Actr8tm1.1(KOMP)Vlcg
|
JAX
|
Open Field - centre start / Whole arena average speed
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.000876
|
Successful |
Actr8tm1.1(KOMP)Vlcg
|
JAX
|
Electroconvulsive Threshold Testing / mA threshold inducing clonic seizure
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.149
|
Successful |
Actr8tm1.1(KOMP)Vlcg
|
JAX
|
Hole-board Exploration / Holepoke sequence
|
HET
|
427f:328m
|
|
|
NotProcessed |
Actr8tm1.1(KOMP)Vlcg
|
JAX
|
Sleep Wake / Light sleep bout lengths standard deviation
|
HET
|
2f:m
|
|
|
NotProcessed |
Actr8tm1.1(KOMP)Vlcg
|
JAX
|
Combined SHIRPA and Dysmorphology / Activity (body position)
|
HET
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Actr8tm1.1(KOMP)Vlcg
|
JAX
|
Combined SHIRPA and Dysmorphology / Head bobbing
|
HET
|
8f:8m
|
|
|
NotProcessed |
Actr8tm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP1
|
HET
|
4f:4m
|
|
|
NotProcessed |
Actr8tm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP1
|
HET
|
4f:4m
|
|
|
NotProcessed |
Actr8tm1.1(KOMP)Vlcg
|
JAX
|
Light-Dark Test / Percent time in light
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.267
|
Successful |
Actr8tm1.1(KOMP)Vlcg
|
JAX
|
Open Field - centre start / Center average speed
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.619
|
Successful |
Actr8tm1.1(KOMP)Vlcg
|
JAX
|
Combined SHIRPA and Dysmorphology / Trunk curl
|
HET
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Actr8tm1.1(KOMP)Vlcg
|
JAX
|
Open Field - centre start / Center permanence time
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0208
|
Successful |
Actr8tm1.1(KOMP)Vlcg
|
JAX
|
Light-Dark Test / Side changes
|
HET
|
8f:8m
|
Linear Model Using Generalized Least Squares framework, GLS, including Weight
|
0.0316
|
Successful |
Actr8tm1.1(KOMP)Vlcg
|
JAX
|
Gross Morphology Embryo E12.5 / Midbrain morphology
|
HET
|
4f:4m
|
Supplied as data
|
1.00
|
Successful |
Actr8tm1.1(KOMP)Vlcg
|
JAX
|
Hole-board Exploration / Total holepokes
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.0688
|
Successful |
Actr8tm1.1(KOMP)Vlcg
|
JAX
|
Sleep Wake / Dark sleep bout lengths mean
|
HET
|
2f:m
|
|
|
NotProcessed |
Actr8tm1.1(KOMP)Vlcg
|
JAX
|
Combined SHIRPA and Dysmorphology / Unexpected behaviors
|
HET
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Actr8tm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP2
|
HET
|
4f:4m
|
|
|
NotProcessed |
Actr8tm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP2
|
HET
|
4f:4m
|
|
|
NotProcessed |
Actr8tm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - Global
|
HET
|
4f:4m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.589
|
Successful |
Actr8tm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - Global
|
HET
|
4f:4m
|
Linear Mixed Model framework, LME, not including Weight
|
0.640
|
Successful |
Actr8tm1.1(KOMP)Vlcg
|
JAX
|
Light-Dark Test / Light side time spent
|
HET
|
8f:8m
|
Linear Model Using Generalized Least Squares framework, GLS, including Weight
|
0.942
|
Successful |
Actr8tm1.1(KOMP)Vlcg
|
JAX
|
Gross Morphology Embryo E12.5 / Neural Tube Closure
|
HET
|
4f:4m
|
Supplied as data
|
1.00
|
Successful |
Actr8tm1.1(KOMP)Vlcg
|
JAX
|
Open Field - centre start / Periphery distance travelled
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0279
|
Successful |
Actr8tm1.1(KOMP)Vlcg
|
JAX
|
Gross Morphology Embryo E12.5 / Forebrain morphology
|
HET
|
4f:4m
|
Supplied as data
|
1.00
|
Successful |
Actr8tm1.1(KOMP)Vlcg
|
JAX
|
Open Field - centre start / Whole arena resting time
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.00433
|
Successful |
Actr8tm1.1(KOMP)Vlcg
|
JAX
|
Combined SHIRPA and Dysmorphology / Aggression
|
HET
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Actr8tm1.1(KOMP)Vlcg
|
JAX
|
Open Field - centre start / Number of Rears
|
HET
|
32f:32m
|
|
|
NotProcessed |
Actr8tm1.1(KOMP)Vlcg
|
JAX
|
Light-Dark Test / Time mobile light side
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.0937
|
Successful |
Actr8tm1.1(KOMP)Vlcg
|
JAX
|
Grip Strength / Forelimb grip strength measurement mean
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.236
|
Successful |
Actr8tm1.1(KOMP)Vlcg
|
JAX
|
Combined SHIRPA and Dysmorphology / Startle response
|
HET
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Actr8tm1.1(KOMP)Vlcg
|
JAX
|
Sleep Wake / Breath rate during sleep standard deviation
|
HET
|
2f:m
|
|
|
NotProcessed |
Actr8tm1.1(KOMP)Vlcg
|
JAX
|
Open Field - centre start / Percentage center time
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0208
|
Successful |
Actr8tm1.1(KOMP)Vlcg
|
JAX
|
Gross Morphology Embryo E9.5 / Midbrain
|
HET
|
10f:10m
|
Supplied as data
|
1.00
|
Successful |
Actr8tm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - BN
|
HET
|
4f:4m
|
|
|
NotProcessed |
Actr8tm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - BN
|
HET
|
4f:4m
|
|
|
NotProcessed |
Actr8tm1.1(KOMP)Vlcg
|
JAX
|
Open Field - centre start / Distance travelled
|
HET
|
32f:32m
|
|
|
NotProcessed |
Actr8tm1.1(KOMP)Vlcg
|
JAX
|
Gross Morphology Embryo E12.5 / Hindbrain morphology
|
HET
|
4f:4m
|
Supplied as data
|
1.00
|
Successful |
Actr8tm1.1(KOMP)Vlcg
|
JAX
|
Combined SHIRPA and Dysmorphology / Vocalization
|
HET
|
8f:8m
|
Fisher Exact Test framework
|
0.619
|
Successful |
Actr8tm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP3_S
|
HET
|
4f:4m
|
|
|
NotProcessed |
Actr8tm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP3_S
|
HET
|
4f:4m
|
|
|
NotProcessed |
Actr8tm1.1(KOMP)Vlcg
|
JAX
|
Tail Suspension / Time immobile
|
HET
|
8f:8m
|
Linear Model Using Generalized Least Squares framework, GLS, including Weight
|
0.139
|
Successful |
Actr8tm1.1(KOMP)Vlcg
|
JAX
|
Sleep Wake / Sleep daily percent
|
HET
|
2f:m
|
|
|
NotProcessed |
Actr8tm1.1(KOMP)Vlcg
|
JAX
|
Light-Dark Test / Dark side time spent
|
HET
|
8f:8m
|
Linear Model Using Generalized Least Squares framework, GLS, including Weight
|
0.942
|
Successful |
Actr8tm1.1(KOMP)Vlcg
|
JAX
|
Grip Strength / Forelimb and hindlimb grip strength measurement mean
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.647
|
Successful |
Actr8tm1.1(KOMP)Vlcg
|
JAX
|
Sleep Wake / Sleep light phase percent
|
HET
|
2f:m
|
|
|
NotProcessed |
Actr8tm1.1(KOMP)Vlcg
|
JAX
|
Open Field - centre start / Number of rears - total
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.143
|
Successful |
Actr8tm1.1(KOMP)Vlcg
|
JAX
|
Grip Strength / Forelimb grip strength measurement
|
HET
|
24f:24m
|
|
|
NotProcessed |
Actr8tm1.1(KOMP)Vlcg
|
JAX
|
Sleep Wake / Peak wake with respect to dark onset median
|
HET
|
2f:m
|
|
|
NotProcessed |
Actr8tm1.1(KOMP)Vlcg
|
JAX
|
Rotarod / Latency to fall
|
HET
|
40f:40m
|
|
|
NotProcessed |
Actr8tm1.1(KOMP)Vlcg
|
JAX
|
Tail Suspension / Latency to immobility
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.711
|
Successful |
Actr8tm1.1(KOMP)Vlcg
|
JAX
|
Gross Morphology Embryo E9.5 / Neural tube closure
|
HET
|
10f:10m
|
Supplied as data
|
1.00
|
Successful |
Actr8tm1.1(KOMP)Vlcg
|
JAX
|
Grip Strength / Forelimb grip strength normalised against body weight
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0700
|
Successful |
Actr8tm1.1(KOMP)Vlcg
|
JAX
|
Combined SHIRPA and Dysmorphology / Locomotor activity
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.909
|
Successful |
Actr8tm1.1(KOMP)Vlcg
|
JAX
|
Eye Morphology / Optic Disc
|
HET
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Actr8tm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP2_S
|
HET
|
4f:4m
|
|
|
NotProcessed |
Actr8tm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP2_S
|
HET
|
4f:4m
|
|
|
NotProcessed |
Actr8tm1.1(KOMP)Vlcg
|
JAX
|
Combined SHIRPA and Dysmorphology / Tail elevation
|
HET
|
8f:8m
|
|
|
NotProcessed |
Actr8tm1.1(KOMP)Vlcg
|
JAX
|
Open Field - centre start / Periphery average speed
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.000508
|
Successful |
Actr8tm1.1(KOMP)Vlcg
|
JAX
|
Light-Dark Test / Time mobile dark side
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.108
|
Successful |
Actr8tm1.1(KOMP)Vlcg
|
JAX
|
Light-Dark Test / Fecal boli
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.150
|
Successful |
Actr8tm1.1(KOMP)Vlcg
|
JAX
|
Combined SHIRPA and Dysmorphology / Contact righting
|
HET
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Actr8tm1.1(KOMP)Vlcg
|
JAX
|
Sleep Wake / Sleep dark phase percent
|
HET
|
2f:m
|
|
|
NotProcessed |
Actr8tm1.1(KOMP)Vlcg
|
JAX
|
Grip Strength / Forelimb and hindlimb grip strength normalised against body weight
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.617
|
Successful |
Actr8tm1.1(KOMP)Vlcg
|
JAX
|
Grip Strength / Forelimb and hindlimb grip strength measurement
|
HET
|
24f:24m
|
|
|
NotProcessed |
Actr8tm1.1(KOMP)Vlcg
|
JAX
|
Open Field - centre start / Distance travelled - total
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.000844
|
Successful |
Actr8tm1.1(KOMP)Vlcg
|
JAX
|
Gross Morphology Embryo E9.5 / Forebrain
|
HET
|
10f:10m
|
Supplied as data
|
1.00
|
Successful |
Actr8tm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP1_S
|
HET
|
4f:4m
|
|
|
NotProcessed |
Actr8tm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP1_S
|
HET
|
4f:4m
|
|
|
NotProcessed |
Actr8tm1.1(KOMP)Vlcg
|
JAX
|
Sleep Wake / Breath rate during sleep mean
|
HET
|
2f:m
|
|
|
NotProcessed |
Actr8tm1.1(KOMP)Vlcg
|
JAX
|
Open Field - centre start / Periphery permanence time
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0209
|
Successful |
Actr8tm1.1(KOMP)Vlcg
|
JAX
|
Combined SHIRPA and Dysmorphology / Gait
|
HET
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Actr8tm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI1
|
HET
|
4f:4m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0701
|
Successful |
Actr8tm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI1
|
HET
|
4f:4m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.961
|
Successful |
Actr8tm1.1(KOMP)Vlcg
|
JAX
|
Rotarod / Learning slope
|
HET
|
8f:8m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.852
|
Successful |
Actr8tm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI3
|
HET
|
4f:4m
|
Linear Mixed Model framework, LME, including Weight
|
0.212
|
Successful |
Actr8tm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI3
|
HET
|
4f:4m
|
Linear Mixed Model framework, LME, not including Weight
|
0.239
|
Successful |
Actr8tm1.1(KOMP)Vlcg
|
JAX
|
Sleep Wake / Sleep bout lengths mean
|
HET
|
2f:m
|
|
|
NotProcessed |
Actr8tm1.1(KOMP)Vlcg
|
JAX
|
Combined SHIRPA and Dysmorphology / Tremor
|
HET
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Actr8tm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI2
|
HET
|
4f:4m
|
Linear Mixed Model framework, LME, not including Weight
|
0.521
|
Successful |
Actr8tm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI2
|
HET
|
4f:4m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.824
|
Successful |
Actr8tm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - S
|
HET
|
4f:4m
|
Linear Mixed Model framework, LME, not including Weight
|
0.000538
|
Successful |
Actr8tm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - S
|
HET
|
4f:4m
|
Linear Mixed Model framework, LME, including Weight
|
0.346
|
Successful |
Actr8tm1.1(KOMP)Vlcg
|
JAX
|
Light-Dark Test / Latency to first transition into dark
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.358
|
Successful |
Actr8tm1.1(KOMP)Vlcg
|
JAX
|
Rotarod / Learning difference
|
HET
|
8f:8m
|
Linear Model Using Generalized Least Squares framework, GLS, including Weight
|
0.463
|
Successful |
Actr8tm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP3
|
HET
|
4f:4m
|
|
|
NotProcessed |
Actr8tm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP3
|
HET
|
4f:4m
|
|
|
NotProcessed |
Actr8tm1.1(KOMP)Vlcg
|
JAX
|
Sleep Wake / Dark sleep bout lengths standard deviation
|
HET
|
2f:m
|
|
|
NotProcessed |
Actr8tm1.1(KOMP)Vlcg
|
JAX
|
Combined SHIRPA and Dysmorphology / Limb grasp
|
HET
|
8f:8m
|
Fisher Exact Test framework
|
0.390
|
Successful |
Actr8tm1.1(KOMP)Vlcg
|
JAX
|
Eye Morphology / Pupil Light Response
|
HET
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Actr8tm1.1(KOMP)Vlcg
|
JAX
|
Sleep Wake / Light sleep bout lengths mean
|
HET
|
2f:m
|
|
|
NotProcessed |
Actr8tm1.1(KOMP)Vlcg
|
JAX
|
Combined SHIRPA and Dysmorphology / Transfer arousal
|
HET
|
8f:8m
|
|
|
NotProcessed |
Actr8tm1.1(KOMP)Vlcg
|
JAX
|
Sleep Wake / Sleep bout lengths standard deviation
|
HET
|
2f:m
|
|
|
NotProcessed |
Actr8tm1.1(KOMP)Vlcg
|
JAX
|
Light-Dark Test / Percent time in dark
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.267
|
Successful |
Actr8tm1.1(KOMP)Vlcg
|
JAX
|
Rotarod / Average duration
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.940
|
Successful |
Actr8tm1.1(KOMP)Vlcg
|
JAX
|
Open Field - centre start / Center distance travelled
|
HET
|
8f:8m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
8.85×10-05
|
Successful |