Ydjctm1.1(KOMP)Vlcg
|
JAX
|
Electroconvulsive Threshold Testing / mA threshold inducing clonic seizure
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.151
|
Successful |
Ydjctm1.1(KOMP)Vlcg
|
JAX
|
Open Field - centre start / Whole arena average speed
|
HOM
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.202
|
Successful |
Ydjctm1(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Gait (inc. ataxia)
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Ydjctm1.1(KOMP)Vlcg
|
JAX
|
Hole-board Exploration / Holepoke sequence
|
HOM
|
341f:352m
|
|
|
NotProcessed |
Ydjctm1.1(KOMP)Vlcg
|
JAX
|
Sleep Wake / Light sleep bout lengths standard deviation
|
HOM
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.285
|
Successful |
Ydjctm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP1
|
HOM
|
8f:4m
|
|
|
NotProcessed |
Ydjctm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP1
|
HOM
|
f:4m
|
|
|
NotProcessed |
Ydjctm1.1(KOMP)Vlcg
|
JAX
|
Light-Dark Test / Percent time in light
|
HOM
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.281
|
Successful |
Ydjctm1.1(KOMP)Vlcg
|
JAX
|
Open Field - centre start / Center average speed
|
HOM
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0464
|
Successful |
Ydjctm1.1(KOMP)Vlcg
|
JAX
|
Open Field - centre start / Center permanence time
|
HOM
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.184
|
Successful |
Ydjctm1.1(KOMP)Vlcg
|
JAX
|
Light-Dark Test / Side changes
|
HOM
|
8f:8m
|
Linear Model Using Generalized Least Squares framework, GLS, including Weight
|
0.00706
|
Successful |
Ydjctm1(KOMP)Wtsi
|
WTSI
|
Indirect Calorimetry / Cumulative food intake
|
HOM
|
f:87m
|
|
|
NotProcessed |
Ydjctm1.1(KOMP)Vlcg
|
JAX
|
Hole-board Exploration / Total holepokes
|
HOM
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.360
|
Successful |
Ydjctm1(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Transfer arousal
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
0.186
|
Successful |
Ydjctm1.1(KOMP)Vlcg
|
JAX
|
Sleep Wake / Dark sleep bout lengths mean
|
HOM
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.953
|
Successful |
Ydjctm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP2
|
HOM
|
8f:4m
|
|
|
NotProcessed |
Ydjctm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP2
|
HOM
|
f:4m
|
|
|
NotProcessed |
Ydjctm1(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Convulsions
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Ydjctm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - Global
|
HOM
|
8f:4m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.676
|
Successful |
Ydjctm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - Global
|
HOM
|
f:4m
|
Linear Mixed Model framework, LME, not including Weight
|
0.919
|
Successful |
Ydjctm1.1(KOMP)Vlcg
|
JAX
|
Light-Dark Test / Light side time spent
|
HOM
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.216
|
Successful |
Ydjctm1.1(KOMP)Vlcg
|
JAX
|
Open Field - centre start / Periphery distance travelled
|
HOM
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.147
|
Successful |
Ydjctm1(KOMP)Wtsi
|
WTSI
|
Indirect Calorimetry / Total food intake
|
HOM
|
f:4m
|
Linear Mixed Model framework, LME, including Weight
|
0.000383
|
Successful |
Ydjctm1.1(KOMP)Vlcg
|
JAX
|
Open Field - centre start / Whole arena resting time
|
HOM
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.273
|
Successful |
Ydjctm1(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Trunk curl
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Ydjctm1.1(KOMP)Vlcg
|
JAX
|
Open Field - centre start / Number of Rears
|
HOM
|
32f:32m
|
|
|
NotProcessed |
Ydjctm1.1(KOMP)Vlcg
|
JAX
|
Light-Dark Test / Time mobile light side
|
HOM
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.665
|
Successful |
Ydjctm1.1(KOMP)Vlcg
|
JAX
|
Grip Strength / Forelimb grip strength measurement mean
|
HOM
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.0430
|
Successful |
Ydjctm1(KOMP)Wtsi
|
WTSI
|
Grip Strength / Forelimb grip strength measurement mean
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.383
|
Successful |
Ydjctm1.1(KOMP)Vlcg
|
JAX
|
Sleep Wake / Breath rate during sleep standard deviation
|
HOM
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.122
|
Successful |
Ydjctm1.1(KOMP)Vlcg
|
JAX
|
Open Field - centre start / Percentage center time
|
HOM
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.184
|
Successful |
Ydjctm1.1(KOMP)Vlcg
|
JAX
|
Open Field - centre start / Distance travelled
|
HOM
|
32f:32m
|
|
|
NotProcessed |
Ydjctm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - BN
|
HOM
|
f:4m
|
|
|
NotProcessed |
Ydjctm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - BN
|
HOM
|
8f:4m
|
|
|
NotProcessed |
Ydjctm1(KOMP)Wtsi
|
WTSI
|
Indirect Calorimetry / Total activity (no. of fine movement + no. of beam cuts)
|
HOM
|
f:87m
|
|
|
NotProcessed |
Ydjctm1(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Limb grasping
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Ydjctm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP3_S
|
HOM
|
8f:4m
|
|
|
NotProcessed |
Ydjctm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP3_S
|
HOM
|
f:4m
|
|
|
NotProcessed |
Ydjctm1.1(KOMP)Vlcg
|
JAX
|
Sleep Wake / Sleep daily percent
|
HOM
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0178
|
Successful |
Ydjctm1.1(KOMP)Vlcg
|
JAX
|
Light-Dark Test / Dark side time spent
|
HOM
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.216
|
Successful |
Ydjctm1.1(KOMP)Vlcg
|
JAX
|
Grip Strength / Forelimb and hindlimb grip strength measurement mean
|
HOM
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.0224
|
Successful |
Ydjctm1(KOMP)Wtsi
|
WTSI
|
Grip Strength / Forelimb and hindlimb grip strength measurement mean
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.499
|
Successful |
Ydjctm1.1(KOMP)Vlcg
|
JAX
|
Sleep Wake / Sleep light phase percent
|
HOM
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.00319
|
Successful |
Ydjctm1.1(KOMP)Vlcg
|
JAX
|
Open Field - centre start / Number of rears - total
|
HOM
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.753
|
Successful |
Ydjctm1(KOMP)Wtsi
|
WTSI
|
Grip Strength / Forelimb grip strength measurement
|
HOM
|
21f:21m
|
|
|
NotProcessed |
Ydjctm1.1(KOMP)Vlcg
|
JAX
|
Grip Strength / Forelimb grip strength measurement
|
HOM
|
24f:24m
|
|
|
NotProcessed |
Ydjctm1.1(KOMP)Vlcg
|
JAX
|
Rotarod / Latency to fall
|
HOM
|
40f:40m
|
|
|
NotProcessed |
Ydjctm1.1(KOMP)Vlcg
|
JAX
|
Sleep Wake / Peak wake with respect to dark onset median
|
HOM
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.748
|
Successful |
Ydjctm1.1(KOMP)Vlcg
|
JAX
|
Grip Strength / Forelimb grip strength normalised against body weight
|
HOM
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0505
|
Successful |
Ydjctm1(KOMP)Wtsi
|
WTSI
|
Grip Strength / Forelimb grip strength normalised against body weight
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.197
|
Successful |
Ydjctm1.1(KOMP)Vlcg
|
JAX
|
Eye Morphology / Optic Disc
|
HOM
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Ydjctm1(KOMP)Wtsi
|
WTSI
|
Eye Morphology / Optic Disc
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Ydjctm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP2_S
|
HOM
|
8f:4m
|
|
|
NotProcessed |
Ydjctm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP2_S
|
HOM
|
f:4m
|
|
|
NotProcessed |
Ydjctm1.1(KOMP)Vlcg
|
JAX
|
Light-Dark Test / Time mobile dark side
|
HOM
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.000806
|
Successful |
Ydjctm1.1(KOMP)Vlcg
|
JAX
|
Open Field - centre start / Periphery average speed
|
HOM
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.345
|
Successful |
Ydjctm1.1(KOMP)Vlcg
|
JAX
|
Light-Dark Test / Fecal boli
|
HOM
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0684
|
Successful |
Ydjctm1.1(KOMP)Vlcg
|
JAX
|
Sleep Wake / Sleep dark phase percent
|
HOM
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.894
|
Successful |
Ydjctm1.1(KOMP)Vlcg
|
JAX
|
Grip Strength / Forelimb and hindlimb grip strength normalised against body weight
|
HOM
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0427
|
Successful |
Ydjctm1(KOMP)Wtsi
|
WTSI
|
Grip Strength / Forelimb and hindlimb grip strength normalised against body weight
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.925
|
Successful |
Ydjctm1.1(KOMP)Vlcg
|
JAX
|
Grip Strength / Forelimb and hindlimb grip strength measurement
|
HOM
|
24f:24m
|
|
|
NotProcessed |
Ydjctm1(KOMP)Wtsi
|
WTSI
|
Grip Strength / Forelimb and hindlimb grip strength measurement
|
HOM
|
21f:21m
|
|
|
NotProcessed |
Ydjctm1(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Positional passivity
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Ydjctm1.1(KOMP)Vlcg
|
JAX
|
Open Field - centre start / Distance travelled - total
|
HOM
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.204
|
Successful |
Ydjctm1(KOMP)Wtsi
|
WTSI
|
Indirect Calorimetry / Ambulatory activity (no. of beam cuts)
|
HOM
|
f:87m
|
|
|
NotProcessed |
Ydjctm1(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Corneal touch reflex
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Ydjctm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP1_S
|
HOM
|
f:4m
|
|
|
NotProcessed |
Ydjctm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP1_S
|
HOM
|
8f:4m
|
|
|
NotProcessed |
Ydjctm1.1(KOMP)Vlcg
|
JAX
|
Sleep Wake / Breath rate during sleep mean
|
HOM
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.00201
|
Successful |
Ydjctm1.1(KOMP)Vlcg
|
JAX
|
Open Field - centre start / Periphery permanence time
|
HOM
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.183
|
Successful |
Ydjctm1.1(KOMP)Vlcg
|
JAX
|
Rotarod / Learning slope
|
HOM
|
8f:8m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.399
|
Successful |
Ydjctm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI1
|
HOM
|
f:4m
|
Linear Mixed Model framework, LME, not including Weight
|
0.652
|
Successful |
Ydjctm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI1
|
HOM
|
8f:4m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.673
|
Successful |
Ydjctm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP4
|
HOM
|
f:4m
|
|
|
NotProcessed |
Ydjctm1(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Contact righting reflex
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Ydjctm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI3
|
HOM
|
8f:4m
|
Linear Mixed Model framework, LME, including Weight
|
0.307
|
Successful |
Ydjctm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI3
|
HOM
|
f:4m
|
Linear Mixed Model framework, LME, not including Weight
|
0.862
|
Successful |
Ydjctm1.1(KOMP)Vlcg
|
JAX
|
Sleep Wake / Sleep bout lengths mean
|
HOM
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.881
|
Successful |
Ydjctm1(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Startle response
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Ydjctm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI2
|
HOM
|
f:4m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.543
|
Successful |
Ydjctm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI2
|
HOM
|
8f:4m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.985
|
Successful |
Ydjctm1(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Pinna touch reflex
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Ydjctm1.1(KOMP)Vlcg
|
JAX
|
Light-Dark Test / Latency to first transition into dark
|
HOM
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.00412
|
Successful |
Ydjctm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - S
|
HOM
|
f:4m
|
Linear Mixed Model framework, LME, not including Weight
|
0.245
|
Successful |
Ydjctm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - S
|
HOM
|
8f:4m
|
Linear Mixed Model framework, LME, including Weight
|
0.550
|
Successful |
Ydjctm1.1(KOMP)Vlcg
|
JAX
|
Rotarod / Learning difference
|
HOM
|
8f:8m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.578
|
Successful |
Ydjctm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI4
|
HOM
|
f:4m
|
Linear Mixed Model framework, LME, not including Weight
|
0.173
|
Successful |
Ydjctm1(KOMP)Wtsi
|
WTSI
|
Indirect Calorimetry / Total water intake
|
HOM
|
f:4m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0233
|
Successful |
Ydjctm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP3
|
HOM
|
8f:4m
|
|
|
NotProcessed |
Ydjctm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP3
|
HOM
|
f:4m
|
|
|
NotProcessed |
Ydjctm1.1(KOMP)Vlcg
|
JAX
|
Sleep Wake / Dark sleep bout lengths standard deviation
|
HOM
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.266
|
Successful |
Ydjctm1(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Head bobbing/circling
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Ydjctm1(KOMP)Wtsi
|
WTSI
|
Eye Morphology / Pupil Light Response
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Ydjctm1.1(KOMP)Vlcg
|
JAX
|
Eye Morphology / Pupil Light Response
|
HOM
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Ydjctm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP4_S
|
HOM
|
f:4m
|
|
|
NotProcessed |
Ydjctm1(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Tail elevation
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Ydjctm1.1(KOMP)Vlcg
|
JAX
|
Sleep Wake / Light sleep bout lengths mean
|
HOM
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.490
|
Successful |
Ydjctm1.1(KOMP)Vlcg
|
JAX
|
Sleep Wake / Sleep bout lengths standard deviation
|
HOM
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.458
|
Successful |
Ydjctm1.1(KOMP)Vlcg
|
JAX
|
Light-Dark Test / Percent time in dark
|
HOM
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.281
|
Successful |
Ydjctm1(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Tremor
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Ydjctm1.1(KOMP)Vlcg
|
JAX
|
Rotarod / Average duration
|
HOM
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.782
|
Successful |
Ydjctm1.1(KOMP)Vlcg
|
JAX
|
Open Field - centre start / Center distance travelled
|
HOM
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.797
|
Successful |