Thsd1tm1.1(KOMP)Vlcg
|
JAX
|
Electroconvulsive Threshold Testing / mA threshold inducing clonic seizure
|
HOM
|
2f:1m
|
|
|
NotProcessed |
Thsd1tm1.1(KOMP)Vlcg
|
JAX
|
Electroconvulsive Threshold Testing / mA threshold inducing clonic seizure
|
HOM
|
5f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.0429
|
Successful |
Thsd1tm1.1(KOMP)Vlcg
|
JAX
|
Open Field - centre start / Whole arena average speed
|
HOM
|
8f:9m
|
Linear Mixed Model framework, LME, not including Weight
|
0.380
|
Successful |
Thsd1tm1.1(KOMP)Vlcg
|
JAX
|
Hole-board Exploration / Holepoke sequence
|
HOM
|
245f:364m
|
|
|
NotProcessed |
Thsd1tm1.1(KOMP)Vlcg
|
JAX
|
Sleep Wake / Light sleep bout lengths standard deviation
|
HOM
|
7f:9m
|
Linear Mixed Model framework, LME, including Weight
|
0.0516
|
Successful |
Thsd1tm1.1(KOMP)Vlcg
|
JAX
|
Combined SHIRPA and Dysmorphology / Activity (body position)
|
HOM
|
8f:9m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Thsd1tm1.1(KOMP)Vlcg
|
JAX
|
Combined SHIRPA and Dysmorphology / Head bobbing
|
HOM
|
8f:9m
|
|
|
NotProcessed |
Thsd1tm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP1
|
HOM
|
6f:9m
|
|
|
NotProcessed |
Thsd1tm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP1
|
HOM
|
2f:m
|
|
|
NotProcessed |
Thsd1tm1.1(KOMP)Vlcg
|
JAX
|
Light-Dark Test / Percent time in light
|
HOM
|
8f:9m
|
Linear Mixed Model framework, LME, not including Weight
|
0.581
|
Successful |
Thsd1tm1.1(KOMP)Vlcg
|
JAX
|
Open Field - centre start / Center average speed
|
HOM
|
8f:9m
|
Linear Mixed Model framework, LME, not including Weight
|
0.800
|
Successful |
Thsd1tm1.1(KOMP)Vlcg
|
JAX
|
Combined SHIRPA and Dysmorphology / Trunk curl
|
HOM
|
8f:9m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Thsd1tm1.1(KOMP)Vlcg
|
JAX
|
Open Field - centre start / Center permanence time
|
HOM
|
8f:9m
|
Linear Mixed Model framework, LME, not including Weight
|
0.518
|
Successful |
Thsd1tm1.1(KOMP)Vlcg
|
JAX
|
Light-Dark Test / Side changes
|
HOM
|
8f:9m
|
Linear Mixed Model framework, LME, including Weight
|
0.957
|
Successful |
Thsd1tm1.1(KOMP)Vlcg
|
JAX
|
Hole-board Exploration / Total holepokes
|
HOM
|
8f:9m
|
Linear Mixed Model framework, LME, including Weight
|
0.321
|
Successful |
Thsd1tm1.1(KOMP)Vlcg
|
JAX
|
Sleep Wake / Dark sleep bout lengths mean
|
HOM
|
7f:9m
|
Linear Mixed Model framework, LME, including Weight
|
0.138
|
Successful |
Thsd1tm1.1(KOMP)Vlcg
|
JAX
|
Combined SHIRPA and Dysmorphology / Unexpected behaviors
|
HOM
|
8f:9m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Thsd1tm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP2
|
HOM
|
2f:m
|
|
|
NotProcessed |
Thsd1tm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP2
|
HOM
|
6f:9m
|
|
|
NotProcessed |
Thsd1tm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - Global
|
HOM
|
2f:m
|
|
|
NotProcessed |
Thsd1tm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - Global
|
HOM
|
6f:9m
|
Linear Mixed Model framework, LME, including Weight
|
0.132
|
Successful |
Thsd1tm1.1(KOMP)Vlcg
|
JAX
|
Light-Dark Test / Light side time spent
|
HOM
|
8f:9m
|
Linear Mixed Model framework, LME, including Weight
|
0.216
|
Successful |
Thsd1tm1.1(KOMP)Vlcg
|
JAX
|
Open Field - centre start / Periphery distance travelled
|
HOM
|
8f:9m
|
Linear Mixed Model framework, LME, not including Weight
|
0.245
|
Successful |
Thsd1tm1.1(KOMP)Vlcg
|
JAX
|
Open Field - centre start / Whole arena resting time
|
HOM
|
8f:9m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0915
|
Successful |
Thsd1tm1.1(KOMP)Vlcg
|
JAX
|
Combined SHIRPA and Dysmorphology / Aggression
|
HOM
|
8f:9m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Thsd1tm1.1(KOMP)Vlcg
|
JAX
|
Open Field - centre start / Number of Rears
|
HOM
|
32f:36m
|
|
|
NotProcessed |
Thsd1tm1.1(KOMP)Vlcg
|
JAX
|
Light-Dark Test / Time mobile light side
|
HOM
|
8f:9m
|
Linear Mixed Model framework, LME, not including Weight
|
0.988
|
Successful |
Thsd1tm1.1(KOMP)Vlcg
|
JAX
|
Grip Strength / Forelimb grip strength measurement mean
|
HOM
|
8f:9m
|
Linear Mixed Model framework, LME, including Weight
|
0.00944
|
Successful |
Thsd1tm1.1(KOMP)Vlcg
|
JAX
|
Combined SHIRPA and Dysmorphology / Startle response
|
HOM
|
8f:9m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Thsd1tm1.1(KOMP)Vlcg
|
JAX
|
Sleep Wake / Breath rate during sleep standard deviation
|
HOM
|
7f:9m
|
Linear Mixed Model framework, LME, not including Weight
|
0.493
|
Successful |
Thsd1tm1.1(KOMP)Vlcg
|
JAX
|
Open Field - centre start / Percentage center time
|
HOM
|
8f:9m
|
Linear Mixed Model framework, LME, not including Weight
|
0.518
|
Successful |
Thsd1tm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - BN
|
HOM
|
6f:9m
|
|
|
NotProcessed |
Thsd1tm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - BN
|
HOM
|
2f:m
|
|
|
NotProcessed |
Thsd1tm1.1(KOMP)Vlcg
|
JAX
|
Open Field - centre start / Distance travelled
|
HOM
|
32f:36m
|
|
|
NotProcessed |
Thsd1tm1.1(KOMP)Vlcg
|
JAX
|
Combined SHIRPA and Dysmorphology / Vocalization
|
HOM
|
8f:9m
|
Fisher Exact Test framework
|
0.620
|
Successful |
Thsd1tm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP3_S
|
HOM
|
2f:m
|
|
|
NotProcessed |
Thsd1tm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP3_S
|
HOM
|
6f:9m
|
|
|
NotProcessed |
Thsd1tm1.1(KOMP)Vlcg
|
JAX
|
Tail Suspension / Time immobile
|
HOM
|
1f:m
|
|
|
NotProcessed |
Thsd1tm1.1(KOMP)Vlcg
|
JAX
|
Tail Suspension / Time immobile
|
HOM
|
6f:9m
|
Linear Mixed Model framework, LME, including Weight
|
0.0998
|
Successful |
Thsd1tm1.1(KOMP)Vlcg
|
JAX
|
Combined SHIRPA and Dysmorphology / Touch escape
|
HOM
|
6f:9m
|
|
|
NotProcessed |
Thsd1tm1.1(KOMP)Vlcg
|
JAX
|
Sleep Wake / Sleep daily percent
|
HOM
|
7f:9m
|
Linear Mixed Model framework, LME, not including Weight
|
0.857
|
Successful |
Thsd1tm1.1(KOMP)Vlcg
|
JAX
|
Light-Dark Test / Dark side time spent
|
HOM
|
8f:9m
|
Linear Mixed Model framework, LME, including Weight
|
0.216
|
Successful |
Thsd1tm1.1(KOMP)Vlcg
|
JAX
|
Grip Strength / Forelimb and hindlimb grip strength measurement mean
|
HOM
|
8f:9m
|
Linear Mixed Model framework, LME, including Weight
|
0.0119
|
Successful |
Thsd1tm1.1(KOMP)Vlcg
|
JAX
|
Sleep Wake / Sleep light phase percent
|
HOM
|
7f:9m
|
Linear Mixed Model framework, LME, including Weight
|
0.332
|
Successful |
Thsd1tm1.1(KOMP)Vlcg
|
JAX
|
Open Field - centre start / Number of rears - total
|
HOM
|
8f:9m
|
Linear Mixed Model framework, LME, including Weight
|
0.319
|
Successful |
Thsd1tm1.1(KOMP)Vlcg
|
JAX
|
Grip Strength / Forelimb grip strength measurement
|
HOM
|
24f:27m
|
|
|
NotProcessed |
Thsd1tm1.1(KOMP)Vlcg
|
JAX
|
Rotarod / Latency to fall
|
HOM
|
40f:45m
|
|
|
NotProcessed |
Thsd1tm1.1(KOMP)Vlcg
|
JAX
|
Tail Suspension / Latency to immobility
|
HOM
|
1f:m
|
|
|
NotProcessed |
Thsd1tm1.1(KOMP)Vlcg
|
JAX
|
Tail Suspension / Latency to immobility
|
HOM
|
6f:9m
|
Linear Mixed Model framework, LME, including Weight
|
0.993
|
Successful |
Thsd1tm1.1(KOMP)Vlcg
|
JAX
|
Sleep Wake / Peak wake with respect to dark onset median
|
HOM
|
7f:9m
|
Linear Mixed Model framework, LME, including Weight
|
0.858
|
Successful |
Thsd1tm1.1(KOMP)Vlcg
|
JAX
|
Grip Strength / Forelimb grip strength normalised against body weight
|
HOM
|
8f:9m
|
Linear Mixed Model framework, LME, not including Weight
|
0.00467
|
Successful |
Thsd1tm1.1(KOMP)Vlcg
|
JAX
|
Combined SHIRPA and Dysmorphology / Locomotor activity
|
HOM
|
8f:9m
|
Linear Mixed Model framework, LME, including Weight
|
0.0376
|
Successful |
Thsd1tm1.1(KOMP)Vlcg
|
JAX
|
Eye Morphology / Optic Disc
|
HOM
|
8f:9m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Thsd1tm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP2_S
|
HOM
|
6f:9m
|
|
|
NotProcessed |
Thsd1tm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP2_S
|
HOM
|
2f:m
|
|
|
NotProcessed |
Thsd1tm1.1(KOMP)Vlcg
|
JAX
|
Combined SHIRPA and Dysmorphology / Tail elevation
|
HOM
|
8f:9m
|
|
|
NotProcessed |
Thsd1tm1.1(KOMP)Vlcg
|
JAX
|
Open Field - centre start / Periphery average speed
|
HOM
|
8f:9m
|
Linear Mixed Model framework, LME, not including Weight
|
0.213
|
Successful |
Thsd1tm1.1(KOMP)Vlcg
|
JAX
|
Light-Dark Test / Time mobile dark side
|
HOM
|
8f:9m
|
Linear Mixed Model framework, LME, including Weight
|
0.453
|
Successful |
Thsd1tm1.1(KOMP)Vlcg
|
JAX
|
Light-Dark Test / Fecal boli
|
HOM
|
8f:9m
|
Linear Mixed Model framework, LME, including Weight
|
0.407
|
Successful |
Thsd1tm1.1(KOMP)Vlcg
|
JAX
|
Combined SHIRPA and Dysmorphology / Contact righting
|
HOM
|
8f:9m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Thsd1tm1.1(KOMP)Vlcg
|
JAX
|
Sleep Wake / Sleep dark phase percent
|
HOM
|
7f:9m
|
Linear Mixed Model framework, LME, including Weight
|
0.549
|
Successful |
Thsd1tm1.1(KOMP)Vlcg
|
JAX
|
Grip Strength / Forelimb and hindlimb grip strength normalised against body weight
|
HOM
|
8f:9m
|
Linear Mixed Model framework, LME, not including Weight
|
0.00839
|
Successful |
Thsd1tm1.1(KOMP)Vlcg
|
JAX
|
Grip Strength / Forelimb and hindlimb grip strength measurement
|
HOM
|
24f:27m
|
|
|
NotProcessed |
Thsd1tm1.1(KOMP)Vlcg
|
JAX
|
Open Field - centre start / Distance travelled - total
|
HOM
|
8f:9m
|
Linear Mixed Model framework, LME, not including Weight
|
0.380
|
Successful |
Thsd1tm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP1_S
|
HOM
|
6f:9m
|
|
|
NotProcessed |
Thsd1tm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP1_S
|
HOM
|
2f:m
|
|
|
NotProcessed |
Thsd1tm1.1(KOMP)Vlcg
|
JAX
|
Sleep Wake / Breath rate during sleep mean
|
HOM
|
7f:9m
|
Linear Mixed Model framework, LME, including Weight
|
0.464
|
Successful |
Thsd1tm1.1(KOMP)Vlcg
|
JAX
|
Open Field - centre start / Periphery permanence time
|
HOM
|
8f:9m
|
Linear Mixed Model framework, LME, not including Weight
|
0.519
|
Successful |
Thsd1tm1.1(KOMP)Vlcg
|
JAX
|
Combined SHIRPA and Dysmorphology / Gait
|
HOM
|
8f:9m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Thsd1tm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI1
|
HOM
|
2f:m
|
|
|
NotProcessed |
Thsd1tm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI1
|
HOM
|
6f:9m
|
Linear Mixed Model framework, LME, not including Weight
|
0.668
|
Successful |
Thsd1tm1.1(KOMP)Vlcg
|
JAX
|
Rotarod / Learning slope
|
HOM
|
8f:9m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.796
|
Successful |
Thsd1tm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP4
|
HOM
|
6f:9m
|
|
|
NotProcessed |
Thsd1tm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI3
|
HOM
|
2f:m
|
|
|
NotProcessed |
Thsd1tm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI3
|
HOM
|
6f:9m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0706
|
Successful |
Thsd1tm1.1(KOMP)Vlcg
|
JAX
|
Sleep Wake / Sleep bout lengths mean
|
HOM
|
7f:9m
|
Linear Mixed Model framework, LME, including Weight
|
0.535
|
Successful |
Thsd1tm1.1(KOMP)Vlcg
|
JAX
|
Combined SHIRPA and Dysmorphology / Tremor
|
HOM
|
8f:9m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Thsd1tm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI2
|
HOM
|
2f:m
|
|
|
NotProcessed |
Thsd1tm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI2
|
HOM
|
6f:9m
|
Linear Mixed Model framework, LME, not including Weight
|
0.143
|
Successful |
Thsd1tm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - S
|
HOM
|
2f:m
|
|
|
NotProcessed |
Thsd1tm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - S
|
HOM
|
6f:9m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0148
|
Successful |
Thsd1tm1.1(KOMP)Vlcg
|
JAX
|
Light-Dark Test / Latency to first transition into dark
|
HOM
|
8f:9m
|
Linear Mixed Model framework, LME, including Weight
|
0.0164
|
Successful |
Thsd1tm1.1(KOMP)Vlcg
|
JAX
|
Rotarod / Learning difference
|
HOM
|
8f:9m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.688
|
Successful |
Thsd1tm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI4
|
HOM
|
6f:9m
|
Linear Model Using Generalized Least Squares framework, GLS, including Weight
|
0.287
|
Successful |
Thsd1tm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP3
|
HOM
|
2f:m
|
|
|
NotProcessed |
Thsd1tm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP3
|
HOM
|
6f:9m
|
|
|
NotProcessed |
Thsd1tm1.1(KOMP)Vlcg
|
JAX
|
Sleep Wake / Dark sleep bout lengths standard deviation
|
HOM
|
7f:9m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0937
|
Successful |
Thsd1tm1.1(KOMP)Vlcg
|
JAX
|
Eye Morphology / Pupil Light Response
|
HOM
|
8f:9m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Thsd1tm1.1(KOMP)Vlcg
|
JAX
|
Combined SHIRPA and Dysmorphology / Limb grasp
|
HOM
|
8f:9m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Thsd1tm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP4_S
|
HOM
|
6f:9m
|
|
|
NotProcessed |
Thsd1tm1.1(KOMP)Vlcg
|
JAX
|
Sleep Wake / Light sleep bout lengths mean
|
HOM
|
7f:9m
|
Linear Mixed Model framework, LME, not including Weight
|
0.300
|
Successful |
Thsd1tm1.1(KOMP)Vlcg
|
JAX
|
Combined SHIRPA and Dysmorphology / Transfer arousal
|
HOM
|
8f:9m
|
|
|
NotProcessed |
Thsd1tm1.1(KOMP)Vlcg
|
JAX
|
Sleep Wake / Sleep bout lengths standard deviation
|
HOM
|
7f:9m
|
Linear Mixed Model framework, LME, including Weight
|
0.205
|
Successful |
Thsd1tm1.1(KOMP)Vlcg
|
JAX
|
Light-Dark Test / Percent time in dark
|
HOM
|
8f:9m
|
Linear Mixed Model framework, LME, not including Weight
|
0.581
|
Successful |
Thsd1tm1.1(KOMP)Vlcg
|
JAX
|
Rotarod / Average duration
|
HOM
|
8f:9m
|
Linear Mixed Model framework, LME, including Weight
|
0.696
|
Successful |
Thsd1tm1.1(KOMP)Vlcg
|
JAX
|
Open Field - centre start / Center distance travelled
|
HOM
|
8f:9m
|
Linear Mixed Model framework, LME, not including Weight
|
0.802
|
Successful |