All behavior/neurological phenotype, nervous system phenotype data for Serpina1f

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Allele Center Procedure / Parameter Zygosity Mutants Statistical
Method
P Value Status Graph
Serpina1fem1(IMPC)J JAX Open Field / Center permanence time HOM 7f:5m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.44682 Success
Serpina1fem1(IMPC)J JAX Open Field / Whole arena resting time HOM 7f:5m Mixed Model framework, linear mixed-effects model, equation withWeight 0.13261 Success
Serpina1fem1(IMPC)J JAX Combined SHIRPA and Dysmorphology / Activity (body position) HOM 8f:7m Fisher Exact Test framework 0.015517 Success
Serpina1fem1(IMPC)J JAX Combined SHIRPA and Dysmorphology / Head bobbing HOM 8f:7m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Serpina1fem1(IMPC)J JAX Grip Strength / Forelimb grip strength normalised against body weight HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.36816 Success
Serpina1fem1(IMPC)J JAX Light-Dark Test / Percent time in light HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.53709 Success
Serpina1fem1(IMPC)J JAX Combined SHIRPA and Dysmorphology / Trunk curl HOM 8f:7m Fisher Exact Test framework 1.0000 Success
Serpina1fem1(IMPC)J JAX Combined SHIRPA and Dysmorphology / Locomotor activity HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.026239 Success
Serpina1fem1(IMPC)J JAX Eye Morphology / Optic Disc HOM 8f:7m Fisher Exact Test framework 1.0000 Success
Serpina1fem1(IMPC)J JAX Light-Dark Test / Time mobile dark side HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.79104 Success
Serpina1fem1(IMPC)J JAX Light-Dark Test / Fecal boli HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.45000 Success
Serpina1fem1(IMPC)J JAX Open Field / Center average speed HOM 7f:5m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.64256 Success
Serpina1fem1(IMPC)J JAX Light-Dark Test / Side changes HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.42076 Success
Serpina1fem1(IMPC)J JAX Combined SHIRPA and Dysmorphology / Contact righting HOM 8f:7m Fisher Exact Test framework 1.0000 Success
Serpina1fem1(IMPC)J JAX Grip Strength / Forelimb and hindlimb grip strength normalised against body weight HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.12645 Success
Serpina1fem1(IMPC)J JAX Hole-board Exploration / Total holepokes HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.58049 Success
Serpina1fem1(IMPC)J JAX Open Field / Distance travelled - total HOM 7f:5m Mixed Model framework, linear mixed-effects model, equation withWeight 0.22673 Success
Serpina1fem1(IMPC)J JAX Open Field / Number of rears - total HOM 7f:5m Mixed Model framework, linear mixed-effects model, equation withWeight 0.43937 Success
Serpina1fem1(IMPC)J JAX Combined SHIRPA and Dysmorphology / Unexpected behaviors HOM 8f:7m Fisher Exact Test framework 1.0000 Success
Serpina1fem1(IMPC)J JAX Light-Dark Test / Light side time spent HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.032798 Success
Serpina1fem1(IMPC)J JAX Open Field / Periphery permanence time HOM 7f:5m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.44730 Success
Serpina1fem1(IMPC)J JAX Combined SHIRPA and Dysmorphology / Gait HOM 8f:7m Fisher Exact Test framework 1.0000 Success
Serpina1fem1(IMPC)J JAX Rotarod / Learning slope HOM 8f:6m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.17224 Success
Serpina1fem1(IMPC)J JAX Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI1 HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.42964 Success
Serpina1fem1(IMPC)J JAX Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI3 HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.50343 Success
Serpina1fem1(IMPC)J JAX Open Field / Percentage center time HOM 7f:5m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.44682 Success
Serpina1fem1(IMPC)J JAX Combined SHIRPA and Dysmorphology / Aggression HOM 8f:7m Fisher Exact Test framework 1.0000 Success
Serpina1fem1(IMPC)J JAX Light-Dark Test / Time mobile light side HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.32646 Success
Serpina1fem1(IMPC)J JAX Combined SHIRPA and Dysmorphology / Tremor HOM 8f:7m Fisher Exact Test framework 0.020639 Success
Serpina1fem1(IMPC)J JAX Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI2 HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.59454 Success
Serpina1fem1(IMPC)J JAX Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - S HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0080527 Success
Serpina1fem1(IMPC)J JAX Light-Dark Test / Latency to first transition into dark HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.10882 Success
Serpina1fem1(IMPC)J JAX Rotarod / Learning difference HOM 8f:6m Mixed Model framework, generalized least squares, equation withoutWeight 0.13657 Success
Serpina1fem1(IMPC)J JAX Grip Strength / Forelimb grip strength measurement mean HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.50010 Success
Serpina1fem1(IMPC)J JAX Combined SHIRPA and Dysmorphology / Startle response HOM 8f:7m Fisher Exact Test framework 1.0000 Success
Serpina1fem1(IMPC)J JAX Open Field / Periphery average speed HOM 7f:5m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.38275 Success
Serpina1fem1(IMPC)J JAX Combined SHIRPA and Dysmorphology / Limb grasp HOM 8f:7m Fisher Exact Test framework 0.053552 Success
Serpina1fem1(IMPC)J JAX Eye Morphology / Pupil Light Response HOM 8f:7m Fisher Exact Test framework 1.0000 Success
Serpina1fem1(IMPC)J JAX Open Field / Whole arena average speed HOM 7f:5m Mixed Model framework, linear mixed-effects model, equation withWeight 0.22626 Success
Serpina1fem1(IMPC)J JAX Open Field / Center distance travelled HOM 7f:5m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.21565 Success
Serpina1fem1(IMPC)J JAX Light-Dark Test / Percent time in dark HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.54042 Success
Serpina1fem1(IMPC)J JAX Combined SHIRPA and Dysmorphology / Vocalization HOM 8f:7m Fisher Exact Test framework 1.0000 Success
Serpina1fem1(IMPC)J JAX Open Field / Periphery distance travelled HOM 7f:5m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.48421 Success
Serpina1fem1(IMPC)J JAX Rotarod / Average duration HOM 8f:6m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.98497 Success
Serpina1fem1(IMPC)J JAX Light-Dark Test / Dark side time spent HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.032798 Success
Serpina1fem1(IMPC)J JAX Grip Strength / Forelimb and hindlimb grip strength measurement mean HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.92658 Success

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