All nervous system phenotype, behavior/neurological phenotype data for Serpina1f

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Allele Center Procedure / Parameter Zygosity Mutants Statistical
Method
P Value Status Graph
Serpina1fem1(IMPC)J JAX Open Field / Center permanence time HOM 7f:5m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.43481 Success
Serpina1fem1(IMPC)J JAX Open Field / Whole arena resting time HOM 7f:5m Mixed Model framework, linear mixed-effects model, equation withWeight 0.12760 Success
Serpina1fem1(IMPC)J JAX Combined SHIRPA and Dysmorphology / Activity (body position) HOM 8f:7m Fisher Exact Test framework 0.029410 Success
Serpina1fem1(IMPC)J JAX Combined SHIRPA and Dysmorphology / Head bobbing HOM 8f:7m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Serpina1fem1(IMPC)J JAX Grip Strength / Forelimb grip strength normalised against body weight HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.37468 Success
Serpina1fem1(IMPC)J JAX Light-Dark Test / Percent time in light HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.52053 Success
Serpina1fem1(IMPC)J JAX Combined SHIRPA and Dysmorphology / Trunk curl HOM 8f:7m Fisher Exact Test framework 1.0000 Success
Serpina1fem1(IMPC)J JAX Combined SHIRPA and Dysmorphology / Locomotor activity HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.025598 Success
Serpina1fem1(IMPC)J JAX Eye Morphology / Optic Disc HOM 8f:7m Fisher Exact Test framework 1.0000 Success
Serpina1fem1(IMPC)J JAX Light-Dark Test / Time mobile dark side HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.78023 Success
Serpina1fem1(IMPC)J JAX Light-Dark Test / Fecal boli HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.41857 Success
Serpina1fem1(IMPC)J JAX Open Field / Center average speed HOM 7f:5m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.66010 Success
Serpina1fem1(IMPC)J JAX Light-Dark Test / Side changes HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.44604 Success
Serpina1fem1(IMPC)J JAX Combined SHIRPA and Dysmorphology / Contact righting HOM 8f:7m Fisher Exact Test framework 1.0000 Success
Serpina1fem1(IMPC)J JAX Grip Strength / Forelimb and hindlimb grip strength normalised against body weight HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.12189 Success
Serpina1fem1(IMPC)J JAX Hole-board Exploration / Total holepokes HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.58470 Success
Serpina1fem1(IMPC)J JAX Open Field / Distance travelled - total HOM 7f:5m Mixed Model framework, linear mixed-effects model, equation withWeight 0.21978 Success
Serpina1fem1(IMPC)J JAX Open Field / Number of rears - total HOM 7f:5m Mixed Model framework, linear mixed-effects model, equation withWeight 0.44103 Success
Serpina1fem1(IMPC)J JAX Combined SHIRPA and Dysmorphology / Unexpected behaviors HOM 8f:7m Fisher Exact Test framework 1.0000 Success
Serpina1fem1(IMPC)J JAX Light-Dark Test / Light side time spent HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.028302 Success
Serpina1fem1(IMPC)J JAX Open Field / Periphery permanence time HOM 7f:5m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.43526 Success
Serpina1fem1(IMPC)J JAX Combined SHIRPA and Dysmorphology / Gait HOM 8f:7m Fisher Exact Test framework 1.0000 Success
Serpina1fem1(IMPC)J JAX Rotarod / Learning slope HOM 8f:6m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.17224 Success
Serpina1fem1(IMPC)J JAX Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI1 HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.42917 Success
Serpina1fem1(IMPC)J JAX Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI3 HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.50142 Success
Serpina1fem1(IMPC)J JAX Open Field / Percentage center time HOM 7f:5m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.43480 Success
Serpina1fem1(IMPC)J JAX Combined SHIRPA and Dysmorphology / Aggression HOM 8f:7m Fisher Exact Test framework 1.0000 Success
Serpina1fem1(IMPC)J JAX Light-Dark Test / Time mobile light side HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.33841 Success
Serpina1fem1(IMPC)J JAX Combined SHIRPA and Dysmorphology / Tremor HOM 8f:7m Fisher Exact Test framework 0.029410 Success
Serpina1fem1(IMPC)J JAX Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI2 HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.59779 Success
Serpina1fem1(IMPC)J JAX Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - S HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0083621 Success
Serpina1fem1(IMPC)J JAX Light-Dark Test / Latency to first transition into dark HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.10749 Success
Serpina1fem1(IMPC)J JAX Rotarod / Learning difference HOM 8f:6m Mixed Model framework, generalized least squares, equation withoutWeight 0.13657 Success
Serpina1fem1(IMPC)J JAX Grip Strength / Forelimb grip strength measurement mean HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.99308 Success
Serpina1fem1(IMPC)J JAX Combined SHIRPA and Dysmorphology / Startle response HOM 8f:7m Fisher Exact Test framework 1.0000 Success
Serpina1fem1(IMPC)J JAX Open Field / Periphery average speed HOM 7f:5m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.37269 Success
Serpina1fem1(IMPC)J JAX Combined SHIRPA and Dysmorphology / Limb grasp HOM 8f:7m Fisher Exact Test framework 0.047778 Success
Serpina1fem1(IMPC)J JAX Eye Morphology / Pupil Light Response HOM 8f:7m Fisher Exact Test framework 1.0000 Success
Serpina1fem1(IMPC)J JAX Open Field / Whole arena average speed HOM 7f:5m Mixed Model framework, linear mixed-effects model, equation withWeight 0.21935 Success
Serpina1fem1(IMPC)J JAX Open Field / Center distance travelled HOM 7f:5m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.20779 Success
Serpina1fem1(IMPC)J JAX Light-Dark Test / Percent time in dark HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.52053 Success
Serpina1fem1(IMPC)J JAX Combined SHIRPA and Dysmorphology / Vocalization HOM 8f:7m Fisher Exact Test framework 1.0000 Success
Serpina1fem1(IMPC)J JAX Open Field / Periphery distance travelled HOM 7f:5m Mixed Model framework, linear mixed-effects model, equation withWeight 0.45393 Success
Serpina1fem1(IMPC)J JAX Rotarod / Average duration HOM 8f:6m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.98497 Success
Serpina1fem1(IMPC)J JAX Light-Dark Test / Dark side time spent HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.028302 Success
Serpina1fem1(IMPC)J JAX Grip Strength / Forelimb and hindlimb grip strength measurement mean HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.42481 Success

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