Hspb3tm1.1(KOMP)Vlcg
|
JAX
|
Open Field - centre start / Whole arena average speed
|
HOM
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0937
|
Successful |
Hspb3tm1.1(KOMP)Vlcg
|
JAX
|
Electroconvulsive Threshold Testing / mA threshold inducing clonic seizure
|
HOM
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.235
|
Successful |
Hspb3tm1.1(KOMP)Vlcg
|
JAX
|
Hole-board Exploration / Holepoke sequence
|
HOM
|
274f:287m
|
|
|
NotProcessed |
Hspb3tm1.1(KOMP)Vlcg
|
JAX
|
Sleep Wake / Light sleep bout lengths standard deviation
|
HOM
|
8f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.770
|
Successful |
Hspb3tm1.1(KOMP)Vlcg
|
JAX
|
Combined SHIRPA and Dysmorphology / Activity (body position)
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Hspb3tm1.1(KOMP)Vlcg
|
JAX
|
Combined SHIRPA and Dysmorphology / Head bobbing
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Hspb3tm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP1
|
HOM
|
5f:8m
|
|
|
NotProcessed |
Hspb3tm1.1(KOMP)Vlcg
|
JAX
|
Light-Dark Test / Percent time in light
|
HOM
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0537
|
Successful |
Hspb3tm1.1(KOMP)Vlcg
|
JAX
|
Open Field - centre start / Center average speed
|
HOM
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.330
|
Successful |
Hspb3tm1.1(KOMP)Vlcg
|
JAX
|
Combined SHIRPA and Dysmorphology / Trunk curl
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Hspb3tm1.1(KOMP)Vlcg
|
JAX
|
Open Field - centre start / Center permanence time
|
HOM
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.605
|
Successful |
Hspb3tm1.1(KOMP)Vlcg
|
JAX
|
Light-Dark Test / Side changes
|
HOM
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.455
|
Successful |
Hspb3tm1.1(KOMP)Vlcg
|
JAX
|
Hole-board Exploration / Total holepokes
|
HOM
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.161
|
Successful |
Hspb3tm1.1(KOMP)Vlcg
|
JAX
|
Sleep Wake / Dark sleep bout lengths mean
|
HOM
|
8f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.318
|
Successful |
Hspb3tm1.1(KOMP)Vlcg
|
JAX
|
Combined SHIRPA and Dysmorphology / Unexpected behaviors
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Hspb3tm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP2
|
HOM
|
5f:8m
|
|
|
NotProcessed |
Hspb3tm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - Global
|
HOM
|
5f:8m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.813
|
Successful |
Hspb3tm1.1(KOMP)Vlcg
|
JAX
|
Light-Dark Test / Light side time spent
|
HOM
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.454
|
Successful |
Hspb3tm1.1(KOMP)Vlcg
|
JAX
|
Open Field - centre start / Periphery distance travelled
|
HOM
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.550
|
Successful |
Hspb3tm1.1(KOMP)Vlcg
|
JAX
|
Open Field - centre start / Whole arena resting time
|
HOM
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.164
|
Successful |
Hspb3tm1.1(KOMP)Vlcg
|
JAX
|
Combined SHIRPA and Dysmorphology / Aggression
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Hspb3tm1.1(KOMP)Vlcg
|
JAX
|
Open Field - centre start / Number of Rears
|
HOM
|
32f:32m
|
|
|
NotProcessed |
Hspb3tm1.1(KOMP)Vlcg
|
JAX
|
Light-Dark Test / Time mobile light side
|
HOM
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0488
|
Successful |
Hspb3tm1.1(KOMP)Vlcg
|
JAX
|
Grip Strength / Forelimb grip strength measurement mean
|
HOM
|
1f:3m
|
|
|
NotProcessed |
Hspb3tm1.1(KOMP)Vlcg
|
JAX
|
Grip Strength / Forelimb grip strength measurement mean
|
HOM
|
6f:4m
|
Linear Mixed Model framework, LME, including Weight
|
0.888
|
Successful |
Hspb3tm1.1(KOMP)Vlcg
|
JAX
|
Combined SHIRPA and Dysmorphology / Startle response
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Hspb3tm1.1(KOMP)Vlcg
|
JAX
|
Sleep Wake / Breath rate during sleep standard deviation
|
HOM
|
8f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0364
|
Successful |
Hspb3tm1.1(KOMP)Vlcg
|
JAX
|
Open Field - centre start / Percentage center time
|
HOM
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.606
|
Successful |
Hspb3tm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - BN
|
HOM
|
5f:8m
|
|
|
NotProcessed |
Hspb3tm1.1(KOMP)Vlcg
|
JAX
|
Open Field - centre start / Distance travelled
|
HOM
|
32f:32m
|
|
|
NotProcessed |
Hspb3tm1.1(KOMP)Vlcg
|
JAX
|
Combined SHIRPA and Dysmorphology / Vocalization
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Hspb3tm1.1(KOMP)Vlcg
|
JAX
|
Combined SHIRPA and Dysmorphology / Touch escape
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Hspb3tm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP3_S
|
HOM
|
5f:8m
|
|
|
NotProcessed |
Hspb3tm1.1(KOMP)Vlcg
|
JAX
|
Tail Suspension / Time immobile
|
HOM
|
5f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.979
|
Successful |
Hspb3tm1.1(KOMP)Vlcg
|
JAX
|
Sleep Wake / Sleep daily percent
|
HOM
|
8f:7m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.0433
|
Successful |
Hspb3tm1.1(KOMP)Vlcg
|
JAX
|
Light-Dark Test / Dark side time spent
|
HOM
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.454
|
Successful |
Hspb3tm1.1(KOMP)Vlcg
|
JAX
|
Grip Strength / Forelimb and hindlimb grip strength measurement mean
|
HOM
|
1f:3m
|
|
|
NotProcessed |
Hspb3tm1.1(KOMP)Vlcg
|
JAX
|
Grip Strength / Forelimb and hindlimb grip strength measurement mean
|
HOM
|
6f:4m
|
Linear Mixed Model framework, LME, including Weight
|
0.0905
|
Successful |
Hspb3tm1.1(KOMP)Vlcg
|
JAX
|
Sleep Wake / Sleep light phase percent
|
HOM
|
8f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.604
|
Successful |
Hspb3tm1.1(KOMP)Vlcg
|
JAX
|
Open Field - centre start / Number of rears - total
|
HOM
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0136
|
Successful |
Hspb3tm1.1(KOMP)Vlcg
|
JAX
|
Grip Strength / Forelimb grip strength measurement
|
HOM
|
3f:9m
|
|
|
NotProcessed |
Hspb3tm1.1(KOMP)Vlcg
|
JAX
|
Grip Strength / Forelimb grip strength measurement
|
HOM
|
18f:12m
|
|
|
NotProcessed |
Hspb3tm1.1(KOMP)Vlcg
|
JAX
|
Rotarod / Latency to fall
|
HOM
|
40f:40m
|
|
|
NotProcessed |
Hspb3tm1.1(KOMP)Vlcg
|
JAX
|
Sleep Wake / Peak wake with respect to dark onset median
|
HOM
|
8f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.397
|
Successful |
Hspb3tm1.1(KOMP)Vlcg
|
JAX
|
Tail Suspension / Latency to immobility
|
HOM
|
5f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.831
|
Successful |
Hspb3tm1.1(KOMP)Vlcg
|
JAX
|
Grip Strength / Forelimb grip strength normalised against body weight
|
HOM
|
1f:3m
|
|
|
NotProcessed |
Hspb3tm1.1(KOMP)Vlcg
|
JAX
|
Grip Strength / Forelimb grip strength normalised against body weight
|
HOM
|
6f:4m
|
Linear Mixed Model framework, LME, not including Weight
|
0.467
|
Successful |
Hspb3tm1.1(KOMP)Vlcg
|
JAX
|
Combined SHIRPA and Dysmorphology / Locomotor activity
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.271
|
Successful |
Hspb3tm1.1(KOMP)Vlcg
|
JAX
|
Eye Morphology / Optic Disc
|
HOM
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Hspb3tm1.1(KOMP)Vlcg
|
JAX
|
Combined SHIRPA and Dysmorphology / Tail elevation
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Hspb3tm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP2_S
|
HOM
|
5f:8m
|
|
|
NotProcessed |
Hspb3tm1.1(KOMP)Vlcg
|
JAX
|
Open Field - centre start / Periphery average speed
|
HOM
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.232
|
Successful |
Hspb3tm1.1(KOMP)Vlcg
|
JAX
|
Light-Dark Test / Time mobile dark side
|
HOM
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.641
|
Successful |
Hspb3tm1.1(KOMP)Vlcg
|
JAX
|
Light-Dark Test / Fecal boli
|
HOM
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0218
|
Successful |
Hspb3tm1.1(KOMP)Vlcg
|
JAX
|
Combined SHIRPA and Dysmorphology / Contact righting
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Hspb3tm1.1(KOMP)Vlcg
|
JAX
|
Sleep Wake / Sleep dark phase percent
|
HOM
|
8f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0487
|
Successful |
Hspb3tm1.1(KOMP)Vlcg
|
JAX
|
Grip Strength / Forelimb and hindlimb grip strength normalised against body weight
|
HOM
|
1f:3m
|
|
|
NotProcessed |
Hspb3tm1.1(KOMP)Vlcg
|
JAX
|
Grip Strength / Forelimb and hindlimb grip strength normalised against body weight
|
HOM
|
6f:4m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0103
|
Successful |
Hspb3tm1.1(KOMP)Vlcg
|
JAX
|
Grip Strength / Forelimb and hindlimb grip strength measurement
|
HOM
|
3f:9m
|
|
|
NotProcessed |
Hspb3tm1.1(KOMP)Vlcg
|
JAX
|
Grip Strength / Forelimb and hindlimb grip strength measurement
|
HOM
|
18f:12m
|
|
|
NotProcessed |
Hspb3tm1.1(KOMP)Vlcg
|
JAX
|
Open Field - centre start / Distance travelled - total
|
HOM
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0936
|
Successful |
Hspb3tm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP1_S
|
HOM
|
5f:8m
|
|
|
NotProcessed |
Hspb3tm1.1(KOMP)Vlcg
|
JAX
|
Sleep Wake / Breath rate during sleep mean
|
HOM
|
8f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.571
|
Successful |
Hspb3tm1.1(KOMP)Vlcg
|
JAX
|
Open Field - centre start / Periphery permanence time
|
HOM
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.606
|
Successful |
Hspb3tm1.1(KOMP)Vlcg
|
JAX
|
Combined SHIRPA and Dysmorphology / Gait
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Hspb3tm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI1
|
HOM
|
5f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0215
|
Successful |
Hspb3tm1.1(KOMP)Vlcg
|
JAX
|
Rotarod / Learning slope
|
HOM
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0375
|
Successful |
Hspb3tm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP4
|
HOM
|
2f:4m
|
|
|
NotProcessed |
Hspb3tm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI3
|
HOM
|
5f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.823
|
Successful |
Hspb3tm1.1(KOMP)Vlcg
|
JAX
|
Sleep Wake / Sleep bout lengths mean
|
HOM
|
8f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.154
|
Successful |
Hspb3tm1.1(KOMP)Vlcg
|
JAX
|
Combined SHIRPA and Dysmorphology / Tremor
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Hspb3tm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI2
|
HOM
|
5f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.108
|
Successful |
Hspb3tm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - S
|
HOM
|
5f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.104
|
Successful |
Hspb3tm1.1(KOMP)Vlcg
|
JAX
|
Light-Dark Test / Latency to first transition into dark
|
HOM
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.725
|
Successful |
Hspb3tm1.1(KOMP)Vlcg
|
JAX
|
Rotarod / Learning difference
|
HOM
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0348
|
Successful |
Hspb3tm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI4
|
HOM
|
2f:4m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.278
|
Successful |
Hspb3tm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP3
|
HOM
|
5f:8m
|
|
|
NotProcessed |
Hspb3tm1.1(KOMP)Vlcg
|
JAX
|
Sleep Wake / Dark sleep bout lengths standard deviation
|
HOM
|
8f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.245
|
Successful |
Hspb3tm1.1(KOMP)Vlcg
|
JAX
|
Combined SHIRPA and Dysmorphology / Limb grasp
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
0.382
|
Successful |
Hspb3tm1.1(KOMP)Vlcg
|
JAX
|
Eye Morphology / Pupil Light Response
|
HOM
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Hspb3tm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP4_S
|
HOM
|
2f:4m
|
|
|
NotProcessed |
Hspb3tm1.1(KOMP)Vlcg
|
JAX
|
Sleep Wake / Light sleep bout lengths mean
|
HOM
|
8f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.855
|
Successful |
Hspb3tm1.1(KOMP)Vlcg
|
JAX
|
Combined SHIRPA and Dysmorphology / Transfer arousal
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Hspb3tm1.1(KOMP)Vlcg
|
JAX
|
Sleep Wake / Sleep bout lengths standard deviation
|
HOM
|
8f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.389
|
Successful |
Hspb3tm1.1(KOMP)Vlcg
|
JAX
|
Light-Dark Test / Percent time in dark
|
HOM
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0537
|
Successful |
Hspb3tm1.1(KOMP)Vlcg
|
JAX
|
Sleep Wake / Activity onset with respect to dark onset median
|
HOM
|
8f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.293
|
Successful |
Hspb3tm1.1(KOMP)Vlcg
|
JAX
|
Rotarod / Average duration
|
HOM
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.917
|
Successful |
Hspb3tm1.1(KOMP)Vlcg
|
JAX
|
Open Field - centre start / Center distance travelled
|
HOM
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.00149
|
Successful |