Pgam5tm1b(EUCOMM)Wtsi
|
ICS
|
Open Field / Periphery resting time
|
HOM
|
9f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.408
|
Successful |
Pgam5tm1b(EUCOMM)Wtsi
|
ICS
|
Fear Conditioning / % Freezing duration context-1
|
HOM
|
9f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.00618
|
Successful |
Pgam5tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Activity (body position)
|
HET
|
f:1m
|
|
|
NotProcessed |
Pgam5tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Activity (body position)
|
HOM
|
9f:7m
|
Fisher Exact Test framework
|
0.00995
|
Successful |
Pgam5tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Head bobbing
|
HOM
|
9f:7m
|
|
|
NotProcessed |
Pgam5tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Head bobbing
|
HET
|
f:1m
|
|
|
NotProcessed |
Pgam5tm1b(EUCOMM)Wtsi
|
ICS
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP1
|
HOM
|
9f:8m
|
|
|
NotProcessed |
Pgam5tm1b(EUCOMM)Wtsi
|
ICS
|
Fear Conditioning / % Freezing duration context-2
|
HOM
|
9f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.00936
|
Successful |
Pgam5tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Trunk curl
|
HET
|
f:1m
|
|
|
NotProcessed |
Pgam5tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Trunk curl
|
HOM
|
9f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Pgam5tm1b(EUCOMM)Wtsi
|
ICS
|
Fear Conditioning / % Freezing duration habituation-1
|
HOM
|
9f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0347
|
Successful |
Pgam5tm1b(EUCOMM)Wtsi
|
ICS
|
Indirect Calorimetry / Cumulative food intake
|
HET
|
f:22m
|
|
|
NotProcessed |
Pgam5tm1b(EUCOMM)Wtsi
|
ICS
|
Indirect Calorimetry / Cumulative food intake
|
HOM
|
198f:132m
|
|
|
NotProcessed |
Pgam5tm1b(EUCOMM)Wtsi
|
ICS
|
Open Field / Distance travelled - total
|
HOM
|
9f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.00115
|
Successful |
Pgam5tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Unexpected behaviors
|
HET
|
f:1m
|
|
|
NotProcessed |
Pgam5tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Unexpected behaviors
|
HOM
|
9f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Pgam5tm1b(EUCOMM)Wtsi
|
ICS
|
Open Field / Number of rears - total
|
HOM
|
9f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.112
|
Successful |
Pgam5tm1b(EUCOMM)Wtsi
|
ICS
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP2
|
HOM
|
9f:8m
|
|
|
NotProcessed |
Pgam5tm1b(EUCOMM)Wtsi
|
ICS
|
Fear Conditioning / % Freezing duration context-3
|
HOM
|
9f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0344
|
Successful |
Pgam5tm1b(EUCOMM)Wtsi
|
ICS
|
Fear Conditioning / % Pre-cue freezing total
|
HOM
|
9f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0881
|
Successful |
Pgam5tm1b(EUCOMM)Wtsi
|
ICS
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - Global
|
HOM
|
9f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.415
|
Successful |
Pgam5tm1b(EUCOMM)Wtsi
|
ICS
|
Open Field / Periphery permanence time
|
HOM
|
9f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0655
|
Successful |
Pgam5tm1b(EUCOMM)Wtsi
|
ICS
|
Open Field / Distance travelled
|
HOM
|
36f:28m
|
|
|
NotProcessed |
Pgam5tm1b(EUCOMM)Wtsi
|
ICS
|
Indirect Calorimetry / Total food intake
|
HET
|
f:1m
|
|
|
NotProcessed |
Pgam5tm1b(EUCOMM)Wtsi
|
ICS
|
Indirect Calorimetry / Total food intake
|
HOM
|
9f:6m
|
Linear Mixed Model framework, LME, including Weight
|
0.00532
|
Successful |
Pgam5tm1b(EUCOMM)Wtsi
|
ICS
|
Rotarod / Latency to fall mean
|
HOM
|
9f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.304
|
Successful |
Pgam5tm1b(EUCOMM)Wtsi
|
ICS
|
Open Field / Latency to center entry
|
HOM
|
9f:7m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
8.75×10-08
|
Successful |
Pgam5tm1b(EUCOMM)Wtsi
|
ICS
|
Fear Conditioning / % Context freezing total
|
HOM
|
9f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.00433
|
Successful |
Pgam5tm1b(EUCOMM)Wtsi
|
ICS
|
Open Field / Percentage center time
|
HOM
|
9f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0655
|
Successful |
Pgam5tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Aggression
|
HET
|
f:1m
|
|
|
NotProcessed |
Pgam5tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Aggression
|
HOM
|
9f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Pgam5tm1b(EUCOMM)Wtsi
|
ICS
|
Fear Conditioning / % Freezing duration cue-2
|
HOM
|
9f:8m
|
|
|
NotProcessed |
Pgam5tm1b(EUCOMM)Wtsi
|
ICS
|
Open Field / Number of center entries
|
HOM
|
9f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.00192
|
Successful |
Pgam5tm1b(EUCOMM)Wtsi
|
ICS
|
Fear Conditioning / % Cue freezing total
|
HOM
|
9f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.186
|
Successful |
Pgam5tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Startle response
|
HET
|
f:1m
|
|
|
NotProcessed |
Pgam5tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Startle response
|
HOM
|
9f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Pgam5tm1b(EUCOMM)Wtsi
|
ICS
|
Grip Strength / Forelimb grip strength measurement mean
|
HOM
|
9f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.380
|
Successful |
Pgam5tm1b(EUCOMM)Wtsi
|
ICS
|
Rotarod / Latency to fall
|
HOM
|
27f:24m
|
|
|
NotProcessed |
Pgam5tm1b(EUCOMM)Wtsi
|
ICS
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - BN
|
HOM
|
9f:8m
|
|
|
NotProcessed |
Pgam5tm1b(EUCOMM)Wtsi
|
ICS
|
Indirect Calorimetry / Total activity (no. of fine movement + no. of beam cuts)
|
HET
|
f:22m
|
|
|
NotProcessed |
Pgam5tm1b(EUCOMM)Wtsi
|
ICS
|
Indirect Calorimetry / Total activity (no. of fine movement + no. of beam cuts)
|
HOM
|
198f:132m
|
|
|
NotProcessed |
Pgam5tm1b(EUCOMM)Wtsi
|
ICS
|
Open Field / Number of Rears
|
HOM
|
36f:28m
|
|
|
NotProcessed |
Pgam5tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Vocalization
|
HET
|
f:1m
|
|
|
NotProcessed |
Pgam5tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Vocalization
|
HOM
|
9f:7m
|
Fisher Exact Test framework
|
0.709
|
Successful |
Pgam5tm1b(EUCOMM)Wtsi
|
ICS
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP3_S
|
HOM
|
9f:8m
|
|
|
NotProcessed |
Pgam5tm1b(EUCOMM)Wtsi
|
ICS
|
Open Field / Periphery distance travelled
|
HOM
|
9f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.268
|
Successful |
Pgam5tm1b(EUCOMM)Wtsi
|
ICS
|
Grip Strength / Forelimb and hindlimb grip strength measurement mean
|
HOM
|
9f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.529
|
Successful |
Pgam5tm1b(EUCOMM)Wtsi
|
ICS
|
Indirect Calorimetry / Cumulative water intake
|
HET
|
f:22m
|
|
|
NotProcessed |
Pgam5tm1b(EUCOMM)Wtsi
|
ICS
|
Indirect Calorimetry / Cumulative water intake
|
HOM
|
198f:88m
|
|
|
NotProcessed |
Pgam5tm1b(EUCOMM)Wtsi
|
ICS
|
Open Field / Center permanence time
|
HOM
|
9f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0655
|
Successful |
Pgam5tm1b(EUCOMM)Wtsi
|
ICS
|
Grip Strength / Forelimb grip strength measurement
|
HOM
|
27f:24m
|
|
|
NotProcessed |
Pgam5tm1b(EUCOMM)Wtsi
|
ICS
|
Open Field / Whole arena resting time
|
HOM
|
9f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.514
|
Successful |
Pgam5tm1b(EUCOMM)Wtsi
|
ICS
|
Fear Conditioning / % Freezing duration pre-cue-2
|
HOM
|
9f:8m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.0274
|
Successful |
Pgam5tm1b(EUCOMM)Wtsi
|
ICS
|
Fear Conditioning / Freezing duration habituation
|
HOM
|
18f:16m
|
|
|
NotProcessed |
Pgam5tm1b(EUCOMM)Wtsi
|
ICS
|
Grip Strength / Forelimb grip strength normalised against body weight
|
HOM
|
9f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.781
|
Successful |
Pgam5tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Locomotor activity
|
HET
|
f:1m
|
|
|
NotProcessed |
Pgam5tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Locomotor activity
|
HOM
|
9f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
8.01×10-12
|
Successful |
Pgam5tm1b(EUCOMM)Wtsi
|
ICS
|
Open Field / Center resting time
|
HOM
|
9f:7m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.103
|
Successful |
Pgam5tm1b(EUCOMM)Wtsi
|
ICS
|
Open Field / Percentage center movement time
|
HOM
|
9f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.197
|
Successful |
Pgam5tm1b(EUCOMM)Wtsi
|
ICS
|
Eye Morphology / Optic Disc
|
HOM
|
9f:6m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Pgam5tm1b(EUCOMM)Wtsi
|
ICS
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP2_S
|
HOM
|
9f:8m
|
|
|
NotProcessed |
Pgam5tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Tail elevation
|
HOM
|
9f:7m
|
|
|
NotProcessed |
Pgam5tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Tail elevation
|
HET
|
f:1m
|
|
|
NotProcessed |
Pgam5tm1b(EUCOMM)Wtsi
|
ICS
|
Open Field / Center average speed
|
HOM
|
9f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.0244
|
Successful |
Pgam5tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Contact righting
|
HET
|
f:1m
|
|
|
NotProcessed |
Pgam5tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Contact righting
|
HOM
|
9f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Pgam5tm1b(EUCOMM)Wtsi
|
ICS
|
Grip Strength / Forelimb and hindlimb grip strength normalised against body weight
|
HOM
|
9f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.743
|
Successful |
Pgam5tm1b(EUCOMM)Wtsi
|
ICS
|
Fear Conditioning / Freezing duration post-us
|
HOM
|
9f:8m
|
|
|
NotProcessed |
Pgam5tm1b(EUCOMM)Wtsi
|
ICS
|
Rotarod / Passive rotation
|
HOM
|
27f:24m
|
|
|
NotProcessed |
Pgam5tm1b(EUCOMM)Wtsi
|
ICS
|
Grip Strength / Forelimb and hindlimb grip strength measurement
|
HOM
|
27f:24m
|
|
|
NotProcessed |
Pgam5tm1b(EUCOMM)Wtsi
|
ICS
|
Indirect Calorimetry / Ambulatory activity (no. of beam cuts)
|
HOM
|
198f:132m
|
|
|
NotProcessed |
Pgam5tm1b(EUCOMM)Wtsi
|
ICS
|
Indirect Calorimetry / Ambulatory activity (no. of beam cuts)
|
HET
|
f:22m
|
|
|
NotProcessed |
Pgam5tm1b(EUCOMM)Wtsi
|
ICS
|
Fear Conditioning / % Freezing duration cue-1
|
HOM
|
9f:8m
|
|
|
NotProcessed |
Pgam5tm1b(EUCOMM)Wtsi
|
ICS
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP1_S
|
HOM
|
9f:8m
|
|
|
NotProcessed |
Pgam5tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Gait
|
HOM
|
9f:7m
|
|
|
NotProcessed |
Pgam5tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Gait
|
HET
|
f:1m
|
|
|
NotProcessed |
Pgam5tm1b(EUCOMM)Wtsi
|
ICS
|
Hot Plate / Hot plate latency
|
HOM
|
9f:6m
|
|
|
NotProcessed |
Pgam5tm1b(EUCOMM)Wtsi
|
ICS
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI1
|
HOM
|
9f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.422
|
Successful |
Pgam5tm1b(EUCOMM)Wtsi
|
ICS
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP4
|
HOM
|
9f:8m
|
|
|
NotProcessed |
Pgam5tm1b(EUCOMM)Wtsi
|
ICS
|
Fear Conditioning / % Freezing duration habituation-2
|
HOM
|
9f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.368
|
Successful |
Pgam5tm1b(EUCOMM)Wtsi
|
ICS
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI3
|
HOM
|
9f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.895
|
Successful |
Pgam5tm1b(EUCOMM)Wtsi
|
ICS
|
Fear Conditioning / Freezing duration context
|
HOM
|
27f:24m
|
|
|
NotProcessed |
Pgam5tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Tremor
|
HET
|
f:1m
|
|
|
NotProcessed |
Pgam5tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Tremor
|
HOM
|
9f:7m
|
Fisher Exact Test framework
|
0.0218
|
Successful |
Pgam5tm1b(EUCOMM)Wtsi
|
ICS
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI2
|
HOM
|
9f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.885
|
Successful |
Pgam5tm1b(EUCOMM)Wtsi
|
ICS
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - S
|
HOM
|
9f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0147
|
Successful |
Pgam5tm1b(EUCOMM)Wtsi
|
ICS
|
Hot Plate / Type of response
|
HOM
|
9f:6m
|
|
|
NotProcessed |
Pgam5tm1b(EUCOMM)Wtsi
|
ICS
|
Open Field / Periphery average speed
|
HOM
|
9f:7m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.00197
|
Successful |
Pgam5tm1b(EUCOMM)Wtsi
|
ICS
|
Fear Conditioning / Freezing duration cue
|
HOM
|
18f:16m
|
|
|
NotProcessed |
Pgam5tm1b(EUCOMM)Wtsi
|
ICS
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI4
|
HOM
|
9f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.293
|
Successful |
Pgam5tm1b(EUCOMM)Wtsi
|
ICS
|
Indirect Calorimetry / Total water intake
|
HET
|
f:1m
|
|
|
NotProcessed |
Pgam5tm1b(EUCOMM)Wtsi
|
ICS
|
Indirect Calorimetry / Total water intake
|
HOM
|
9f:6m
|
Linear Mixed Model framework, LME, including Weight
|
0.0358
|
Successful |
Pgam5tm1b(EUCOMM)Wtsi
|
ICS
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP3
|
HOM
|
9f:8m
|
|
|
NotProcessed |
Pgam5tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Limb grasp
|
HET
|
f:1m
|
|
|
NotProcessed |
Pgam5tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Limb grasp
|
HOM
|
9f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Pgam5tm1b(EUCOMM)Wtsi
|
ICS
|
Eye Morphology / Pupil Light Response
|
HOM
|
9f:6m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Pgam5tm1b(EUCOMM)Wtsi
|
ICS
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP4_S
|
HOM
|
9f:8m
|
|
|
NotProcessed |
Pgam5tm1b(EUCOMM)Wtsi
|
ICS
|
Open Field / Whole arena average speed
|
HOM
|
9f:7m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.000236
|
Successful |
Pgam5tm1b(EUCOMM)Wtsi
|
ICS
|
Fear Conditioning / % Freezing duration pre-cue-1
|
HOM
|
9f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.409
|
Successful |
Pgam5tm1b(EUCOMM)Wtsi
|
ICS
|
Fear Conditioning / Context freezing total
|
HOM
|
9f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.00451
|
Successful |
Pgam5tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Transfer arousal
|
HET
|
f:1m
|
|
|
NotProcessed |
Pgam5tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Transfer arousal
|
HOM
|
9f:7m
|
|
|
NotProcessed |
Pgam5tm1b(EUCOMM)Wtsi
|
ICS
|
Open Field / Center distance travelled
|
HOM
|
9f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.0155
|
Successful |
Pgam5tm1b(EUCOMM)Wtsi
|
ICS
|
Fear Conditioning / Freezing duration pre-cue
|
HOM
|
18f:16m
|
|
|
NotProcessed |