Serpina1fem1(IMPC)J
|
JAX
|
Light-Dark Test / Fecal boli
|
HOM
|
9f:10m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.136
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Open Field - centre start / Whole arena average speed
|
HOM
|
7f:5m
|
Linear Mixed Model framework, LME, not including Weight
|
0.151
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Hole-board Exploration / Holepoke sequence
|
HOM
|
308f:306m
|
|
|
NotProcessed |
Serpina1fem1(IMPC)J
|
JAX
|
Open Field - centre start / Distance travelled
|
HOM
|
36f:32m
|
|
|
NotProcessed |
Serpina1fem1(IMPC)J
|
JAX
|
Grip Strength / Forelimb and hindlimb grip strength measurement mean
|
HOM
|
9f:10m
|
Linear Mixed Model framework, LME, including Weight
|
0.00489
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Open Field - centre start / Center distance travelled
|
HOM
|
9f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.0437
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Combined SHIRPA and Dysmorphology / Activity (body position)
|
HOM
|
8f:7m
|
Fisher Exact Test framework
|
0.0535
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Combined SHIRPA and Dysmorphology / Head bobbing
|
HOM
|
8f:7m
|
|
|
NotProcessed |
Serpina1fem1(IMPC)J
|
JAX
|
Open Field - centre start / Periphery average speed
|
HOM
|
9f:8m
|
Linear Model Using Generalized Least Squares framework, GLS, including Weight
|
0.0906
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP1
|
HOM
|
8f:7m
|
|
|
NotProcessed |
Serpina1fem1(IMPC)J
|
JAX
|
Grip Strength / Forelimb grip strength measurement mean
|
HOM
|
9f:10m
|
Linear Mixed Model framework, LME, including Weight
|
0.0442
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Light-Dark Test / Percent time in light
|
HOM
|
8f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.378
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Open Field - centre start / Center average speed
|
HOM
|
7f:5m
|
Linear Mixed Model framework, LME, not including Weight
|
0.591
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Combined SHIRPA and Dysmorphology / Trunk curl
|
HOM
|
8f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Open Field - centre start / Percentage center time
|
HOM
|
9f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.765
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Open Field - centre start / Center permanence time
|
HOM
|
7f:5m
|
Linear Mixed Model framework, LME, not including Weight
|
0.113
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Light-Dark Test / Side changes
|
HOM
|
8f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.444
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Hole-board Exploration / Total holepokes
|
HOM
|
8f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.692
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Light-Dark Test / Time mobile dark side
|
HOM
|
9f:10m
|
Linear Mixed Model framework, LME, not including Weight
|
0.00282
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Combined SHIRPA and Dysmorphology / Unexpected behaviors
|
HOM
|
8f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP2
|
HOM
|
8f:7m
|
|
|
NotProcessed |
Serpina1fem1(IMPC)J
|
JAX
|
Light-Dark Test / Dark side time spent
|
HOM
|
9f:10m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.811
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Open Field - centre start / Number of Rears
|
HOM
|
36f:32m
|
|
|
NotProcessed |
Serpina1fem1(IMPC)J
|
JAX
|
Grip Strength / Forelimb grip strength measurement
|
HOM
|
27f:30m
|
|
|
NotProcessed |
Serpina1fem1(IMPC)J
|
JAX
|
Light-Dark Test / Light side time spent
|
HOM
|
8f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0184
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Open Field - centre start / Periphery distance travelled
|
HOM
|
7f:5m
|
Linear Mixed Model framework, LME, not including Weight
|
0.370
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Grip Strength / Forelimb grip strength normalised against body weight
|
HOM
|
9f:10m
|
Linear Mixed Model framework, LME, not including Weight
|
0.000145
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Open Field - centre start / Whole arena resting time
|
HOM
|
7f:5m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0728
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Open Field - centre start / Center permanence time
|
HOM
|
9f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.765
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Combined SHIRPA and Dysmorphology / Aggression
|
HOM
|
8f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Open Field - centre start / Number of Rears
|
HOM
|
28f:20m
|
|
|
NotProcessed |
Serpina1fem1(IMPC)J
|
JAX
|
Light-Dark Test / Time mobile light side
|
HOM
|
8f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.539
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Light-Dark Test / Time mobile light side
|
HOM
|
9f:10m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0206
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Open Field - centre start / Distance travelled - total
|
HOM
|
9f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.0331
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Grip Strength / Forelimb grip strength measurement mean
|
HOM
|
8f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.970
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Combined SHIRPA and Dysmorphology / Startle response
|
HOM
|
8f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Open Field - centre start / Percentage center time
|
HOM
|
7f:5m
|
Linear Mixed Model framework, LME, not including Weight
|
0.113
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Grip Strength / Forelimb and hindlimb grip strength normalised against body weight
|
HOM
|
9f:10m
|
Linear Mixed Model framework, LME, not including Weight
|
0.000442
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - BN
|
HOM
|
8f:7m
|
|
|
NotProcessed |
Serpina1fem1(IMPC)J
|
JAX
|
Open Field - centre start / Distance travelled
|
HOM
|
28f:20m
|
|
|
NotProcessed |
Serpina1fem1(IMPC)J
|
JAX
|
Open Field - centre start / Center average speed
|
HOM
|
9f:8m
|
Linear Model Using Generalized Least Squares framework, GLS, including Weight
|
0.000495
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Combined SHIRPA and Dysmorphology / Vocalization
|
HOM
|
8f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP3_S
|
HOM
|
8f:7m
|
|
|
NotProcessed |
Serpina1fem1(IMPC)J
|
JAX
|
Light-Dark Test / Light side time spent
|
HOM
|
9f:10m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.811
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Light-Dark Test / Dark side time spent
|
HOM
|
8f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0184
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Open Field - centre start / Number of rears - total
|
HOM
|
9f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.0570
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Grip Strength / Forelimb and hindlimb grip strength measurement mean
|
HOM
|
8f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.834
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Light-Dark Test / Side changes
|
HOM
|
9f:9m
|
Linear Mixed Model framework, LME, not including Weight
|
0.296
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Open Field - centre start / Number of rears - total
|
HOM
|
7f:5m
|
Linear Mixed Model framework, LME, including Weight
|
0.709
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Grip Strength / Forelimb grip strength measurement
|
HOM
|
24f:21m
|
|
|
NotProcessed |
Serpina1fem1(IMPC)J
|
JAX
|
Rotarod / Latency to fall
|
HOM
|
40f:30m
|
|
|
NotProcessed |
Serpina1fem1(IMPC)J
|
JAX
|
Grip Strength / Forelimb grip strength normalised against body weight
|
HOM
|
8f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.354
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Combined SHIRPA and Dysmorphology / Locomotor activity
|
HOM
|
8f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.00134
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Eye Morphology / Optic Disc
|
HOM
|
8f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Combined SHIRPA and Dysmorphology / Tail elevation
|
HOM
|
8f:7m
|
|
|
NotProcessed |
Serpina1fem1(IMPC)J
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP2_S
|
HOM
|
8f:7m
|
|
|
NotProcessed |
Serpina1fem1(IMPC)J
|
JAX
|
Open Field - centre start / Periphery average speed
|
HOM
|
7f:5m
|
Linear Mixed Model framework, LME, not including Weight
|
0.187
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Light-Dark Test / Time mobile dark side
|
HOM
|
8f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.682
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Light-Dark Test / Fecal boli
|
HOM
|
8f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.485
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Open Field - centre start / Whole arena average speed
|
HOM
|
9f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.0333
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Open Field - centre start / Periphery distance travelled
|
HOM
|
9f:8m
|
Linear Model Using Generalized Least Squares framework, GLS, including Weight
|
0.760
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Combined SHIRPA and Dysmorphology / Contact righting
|
HOM
|
8f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Grip Strength / Forelimb and hindlimb grip strength normalised against body weight
|
HOM
|
8f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.115
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Grip Strength / Forelimb and hindlimb grip strength measurement
|
HOM
|
24f:21m
|
|
|
NotProcessed |
Serpina1fem1(IMPC)J
|
JAX
|
Open Field - centre start / Distance travelled - total
|
HOM
|
7f:5m
|
Linear Mixed Model framework, LME, not including Weight
|
0.151
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Light-Dark Test / Percent time in light
|
HOM
|
9f:10m
|
Linear Mixed Model framework, LME, not including Weight
|
0.586
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP1_S
|
HOM
|
8f:7m
|
|
|
NotProcessed |
Serpina1fem1(IMPC)J
|
JAX
|
Open Field - centre start / Periphery permanence time
|
HOM
|
7f:5m
|
Linear Mixed Model framework, LME, not including Weight
|
0.113
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Combined SHIRPA and Dysmorphology / Gait
|
HOM
|
8f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Rotarod / Learning slope
|
HOM
|
8f:6m
|
Linear Mixed Model framework, LME, not including Weight
|
0.157
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI1
|
HOM
|
8f:7m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.418
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI3
|
HOM
|
8f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.664
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Light-Dark Test / Percent time in dark
|
HOM
|
9f:10m
|
Linear Mixed Model framework, LME, not including Weight
|
0.586
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Grip Strength / Forelimb and hindlimb grip strength measurement
|
HOM
|
27f:30m
|
|
|
NotProcessed |
Serpina1fem1(IMPC)J
|
JAX
|
Open Field - centre start / Whole arena resting time
|
HOM
|
9f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.212
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Combined SHIRPA and Dysmorphology / Tremor
|
HOM
|
8f:7m
|
Fisher Exact Test framework
|
0.0197
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Hole-board Exploration / Total holepokes
|
HOM
|
9f:10m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0187
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI2
|
HOM
|
8f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.409
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Light-Dark Test / Latency to first transition into dark
|
HOM
|
8f:7m
|
Linear Model Using Generalized Least Squares framework, GLS, including Weight
|
0.00616
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - S
|
HOM
|
8f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0310
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Rotarod / Learning difference
|
HOM
|
8f:6m
|
Linear Model Using Generalized Least Squares framework, GLS, including Weight
|
0.0987
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Hole-board Exploration / Holepoke sequence
|
HOM
|
258f:221m
|
|
|
NotProcessed |
Serpina1fem1(IMPC)J
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP3
|
HOM
|
8f:7m
|
|
|
NotProcessed |
Serpina1fem1(IMPC)J
|
JAX
|
Combined SHIRPA and Dysmorphology / Limb grasp
|
HOM
|
8f:7m
|
Fisher Exact Test framework
|
0.0456
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Eye Morphology / Pupil Light Response
|
HOM
|
8f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Light-Dark Test / Latency to first transition into dark
|
HOM
|
9f:10m
|
Linear Mixed Model framework, LME, not including Weight
|
0.976
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Combined SHIRPA and Dysmorphology / Transfer arousal
|
HOM
|
8f:7m
|
|
|
NotProcessed |
Serpina1fem1(IMPC)J
|
JAX
|
Light-Dark Test / Percent time in dark
|
HOM
|
8f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.378
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Open Field - centre start / Periphery permanence time
|
HOM
|
9f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.764
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Rotarod / Average duration
|
HOM
|
8f:6m
|
Linear Mixed Model framework, LME, not including Weight
|
0.885
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Open Field - centre start / Center distance travelled
|
HOM
|
7f:5m
|
Linear Mixed Model framework, LME, including Weight
|
0.173
|
Successful |