All behavior/neurological phenotype, nervous system phenotype data for Cib2

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Allele Center Procedure / Parameter Zygosity Mutants Statistical
Method
P Value Status Graph
Cib2tm1b(EUCOMM)Wtsi MRC Harwell Open Field / Periphery resting time HOM 8f:13m Mixed Model framework, linear mixed-effects model, equation withWeight 0.31553 Success
Cib2tm1b(EUCOMM)Wtsi MRC Harwell Open Field / Center permanence time HOM 8f:13m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.37354 Success
Cib2tm1b(EUCOMM)Wtsi MRC Harwell Open Field / Whole arena resting time HOM 8f:13m Mixed Model framework, linear mixed-effects model, equation withWeight 0.36143 Success
Cib2tm1b(EUCOMM)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Activity (body position) HOM 9f:13m Fisher Exact Test framework 1.0000 Success
Cib2tm1b(EUCOMM)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Head bobbing HOM 9f:13m Fisher Exact Test framework 1.0000 Success
Cib2tm1b(EUCOMM)Wtsi MRC Harwell Grip Strength / Forelimb grip strength normalised against body weight HOM 9f:13m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.072447 Success
Cib2tm1b(EUCOMM)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Trunk curl HOM 9f:13m Fisher Exact Test framework 1.0000 Success
Cib2tm1b(EUCOMM)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Locomotor activity HOM 9f:12m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.053530 Success
Cib2tm1b(EUCOMM)Wtsi MRC Harwell Open Field / Center resting time HOM 8f:13m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.79022 Success
Cib2tm1b(EUCOMM)Wtsi MRC Harwell Eye Morphology / Optic Disc HOM 9f:13m Fisher Exact Test framework 1.0000 Success
Cib2tm1b(EUCOMM)Wtsi MRC Harwell Open Field / Center average speed HOM 8f:13m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.52751 Success
Cib2tm1b(EUCOMM)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Contact righting HOM 9f:13m Fisher Exact Test framework 1.0000 Success
Cib2tm1b(EUCOMM)Wtsi MRC Harwell Grip Strength / Forelimb and hindlimb grip strength normalised against body weight HOM 9f:13m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.26878 Success
Cib2tm1b(EUCOMM)Wtsi MRC Harwell Open Field / Distance travelled - total HOM 8f:13m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.69286 Success
Cib2tm1b(EUCOMM)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Unexpected behaviors HOM 9f:13m Fisher Exact Test framework 1.0000 Success
Cib2tm1b(EUCOMM)Wtsi MRC Harwell Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - Global HOM 8f:13m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.00010208 Success
Cib2tm1b(EUCOMM)Wtsi MRC Harwell Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - Global HOM 1f:0m Not processed 1.0000 FAILED - Not enough mutant or control data
Cib2tm1b(EUCOMM)Wtsi MRC Harwell Open Field / Periphery permanence time HOM 8f:13m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.34093 Success
Cib2tm1b(EUCOMM)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Gait HOM 9f:13m Fisher Exact Test framework 1.0000 Success
Cib2tm1b(EUCOMM)Wtsi MRC Harwell Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI1 HOM 8f:13m Mixed Model framework, generalized least squares, equation withoutWeight 0.10514 Success
Cib2tm1b(EUCOMM)Wtsi MRC Harwell Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI1 HOM 1f:0m Not processed 1.0000 FAILED - Not enough mutant or control data
Cib2tm1b(EUCOMM)Wtsi MRC Harwell Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI3 HOM 8f:13m Mixed Model framework, linear mixed-effects model, equation withoutWeight 5.8733E-05 Success
Cib2tm1b(EUCOMM)Wtsi MRC Harwell Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI3 HOM 1f:0m Not processed 1.0000 FAILED - Not enough mutant or control data
Cib2tm1b(EUCOMM)Wtsi MRC Harwell Open Field / Latency to center entry HOM 8f:13m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.46164 Success
Cib2tm1b(EUCOMM)Wtsi MRC Harwell Open Field / Percentage center time HOM 8f:13m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.37353 Success
Cib2tm1b(EUCOMM)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Aggression HOM 9f:13m Fisher Exact Test framework 0.094621 Success
Cib2tm1b(EUCOMM)Wtsi MRC Harwell Open Field / Number of center entries HOM 8f:13m Mixed Model framework, linear mixed-effects model, equation withWeight 0.75773 Success
Cib2tm1b(EUCOMM)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Tremor HOM 9f:13m Fisher Exact Test framework 1.2425E-05 Success
Cib2tm1b(EUCOMM)Wtsi MRC Harwell Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI2 HOM 8f:13m Mixed Model framework, linear mixed-effects model, equation withoutWeight 5.0442E-05 Success
Cib2tm1b(EUCOMM)Wtsi MRC Harwell Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI2 HOM 1f:0m Not processed 1.0000 FAILED - Not enough mutant or control data
Cib2tm1b(EUCOMM)Wtsi MRC Harwell Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - S HOM 8f:13m Mixed Model framework, linear mixed-effects model, equation withoutWeight 5.4675E-14 Success
Cib2tm1b(EUCOMM)Wtsi MRC Harwell Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - S HOM 1f:0m Not processed 1.0000 FAILED - Not enough mutant or control data
Cib2tm1b(EUCOMM)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Startle response HOM 9f:13m Fisher Exact Test framework 3.2384E-35 Success
Cib2tm1b(EUCOMM)Wtsi MRC Harwell Grip Strength / Forelimb grip strength measurement mean HOM 9f:13m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.54578 Success
Cib2tm1b(EUCOMM)Wtsi MRC Harwell Open Field / Periphery average speed HOM 8f:13m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.63031 Success
Cib2tm1b(EUCOMM)Wtsi MRC Harwell Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI4 HOM 8f:13m Mixed Model framework, linear mixed-effects model, equation withoutWeight 5.6122E-06 Success
Cib2tm1b(EUCOMM)Wtsi MRC Harwell Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI4 HOM 1f:0m Not processed 1.0000 FAILED - Not enough mutant or control data
Cib2tm1b(EUCOMM)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Limb grasp HOM 9f:13m Fisher Exact Test framework 0.00011207 Success
Cib2tm1b(EUCOMM)Wtsi MRC Harwell Eye Morphology / Pupil Light Response HOM 9f:13m Fisher Exact Test framework 1.0000 Success
Cib2tm1b(EUCOMM)Wtsi MRC Harwell Open Field / Whole arena average speed HOM 8f:13m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.69321 Success
Cib2tm1b(EUCOMM)Wtsi MRC Harwell Open Field / Center distance travelled HOM 8f:13m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.44417 Success
Cib2tm1b(EUCOMM)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Vocalization HOM 9f:13m Fisher Exact Test framework 1.0000 Success
Cib2tm1b(EUCOMM)Wtsi MRC Harwell Open Field / Periphery distance travelled HOM 8f:13m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.99622 Success
Cib2tm1b(EUCOMM)Wtsi MRC Harwell Grip Strength / Forelimb and hindlimb grip strength measurement mean HOM 9f:13m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.84438 Success

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