Med11tm1.1(KOMP)Vlcg
|
JAX
|
Open Field - centre start / Whole arena average speed
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.279
|
Successful |
Med11tm1.1(KOMP)Vlcg
|
JAX
|
Electroconvulsive Threshold Testing / mA threshold inducing clonic seizure
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.711
|
Successful |
Med11tm1.1(KOMP)Vlcg
|
JAX
|
Hole-board Exploration / Holepoke sequence
|
HET
|
297f:311m
|
|
|
NotProcessed |
Med11tm1.1(KOMP)Vlcg
|
JAX
|
Sleep Wake / Light sleep bout lengths standard deviation
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.143
|
Successful |
Med11tm1.1(KOMP)Vlcg
|
JAX
|
Combined SHIRPA and Dysmorphology / Activity (body position)
|
HET
|
7f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Med11tm1.1(KOMP)Vlcg
|
JAX
|
Combined SHIRPA and Dysmorphology / Head bobbing
|
HET
|
7f:8m
|
|
|
NotProcessed |
Med11tm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP1
|
HET
|
8f:8m
|
|
|
NotProcessed |
Med11tm1.1(KOMP)Vlcg
|
JAX
|
Light-Dark Test / Percent time in light
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.229
|
Successful |
Med11tm1.1(KOMP)Vlcg
|
JAX
|
Open Field - centre start / Center average speed
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.732
|
Successful |
Med11tm1.1(KOMP)Vlcg
|
JAX
|
Combined SHIRPA and Dysmorphology / Trunk curl
|
HET
|
7f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Med11tm1.1(KOMP)Vlcg
|
JAX
|
Open Field - centre start / Center permanence time
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.458
|
Successful |
Med11tm1.1(KOMP)Vlcg
|
JAX
|
Light-Dark Test / Side changes
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.954
|
Successful |
Med11tm1.1(KOMP)Vlcg
|
JAX
|
Gross Morphology Embryo E12.5 / Midbrain morphology
|
HET
|
21f:3m
|
Supplied as data
|
1.00
|
Successful |
Med11tm1.1(KOMP)Vlcg
|
JAX
|
Hole-board Exploration / Total holepokes
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.129
|
Successful |
Med11tm1.1(KOMP)Vlcg
|
JAX
|
Sleep Wake / Dark sleep bout lengths mean
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.244
|
Successful |
Med11tm1.1(KOMP)Vlcg
|
JAX
|
Combined SHIRPA and Dysmorphology / Unexpected behaviors
|
HET
|
7f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Med11tm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP2
|
HET
|
8f:8m
|
|
|
NotProcessed |
Med11tm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - Global
|
HET
|
8f:8m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.337
|
Successful |
Med11tm1.1(KOMP)Vlcg
|
JAX
|
Light-Dark Test / Light side time spent
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.462
|
Successful |
Med11tm1.1(KOMP)Vlcg
|
JAX
|
Gross Morphology Embryo E12.5 / Neural Tube Closure
|
HET
|
21f:3m
|
Supplied as data
|
1.00
|
Successful |
Med11tm1.1(KOMP)Vlcg
|
JAX
|
Open Field - centre start / Periphery distance travelled
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.594
|
Successful |
Med11tm1.1(KOMP)Vlcg
|
JAX
|
Gross Morphology Embryo E12.5 / Forebrain morphology
|
HET
|
21f:3m
|
Supplied as data
|
1.00
|
Successful |
Med11tm1.1(KOMP)Vlcg
|
JAX
|
Open Field - centre start / Whole arena resting time
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.407
|
Successful |
Med11tm1.1(KOMP)Vlcg
|
JAX
|
Combined SHIRPA and Dysmorphology / Aggression
|
HET
|
7f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Med11tm1.1(KOMP)Vlcg
|
JAX
|
Open Field - centre start / Number of Rears
|
HET
|
32f:32m
|
|
|
NotProcessed |
Med11tm1.1(KOMP)Vlcg
|
JAX
|
Light-Dark Test / Time mobile light side
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.961
|
Successful |
Med11tm1.1(KOMP)Vlcg
|
JAX
|
Grip Strength / Forelimb grip strength measurement mean
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.109
|
Successful |
Med11tm1.1(KOMP)Vlcg
|
JAX
|
Combined SHIRPA and Dysmorphology / Startle response
|
HET
|
7f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Med11tm1.1(KOMP)Vlcg
|
JAX
|
Sleep Wake / Breath rate during sleep standard deviation
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0113
|
Successful |
Med11tm1.1(KOMP)Vlcg
|
JAX
|
Open Field - centre start / Percentage center time
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.458
|
Successful |
Med11tm1.1(KOMP)Vlcg
|
JAX
|
Gross Morphology Embryo E9.5 / Midbrain
|
HOM
|
1f:1m
|
Supplied as data
|
1.00
|
Successful |
Med11tm1.1(KOMP)Vlcg
|
JAX
|
Gross Morphology Embryo E9.5 / Midbrain
|
HET
|
9f:7m
|
Supplied as data
|
1.00
|
Successful |
Med11tm1.1(KOMP)Vlcg
|
JAX
|
Open Field - centre start / Distance travelled
|
HET
|
32f:32m
|
|
|
NotProcessed |
Med11tm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - BN
|
HET
|
8f:8m
|
|
|
NotProcessed |
Med11tm1.1(KOMP)Vlcg
|
JAX
|
Gross Morphology Embryo E12.5 / Hindbrain morphology
|
HET
|
21f:3m
|
Supplied as data
|
1.00
|
Successful |
Med11tm1.1(KOMP)Vlcg
|
JAX
|
Combined SHIRPA and Dysmorphology / Vocalization
|
HET
|
7f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Med11tm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP3_S
|
HET
|
8f:8m
|
|
|
NotProcessed |
Med11tm1.1(KOMP)Vlcg
|
JAX
|
Combined SHIRPA and Dysmorphology / Touch escape
|
HET
|
7f:8m
|
|
|
NotProcessed |
Med11tm1.1(KOMP)Vlcg
|
JAX
|
Tail Suspension / Time immobile
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.329
|
Successful |
Med11tm1.1(KOMP)Vlcg
|
JAX
|
Sleep Wake / Sleep daily percent
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.887
|
Successful |
Med11tm1.1(KOMP)Vlcg
|
JAX
|
Light-Dark Test / Dark side time spent
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.462
|
Successful |
Med11tm1.1(KOMP)Vlcg
|
JAX
|
Grip Strength / Forelimb and hindlimb grip strength measurement mean
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.238
|
Successful |
Med11tm1.1(KOMP)Vlcg
|
JAX
|
Sleep Wake / Sleep light phase percent
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.0527
|
Successful |
Med11tm1.1(KOMP)Vlcg
|
JAX
|
Open Field - centre start / Number of rears - total
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.0106
|
Successful |
Med11tm1.1(KOMP)Vlcg
|
JAX
|
Grip Strength / Forelimb grip strength measurement
|
HET
|
24f:24m
|
|
|
NotProcessed |
Med11tm1.1(KOMP)Vlcg
|
JAX
|
Rotarod / Latency to fall
|
HET
|
40f:40m
|
|
|
NotProcessed |
Med11tm1.1(KOMP)Vlcg
|
JAX
|
Tail Suspension / Latency to immobility
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.247
|
Successful |
Med11tm1.1(KOMP)Vlcg
|
JAX
|
Sleep Wake / Peak wake with respect to dark onset median
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.675
|
Successful |
Med11tm1.1(KOMP)Vlcg
|
JAX
|
Gross Morphology Embryo E9.5 / Neural tube closure
|
HOM
|
1f:1m
|
Supplied as data
|
1.00
|
Successful |
Med11tm1.1(KOMP)Vlcg
|
JAX
|
Gross Morphology Embryo E9.5 / Neural tube closure
|
HET
|
9f:7m
|
Supplied as data
|
1.00
|
Successful |
Med11tm1.1(KOMP)Vlcg
|
JAX
|
Grip Strength / Forelimb grip strength normalised against body weight
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.108
|
Successful |
Med11tm1.1(KOMP)Vlcg
|
JAX
|
Combined SHIRPA and Dysmorphology / Locomotor activity
|
HET
|
7f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.618
|
Successful |
Med11tm1.1(KOMP)Vlcg
|
JAX
|
Eye Morphology / Optic Disc
|
HET
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Med11tm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP2_S
|
HET
|
8f:8m
|
|
|
NotProcessed |
Med11tm1.1(KOMP)Vlcg
|
JAX
|
Combined SHIRPA and Dysmorphology / Tail elevation
|
HET
|
7f:8m
|
|
|
NotProcessed |
Med11tm1.1(KOMP)Vlcg
|
JAX
|
Open Field - centre start / Periphery average speed
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.365
|
Successful |
Med11tm1.1(KOMP)Vlcg
|
JAX
|
Light-Dark Test / Time mobile dark side
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.454
|
Successful |
Med11tm1.1(KOMP)Vlcg
|
JAX
|
Light-Dark Test / Fecal boli
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.135
|
Successful |
Med11tm1.1(KOMP)Vlcg
|
JAX
|
Combined SHIRPA and Dysmorphology / Contact righting
|
HET
|
7f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Med11tm1.1(KOMP)Vlcg
|
JAX
|
Sleep Wake / Sleep dark phase percent
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.210
|
Successful |
Med11tm1.1(KOMP)Vlcg
|
JAX
|
Grip Strength / Forelimb and hindlimb grip strength normalised against body weight
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.392
|
Successful |
Med11tm1.1(KOMP)Vlcg
|
JAX
|
Grip Strength / Forelimb and hindlimb grip strength measurement
|
HET
|
24f:24m
|
|
|
NotProcessed |
Med11tm1.1(KOMP)Vlcg
|
JAX
|
Open Field - centre start / Distance travelled - total
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.281
|
Successful |
Med11tm1.1(KOMP)Vlcg
|
JAX
|
Gross Morphology Embryo E9.5 / Forebrain
|
HET
|
9f:7m
|
Supplied as data
|
1.00
|
Successful |
Med11tm1.1(KOMP)Vlcg
|
JAX
|
Gross Morphology Embryo E9.5 / Forebrain
|
HOM
|
1f:1m
|
Supplied as data
|
1.00
|
Successful |
Med11tm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP1_S
|
HET
|
8f:8m
|
|
|
NotProcessed |
Med11tm1.1(KOMP)Vlcg
|
JAX
|
Sleep Wake / Breath rate during sleep mean
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.00148
|
Successful |
Med11tm1.1(KOMP)Vlcg
|
JAX
|
Open Field - centre start / Periphery permanence time
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.458
|
Successful |
Med11tm1.1(KOMP)Vlcg
|
JAX
|
Combined SHIRPA and Dysmorphology / Gait
|
HET
|
7f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Med11tm1.1(KOMP)Vlcg
|
JAX
|
Rotarod / Learning slope
|
HET
|
8f:8m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.00209
|
Successful |
Med11tm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI1
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.252
|
Successful |
Med11tm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP4
|
HET
|
8f:8m
|
|
|
NotProcessed |
Med11tm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI3
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.0641
|
Successful |
Med11tm1.1(KOMP)Vlcg
|
JAX
|
Sleep Wake / Sleep bout lengths mean
|
HET
|
8f:8m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.268
|
Successful |
Med11tm1.1(KOMP)Vlcg
|
JAX
|
Combined SHIRPA and Dysmorphology / Tremor
|
HET
|
7f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Med11tm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI2
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.0678
|
Successful |
Med11tm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - S
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.0482
|
Successful |
Med11tm1.1(KOMP)Vlcg
|
JAX
|
Light-Dark Test / Latency to first transition into dark
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.600
|
Successful |
Med11tm1.1(KOMP)Vlcg
|
JAX
|
Rotarod / Learning difference
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.0123
|
Successful |
Med11tm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI4
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.524
|
Successful |
Med11tm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP3
|
HET
|
8f:8m
|
|
|
NotProcessed |
Med11tm1.1(KOMP)Vlcg
|
JAX
|
Sleep Wake / Dark sleep bout lengths standard deviation
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.653
|
Successful |
Med11tm1.1(KOMP)Vlcg
|
JAX
|
Eye Morphology / Pupil Light Response
|
HET
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Med11tm1.1(KOMP)Vlcg
|
JAX
|
Combined SHIRPA and Dysmorphology / Limb grasp
|
HET
|
7f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Med11tm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP4_S
|
HET
|
8f:8m
|
|
|
NotProcessed |
Med11tm1.1(KOMP)Vlcg
|
JAX
|
Sleep Wake / Light sleep bout lengths mean
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.581
|
Successful |
Med11tm1.1(KOMP)Vlcg
|
JAX
|
Combined SHIRPA and Dysmorphology / Transfer arousal
|
HET
|
7f:8m
|
|
|
NotProcessed |
Med11tm1.1(KOMP)Vlcg
|
JAX
|
Sleep Wake / Sleep bout lengths standard deviation
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.212
|
Successful |
Med11tm1.1(KOMP)Vlcg
|
JAX
|
Light-Dark Test / Percent time in dark
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.229
|
Successful |
Med11tm1.1(KOMP)Vlcg
|
JAX
|
Gross Morphology Embryo E9.5 / Neural tube morphology
|
HET
|
9f:7m
|
Supplied as data
|
1.00
|
Successful |
Med11tm1.1(KOMP)Vlcg
|
JAX
|
Gross Morphology Embryo E9.5 / Neural tube morphology
|
HOM
|
1f:m
|
Supplied as data
|
1.00
|
Successful |
Med11tm1.1(KOMP)Vlcg
|
JAX
|
Rotarod / Average duration
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.0402
|
Successful |
Med11tm1.1(KOMP)Vlcg
|
JAX
|
Open Field - centre start / Center distance travelled
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.105
|
Successful |