Gcshem1(IMPC)H
|
MRC Harwell
|
Combined SHIRPA and Dysmorphology / Forelimb digit - size
|
HET
|
8f:8m
|
|
|
NotProcessed |
Gcshem1(IMPC)H
|
MRC Harwell
|
Combined SHIRPA and Dysmorphology / Tail - thickness
|
HET
|
8f:8m
|
|
|
NotProcessed |
Gcshem1(IMPC)H
|
MRC Harwell
|
Clinical Chemistry / Alanine aminotransferase
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.332
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Combined SHIRPA and Dysmorphology / Coat - hair distribution - back
|
HET
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Eye Morphology / Bulging eye
|
HET
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Combined SHIRPA and Dysmorphology / Forelimb nail - shape
|
HET
|
8f:8m
|
|
|
NotProcessed |
Gcshem1(IMPC)H
|
MRC Harwell
|
Open Field / Whole arena average speed series
|
HET
|
32f:32m
|
|
|
NotProcessed |
Gcshem1(IMPC)H
|
MRC Harwell
|
Electrocardiogram (ECG) / RR
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
9.66×10-05
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Open Field / Center resting time series
|
HET
|
32f:32m
|
|
|
NotProcessed |
Gcshem1(IMPC)H
|
MRC Harwell
|
Combined SHIRPA and Dysmorphology / Skin texture - whole body
|
HET
|
8f:8m
|
|
|
NotProcessed |
Gcshem1(IMPC)H
|
MRC Harwell
|
Combined SHIRPA and Dysmorphology / Trunk curl
|
HET
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Clinical Chemistry / Creatinine
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.227
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Eye Morphology / Iris/Pupil
|
HET
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP2
|
HET
|
8f:8m
|
|
|
NotProcessed |
Gcshem1(IMPC)H
|
MRC Harwell
|
X-ray / Radius
|
HET
|
5f:5m
|
|
|
NotProcessed |
Gcshem1(IMPC)H
|
MRC Harwell
|
X-ray / Fibula
|
HET
|
5f:5m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Open Field / Percentage center time
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.338
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Auditory Brain Stem Response / 6kHz-evoked ABR Threshold
|
HET
|
2f:2m
|
Reference Range Plus Test framework; quantile = 0.95 (Tails probability = 0.025)
|
0.00570
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
X-ray / Shape of vertebrae
|
HET
|
5f:5m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
X-ray / Brachydactyly
|
HET
|
5f:5m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Combined SHIRPA and Dysmorphology / Vibrissae - presence
|
HET
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Gross Pathology and Tissue Collection / Thyroid
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Gross Pathology and Tissue Collection / Thyroid
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Gross Pathology and Tissue Collection / Thyroid
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Gross Pathology and Tissue Collection / Thyroid
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Combined SHIRPA and Dysmorphology / Lower teeth appearance
|
HET
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
X-ray / Scapulae
|
HET
|
5f:5m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Eye Morphology / Lens Opacity
|
HET
|
8f:8m
|
Fisher Exact Test framework
|
0.00288
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Combined SHIRPA and Dysmorphology / Skin texture - back paws
|
HET
|
8f:8m
|
|
|
NotProcessed |
Gcshem1(IMPC)H
|
MRC Harwell
|
Combined SHIRPA and Dysmorphology / Forelimbs - shape
|
HET
|
8f:8m
|
|
|
NotProcessed |
Gcshem1(IMPC)H
|
MRC Harwell
|
Eye Morphology / Retinal Structure
|
HET
|
8f:8m
|
|
|
NotProcessed |
Gcshem1(IMPC)H
|
MRC Harwell
|
Open Field / Periphery distance travelled
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0526
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Eye Morphology / Retina (combined)
|
HET
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
X-ray / Zygomatic bone
|
HET
|
5f:5m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Organ Weight / Body weight
|
HET
|
8f:8m
|
|
|
NotProcessed |
Gcshem1(IMPC)H
|
MRC Harwell
|
Gross Pathology and Tissue Collection / Spleen
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Gross Pathology and Tissue Collection / Spleen
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Gross Pathology and Tissue Collection / Spleen
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Gross Pathology and Tissue Collection / Spleen
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Clinical Chemistry / Calcium
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.450
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Open Field / Percentage center movement time
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.489
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
X-ray / Shape of ribs
|
HET
|
5f:5m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Combined SHIRPA and Dysmorphology / Tail elevation
|
HET
|
8f:8m
|
|
|
NotProcessed |
Gcshem1(IMPC)H
|
MRC Harwell
|
Open Field / Periphery permanence time series
|
HET
|
32f:32m
|
|
|
NotProcessed |
Gcshem1(IMPC)H
|
MRC Harwell
|
Gross Pathology and Tissue Collection / Epididymis
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Gross Pathology and Tissue Collection / Epididymis
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Gross Pathology and Tissue Collection / Epididymis
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Gross Pathology and Tissue Collection / Epididymis
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Combined SHIRPA and Dysmorphology / Contact righting
|
HET
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Combined SHIRPA and Dysmorphology / Skin color - ear
|
HET
|
8f:8m
|
|
|
NotProcessed |
Gcshem1(IMPC)H
|
MRC Harwell
|
Combined SHIRPA and Dysmorphology / Hindlimb nail - number
|
HET
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Grip Strength / Forelimb and hindlimb grip strength normalised against body weight
|
HET
|
8f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0759
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Gross Pathology and Tissue Collection / Esophagus
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Gross Pathology and Tissue Collection / Esophagus
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Gross Pathology and Tissue Collection / Esophagus
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Gross Pathology and Tissue Collection / Esophagus
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Combined SHIRPA and Dysmorphology / Coat - hair texture / appearance - head
|
HET
|
8f:8m
|
|
|
NotProcessed |
Gcshem1(IMPC)H
|
MRC Harwell
|
Grip Strength / Body weight
|
HET
|
8f:7m
|
|
|
NotProcessed |
Gcshem1(IMPC)H
|
MRC Harwell
|
Intraperitoneal glucose tolerance test (IPGTT) / Area under glucose response curve
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0923
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Clinical Chemistry / Creatine kinase
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.812
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Combined SHIRPA and Dysmorphology / Coat - color - abdomen
|
HET
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP1_S
|
HET
|
8f:8m
|
|
|
NotProcessed |
Gcshem1(IMPC)H
|
MRC Harwell
|
Eye Morphology / Pupil Dilation
|
HET
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Clinical Chemistry / Potassium
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.0240
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI3
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.237
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Body Composition (DEXA lean/fat) / Fat mass
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.680
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Auditory Brain Stem Response / 30kHz-evoked ABR Threshold
|
HET
|
2f:2m
|
Reference Range Plus Test framework; quantile = 0.95 (Tails probability = 0.025)
|
0.0125
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Clinical Chemistry / Phosphorus
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.709
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Combined SHIRPA and Dysmorphology / Hindpaw - shape
|
HET
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Combined SHIRPA and Dysmorphology / Tremor
|
HET
|
8f:8m
|
Fisher Exact Test framework
|
0.167
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Combined SHIRPA and Dysmorphology / Genitalia - morphology
|
HET
|
8f:8m
|
|
|
NotProcessed |
Gcshem1(IMPC)H
|
MRC Harwell
|
Viability Primary Screen / Viability Outcome
|
HOM
|
f:m
|
Supplied as data
|
0.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Gross Pathology and Tissue Collection / Lymph node
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Gross Pathology and Tissue Collection / Lymph node
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Gross Pathology and Tissue Collection / Lymph node
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Gross Pathology and Tissue Collection / Lymph node
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Gross Pathology and Tissue Collection / Brain
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Gross Pathology and Tissue Collection / Brain
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Gross Pathology and Tissue Collection / Brain
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Gross Pathology and Tissue Collection / Brain
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Combined SHIRPA and Dysmorphology / Head morphology
|
HET
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Combined SHIRPA and Dysmorphology / Upper teeth appearance
|
HET
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Intraperitoneal glucose tolerance test (IPGTT) / Body Weight
|
HET
|
8f:8m
|
|
|
NotProcessed |
Gcshem1(IMPC)H
|
MRC Harwell
|
Open Field / Center distance travelled
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.493
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Auditory Brain Stem Response / 18kHz-evoked ABR Threshold
|
HET
|
2f:2m
|
Reference Range Plus Test framework; quantile = 0.95 (Tails probability = 0.025)
|
0.0339
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Eye Morphology / Corneal vascularization
|
HET
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Eye Morphology / Retinal Blood Vessels Pattern
|
HET
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Clinical Chemistry / Triglycerides
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.284
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
X-ray / Clavicle
|
HET
|
5f:5m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Body Weight / Body weight curve
|
HET
|
114f:113m
|
|
|
NotProcessed |
Gcshem1(IMPC)H
|
MRC Harwell
|
Open Field / Center permanence time series
|
HET
|
32f:32m
|
|
|
NotProcessed |
Gcshem1(IMPC)H
|
MRC Harwell
|
Combined SHIRPA and Dysmorphology / Activity (body position)
|
HET
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP1
|
HET
|
8f:8m
|
|
|
NotProcessed |
Gcshem1(IMPC)H
|
MRC Harwell
|
Gross Pathology and Tissue Collection / Liver
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Gross Pathology and Tissue Collection / Liver
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Gross Pathology and Tissue Collection / Liver
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Gross Pathology and Tissue Collection / Liver
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Combined SHIRPA and Dysmorphology / Hindlimb digit - size
|
HET
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
X-ray / Digit integrity
|
HET
|
5f:5m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Gross Pathology and Tissue Collection / Thymus
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Gross Pathology and Tissue Collection / Thymus
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Gross Pathology and Tissue Collection / Thymus
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Gross Pathology and Tissue Collection / Thymus
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Eye Morphology / Slit Lamp observation
|
HET
|
f:1m
|
|
|
NotProcessed |
Gcshem1(IMPC)H
|
MRC Harwell
|
Open Field / Periphery distance travelled series
|
HET
|
32f:32m
|
|
|
NotProcessed |
Gcshem1(IMPC)H
|
MRC Harwell
|
Combined SHIRPA and Dysmorphology / Skin texture - snout
|
HET
|
8f:8m
|
|
|
NotProcessed |
Gcshem1(IMPC)H
|
MRC Harwell
|
Clinical Chemistry / Total protein
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.660
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Eye Morphology / Pupil Position
|
HET
|
8f:8m
|
Fisher Exact Test framework
|
0.158
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Combined SHIRPA and Dysmorphology / Hindlimbs - position
|
HET
|
8f:8m
|
|
|
NotProcessed |
Gcshem1(IMPC)H
|
MRC Harwell
|
Body Composition (DEXA lean/fat) / Fat/Body weight
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.149
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Open Field / Latency to center entry
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0584
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Eye Morphology / Eyelid closure
|
HET
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Combined SHIRPA and Dysmorphology / Forelimbs - size
|
HET
|
8f:8m
|
|
|
NotProcessed |
Gcshem1(IMPC)H
|
MRC Harwell
|
X-ray / Fusion of vertebrae
|
HET
|
5f:5m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Gross Pathology and Tissue Collection / Mammary gland
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Gross Pathology and Tissue Collection / Mammary gland
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Gross Pathology and Tissue Collection / Mammary gland
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Gross Pathology and Tissue Collection / Mammary gland
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Combined SHIRPA and Dysmorphology / Tail - morphology
|
HET
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
X-ray / Tibia
|
HET
|
5f:5m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Combined SHIRPA and Dysmorphology / Coat - color pattern - abdomen
|
HET
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Combined SHIRPA and Dysmorphology / Hindlimb nail - length
|
HET
|
8f:8m
|
|
|
NotProcessed |
Gcshem1(IMPC)H
|
MRC Harwell
|
Clinical Chemistry / Aspartate aminotransferase
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.510
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Combined SHIRPA and Dysmorphology / Vocalization
|
HET
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Grip Strength / Forelimb and hindlimb grip strength measurement mean
|
HET
|
8f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.130
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Open Field / Whole arena resting time
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.00484
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
X-ray / Syndactylism
|
HET
|
5f:5m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Combined SHIRPA and Dysmorphology / Teeth presence
|
HET
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Electrocardiogram (ECG) / QTc
|
HET
|
8f:8m
|
|
|
NotProcessed |
Gcshem1(IMPC)H
|
MRC Harwell
|
Eye Morphology / Lens
|
HET
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Grip Strength / Forelimb grip strength normalised against body weight
|
HET
|
8f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.100
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Combined SHIRPA and Dysmorphology / Head size
|
HET
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Eye Morphology / Optic Disc
|
HET
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Combined SHIRPA and Dysmorphology / Coat - color pattern - back
|
HET
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Open Field / Center average speed
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.584
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Eye Morphology / Narrow eye opening
|
HET
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Clinical Chemistry / Sodium
|
HET
|
8f:8m
|
|
|
NotProcessed |
Gcshem1(IMPC)H
|
MRC Harwell
|
Organ Weight / Heart weight
|
HET
|
6f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.763
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Combined SHIRPA and Dysmorphology / Forepaw - shape
|
HET
|
8f:8m
|
|
|
NotProcessed |
Gcshem1(IMPC)H
|
MRC Harwell
|
X-ray / Alive
|
HET
|
5f:5m
|
|
|
NotProcessed |
Gcshem1(IMPC)H
|
MRC Harwell
|
Body Composition (DEXA lean/fat) / Bone Mineral Content (excluding skull)
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.0231
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Combined SHIRPA and Dysmorphology / Skin color - snout
|
HET
|
8f:8m
|
|
|
NotProcessed |
Gcshem1(IMPC)H
|
MRC Harwell
|
Gross Pathology and Tissue Collection / Prostate
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Gross Pathology and Tissue Collection / Prostate
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Gross Pathology and Tissue Collection / Prostate
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Gross Pathology and Tissue Collection / Prostate
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Combined SHIRPA and Dysmorphology / Coat - hair texture / appearance - back
|
HET
|
8f:8m
|
|
|
NotProcessed |
Gcshem1(IMPC)H
|
MRC Harwell
|
Gross Pathology and Tissue Collection / Skin
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Gross Pathology and Tissue Collection / Skin
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Gross Pathology and Tissue Collection / Skin
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Gross Pathology and Tissue Collection / Skin
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Clinical Chemistry / HDL-cholesterol
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.470
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Gross Pathology and Tissue Collection / Lung
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Gross Pathology and Tissue Collection / Lung
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Gross Pathology and Tissue Collection / Lung
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Gross Pathology and Tissue Collection / Lung
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Eye Morphology / Persistence of hyaloid vascular system
|
HET
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI2
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.725
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - S
|
HET
|
8f:8m
|
Linear Model Using Generalized Least Squares framework, GLS, including Weight
|
0.690
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Eye Morphology / Pupil Shape
|
HET
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Intraperitoneal glucose tolerance test (IPGTT) / Blood glucose concentration
|
HET
|
40f:40m
|
|
|
NotProcessed |
Gcshem1(IMPC)H
|
MRC Harwell
|
Open Field / Periphery average speed
|
HET
|
8f:8m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.00176
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Eye Morphology / Eye
|
HET
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
X-ray / Processes on vertebrae
|
HET
|
5f:5m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
X-ray / Maxilla/Pre-maxilla
|
HET
|
5f:5m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Combined SHIRPA and Dysmorphology / Transfer arousal
|
HET
|
8f:8m
|
|
|
NotProcessed |
Gcshem1(IMPC)H
|
MRC Harwell
|
Viability E12.5 Secondary Screen / Outcome
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Gross Pathology and Tissue Collection / Pancreas
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Gross Pathology and Tissue Collection / Pancreas
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Gross Pathology and Tissue Collection / Pancreas
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Gross Pathology and Tissue Collection / Pancreas
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Combined SHIRPA and Dysmorphology / Mouth morphology
|
HET
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
X-ray / Comment on XRay image
|
HET
|
4f:1m
|
|
|
NotProcessed |
Gcshem1(IMPC)H
|
MRC Harwell
|
Combined SHIRPA and Dysmorphology / Head bobbing
|
HET
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Gross Pathology and Tissue Collection / Spinal cord
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Gross Pathology and Tissue Collection / Spinal cord
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Gross Pathology and Tissue Collection / Spinal cord
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Gross Pathology and Tissue Collection / Spinal cord
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Body Composition (DEXA lean/fat) / Lean/Body weight
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.494
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Open Field / Periphery resting time series
|
HET
|
32f:32m
|
|
|
NotProcessed |
Gcshem1(IMPC)H
|
MRC Harwell
|
X-ray / Number of ribs right
|
HET
|
5f:5m
|
|
|
NotProcessed |
Gcshem1(IMPC)H
|
MRC Harwell
|
Combined SHIRPA and Dysmorphology / Skin texture - ear
|
HET
|
8f:8m
|
|
|
NotProcessed |
Gcshem1(IMPC)H
|
MRC Harwell
|
Eye Morphology / Retina
|
HET
|
8f:8m
|
|
|
NotProcessed |
Gcshem1(IMPC)H
|
MRC Harwell
|
Body Composition (DEXA lean/fat) / Body weight
|
HET
|
8f:8m
|
|
|
NotProcessed |
Gcshem1(IMPC)H
|
MRC Harwell
|
Open Field / Distance travelled - total
|
HET
|
8f:8m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.000643
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Combined SHIRPA and Dysmorphology / Snout size
|
HET
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Open Field / Center average speed series
|
HET
|
31f:32m
|
|
|
NotProcessed |
Gcshem1(IMPC)H
|
MRC Harwell
|
Auditory Brain Stem Response / Click-evoked ABR threshold
|
HET
|
2f:2m
|
Reference Range Plus Test framework; quantile = 0.95 (Tails probability = 0.025)
|
0.0568
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Electrocardiogram (ECG) / PR
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.151
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Clinical Chemistry / Alpha-amylase
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.662
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Eye Morphology / Synechia
|
HET
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Clinical Chemistry / Iron
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.0932
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Auditory Brain Stem Response / 24kHz-evoked ABR Threshold
|
HET
|
2f:2m
|
Reference Range Plus Test framework; quantile = 0.95 (Tails probability = 0.025)
|
0.0132
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Clinical Chemistry / Total cholesterol
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.314
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Combined SHIRPA and Dysmorphology / Genitalia - size
|
HET
|
8f:8m
|
|
|
NotProcessed |
Gcshem1(IMPC)H
|
MRC Harwell
|
Open Field / Periphery permanence time
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.269
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Combined SHIRPA and Dysmorphology / Forelimb nail - length
|
HET
|
8f:8m
|
|
|
NotProcessed |
Gcshem1(IMPC)H
|
MRC Harwell
|
Clinical Chemistry / Albumin
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.420
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Electrocardiogram (ECG) / HR
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.000117
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Intraperitoneal glucose tolerance test (IPGTT) / Initial response to glucose challenge
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.972
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Combined SHIRPA and Dysmorphology / Aggression
|
HET
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Open Field / Number of center entries
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.418
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
X-ray / Pelvis
|
HET
|
5f:5m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Grip Strength / Forelimb grip strength measurement mean
|
HET
|
8f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.206
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Combined SHIRPA and Dysmorphology / Startle response
|
HET
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Combined SHIRPA and Dysmorphology / Hindlimbs - shape
|
HET
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Gross Pathology and Tissue Collection / Adrenal gland
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Gross Pathology and Tissue Collection / Adrenal gland
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Gross Pathology and Tissue Collection / Adrenal gland
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Gross Pathology and Tissue Collection / Adrenal gland
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - BN
|
HET
|
8f:8m
|
|
|
NotProcessed |
Gcshem1(IMPC)H
|
MRC Harwell
|
Gross Pathology and Tissue Collection / Urinary bladder
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Gross Pathology and Tissue Collection / Urinary bladder
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Gross Pathology and Tissue Collection / Urinary bladder
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Gross Pathology and Tissue Collection / Urinary bladder
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Viability E9.5 Secondary Screen / Outcome
|
HOM
|
f:m
|
Supplied as data
|
0.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
X-ray / Shape of spine
|
HET
|
5f:5m
|
|
|
NotProcessed |
Gcshem1(IMPC)H
|
MRC Harwell
|
Eye Morphology / Eyelid morphology
|
HET
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Combined SHIRPA and Dysmorphology / Forelimb digit - shape
|
HET
|
8f:8m
|
|
|
NotProcessed |
Gcshem1(IMPC)H
|
MRC Harwell
|
Gross Pathology and Tissue Collection / Gall bladder
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Gross Pathology and Tissue Collection / Gall bladder
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Gross Pathology and Tissue Collection / Gall bladder
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Gross Pathology and Tissue Collection / Gall bladder
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Combined SHIRPA and Dysmorphology / Coat - color - back
|
HET
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
X-ray / Femur
|
HET
|
5f:5m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Eye Morphology / Cornea
|
HET
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Open Field / Center permanence time
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.339
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Auditory Brain Stem Response / 12kHz-evoked ABR Threshold
|
HET
|
2f:2m
|
Reference Range Plus Test framework; quantile = 0.95 (Tails probability = 0.025)
|
0.0621
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Grip Strength / Forelimb grip strength measurement
|
HET
|
24f:21m
|
|
|
NotProcessed |
Gcshem1(IMPC)H
|
MRC Harwell
|
Combined SHIRPA and Dysmorphology / Hindpaw - size
|
HET
|
8f:8m
|
|
|
NotProcessed |
Gcshem1(IMPC)H
|
MRC Harwell
|
Open Field / Whole arena permanence
|
HET
|
8f:8m
|
|
|
NotProcessed |
Gcshem1(IMPC)H
|
MRC Harwell
|
Body Composition (DEXA lean/fat) / Bone Mineral Density (excluding skull)
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.0662
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Combined SHIRPA and Dysmorphology / Upper lip morphology
|
HET
|
8f:8m
|
|
|
NotProcessed |
Gcshem1(IMPC)H
|
MRC Harwell
|
Combined SHIRPA and Dysmorphology / Locomotor activity
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.118
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Clinical Chemistry / LIH (Hemolysis Severity - available on AU analysers)
|
HET
|
8f:8m
|
|
|
NotProcessed |
Gcshem1(IMPC)H
|
MRC Harwell
|
Gross Pathology and Tissue Collection / Skeletal muscle
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Gross Pathology and Tissue Collection / Skeletal muscle
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Gross Pathology and Tissue Collection / Skeletal muscle
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Gross Pathology and Tissue Collection / Skeletal muscle
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Combined SHIRPA and Dysmorphology / Skin texture - tail
|
HET
|
8f:8m
|
|
|
NotProcessed |
Gcshem1(IMPC)H
|
MRC Harwell
|
Eye Morphology / Iris Pigmentation
|
HET
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Combined SHIRPA and Dysmorphology / Vibrissae - appearance
|
HET
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI1
|
HET
|
8f:8m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.0409
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Eye Morphology / Retinal Blood Vessels
|
HET
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
X-ray / Mandibles
|
HET
|
5f:5m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Gross Pathology and Tissue Collection / Seminal vesicle
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Gross Pathology and Tissue Collection / Seminal vesicle
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Gross Pathology and Tissue Collection / Seminal vesicle
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Gross Pathology and Tissue Collection / Seminal vesicle
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
X-ray / Humerus
|
HET
|
5f:5m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Combined SHIRPA and Dysmorphology / Skin color - back paws
|
HET
|
8f:8m
|
|
|
NotProcessed |
Gcshem1(IMPC)H
|
MRC Harwell
|
Gross Pathology and Tissue Collection / Large intestine
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Gross Pathology and Tissue Collection / Large intestine
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Gross Pathology and Tissue Collection / Large intestine
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Gross Pathology and Tissue Collection / Large intestine
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Combined SHIRPA and Dysmorphology / Limb grasp
|
HET
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Combined SHIRPA and Dysmorphology / Skin color - whole body
|
HET
|
8f:8m
|
|
|
NotProcessed |
Gcshem1(IMPC)H
|
MRC Harwell
|
X-ray / Number of digits
|
HET
|
5f:5m
|
|
|
NotProcessed |
Gcshem1(IMPC)H
|
MRC Harwell
|
Combined SHIRPA and Dysmorphology / Coat - hair distribution - abdomen
|
HET
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Open Field / Center distance travelled series
|
HET
|
32f:32m
|
|
|
NotProcessed |
Gcshem1(IMPC)H
|
MRC Harwell
|
Open Field / Whole arena resting time series
|
HET
|
32f:32m
|
|
|
NotProcessed |
Gcshem1(IMPC)H
|
MRC Harwell
|
Clinical Chemistry / Urea (Blood Urea Nitrogen - BUN)
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.974
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Combined SHIRPA and Dysmorphology / Coat - color pattern - head
|
HET
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Combined SHIRPA and Dysmorphology / Genitalia - presence
|
HET
|
8f:8m
|
|
|
NotProcessed |
Gcshem1(IMPC)H
|
MRC Harwell
|
Open Field / Periphery resting time
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.00625
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Combined SHIRPA and Dysmorphology / Hindlimb nail - shape
|
HET
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
X-ray / Ulna
|
HET
|
5f:5m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Combined SHIRPA and Dysmorphology / Coat - hair distribution - head
|
HET
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Gross Pathology and Tissue Collection / Uterus
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Gross Pathology and Tissue Collection / Uterus
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Gross Pathology and Tissue Collection / Uterus
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Gross Pathology and Tissue Collection / Uterus
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Organ Weight / Spleen weight
|
HET
|
6f:6m
|
Linear Mixed Model framework, LME, not including Weight
|
0.100
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Clinical Chemistry / Fructosamine
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.695
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Clinical Chemistry / Alkaline phosphatase
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.0178
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Combined SHIRPA and Dysmorphology / Hindlimb digit - number
|
HET
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Gross Pathology and Tissue Collection / Stomach
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Gross Pathology and Tissue Collection / Stomach
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Gross Pathology and Tissue Collection / Stomach
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Gross Pathology and Tissue Collection / Stomach
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Combined SHIRPA and Dysmorphology / Tail - length
|
HET
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Eye Morphology / Eye Hemorrhage or Blood Presence
|
HET
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Combined SHIRPA and Dysmorphology / Unexpected behaviors
|
HET
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
X-ray / Teeth
|
HET
|
5f:5m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
X-ray / Number of ribs left
|
HET
|
5f:5m
|
|
|
NotProcessed |
Gcshem1(IMPC)H
|
MRC Harwell
|
Open Field / Distance travelled
|
HET
|
32f:32m
|
|
|
NotProcessed |
Gcshem1(IMPC)H
|
MRC Harwell
|
Combined SHIRPA and Dysmorphology / Hindlimbs - size
|
HET
|
8f:8m
|
|
|
NotProcessed |
Gcshem1(IMPC)H
|
MRC Harwell
|
Combined SHIRPA and Dysmorphology / Skin texture - front paws
|
HET
|
8f:8m
|
|
|
NotProcessed |
Gcshem1(IMPC)H
|
MRC Harwell
|
Body Composition (DEXA lean/fat) / Bone Area
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.520
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Body Weight / Body weight
|
HET
|
88f:88m
|
|
|
NotProcessed |
Gcshem1(IMPC)H
|
MRC Harwell
|
Eye Morphology / Fusion between cornea and lens
|
HET
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Combined SHIRPA and Dysmorphology / Coat - color - head
|
HET
|
8f:8m
|
|
|
NotProcessed |
Gcshem1(IMPC)H
|
MRC Harwell
|
Electrocardiogram (ECG) / QT
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
3.15×10-05
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Eye Morphology / Retinal Pigmentation
|
HET
|
8f:8m
|
|
|
NotProcessed |
Gcshem1(IMPC)H
|
MRC Harwell
|
Combined SHIRPA and Dysmorphology / Hindlimb digit - shape
|
HET
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Combined SHIRPA and Dysmorphology / Forepaw - size
|
HET
|
8f:8m
|
|
|
NotProcessed |
Gcshem1(IMPC)H
|
MRC Harwell
|
Intraperitoneal glucose tolerance test (IPGTT) / Fasted blood glucose concentration
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.512
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Gross Pathology and Tissue Collection / Heart
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Gross Pathology and Tissue Collection / Heart
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Gross Pathology and Tissue Collection / Heart
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Gross Pathology and Tissue Collection / Heart
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Clinical Chemistry / Total bilirubin
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.294
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Combined SHIRPA and Dysmorphology / Forelimbs - position
|
HET
|
8f:8m
|
|
|
NotProcessed |
Gcshem1(IMPC)H
|
MRC Harwell
|
X-ray / Fusion of ribs
|
HET
|
5f:5m
|
|
|
NotProcessed |
Gcshem1(IMPC)H
|
MRC Harwell
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP3_S
|
HET
|
8f:8m
|
|
|
NotProcessed |
Gcshem1(IMPC)H
|
MRC Harwell
|
Body Composition (DEXA lean/fat) / BMC/Body weight
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.154
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Combined SHIRPA and Dysmorphology / Lower lip morphology
|
HET
|
8f:8m
|
|
|
NotProcessed |
Gcshem1(IMPC)H
|
MRC Harwell
|
Combined SHIRPA and Dysmorphology / Skin color - front paws
|
HET
|
8f:8m
|
|
|
NotProcessed |
Gcshem1(IMPC)H
|
MRC Harwell
|
Gross Pathology and Tissue Collection / Trachea
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Gross Pathology and Tissue Collection / Trachea
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Gross Pathology and Tissue Collection / Trachea
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Gross Pathology and Tissue Collection / Trachea
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Gross Pathology and Tissue Collection / Testes
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Gross Pathology and Tissue Collection / Testes
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Gross Pathology and Tissue Collection / Testes
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Gross Pathology and Tissue Collection / Testes
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Combined SHIRPA and Dysmorphology / Coat - hair texture / appearance - abdomen
|
HET
|
8f:8m
|
|
|
NotProcessed |
Gcshem1(IMPC)H
|
MRC Harwell
|
Open Field / Center resting time
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.307
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP2_S
|
HET
|
8f:8m
|
|
|
NotProcessed |
Gcshem1(IMPC)H
|
MRC Harwell
|
Clinical Chemistry / Glucose
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.809
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Eye Morphology / Retinal Blood Vessels Structure
|
HET
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
X-ray / Joints
|
HET
|
5f:5m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Grip Strength / Forelimb and hindlimb grip strength measurement
|
HET
|
24f:21m
|
|
|
NotProcessed |
Gcshem1(IMPC)H
|
MRC Harwell
|
X-ray / Skull shape
|
HET
|
5f:5m
|
Fisher Exact Test framework
|
0.0817
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Combined SHIRPA and Dysmorphology / Forelimb nail - number
|
HET
|
8f:8m
|
|
|
NotProcessed |
Gcshem1(IMPC)H
|
MRC Harwell
|
Combined SHIRPA and Dysmorphology / Gait
|
HET
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Gross Pathology and Tissue Collection / Kidney
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Gross Pathology and Tissue Collection / Kidney
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Gross Pathology and Tissue Collection / Kidney
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Gross Pathology and Tissue Collection / Kidney
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Electrocardiogram (ECG) / QRS
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.471
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Combined SHIRPA and Dysmorphology / Ears
|
HET
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Open Field / Periphery average speed series
|
HET
|
32f:32m
|
|
|
NotProcessed |
Gcshem1(IMPC)H
|
MRC Harwell
|
Gross Pathology and Tissue Collection / Small intestine
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Gross Pathology and Tissue Collection / Small intestine
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Gross Pathology and Tissue Collection / Small intestine
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Gross Pathology and Tissue Collection / Small intestine
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Combined SHIRPA and Dysmorphology / Forelimb digit - number
|
HET
|
8f:8m
|
|
|
NotProcessed |
Gcshem1(IMPC)H
|
MRC Harwell
|
Combined SHIRPA and Dysmorphology / Tail - presence
|
HET
|
8f:8m
|
|
|
NotProcessed |
Gcshem1(IMPC)H
|
MRC Harwell
|
Clinical Chemistry / Chloride
|
HET
|
8f:8m
|
|
|
NotProcessed |
Gcshem1(IMPC)H
|
MRC Harwell
|
X-ray / Tibia length
|
HET
|
5f:5m
|
Linear Mixed Model framework, LME, including Weight
|
0.000221
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Body Composition (DEXA lean/fat) / Lean mass
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.918
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP3
|
HET
|
8f:8m
|
|
|
NotProcessed |
Gcshem1(IMPC)H
|
MRC Harwell
|
Eye Morphology / Pupil Light Response
|
HET
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Open Field / Whole arena average speed
|
HET
|
8f:8m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.000643
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Eye Morphology / Corneal opacity
|
HET
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Gross Pathology and Tissue Collection / Ovary
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Gross Pathology and Tissue Collection / Ovary
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Gross Pathology and Tissue Collection / Ovary
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Gross Pathology and Tissue Collection / Ovary
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Combined SHIRPA and Dysmorphology / Skin color - tail
|
HET
|
8f:8m
|
|
|
NotProcessed |
Gcshem1(IMPC)H
|
MRC Harwell
|
Gross Pathology and Tissue Collection / Eye with optic nerve
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Gross Pathology and Tissue Collection / Eye with optic nerve
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Gross Pathology and Tissue Collection / Eye with optic nerve
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Gcshem1(IMPC)H
|
MRC Harwell
|
Gross Pathology and Tissue Collection / Eye with optic nerve
|
HET
|
f:m
|
Supplied as data
|
1.00
|
Successful |