Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Combined SHIRPA and Dysmorphology / Tail - thickness
|
HOM
|
8f:9m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Forepaw footpad size
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Combined SHIRPA and Dysmorphology / Coat - hair distribution - back
|
HOM
|
8f:9m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Eye Morphology / Bulging eye
|
HOM
|
8f:9m
|
|
|
NotProcessed |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Eye Morphology / Bulging eye
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / External genitalia morphology
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Eye Morphology / Iris/Pupil
|
HOM
|
8f:9m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Eye Morphology / Iris/Pupil
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Adult LacZ / Cartilage tissue
|
HET
|
1f:1m
|
|
|
NotProcessed |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Snout morphology
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Adult LacZ / Striatum
|
HET
|
1f:1m
|
|
|
NotProcessed |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Hematology / Mean cell hemoglobin concentration
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.586
|
Successful |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Hematology / Mean cell hemoglobin concentration
|
HOM
|
8f:9m
|
Linear Mixed Model framework, LME, not including Weight
|
0.825
|
Successful |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
DSS Histology / Comment
|
HOM
|
f:1m
|
|
|
NotProcessed |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
X-ray / Kyphosis
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP2
|
HOM
|
6f:6m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Indirect Calorimetry / Body weight before experiment
|
HOM
|
8f:9m
|
|
|
NotProcessed |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Indirect Calorimetry / Body weight before experiment
|
HOM
|
f:7m
|
|
|
NotProcessed |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
X-ray / Lumbar processes
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Incisors morphology
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Heart Weight / Heart weight normalised against body weight
|
HOM
|
7f:4m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Heart Weight / Heart weight normalised against body weight
|
HOM
|
8f:9m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Eye Morphology / Corneal deposits
|
HOM
|
8f:9m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Indirect Calorimetry / Total food intake
|
HOM
|
8f:9m
|
Linear Mixed Model framework, LME, not including Weight
|
0.693
|
Successful |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Indirect Calorimetry / Total food intake
|
HOM
|
f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.926
|
Successful |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
X-ray / Fibula
|
HOM
|
5f:4m
|
|
|
NotProcessed |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
X-ray / Fibula
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
X-ray / Shape of vertebrae
|
HOM
|
5f:4m
|
|
|
NotProcessed |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
X-ray / Shape of vertebrae
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Auditory Brain Stem Response / 6kHz-evoked ABR Threshold
|
HOM
|
4f:m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Auditory Brain Stem Response / 6kHz-evoked ABR Threshold
|
HOM
|
4f:3m
|
Reference Range Plus Test framework; quantile = 0.95 (Tails probability = 0.025)
|
0.0370
|
Successful |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Adult LacZ / Diaphragm
|
HET
|
1f:1m
|
|
|
NotProcessed |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Trunk curl
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Body Composition (DEXA lean/fat) / Body length
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.0633
|
Successful |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Cortical Bone MicroCT / Cortical Bone Mineral Density
|
HOM
|
2f:m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Adult LacZ / Peyers Patch
|
HET
|
1f:1m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Adult LacZ / Small Intestine
|
HET
|
1f:1m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Eye Morphology / Lens Opacity
|
HOM
|
8f:9m
|
Fisher Exact Test framework
|
0.00258
|
Successful |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Eye Morphology / Lens Opacity
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Limb skin appearance
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Antigen Specific Immunoglobulin Assay / Comment
|
HOM
|
f:m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Combined SHIRPA and Dysmorphology / Skin texture - back paws
|
HOM
|
8f:9m
|
|
|
NotProcessed |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Clinical Chemistry / LDL-cholesterol
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.979
|
Successful |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Combined SHIRPA and Dysmorphology / Forelimbs - shape
|
HOM
|
8f:9m
|
|
|
NotProcessed |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Vertebral Microradiography / Vertebral Height
|
HOM
|
2f:m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Open Field / Periphery distance travelled
|
HOM
|
8f:9m
|
Linear Mixed Model framework, LME, including Weight
|
0.630
|
Successful |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Hindlimb size
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Buffy coat peripheral blood leukocyte immunophenotyping / CD8+CD44+CD62L- percentage
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Adult LacZ / Lymph Node
|
HET
|
1f:1m
|
|
|
NotProcessed |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Forepaw morphology
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
X-ray / Zygomatic bone
|
HOM
|
5f:4m
|
|
|
NotProcessed |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
X-ray / Zygomatic bone
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Head skin colour
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Head coat/hair length
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Clinical Chemistry / Calcium
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.319
|
Successful |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Clinical Chemistry / Calcium
|
HOM
|
8f:9m
|
Linear Mixed Model framework, LME, not including Weight
|
0.990
|
Successful |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Echo / HR
|
HOM
|
8f:9m
|
Linear Mixed Model framework, LME, including Weight
|
0.517
|
Successful |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Ventral coat/hair colour pattern
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Limb coat/hair length
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Open Field / Percentage center movement time
|
HOM
|
8f:9m
|
Linear Mixed Model framework, LME, not including Weight
|
0.445
|
Successful |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
X-ray / Shape of ribs
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
X-ray / Shape of ribs
|
HOM
|
5f:4m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Combined SHIRPA and Dysmorphology / Tail elevation
|
HOM
|
4f:6m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Electrocardiogram (ECG) / Number of signals
|
HOM
|
8f:9m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Combined SHIRPA and Dysmorphology / Skin color - ear
|
HOM
|
8f:9m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Combined SHIRPA and Dysmorphology / Hindlimb nail - number
|
HOM
|
8f:9m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Grip Strength / Forelimb and hindlimb grip strength normalised against body weight
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
3.33×10-05
|
Successful |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Grip Strength / Forelimb and hindlimb grip strength normalised against body weight
|
HOM
|
4f:6m
|
Linear Mixed Model framework, LME, not including Weight
|
0.207
|
Successful |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Grip Strength / Body weight
|
HOM
|
4f:6m
|
|
|
NotProcessed |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Grip Strength / Body weight
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Intraperitoneal glucose tolerance test (IPGTT) / Area under glucose response curve
|
HOM
|
7f:6m
|
Linear Mixed Model framework, LME, not including Weight
|
0.263
|
Successful |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Intraperitoneal glucose tolerance test (IPGTT) / Area under glucose response curve
|
HOM
|
8f:9m
|
Linear Mixed Model framework, LME, not including Weight
|
0.492
|
Successful |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Tail length
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Eye Morphology / Mean left eye lens density
|
HOM
|
8f:9m
|
Linear Mixed Model framework, LME, not including Weight
|
0.000171
|
Successful |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI3
|
HOM
|
6f:6m
|
Linear Mixed Model framework, LME, including Weight
|
0.00909
|
Successful |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Clinical Chemistry / Potassium
|
HOM
|
8f:9m
|
Linear Mixed Model framework, LME, not including Weight
|
0.365
|
Successful |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Clinical Chemistry / Potassium
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.548
|
Successful |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Auditory Brain Stem Response / 30kHz-evoked ABR Threshold
|
HOM
|
4f:m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Auditory Brain Stem Response / 30kHz-evoked ABR Threshold
|
HOM
|
3f:2m
|
Reference Range Plus Test framework; quantile = 0.95 (Tails probability = 0.025)
|
0.0315
|
Successful |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Clinical Chemistry / Phosphorus
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.0861
|
Successful |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Clinical Chemistry / Phosphorus
|
HOM
|
8f:9m
|
Linear Mixed Model framework, LME, not including Weight
|
0.494
|
Successful |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Combined SHIRPA and Dysmorphology / Hindpaw - shape
|
HOM
|
8f:9m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Combined SHIRPA and Dysmorphology / Genitalia - morphology
|
HOM
|
8f:9m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Viability Primary Screen / Viability Outcome
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Viability Primary Screen / Viability Outcome
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Salmonella Challenge / Spleen Dilution Reading
|
HOM
|
2f:2m
|
|
|
NotProcessed |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Head bobbing/circling
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Combined SHIRPA and Dysmorphology / Head morphology
|
HOM
|
8f:9m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Forepaw nail colour
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Electrocardiogram (ECG) / ST
|
HOM
|
8f:9m
|
Linear Mixed Model framework, LME, including Weight
|
0.0911
|
Successful |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Indirect Calorimetry / Respiratory Exchange Ratio
|
HOM
|
8f:9m
|
Linear Mixed Model framework, LME, including Weight
|
0.422
|
Successful |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Indirect Calorimetry / Respiratory Exchange Ratio
|
HOM
|
f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.767
|
Successful |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Digit coat/hair colour pattern
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Eye Morphology / Corneal vascularization
|
HOM
|
8f:9m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Eye Morphology / Corneal vascularization
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Adult LacZ / Chest bone
|
HET
|
1f:1m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Eye Morphology / Retinal Blood Vessels Pattern
|
HOM
|
8f:9m
|
Fisher Exact Test framework
|
3.32×10-05
|
Successful |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Eye Morphology / Retinal Blood Vessels Pattern
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Clinical Chemistry / Triglycerides
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.116
|
Successful |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Clinical Chemistry / Triglycerides
|
HOM
|
7f:9m
|
Linear Mixed Model framework, LME, including Weight
|
2.53×10-05
|
Successful |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Head size
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Hematology / Platelet count
|
HOM
|
8f:9m
|
Linear Mixed Model framework, LME, including Weight
|
0.166
|
Successful |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Hematology / Platelet count
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.228
|
Successful |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / External genitalia
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP1
|
HOM
|
6f:6m
|
|
|
NotProcessed |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Hindlimb morphology
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Indirect Calorimetry / Cumulative food intake
|
HOM
|
f:155m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Adult LacZ / Thymus
|
HET
|
1f:1m
|
|
|
NotProcessed |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Transfer arousal
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
0.0174
|
Successful |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Adult LacZ / Skeletal Muscle
|
HET
|
1f:1m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Eye Morphology / Pupil Position
|
HOM
|
8f:9m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Eye Morphology / Pupil Position
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Combined SHIRPA and Dysmorphology / Hindlimbs - position
|
HOM
|
8f:9m
|
|
|
NotProcessed |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Limb skin colour
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Adult LacZ / Peripheral Nervous System
|
HET
|
1f:1m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Open Field / Latency to center entry
|
HOM
|
8f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.679
|
Successful |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
X-ray / Scoliosis
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Incisor colour
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Adult LacZ / Vesicular Gland
|
HET
|
1f:1m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Combined SHIRPA and Dysmorphology / Forelimbs - size
|
HOM
|
8f:9m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Electrocardiogram (ECG) / pNN5(6>ms)
|
HOM
|
8f:9m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Adult LacZ / Mammary gland
|
HET
|
1f:1m
|
|
|
NotProcessed |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
X-ray / Fusion of vertebrae
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
X-ray / Fusion of vertebrae
|
HOM
|
5f:4m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
X-ray / Tibia
|
HOM
|
5f:4m
|
|
|
NotProcessed |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
X-ray / Tibia
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Combined SHIRPA and Dysmorphology / Tail - morphology
|
HOM
|
8f:9m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Combined SHIRPA and Dysmorphology / Coat - color pattern - abdomen
|
HOM
|
8f:9m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Eye Morphology / Iris transilumination
|
HOM
|
8f:9m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Combined SHIRPA and Dysmorphology / Touch escape
|
HOM
|
4f:6m
|
|
|
NotProcessed |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Head skin appearance
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Grip Strength / Forelimb and hindlimb grip strength measurement mean
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
7.79×10-06
|
Successful |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Grip Strength / Forelimb and hindlimb grip strength measurement mean
|
HOM
|
4f:6m
|
Linear Mixed Model framework, LME, including Weight
|
0.275
|
Successful |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Paw footpad skin appearance
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Salmonella Challenge / Caecal Contents Dilution Reading
|
HOM
|
2f:2m
|
|
|
NotProcessed |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Digit coat/hair appearance
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Adult LacZ / Adrenal gland
|
HET
|
1f:1m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Electrocardiogram (ECG) / QTc
|
HOM
|
8f:9m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Eye Morphology / Lens
|
HOM
|
8f:9m
|
Fisher Exact Test framework
|
0.00380
|
Successful |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Eye Morphology / Lens
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Grip Strength / Forelimb grip strength normalised against body weight
|
HOM
|
4f:6m
|
Linear Mixed Model framework, LME, not including Weight
|
0.359
|
Successful |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Grip Strength / Forelimb grip strength normalised against body weight
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.801
|
Successful |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Combined SHIRPA and Dysmorphology / Head size
|
HOM
|
8f:9m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Tail morphology
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Open Field / Center average speed
|
HOM
|
8f:9m
|
Linear Mixed Model framework, LME, not including Weight
|
0.230
|
Successful |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Clinical Chemistry / Sodium
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.0266
|
Successful |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Clinical Chemistry / Sodium
|
HOM
|
8f:9m
|
Linear Mixed Model framework, LME, including Weight
|
0.824
|
Successful |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Combined SHIRPA and Dysmorphology / Forepaw - shape
|
HOM
|
8f:9m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Adult LacZ / Blood
|
HET
|
1f:1m
|
|
|
NotProcessed |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Femoral Microradiography / Femur Length
|
HOM
|
2f:m
|
|
|
NotProcessed |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Buffy coat peripheral blood leukocyte immunophenotyping / T cell CD3+ percentage
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Rotarod / Latency to fall
|
HOM
|
f:9m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
X-ray / Alive
|
HOM
|
5f:4m
|
|
|
NotProcessed |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
X-ray / Alive
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Ventral coat/hair colour
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Adult LacZ / Vagina
|
HET
|
1f:1m
|
|
|
NotProcessed |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Body Composition (DEXA lean/fat) / Bone Mineral Content (excluding skull)
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.0121
|
Successful |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Corneal touch reflex
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Contact righting reflex
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Combined SHIRPA and Dysmorphology / Skin color - snout
|
HOM
|
8f:9m
|
|
|
NotProcessed |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Forepaw nail morphology
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Adult LacZ / Trachea
|
HET
|
1f:1m
|
|
|
NotProcessed |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Buffy coat peripheral blood leukocyte immunophenotyping / Comment
|
HOM
|
f:m
|
|
|
NotProcessed |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Clinical Chemistry / HDL-cholesterol
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.275
|
Successful |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Clinical Chemistry / HDL-cholesterol
|
HOM
|
7f:9m
|
Linear Mixed Model framework, LME, including Weight
|
0.915
|
Successful |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Eye Morphology / Persistence of hyaloid vascular system
|
HOM
|
8f:9m
|
Fisher Exact Test framework
|
0.536
|
Successful |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Eye Morphology / Persistence of hyaloid vascular system
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI2
|
HOM
|
6f:6m
|
Linear Mixed Model framework, LME, including Weight
|
0.0492
|
Successful |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Adult LacZ / Cerebral Cortex
|
HET
|
1f:1m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Eye Morphology / Eye
|
HOM
|
8f:9m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
X-ray / Processes on vertebrae
|
HOM
|
5f:4m
|
|
|
NotProcessed |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Vertebra Compression / Vertebra Yield Load
|
HOM
|
2f:m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
X-ray / Maxilla/Pre-maxilla
|
HOM
|
5f:4m
|
|
|
NotProcessed |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
X-ray / Maxilla/Pre-maxilla
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Combined SHIRPA and Dysmorphology / Mouth morphology
|
HOM
|
8f:9m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Adult LacZ / Testis
|
HET
|
1f:1m
|
|
|
NotProcessed |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Gait (inc. ataxia)
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Tail coat/hair appearance
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Adult LacZ / Kidney
|
HET
|
1f:1m
|
|
|
NotProcessed |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
X-ray / Caudal processes
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Adult LacZ / Harderian Gland
|
HET
|
1f:1m
|
|
|
NotProcessed |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Ventral skin appearance
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Combined SHIRPA and Dysmorphology / Head bobbing
|
HOM
|
4f:6m
|
|
|
NotProcessed |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Hindlimb
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Adult LacZ / Sciatic nerve
|
HET
|
1f:1m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Heart Weight / Tibia length
|
HOM
|
8f:9m
|
Linear Mixed Model framework, LME, including Weight
|
0.167
|
Successful |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Head morphology
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Adult LacZ / Pituitary gland
|
HET
|
1f:1m
|
|
|
NotProcessed |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Dorsal coat/hair colour
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
X-ray / Number of ribs right
|
HOM
|
5f:4m
|
|
|
NotProcessed |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
X-ray / Number of ribs right
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Eye Morphology / Max left eye lens density
|
HOM
|
8f:9m
|
Linear Mixed Model framework, LME, including Weight
|
0.474
|
Successful |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Electrocardiogram (ECG) / rMSSD
|
HOM
|
8f:9m
|
Linear Mixed Model framework, LME, including Weight
|
0.582
|
Successful |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Eye Morphology / Retina
|
HOM
|
8f:9m
|
|
|
NotProcessed |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Eye Morphology / Retina
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Combined SHIRPA and Dysmorphology / Skin texture - ear
|
HOM
|
8f:9m
|
|
|
NotProcessed |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Body Composition (DEXA lean/fat) / Body weight
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Body Composition (DEXA lean/fat) / Body weight
|
HOM
|
8f:8m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Electrocardiogram (ECG) / PR
|
HOM
|
8f:9m
|
Linear Mixed Model framework, LME, not including Weight
|
0.372
|
Successful |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Clinical Chemistry / Alpha-amylase
|
HOM
|
8f:9m
|
Linear Mixed Model framework, LME, including Weight
|
0.847
|
Successful |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Clinical Chemistry / Alpha-amylase
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.969
|
Successful |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Clinical Chemistry / Iron
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.0236
|
Successful |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Clinical Chemistry / Iron
|
HOM
|
8f:9m
|
Linear Mixed Model framework, LME, not including Weight
|
0.720
|
Successful |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Clinical Chemistry / Magnesium
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.107
|
Successful |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Convulsions
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Combined SHIRPA and Dysmorphology / Genitalia - size
|
HOM
|
8f:9m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Open Field / Periphery permanence time
|
HOM
|
8f:9m
|
Linear Mixed Model framework, LME, not including Weight
|
0.375
|
Successful |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Combined SHIRPA and Dysmorphology / Forelimb nail - length
|
HOM
|
8f:9m
|
|
|
NotProcessed |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Forepaw digit size
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Adult LacZ / Urinary bladder
|
HET
|
1f:1m
|
|
|
NotProcessed |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Salmonella Challenge / Pre-Day 14 Death
|
HOM
|
2f:2m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Combined SHIRPA and Dysmorphology / Aggression
|
HOM
|
4f:6m
|
Fisher Exact Test framework
|
0.0827
|
Successful |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Hindpaw digit fusion
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Open Field / Number of center entries
|
HOM
|
8f:9m
|
Linear Mixed Model framework, LME, not including Weight
|
0.868
|
Successful |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Tail
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Combined SHIRPA and Dysmorphology / Startle response
|
HOM
|
4f:6m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Adult LacZ / Olfactory Lobe
|
HET
|
1f:1m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Combined SHIRPA and Dysmorphology / Hindlimbs - shape
|
HOM
|
8f:9m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Grip Strength / Forelimb grip strength measurement mean
|
HOM
|
4f:6m
|
Linear Mixed Model framework, LME, including Weight
|
0.371
|
Successful |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Grip Strength / Forelimb grip strength measurement mean
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.968
|
Successful |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Ventral coat/hair appearance
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - BN
|
HOM
|
6f:6m
|
|
|
NotProcessed |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Three-point Bend / Energy Dissipated Prior to Fracture
|
HOM
|
2f:m
|
|
|
NotProcessed |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
DSS Histology / Pre-Day 10 Death
|
HOM
|
2f:2m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Echo / LVPWs
|
HOM
|
8f:9m
|
Linear Mixed Model framework, LME, including Weight
|
0.924
|
Successful |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Limb coat/hair appearance
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Electrocardiogram (ECG) / QT Dispersion
|
HOM
|
8f:9m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0539
|
Successful |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
DSS Histology / Total section 1 score
|
HOM
|
2f:2m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
X-ray / Femur
|
HOM
|
5f:4m
|
|
|
NotProcessed |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
X-ray / Femur
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Pinna
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Clinical Chemistry / Free fatty acids
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.164
|
Successful |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Eye Morphology / Cornea
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
0.343
|
Successful |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Eye Morphology / Cornea
|
HOM
|
8f:9m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Auditory Brain Stem Response / 12kHz-evoked ABR Threshold
|
HOM
|
4f:m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Auditory Brain Stem Response / 12kHz-evoked ABR Threshold
|
HOM
|
4f:3m
|
Reference Range Plus Test framework; quantile = 0.95 (Tails probability = 0.025)
|
0.0255
|
Successful |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Eye Morphology / Max right eye lens density
|
HOM
|
8f:9m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0562
|
Successful |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Body Composition (DEXA lean/fat) / Bone Mineral Density (excluding skull)
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.273
|
Successful |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Pinna position
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Echo / Ejection Fraction
|
HOM
|
8f:9m
|
Linear Mixed Model framework, LME, including Weight
|
0.154
|
Successful |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Hematology / Red blood cell count
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0110
|
Successful |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Hematology / Red blood cell count
|
HOM
|
8f:9m
|
Linear Mixed Model framework, LME, including Weight
|
0.939
|
Successful |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Paw coat/hair colour
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Clinical Chemistry / LIH (Hemolysis Severity - available on AU analysers)
|
HOM
|
8f:9m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Adult LacZ / Trigeminal V nerve
|
HET
|
1f:1m
|
|
|
NotProcessed |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Hindpaw digit count
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Combined SHIRPA and Dysmorphology / Skin texture - tail
|
HOM
|
8f:9m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Buffy coat peripheral blood leukocyte immunophenotyping / Mature B cell IgD+ percentage
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Combined SHIRPA and Dysmorphology / Vibrissae - appearance
|
HOM
|
8f:9m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Eye Morphology / Iris Pigmentation
|
HOM
|
8f:9m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Eye Morphology / Iris Pigmentation
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Adult LacZ / Penis
|
HET
|
1f:1m
|
|
|
NotProcessed |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Paw footpad skin colour
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Buffy coat peripheral blood leukocyte immunophenotyping / T cell CD4+ percentage
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Salmonella Challenge / Liver Weight
|
HOM
|
2f:2m
|
|
|
NotProcessed |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Startle response
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
0.193
|
Successful |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
X-ray / Thoracic processes
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
X-ray / Humerus
|
HOM
|
5f:4m
|
|
|
NotProcessed |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
X-ray / Humerus
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Combined SHIRPA and Dysmorphology / Limb grasp
|
HOM
|
4f:6m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Rotarod / Latency to fall_Mean
|
HOM
|
f:3m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Adult LacZ / Cerebellum
|
HET
|
1f:1m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Combined SHIRPA and Dysmorphology / Coat - color pattern - head
|
HOM
|
8f:9m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Clinical Chemistry / Urea (Blood Urea Nitrogen - BUN)
|
HOM
|
8f:9m
|
Linear Mixed Model framework, LME, not including Weight
|
0.334
|
Successful |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Clinical Chemistry / Urea (Blood Urea Nitrogen - BUN)
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.720
|
Successful |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Electrocardiogram (ECG) / Mean R amplitude
|
HOM
|
8f:9m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Combined SHIRPA and Dysmorphology / Genitalia - presence
|
HOM
|
8f:9m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Open Field / Periphery resting time
|
HOM
|
8f:9m
|
Linear Mixed Model framework, LME, including Weight
|
0.896
|
Successful |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
X-ray / Number of lumbar vertebrae
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
X-ray / Number of lumbar vertebrae
|
HOM
|
5f:4m
|
|
|
NotProcessed |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
X-ray / Lordosis
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Ventral skin colour
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
X-ray / Ulna
|
HOM
|
5f:4m
|
|
|
NotProcessed |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
X-ray / Ulna
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
X-ray / Sacral processes
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Tail coat/hair length
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Rotarod / Body weight
|
HOM
|
f:3m
|
|
|
NotProcessed |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Forepaw digit count
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Combined SHIRPA and Dysmorphology / Hindlimb digit - number
|
HOM
|
8f:9m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Combined SHIRPA and Dysmorphology / Tail - length
|
HOM
|
8f:9m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Digit coat/hair presence
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Indirect Calorimetry / Body weight after experiment
|
HOM
|
f:7m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Indirect Calorimetry / Body weight after experiment
|
HOM
|
8f:9m
|
|
|
NotProcessed |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / External genitalia size
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
X-ray / Number of caudal vertebrae
|
HOM
|
5f:4m
|
|
|
NotProcessed |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
X-ray / Number of caudal vertebrae
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Salmonella Challenge / Liver Counts in 20 micro litres
|
HOM
|
2f:2m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Combined SHIRPA and Dysmorphology / Unexpected behaviors
|
HOM
|
4f:6m
|
Fisher Exact Test framework
|
0.0422
|
Successful |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - Global
|
HOM
|
6f:6m
|
Linear Mixed Model framework, LME, including Weight
|
0.0417
|
Successful |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
X-ray / Number of ribs left
|
HOM
|
5f:4m
|
|
|
NotProcessed |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
X-ray / Number of ribs left
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Open Field / Distance travelled
|
HOM
|
32f:36m
|
|
|
NotProcessed |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Hindpaw nail colour
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Ventral coat/hair length
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Combined SHIRPA and Dysmorphology / Hindlimbs - size
|
HOM
|
8f:9m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Combined SHIRPA and Dysmorphology / Skin texture - front paws
|
HOM
|
8f:9m
|
|
|
NotProcessed |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Body Composition (DEXA lean/fat) / Bone Area
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.0262
|
Successful |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Adult LacZ / Vascular System
|
HET
|
1f:1m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Clinical Chemistry / UIBC (unsaturated iron binding capacity)
|
HOM
|
8f:9m
|
Linear Mixed Model framework, LME, including Weight
|
0.459
|
Successful |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Electrocardiogram (ECG) / QT
|
HOM
|
8f:9m
|
Linear Mixed Model framework, LME, including Weight
|
0.225
|
Successful |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Echo / LVIDs
|
HOM
|
8f:9m
|
Linear Model Using Generalized Least Squares framework, GLS, including Weight
|
0.172
|
Successful |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Echo / Cardiac Output
|
HOM
|
8f:9m
|
Linear Mixed Model framework, LME, including Weight
|
0.985
|
Successful |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Eye Morphology / Retinal Pigmentation
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Eye Morphology / Retinal Pigmentation
|
HOM
|
8f:9m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Adult LacZ / Gall Bladder
|
HET
|
1f:1m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Adult LacZ / Liver
|
HET
|
1f:1m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Adult LacZ / Stomach
|
HET
|
1f:1m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Combined SHIRPA and Dysmorphology / Forelimbs - position
|
HOM
|
8f:9m
|
|
|
NotProcessed |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Hindpaw digit morphology
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Salmonella Challenge / Comment
|
HOM
|
f:m
|
|
|
NotProcessed |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Tail skin colour
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Dorsal coat/hair presence
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP3_S
|
HOM
|
6f:6m
|
|
|
NotProcessed |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Paw coat/hair presence
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Pinna morphology
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Hindpaw digit size
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Combined SHIRPA and Dysmorphology / Skin color - front paws
|
HOM
|
8f:9m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Combined SHIRPA and Dysmorphology / Coat - hair texture / appearance - abdomen
|
HOM
|
8f:9m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
DSS Histology / Section 2 Severe Markers
|
HOM
|
2f:1m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP2_S
|
HOM
|
6f:6m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Adult LacZ / Hippocampus
|
HET
|
1f:1m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Clinical Chemistry / Glucose
|
HOM
|
8f:9m
|
Linear Mixed Model framework, LME, not including Weight
|
0.523
|
Successful |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Clinical Chemistry / Glucose
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.609
|
Successful |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Fertility of Homozygous Knock-out Mice / Gross Findings Female
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
X-ray / Skull shape
|
HOM
|
5f:4m
|
|
|
NotProcessed |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
X-ray / Skull shape
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Echo / Fractional Shortening
|
HOM
|
8f:9m
|
Linear Mixed Model framework, LME, including Weight
|
0.146
|
Successful |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Combined SHIRPA and Dysmorphology / Forelimb nail - number
|
HOM
|
8f:9m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Adult LacZ / Spinal cord
|
HET
|
1f:1m
|
|
|
NotProcessed |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Indirect Calorimetry / Oxygen consumption
|
HOM
|
f:155m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Indirect Calorimetry / Oxygen consumption
|
HOM
|
672f:756m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Electrocardiogram (ECG) / QRS
|
HOM
|
8f:9m
|
Linear Mixed Model framework, LME, not including Weight
|
0.145
|
Successful |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Forelimb
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Adult LacZ / Stomach pyloric region
|
HET
|
1f:1m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Rotarod / Passive rotation
|
HOM
|
f:9m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Combined SHIRPA and Dysmorphology / Forelimb digit - number
|
HOM
|
8f:9m
|
|
|
NotProcessed |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Digit coat/hair colour
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Combined SHIRPA and Dysmorphology / Tail - presence
|
HOM
|
8f:9m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Insulin Blood Level / Insulin
|
HOM
|
f:2m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Insulin Blood Level / Insulin
|
HOM
|
4f:3m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.596
|
Successful |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Insulin Blood Level / Insulin
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.689
|
Successful |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Insulin Blood Level / Insulin
|
HOM
|
3f:4m
|
Linear Mixed Model framework, LME, including Weight
|
0.977
|
Successful |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Clinical Chemistry / Chloride
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.270
|
Successful |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Clinical Chemistry / Chloride
|
HOM
|
8f:9m
|
Linear Mixed Model framework, LME, including Weight
|
0.500
|
Successful |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI4
|
HOM
|
6f:6m
|
Linear Mixed Model framework, LME, including Weight
|
0.397
|
Successful |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Body Composition (DEXA lean/fat) / Lean mass
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.218
|
Successful |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Body Composition (DEXA lean/fat) / Lean mass
|
HOM
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.790
|
Successful |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Eye Morphology / Pupil Light Response
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Eye Morphology / Pupil Light Response
|
HOM
|
8f:9m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Eye Morphology / Min right eye lens density
|
HOM
|
8f:9m
|
Linear Mixed Model framework, LME, including Weight
|
0.00186
|
Successful |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Eye Morphology / Corneal opacity
|
HOM
|
8f:9m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Eye Morphology / Corneal opacity
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Buffy coat peripheral blood leukocyte immunophenotyping / Treg cell CD25+ percentage
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Adult LacZ / Prostate gland
|
HET
|
1f:1m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
X-ray / Number of pelvic vertebrae
|
HOM
|
5f:4m
|
|
|
NotProcessed |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
X-ray / Number of pelvic vertebrae
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
X-ray / Shape of ribcage
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
0.234
|
Successful |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Tremor
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Hematology / White blood cell count
|
HOM
|
8f:9m
|
Linear Mixed Model framework, LME, not including Weight
|
0.101
|
Successful |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Hematology / White blood cell count
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.339
|
Successful |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Combined SHIRPA and Dysmorphology / Forelimb digit - size
|
HOM
|
8f:9m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Clinical Chemistry / Alanine aminotransferase
|
HOM
|
8f:9m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0720
|
Successful |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Clinical Chemistry / Alanine aminotransferase
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.301
|
Successful |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Eye Morphology / Ophthalmoscope Observation
|
HOM
|
2f:2m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Echo / LVPWd
|
HOM
|
8f:9m
|
Linear Mixed Model framework, LME, including Weight
|
0.656
|
Successful |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Clinical Chemistry / Lipase
|
HOM
|
7f:9m
|
Linear Mixed Model framework, LME, including Weight
|
0.883
|
Successful |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Combined SHIRPA and Dysmorphology / Forelimb nail - shape
|
HOM
|
8f:9m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Electrocardiogram (ECG) / RR
|
HOM
|
8f:9m
|
Linear Mixed Model framework, LME, not including Weight
|
0.808
|
Successful |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Combined SHIRPA and Dysmorphology / Skin texture - whole body
|
HOM
|
8f:9m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Eye Morphology / Scheimpflug description
|
HOM
|
f:3m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Combined SHIRPA and Dysmorphology / Trunk curl
|
HOM
|
4f:6m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Clinical Chemistry / Creatinine
|
HOM
|
8f:9m
|
Linear Mixed Model framework, LME, including Weight
|
0.102
|
Successful |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Clinical Chemistry / Creatinine
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.480
|
Successful |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Dorsal coat/hair appearance
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
X-ray / Number of thoracic vertebrae
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
X-ray / Number of thoracic vertebrae
|
HOM
|
5f:4m
|
|
|
NotProcessed |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Limb coat/hair colour
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Adult LacZ / Sublingual Gland
|
HET
|
1f:1m
|
|
|
NotProcessed |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Trabecular Bone MicroCT / Trabecular Thickness (mm)
|
HOM
|
2f:m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
X-ray / Radius
|
HOM
|
5f:4m
|
|
|
NotProcessed |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
X-ray / Radius
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Tail coat/hair colour
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Hematology / Mean platelet volume
|
HOM
|
8f:9m
|
Linear Mixed Model framework, LME, including Weight
|
0.0451
|
Successful |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Hematology / Mean platelet volume
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.0715
|
Successful |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Open Field / Percentage center time
|
HOM
|
8f:9m
|
Linear Mixed Model framework, LME, not including Weight
|
0.376
|
Successful |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
X-ray / Brachydactyly
|
HOM
|
5f:4m
|
|
|
NotProcessed |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
X-ray / Brachydactyly
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Combined SHIRPA and Dysmorphology / Vibrissae - presence
|
HOM
|
8f:9m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Tail skin appearance
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Combined SHIRPA and Dysmorphology / Lower teeth appearance
|
HOM
|
8f:9m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Hindpaw nail morphology
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
X-ray / Scapulae
|
HOM
|
5f:4m
|
|
|
NotProcessed |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
X-ray / Scapulae
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Buffy coat peripheral blood leukocyte immunophenotyping / Monocyte percentage
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Open Field / Number of Rears
|
HOM
|
32f:36m
|
|
|
NotProcessed |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Head coat/hair presence
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Forepaw digit fusion
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Adult LacZ / Parathyroid gland
|
HET
|
1f:1m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Eye Morphology / Retinal Structure
|
HOM
|
8f:9m
|
|
|
NotProcessed |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Eye Morphology / Retinal Structure
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Adult LacZ / Skin
|
HET
|
1f:1m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Adult LacZ / Esophagus
|
HET
|
1f:1m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Eye Morphology / Retina (combined)
|
HOM
|
8f:9m
|
Fisher Exact Test framework
|
0.000803
|
Successful |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Eye Morphology / Retina (combined)
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
0.266
|
Successful |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Heart Weight / Body weight
|
HOM
|
8f:9m
|
|
|
NotProcessed |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Heart Weight / Body weight
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Adult LacZ / Pancreas
|
HET
|
1f:1m
|
|
|
NotProcessed |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
X-ray / Polysyndactylism
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Pinna size
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Combined SHIRPA and Dysmorphology / Contact righting
|
HOM
|
4f:6m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Hematology / Hematocrit
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.0643
|
Successful |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Hematology / Hematocrit
|
HOM
|
8f:9m
|
Linear Mixed Model framework, LME, not including Weight
|
0.783
|
Successful |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Antigen Specific Immunoglobulin Assay / TetC specific total IgG
|
HOM
|
2f:2m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Combined SHIRPA and Dysmorphology / Coat - hair texture / appearance - head
|
HOM
|
8f:9m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Vibrissae shape
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Clinical Chemistry / Creatine kinase
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.840
|
Successful |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Combined SHIRPA and Dysmorphology / Coat - color - abdomen
|
HOM
|
8f:9m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP1_S
|
HOM
|
6f:6m
|
|
|
NotProcessed |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
DSS Histology / Section 2 Area
|
HOM
|
2f:1m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Adult LacZ / Hypothalamus
|
HET
|
1f:1m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Eye Morphology / Pupil Dilation
|
HOM
|
8f:9m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Eye Morphology / Pupil Dilation
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Body Composition (DEXA lean/fat) / Fat mass
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.117
|
Successful |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Body Composition (DEXA lean/fat) / Fat mass
|
HOM
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.289
|
Successful |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Three-point Bend / Stiffness
|
HOM
|
2f:m
|
|
|
NotProcessed |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Paw coat/hair appearance
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Salmonella Challenge / Liver Dilution Reading
|
HOM
|
2f:2m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Combined SHIRPA and Dysmorphology / Tremor
|
HOM
|
4f:6m
|
Fisher Exact Test framework
|
0.0473
|
Successful |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Clinical Chemistry / Thyroxine
|
HOM
|
5f:1m
|
Linear Mixed Model framework, LME, not including Weight
|
0.492
|
Successful |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Forelimb size
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Indirect Calorimetry / Total water intake
|
HOM
|
f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.126
|
Successful |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Adult LacZ / Vas Deferens
|
HET
|
1f:1m
|
|
|
NotProcessed |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Tail elevation
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Dorsal skin colour
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Combined SHIRPA and Dysmorphology / Upper teeth appearance
|
HOM
|
8f:9m
|
|
|
NotProcessed |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Indirect Calorimetry / Carbon dioxide production
|
HOM
|
f:155m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Indirect Calorimetry / Carbon dioxide production
|
HOM
|
672f:756m
|
|
|
NotProcessed |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Buffy coat peripheral blood leukocyte immunophenotyping / T cell CD8+ percentage
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Intraperitoneal glucose tolerance test (IPGTT) / Body Weight
|
HOM
|
8f:9m
|
|
|
NotProcessed |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Intraperitoneal glucose tolerance test (IPGTT) / Body Weight
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Open Field / Center distance travelled
|
HOM
|
8f:9m
|
Linear Mixed Model framework, LME, not including Weight
|
0.175
|
Successful |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Adult LacZ / Eye
|
HET
|
1f:1m
|
|
|
NotProcessed |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Auditory Brain Stem Response / 18kHz-evoked ABR Threshold
|
HOM
|
4f:m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Auditory Brain Stem Response / 18kHz-evoked ABR Threshold
|
HOM
|
4f:3m
|
Reference Range Plus Test framework; quantile = 0.95 (Tails probability = 0.025)
|
0.0301
|
Successful |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Hindpaw morphology
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Electrocardiogram (ECG) / Mean SR amplitude
|
HOM
|
8f:9m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Adult LacZ / Thyroid gland
|
HET
|
1f:1m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
X-ray / Clavicle
|
HOM
|
5f:4m
|
|
|
NotProcessed |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
X-ray / Clavicle
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Eye Morphology / Right total retinal thickness
|
HOM
|
8f:9m
|
Linear Mixed Model framework, LME, not including Weight
|
0.221
|
Successful |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Body Weight / Body weight curve
|
HOM
|
95f:119m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Body Weight / Body weight curve
|
HOM
|
122f:140m
|
|
|
NotProcessed |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Auditory Brain Stem Response / Body weight
|
HOM
|
4f:m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Auditory Brain Stem Response / Body weight
|
HOM
|
4f:3m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Electrocardiogram (ECG) / PQ
|
HOM
|
8f:9m
|
Linear Mixed Model framework, LME, not including Weight
|
0.695
|
Successful |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Combined SHIRPA and Dysmorphology / Activity (body position)
|
HOM
|
4f:6m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Adult LacZ / Heart
|
HET
|
1f:1m
|
|
|
NotProcessed |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Trabecular Bone MicroCT / Trabecular Spacing (mm)
|
HOM
|
2f:m
|
|
|
NotProcessed |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Buffy coat peripheral blood leukocyte immunophenotyping / NK cell percentage
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Adult LacZ / Epididymis
|
HET
|
1f:1m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Combined SHIRPA and Dysmorphology / Hindlimb digit - size
|
HOM
|
8f:9m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Tail coat/hair colour pattern
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
X-ray / Digit integrity
|
HOM
|
5f:4m
|
|
|
NotProcessed |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
X-ray / Digit integrity
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Adult LacZ / Hindlimb
|
HET
|
1f:1m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Adult LacZ / Cranium
|
HET
|
1f:1m
|
|
|
NotProcessed |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Hindpaw nail length
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Eye Morphology / Slit Lamp observation
|
HOM
|
1f:m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Eye Morphology / Min left eye lens density
|
HOM
|
8f:9m
|
Linear Mixed Model framework, LME, not including Weight
|
0.150
|
Successful |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Combined SHIRPA and Dysmorphology / Skin texture - snout
|
HOM
|
8f:9m
|
|
|
NotProcessed |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Clinical Chemistry / Total protein
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.421
|
Successful |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Clinical Chemistry / Total protein
|
HOM
|
8f:9m
|
Linear Mixed Model framework, LME, not including Weight
|
0.427
|
Successful |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Echo / Respiration Rate
|
HOM
|
8f:9m
|
Linear Mixed Model framework, LME, including Weight
|
0.403
|
Successful |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Body Composition (DEXA lean/fat) / Fat/Body weight
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.149
|
Successful |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Body Composition (DEXA lean/fat) / Fat/Body weight
|
HOM
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.355
|
Successful |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Dorsal coat/hair colour pattern
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
X-ray / Number of cervical vertebrae
|
HOM
|
5f:4m
|
|
|
NotProcessed |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
X-ray / Number of cervical vertebrae
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Eye Morphology / Eyelid closure
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Eye Morphology / Eyelid closure
|
HOM
|
8f:9m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Head coat/hair colour
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Salmonella Challenge / Days post-infection
|
HOM
|
2f:2m
|
|
|
NotProcessed |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Three-point Bend / Fracture Load
|
HOM
|
2f:m
|
|
|
NotProcessed |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Buffy coat peripheral blood leukocyte immunophenotyping / Granulocyte Gr1+ percentage
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Adult LacZ / Oviduct
|
HET
|
1f:1m
|
|
|
NotProcessed |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Limb coat/hair colour pattern
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Echo / LVIDd
|
HOM
|
8f:9m
|
Linear Mixed Model framework, LME, including Weight
|
0.906
|
Successful |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
DSS Histology / Section 1 Epithelium
|
HOM
|
2f:2m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Adult LacZ / Bone
|
HET
|
1f:1m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Combined SHIRPA and Dysmorphology / Hindlimb nail - length
|
HOM
|
8f:9m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Clinical Chemistry / Aspartate aminotransferase
|
HOM
|
8f:9m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0173
|
Successful |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Clinical Chemistry / Aspartate aminotransferase
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.868
|
Successful |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Forepaw digit morphology
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Combined SHIRPA and Dysmorphology / Vocalization
|
HOM
|
4f:6m
|
Fisher Exact Test framework
|
0.408
|
Successful |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Adult LacZ / Cecum
|
HET
|
1f:1m
|
|
|
NotProcessed |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Hematology / Hemoglobin
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.0913
|
Successful |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Hematology / Hemoglobin
|
HOM
|
8f:9m
|
Linear Mixed Model framework, LME, including Weight
|
0.762
|
Successful |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Adult LacZ / Aorta
|
HET
|
1f:1m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
X-ray / Syndactylism
|
HOM
|
5f:4m
|
|
|
NotProcessed |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
X-ray / Syndactylism
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Indirect Calorimetry / Heat production (metabolic rate)
|
HOM
|
672f:756m
|
|
|
NotProcessed |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Indirect Calorimetry / Heat production (metabolic rate)
|
HOM
|
f:155m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Eye Morphology / Mean right eye lens density
|
HOM
|
8f:9m
|
Linear Mixed Model framework, LME, not including Weight
|
3.21×10-06
|
Successful |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Open Field / Whole arena resting time
|
HOM
|
8f:9m
|
Linear Mixed Model framework, LME, including Weight
|
0.682
|
Successful |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Combined SHIRPA and Dysmorphology / Teeth presence
|
HOM
|
8f:9m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Eye Morphology / Vitreous
|
HOM
|
8f:9m
|
Fisher Exact Test framework
|
0.0747
|
Successful |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Forelimb morphology
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Combined SHIRPA and Dysmorphology / Coat - color pattern - back
|
HOM
|
8f:9m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Eye Morphology / Optic Disc
|
HOM
|
8f:9m
|
Fisher Exact Test framework
|
0.126
|
Successful |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Eye Morphology / Optic Disc
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Adult LacZ / Parotid gland
|
HET
|
1f:1m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Eye Morphology / Narrow eye opening
|
HOM
|
8f:9m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Eye Morphology / Narrow eye opening
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Clinical Chemistry / Glycerol
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.231
|
Successful |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Heart Weight / Heart weight
|
HOM
|
7f:4m
|
Linear Model Using Generalized Least Squares framework, GLS, including Weight
|
0.0401
|
Successful |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Heart Weight / Heart weight
|
HOM
|
8f:9m
|
Linear Mixed Model framework, LME, including Weight
|
0.209
|
Successful |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Vibrissae size
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Dorsal skin appearance
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Adult LacZ / Bone Marrow
|
HET
|
1f:1m
|
|
|
NotProcessed |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Vibrissae colour
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Combined SHIRPA and Dysmorphology / Coat - hair texture / appearance - back
|
HOM
|
8f:9m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Hindpaw footpad size
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
DSS Histology / Section 2 Lamina Propria
|
HOM
|
2f:1m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - S
|
HOM
|
6f:6m
|
Linear Mixed Model framework, LME, including Weight
|
0.0388
|
Successful |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Eye Morphology / Pupil Shape
|
HOM
|
8f:9m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Eye Morphology / Pupil Shape
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Intraperitoneal glucose tolerance test (IPGTT) / Blood glucose concentration
|
HOM
|
35f:31m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Intraperitoneal glucose tolerance test (IPGTT) / Blood glucose concentration
|
HOM
|
40f:45m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Open Field / Periphery average speed
|
HOM
|
8f:9m
|
Linear Mixed Model framework, LME, not including Weight
|
0.703
|
Successful |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Fertility of Homozygous Knock-out Mice / Gross Findings Male
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
X-ray / Cervical processes
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Combined SHIRPA and Dysmorphology / Transfer arousal
|
HOM
|
4f:6m
|
|
|
NotProcessed |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Paw coat/hair colour pattern
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Echo / Stroke Volume
|
HOM
|
8f:9m
|
Linear Mixed Model framework, LME, including Weight
|
0.732
|
Successful |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Three-point Bend / Yield Load
|
HOM
|
2f:m
|
|
|
NotProcessed |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
X-ray / Comment on XRay image
|
HOM
|
5f:6m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Adult LacZ / Main olfactory bulb
|
HET
|
1f:1m
|
|
|
NotProcessed |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Hindpaw nail count
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
DSS Histology / Section 1 Lamina Propria
|
HOM
|
2f:2m
|
|
|
NotProcessed |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Cortical Bone MicroCT / Cortical Thickness
|
HOM
|
2f:m
|
|
|
NotProcessed |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Body Composition (DEXA lean/fat) / Lean/Body weight
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0831
|
Successful |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Body Composition (DEXA lean/fat) / Lean/Body weight
|
HOM
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.886
|
Successful |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Buffy coat peripheral blood leukocyte immunophenotyping / NKT cell percentage
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Open Field / Distance travelled - total
|
HOM
|
8f:9m
|
Linear Mixed Model framework, LME, not including Weight
|
0.727
|
Successful |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Combined SHIRPA and Dysmorphology / Snout size
|
HOM
|
8f:9m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Auditory Brain Stem Response / Click-evoked ABR threshold
|
HOM
|
4f:m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Auditory Brain Stem Response / Click-evoked ABR threshold
|
HOM
|
4f:3m
|
Reference Range Plus Test framework; quantile = 0.95 (Tails probability = 0.025)
|
0.0301
|
Successful |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Eye Morphology / Synechia
|
HOM
|
8f:9m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Eye Morphology / Synechia
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Auditory Brain Stem Response / 24kHz-evoked ABR Threshold
|
HOM
|
4f:m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Auditory Brain Stem Response / 24kHz-evoked ABR Threshold
|
HOM
|
4f:2m
|
Reference Range Plus Test framework; quantile = 0.95 (Tails probability = 0.025)
|
0.0335
|
Successful |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Clinical Chemistry / Total cholesterol
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.285
|
Successful |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Clinical Chemistry / Total cholesterol
|
HOM
|
7f:9m
|
Linear Mixed Model framework, LME, including Weight
|
0.578
|
Successful |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Hindpaw
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Clinical Chemistry / Albumin
|
HOM
|
8f:9m
|
Linear Mixed Model framework, LME, not including Weight
|
0.132
|
Successful |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Clinical Chemistry / Albumin
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.159
|
Successful |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Intraperitoneal glucose tolerance test (IPGTT) / Initial response to glucose challenge
|
HOM
|
7f:6m
|
Linear Mixed Model framework, LME, not including Weight
|
0.714
|
Successful |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Intraperitoneal glucose tolerance test (IPGTT) / Initial response to glucose challenge
|
HOM
|
8f:9m
|
Linear Mixed Model framework, LME, not including Weight
|
0.921
|
Successful |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Electrocardiogram (ECG) / HR
|
HOM
|
8f:9m
|
Linear Mixed Model framework, LME, not including Weight
|
0.940
|
Successful |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Antigen Specific Immunoglobulin Assay / TetC specific IgG1
|
HOM
|
2f:2m
|
|
|
NotProcessed |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
X-ray / Transitional vertebrae
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
X-ray / Pelvis
|
HOM
|
5f:4m
|
|
|
NotProcessed |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
X-ray / Pelvis
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Adult LacZ / Lung
|
HET
|
1f:1m
|
|
|
NotProcessed |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Pinna rotation
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Eye Morphology / Eyelid morphology
|
HOM
|
8f:9m
|
|
|
NotProcessed |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Eye Morphology / Eyelid morphology
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Adult LacZ / Tongue
|
HET
|
1f:1m
|
|
|
NotProcessed |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
X-ray / Shape of spine
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Combined SHIRPA and Dysmorphology / Forelimb digit - shape
|
HOM
|
8f:9m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Adult LacZ / Spleen
|
HET
|
1f:1m
|
|
|
NotProcessed |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Hematology / Mean cell volume
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Hematology / Mean cell volume
|
HOM
|
8f:9m
|
Linear Mixed Model framework, LME, including Weight
|
0.000882
|
Successful |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Combined SHIRPA and Dysmorphology / Coat - color - back
|
HOM
|
8f:9m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Adult LacZ / Mesenteric Lymph Node
|
HET
|
1f:1m
|
|
|
NotProcessed |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Vertebra Compression / Vertebra Max Load
|
HOM
|
2f:m
|
|
|
NotProcessed |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Femoral Microradiography / Femoral Bone Mineral Content
|
HOM
|
2f:m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Open Field / Center permanence time
|
HOM
|
8f:9m
|
Linear Mixed Model framework, LME, not including Weight
|
0.376
|
Successful |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Grip Strength / Forelimb grip strength measurement
|
HOM
|
12f:18m
|
|
|
NotProcessed |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Grip Strength / Forelimb grip strength measurement
|
HOM
|
21f:21m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Combined SHIRPA and Dysmorphology / Hindpaw - size
|
HOM
|
8f:9m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Open Field / Whole arena permanence
|
HOM
|
8f:9m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Combined SHIRPA and Dysmorphology / Upper lip morphology
|
HOM
|
8f:9m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Combined SHIRPA and Dysmorphology / Locomotor activity
|
HOM
|
4f:6m
|
Linear Mixed Model framework, LME, not including Weight
|
0.967
|
Successful |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Buffy coat peripheral blood leukocyte immunophenotyping / B cell CD19+ percentage
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Pinna skin colour
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Adult LacZ / Colon
|
HET
|
1f:1m
|
|
|
NotProcessed |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Salmonella Challenge / Spleen Weight
|
HOM
|
2f:2m
|
|
|
NotProcessed |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Positional passivity
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Forepaw nail length
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Adult LacZ / Lower Urinary Tract
|
HET
|
1f:1m
|
|
|
NotProcessed |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Head coat/hair colour pattern
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Forepaw
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Indirect Calorimetry / Ambulatory activity (no. of beam cuts)
|
HOM
|
f:155m
|
|
|
NotProcessed |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Digit coat/hair length
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Adult LacZ / Ovary
|
HET
|
1f:1m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Electrocardiogram (ECG) / HRV
|
HOM
|
8f:9m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.167
|
Successful |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Eye Morphology / Retinal Blood Vessels
|
HOM
|
8f:9m
|
Fisher Exact Test framework
|
0.00332
|
Successful |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Eye Morphology / Retinal Blood Vessels
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI1
|
HOM
|
6f:6m
|
Linear Mixed Model framework, LME, including Weight
|
0.583
|
Successful |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Trabecular Bone MicroCT / Trabecular Number (mm-1)
|
HOM
|
2f:m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP4
|
HOM
|
6f:6m
|
|
|
NotProcessed |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
DSS Histology / Section 2 Epithelium
|
HOM
|
2f:1m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Adult LacZ / Uterus
|
HET
|
1f:1m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
X-ray / Mandibles
|
HOM
|
5f:4m
|
|
|
NotProcessed |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
X-ray / Mandibles
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Vibrissae
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Pinna touch reflex
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Ventral coat/hair presence
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Combined SHIRPA and Dysmorphology / Skin color - back paws
|
HOM
|
8f:9m
|
|
|
NotProcessed |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Mouth morphology
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Salmonella Challenge / Caecal Contents Counts in 20 micro litres
|
HOM
|
2f:2m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Combined SHIRPA and Dysmorphology / Skin color - whole body
|
HOM
|
8f:9m
|
|
|
NotProcessed |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
X-ray / Number of digits
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
X-ray / Number of digits
|
HOM
|
5f:4m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Combined SHIRPA and Dysmorphology / Coat - hair distribution - abdomen
|
HOM
|
8f:9m
|
|
|
NotProcessed |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
DSS Histology / Average histology score
|
HOM
|
2f:1m
|
|
|
NotProcessed |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Limb coat/hair presence
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Incisors
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Adult LacZ / Brainstem
|
HET
|
1f:1m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Combined SHIRPA and Dysmorphology / Hindlimb nail - shape
|
HOM
|
8f:9m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Combined SHIRPA and Dysmorphology / Coat - hair distribution - head
|
HOM
|
8f:9m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Adult LacZ / Oral epithelium
|
HET
|
1f:1m
|
|
|
NotProcessed |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Hindpaw size
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Vertebral Microradiography / Vertebral Bone Mineral Content
|
HOM
|
2f:m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Clinical Chemistry / Fructosamine
|
HOM
|
7f:9m
|
Linear Mixed Model framework, LME, including Weight
|
0.118
|
Successful |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Clinical Chemistry / Fructosamine
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.269
|
Successful |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Eye Morphology / Corneal Sclerization
|
HOM
|
8f:9m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Clinical Chemistry / Alkaline phosphatase
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.0195
|
Successful |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Clinical Chemistry / Alkaline phosphatase
|
HOM
|
8f:9m
|
Linear Mixed Model framework, LME, including Weight
|
0.0583
|
Successful |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Eye Morphology / Eye Hemorrhage or Blood Presence
|
HOM
|
8f:9m
|
|
|
NotProcessed |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Eye Morphology / Eye Hemorrhage or Blood Presence
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Open Field / Number of rears - total
|
HOM
|
8f:9m
|
Linear Mixed Model framework, LME, not including Weight
|
0.441
|
Successful |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
X-ray / Teeth
|
HOM
|
5f:4m
|
|
|
NotProcessed |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
X-ray / Teeth
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
DSS Histology / Section 1 Area
|
HOM
|
2f:2m
|
|
|
NotProcessed |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Paw coat/hair length
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Cortical Bone MicroCT / Internal Diameter
|
HOM
|
2f:m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Adult LacZ / Submandibular Gland
|
HET
|
1f:1m
|
|
|
NotProcessed |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Buffy coat peripheral blood leukocyte immunophenotyping / CD4+CD44+CD62L- percentage
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Adult LacZ / White Adipose Tissue
|
HET
|
1f:1m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Body Weight / Body weight
|
HOM
|
82f:93m
|
|
|
NotProcessed |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Body Weight / Body weight
|
HOM
|
70f:84m
|
|
|
NotProcessed |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Antigen Specific Immunoglobulin Assay / TetC specific IgG2
|
HOM
|
2f:2m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Eye Morphology / Fusion between cornea and lens
|
HOM
|
8f:9m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Eye Morphology / Fusion between cornea and lens
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Combined SHIRPA and Dysmorphology / Coat - color - head
|
HOM
|
8f:9m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Hematology / Mean corpuscular hemoglobin
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0759
|
Successful |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Hematology / Mean corpuscular hemoglobin
|
HOM
|
8f:9m
|
Linear Mixed Model framework, LME, including Weight
|
0.234
|
Successful |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Tail coat/hair presence
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Forepaw size
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Heart Weight / Heart weight normalised against tibia length
|
HOM
|
8f:9m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Combined SHIRPA and Dysmorphology / Hindlimb digit - shape
|
HOM
|
8f:9m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Combined SHIRPA and Dysmorphology / Forepaw - size
|
HOM
|
8f:9m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Intraperitoneal glucose tolerance test (IPGTT) / Fasted blood glucose concentration
|
HOM
|
8f:9m
|
Linear Mixed Model framework, LME, not including Weight
|
0.297
|
Successful |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Intraperitoneal glucose tolerance test (IPGTT) / Fasted blood glucose concentration
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.368
|
Successful |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Clinical Chemistry / Total bilirubin
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.256
|
Successful |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Clinical Chemistry / Total bilirubin
|
HOM
|
6f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.262
|
Successful |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Indirect Calorimetry / Total activity (no. of fine movement + no. of beam cuts)
|
HOM
|
f:155m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Electrocardiogram (ECG) / CV
|
HOM
|
8f:9m
|
Linear Mixed Model framework, LME, including Weight
|
0.155
|
Successful |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
X-ray / Fusion of ribs
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
X-ray / Fusion of ribs
|
HOM
|
5f:4m
|
|
|
NotProcessed |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Limb grasping
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Eye Morphology / Sheimpflug Lens description
|
HOM
|
8f:9m
|
|
|
NotProcessed |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Body Composition (DEXA lean/fat) / BMC/Body weight
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0369
|
Successful |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Combined SHIRPA and Dysmorphology / Lower lip morphology
|
HOM
|
8f:9m
|
|
|
NotProcessed |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Salmonella Challenge / Spleen Counts in 20 micro litres
|
HOM
|
2f:2m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Adult LacZ / Brown adipose tissue
|
HET
|
1f:1m
|
|
|
NotProcessed |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Head coat/hair appearance
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Forepaw nail count
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Vertebra Compression / Vertebra Stiffness
|
HOM
|
2f:m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Open Field / Center resting time
|
HOM
|
8f:9m
|
Linear Mixed Model framework, LME, including Weight
|
0.453
|
Successful |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Eye Morphology / Retinal Blood Vessels Structure
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Eye Morphology / Retinal Blood Vessels Structure
|
HOM
|
8f:9m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Eye Morphology / Left total retinal thickness
|
HOM
|
8f:9m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0650
|
Successful |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
X-ray / Joints
|
HOM
|
5f:4m
|
|
|
NotProcessed |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
X-ray / Joints
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Adult LacZ / Large Intestine
|
HET
|
1f:1m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Grip Strength / Forelimb and hindlimb grip strength measurement
|
HOM
|
11f:18m
|
|
|
NotProcessed |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Grip Strength / Forelimb and hindlimb grip strength measurement
|
HOM
|
21f:21m
|
|
|
NotProcessed |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Pinna skin appearance
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Combined SHIRPA and Dysmorphology / Gait
|
HOM
|
4f:6m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
X-ray / Fusion of processes
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Hematology / Red blood cell distribution width
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.168
|
Successful |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Hematology / Red blood cell distribution width
|
HOM
|
8f:9m
|
Linear Mixed Model framework, LME, including Weight
|
0.689
|
Successful |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Combined SHIRPA and Dysmorphology / Ears
|
HOM
|
8f:9m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Adult LacZ / Brain
|
HET
|
1f:1m
|
|
|
NotProcessed |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Snout size
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP3
|
HOM
|
6f:6m
|
|
|
NotProcessed |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
DSS Histology / Section 1 Severe Markers
|
HOM
|
2f:2m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP4_S
|
HOM
|
6f:6m
|
|
|
NotProcessed |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
DSS Histology / Total section 2 score
|
HOM
|
2f:1m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Open Field / Whole arena average speed
|
HOM
|
8f:9m
|
Linear Mixed Model framework, LME, not including Weight
|
0.533
|
Successful |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Three-point Bend / Max Load
|
HOM
|
2f:m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Echo / Aortic diameter (Dao)
|
HOM
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.101
|
Successful |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Dorsal coat/hair length
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Ubash3atm1b(KOMP)Wtsi
|
HMGU
|
Combined SHIRPA and Dysmorphology / Skin color - tail
|
HOM
|
8f:9m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Ubash3atm1a(KOMP)Wtsi
|
WTSI
|
Trabecular Bone MicroCT / Bone Volume/Tissue Volume (%)
|
HOM
|
2f:m
|
|
|
NotProcessed |