All data for Duoxa2

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Allele Center Procedure / Parameter Zygosity Mutants Statistical
Method
P Value Status Graph
Duoxa2tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Total T cells - % of CD45+ HOM 6f:6m Manual 0.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Forepaw footpad size HOM 7f:7m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Duoxa2tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Effector gd cells - % of CD45+ HOM 6f:6m Manual 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Eye Morphology / Bulging eye HOM 7f:7m Fisher Exact Test framework 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / External genitalia morphology HOM 7f:7m Fisher Exact Test framework 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Total CD4+ NKT cells - % of CD45+ HOM 6f:6m Manual 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / B cell number HOM 7f:7m 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / NKT cell number HOM 7f:7m 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Bone marrow immunophenotyping / Pre-pro B cells (Hardy fraction A) - % of B220+ HOM 5f:5m Manual 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / KLRG1+ Treg cells - % of CD45+ HOM 6f:6m Manual 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Eye Morphology / Iris/Pupil HOM 7f:7m Fisher Exact Test framework 3.8398E-05 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Snout morphology HOM 7f:7m Fisher Exact Test framework 2.3110E-19 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Hematology / Mean cell hemoglobin concentration HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 2.8049E-05 Success
Duoxa2tm1b(KOMP)Wtsi WTSI X-ray / Kyphosis HOM 7f:7m Fisher Exact Test framework 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI X-ray / Lumbar processes HOM 7f:7m Fisher Exact Test framework 4.2797E-37 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Incisors morphology HOM 7f:7m Fisher Exact Test framework 0.041552 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Total B cells - % of CD45+ HOM 2f:2m Manual 1.0000 Not processed - Data analysis pending
Duoxa2tm1b(KOMP)Wtsi WTSI Indirect Calorimetry / Total food intake HOM 0f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 2.5924E-08 Success
Duoxa2tm1b(KOMP)Wtsi WTSI X-ray / Fibula HOM 7f:7m Fisher Exact Test framework 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI X-ray / Shape of vertebrae HOM 7f:7m Fisher Exact Test framework 1.8484E-19 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Auditory Brain Stem Response / 6kHz-evoked ABR Threshold HOM 2f:6m 6.6812E-12 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Trunk curl HOM 7f:7m Fisher Exact Test framework 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Naive CD8+ T cells - % of CD8+ HOM 6f:6m Manual 0.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Effector gd T cells - % of gd T cells HOM 6f:6m Manual 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Body Composition (DEXA lean/fat) / Body length HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 5.1315E-199 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / KLRG1+ gd T cells - % of CD45+ HOM 6f:6m Manual 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Plasmacytoid DC - % of DC HOM 3f:3m Manual 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Eye Morphology / Lens Opacity HOM 7f:7m Fisher Exact Test framework 0.036581 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Limb skin appearance HOM 7f:7m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Duoxa2tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Ly6C+ mature NK cells - % of mature NK cells HOM 5f:5m Manual 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Conventional DC (cDC) - % of CD45+ HOM 5f:5m Manual 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / Ly6Clow monocyte percentage HOM 7f:7m 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Follicular B cells - % of B2 cells HOM 6f:6m Manual 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Hindlimb size HOM 7f:7m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Duoxa2tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Forepaw morphology HOM 7f:7m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Duoxa2tm1b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Effector CD4+ T helper cells - % of CD45+ HOM 6f:6m Manual 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / KLRG1+ Treg cells - % of Treg HOM 6f:6m Manual 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Follicular B cells - % of CD45+ HOM 2f:2m Manual 1.0000 Not processed - Data analysis pending
Duoxa2tm1b(KOMP)Wtsi WTSI X-ray / Zygomatic bone HOM 7f:7m Fisher Exact Test framework 8.7306E-35 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Head skin colour HOM 7f:7m Fisher Exact Test framework 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Head coat/hair length HOM 7f:7m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Duoxa2tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Ventral coat/hair colour pattern HOM 7f:7m Fisher Exact Test framework 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Limb coat/hair length HOM 7f:7m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Duoxa2tm1b(KOMP)Wtsi WTSI X-ray / Shape of ribs HOM 7f:7m Fisher Exact Test framework 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / CD4+ T helper cells - % of CD4+ HOM 6f:6m Manual 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Grip Strength / Forelimb and hindlimb grip strength normalised against body weight HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 2.4959E-11 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Macrophages - % of CD45+ HOM 3f:3m Manual 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / CD4+ T helper cells - % of CD45+ HOM 6f:6m Manual 0.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / CD4+ alpha beta T cell percentage HOM 7f:7m 3.0875E-15 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Tail length HOM 7f:7m Fisher Exact Test framework 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / KLRG1+ CD4+ NKT cells - % of CD45+ HOM 6f:6m Manual 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Total CD4- NKT cells - % of NKT cells HOM 6f:6m Manual 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Bone marrow immunophenotyping / Myeloid cells - % of CD45+ HOM 5f:5m Manual 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Auditory Brain Stem Response / 30kHz-evoked ABR Threshold HOM 2f:6m 1.0683E-12 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / KLRG1+ CD4+ T helper cells - % of CD4+ T helper cells HOM 6f:6m Manual 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Total CD8+ T cells - % of CD45+ HOM 6f:6m Manual 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Germinal centre B cells - % of B2 cells HOM 2f:2m Manual 1.0000 Not processed - Data analysis pending
Duoxa2tm1b(KOMP)Wtsi WTSI Viability Primary Screen / Outcome HOM 199f:229m Supplied as data Success
Duoxa2tm1b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / KLRG1+ CD4- NKT cells - % of CD4- NKT cells HOM 6f:6m Manual 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Plasmacytoid DC - % of DC HOM 5f:5m Manual 0.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Head bobbing/circling HOM 7f:7m Fisher Exact Test framework 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Forepaw nail colour HOM 7f:7m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Duoxa2tm1b(KOMP)Wtsi WTSI Indirect Calorimetry / Respiratory Exchange Ratio HOM 0f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.0024684 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Digit coat/hair colour pattern HOM 7f:7m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Duoxa2tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / B1a cells - % of CD45+ HOM 6f:6m Manual 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Resting CD8+ T cells - % of CD45+ HOM 6f:6m Manual 0.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Eye Morphology / Corneal vascularization HOM 7f:7m Fisher Exact Test framework 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Eye Morphology / Retinal Blood Vessels Pattern HOM 7f:7m Fisher Exact Test framework 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Head size HOM 7f:7m Fisher Exact Test framework 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Hematology / Platelet count HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 8.3388E-05 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / CD4+ CD44+ CD62L- alpha beta effector T cell percentage HOM 7f:7m 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / External genitalia HOM 7f:7m Fisher Exact Test framework 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Resting gd T cells - % of CD45+ HOM 6f:6m Manual 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Resting CD4+ T helper cells - % of CD45+ HOM 6f:6m Manual 0.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Hindlimb morphology HOM 7f:7m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Duoxa2tm1b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Follicular B cells - % of B2 cells HOM 2f:2m Manual 1.0000 Not processed - Data analysis pending
Duoxa2tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / KLRG1+ CD4- NKT cells - % of CD45+ HOM 6f:6m Manual 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / CD8+ KLRG1+ alpha beta T cell number HOM 7f:7m 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Transfer arousal HOM 7f:7m Fisher Exact Test framework 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / Gamma delta T cell number HOM 7f:7m 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Eye Morphology / Pupil Position HOM 7f:7m Fisher Exact Test framework 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Limb skin colour HOM 7f:7m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Duoxa2tm1b(KOMP)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / CD8+ CD44+ CD62L- alpha beta effector T cell percentage HOM 7f:7m 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Ear epidermis immunophenotyping / Average volume of LC HOM 2f:2m Manual 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / KLRG1+ CD8+ T cells - % of CD8+ HOM 6f:6m Manual 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI X-ray / Scoliosis HOM 7f:7m Fisher Exact Test framework 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Incisor colour HOM 7f:7m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Duoxa2tm1b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Plasmacytoid DC - % of CD45+ HOM 5f:5m Manual 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / Neutrophil percentage HOM 7f:7m 2.4159E-05 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Early germinal centre B cells - % of CD45+ HOM 6f:6m Manual 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI X-ray / Fusion of vertebrae HOM 7f:7m Fisher Exact Test framework 0.61841 Success
Duoxa2tm1b(KOMP)Wtsi WTSI X-ray / Tibia HOM 7f:7m Fisher Exact Test framework 1.9308E-35 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Conventional DC (cDC) - % of CD45+ HOM 3f:3m Manual 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / CD5+ gd T cells - % of gd T cells HOM 6f:6m Manual 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Head skin appearance HOM 7f:7m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Duoxa2tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Resting Treg cells - % of CD45+ HOM 6f:6m Manual 0.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Grip Strength / Forelimb and hindlimb grip strength measurement mean HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 8.9857E-15 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Paw footpad skin appearance HOM 7f:7m Fisher Exact Test framework 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Resting CD4+ NKT cells - % of CD45+ HOM 6f:6m Manual 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / CD8+ alpha beta T cell percentage HOM 7f:7m 2.7452E-05 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Total CD4+ T cells - % of ab T cells HOM 6f:6m Manual 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Digit coat/hair appearance HOM 7f:7m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Duoxa2tm1b(KOMP)Wtsi WTSI Eye Morphology / Lens HOM 7f:7m Fisher Exact Test framework 0.036581 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Resting gd T cells - % of gd T cells HOM 6f:6m Manual 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Grip Strength / Forelimb grip strength normalised against body weight HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 1.0114E-13 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Effector CD4+ T helper cells - % of CD45+ HOM 6f:6m Manual 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / CD11b-high cDC - % of CD45+ HOM 3f:3m Manual 0.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Tail morphology HOM 7f:7m Fisher Exact Test framework 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / KLRG1+ mature NK cell percentage HOM 7f:7m 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Resting CD4+ T helper cells - % of CD4+ T helper cells HOM 6f:6m Manual 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Total B cells - % of CD45+ HOM 6f:6m Manual 0.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Ventral coat/hair colour HOM 7f:7m Fisher Exact Test framework 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Germinal centre B cells - % of CD45+ HOM 6f:6m Manual 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Body Composition (DEXA lean/fat) / Bone Mineral Content (excluding skull) HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 3.2701E-15 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Ly6C+ NKT cells - % of NKT cells HOM 5f:5m Manual 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Corneal touch reflex HOM 7f:7m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Duoxa2tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / CD11b-low cDC - % of CD45+ HOM 3f:3m Manual 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Contact righting reflex HOM 7f:7m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Duoxa2tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Forepaw nail morphology HOM 7f:7m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Duoxa2tm1b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Effector CD8+ T cells - % of CD45+ HOM 6f:6m Manual 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Eye Morphology / Persistence of hyaloid vascular system HOM 7f:7m Fisher Exact Test framework 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Effector NK cells - % of CD45+ HOM 6f:6m Manual 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Bone marrow immunophenotyping / Granulocytes - % of CD45+ HOM 5f:5m Manual 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI X-ray / Maxilla/Pre-maxilla HOM 7f:7m Fisher Exact Test framework 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Mature NK cells - % of NK cellls HOM 5f:5m Manual 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Gait (inc. ataxia) HOM 7f:7m Fisher Exact Test framework 0.0011808 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Effector CD4- NKT cells - % of CD45+ HOM 6f:6m Manual 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Tail coat/hair appearance HOM 7f:7m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Duoxa2tm1b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Naive CD8+ T cells - % of CD45+ HOM 6f:6m Manual 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Resting NK cells - % of NK cells HOM 6f:6m Manual 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI X-ray / Caudal processes HOM 7f:7m Fisher Exact Test framework 8.2712E-35 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Ventral skin appearance HOM 7f:7m Fisher Exact Test framework 0.0035256 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Hindlimb HOM 7f:7m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Duoxa2tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Total B2 cells - % of CD45+ HOM 6f:6m Manual 0.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Head morphology HOM 7f:7m Fisher Exact Test framework 6.8989E-05 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Dorsal coat/hair colour HOM 7f:7m Fisher Exact Test framework 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI X-ray / Number of ribs right HOM 7f:7m 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Resting CD4+ NKT cells - % of CD45+ HOM 6f:6m Manual 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Total DC - % of CD45+ HOM 5f:5m Manual 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / CD4+ CD25+ alpha beta regulatory T cell percentage HOM 7f:7m 0.0077498 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / KLRG1+ gd T cells - % of CD45+ HOM 6f:6m Manual 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / KLRG1+ CD4+ T helper cells - % of CD45+ HOM 6f:6m Manual 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Resting CD4- NKT cells - % of CD4- NKT cells HOM 6f:6m Manual 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Resting Treg cells - % of Treg HOM 6f:6m Manual 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Transitional 1 B cells - % of B2 cells HOM 6f:6m Manual 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Convulsions HOM 7f:7m Fisher Exact Test framework 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Plasmacytoid DC - % of CD45+ HOM 3f:3m Manual 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Forepaw digit size HOM 7f:7m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Duoxa2tm1b(KOMP)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / Monocyte number HOM 7f:7m 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Effector CD4+ T helper cells - % of CD4+ T helper cells HOM 6f:6m Manual 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Hindpaw digit fusion HOM 7f:7m Fisher Exact Test framework 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / CD103+ CD11b-low cDC - % of CD45+ HOM 3f:3m Manual 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Effector Treg cells - % of CD45+ HOM 6f:6m Manual 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Ear epidermis immunophenotyping / Average branch length of LC HOM 2f:2m Manual 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Effector NK cells - % of NK cells HOM 6f:6m Manual 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Tail HOM 7f:7m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Duoxa2tm1b(KOMP)Wtsi WTSI Grip Strength / Forelimb grip strength measurement mean HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 1.7167E-14 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Resting Treg cells - % of Treg HOM 6f:6m Manual 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Ventral coat/hair appearance HOM 7f:7m Fisher Exact Test framework 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI DSS Histology / Pre-Day 10 Death HOM 2f:2m - 1.0000 FAILED - Not enough mutant or control data
Duoxa2tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Limb coat/hair appearance HOM 7f:7m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Duoxa2tm1b(KOMP)Wtsi WTSI X-ray / Femur HOM 7f:7m Fisher Exact Test framework 2.3203E-32 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / Eosinophil number HOM 7f:7m 0.30923 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Pinna HOM 7f:7m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Duoxa2tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Resting CD4+ T helper cells - % of CD45+ HOM 6f:6m Manual 0.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Eye Morphology / Cornea HOM 7f:7m Fisher Exact Test framework 0.10496 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Germinal centre B cells - % of B2 cells HOM 6f:6m Manual 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Effector CD4+ T helper cells - % of CD4+ T helper cells HOM 6f:6m Manual 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Resting CD4+ NKT cells - % of CD4+ NKT cells HOM 6f:6m Manual 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Auditory Brain Stem Response / 12kHz-evoked ABR Threshold HOM 2f:6m 3.1386E-09 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / Eosinophil percentage HOM 7f:7m 0.0058361 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Bone marrow immunophenotyping / Immature B cells (Hardy fraction E) - % of B220+ HOM 5f:5m Manual 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Resting CD8+ T cells - % of CD45+ HOM 6f:6m Manual 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Follicular B cells - % of CD45+ HOM 6f:6m Manual 0.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Body Composition (DEXA lean/fat) / Bone Mineral Density (excluding skull) HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 1.5370E-11 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Pinna position HOM 7f:7m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Duoxa2tm1b(KOMP)Wtsi WTSI Hematology / Red blood cell count HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 6.0253E-22 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Paw coat/hair colour HOM 7f:7m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Duoxa2tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Hindpaw digit count HOM 7f:7m Fisher Exact Test framework 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Resting gd T cells - % of CD45+ HOM 6f:6m Manual 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Eye Morphology / Iris Pigmentation HOM 7f:7m Fisher Exact Test framework 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / CD4+ KLRG1+ alpha beta T cell percentage HOM 7f:7m 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Mature NK cells - % of lymphocytes HOM 5f:5m Manual 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Paw footpad skin colour HOM 7f:7m Fisher Exact Test framework 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / CD11b-high cDC - % of cDC HOM 5f:5m Manual 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Granulocytes - % of CD45+ HOM 5f:5m Manual 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Startle response HOM 7f:7m Fisher Exact Test framework 4.2784E-35 Success
Duoxa2tm1b(KOMP)Wtsi WTSI X-ray / Thoracic processes HOM 7f:7m Fisher Exact Test framework 2.3231E-14 Success
Duoxa2tm1b(KOMP)Wtsi WTSI X-ray / Humerus HOM 7f:7m Fisher Exact Test framework 3.3017E-34 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Effector CD8+ T cells - % of CD8+ HOM 6f:6m Manual 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Effector CD4+ NKT cells - % of CD4+ NKT cells HOM 6f:6m Manual 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Viability E14.5-E15.5 Secondary Screen / Outcome HOM f:m Supplied as data 0.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / NK cell number HOM 7f:7m 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Bone marrow immunophenotyping / Total B cells - % of CD45+ HOM 5f:5m Manual 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / CD5+ gd T cells - % of gd T cells HOM 6f:6m Manual 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI X-ray / Number of lumbar vertebrae HOM 7f:7m 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI X-ray / Lordosis HOM 7f:7m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Duoxa2tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Ventral skin colour HOM 7f:7m Fisher Exact Test framework 0.0035256 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Eosinophils - % of CD45+ HOM 5f:5m Manual 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Effector CD4+ NKT cells - % of CD45+ HOM 6f:6m Manual 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI X-ray / Ulna HOM 7f:7m Fisher Exact Test framework 9.0796E-33 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Memory B cells - % of B2 cells HOM 6f:6m Manual 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI X-ray / Sacral processes HOM 7f:7m Fisher Exact Test framework 2.8531E-38 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Resting CD4- NKT cells - % of CD4- NKT cells HOM 6f:6m Manual 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Tail coat/hair length HOM 7f:7m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Duoxa2tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Effector Treg cells - % of Treg HOM 6f:6m Manual 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / KLRG1+ CD8+ T cells - % of CD45+ HOM 6f:6m Manual 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Forepaw digit count HOM 7f:7m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Duoxa2tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Total DC - % of CD45+ HOM 3f:3m Manual 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Digit coat/hair presence HOM 7f:7m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Duoxa2tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / External genitalia size HOM 7f:7m Fisher Exact Test framework 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI X-ray / Number of caudal vertebrae HOM 7f:7m 0.011374 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / KLRG1+ NK cells - % of NK cells HOM 6f:6m Manual 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / NK cell percentage HOM 7f:7m 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI X-ray / Number of ribs left HOM 7f:7m 0.85012 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Memory B cells - % of CD45+ HOM 2f:2m Manual 1.0000 Not processed - Data analysis pending
Duoxa2tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Hindpaw nail colour HOM 7f:7m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Duoxa2tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Ventral coat/hair length HOM 7f:7m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Duoxa2tm1b(KOMP)Wtsi WTSI Body Composition (DEXA lean/fat) / Bone Area HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 7.2887E-101 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Total NK cells - % of CD45+ HOM 6f:6m Manual 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Total CD4+ T cells - % of ab T cells HOM 6f:6m Manual 0.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Transitional 2 B cells - % of B2 cells HOM 6f:6m Manual 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / IgD+ mature B cell number HOM 7f:7m 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Ear epidermis immunophenotyping / Average roundness of LC HOM 2f:2m Manual 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Total CD4- NKT cells - % of CD45+ HOM 6f:6m Manual 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Hindpaw digit morphology HOM 7f:7m Fisher Exact Test framework 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Resting CD4+ T helper cells - % of CD4+ T helper cells HOM 6f:6m Manual 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Tail skin colour HOM 7f:7m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Duoxa2tm1b(KOMP)Wtsi WTSI Bone marrow immunophenotyping / Mature B cells (Hardy fraction F) - % of B220+ HOM 5f:5m Manual 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Dorsal coat/hair presence HOM 7f:7m Fisher Exact Test framework 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Paw coat/hair presence HOM 7f:7m Fisher Exact Test framework 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Pinna morphology HOM 7f:7m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Duoxa2tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Hindpaw digit size HOM 7f:7m Fisher Exact Test framework 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Transitional 2 B cells - % of CD45+ HOM 6f:6m Manual 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Bone marrow immunophenotyping / Mature B cells (Hardy fraction F) - % of CD45+ HOM 5f:5m Manual 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / CD8+ KLRG1+ alpha beta T cell percentage HOM 7f:7m 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / KLRG1+ CD4+ T helper cells - % of CD45+ HOM 6f:6m Manual 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Effector CD8+ T cells - % of CD45+ HOM 6f:6m Manual 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / KLRG1+ CD4+ NKT cells - % of CD4+ NKT cells HOM 6f:6m Manual 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Bone marrow immunophenotyping / Pre-pro B cells (Hardy fraction A) - % of CD45+ HOM 5f:5m Manual 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI X-ray / Skull shape HOM 7f:7m Fisher Exact Test framework 7.5459E-23 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Total CD8+ T cells - % of ab T cells HOM 6f:6m Manual 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Forelimb HOM 7f:7m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Duoxa2tm1b(KOMP)Wtsi WTSI Ear epidermis immunophenotyping / Langerhans cell (LC) count HOM 2f:2m Manual 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Digit coat/hair colour HOM 7f:7m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Duoxa2tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Ly6C+ mature NK cells - % of lymphocytes HOM 5f:5m Manual 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / CD4+ CD25+ alpha beta regulatory T cell number HOM 7f:7m 0.32725 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Body Composition (DEXA lean/fat) / Lean mass HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 5.8881E-16 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Effector CD4- NKT cells - % of CD4- NKT cells HOM 6f:6m Manual 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Eye Morphology / Pupil Light Response HOM 7f:7m Fisher Exact Test framework 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / CD11b-low cDC - % of cDC HOM 5f:5m Manual 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Eye Morphology / Corneal opacity HOM 7f:7m Fisher Exact Test framework 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI X-ray / Number of pelvic vertebrae HOM 7f:7m 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Monocytes - % of CD45+ HOM 5f:5m Manual 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI X-ray / Shape of ribcage HOM 7f:7m Fisher Exact Test framework 5.4873E-24 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Tremor HOM 7f:7m Fisher Exact Test framework 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Hematology / White blood cell count HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 2.3082E-13 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Total CD4+ NKT cells - % of NKT cells HOM 6f:6m Manual 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Marginal zone B cells - % of B2 cells HOM 6f:6m Manual 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Eosinophils - % of CD45+ HOM 3f:3m Manual 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / KLRG1+ NK cells - % of NK cells HOM 6f:6m Manual 0.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Naive CD8+ T cells - % of CD8+ HOM 6f:6m Manual 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Plasma cells - % of CD45+ HOM 2f:2m Manual 1.0000 Not processed - Data analysis pending
Duoxa2tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Dorsal coat/hair appearance HOM 7f:7m Fisher Exact Test framework 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI X-ray / Number of thoracic vertebrae HOM 7f:7m 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Marginal zone precursor B cells - % of CD45+ HOM 6f:6m Manual 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Limb coat/hair colour HOM 7f:7m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Duoxa2tm1b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / KLRG1+ CD4+ T helper cells - % of CD4+ T helper cells HOM 6f:6m Manual 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / KLRG1+ CD4- NKT cells - % of CD4- NKT cells HOM 6f:6m Manual 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / B1a cells - % of CD45+ HOM 2f:2m Manual 1.0000 Not processed - Data analysis pending
Duoxa2tm1b(KOMP)Wtsi WTSI X-ray / Radius HOM 7f:7m Fisher Exact Test framework 2.3203E-32 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Memory B cells - % of CD45+ HOM 6f:6m Manual 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Tail coat/hair colour HOM 7f:7m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Duoxa2tm1b(KOMP)Wtsi WTSI Hematology / Mean platelet volume HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 5.0428E-08 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / NKT cell percentage HOM 7f:7m 0.32009 Success
Duoxa2tm1b(KOMP)Wtsi WTSI X-ray / Brachydactyly HOM 7f:7m Fisher Exact Test framework 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Total gd T cells - % of CD45+ HOM 6f:6m Manual 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Resting gd T cells - % of gd T cells HOM 6f:6m Manual 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Tail skin appearance HOM 7f:7m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Duoxa2tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Hindpaw nail morphology HOM 7f:7m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Duoxa2tm1b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Total CD4- NKT cells - % of NKT cells HOM 6f:6m Manual 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI X-ray / Scapulae HOM 7f:7m Fisher Exact Test framework 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Head coat/hair presence HOM 7f:7m Fisher Exact Test framework 4.1889E-05 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / Alpha beta T cell number HOM 7f:7m 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / CD4+ T helper cells - % of CD4+ HOM 6f:6m Manual 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Naive CD8+ T cells - % of CD45+ HOM 6f:6m Manual 0.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Forepaw digit fusion HOM 7f:7m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Duoxa2tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Plasma cells - % of B2 cells HOM 6f:6m Manual 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Immature NK cells - % of lymphocytes HOM 5f:5m Manual 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Eye Morphology / Retina (combined) HOM 7f:7m Not processed Success
Duoxa2tm1b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Resting Treg cells - % of CD45+ HOM 6f:6m Manual 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Pinna size HOM 7f:7m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Duoxa2tm1b(KOMP)Wtsi WTSI X-ray / Polysyndactylism HOM 7f:7m Fisher Exact Test framework 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Hematology / Hematocrit HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 1.2350E-09 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Memory B cells - % of B2 cells HOM 2f:2m Manual 1.0000 Not processed - Data analysis pending
Duoxa2tm1b(KOMP)Wtsi WTSI Bone marrow immunophenotyping / Immature B cells (Hardy fraction E) - % of CD45+ HOM 5f:5m Manual 0.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Vibrissae shape HOM 7f:7m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Duoxa2tm1b(KOMP)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / Ly6Clow monocyte number HOM 7f:7m 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Total Treg cells - % of CD45+ HOM 6f:6m Manual 0.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / CD4+ CD44+ CD62L- alpha beta effector T cell number HOM 7f:7m 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Eye Morphology / Pupil Dilation HOM 7f:7m Fisher Exact Test framework 0.015983 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / CD103+ CD11b-low cDC - % of CD11b-low cDC HOM 3f:3m Manual 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Body Composition (DEXA lean/fat) / Fat mass HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 1.1299E-10 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Bone marrow immunophenotyping / Pro-B cells (Hardy fraction C) - % of B220+ HOM 5f:5m Manual 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / KLRG1+ CD4+ NKT cells - % of CD45+ HOM 6f:6m Manual 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / KLRG1+ mature NK cell number HOM 7f:7m 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / KLRG1+ CD4- NKT cells - % of CD45+ HOM 6f:6m Manual 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Paw coat/hair appearance HOM 7f:7m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Duoxa2tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / KLRG1+ Treg cells - % of Treg HOM 6f:6m Manual 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Total Treg cells - % of CD45+ HOM 6f:6m Manual 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Transitional 1 B cells - % of CD45+ HOM 6f:6m Manual 0.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Indirect Calorimetry / Total water intake HOM 0f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.54716 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Forelimb size HOM 7f:7m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Duoxa2tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Tail elevation HOM 7f:7m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Duoxa2tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Dorsal skin colour HOM 7f:7m Fisher Exact Test framework 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Effector NK cells - % of NK cells HOM 6f:6m Manual 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Auditory Brain Stem Response / 18kHz-evoked ABR Threshold HOM 2f:6m 2.5835E-10 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Hindpaw morphology HOM 7f:7m Fisher Exact Test framework 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Total CD4- NKT cells - % of CD45+ HOM 6f:6m Manual 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / CD103+ CD11b-low cDC - % of CD11b-low cDC HOM 5f:5m Manual 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / B cell percentage HOM 7f:7m 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI X-ray / Clavicle HOM 7f:7m Fisher Exact Test framework 1.1006E-33 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Marginal zone B cells - % of CD45+ HOM 6f:6m Manual 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Total Treg cells - % of CD4+ HOM 6f:6m Manual 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Effector CD4- NKT cells - % of CD4- NKT cells HOM 6f:6m Manual 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Tail coat/hair colour pattern HOM 7f:7m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Duoxa2tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Late germinal centre B cells - % of GC cells HOM 6f:6m Manual 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI X-ray / Digit integrity HOM 7f:7m Fisher Exact Test framework 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Resting CD4- NKT cells - % of CD45+ HOM 6f:6m Manual 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Total CD4+ NKT cells - % of NKT cells HOM 6f:6m Manual 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Marginal zone precursor B cells - % of B2 cells HOM 6f:6m Manual 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Hindpaw nail length HOM 7f:7m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Duoxa2tm1b(KOMP)Wtsi WTSI Body Composition (DEXA lean/fat) / Fat/Body weight HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 1.6735E-07 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Dorsal coat/hair colour pattern HOM 7f:7m Fisher Exact Test framework 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Effector gd T cells - % of gd T cells HOM 6f:6m Manual 0.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI X-ray / Number of cervical vertebrae HOM 7f:7m 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Total B2 cells - % of CD45+ HOM 2f:2m Manual 1.0000 Not processed - Data analysis pending
Duoxa2tm1b(KOMP)Wtsi WTSI Eye Morphology / Eyelid closure HOM 7f:7m Fisher Exact Test framework 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Head coat/hair colour HOM 7f:7m Fisher Exact Test framework 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / KLRG1+ CD8+ T cells - % of CD45+ HOM 6f:6m Manual 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / Ly6Chigh monocyte number HOM 7f:7m 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Limb coat/hair colour pattern HOM 7f:7m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Duoxa2tm1b(KOMP)Wtsi WTSI Bone marrow immunophenotyping / Pre-B cells (Hardy fraction D) - % of CD45+ HOM 5f:5m Manual 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / Gamma delta T cell percentage HOM 7f:7m 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Effector Treg cells - % of CD45+ HOM 6f:6m Manual 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Late germinal centre B cells - % of CD45+ HOM 2f:2m Manual 1.0000 Not processed - Data analysis pending
Duoxa2tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Forepaw digit morphology HOM 7f:7m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Duoxa2tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Resting NK cells - % of NK cells HOM 6f:6m Manual 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / CD5+ gd T cells - % of CD45+ HOM 6f:6m Manual 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Hematology / Hemoglobin HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 2.3888E-07 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Ly6C+ immature NK cells - % of lymphocytes HOM 5f:5m Manual 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / Total T cell number HOM 7f:7m 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Plasma cells - % of B2 cells HOM 2f:2m Manual 1.0000 Not processed - Data analysis pending
Duoxa2tm1b(KOMP)Wtsi WTSI X-ray / Syndactylism HOM 7f:7m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Duoxa2tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Ly6C+ NKT cells - % of lymphocytes HOM 5f:5m Manual 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Total ab T cells - % of CD45+ HOM 6f:6m Manual 0.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Effector gd cells - % of CD45+ HOM 6f:6m Manual 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Forelimb morphology HOM 7f:7m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Duoxa2tm1b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / CD103+ CD11b-low cDC - % of CD45+ HOM 5f:5m Manual 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Eye Morphology / Optic Disc HOM 7f:7m Fisher Exact Test framework 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Eye Morphology / Narrow eye opening HOM 7f:7m Fisher Exact Test framework 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / CD11b-low cDC - % of cDC HOM 3f:3m Manual 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Heart Weight / Heart weight HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 5.5420E-11 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Vibrissae size HOM 7f:7m Fisher Exact Test framework 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Bone marrow immunophenotyping / Pre-B cells (Hardy fraction D) - % of B220+ HOM 5f:5m Manual 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Resting CD4+ NKT cells - % of CD4+ NKT cells HOM 6f:6m Manual 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Dorsal skin appearance HOM 7f:7m Fisher Exact Test framework 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Vibrissae colour HOM 7f:7m Fisher Exact Test framework 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / CD4+ KLRG1+ alpha beta T cell number HOM 7f:7m 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / IgD+ mature B cell percentage HOM 7f:7m 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Hindpaw footpad size HOM 7f:7m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Duoxa2tm1b(KOMP)Wtsi WTSI Eye Morphology / Pupil Shape HOM 7f:7m Fisher Exact Test framework 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI X-ray / Cervical processes HOM 7f:7m Fisher Exact Test framework 0.027560 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Effector NK cells - % of CD45+ HOM 6f:6m Manual 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Total CD8+ T cells - % of ab T cells HOM 6f:6m Manual 0.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Effector CD4+ NKT cells - % of CD4+ NKT cells HOM 6f:6m Manual 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Total NK cells - % of CD45+ HOM 6f:6m Manual 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Monocytes - % of CD45+ HOM 3f:3m Manual 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Resting CD8+ T cells - % of CD8+ HOM 6f:6m Manual 0.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Paw coat/hair colour pattern HOM 7f:7m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Duoxa2tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Hindpaw nail count HOM 7f:7m Fisher Exact Test framework 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Body Composition (DEXA lean/fat) / Lean/Body weight HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 2.5193E-06 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / CD8+ alpha beta T cell number HOM 7f:7m 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Bone marrow immunophenotyping / Plasma cells - % of CD45+ HOM 5f:5m Manual 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Auditory Brain Stem Response / Click-evoked ABR threshold HOM 2f:6m 1.0027E-06 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Eye Morphology / Synechia HOM 7f:7m Fisher Exact Test framework 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Resting NK cells - % of CD45+ HOM 6f:6m Manual 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Auditory Brain Stem Response / 24kHz-evoked ABR Threshold HOM 2f:6m 8.7370E-12 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / Monocyte percentage HOM 7f:7m 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Hindpaw HOM 7f:7m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Duoxa2tm1b(KOMP)Wtsi WTSI X-ray / Transitional vertebrae HOM 7f:7m Fisher Exact Test framework 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Early germinal centre B cells - % of CD45+ HOM 2f:2m Manual 1.0000 Not processed - Data analysis pending
Duoxa2tm1b(KOMP)Wtsi WTSI X-ray / Pelvis HOM 7f:7m Fisher Exact Test framework 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Late germinal centre B cells - % of CD45+ HOM 6f:6m Manual 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Pinna rotation HOM 7f:7m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Duoxa2tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Total ab T cells - % of CD45+ HOM 6f:6m Manual 0.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Eye Morphology / Eyelid morphology HOM 7f:7m Fisher Exact Test framework 1.6838E-06 Success
Duoxa2tm1b(KOMP)Wtsi WTSI X-ray / Shape of spine HOM 7f:7m Fisher Exact Test framework 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Hematology / Mean cell volume HOM 7f:7m Not processed 1.0000 FAILED - Insufficient variability in dependent variable 'IMPC_HEM_005_001' for MM/TF framework. Fisher Exact Test can be better way to do the analysis.
Duoxa2tm1b(KOMP)Wtsi WTSI Bone marrow immunophenotyping / Pro-B cells (Hardy fraction C) - % of CD45+ HOM 5f:5m Manual 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / CD11b-low cDC - % of CD45+ HOM 5f:5m Manual 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Effector CD8+ T cells - % of CD8+ HOM 6f:6m Manual 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / CD11b-high cDC - % of cDC HOM 3f:3m Manual 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Total NKT cells - % of CD45+ HOM 6f:6m Manual 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Pinna skin colour HOM 7f:7m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Duoxa2tm1b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / KLRG1+ gd T cells - % of gd T cells HOM 6f:6m Manual 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Positional passivity HOM 7f:7m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Duoxa2tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Forepaw nail length HOM 7f:7m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Duoxa2tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Head coat/hair colour pattern HOM 7f:7m Fisher Exact Test framework 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Forepaw HOM 7f:7m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Duoxa2tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Digit coat/hair length HOM 7f:7m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Duoxa2tm1b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Macrophages - % of CD45+ HOM 5f:5m Manual 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Total CD4+ T cells - % of CD45+ HOM 6f:6m Manual 0.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Eye Morphology / Retinal Blood Vessels HOM 7f:7m Fisher Exact Test framework 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Resting CD4- NKT cells - % of CD45+ HOM 6f:6m Manual 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Early germinal centre B cells - % of GC cells HOM 6f:6m Manual 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Total CD8+ T cells - % of CD45+ HOM 6f:6m Manual 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Total gd T cells - % of CD45+ HOM 6f:6m Manual 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / KLRG1+ CD4+ NKT cells - % of CD4+ NKT cells HOM 6f:6m Manual 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Vibrissae HOM 7f:7m Fisher Exact Test framework 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI X-ray / Mandibles HOM 7f:7m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Duoxa2tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Ventral coat/hair presence HOM 7f:7m Fisher Exact Test framework 1.2376E-10 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Pinna touch reflex HOM 7f:7m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Duoxa2tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Ly6C+ immature NK cells - % of immature NK cells HOM 5f:5m Manual 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Effector Treg cells - % of Treg HOM 6f:6m Manual 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Mouth morphology HOM 7f:7m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Duoxa2tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Granulocytes - % of CD45+ HOM 3f:3m Manual 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Effector CD4+ NKT cells - % of CD45+ HOM 6f:6m Manual 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI X-ray / Number of digits HOM 7f:7m 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Anti-nuclear antibody assay / ANA score HOM 0f:3m Manual 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Anti-nuclear antibody assay / ANA score HOM 3f:0m Manual 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / Total T cell percentage HOM 7f:7m 3.1280E-13 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Resting NK cells - % of CD45+ HOM 6f:6m Manual 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / KLRG1+ CD8+ T cells - % of CD8+ HOM 6f:6m Manual 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Limb coat/hair presence HOM 7f:7m Fisher Exact Test framework 1.3913E-05 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / Ly6Chigh monocyte percentage HOM 7f:7m 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI DSS Histology / Average histology score HOM 2f:2m Not processed 1.0000 FAILED - Not enough mutant or control data
Duoxa2tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Incisors HOM 7f:7m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Duoxa2tm1b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / KLRG1+ NK cells - % of CD45+ HOM 6f:6m Manual 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Hindpaw size HOM 7f:7m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Duoxa2tm1b(KOMP)Wtsi WTSI Bone marrow immunophenotyping / Pro-B cells (Hardy fraction B) - % of CD45+ HOM 5f:5m Manual 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Plasma cells - % of CD45+ HOM 6f:6m Manual 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Anti-nuclear antibody assay / ANA classification HOM 0f:3m Manual 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Anti-nuclear antibody assay / ANA classification HOM 3f:0m Manual 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Eye Morphology / Eye Hemorrhage or Blood Presence HOM 7f:7m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Duoxa2tm1b(KOMP)Wtsi WTSI X-ray / Teeth HOM 7f:7m Fisher Exact Test framework 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Paw coat/hair length HOM 7f:7m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Duoxa2tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Immature NK cells - % of NK cells HOM 5f:5m Manual 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / CD4+ T helper cells - % of CD45+ HOM 6f:6m Manual 0.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / CD4+ alpha beta T cell number HOM 7f:7m 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Total NKT cells - % of CD45+ HOM 6f:6m Manual 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Ear epidermis immunophenotyping / DETC coverage HOM 2f:2m Manual 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Eye Morphology / Fusion between cornea and lens HOM 7f:7m Fisher Exact Test framework 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Hematology / Mean corpuscular hemoglobin HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 3.4267E-37 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Total CD4+ T cells - % of CD45+ HOM 6f:6m Manual 0.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Tail coat/hair presence HOM 7f:7m Fisher Exact Test framework 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Forepaw size HOM 7f:7m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Duoxa2tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / KLRG1+ NK cells - % of CD45+ HOM 6f:6m Manual 0.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Bone marrow immunophenotyping / T cells - % of CD45+ HOM 5f:5m Manual 0.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Limb grasping HOM 7f:7m Fisher Exact Test framework 0.010542 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Conventional DC (cDC) - % of DC HOM 3f:3m Manual 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI X-ray / Fusion of ribs HOM 7f:7m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Duoxa2tm1b(KOMP)Wtsi WTSI Body Composition (DEXA lean/fat) / BMC/Body weight HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.00063648 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / KLRG1+ gd T cells - % of gd T cells HOM 6f:6m Manual 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Head coat/hair appearance HOM 7f:7m Fisher Exact Test framework 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Forepaw nail count HOM 7f:7m Fisher Exact Test framework 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / Neutrophil number HOM 7f:7m 0.30558 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Eye Morphology / Retinal Blood Vessels Structure HOM 7f:7m Fisher Exact Test framework 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / CD11b-high cDC - % of CD45+ HOM 5f:5m Manual 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Germinal centre B cells - % of CD45+ HOM 2f:2m Manual 1.0000 Not processed - Data analysis pending
Duoxa2tm1b(KOMP)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / CD8+ CD44+ CD62L- alpha beta effector T cell number HOM 7f:7m 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI X-ray / Joints HOM 7f:7m Fisher Exact Test framework 2.7456E-28 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Resting CD8+ T cells - % of CD8+ HOM 6f:6m Manual 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / KLRG1+ Treg cells - % of CD45+ HOM 6f:6m Manual 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Pinna skin appearance HOM 7f:7m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Duoxa2tm1b(KOMP)Wtsi WTSI X-ray / Fusion of processes HOM 7f:7m Fisher Exact Test framework 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Hematology / Red blood cell distribution width HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 3.1395E-09 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Snout size HOM 7f:7m Fisher Exact Test framework 9.6953E-22 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Total CD4+ NKT cells - % of CD45+ HOM 6f:6m Manual 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / Alpha beta T cell percentage HOM 7f:7m 2.0278E-11 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Ear epidermis immunophenotyping / Average no of branches on LC HOM 2f:2m Manual 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / CD5+ gd T cells - % of CD45+ HOM 6f:6m Manual 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Effector CD4- NKT cells - % of CD45+ HOM 6f:6m Manual 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Bone marrow immunophenotyping / Pro-B cells (Hardy fraction B) - % of B220+ HOM 5f:5m Manual 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Total T cells - % of CD45+ HOM 6f:6m Manual 0.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Total Treg cells - % of CD4+ HOM 6f:6m Manual 1.0000 Success
Duoxa2tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Dorsal coat/hair length HOM 7f:7m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK

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