:1m
|
|
|
NotProcessed |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
X-ray / Fusion of vertebrae
|
HET
|
7f:7m
|
Fisher Exact Test framework
|
0.606
|
Successful |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
X-ray / Fusion of vertebrae
|
HET
|
5f:5m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Combined SHIRPA and Dysmorphology / Tail - morphology
|
HET
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
X-ray / Tibia
|
HET
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
X-ray / Tibia
|
HET
|
5f:5m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Combined SHIRPA and Dysmorphology / Coat - color pattern - abdomen
|
HET
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
FACS / Tregs
|
HET
|
5f:4m
|
|
|
NotProcessed |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Head skin appearance
|
HET
|
7f:7m
|
|
|
NotProcessed |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Grip Strength / Forelimb and hindlimb grip strength measurement mean
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.765
|
Successful |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Grip Strength / Forelimb and hindlimb grip strength measurement mean
|
HET
|
8f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.853
|
Successful |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Paw footpad skin appearance
|
HET
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Salmonella Challenge / Caecal Contents Dilution Reading
|
HET
|
f:3m
|
|
|
NotProcessed |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Digit coat/hair appearance
|
HET
|
7f:7m
|
|
|
NotProcessed |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Adult LacZ / Adrenal gland
|
HET
|
1f:1m
|
|
|
NotProcessed |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Electrocardiogram (ECG) / QTc
|
HET
|
8f:8m
|
|
|
NotProcessed |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Eye Morphology / Lens
|
HET
|
8f:8m
|
Fisher Exact Test framework
|
0.0672
|
Successful |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Eye Morphology / Lens
|
HET
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Grip Strength / Forelimb grip strength normalised against body weight
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0752
|
Successful |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Grip Strength / Forelimb grip strength normalised against body weight
|
HET
|
8f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.289
|
Successful |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Combined SHIRPA and Dysmorphology / Head size
|
HET
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Tail morphology
|
HET
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Open Field / Center average speed
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.745
|
Successful |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Clinical Chemistry / Sodium
|
HET
|
8f:8m
|
|
|
NotProcessed |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Clinical Chemistry / Sodium
|
HET
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.447
|
Successful |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Combined SHIRPA and Dysmorphology / Forepaw - shape
|
HET
|
8f:8m
|
|
|
NotProcessed |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Buffy coat peripheral blood leukocyte immunophenotyping / T cell CD3+ percentage
|
HET
|
7f:7m
|
|
|
NotProcessed |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Femoral Microradiography / Femur Length
|
HET
|
2f:m
|
|
|
NotProcessed |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
X-ray / Alive
|
HET
|
7f:7m
|
|
|
NotProcessed |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
X-ray / Alive
|
HET
|
5f:5m
|
|
|
NotProcessed |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Ventral coat/hair colour
|
HET
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Body Composition (DEXA lean/fat) / Bone Mineral Content (excluding skull)
|
HET
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.456
|
Successful |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Body Composition (DEXA lean/fat) / Bone Mineral Content (excluding skull)
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.999
|
Successful |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Corneal touch reflex
|
HET
|
7f:7m
|
|
|
NotProcessed |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
FACS / Number of live cells acquired Panel 1
|
HET
|
5f:4m
|
|
|
NotProcessed |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Hematology / Neutrophil differential count
|
HET
|
8f:8m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.0378
|
Successful |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Contact righting reflex
|
HET
|
7f:7m
|
|
|
NotProcessed |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Combined SHIRPA and Dysmorphology / Skin color - snout
|
HET
|
8f:8m
|
|
|
NotProcessed |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Forepaw nail morphology
|
HET
|
7f:7m
|
|
|
NotProcessed |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Adult LacZ / Trachea
|
HET
|
1f:1m
|
|
|
NotProcessed |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Buffy coat peripheral blood leukocyte immunophenotyping / Comment
|
HET
|
f:m
|
|
|
NotProcessed |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Clinical Chemistry / HDL-cholesterol
|
HET
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.0106
|
Successful |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Clinical Chemistry / HDL-cholesterol
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.0817
|
Successful |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Eye Morphology / Persistence of hyaloid vascular system
|
HET
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Eye Morphology / Persistence of hyaloid vascular system
|
HET
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI2
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.130
|
Successful |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Adult LacZ / Cerebral Cortex
|
HET
|
1f:1m
|
|
|
NotProcessed |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Eye Morphology / Eye
|
HET
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
X-ray / Processes on vertebrae
|
HET
|
5f:5m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Vertebra Compression / Vertebra Yield Load
|
HET
|
2f:m
|
|
|
NotProcessed |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
X-ray / Maxilla/Pre-maxilla
|
HET
|
5f:5m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
X-ray / Maxilla/Pre-maxilla
|
HET
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Hematology / Lymphocyte differential count
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0582
|
Successful |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Viability E12.5 Secondary Screen / Outcome
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Combined SHIRPA and Dysmorphology / Mouth morphology
|
HET
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Adult LacZ / Testis
|
HET
|
1f:1m
|
|
|
NotProcessed |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Gait (inc. ataxia)
|
HET
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Tail coat/hair appearance
|
HET
|
7f:7m
|
|
|
NotProcessed |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Adult LacZ / Kidney
|
HET
|
1f:1m
|
|
|
NotProcessed |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
X-ray / Caudal processes
|
HET
|
7f:7m
|
|
|
NotProcessed |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Ventral skin appearance
|
HET
|
7f:7m
|
|
|
NotProcessed |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Hindlimb
|
HET
|
7f:7m
|
|
|
NotProcessed |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Combined SHIRPA and Dysmorphology / Head bobbing
|
HET
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Head morphology
|
HET
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Adult LacZ / Pituitary gland
|
HET
|
1f:1m
|
|
|
NotProcessed |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Dorsal coat/hair colour
|
HET
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
X-ray / Number of ribs right
|
HET
|
5f:5m
|
|
|
NotProcessed |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
X-ray / Number of ribs right
|
HET
|
7f:7m
|
|
|
NotProcessed |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Open Field / Periphery resting time series
|
HET
|
32f:32m
|
|
|
NotProcessed |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Electrocardiogram (ECG) / rMSSD
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.755
|
Successful |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Combined SHIRPA and Dysmorphology / Skin texture - ear
|
HET
|
8f:8m
|
|
|
NotProcessed |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Eye Morphology / Retina
|
HET
|
7f:7m
|
|
|
NotProcessed |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Eye Morphology / Retina
|
HET
|
8f:8m
|
|
|
NotProcessed |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Body Composition (DEXA lean/fat) / Body weight
|
HET
|
8f:8m
|
|
|
NotProcessed |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Body Composition (DEXA lean/fat) / Body weight
|
HET
|
7f:7m
|
|
|
NotProcessed |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Open Field / Center average speed series
|
HET
|
32f:32m
|
|
|
NotProcessed |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Clinical Chemistry / Alpha-amylase
|
HET
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.00690
|
Successful |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Clinical Chemistry / Alpha-amylase
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.540
|
Successful |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Electrocardiogram (ECG) / PR
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.0162
|
Successful |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
FACS / CD8 Effector
|
HET
|
5f:4m
|
|
|
NotProcessed |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Clinical Chemistry / Iron
|
HET
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.280
|
Successful |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Clinical Chemistry / Iron
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.710
|
Successful |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Clinical Chemistry / Magnesium
|
HET
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.00145
|
Successful |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Convulsions
|
HET
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Combined SHIRPA and Dysmorphology / Genitalia - size
|
HET
|
8f:8m
|
|
|
NotProcessed |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Open Field / Periphery permanence time
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.358
|
Successful |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Combined SHIRPA and Dysmorphology / Forelimb nail - length
|
HET
|
8f:8m
|
|
|
NotProcessed |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
FACS / Total cell count in spleen
|
HET
|
5f:4m
|
|
|
NotProcessed |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Echo / LVAWd
|
HET
|
8f:m
|
Linear Mixed Model framework, LME, including Weight
|
0.116
|
Successful |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Forepaw digit size
|
HET
|
7f:7m
|
|
|
NotProcessed |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Salmonella Challenge / Pre-Day 14 Death
|
HET
|
f:3m
|
|
|
NotProcessed |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Combined SHIRPA and Dysmorphology / Aggression
|
HET
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Hindpaw digit fusion
|
HET
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Open Field / Number of center entries
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.677
|
Successful |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Tail
|
HET
|
7f:7m
|
|
|
NotProcessed |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Adult LacZ / Olfactory Lobe
|
HET
|
1f:1m
|
|
|
NotProcessed |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Grip Strength / Forelimb grip strength measurement mean
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.0287
|
Successful |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Grip Strength / Forelimb grip strength measurement mean
|
HET
|
8f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.523
|
Successful |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Combined SHIRPA and Dysmorphology / Startle response
|
HET
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Combined SHIRPA and Dysmorphology / Hindlimbs - shape
|
HET
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
FACS / Tregs Effector
|
HET
|
5f:4m
|
|
|
NotProcessed |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Ventral coat/hair appearance
|
HET
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Three-point Bend / Energy Dissipated Prior to Fracture
|
HET
|
2f:m
|
|
|
NotProcessed |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - BN
|
HET
|
8f:8m
|
|
|
NotProcessed |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Echo / LVPWs
|
HET
|
8f:m
|
Linear Mixed Model framework, LME, not including Weight
|
0.971
|
Successful |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Limb coat/hair appearance
|
HET
|
7f:7m
|
|
|
NotProcessed |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
X-ray / Femur
|
HET
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
X-ray / Femur
|
HET
|
5f:5m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Pinna
|
HET
|
7f:7m
|
|
|
NotProcessed |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Eye Morphology / Cornea
|
HET
|
7f:7m
|
Fisher Exact Test framework
|
0.469
|
Successful |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Eye Morphology / Cornea
|
HET
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Clinical Chemistry / Free fatty acids
|
HET
|
7f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.660
|
Successful |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Auditory Brain Stem Response / 12kHz-evoked ABR Threshold
|
HET
|
2f:2m
|
|
|
NotProcessed |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Auditory Brain Stem Response / 12kHz-evoked ABR Threshold
|
HET
|
2f:2m
|
Reference Range Plus Test framework; quantile = 0.95 (Tails probability = 0.025)
|
0.0308
|
Successful |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
FACS / gd + B1
|
HET
|
5f:4m
|
|
|
NotProcessed |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Hematology / Basophil cell count
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.420
|
Successful |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Body Composition (DEXA lean/fat) / Bone Mineral Density (excluding skull)
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.741
|
Successful |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Body Composition (DEXA lean/fat) / Bone Mineral Density (excluding skull)
|
HET
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.918
|
Successful |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Pinna position
|
HET
|
7f:7m
|
|
|
NotProcessed |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Echo / Ejection Fraction
|
HET
|
8f:m
|
Linear Mixed Model framework, LME, not including Weight
|
0.378
|
Successful |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Hematology / Red blood cell count
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0411
|
Successful |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Hematology / Red blood cell count
|
HET
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.654
|
Successful |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Paw coat/hair colour
|
HET
|
7f:7m
|
|
|
NotProcessed |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Clinical Chemistry / LIH (Hemolysis Severity - available on AU analysers)
|
HET
|
8f:8m
|
|
|
NotProcessed |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Hindpaw digit count
|
HET
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Combined SHIRPA and Dysmorphology / Skin texture - tail
|
HET
|
8f:8m
|
|
|
NotProcessed |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Buffy coat peripheral blood leukocyte immunophenotyping / Mature B cell IgD+ percentage
|
HET
|
7f:7m
|
|
|
NotProcessed |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Eye Morphology / Iris Pigmentation
|
HET
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Eye Morphology / Iris Pigmentation
|
HET
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Combined SHIRPA and Dysmorphology / Vibrissae - appearance
|
HET
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Paw footpad skin colour
|
HET
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Buffy coat peripheral blood leukocyte immunophenotyping / T cell CD4+ percentage
|
HET
|
7f:7m
|
|
|
NotProcessed |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
FACS / B2 Mature
|
HET
|
5f:4m
|
|
|
NotProcessed |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Salmonella Challenge / Liver Weight
|
HET
|
f:3m
|
|
|
NotProcessed |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Organ Weight / Right kidney
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.267
|
Successful |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Startle response
|
HET
|
7f:7m
|
Fisher Exact Test framework
|
0.193
|
Successful |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Hematology / Neutrophil cell count
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.266
|
Successful |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
X-ray / Thoracic processes
|
HET
|
7f:7m
|
Fisher Exact Test framework
|
0.386
|
Successful |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
X-ray / Humerus
|
HET
|
5f:5m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
X-ray / Humerus
|
HET
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Combined SHIRPA and Dysmorphology / Limb grasp
|
HET
|
8f:8m
|
Fisher Exact Test framework
|
0.132
|
Successful |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Viability E14.5-E15.5 Secondary Screen / Outcome
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Viability E14.5-E15.5 Secondary Screen / Outcome
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Adult LacZ / Cerebellum
|
HET
|
1f:1m
|
|
|
NotProcessed |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Clinical Chemistry / Urea (Blood Urea Nitrogen - BUN)
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.214
|
Successful |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Clinical Chemistry / Urea (Blood Urea Nitrogen - BUN)
|
HET
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.269
|
Successful |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Combined SHIRPA and Dysmorphology / Coat - color pattern - head
|
HET
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Electrocardiogram (ECG) / Mean R amplitude
|
HET
|
8f:8m
|
|
|
NotProcessed |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Combined SHIRPA and Dysmorphology / Genitalia - presence
|
HET
|
8f:8m
|
|
|
NotProcessed |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Open Field / Periphery resting time
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.615
|
Successful |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
X-ray / Number of lumbar vertebrae
|
HET
|
7f:7m
|
|
|
NotProcessed |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
X-ray / Lordosis
|
HET
|
7f:7m
|
|
|
NotProcessed |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Ventral skin colour
|
HET
|
7f:7m
|
|
|
NotProcessed |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
X-ray / Ulna
|
HET
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
X-ray / Ulna
|
HET
|
5f:5m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
X-ray / Sacral processes
|
HET
|
7f:7m
|
|
|
NotProcessed |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Tail coat/hair length
|
HET
|
7f:7m
|
|
|
NotProcessed |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Organ Weight / Spleen weight
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.117
|
Successful |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Forepaw digit count
|
HET
|
7f:7m
|
|
|
NotProcessed |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Combined SHIRPA and Dysmorphology / Hindlimb digit - number
|
HET
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Combined SHIRPA and Dysmorphology / Tail - length
|
HET
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Indirect Calorimetry / Body weight after experiment
|
HET
|
f:7m
|
|
|
NotProcessed |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Indirect Calorimetry / Body weight after experiment
|
HET
|
f:7m
|
|
|
NotProcessed |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Digit coat/hair presence
|
HET
|
7f:7m
|
|
|
NotProcessed |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / External genitalia size
|
HET
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
X-ray / Number of caudal vertebrae
|
HET
|
7f:7m
|
|
|
NotProcessed |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Salmonella Challenge / Liver Counts in 20 micro litres
|
HET
|
f:3m
|
|
|
NotProcessed |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Combined SHIRPA and Dysmorphology / Unexpected behaviors
|
HET
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - Global
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.491
|
Successful |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
X-ray / Number of ribs left
|
HET
|
7f:7m
|
|
|
NotProcessed |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
X-ray / Number of ribs left
|
HET
|
5f:5m
|
|
|
NotProcessed |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Open Field / Distance travelled
|
HET
|
32f:32m
|
|
|
NotProcessed |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Hindpaw nail colour
|
HET
|
7f:7m
|
|
|
NotProcessed |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Combined SHIRPA and Dysmorphology / Hindlimbs - size
|
HET
|
8f:8m
|
|
|
NotProcessed |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Ventral coat/hair length
|
HET
|
7f:7m
|
|
|
NotProcessed |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Combined SHIRPA and Dysmorphology / Skin texture - front paws
|
HET
|
8f:8m
|
|
|
NotProcessed |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Body Composition (DEXA lean/fat) / Bone Area
|
HET
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.190
|
Successful |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Body Composition (DEXA lean/fat) / Bone Area
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.548
|
Successful |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Adult LacZ / Vascular System
|
HET
|
1f:1m
|
|
|
NotProcessed |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Electrocardiogram (ECG) / QT
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.643
|
Successful |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Echo / LVIDs
|
HET
|
8f:m
|
Linear Mixed Model framework, LME, including Weight
|
0.521
|
Successful |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Echo / Cardiac Output
|
HET
|
8f:m
|
Linear Mixed Model framework, LME, including Weight
|
0.687
|
Successful |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
FACS / pDCs
|
HET
|
5f:4m
|
|
|
NotProcessed |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Eye Morphology / Retinal Pigmentation
|
HET
|
7f:7m
|
|
|
NotProcessed |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Eye Morphology / Retinal Pigmentation
|
HET
|
8f:8m
|
|
|
NotProcessed |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
FACS / CD4 T cells total
|
HET
|
5f:4m
|
|
|
NotProcessed |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Adult LacZ / Liver
|
HET
|
1f:1m
|
|
|
NotProcessed |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Adult LacZ / Gall Bladder
|
HET
|
1f:1m
|
|
|
NotProcessed |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Adult LacZ / Stomach
|
HET
|
1f:1m
|
|
|
NotProcessed |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Combined SHIRPA and Dysmorphology / Forelimbs - position
|
HET
|
8f:8m
|
|
|
NotProcessed |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Hindpaw digit morphology
|
HET
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Salmonella Challenge / Comment
|
HET
|
f:m
|
|
|
NotProcessed |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Tail skin colour
|
HET
|
7f:7m
|
|
|
NotProcessed |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Dorsal coat/hair presence
|
HET
|
7f:7m
|
Fisher Exact Test framework
|
0.0764
|
Successful |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP3_S
|
HET
|
8f:8m
|
|
|
NotProcessed |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Paw coat/hair presence
|
HET
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Pinna morphology
|
HET
|
7f:7m
|
|
|
NotProcessed |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Hindpaw digit size
|
HET
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Combined SHIRPA and Dysmorphology / Skin color - front paws
|
HET
|
8f:8m
|
|
|
NotProcessed |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Hematology / Basophil differential count
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.990
|
Successful |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Combined SHIRPA and Dysmorphology / Coat - hair texture / appearance - abdomen
|
HET
|
8f:8m
|
|
|
NotProcessed |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP2_S
|
HET
|
8f:8m
|
|
|
NotProcessed |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Adult LacZ / Hippocampus
|
HET
|
1f:1m
|
|
|
NotProcessed |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Clinical Chemistry / Glucose
|
HET
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.161
|
Successful |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Clinical Chemistry / Glucose
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.334
|
Successful |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
FACS / iNKT
|
HET
|
5f:4m
|
|
|
NotProcessed |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
X-ray / Skull shape
|
HET
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
X-ray / Skull shape
|
HET
|
5f:5m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Echo / Fractional Shortening
|
HET
|
8f:m
|
Linear Mixed Model framework, LME, not including Weight
|
0.463
|
Successful |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Combined SHIRPA and Dysmorphology / Forelimb nail - number
|
HET
|
8f:8m
|
|
|
NotProcessed |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Indirect Calorimetry / Oxygen consumption
|
HET
|
f:154m
|
|
|
NotProcessed |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Indirect Calorimetry / Oxygen consumption
|
HET
|
f:553m
|
|
|
NotProcessed |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Adult LacZ / Spinal cord
|
HET
|
1f:1m
|
|
|
NotProcessed |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Electrocardiogram (ECG) / QRS
|
HET
|
8f:8m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.598
|
Successful |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Forelimb
|
HET
|
7f:7m
|
|
|
NotProcessed |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Combined SHIRPA and Dysmorphology / Forelimb digit - number
|
HET
|
8f:8m
|
|
|
NotProcessed |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
FACS / cDC CD8a type
|
HET
|
5f:4m
|
|
|
NotProcessed |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Digit coat/hair colour
|
HET
|
7f:7m
|
|
|
NotProcessed |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Combined SHIRPA and Dysmorphology / Tail - presence
|
HET
|
8f:8m
|
|
|
NotProcessed |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Clinical Chemistry / Chloride
|
HET
|
8f:8m
|
|
|
NotProcessed |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Clinical Chemistry / Chloride
|
HET
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.0818
|
Successful |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Insulin Blood Level / Insulin
|
HET
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.511
|
Successful |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI4
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.273
|
Successful |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Body Composition (DEXA lean/fat) / Lean mass
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.254
|
Successful |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Body Composition (DEXA lean/fat) / Lean mass
|
HET
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
4.83×10-05
|
Successful |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Eye Morphology / Pupil Light Response
|
HET
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Eye Morphology / Pupil Light Response
|
HET
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Eye Morphology / Corneal opacity
|
HET
|
7f:7m
|
Fisher Exact Test framework
|
0.190
|
Successful |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Eye Morphology / Corneal opacity
|
HET
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Buffy coat peripheral blood leukocyte immunophenotyping / Treg cell CD25+ percentage
|
HET
|
7f:7m
|
|
|
NotProcessed |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Adult LacZ / Prostate gland
|
HET
|
1f:1m
|
|
|
NotProcessed |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
X-ray / Number of pelvic vertebrae
|
HET
|
7f:7m
|
|
|
NotProcessed |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
X-ray / Shape of ribcage
|
HET
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Tremor
|
HET
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Organ Weight / Left kidney
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.534
|
Successful |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Hematology / White blood cell count
|
HET
|
7f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0430
|
Successful |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Hematology / White blood cell count
|
HET
|
8f:8m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.639
|
Successful |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Combined SHIRPA and Dysmorphology / Forelimb digit - size
|
HET
|
8f:8m
|
|
|
NotProcessed |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Clinical Chemistry / Alanine aminotransferase
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.547
|
Successful |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Clinical Chemistry / Alanine aminotransferase
|
HET
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.848
|
Successful |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Eye Morphology / Ophthalmoscope Observation
|
HET
|
1f:m
|
|
|
NotProcessed |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Eye Morphology / Ophthalmoscope Observation
|
HET
|
2f:1m
|
|
|
NotProcessed |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Echo / LVPWd
|
HET
|
8f:m
|
Linear Mixed Model framework, LME, including Weight
|
0.643
|
Successful |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Combined SHIRPA and Dysmorphology / Forelimb nail - shape
|
HET
|
8f:8m
|
|
|
NotProcessed |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Electrocardiogram (ECG) / RR
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.879
|
Successful |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Open Field / Center resting time series
|
HET
|
32f:32m
|
|
|
NotProcessed |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Combined SHIRPA and Dysmorphology / Skin texture - whole body
|
HET
|
8f:8m
|
|
|
NotProcessed |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Combined SHIRPA and Dysmorphology / Trunk curl
|
HET
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Clinical Chemistry / Creatinine
|
HET
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.000103
|
Successful |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Clinical Chemistry / Creatinine
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.593
|
Successful |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Dorsal coat/hair appearance
|
HET
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
X-ray / Number of thoracic vertebrae
|
HET
|
7f:7m
|
|
|
NotProcessed |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Limb coat/hair colour
|
HET
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Trabecular Bone MicroCT / Trabecular Thickness (mm)
|
HET
|
2f:m
|
|
|
NotProcessed |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
X-ray / Radius
|
HET
|
5f:5m
|
|
|
NotProcessed |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
X-ray / Radius
|
HET
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Tail coat/hair colour
|
HET
|
7f:7m
|
|
|
NotProcessed |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Hematology / Mean platelet volume
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0964
|
Successful |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Hematology / Mean platelet volume
|
HET
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.410
|
Successful |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Hematology / Eosinophil differential count
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.489
|
Successful |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Open Field / Percentage center time
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.616
|
Successful |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Echo / LVAWs
|
HET
|
8f:m
|
Linear Mixed Model framework, LME, including Weight
|
0.360
|
Successful |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
X-ray / Brachydactyly
|
HET
|
5f:5m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
X-ray / Brachydactyly
|
HET
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
FACS / Number of live cells acquired Panel 2
|
HET
|
5f:4m
|
|
|
NotProcessed |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Combined SHIRPA and Dysmorphology / Vibrissae - presence
|
HET
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Tail skin appearance
|
HET
|
7f:7m
|
|
|
NotProcessed |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Combined SHIRPA and Dysmorphology / Lower teeth appearance
|
HET
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Hindpaw nail morphology
|
HET
|
7f:7m
|
|
|
NotProcessed |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
X-ray / Scapulae
|
HET
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
X-ray / Scapulae
|
HET
|
5f:5m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Buffy coat peripheral blood leukocyte immunophenotyping / Monocyte percentage
|
HET
|
7f:7m
|
|
|
NotProcessed |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Head coat/hair presence
|
HET
|
7f:7m
|
Fisher Exact Test framework
|
0.523
|
Successful |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Forepaw digit fusion
|
HET
|
7f:7m
|
|
|
NotProcessed |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Adult LacZ / Parathyroid gland
|
HET
|
1f:1m
|
|
|
NotProcessed |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Eye Morphology / Retinal Structure
|
HET
|
7f:7m
|
|
|
NotProcessed |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Eye Morphology / Retinal Structure
|
HET
|
8f:8m
|
|
|
NotProcessed |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Adult LacZ / Skin
|
HET
|
1f:1m
|
|
|
NotProcessed |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
FACS / CD4 Resting/Naive
|
HET
|
5f:4m
|
|
|
NotProcessed |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Adult LacZ / Esophagus
|
HET
|
1f:1m
|
|
|
NotProcessed |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Eye Morphology / Retina (combined)
|
HET
|
7f:7m
|
Fisher Exact Test framework
|
0.489
|
Successful |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Eye Morphology / Retina (combined)
|
HET
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Heart Weight / Body weight
|
HET
|
7f:7m
|
|
|
NotProcessed |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Organ Weight / Body weight
|
HET
|
8f:8m
|
|
|
NotProcessed |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Adult LacZ / Pancreas
|
HET
|
1f:1m
|
|
|
NotProcessed |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Pinna size
|
HET
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
X-ray / Polysyndactylism
|
HET
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
FACS / cDC CD11b type
|
HET
|
5f:4m
|
|
|
NotProcessed |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Combined SHIRPA and Dysmorphology / Contact righting
|
HET
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Hematology / Hematocrit
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0343
|
Successful |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Hematology / Hematocrit
|
HET
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.752
|
Successful |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Antigen Specific Immunoglobulin Assay / TetC specific total IgG
|
HET
|
f:3m
|
|
|
NotProcessed |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Combined SHIRPA and Dysmorphology / Coat - hair texture / appearance - head
|
HET
|
8f:8m
|
|
|
NotProcessed |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Vibrissae shape
|
HET
|
7f:7m
|
|
|
NotProcessed |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Clinical Chemistry / Creatine kinase
|
HET
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.0684
|
Successful |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Clinical Chemistry / Creatine kinase
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.620
|
Successful |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Combined SHIRPA and Dysmorphology / Coat - color - abdomen
|
HET
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP1_S
|
HET
|
8f:8m
|
|
|
NotProcessed |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
FACS / Tregs Resting
|
HET
|
5f:4m
|
|
|
NotProcessed |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Adult LacZ / Hypothalamus
|
HET
|
1f:1m
|
|
|
NotProcessed |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Eye Morphology / Pupil Dilation
|
HET
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Eye Morphology / Pupil Dilation
|
HET
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Body Composition (DEXA lean/fat) / Fat mass
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.328
|
Successful |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Body Composition (DEXA lean/fat) / Fat mass
|
HET
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.354
|
Successful |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
FACS / NK Total
|
HET
|
5f:4m
|
|
|
NotProcessed |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Three-point Bend / Stiffness
|
HET
|
2f:m
|
|
|
NotProcessed |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Paw coat/hair appearance
|
HET
|
7f:7m
|
|
|
NotProcessed |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Salmonella Challenge / Liver Dilution Reading
|
HET
|
f:3m
|
|
|
NotProcessed |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Clinical Chemistry / Thyroxine
|
HET
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.00600
|
Successful |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Combined SHIRPA and Dysmorphology / Tremor
|
HET
|
8f:8m
|
Fisher Exact Test framework
|
0.167
|
Successful |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Echo / End-Diastolic Diameter
|
HET
|
8f:m
|
Linear Mixed Model framework, LME, including Weight
|
0.407
|
Successful |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Forelimb size
|
HET
|
7f:7m
|
|
|
NotProcessed |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Indirect Calorimetry / Total water intake
|
HET
|
f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.758
|
Successful |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Tail elevation
|
HET
|
7f:7m
|
|
|
NotProcessed |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Dorsal skin colour
|
HET
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Combined SHIRPA and Dysmorphology / Upper teeth appearance
|
HET
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Indirect Calorimetry / Carbon dioxide production
|
HET
|
f:154m
|
|
|
NotProcessed |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Indirect Calorimetry / Carbon dioxide production
|
HET
|
f:553m
|
|
|
NotProcessed |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Buffy coat peripheral blood leukocyte immunophenotyping / T cell CD8+ percentage
|
HET
|
7f:7m
|
|
|
NotProcessed |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Intraperitoneal glucose tolerance test (IPGTT) / Body Weight
|
HET
|
7f:7m
|
|
|
NotProcessed |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Intraperitoneal glucose tolerance test (IPGTT) / Body Weight
|
HET
|
8f:8m
|
|
|
NotProcessed |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Open Field / Center distance travelled
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.554
|
Successful |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Adult LacZ / Eye
|
HET
|
1f:1m
|
|
|
NotProcessed |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Auditory Brain Stem Response / 18kHz-evoked ABR Threshold
|
HET
|
2f:2m
|
|
|
NotProcessed |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Auditory Brain Stem Response / 18kHz-evoked ABR Threshold
|
HET
|
2f:2m
|
Reference Range Plus Test framework; quantile = 0.95 (Tails probability = 0.025)
|
0.0564
|
Successful |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Hindpaw morphology
|
HET
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Electrocardiogram (ECG) / Mean SR amplitude
|
HET
|
8f:8m
|
|
|
NotProcessed |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Adult LacZ / Thyroid gland
|
HET
|
1f:1m
|
|
|
NotProcessed |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
X-ray / Clavicle
|
HET
|
5f:5m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
X-ray / Clavicle
|
HET
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Body Weight / Body weight curve
|
HET
|
123f:142m
|
|
|
NotProcessed |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Body Weight / Body weight curve
|
HET
|
98f:121m
|
|
|
NotProcessed |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Open Field / Center permanence time series
|
HET
|
32f:32m
|
|
|
NotProcessed |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Auditory Brain Stem Response / Body weight
|
HET
|
2f:2m
|
|
|
NotProcessed |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Electrocardiogram (ECG) / PQ
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.0115
|
Successful |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Combined SHIRPA and Dysmorphology / Activity (body position)
|
HET
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Trabecular Bone MicroCT / Trabecular Spacing (mm)
|
HET
|
2f:m
|
|
|
NotProcessed |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Adult LacZ / Heart
|
HET
|
1f:1m
|
|
|
NotProcessed |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Buffy coat peripheral blood leukocyte immunophenotyping / NK cell percentage
|
HET
|
7f:7m
|
|
|
NotProcessed |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Combined SHIRPA and Dysmorphology / Hindlimb digit - size
|
HET
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Tail coat/hair colour pattern
|
HET
|
7f:7m
|
|
|
NotProcessed |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
X-ray / Digit integrity
|
HET
|
5f:5m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
X-ray / Digit integrity
|
HET
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Hindpaw nail length
|
HET
|
7f:7m
|
|
|
NotProcessed |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Eye Morphology / Slit Lamp observation
|
HET
|
1f:m
|
|
|
NotProcessed |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Combined SHIRPA and Dysmorphology / Skin texture - snout
|
HET
|
8f:8m
|
|
|
NotProcessed |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Clinical Chemistry / Total protein
|
HET
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.00599
|
Successful |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Clinical Chemistry / Total protein
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.319
|
Successful |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Echo / Respiration Rate
|
HET
|
5f:m
|
Linear Mixed Model framework, LME, not including Weight
|
0.503
|
Successful |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Body Composition (DEXA lean/fat) / Fat/Body weight
|
HET
|
7f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.196
|
Successful |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Body Composition (DEXA lean/fat) / Fat/Body weight
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.596
|
Successful |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Dorsal coat/hair colour pattern
|
HET
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
X-ray / Number of cervical vertebrae
|
HET
|
7f:7m
|
|
|
NotProcessed |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Eye Morphology / Eyelid closure
|
HET
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Eye Morphology / Eyelid closure
|
HET
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Head coat/hair colour
|
HET
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Three-point Bend / Fracture Load
|
HET
|
2f:m
|
|
|
NotProcessed |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Salmonella Challenge / Days post-infection
|
HET
|
f:3m
|
|
|
NotProcessed |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Buffy coat peripheral blood leukocyte immunophenotyping / Granulocyte Gr1+ percentage
|
HET
|
7f:7m
|
|
|
NotProcessed |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Adult LacZ / Oviduct
|
HET
|
1f:1m
|
|
|
NotProcessed |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Limb coat/hair colour pattern
|
HET
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
FACS / CD4 Effector
|
HET
|
5f:4m
|
|
|
NotProcessed |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Echo / LVIDd
|
HET
|
8f:m
|
Linear Mixed Model framework, LME, including Weight
|
0.607
|
Successful |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Adult LacZ / Bone
|
HET
|
1f:1m
|
|
|
NotProcessed |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Combined SHIRPA and Dysmorphology / Hindlimb nail - length
|
HET
|
8f:8m
|
|
|
NotProcessed |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Clinical Chemistry / Aspartate aminotransferase
|
HET
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.0573
|
Successful |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Clinical Chemistry / Aspartate aminotransferase
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.444
|
Successful |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Forepaw digit morphology
|
HET
|
7f:7m
|
|
|
NotProcessed |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Hematology / Eosinophil cell count
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.268
|
Successful |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Combined SHIRPA and Dysmorphology / Vocalization
|
HET
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Hematology / Hemoglobin
|
HET
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.00161
|
Successful |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Hematology / Hemoglobin
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.358
|
Successful |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
FACS / DC Total
|
HET
|
5f:4m
|
|
|
NotProcessed |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Adult LacZ / Aorta
|
HET
|
1f:1m
|
|
|
NotProcessed |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Indirect Calorimetry / Heat production (metabolic rate)
|
HET
|
f:553m
|
|
|
NotProcessed |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Indirect Calorimetry / Heat production (metabolic rate)
|
HET
|
f:154m
|
|
|
NotProcessed |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
X-ray / Syndactylism
|
HET
|
7f:7m
|
|
|
NotProcessed |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
X-ray / Syndactylism
|
HET
|
5f:5m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Open Field / Whole arena resting time
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.878
|
Successful |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Combined SHIRPA and Dysmorphology / Teeth presence
|
HET
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Forelimb morphology
|
HET
|
7f:7m
|
|
|
NotProcessed |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Eye Morphology / Optic Disc
|
HET
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Eye Morphology / Optic Disc
|
HET
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Combined SHIRPA and Dysmorphology / Coat - color pattern - back
|
HET
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Eye Morphology / Narrow eye opening
|
HET
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Eye Morphology / Narrow eye opening
|
HET
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Clinical Chemistry / Glycerol
|
HET
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.670
|
Successful |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Heart Weight / Heart weight
|
HET
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.345
|
Successful |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Organ Weight / Heart weight
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.632
|
Successful |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Vibrissae size
|
HET
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Dorsal skin appearance
|
HET
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Vibrissae colour
|
HET
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Combined SHIRPA and Dysmorphology / Coat - hair texture / appearance - back
|
HET
|
8f:8m
|
|
|
NotProcessed |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Hindpaw footpad size
|
HET
|
7f:7m
|
|
|
NotProcessed |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - S
|
HET
|
8f:8m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.886
|
Successful |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Eye Morphology / Pupil Shape
|
HET
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Eye Morphology / Pupil Shape
|
HET
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Intraperitoneal glucose tolerance test (IPGTT) / Blood glucose concentration
|
HET
|
40f:40m
|
|
|
NotProcessed |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Intraperitoneal glucose tolerance test (IPGTT) / Blood glucose concentration
|
HET
|
35f:31m
|
|
|
NotProcessed |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Open Field / Periphery average speed
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.865
|
Successful |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
X-ray / Cervical processes
|
HET
|
7f:7m
|
Fisher Exact Test framework
|
0.213
|
Successful |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Combined SHIRPA and Dysmorphology / Transfer arousal
|
HET
|
8f:8m
|
|
|
NotProcessed |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
FACS / NKT Effector
|
HET
|
5f:4m
|
|
|
NotProcessed |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
FACS / Neutrophils
|
HET
|
5f:4m
|
|
|
NotProcessed |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Paw coat/hair colour pattern
|
HET
|
7f:7m
|
|
|
NotProcessed |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Echo / Stroke Volume
|
HET
|
8f:m
|
Linear Mixed Model framework, LME, including Weight
|
0.587
|
Successful |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Three-point Bend / Yield Load
|
HET
|
2f:m
|
|
|
NotProcessed |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
X-ray / Comment on XRay image
|
HET
|
2f:m
|
|
|
NotProcessed |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
X-ray / Comment on XRay image
|
HET
|
7f:7m
|
|
|
NotProcessed |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Hematology / Monocyte differential count
|
HET
|
8f:8m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
2.58×10-06
|
Successful |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Hindpaw nail count
|
HET
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
FACS / NKT Resting
|
HET
|
5f:4m
|
|
|
NotProcessed |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Cortical Bone MicroCT / Cortical Thickness
|
HET
|
2f:m
|
|
|
NotProcessed |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Body Composition (DEXA lean/fat) / Lean/Body weight
|
HET
|
7f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.159
|
Successful |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Body Composition (DEXA lean/fat) / Lean/Body weight
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.268
|
Successful |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Buffy coat peripheral blood leukocyte immunophenotyping / NKT cell percentage
|
HET
|
7f:7m
|
|
|
NotProcessed |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Open Field / Distance travelled - total
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.965
|
Successful |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Combined SHIRPA and Dysmorphology / Snout size
|
HET
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Auditory Brain Stem Response / Click-evoked ABR threshold
|
HET
|
2f:2m
|
|
|
NotProcessed |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Auditory Brain Stem Response / Click-evoked ABR threshold
|
HET
|
2f:2m
|
Reference Range Plus Test framework; quantile = 0.95 (Tails probability = 0.025)
|
0.0462
|
Successful |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Eye Morphology / Synechia
|
HET
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Eye Morphology / Synechia
|
HET
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Auditory Brain Stem Response / 24kHz-evoked ABR Threshold
|
HET
|
2f:2m
|
|
|
NotProcessed |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Auditory Brain Stem Response / 24kHz-evoked ABR Threshold
|
HET
|
2f:2m
|
Reference Range Plus Test framework; quantile = 0.95 (Tails probability = 0.025)
|
0.0256
|
Successful |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Clinical Chemistry / Total cholesterol
|
HET
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.00514
|
Successful |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Clinical Chemistry / Total cholesterol
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.145
|
Successful |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Hindpaw
|
HET
|
7f:7m
|
|
|
NotProcessed |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Clinical Chemistry / Albumin
|
HET
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.00623
|
Successful |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Clinical Chemistry / Albumin
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.256
|
Successful |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Intraperitoneal glucose tolerance test (IPGTT) / Initial response to glucose challenge
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0361
|
Successful |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Intraperitoneal glucose tolerance test (IPGTT) / Initial response to glucose challenge
|
HET
|
7f:6m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0888
|
Successful |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Electrocardiogram (ECG) / HR
|
HET
|
8f:8m
|
Linear Model Using Generalized Least Squares framework, GLS, including Weight
|
0.814
|
Successful |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Antigen Specific Immunoglobulin Assay / TetC specific IgG1
|
HET
|
f:3m
|
|
|
NotProcessed |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
X-ray / Transitional vertebrae
|
HET
|
7f:7m
|
Fisher Exact Test framework
|
0.105
|
Successful |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
X-ray / Pelvis
|
HET
|
7f:7m
|
Fisher Exact Test framework
|
0.0503
|
Successful |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
X-ray / Pelvis
|
HET
|
5f:5m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
FACS / B1 Total
|
HET
|
5f:4m
|
|
|
NotProcessed |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Adult LacZ / Lung
|
HET
|
1f:1m
|
|
|
NotProcessed |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Pinna rotation
|
HET
|
7f:7m
|
|
|
NotProcessed |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
X-ray / Shape of spine
|
HET
|
7f:7m
|
Fisher Exact Test framework
|
0.208
|
Successful |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Eye Morphology / Eyelid morphology
|
HET
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Eye Morphology / Eyelid morphology
|
HET
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Combined SHIRPA and Dysmorphology / Forelimb digit - shape
|
HET
|
8f:8m
|
|
|
NotProcessed |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Adult LacZ / Spleen
|
HET
|
1f:1m
|
|
|
NotProcessed |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Hematology / Mean cell volume
|
HET
|
7f:7m
|
|
|
NotProcessed |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Hematology / Mean cell volume
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.00815
|
Successful |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Combined SHIRPA and Dysmorphology / Coat - color - back
|
HET
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Vertebra Compression / Vertebra Max Load
|
HET
|
2f:m
|
|
|
NotProcessed |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Femoral Microradiography / Femoral Bone Mineral Content
|
HET
|
2f:m
|
|
|
NotProcessed |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Open Field / Center permanence time
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.616
|
Successful |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Grip Strength / Forelimb grip strength measurement
|
HET
|
24f:24m
|
|
|
NotProcessed |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Grip Strength / Forelimb grip strength measurement
|
HET
|
24f:21m
|
|
|
NotProcessed |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Combined SHIRPA and Dysmorphology / Hindpaw - size
|
HET
|
8f:8m
|
|
|
NotProcessed |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Open Field / Whole arena permanence
|
HET
|
8f:8m
|
|
|
NotProcessed |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
FACS / Eosinophils
|
HET
|
5f:4m
|
|
|
NotProcessed |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Combined SHIRPA and Dysmorphology / Upper lip morphology
|
HET
|
8f:8m
|
|
|
NotProcessed |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Combined SHIRPA and Dysmorphology / Locomotor activity
|
HET
|
8f:8m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.0943
|
Successful |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Buffy coat peripheral blood leukocyte immunophenotyping / B cell CD19+ percentage
|
HET
|
7f:7m
|
|
|
NotProcessed |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Pinna skin colour
|
HET
|
7f:7m
|
|
|
NotProcessed |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Salmonella Challenge / Spleen Weight
|
HET
|
f:3m
|
|
|
NotProcessed |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Positional passivity
|
HET
|
7f:7m
|
|
|
NotProcessed |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Adult LacZ / Lower Urinary Tract
|
HET
|
1f:1m
|
|
|
NotProcessed |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Forepaw nail length
|
HET
|
7f:7m
|
|
|
NotProcessed |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Head coat/hair colour pattern
|
HET
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Forepaw
|
HET
|
7f:7m
|
|
|
NotProcessed |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Indirect Calorimetry / Ambulatory activity (no. of beam cuts)
|
HET
|
f:154m
|
|
|
NotProcessed |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Indirect Calorimetry / Ambulatory activity (no. of beam cuts)
|
HET
|
f:553m
|
|
|
NotProcessed |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Digit coat/hair length
|
HET
|
7f:7m
|
|
|
NotProcessed |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Adult LacZ / Ovary
|
HET
|
1f:1m
|
|
|
NotProcessed |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Electrocardiogram (ECG) / HRV
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.927
|
Successful |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI1
|
HET
|
8f:8m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.454
|
Successful |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Eye Morphology / Retinal Blood Vessels
|
HET
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Eye Morphology / Retinal Blood Vessels
|
HET
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Trabecular Bone MicroCT / Trabecular Number (mm-1)
|
HET
|
2f:m
|
|
|
NotProcessed |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP4
|
HET
|
8f:8m
|
|
|
NotProcessed |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Adult LacZ / Uterus
|
HET
|
1f:1m
|
|
|
NotProcessed |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
X-ray / Mandibles
|
HET
|
7f:7m
|
|
|
NotProcessed |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
X-ray / Mandibles
|
HET
|
5f:5m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Vibrissae
|
HET
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Pinna touch reflex
|
HET
|
7f:7m
|
|
|
NotProcessed |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Ventral coat/hair presence
|
HET
|
7f:7m
|
Fisher Exact Test framework
|
0.394
|
Successful |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Combined SHIRPA and Dysmorphology / Skin color - back paws
|
HET
|
8f:8m
|
|
|
NotProcessed |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Salmonella Challenge / Caecal Contents Counts in 20 micro litres
|
HET
|
f:3m
|
|
|
NotProcessed |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Mouth morphology
|
HET
|
7f:7m
|
|
|
NotProcessed |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Combined SHIRPA and Dysmorphology / Skin color - whole body
|
HET
|
8f:8m
|
|
|
NotProcessed |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
X-ray / Number of digits
|
HET
|
7f:7m
|
|
|
NotProcessed |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
X-ray / Number of digits
|
HET
|
5f:5m
|
|
|
NotProcessed |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Combined SHIRPA and Dysmorphology / Coat - hair distribution - abdomen
|
HET
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Open Field / Center distance travelled series
|
HET
|
32f:32m
|
|
|
NotProcessed |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Dysmorphology comment
|
HET
|
f:2m
|
|
|
NotProcessed |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Open Field / Whole arena resting time series
|
HET
|
32f:32m
|
|
|
NotProcessed |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Limb coat/hair presence
|
HET
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
FACS / NKT Total
|
HET
|
5f:4m
|
|
|
NotProcessed |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Incisors
|
HET
|
7f:7m
|
|
|
NotProcessed |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Adult LacZ / Brainstem
|
HET
|
1f:1m
|
|
|
NotProcessed |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Combined SHIRPA and Dysmorphology / Hindlimb nail - shape
|
HET
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Combined SHIRPA and Dysmorphology / Coat - hair distribution - head
|
HET
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Adult LacZ / Oral epithelium
|
HET
|
1f:1m
|
|
|
NotProcessed |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Hindpaw size
|
HET
|
7f:7m
|
|
|
NotProcessed |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Vertebral Microradiography / Vertebral Bone Mineral Content
|
HET
|
2f:m
|
|
|
NotProcessed |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Clinical Chemistry / Fructosamine
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.0666
|
Successful |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Clinical Chemistry / Fructosamine
|
HET
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.0754
|
Successful |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Clinical Chemistry / Alkaline phosphatase
|
HET
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.0430
|
Successful |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Clinical Chemistry / Alkaline phosphatase
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.129
|
Successful |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Eye Morphology / Eye Hemorrhage or Blood Presence
|
HET
|
7f:7m
|
|
|
NotProcessed |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Eye Morphology / Eye Hemorrhage or Blood Presence
|
HET
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Hematology / Monocyte cell count
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.00554
|
Successful |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
X-ray / Teeth
|
HET
|
5f:5m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
X-ray / Teeth
|
HET
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Paw coat/hair length
|
HET
|
7f:7m
|
|
|
NotProcessed |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Echo / End-Systolic Diameter
|
HET
|
8f:m
|
Linear Mixed Model framework, LME, including Weight
|
0.420
|
Successful |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Cortical Bone MicroCT / Internal Diameter
|
HET
|
2f:m
|
|
|
NotProcessed |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Buffy coat peripheral blood leukocyte immunophenotyping / CD4+CD44+CD62L- percentage
|
HET
|
7f:7m
|
|
|
NotProcessed |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Adult LacZ / White Adipose Tissue
|
HET
|
1f:1m
|
|
|
NotProcessed |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Body Weight / Body weight
|
HET
|
99f:104m
|
|
|
NotProcessed |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Body Weight / Body weight
|
HET
|
74f:84m
|
|
|
NotProcessed |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
FACS / B cell total
|
HET
|
5f:4m
|
|
|
NotProcessed |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Antigen Specific Immunoglobulin Assay / TetC specific IgG2
|
HET
|
f:3m
|
|
|
NotProcessed |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Eye Morphology / Fusion between cornea and lens
|
HET
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Eye Morphology / Fusion between cornea and lens
|
HET
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Combined SHIRPA and Dysmorphology / Coat - color - head
|
HET
|
8f:8m
|
|
|
NotProcessed |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Hematology / Mean corpuscular hemoglobin
|
HET
|
7f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
2.29×10-08
|
Successful |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Hematology / Mean corpuscular hemoglobin
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.00253
|
Successful |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Tail coat/hair presence
|
HET
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Forepaw size
|
HET
|
7f:7m
|
|
|
NotProcessed |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Combined SHIRPA and Dysmorphology / Hindlimb digit - shape
|
HET
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Combined SHIRPA and Dysmorphology / Forepaw - size
|
HET
|
8f:8m
|
|
|
NotProcessed |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Hematology / Large Unstained Cell (LUC) differential count
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.00623
|
Successful |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Intraperitoneal glucose tolerance test (IPGTT) / Fasted blood glucose concentration
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.129
|
Successful |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Intraperitoneal glucose tolerance test (IPGTT) / Fasted blood glucose concentration
|
HET
|
7f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.490
|
Successful |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Clinical Chemistry / Total bilirubin
|
HET
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.230
|
Successful |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Clinical Chemistry / Total bilirubin
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.467
|
Successful |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Indirect Calorimetry / Total activity (no. of fine movement + no. of beam cuts)
|
HET
|
f:154m
|
|
|
NotProcessed |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Indirect Calorimetry / Total activity (no. of fine movement + no. of beam cuts)
|
HET
|
f:553m
|
|
|
NotProcessed |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Electrocardiogram (ECG) / CV
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.908
|
Successful |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
X-ray / Fusion of ribs
|
HET
|
7f:7m
|
|
|
NotProcessed |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
X-ray / Fusion of ribs
|
HET
|
5f:5m
|
|
|
NotProcessed |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Limb grasping
|
HET
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Body Composition (DEXA lean/fat) / BMC/Body weight
|
HET
|
7f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.362
|
Successful |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Body Composition (DEXA lean/fat) / BMC/Body weight
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.781
|
Successful |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Combined SHIRPA and Dysmorphology / Lower lip morphology
|
HET
|
8f:8m
|
|
|
NotProcessed |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Salmonella Challenge / Spleen Counts in 20 micro litres
|
HET
|
f:3m
|
|
|
NotProcessed |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Adult LacZ / Brown adipose tissue
|
HET
|
1f:1m
|
|
|
NotProcessed |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Head coat/hair appearance
|
HET
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Forepaw nail count
|
HET
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Vertebra Compression / Vertebra Stiffness
|
HET
|
2f:m
|
|
|
NotProcessed |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Open Field / Center resting time
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.656
|
Successful |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Eye Morphology / Retinal Blood Vessels Structure
|
HET
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Eye Morphology / Retinal Blood Vessels Structure
|
HET
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
X-ray / Joints
|
HET
|
5f:5m
|
Fisher Exact Test framework
|
0.0110
|
Successful |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
X-ray / Joints
|
HET
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Grip Strength / Forelimb and hindlimb grip strength measurement
|
HET
|
24f:24m
|
|
|
NotProcessed |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Grip Strength / Forelimb and hindlimb grip strength measurement
|
HET
|
24f:21m
|
|
|
NotProcessed |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Adult LacZ / Large Intestine
|
HET
|
1f:1m
|
|
|
NotProcessed |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Pinna skin appearance
|
HET
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Combined SHIRPA and Dysmorphology / Gait
|
HET
|
8f:8m
|
Fisher Exact Test framework
|
4.76×10-07
|
Successful |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
X-ray / Fusion of processes
|
HET
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Hematology / Red blood cell distribution width
|
HET
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
1.66×10-05
|
Successful |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Hematology / Red blood cell distribution width
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.609
|
Successful |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Combined SHIRPA and Dysmorphology / Ears
|
HET
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
FACS / CD8 T cells total
|
HET
|
5f:4m
|
|
|
NotProcessed |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Open Field / Periphery average speed series
|
HET
|
32f:32m
|
|
|
NotProcessed |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Adult LacZ / Brain
|
HET
|
1f:1m
|
|
|
NotProcessed |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Snout size
|
HET
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
X-ray / Tibia length
|
HET
|
5f:5m
|
Linear Mixed Model framework, LME, including Weight
|
0.485
|
Successful |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP3
|
HET
|
8f:8m
|
|
|
NotProcessed |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP4_S
|
HET
|
8f:8m
|
|
|
NotProcessed |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Open Field / Whole arena average speed
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.965
|
Successful |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Three-point Bend / Max Load
|
HET
|
2f:m
|
|
|
NotProcessed |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Dorsal coat/hair length
|
HET
|
7f:7m
|
|
|
NotProcessed |
Usp22tm1b(KOMP)Wtsi
|
MRC Harwell
|
Combined SHIRPA and Dysmorphology / Skin color - tail
|
HET
|
8f:8m
|
|
|
NotProcessed |
Usp22tm1a(KOMP)Wtsi
|
WTSI
|
Trabecular Bone MicroCT / Bone Volume/Tissue Volume (%)
|
HET
|
2f:m
|
|
|
NotProcessed |