Mkrn2em1(IMPC)Wtsi
|
WTSI
|
Clinical Chemistry / Free fatty acids
|
HOM
|
5f:6m
|
Linear Mixed Model framework, LME, including Weight
|
0.173
|
Successful |
Mkrn2tm1b(KOMP)Wtsi
|
WTSI
|
Clinical Chemistry / Free fatty acids
|
HOM
|
6f:6m
|
Linear Mixed Model framework, LME, including Weight
|
0.874
|
Successful |
Mkrn2tm1b(KOMP)Wtsi
|
WTSI
|
Clinical Chemistry / Alanine aminotransferase
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.124
|
Successful |
Mkrn2em1(IMPC)Wtsi
|
WTSI
|
Clinical Chemistry / Alanine aminotransferase
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.829
|
Successful |
Mkrn2em1(IMPC)Wtsi
|
WTSI
|
Indirect Calorimetry / Heat production (metabolic rate)
|
HOM
|
f:132m
|
|
|
NotProcessed |
Mkrn2tm1b(KOMP)Wtsi
|
WTSI
|
Indirect Calorimetry / Heat production (metabolic rate)
|
HOM
|
f:154m
|
|
|
NotProcessed |
Mkrn2em1(IMPC)Wtsi
|
WTSI
|
Clinical Chemistry / Calcium
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.0250
|
Successful |
Mkrn2tm1b(KOMP)Wtsi
|
WTSI
|
Clinical Chemistry / Calcium
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.161
|
Successful |
Mkrn2em1(IMPC)Wtsi
|
WTSI
|
Clinical Chemistry / Creatinine
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.171
|
Successful |
Mkrn2tm1b(KOMP)Wtsi
|
WTSI
|
Clinical Chemistry / Creatinine
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.498
|
Successful |
Mkrn2tm1b(KOMP)Wtsi
|
WTSI
|
Clinical Chemistry / Glucose
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.00269
|
Successful |
Mkrn2em1(IMPC)Wtsi
|
WTSI
|
Clinical Chemistry / Glucose
|
HOM
|
6f:6m
|
Linear Mixed Model framework, LME, including Weight
|
0.0471
|
Successful |
Mkrn2tm1b(KOMP)Wtsi
|
WTSI
|
Clinical Chemistry / Fructosamine
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.483
|
Successful |
Mkrn2em1(IMPC)Wtsi
|
WTSI
|
Clinical Chemistry / Fructosamine
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.558
|
Successful |
Mkrn2em1(IMPC)Wtsi
|
WTSI
|
Clinical Chemistry / Sodium
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.307
|
Successful |
Mkrn2tm1b(KOMP)Wtsi
|
WTSI
|
Clinical Chemistry / Sodium
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.499
|
Successful |
Mkrn2em1(IMPC)Wtsi
|
WTSI
|
Clinical Chemistry / Alkaline phosphatase
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.000313
|
Successful |
Mkrn2tm1b(KOMP)Wtsi
|
WTSI
|
Clinical Chemistry / Alkaline phosphatase
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.000373
|
Successful |
Mkrn2tm1b(KOMP)Wtsi
|
WTSI
|
Clinical Chemistry / Glycerol
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.102
|
Successful |
Mkrn2em1(IMPC)Wtsi
|
WTSI
|
Clinical Chemistry / Glycerol
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.803
|
Successful |
Mkrn2tm1b(KOMP)Wtsi
|
WTSI
|
Clinical Chemistry / Alpha-amylase
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.0117
|
Successful |
Mkrn2em1(IMPC)Wtsi
|
WTSI
|
Clinical Chemistry / Alpha-amylase
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.140
|
Successful |
Mkrn2tm1b(KOMP)Wtsi
|
WTSI
|
Clinical Chemistry / Iron
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.0645
|
Successful |
Mkrn2em1(IMPC)Wtsi
|
WTSI
|
Clinical Chemistry / Iron
|
HOM
|
6f:6m
|
Linear Mixed Model framework, LME, including Weight
|
0.347
|
Successful |
Mkrn2tm1b(KOMP)Wtsi
|
WTSI
|
Clinical Chemistry / Magnesium
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.0485
|
Successful |
Mkrn2em1(IMPC)Wtsi
|
WTSI
|
Clinical Chemistry / Magnesium
|
HOM
|
6f:6m
|
Linear Mixed Model framework, LME, including Weight
|
0.962
|
Successful |
Mkrn2tm1b(KOMP)Wtsi
|
WTSI
|
Clinical Chemistry / Creatine kinase
|
HOM
|
6f:6m
|
Linear Mixed Model framework, LME, including Weight
|
0.0230
|
Successful |
Mkrn2em1(IMPC)Wtsi
|
WTSI
|
Clinical Chemistry / Creatine kinase
|
HOM
|
5f:6m
|
Linear Mixed Model framework, LME, including Weight
|
0.491
|
Successful |
Mkrn2tm1b(KOMP)Wtsi
|
WTSI
|
Intraperitoneal glucose tolerance test (IPGTT) / Area under glucose response curve
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.908
|
Successful |
Mkrn2em1(IMPC)Wtsi
|
WTSI
|
Intraperitoneal glucose tolerance test (IPGTT) / Area under glucose response curve
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.928
|
Successful |
Mkrn2em1(IMPC)Wtsi
|
WTSI
|
Clinical Chemistry / Total cholesterol
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.00442
|
Successful |
Mkrn2tm1b(KOMP)Wtsi
|
WTSI
|
Clinical Chemistry / Total cholesterol
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.259
|
Successful |
Mkrn2tm1b(KOMP)Wtsi
|
WTSI
|
Clinical Chemistry / Total protein
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.174
|
Successful |
Mkrn2em1(IMPC)Wtsi
|
WTSI
|
Clinical Chemistry / Total protein
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.561
|
Successful |
Mkrn2em1(IMPC)Wtsi
|
WTSI
|
Body Composition (DEXA lean/fat) / Fat/Body weight
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.519
|
Successful |
Mkrn2tm1b(KOMP)Wtsi
|
WTSI
|
Body Composition (DEXA lean/fat) / Fat/Body weight
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.559
|
Successful |
Mkrn2tm1b(KOMP)Wtsi
|
WTSI
|
Indirect Calorimetry / Oxygen consumption
|
HOM
|
f:154m
|
|
|
NotProcessed |
Mkrn2em1(IMPC)Wtsi
|
WTSI
|
Indirect Calorimetry / Oxygen consumption
|
HOM
|
f:132m
|
|
|
NotProcessed |
Mkrn2tm1b(KOMP)Wtsi
|
WTSI
|
Clinical Chemistry / Albumin
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.0652
|
Successful |
Mkrn2em1(IMPC)Wtsi
|
WTSI
|
Clinical Chemistry / Albumin
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.635
|
Successful |
Mkrn2em1(IMPC)Wtsi
|
WTSI
|
Body Composition (DEXA lean/fat) / Fat mass
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.00144
|
Successful |
Mkrn2tm1b(KOMP)Wtsi
|
WTSI
|
Body Composition (DEXA lean/fat) / Fat mass
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.00204
|
Successful |
Mkrn2tm1b(KOMP)Wtsi
|
WTSI
|
Clinical Chemistry / Potassium
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.00415
|
Successful |
Mkrn2em1(IMPC)Wtsi
|
WTSI
|
Clinical Chemistry / Potassium
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.819
|
Successful |
Mkrn2tm1b(KOMP)Wtsi
|
WTSI
|
Intraperitoneal glucose tolerance test (IPGTT) / Initial response to glucose challenge
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.118
|
Successful |
Mkrn2em1(IMPC)Wtsi
|
WTSI
|
Intraperitoneal glucose tolerance test (IPGTT) / Initial response to glucose challenge
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.422
|
Successful |
Mkrn2tm1b(KOMP)Wtsi
|
WTSI
|
Clinical Chemistry / Phosphorus
|
HOM
|
7f:6m
|
Linear Mixed Model framework, LME, including Weight
|
0.0618
|
Successful |
Mkrn2em1(IMPC)Wtsi
|
WTSI
|
Clinical Chemistry / Phosphorus
|
HOM
|
5f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.656
|
Successful |
Mkrn2em1(IMPC)Wtsi
|
WTSI
|
Clinical Chemistry / HDL-cholesterol
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.000580
|
Successful |
Mkrn2tm1b(KOMP)Wtsi
|
WTSI
|
Clinical Chemistry / HDL-cholesterol
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.968
|
Successful |
Mkrn2em1(IMPC)Wtsi
|
WTSI
|
Clinical Chemistry / Thyroxine
|
HOM
|
7f:6m
|
Linear Mixed Model framework, LME, including Weight
|
0.275
|
Successful |
Mkrn2tm1b(KOMP)Wtsi
|
WTSI
|
Clinical Chemistry / Thyroxine
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.566
|
Successful |
Mkrn2tm1b(KOMP)Wtsi
|
WTSI
|
Clinical Chemistry / Chloride
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.104
|
Successful |
Mkrn2em1(IMPC)Wtsi
|
WTSI
|
Clinical Chemistry / Chloride
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.802
|
Successful |
Mkrn2em1(IMPC)Wtsi
|
WTSI
|
Insulin Blood Level / Insulin
|
HOM
|
5f:6m
|
Linear Mixed Model framework, LME, including Weight
|
0.289
|
Successful |
Mkrn2tm1b(KOMP)Wtsi
|
WTSI
|
Insulin Blood Level / Insulin
|
HOM
|
3f:5m
|
Linear Mixed Model framework, LME, including Weight
|
0.700
|
Successful |
Mkrn2em1(IMPC)Wtsi
|
WTSI
|
Intraperitoneal glucose tolerance test (IPGTT) / Blood glucose concentration
|
HOM
|
35f:35m
|
|
|
NotProcessed |
Mkrn2tm1b(KOMP)Wtsi
|
WTSI
|
Intraperitoneal glucose tolerance test (IPGTT) / Blood glucose concentration
|
HOM
|
35f:35m
|
|
|
NotProcessed |
Mkrn2tm1b(KOMP)Wtsi
|
WTSI
|
Intraperitoneal glucose tolerance test (IPGTT) / Fasted blood glucose concentration
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0397
|
Successful |
Mkrn2em1(IMPC)Wtsi
|
WTSI
|
Intraperitoneal glucose tolerance test (IPGTT) / Fasted blood glucose concentration
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.324
|
Successful |
Mkrn2em1(IMPC)Wtsi
|
WTSI
|
Clinical Chemistry / Total bilirubin
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.0721
|
Successful |
Mkrn2tm1b(KOMP)Wtsi
|
WTSI
|
Clinical Chemistry / Total bilirubin
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.0895
|
Successful |
Mkrn2tm1b(KOMP)Wtsi
|
WTSI
|
Clinical Chemistry / Aspartate aminotransferase
|
HOM
|
7f:6m
|
Linear Mixed Model framework, LME, including Weight
|
5.11×10-08
|
Successful |
Mkrn2em1(IMPC)Wtsi
|
WTSI
|
Clinical Chemistry / Aspartate aminotransferase
|
HOM
|
5f:6m
|
Linear Mixed Model framework, LME, including Weight
|
0.567
|
Successful |
Mkrn2tm1b(KOMP)Wtsi
|
WTSI
|
Indirect Calorimetry / Respiratory Exchange Ratio
|
HOM
|
f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.0491
|
Successful |
Mkrn2em1(IMPC)Wtsi
|
WTSI
|
Indirect Calorimetry / Respiratory Exchange Ratio
|
HOM
|
f:6m
|
Linear Mixed Model framework, LME, including Weight
|
0.650
|
Successful |
Mkrn2tm1b(KOMP)Wtsi
|
WTSI
|
Clinical Chemistry / LDL-cholesterol
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.427
|
Successful |
Mkrn2em1(IMPC)Wtsi
|
WTSI
|
Clinical Chemistry / LDL-cholesterol
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.602
|
Successful |
Mkrn2em1(IMPC)Wtsi
|
WTSI
|
Indirect Calorimetry / Carbon dioxide production
|
HOM
|
f:132m
|
|
|
NotProcessed |
Mkrn2tm1b(KOMP)Wtsi
|
WTSI
|
Indirect Calorimetry / Carbon dioxide production
|
HOM
|
f:154m
|
|
|
NotProcessed |
Mkrn2em1(IMPC)Wtsi
|
WTSI
|
Clinical Chemistry / Triglycerides
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.0518
|
Successful |
Mkrn2tm1b(KOMP)Wtsi
|
WTSI
|
Clinical Chemistry / Triglycerides
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.168
|
Successful |
Mkrn2em1(IMPC)Wtsi
|
WTSI
|
Clinical Chemistry / Urea (Blood Urea Nitrogen - BUN)
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.126
|
Successful |
Mkrn2tm1b(KOMP)Wtsi
|
WTSI
|
Clinical Chemistry / Urea (Blood Urea Nitrogen - BUN)
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.187
|
Successful |