Tppptm1.1(KOMP)Vlcg
|
JAX
|
Electroconvulsive Threshold Testing / mA threshold inducing clonic seizure
|
HOM
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
8.64×10-15
|
Successful |
Tppptm1.1(KOMP)Vlcg
|
JAX
|
Open Field - centre start / Whole arena average speed
|
HOM
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
1.42×10-08
|
Successful |
Tppptm1.1(KOMP)Vlcg
|
JAX
|
Hole-board Exploration / Holepoke sequence
|
HOM
|
173f:189m
|
|
|
NotProcessed |
Tppptm1.1(KOMP)Vlcg
|
JAX
|
Sleep Wake / Light sleep bout lengths standard deviation
|
HOM
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
2.03×10-07
|
Successful |
Tppptm1.1(KOMP)Vlcg
|
JAX
|
Combined SHIRPA and Dysmorphology / Activity (body position)
|
HOM
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Tppptm1.1(KOMP)Vlcg
|
JAX
|
Combined SHIRPA and Dysmorphology / Head bobbing
|
HOM
|
8f:8m
|
|
|
NotProcessed |
Tppptm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP1
|
HOM
|
5f:2m
|
|
|
NotProcessed |
Tppptm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP1
|
HOM
|
3f:6m
|
|
|
NotProcessed |
Tppptm1.1(KOMP)Vlcg
|
JAX
|
Light-Dark Test / Percent time in light
|
HOM
|
6f:6m
|
Linear Mixed Model framework, LME, including Weight
|
2.79×10-05
|
Successful |
Tppptm1.1(KOMP)Vlcg
|
JAX
|
Open Field - centre start / Center average speed
|
HOM
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.425
|
Successful |
Tppptm1.1(KOMP)Vlcg
|
JAX
|
Combined SHIRPA and Dysmorphology / Trunk curl
|
HOM
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Tppptm1.1(KOMP)Vlcg
|
JAX
|
Open Field - centre start / Center permanence time
|
HOM
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
2.58×10-09
|
Successful |
Tppptm1.1(KOMP)Vlcg
|
JAX
|
Light-Dark Test / Side changes
|
HOM
|
6f:6m
|
Linear Mixed Model framework, LME, including Weight
|
8.15×10-08
|
Successful |
Tppptm1.1(KOMP)Vlcg
|
JAX
|
Hole-board Exploration / Total holepokes
|
HOM
|
6f:6m
|
Linear Mixed Model framework, LME, including Weight
|
0.0527
|
Successful |
Tppptm1.1(KOMP)Vlcg
|
JAX
|
Sleep Wake / Dark sleep bout lengths mean
|
HOM
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.0329
|
Successful |
Tppptm1.1(KOMP)Vlcg
|
JAX
|
Combined SHIRPA and Dysmorphology / Unexpected behaviors
|
HOM
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Tppptm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP2
|
HOM
|
5f:2m
|
|
|
NotProcessed |
Tppptm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP2
|
HOM
|
3f:6m
|
|
|
NotProcessed |
Tppptm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - Global
|
HOM
|
3f:6m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.220
|
Successful |
Tppptm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - Global
|
HOM
|
5f:2m
|
Linear Mixed Model framework, LME, not including Weight
|
0.927
|
Successful |
Tppptm1.1(KOMP)Vlcg
|
JAX
|
Light-Dark Test / Light side time spent
|
HOM
|
6f:6m
|
Linear Mixed Model framework, LME, not including Weight
|
0.00232
|
Successful |
Tppptm1.1(KOMP)Vlcg
|
JAX
|
Open Field - centre start / Periphery distance travelled
|
HOM
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0346
|
Successful |
Tppptm1.1(KOMP)Vlcg
|
JAX
|
Open Field - centre start / Whole arena resting time
|
HOM
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
1.70×10-09
|
Successful |
Tppptm1.1(KOMP)Vlcg
|
JAX
|
Combined SHIRPA and Dysmorphology / Aggression
|
HOM
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Tppptm1.1(KOMP)Vlcg
|
JAX
|
Open Field - centre start / Number of Rears
|
HOM
|
32f:32m
|
|
|
NotProcessed |
Tppptm1.1(KOMP)Vlcg
|
JAX
|
Light-Dark Test / Time mobile light side
|
HOM
|
6f:6m
|
Linear Mixed Model framework, LME, including Weight
|
4.84×10-06
|
Successful |
Tppptm1.1(KOMP)Vlcg
|
JAX
|
Grip Strength / Forelimb grip strength measurement mean
|
HOM
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.268
|
Successful |
Tppptm1.1(KOMP)Vlcg
|
JAX
|
Combined SHIRPA and Dysmorphology / Startle response
|
HOM
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Tppptm1.1(KOMP)Vlcg
|
JAX
|
Sleep Wake / Breath rate during sleep standard deviation
|
HOM
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.000654
|
Successful |
Tppptm1.1(KOMP)Vlcg
|
JAX
|
Open Field - centre start / Percentage center time
|
HOM
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
2.58×10-09
|
Successful |
Tppptm1.1(KOMP)Vlcg
|
JAX
|
Open Field - centre start / Distance travelled
|
HOM
|
32f:32m
|
|
|
NotProcessed |
Tppptm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - BN
|
HOM
|
3f:6m
|
|
|
NotProcessed |
Tppptm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - BN
|
HOM
|
5f:2m
|
|
|
NotProcessed |
Tppptm1.1(KOMP)Vlcg
|
JAX
|
Combined SHIRPA and Dysmorphology / Vocalization
|
HOM
|
8f:8m
|
Fisher Exact Test framework
|
0.619
|
Successful |
Tppptm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP3_S
|
HOM
|
3f:6m
|
|
|
NotProcessed |
Tppptm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP3_S
|
HOM
|
5f:2m
|
|
|
NotProcessed |
Tppptm1.1(KOMP)Vlcg
|
JAX
|
Combined SHIRPA and Dysmorphology / Touch escape
|
HOM
|
2f:2m
|
|
|
NotProcessed |
Tppptm1.1(KOMP)Vlcg
|
JAX
|
Tail Suspension / Time immobile
|
HOM
|
8f:8m
|
Linear Model Using Generalized Least Squares framework, GLS, including Weight
|
0.442
|
Successful |
Tppptm1.1(KOMP)Vlcg
|
JAX
|
Sleep Wake / Sleep daily percent
|
HOM
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.498
|
Successful |
Tppptm1.1(KOMP)Vlcg
|
JAX
|
Light-Dark Test / Dark side time spent
|
HOM
|
6f:6m
|
Linear Mixed Model framework, LME, not including Weight
|
0.00232
|
Successful |
Tppptm1.1(KOMP)Vlcg
|
JAX
|
Grip Strength / Forelimb and hindlimb grip strength measurement mean
|
HOM
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.0719
|
Successful |
Tppptm1.1(KOMP)Vlcg
|
JAX
|
Sleep Wake / Sleep light phase percent
|
HOM
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.0694
|
Successful |
Tppptm1.1(KOMP)Vlcg
|
JAX
|
Open Field - centre start / Number of rears - total
|
HOM
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.563
|
Successful |
Tppptm1.1(KOMP)Vlcg
|
JAX
|
Grip Strength / Forelimb grip strength measurement
|
HOM
|
24f:24m
|
|
|
NotProcessed |
Tppptm1.1(KOMP)Vlcg
|
JAX
|
Rotarod / Latency to fall
|
HOM
|
40f:40m
|
|
|
NotProcessed |
Tppptm1.1(KOMP)Vlcg
|
JAX
|
Tail Suspension / Latency to immobility
|
HOM
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.467
|
Successful |
Tppptm1.1(KOMP)Vlcg
|
JAX
|
Sleep Wake / Peak wake with respect to dark onset median
|
HOM
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.526
|
Successful |
Tppptm1.1(KOMP)Vlcg
|
JAX
|
Grip Strength / Forelimb grip strength normalised against body weight
|
HOM
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.926
|
Successful |
Tppptm1.1(KOMP)Vlcg
|
JAX
|
Combined SHIRPA and Dysmorphology / Locomotor activity
|
HOM
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
8.26×10-05
|
Successful |
Tppptm1.1(KOMP)Vlcg
|
JAX
|
Eye Morphology / Optic Disc
|
HOM
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Tppptm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP2_S
|
HOM
|
3f:6m
|
|
|
NotProcessed |
Tppptm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP2_S
|
HOM
|
5f:2m
|
|
|
NotProcessed |
Tppptm1.1(KOMP)Vlcg
|
JAX
|
Combined SHIRPA and Dysmorphology / Tail elevation
|
HOM
|
8f:8m
|
|
|
NotProcessed |
Tppptm1.1(KOMP)Vlcg
|
JAX
|
Open Field - centre start / Periphery average speed
|
HOM
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
2.78×10-09
|
Successful |
Tppptm1.1(KOMP)Vlcg
|
JAX
|
Light-Dark Test / Time mobile dark side
|
HOM
|
6f:6m
|
Linear Mixed Model framework, LME, including Weight
|
2.35×10-05
|
Successful |
Tppptm1.1(KOMP)Vlcg
|
JAX
|
Light-Dark Test / Fecal boli
|
HOM
|
6f:6m
|
Linear Mixed Model framework, LME, including Weight
|
0.0324
|
Successful |
Tppptm1.1(KOMP)Vlcg
|
JAX
|
Combined SHIRPA and Dysmorphology / Contact righting
|
HOM
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Tppptm1.1(KOMP)Vlcg
|
JAX
|
Sleep Wake / Sleep dark phase percent
|
HOM
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.671
|
Successful |
Tppptm1.1(KOMP)Vlcg
|
JAX
|
Grip Strength / Forelimb and hindlimb grip strength normalised against body weight
|
HOM
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.362
|
Successful |
Tppptm1.1(KOMP)Vlcg
|
JAX
|
Grip Strength / Forelimb and hindlimb grip strength measurement
|
HOM
|
24f:24m
|
|
|
NotProcessed |
Tppptm1.1(KOMP)Vlcg
|
JAX
|
Open Field - centre start / Distance travelled - total
|
HOM
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
1.39×10-08
|
Successful |
Tppptm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP1_S
|
HOM
|
5f:2m
|
|
|
NotProcessed |
Tppptm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP1_S
|
HOM
|
3f:6m
|
|
|
NotProcessed |
Tppptm1.1(KOMP)Vlcg
|
JAX
|
Open Field - centre start / Periphery permanence time
|
HOM
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
2.60×10-09
|
Successful |
Tppptm1.1(KOMP)Vlcg
|
JAX
|
Sleep Wake / Breath rate during sleep mean
|
HOM
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.000112
|
Successful |
Tppptm1.1(KOMP)Vlcg
|
JAX
|
Combined SHIRPA and Dysmorphology / Gait
|
HOM
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Tppptm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI1
|
HOM
|
3f:6m
|
Linear Model Using Generalized Least Squares framework, GLS, including Weight
|
0.0359
|
Successful |
Tppptm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI1
|
HOM
|
5f:2m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.617
|
Successful |
Tppptm1.1(KOMP)Vlcg
|
JAX
|
Rotarod / Learning slope
|
HOM
|
8f:8m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.527
|
Successful |
Tppptm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP4
|
HOM
|
2f:2m
|
|
|
NotProcessed |
Tppptm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI3
|
HOM
|
3f:6m
|
Linear Mixed Model framework, LME, including Weight
|
0.667
|
Successful |
Tppptm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI3
|
HOM
|
5f:2m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.942
|
Successful |
Tppptm1.1(KOMP)Vlcg
|
JAX
|
Sleep Wake / Sleep bout lengths mean
|
HOM
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.00306
|
Successful |
Tppptm1.1(KOMP)Vlcg
|
JAX
|
Combined SHIRPA and Dysmorphology / Tremor
|
HOM
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Tppptm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI2
|
HOM
|
3f:6m
|
Linear Mixed Model framework, LME, including Weight
|
0.544
|
Successful |
Tppptm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI2
|
HOM
|
5f:2m
|
Linear Mixed Model framework, LME, not including Weight
|
0.712
|
Successful |
Tppptm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - S
|
HOM
|
5f:2m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.0101
|
Successful |
Tppptm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - S
|
HOM
|
3f:6m
|
Linear Mixed Model framework, LME, including Weight
|
0.593
|
Successful |
Tppptm1.1(KOMP)Vlcg
|
JAX
|
Light-Dark Test / Latency to first transition into dark
|
HOM
|
6f:6m
|
Linear Mixed Model framework, LME, including Weight
|
0.299
|
Successful |
Tppptm1.1(KOMP)Vlcg
|
JAX
|
Rotarod / Learning difference
|
HOM
|
8f:8m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.168
|
Successful |
Tppptm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI4
|
HOM
|
2f:2m
|
|
|
NotProcessed |
Tppptm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP3
|
HOM
|
5f:2m
|
|
|
NotProcessed |
Tppptm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP3
|
HOM
|
3f:6m
|
|
|
NotProcessed |
Tppptm1.1(KOMP)Vlcg
|
JAX
|
Sleep Wake / Dark sleep bout lengths standard deviation
|
HOM
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.000459
|
Successful |
Tppptm1.1(KOMP)Vlcg
|
JAX
|
Eye Morphology / Pupil Light Response
|
HOM
|
8f:8m
|
Fisher Exact Test framework
|
0.00690
|
Successful |
Tppptm1.1(KOMP)Vlcg
|
JAX
|
Combined SHIRPA and Dysmorphology / Limb grasp
|
HOM
|
8f:8m
|
Fisher Exact Test framework
|
0.390
|
Successful |
Tppptm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP4_S
|
HOM
|
2f:2m
|
|
|
NotProcessed |
Tppptm1.1(KOMP)Vlcg
|
JAX
|
Sleep Wake / Light sleep bout lengths mean
|
HOM
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.00305
|
Successful |
Tppptm1.1(KOMP)Vlcg
|
JAX
|
Combined SHIRPA and Dysmorphology / Transfer arousal
|
HOM
|
8f:8m
|
|
|
NotProcessed |
Tppptm1.1(KOMP)Vlcg
|
JAX
|
Sleep Wake / Sleep bout lengths standard deviation
|
HOM
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
3.84×10-05
|
Successful |
Tppptm1.1(KOMP)Vlcg
|
JAX
|
Light-Dark Test / Percent time in dark
|
HOM
|
6f:6m
|
Linear Mixed Model framework, LME, including Weight
|
2.79×10-05
|
Successful |
Tppptm1.1(KOMP)Vlcg
|
JAX
|
Rotarod / Average duration
|
HOM
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.320
|
Successful |
Tppptm1.1(KOMP)Vlcg
|
JAX
|
Open Field - centre start / Center distance travelled
|
HOM
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
1.91×10-20
|
Successful |