Serpina1fem1(IMPC)J
|
JAX
|
Combined SHIRPA and Dysmorphology / Forelimb digit - size
|
HOM
|
8f:7m
|
|
|
NotProcessed |
Serpina1fem1(IMPC)J
|
JAX
|
Combined SHIRPA and Dysmorphology / Tail - thickness
|
HOM
|
8f:7m
|
|
|
NotProcessed |
Serpina1fem1(IMPC)J
|
JAX
|
Clinical Chemistry / Alanine aminotransferase
|
HOM
|
5f:5m
|
Linear Mixed Model framework, LME, not including Weight
|
0.738
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Hole-board Exploration / Holepoke sequence
|
HOM
|
308f:306m
|
|
|
NotProcessed |
Serpina1fem1(IMPC)J
|
JAX
|
Combined SHIRPA and Dysmorphology / Coat - hair distribution - back
|
HOM
|
8f:7m
|
|
|
NotProcessed |
Serpina1fem1(IMPC)J
|
JAX
|
Open Field - centre start / Center distance travelled
|
HOM
|
9f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.0437
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Eye Morphology / Bulging eye
|
HOM
|
8f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Combined SHIRPA and Dysmorphology / Forelimb nail - shape
|
HOM
|
8f:7m
|
|
|
NotProcessed |
Serpina1fem1(IMPC)J
|
JAX
|
Electrocardiogram (ECG) / RR
|
HOM
|
8f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.308
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Combined SHIRPA and Dysmorphology / Skin texture - whole body
|
HOM
|
8f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Combined SHIRPA and Dysmorphology / Trunk curl
|
HOM
|
8f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Eye Morphology / Iris/Pupil
|
HOM
|
8f:7m
|
Fisher Exact Test framework
|
0.243
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Open Field - centre start / Percentage center time
|
HOM
|
9f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.765
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Clinical Chemistry / Triglycerides
|
HOM
|
7f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.0641
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Hematology / Mean cell hemoglobin concentration
|
HOM
|
1f:m
|
|
|
NotProcessed |
Serpina1fem1(IMPC)J
|
JAX
|
Hematology / Mean cell hemoglobin concentration
|
HOM
|
5f:5m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0995
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Clinical Chemistry / Calcium
|
HOM
|
7f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.0376
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP2
|
HOM
|
8f:7m
|
|
|
NotProcessed |
Serpina1fem1(IMPC)J
|
JAX
|
Open Field - centre start / Number of Rears
|
HOM
|
36f:32m
|
|
|
NotProcessed |
Serpina1fem1(IMPC)J
|
JAX
|
Heart Weight / Heart weight normalised against body weight
|
HOM
|
8f:6m
|
|
|
NotProcessed |
Serpina1fem1(IMPC)J
|
JAX
|
Body Composition (DEXA lean/fat) / Lean mass
|
HOM
|
8f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.670
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Electrocardiogram (ECG) / ST
|
HOM
|
5f:5m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.782
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Eye Morphology / Corneal deposits
|
HOM
|
8f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Auditory Brain Stem Response / 6kHz-evoked ABR Threshold
|
HOM
|
3f:4m
|
Reference Range Plus Test framework; quantile = 0.95 (Tails probability = 0.025)
|
0.0495
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Clinical Chemistry / Creatinine
|
HOM
|
7f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.770
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Open Field - centre start / Number of Rears
|
HOM
|
28f:20m
|
|
|
NotProcessed |
Serpina1fem1(IMPC)J
|
JAX
|
Body Composition (DEXA lean/fat) / Body length
|
HOM
|
8f:7m
|
|
|
NotProcessed |
Serpina1fem1(IMPC)J
|
JAX
|
Light-Dark Test / Time mobile light side
|
HOM
|
9f:10m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0206
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Combined SHIRPA and Dysmorphology / Vibrissae - presence
|
HOM
|
8f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Urinalysis / Magnesium
|
HOM
|
8f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.713
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Gross Pathology and Tissue Collection / Thyroid
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Gross Pathology and Tissue Collection / Thyroid
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Gross Pathology and Tissue Collection / Thyroid
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Gross Pathology and Tissue Collection / Thyroid
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Open Field - centre start / Percentage center time
|
HOM
|
7f:5m
|
Linear Mixed Model framework, LME, not including Weight
|
0.113
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Grip Strength / Forelimb and hindlimb grip strength normalised against body weight
|
HOM
|
9f:10m
|
Linear Mixed Model framework, LME, not including Weight
|
0.000442
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Combined SHIRPA and Dysmorphology / Lower teeth appearance
|
HOM
|
8f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Eye Morphology / Lens Opacity
|
HOM
|
8f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Combined SHIRPA and Dysmorphology / Skin texture - back paws
|
HOM
|
8f:7m
|
|
|
NotProcessed |
Serpina1fem1(IMPC)J
|
JAX
|
Electrocardiogram (ECG) / Number of signals
|
HOM
|
5f:5m
|
|
|
NotProcessed |
Serpina1fem1(IMPC)J
|
JAX
|
Hematology / Hematocrit
|
HOM
|
7f:8m
|
Linear Model Using Generalized Least Squares framework, GLS, including Weight
|
0.0875
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Combined SHIRPA and Dysmorphology / Forelimbs - shape
|
HOM
|
8f:7m
|
|
|
NotProcessed |
Serpina1fem1(IMPC)J
|
JAX
|
Eye Morphology / Retinal Structure
|
HOM
|
8f:7m
|
|
|
NotProcessed |
Serpina1fem1(IMPC)J
|
JAX
|
Heart Weight / Heart weight normalised against body weight
|
HOM
|
9f:9m
|
|
|
NotProcessed |
Serpina1fem1(IMPC)J
|
JAX
|
Light-Dark Test / Dark side time spent
|
HOM
|
8f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0184
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Heart Weight / Heart weight
|
HOM
|
9f:9m
|
Linear Mixed Model framework, LME, including Weight
|
0.457
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Eye Morphology / Retina (combined)
|
HOM
|
8f:7m
|
Fisher Exact Test framework
|
0.751
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Body Composition (DEXA lean/fat) / BMC/Body weight
|
HOM
|
8f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.703
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Heart Weight / Body weight
|
HOM
|
8f:6m
|
|
|
NotProcessed |
Serpina1fem1(IMPC)J
|
JAX
|
Gross Pathology and Tissue Collection / Spleen
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Gross Pathology and Tissue Collection / Spleen
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Gross Pathology and Tissue Collection / Spleen
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Gross Pathology and Tissue Collection / Spleen
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Clinical Chemistry / Phosphorus
|
HOM
|
7f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.583
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Clinical Chemistry / Calcium
|
HOM
|
5f:5m
|
Linear Mixed Model framework, LME, not including Weight
|
0.646
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Combined SHIRPA and Dysmorphology / Tail elevation
|
HOM
|
8f:7m
|
|
|
NotProcessed |
Serpina1fem1(IMPC)J
|
JAX
|
Electrocardiogram (ECG) / Mean SR amplitude
|
HOM
|
5f:5m
|
|
|
NotProcessed |
Serpina1fem1(IMPC)J
|
JAX
|
Open Field - centre start / Periphery distance travelled
|
HOM
|
9f:8m
|
Linear Model Using Generalized Least Squares framework, GLS, including Weight
|
0.760
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Combined SHIRPA and Dysmorphology / Contact righting
|
HOM
|
8f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Hematology / Hematocrit
|
HOM
|
1f:m
|
|
|
NotProcessed |
Serpina1fem1(IMPC)J
|
JAX
|
Hematology / Hematocrit
|
HOM
|
5f:5m
|
Linear Mixed Model framework, LME, not including Weight
|
0.410
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Combined SHIRPA and Dysmorphology / Skin color - ear
|
HOM
|
8f:7m
|
|
|
NotProcessed |
Serpina1fem1(IMPC)J
|
JAX
|
Electrocardiogram (ECG) / Number of signals
|
HOM
|
8f:7m
|
|
|
NotProcessed |
Serpina1fem1(IMPC)J
|
JAX
|
Grip Strength / Forelimb and hindlimb grip strength normalised against body weight
|
HOM
|
8f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.115
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Gross Pathology and Tissue Collection / Esophagus
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Gross Pathology and Tissue Collection / Esophagus
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Gross Pathology and Tissue Collection / Esophagus
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Gross Pathology and Tissue Collection / Esophagus
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Combined SHIRPA and Dysmorphology / Hindlimb nail - number
|
HOM
|
8f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Combined SHIRPA and Dysmorphology / Coat - hair texture / appearance - head
|
HOM
|
8f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Grip Strength / Body weight
|
HOM
|
8f:7m
|
|
|
NotProcessed |
Serpina1fem1(IMPC)J
|
JAX
|
Electrocardiogram (ECG) / RR
|
HOM
|
5f:5m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.0610
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Intraperitoneal glucose tolerance test (IPGTT) / Area under glucose response curve
|
HOM
|
8f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.970
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Combined SHIRPA and Dysmorphology / Coat - color - abdomen
|
HOM
|
8f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP1_S
|
HOM
|
8f:7m
|
|
|
NotProcessed |
Serpina1fem1(IMPC)J
|
JAX
|
Clinical Chemistry / Alanine aminotransferase
|
HOM
|
7f:8m
|
Linear Model Using Generalized Least Squares framework, GLS, including Weight
|
0.375
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Rotarod / Learning slope
|
HOM
|
8f:6m
|
Linear Mixed Model framework, LME, not including Weight
|
0.157
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Eye Morphology / Pupil Dilation
|
HOM
|
8f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Body Composition (DEXA lean/fat) / Fat mass
|
HOM
|
8f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.383
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Clinical Chemistry / Potassium
|
HOM
|
5f:5m
|
Linear Mixed Model framework, LME, not including Weight
|
0.652
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI3
|
HOM
|
8f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.664
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Auditory Brain Stem Response / 30kHz-evoked ABR Threshold
|
HOM
|
3f:4m
|
Reference Range Plus Test framework; quantile = 0.95 (Tails probability = 0.025)
|
0.0314
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Clinical Chemistry / Phosphorus
|
HOM
|
5f:5m
|
Linear Mixed Model framework, LME, including Weight
|
0.762
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Combined SHIRPA and Dysmorphology / Hindpaw - shape
|
HOM
|
8f:7m
|
|
|
NotProcessed |
Serpina1fem1(IMPC)J
|
JAX
|
Combined SHIRPA and Dysmorphology / Tremor
|
HOM
|
8f:7m
|
Fisher Exact Test framework
|
0.0197
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Hole-board Exploration / Total holepokes
|
HOM
|
9f:10m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0187
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Combined SHIRPA and Dysmorphology / Genitalia - morphology
|
HOM
|
8f:7m
|
|
|
NotProcessed |
Serpina1fem1(IMPC)J
|
JAX
|
Viability Primary Screen / Viability Outcome
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Gross Pathology and Tissue Collection / Brain
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Gross Pathology and Tissue Collection / Brain
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Gross Pathology and Tissue Collection / Brain
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Gross Pathology and Tissue Collection / Brain
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Gross Pathology and Tissue Collection / Lymph node
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Gross Pathology and Tissue Collection / Lymph node
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Gross Pathology and Tissue Collection / Lymph node
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Gross Pathology and Tissue Collection / Lymph node
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Hematology / Mean cell hemoglobin concentration
|
HOM
|
7f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.0620
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Combined SHIRPA and Dysmorphology / Head morphology
|
HOM
|
8f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Electrocardiogram (ECG) / ST
|
HOM
|
8f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.452
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Combined SHIRPA and Dysmorphology / Upper teeth appearance
|
HOM
|
8f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Light-Dark Test / Latency to first transition into dark
|
HOM
|
9f:10m
|
Linear Mixed Model framework, LME, not including Weight
|
0.976
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Intraperitoneal glucose tolerance test (IPGTT) / Body Weight
|
HOM
|
8f:7m
|
|
|
NotProcessed |
Serpina1fem1(IMPC)J
|
JAX
|
Auditory Brain Stem Response / 18kHz-evoked ABR Threshold
|
HOM
|
3f:4m
|
Reference Range Plus Test framework; quantile = 0.95 (Tails probability = 0.025)
|
0.00528
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Light-Dark Test / Percent time in dark
|
HOM
|
8f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.378
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Eye Morphology / Corneal vascularization
|
HOM
|
8f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Electrocardiogram (ECG) / Mean SR amplitude
|
HOM
|
8f:7m
|
|
|
NotProcessed |
Serpina1fem1(IMPC)J
|
JAX
|
Eye Morphology / Retinal Blood Vessels Pattern
|
HOM
|
8f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Clinical Chemistry / Triglycerides
|
HOM
|
5f:4m
|
Linear Mixed Model framework, LME, including Weight
|
0.743
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Grip Strength / Body weight
|
HOM
|
9f:10m
|
|
|
NotProcessed |
Serpina1fem1(IMPC)J
|
JAX
|
Body Weight / Body weight
|
HOM
|
27f:29m
|
|
|
NotProcessed |
Serpina1fem1(IMPC)J
|
JAX
|
Light-Dark Test / Fecal boli
|
HOM
|
9f:10m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.136
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Open Field - centre start / Whole arena average speed
|
HOM
|
7f:5m
|
Linear Mixed Model framework, LME, not including Weight
|
0.151
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Body Weight / Body weight curve
|
HOM
|
335f:320m
|
|
|
NotProcessed |
Serpina1fem1(IMPC)J
|
JAX
|
Open Field - centre start / Distance travelled
|
HOM
|
36f:32m
|
|
|
NotProcessed |
Serpina1fem1(IMPC)J
|
JAX
|
Electrocardiogram (ECG) / PQ
|
HOM
|
8f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.00428
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Body Composition (DEXA lean/fat) / Bone Area
|
HOM
|
8f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.309
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Hematology / White blood cell count
|
HOM
|
7f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.496
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Hematology / Platelet count
|
HOM
|
1f:m
|
|
|
NotProcessed |
Serpina1fem1(IMPC)J
|
JAX
|
Hematology / Platelet count
|
HOM
|
5f:5m
|
Linear Mixed Model framework, LME, not including Weight
|
0.903
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Combined SHIRPA and Dysmorphology / Activity (body position)
|
HOM
|
8f:7m
|
Fisher Exact Test framework
|
0.0535
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP1
|
HOM
|
8f:7m
|
|
|
NotProcessed |
Serpina1fem1(IMPC)J
|
JAX
|
Gross Pathology and Tissue Collection / Liver
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Gross Pathology and Tissue Collection / Liver
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Gross Pathology and Tissue Collection / Liver
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Gross Pathology and Tissue Collection / Liver
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Combined SHIRPA and Dysmorphology / Hindlimb digit - size
|
HOM
|
8f:7m
|
|
|
NotProcessed |
Serpina1fem1(IMPC)J
|
JAX
|
Electrocardiogram (ECG) / QRS
|
HOM
|
5f:5m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.327
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Open Field - centre start / Center average speed
|
HOM
|
7f:5m
|
Linear Mixed Model framework, LME, not including Weight
|
0.591
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Clinical Chemistry / Total bilirubin
|
HOM
|
7f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.100
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Gross Pathology and Tissue Collection / Thymus
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Gross Pathology and Tissue Collection / Thymus
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Gross Pathology and Tissue Collection / Thymus
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Gross Pathology and Tissue Collection / Thymus
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Combined SHIRPA and Dysmorphology / Skin texture - snout
|
HOM
|
8f:7m
|
|
|
NotProcessed |
Serpina1fem1(IMPC)J
|
JAX
|
Clinical Chemistry / Total protein
|
HOM
|
2f:4m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0881
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Eye Morphology / Pupil Position
|
HOM
|
8f:7m
|
Fisher Exact Test framework
|
0.259
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Combined SHIRPA and Dysmorphology / Hindlimbs - position
|
HOM
|
8f:7m
|
|
|
NotProcessed |
Serpina1fem1(IMPC)J
|
JAX
|
Body Composition (DEXA lean/fat) / Fat/Body weight
|
HOM
|
8f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.193
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Clinical Chemistry / Glucose
|
HOM
|
7f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.00326
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Eye Morphology / Eyelid closure
|
HOM
|
8f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Electrocardiogram (ECG) / Mean R amplitude
|
HOM
|
5f:5m
|
|
|
NotProcessed |
Serpina1fem1(IMPC)J
|
JAX
|
Body Composition (DEXA lean/fat) / Bone Mineral Density (excluding skull)
|
HOM
|
8f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.00679
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Light-Dark Test / Time mobile light side
|
HOM
|
8f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.539
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Combined SHIRPA and Dysmorphology / Forelimbs - size
|
HOM
|
8f:7m
|
|
|
NotProcessed |
Serpina1fem1(IMPC)J
|
JAX
|
Electrocardiogram (ECG) / pNN5(6>ms)
|
HOM
|
8f:7m
|
|
|
NotProcessed |
Serpina1fem1(IMPC)J
|
JAX
|
Heart Weight / Body weight
|
HOM
|
9f:9m
|
|
|
NotProcessed |
Serpina1fem1(IMPC)J
|
JAX
|
Combined SHIRPA and Dysmorphology / Tail - morphology
|
HOM
|
8f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Combined SHIRPA and Dysmorphology / Coat - color pattern - abdomen
|
HOM
|
8f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Open Field - centre start / Distance travelled
|
HOM
|
28f:20m
|
|
|
NotProcessed |
Serpina1fem1(IMPC)J
|
JAX
|
Eye Morphology / Iris transilumination
|
HOM
|
8f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Clinical Chemistry / Aspartate aminotransferase
|
HOM
|
5f:5m
|
Linear Mixed Model framework, LME, including Weight
|
0.835
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Combined SHIRPA and Dysmorphology / Hindlimb nail - length
|
HOM
|
8f:7m
|
|
|
NotProcessed |
Serpina1fem1(IMPC)J
|
JAX
|
Combined SHIRPA and Dysmorphology / Vocalization
|
HOM
|
8f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Light-Dark Test / Light side time spent
|
HOM
|
9f:10m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.811
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Urinalysis / Albumin to Creatinine ratio
|
HOM
|
8f:7m
|
|
|
NotProcessed |
Serpina1fem1(IMPC)J
|
JAX
|
Open Field - centre start / Number of rears - total
|
HOM
|
9f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.0570
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Grip Strength / Forelimb and hindlimb grip strength measurement mean
|
HOM
|
8f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.834
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Hematology / Hemoglobin
|
HOM
|
1f:m
|
|
|
NotProcessed |
Serpina1fem1(IMPC)J
|
JAX
|
Hematology / Hemoglobin
|
HOM
|
5f:5m
|
Linear Mixed Model framework, LME, including Weight
|
0.206
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Light-Dark Test / Side changes
|
HOM
|
9f:9m
|
Linear Mixed Model framework, LME, not including Weight
|
0.296
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Hematology / Mean corpuscular hemoglobin
|
HOM
|
7f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.00374
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Combined SHIRPA and Dysmorphology / Teeth presence
|
HOM
|
8f:7m
|
|
|
NotProcessed |
Serpina1fem1(IMPC)J
|
JAX
|
Eye Morphology / Vitreous
|
HOM
|
8f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Electrocardiogram (ECG) / CV
|
HOM
|
5f:5m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.596
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Rotarod / Latency to fall
|
HOM
|
40f:30m
|
|
|
NotProcessed |
Serpina1fem1(IMPC)J
|
JAX
|
Eye Morphology / Lens
|
HOM
|
8f:7m
|
Fisher Exact Test framework
|
0.149
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Electrocardiogram (ECG) / QTc
|
HOM
|
8f:7m
|
|
|
NotProcessed |
Serpina1fem1(IMPC)J
|
JAX
|
Grip Strength / Forelimb grip strength normalised against body weight
|
HOM
|
8f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.354
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Combined SHIRPA and Dysmorphology / Head size
|
HOM
|
8f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Eye Morphology / Optic Disc
|
HOM
|
8f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Combined SHIRPA and Dysmorphology / Coat - color pattern - back
|
HOM
|
8f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Open Field - centre start / Whole arena average speed
|
HOM
|
9f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.0333
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Eye Morphology / Narrow eye opening
|
HOM
|
8f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Clinical Chemistry / Sodium
|
HOM
|
5f:5m
|
Linear Mixed Model framework, LME, including Weight
|
0.932
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Body Composition (DEXA lean/fat) / Lean/Body weight
|
HOM
|
8f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.489
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Combined SHIRPA and Dysmorphology / Forepaw - shape
|
HOM
|
8f:7m
|
|
|
NotProcessed |
Serpina1fem1(IMPC)J
|
JAX
|
Heart Weight / Heart weight
|
HOM
|
8f:6m
|
Linear Mixed Model framework, LME, including Weight
|
0.109
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Body Composition (DEXA lean/fat) / Bone Mineral Content (excluding skull)
|
HOM
|
8f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.599
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Open Field - centre start / Periphery permanence time
|
HOM
|
7f:5m
|
Linear Mixed Model framework, LME, not including Weight
|
0.113
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Combined SHIRPA and Dysmorphology / Skin color - snout
|
HOM
|
8f:7m
|
|
|
NotProcessed |
Serpina1fem1(IMPC)J
|
JAX
|
Gross Pathology and Tissue Collection / Skin
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Gross Pathology and Tissue Collection / Skin
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Gross Pathology and Tissue Collection / Skin
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Gross Pathology and Tissue Collection / Skin
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Combined SHIRPA and Dysmorphology / Coat - hair texture / appearance - back
|
HOM
|
8f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Grip Strength / Forelimb and hindlimb grip strength measurement
|
HOM
|
27f:30m
|
|
|
NotProcessed |
Serpina1fem1(IMPC)J
|
JAX
|
Clinical Chemistry / HDL-cholesterol
|
HOM
|
5f:5m
|
Linear Mixed Model framework, LME, including Weight
|
0.763
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Gross Pathology and Tissue Collection / Lung
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Gross Pathology and Tissue Collection / Lung
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Gross Pathology and Tissue Collection / Lung
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Gross Pathology and Tissue Collection / Lung
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Eye Morphology / Persistence of hyaloid vascular system
|
HOM
|
8f:7m
|
Fisher Exact Test framework
|
0.485
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI2
|
HOM
|
8f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.409
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Light-Dark Test / Latency to first transition into dark
|
HOM
|
8f:7m
|
Linear Model Using Generalized Least Squares framework, GLS, including Weight
|
0.00616
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - S
|
HOM
|
8f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0310
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Eye Morphology / Pupil Shape
|
HOM
|
8f:7m
|
Fisher Exact Test framework
|
0.122
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Clinical Chemistry / Alkaline phosphatase
|
HOM
|
7f:8m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.138
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Electrocardiogram (ECG) / QTc Dispersion
|
HOM
|
8f:7m
|
|
|
NotProcessed |
Serpina1fem1(IMPC)J
|
JAX
|
Intraperitoneal glucose tolerance test (IPGTT) / Blood glucose concentration
|
HOM
|
40f:35m
|
|
|
NotProcessed |
Serpina1fem1(IMPC)J
|
JAX
|
Eye Morphology / Eye
|
HOM
|
8f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Fertility of Homozygous Knock-out Mice / Gross Findings Male
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Hole-board Exploration / Holepoke sequence
|
HOM
|
258f:221m
|
|
|
NotProcessed |
Serpina1fem1(IMPC)J
|
JAX
|
Combined SHIRPA and Dysmorphology / Transfer arousal
|
HOM
|
8f:7m
|
|
|
NotProcessed |
Serpina1fem1(IMPC)J
|
JAX
|
Gross Pathology and Tissue Collection / Pancreas
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Gross Pathology and Tissue Collection / Pancreas
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Gross Pathology and Tissue Collection / Pancreas
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Gross Pathology and Tissue Collection / Pancreas
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Combined SHIRPA and Dysmorphology / Mouth morphology
|
HOM
|
8f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Clinical Chemistry / Albumin
|
HOM
|
7f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.323
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Combined SHIRPA and Dysmorphology / Head bobbing
|
HOM
|
8f:7m
|
|
|
NotProcessed |
Serpina1fem1(IMPC)J
|
JAX
|
Grip Strength / Forelimb grip strength measurement mean
|
HOM
|
9f:10m
|
Linear Mixed Model framework, LME, including Weight
|
0.0442
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Light-Dark Test / Percent time in light
|
HOM
|
8f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.378
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Gross Pathology and Tissue Collection / Spinal cord
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Gross Pathology and Tissue Collection / Spinal cord
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Gross Pathology and Tissue Collection / Spinal cord
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Gross Pathology and Tissue Collection / Spinal cord
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Body Composition (DEXA lean/fat) / Lean/Body weight
|
HOM
|
8f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.548
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Open Field - centre start / Center permanence time
|
HOM
|
7f:5m
|
Linear Mixed Model framework, LME, not including Weight
|
0.113
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Electrocardiogram (ECG) / rMSSD
|
HOM
|
8f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.883
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Combined SHIRPA and Dysmorphology / Skin texture - ear
|
HOM
|
8f:7m
|
|
|
NotProcessed |
Serpina1fem1(IMPC)J
|
JAX
|
Eye Morphology / Retina
|
HOM
|
8f:7m
|
|
|
NotProcessed |
Serpina1fem1(IMPC)J
|
JAX
|
Body Composition (DEXA lean/fat) / Body weight
|
HOM
|
8f:7m
|
|
|
NotProcessed |
Serpina1fem1(IMPC)J
|
JAX
|
Light-Dark Test / Time mobile dark side
|
HOM
|
9f:10m
|
Linear Mixed Model framework, LME, not including Weight
|
0.00282
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Combined SHIRPA and Dysmorphology / Snout size
|
HOM
|
8f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Open Field - centre start / Whole arena permanence
|
HOM
|
7f:5m
|
|
|
NotProcessed |
Serpina1fem1(IMPC)J
|
JAX
|
Light-Dark Test / Transition
|
HOM
|
8f:7m
|
|
|
NotProcessed |
Serpina1fem1(IMPC)J
|
JAX
|
Electrocardiogram (ECG) / PR
|
HOM
|
8f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.0303
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Hematology / Red blood cell count
|
HOM
|
7f:8m
|
Linear Model Using Generalized Least Squares framework, GLS, including Weight
|
0.0626
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Eye Morphology / Synechia
|
HOM
|
8f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Clinical Chemistry / Iron
|
HOM
|
5f:5m
|
Linear Mixed Model framework, LME, not including Weight
|
0.172
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Auditory Brain Stem Response / 24kHz-evoked ABR Threshold
|
HOM
|
3f:4m
|
Reference Range Plus Test framework; quantile = 0.95 (Tails probability = 0.025)
|
0.0462
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Clinical Chemistry / Total cholesterol
|
HOM
|
5f:5m
|
Linear Mixed Model framework, LME, including Weight
|
0.314
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Grip Strength / Forelimb grip strength measurement
|
HOM
|
27f:30m
|
|
|
NotProcessed |
Serpina1fem1(IMPC)J
|
JAX
|
Light-Dark Test / Light side time spent
|
HOM
|
8f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0184
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Combined SHIRPA and Dysmorphology / Genitalia - size
|
HOM
|
8f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Clinical Chemistry / Cholesterol ratio
|
HOM
|
5f:5m
|
Linear Mixed Model framework, LME, not including Weight
|
0.400
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Clinical Chemistry / Albumin
|
HOM
|
5f:5m
|
Linear Mixed Model framework, LME, including Weight
|
0.986
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Combined SHIRPA and Dysmorphology / Forelimb nail - length
|
HOM
|
8f:7m
|
|
|
NotProcessed |
Serpina1fem1(IMPC)J
|
JAX
|
Body Weight / Body weight
|
HOM
|
114f:116m
|
|
|
NotProcessed |
Serpina1fem1(IMPC)J
|
JAX
|
Electrocardiogram (ECG) / HR
|
HOM
|
8f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.241
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Intraperitoneal glucose tolerance test (IPGTT) / Initial response to glucose challenge
|
HOM
|
8f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.947
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Open Field - centre start / Center permanence time
|
HOM
|
9f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.765
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Combined SHIRPA and Dysmorphology / Aggression
|
HOM
|
8f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Combined SHIRPA and Dysmorphology / Hindlimbs - shape
|
HOM
|
8f:7m
|
|
|
NotProcessed |
Serpina1fem1(IMPC)J
|
JAX
|
Open Field - centre start / Distance travelled - total
|
HOM
|
9f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.0331
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Grip Strength / Forelimb grip strength measurement mean
|
HOM
|
8f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.970
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Gross Pathology and Tissue Collection / Adrenal gland
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Gross Pathology and Tissue Collection / Adrenal gland
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Gross Pathology and Tissue Collection / Adrenal gland
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Gross Pathology and Tissue Collection / Adrenal gland
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Combined SHIRPA and Dysmorphology / Startle response
|
HOM
|
8f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - BN
|
HOM
|
8f:7m
|
|
|
NotProcessed |
Serpina1fem1(IMPC)J
|
JAX
|
Gross Pathology and Tissue Collection / Urinary bladder
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Gross Pathology and Tissue Collection / Urinary bladder
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Gross Pathology and Tissue Collection / Urinary bladder
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Gross Pathology and Tissue Collection / Urinary bladder
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Electrocardiogram (ECG) / rMSSD
|
HOM
|
5f:5m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.691
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Eye Morphology / Eyelid morphology
|
HOM
|
8f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Hematology / Mean cell volume
|
HOM
|
1f:m
|
|
|
NotProcessed |
Serpina1fem1(IMPC)J
|
JAX
|
Hematology / Mean cell volume
|
HOM
|
5f:5m
|
Linear Mixed Model framework, LME, including Weight
|
0.557
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Gross Pathology and Tissue Collection / Gall bladder
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Gross Pathology and Tissue Collection / Gall bladder
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Gross Pathology and Tissue Collection / Gall bladder
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Gross Pathology and Tissue Collection / Gall bladder
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Combined SHIRPA and Dysmorphology / Coat - color - back
|
HOM
|
8f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Body Composition (DEXA lean/fat) / Bone Mineral Content (excluding skull)
|
HOM
|
8f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.0466
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Combined SHIRPA and Dysmorphology / Forelimb digit - shape
|
HOM
|
8f:7m
|
|
|
NotProcessed |
Serpina1fem1(IMPC)J
|
JAX
|
Clinical Chemistry / Free fatty acids
|
HOM
|
5f:5m
|
Linear Mixed Model framework, LME, including Weight
|
0.578
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Eye Morphology / Cornea
|
HOM
|
8f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Auditory Brain Stem Response / 12kHz-evoked ABR Threshold
|
HOM
|
3f:4m
|
Reference Range Plus Test framework; quantile = 0.95 (Tails probability = 0.025)
|
0.0264
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Electrocardiogram (ECG) / HR
|
HOM
|
5f:5m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.0634
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Open Field - centre start / Number of rears - total
|
HOM
|
7f:5m
|
Linear Mixed Model framework, LME, including Weight
|
0.709
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Combined SHIRPA and Dysmorphology / Hindpaw - size
|
HOM
|
8f:7m
|
|
|
NotProcessed |
Serpina1fem1(IMPC)J
|
JAX
|
Grip Strength / Forelimb grip strength measurement
|
HOM
|
24f:21m
|
|
|
NotProcessed |
Serpina1fem1(IMPC)J
|
JAX
|
Hematology / Mean cell volume
|
HOM
|
7f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.181
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Body Composition (DEXA lean/fat) / Bone Mineral Density (excluding skull)
|
HOM
|
8f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.577
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Combined SHIRPA and Dysmorphology / Upper lip morphology
|
HOM
|
8f:7m
|
|
|
NotProcessed |
Serpina1fem1(IMPC)J
|
JAX
|
Hematology / Red blood cell count
|
HOM
|
1f:m
|
|
|
NotProcessed |
Serpina1fem1(IMPC)J
|
JAX
|
Hematology / Red blood cell count
|
HOM
|
5f:5m
|
Linear Mixed Model framework, LME, not including Weight
|
0.500
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Combined SHIRPA and Dysmorphology / Locomotor activity
|
HOM
|
8f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.00134
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Open Field - centre start / Periphery average speed
|
HOM
|
7f:5m
|
Linear Mixed Model framework, LME, not including Weight
|
0.187
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Urinalysis / Creatinine
|
HOM
|
8f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.622
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Light-Dark Test / Fecal boli
|
HOM
|
8f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.485
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Clinical Chemistry / Urea (Blood Urea Nitrogen - BUN)
|
HOM
|
7f:8m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.658
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Gross Pathology and Tissue Collection / Skeletal muscle
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Gross Pathology and Tissue Collection / Skeletal muscle
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Gross Pathology and Tissue Collection / Skeletal muscle
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Gross Pathology and Tissue Collection / Skeletal muscle
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Combined SHIRPA and Dysmorphology / Skin texture - tail
|
HOM
|
8f:7m
|
|
|
NotProcessed |
Serpina1fem1(IMPC)J
|
JAX
|
Light-Dark Test / Percent time in light
|
HOM
|
9f:10m
|
Linear Mixed Model framework, LME, not including Weight
|
0.586
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Eye Morphology / Iris Pigmentation
|
HOM
|
8f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Combined SHIRPA and Dysmorphology / Vibrissae - appearance
|
HOM
|
8f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Electrocardiogram (ECG) / HRV
|
HOM
|
8f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.475
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI1
|
HOM
|
8f:7m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.418
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Eye Morphology / Retinal Blood Vessels
|
HOM
|
8f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Combined SHIRPA and Dysmorphology / Skin color - back paws
|
HOM
|
8f:7m
|
|
|
NotProcessed |
Serpina1fem1(IMPC)J
|
JAX
|
Electrocardiogram (ECG) / PR
|
HOM
|
5f:5m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.288
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Gross Pathology and Tissue Collection / Large intestine
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Gross Pathology and Tissue Collection / Large intestine
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Gross Pathology and Tissue Collection / Large intestine
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Gross Pathology and Tissue Collection / Large intestine
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Combined SHIRPA and Dysmorphology / Limb grasp
|
HOM
|
8f:7m
|
Fisher Exact Test framework
|
0.0456
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Combined SHIRPA and Dysmorphology / Skin color - whole body
|
HOM
|
8f:7m
|
|
|
NotProcessed |
Serpina1fem1(IMPC)J
|
JAX
|
Clinical Chemistry / Total cholesterol
|
HOM
|
7f:8m
|
Linear Model Using Generalized Least Squares framework, GLS, including Weight
|
0.0616
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Clinical Chemistry / Cholesterol ratio
|
HOM
|
7f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.000507
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Body Composition (DEXA lean/fat) / Fat/Body weight
|
HOM
|
8f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.937
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Combined SHIRPA and Dysmorphology / Coat - hair distribution - abdomen
|
HOM
|
8f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Electrocardiogram (ECG) / HRV
|
HOM
|
5f:5m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.605
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Open Field - centre start / Periphery permanence time
|
HOM
|
9f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.764
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Rotarod / Average duration
|
HOM
|
8f:6m
|
Linear Mixed Model framework, LME, not including Weight
|
0.885
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Open Field - centre start / Whole arena permanence
|
HOM
|
9f:8m
|
|
|
NotProcessed |
Serpina1fem1(IMPC)J
|
JAX
|
Clinical Chemistry / Urea (Blood Urea Nitrogen - BUN)
|
HOM
|
5f:5m
|
Linear Mixed Model framework, LME, not including Weight
|
0.206
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Combined SHIRPA and Dysmorphology / Coat - color pattern - head
|
HOM
|
8f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Electrocardiogram (ECG) / Mean R amplitude
|
HOM
|
8f:7m
|
|
|
NotProcessed |
Serpina1fem1(IMPC)J
|
JAX
|
Combined SHIRPA and Dysmorphology / Genitalia - presence
|
HOM
|
8f:7m
|
|
|
NotProcessed |
Serpina1fem1(IMPC)J
|
JAX
|
Grip Strength / Forelimb and hindlimb grip strength measurement mean
|
HOM
|
9f:10m
|
Linear Mixed Model framework, LME, including Weight
|
0.00489
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Open Field - centre start / Periphery average speed
|
HOM
|
9f:8m
|
Linear Model Using Generalized Least Squares framework, GLS, including Weight
|
0.0906
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Combined SHIRPA and Dysmorphology / Coat - hair distribution - head
|
HOM
|
8f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Clinical Chemistry / HDL-cholesterol
|
HOM
|
7f:8m
|
Linear Model Using Generalized Least Squares framework, GLS, including Weight
|
0.321
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Body Composition (DEXA lean/fat) / Fat mass
|
HOM
|
8f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.878
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Urinalysis / Glucose
|
HOM
|
8f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.167
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Light-Dark Test / Side changes
|
HOM
|
8f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.444
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Eye Morphology / Corneal Sclerization
|
HOM
|
8f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Combined SHIRPA and Dysmorphology / Hindlimb digit - number
|
HOM
|
8f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Clinical Chemistry / Alkaline phosphatase
|
HOM
|
5f:5m
|
Linear Mixed Model framework, LME, including Weight
|
0.200
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Combined SHIRPA and Dysmorphology / Tail - length
|
HOM
|
8f:7m
|
|
|
NotProcessed |
Serpina1fem1(IMPC)J
|
JAX
|
Hole-board Exploration / Total holepokes
|
HOM
|
8f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.692
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Gross Pathology and Tissue Collection / Stomach
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Gross Pathology and Tissue Collection / Stomach
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Gross Pathology and Tissue Collection / Stomach
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Gross Pathology and Tissue Collection / Stomach
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Eye Morphology / Eye Hemorrhage or Blood Presence
|
HOM
|
8f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Combined SHIRPA and Dysmorphology / Hindlimb nail - shape
|
HOM
|
8f:7m
|
|
|
NotProcessed |
Serpina1fem1(IMPC)J
|
JAX
|
Combined SHIRPA and Dysmorphology / Unexpected behaviors
|
HOM
|
8f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Light-Dark Test / Dark side time spent
|
HOM
|
9f:10m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.811
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Open Field - centre start / Periphery distance travelled
|
HOM
|
7f:5m
|
Linear Mixed Model framework, LME, not including Weight
|
0.370
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Combined SHIRPA and Dysmorphology / Hindlimbs - size
|
HOM
|
8f:7m
|
|
|
NotProcessed |
Serpina1fem1(IMPC)J
|
JAX
|
Combined SHIRPA and Dysmorphology / Skin texture - front paws
|
HOM
|
8f:7m
|
|
|
NotProcessed |
Serpina1fem1(IMPC)J
|
JAX
|
Body Composition (DEXA lean/fat) / Bone Area
|
HOM
|
8f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.638
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Body Weight / Body weight
|
HOM
|
142f:127m
|
|
|
NotProcessed |
Serpina1fem1(IMPC)J
|
JAX
|
Grip Strength / Forelimb grip strength normalised against body weight
|
HOM
|
9f:10m
|
Linear Mixed Model framework, LME, not including Weight
|
0.000145
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Open Field - centre start / Whole arena resting time
|
HOM
|
7f:5m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0728
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Eye Morphology / Fusion between cornea and lens
|
HOM
|
8f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Hematology / Hemoglobin
|
HOM
|
7f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.217
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Combined SHIRPA and Dysmorphology / Coat - color - head
|
HOM
|
8f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Hematology / Mean corpuscular hemoglobin
|
HOM
|
1f:m
|
|
|
NotProcessed |
Serpina1fem1(IMPC)J
|
JAX
|
Hematology / Mean corpuscular hemoglobin
|
HOM
|
5f:5m
|
Linear Mixed Model framework, LME, not including Weight
|
0.00405
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Eye Morphology / Retinal Pigmentation
|
HOM
|
8f:7m
|
|
|
NotProcessed |
Serpina1fem1(IMPC)J
|
JAX
|
Electrocardiogram (ECG) / QTc
|
HOM
|
5f:5m
|
|
|
NotProcessed |
Serpina1fem1(IMPC)J
|
JAX
|
Clinical Chemistry / Aspartate aminotransferase
|
HOM
|
7f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.503
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Combined SHIRPA and Dysmorphology / Hindlimb digit - shape
|
HOM
|
8f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Clinical Chemistry / Total protein
|
HOM
|
7f:8m
|
Linear Mixed Model framework, LME, including Weight
|
3.15×10-05
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Intraperitoneal glucose tolerance test (IPGTT) / Fasted blood glucose concentration
|
HOM
|
8f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.292
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Body Composition (DEXA lean/fat) / Body length
|
HOM
|
8f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.305
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Gross Pathology and Tissue Collection / Heart
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Gross Pathology and Tissue Collection / Heart
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Gross Pathology and Tissue Collection / Heart
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Gross Pathology and Tissue Collection / Heart
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Clinical Chemistry / Total bilirubin
|
HOM
|
5f:5m
|
Linear Mixed Model framework, LME, including Weight
|
0.0942
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Open Field - centre start / Center average speed
|
HOM
|
9f:8m
|
Linear Model Using Generalized Least Squares framework, GLS, including Weight
|
0.000495
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Combined SHIRPA and Dysmorphology / Forelimbs - position
|
HOM
|
8f:7m
|
|
|
NotProcessed |
Serpina1fem1(IMPC)J
|
JAX
|
Electrocardiogram (ECG) / CV
|
HOM
|
8f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.757
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Combined SHIRPA and Dysmorphology / Forepaw - size
|
HOM
|
8f:7m
|
|
|
NotProcessed |
Serpina1fem1(IMPC)J
|
JAX
|
Electrocardiogram (ECG) / pNN5(6>ms)
|
HOM
|
5f:5m
|
|
|
NotProcessed |
Serpina1fem1(IMPC)J
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP3_S
|
HOM
|
8f:7m
|
|
|
NotProcessed |
Serpina1fem1(IMPC)J
|
JAX
|
Body Composition (DEXA lean/fat) / BMC/Body weight
|
HOM
|
8f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.942
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Combined SHIRPA and Dysmorphology / Lower lip morphology
|
HOM
|
8f:7m
|
|
|
NotProcessed |
Serpina1fem1(IMPC)J
|
JAX
|
Combined SHIRPA and Dysmorphology / Skin color - front paws
|
HOM
|
8f:7m
|
|
|
NotProcessed |
Serpina1fem1(IMPC)J
|
JAX
|
Gross Pathology and Tissue Collection / Trachea
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Gross Pathology and Tissue Collection / Trachea
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Gross Pathology and Tissue Collection / Trachea
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Gross Pathology and Tissue Collection / Trachea
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Electrocardiogram (ECG) / QTc Dispersion
|
HOM
|
5f:5m
|
|
|
NotProcessed |
Serpina1fem1(IMPC)J
|
JAX
|
Combined SHIRPA and Dysmorphology / Coat - hair texture / appearance - abdomen
|
HOM
|
8f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Light-Dark Test / Transition
|
HOM
|
9f:10m
|
|
|
NotProcessed |
Serpina1fem1(IMPC)J
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP2_S
|
HOM
|
8f:7m
|
|
|
NotProcessed |
Serpina1fem1(IMPC)J
|
JAX
|
Clinical Chemistry / Glucose
|
HOM
|
5f:5m
|
Linear Mixed Model framework, LME, including Weight
|
0.254
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Light-Dark Test / Time mobile dark side
|
HOM
|
8f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.682
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Eye Morphology / Retinal Blood Vessels Structure
|
HOM
|
8f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Body Weight / General comments about the mouse
|
HOM
|
69f:56m
|
|
|
NotProcessed |
Serpina1fem1(IMPC)J
|
JAX
|
Fertility of Homozygous Knock-out Mice / Gross Findings Female
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Grip Strength / Forelimb and hindlimb grip strength measurement
|
HOM
|
24f:21m
|
|
|
NotProcessed |
Serpina1fem1(IMPC)J
|
JAX
|
Open Field - centre start / Distance travelled - total
|
HOM
|
7f:5m
|
Linear Mixed Model framework, LME, not including Weight
|
0.151
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Combined SHIRPA and Dysmorphology / Forelimb nail - number
|
HOM
|
8f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Urinalysis / microAlbumin (calculated)
|
HOM
|
8f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.990
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Combined SHIRPA and Dysmorphology / Gait
|
HOM
|
8f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Gross Pathology and Tissue Collection / Kidney
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Gross Pathology and Tissue Collection / Kidney
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Gross Pathology and Tissue Collection / Kidney
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Gross Pathology and Tissue Collection / Kidney
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Electrocardiogram (ECG) / QRS
|
HOM
|
8f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.134
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Combined SHIRPA and Dysmorphology / Ears
|
HOM
|
8f:7m
|
|
|
NotProcessed |
Serpina1fem1(IMPC)J
|
JAX
|
Hematology / Platelet count
|
HOM
|
7f:8m
|
Linear Model Using Generalized Least Squares framework, GLS, including Weight
|
0.0155
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Electrocardiogram (ECG) / PQ
|
HOM
|
5f:5m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.285
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Gross Pathology and Tissue Collection / Small intestine
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Gross Pathology and Tissue Collection / Small intestine
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Gross Pathology and Tissue Collection / Small intestine
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Gross Pathology and Tissue Collection / Small intestine
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Light-Dark Test / Percent time in dark
|
HOM
|
9f:10m
|
Linear Mixed Model framework, LME, not including Weight
|
0.586
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Combined SHIRPA and Dysmorphology / Tail - presence
|
HOM
|
8f:7m
|
|
|
NotProcessed |
Serpina1fem1(IMPC)J
|
JAX
|
Open Field - centre start / Whole arena resting time
|
HOM
|
9f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.212
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Clinical Chemistry / Chloride
|
HOM
|
5f:5m
|
Linear Mixed Model framework, LME, including Weight
|
0.822
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Rotarod / Learning difference
|
HOM
|
8f:6m
|
Linear Model Using Generalized Least Squares framework, GLS, including Weight
|
0.0987
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Body Composition (DEXA lean/fat) / Body weight
|
HOM
|
8f:7m
|
|
|
NotProcessed |
Serpina1fem1(IMPC)J
|
JAX
|
Body Composition (DEXA lean/fat) / Lean mass
|
HOM
|
8f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.566
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP3
|
HOM
|
8f:7m
|
|
|
NotProcessed |
Serpina1fem1(IMPC)J
|
JAX
|
Eye Morphology / Pupil Light Response
|
HOM
|
8f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Eye Morphology / Corneal opacity
|
HOM
|
8f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Combined SHIRPA and Dysmorphology / Forelimb digit - number
|
HOM
|
8f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Hematology / White blood cell count
|
HOM
|
1f:m
|
|
|
NotProcessed |
Serpina1fem1(IMPC)J
|
JAX
|
Hematology / White blood cell count
|
HOM
|
5f:5m
|
Linear Mixed Model framework, LME, including Weight
|
0.0910
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Combined SHIRPA and Dysmorphology / Skin color - tail
|
HOM
|
8f:7m
|
|
|
NotProcessed |
Serpina1fem1(IMPC)J
|
JAX
|
Gross Pathology and Tissue Collection / Eye with optic nerve
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Gross Pathology and Tissue Collection / Eye with optic nerve
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Gross Pathology and Tissue Collection / Eye with optic nerve
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Gross Pathology and Tissue Collection / Eye with optic nerve
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Serpina1fem1(IMPC)J
|
JAX
|
Open Field - centre start / Center distance travelled
|
HOM
|
7f:5m
|
Linear Mixed Model framework, LME, including Weight
|
0.173
|
Successful |