Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Tail - thickness
|
HOM
|
7f:8m
|
|
|
NotProcessed |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Forelimb digit - size
|
HOM
|
7f:8m
|
|
|
NotProcessed |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Clinical Chemistry / Alanine aminotransferase
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.213
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Eye Morphology / Ophthalmoscope Observation
|
HOM
|
2f:5m
|
|
|
NotProcessed |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Coat - hair distribution - back
|
HOM
|
7f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Echo / LVPWd
|
HOM
|
7f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.340
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Eye Morphology / Bulging eye
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Forelimb nail - shape
|
HOM
|
7f:8m
|
|
|
NotProcessed |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Electrocardiogram (ECG) / RR
|
HOM
|
7f:8m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.632
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Skin texture - whole body
|
HOM
|
7f:8m
|
|
|
NotProcessed |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Eye Morphology / Left vitreous humour thickness
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
2.16×10-05
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Trunk curl
|
HOM
|
7f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Clinical Chemistry / Creatinine
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.308
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Eye Morphology / Iris/Pupil
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
0.364
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
X-ray / Number of thoracic vertebrae
|
HOM
|
5f:5m
|
|
|
NotProcessed |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Immunophenotyping / Eosinophils
|
HOM
|
3f:3m
|
|
|
NotProcessed |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Indirect Calorimetry / Body weight before experiment
|
HOM
|
f:8m
|
|
|
NotProcessed |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP2
|
HOM
|
7f:8m
|
|
|
NotProcessed |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Fear Conditioning / % Pre-cue freezing total
|
HOM
|
4f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.673
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Heart Weight / Heart weight normalised against body weight
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
X-ray / Radius
|
HOM
|
5f:5m
|
|
|
NotProcessed |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Eye Morphology / Corneal deposits
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Indirect Calorimetry / Total food intake
|
HOM
|
f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.787
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
X-ray / Fibula
|
HOM
|
5f:5m
|
|
|
NotProcessed |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Fear Conditioning / % Context freezing total
|
HOM
|
7f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.452
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Open Field / Percentage center time
|
HOM
|
7f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.541
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
X-ray / Shape of vertebrae
|
HOM
|
5f:5m
|
|
|
NotProcessed |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Auditory Brain Stem Response / 6kHz-evoked ABR Threshold
|
HOM
|
2f:2m
|
Reference Range Plus Test framework; quantile = 0.95 (Tails probability = 0.025)
|
0.0261
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Fear Conditioning / % Freezing duration cue-2
|
HOM
|
4f:8m
|
|
|
NotProcessed |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
X-ray / Brachydactyly
|
HOM
|
5f:5m
|
|
|
NotProcessed |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Body Composition (DEXA lean/fat) / Body length
|
HOM
|
7f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.440
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Vibrissae - presence
|
HOM
|
7f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Thyroid
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Thyroid
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Thyroid
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Thyroid
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Lower teeth appearance
|
HOM
|
7f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
X-ray / Scapulae
|
HOM
|
5f:5m
|
|
|
NotProcessed |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Shock Threshold / Shock Intensity Vocalization
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Eye Morphology / Lens Opacity
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Skin texture - back paws
|
HOM
|
7f:8m
|
|
|
NotProcessed |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Open Field / Number of Rears
|
HOM
|
28f:32m
|
|
|
NotProcessed |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Forelimbs - shape
|
HOM
|
7f:8m
|
|
|
NotProcessed |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Open Field / Periphery distance travelled
|
HOM
|
7f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.373
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Immunophenotyping / NKT cells (panel A)
|
HOM
|
3f:3m
|
|
|
NotProcessed |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Eye Morphology / Corneal mineralization
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
X-ray / Zygomatic bone
|
HOM
|
5f:5m
|
|
|
NotProcessed |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Heart Weight / Body weight
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Spleen
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Spleen
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Spleen
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Spleen
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Fear Conditioning / Freezing duration habituation
|
HOM
|
14f:16m
|
|
|
NotProcessed |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Clinical Chemistry / Calcium
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.109
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Immunophenotyping / B1B Cells
|
HOM
|
3f:3m
|
|
|
NotProcessed |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Echo / HR
|
HOM
|
7f:8m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.0783
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
X-ray / Shape of ribs
|
HOM
|
5f:5m
|
Fisher Exact Test framework
|
0.250
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Open Field / Percentage center movement time
|
HOM
|
7f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.520
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Tail elevation
|
HOM
|
7f:8m
|
|
|
NotProcessed |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Epididymis
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Epididymis
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Epididymis
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Epididymis
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Contact righting
|
HOM
|
7f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Skin color - ear
|
HOM
|
7f:8m
|
|
|
NotProcessed |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Electrocardiogram (ECG) / Number of signals
|
HOM
|
7f:8m
|
|
|
NotProcessed |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Hindlimb nail - number
|
HOM
|
7f:8m
|
|
|
NotProcessed |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Grip Strength / Forelimb and hindlimb grip strength normalised against body weight
|
HOM
|
7f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.891
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Esophagus
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Esophagus
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Esophagus
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Esophagus
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Immunophenotyping / DN NKT cells
|
HOM
|
3f:3m
|
|
|
NotProcessed |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Coat - hair texture / appearance - head
|
HOM
|
7f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Grip Strength / Body weight
|
HOM
|
7f:8m
|
|
|
NotProcessed |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Intraperitoneal glucose tolerance test (IPGTT) / Area under glucose response curve
|
HOM
|
7f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.00552
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Coat - color - abdomen
|
HOM
|
7f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP1_S
|
HOM
|
7f:8m
|
|
|
NotProcessed |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Eye Morphology / Pupil Dilation
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
0.297
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI3
|
HOM
|
7f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0160
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Body Composition (DEXA lean/fat) / Fat mass
|
HOM
|
7f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.402
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Fear Conditioning / % Freezing duration habituation-2
|
HOM
|
7f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.834
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Auditory Brain Stem Response / 30kHz-evoked ABR Threshold
|
HOM
|
2f:2m
|
Reference Range Plus Test framework; quantile = 0.95 (Tails probability = 0.025)
|
8.60×10-05
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Eye Morphology / Left inner nuclear layer
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.284
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Clinical Chemistry / Phosphorus
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.00685
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Hindpaw - shape
|
HOM
|
7f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Tremor
|
HOM
|
7f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Immunophenotyping / RP Macrophage (F4/80+)
|
HOM
|
3f:3m
|
|
|
NotProcessed |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Viability Primary Screen / Viability Outcome
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Genitalia - morphology
|
HOM
|
7f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Brain
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Brain
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Brain
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Brain
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Lymph node
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Lymph node
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Lymph node
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Lymph node
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Indirect Calorimetry / Total water intake
|
HOM
|
f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.0638
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Head morphology
|
HOM
|
7f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Electrocardiogram (ECG) / ST
|
HOM
|
7f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.985
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Indirect Calorimetry / Respiratory Exchange Ratio
|
HOM
|
f:5m
|
Linear Mixed Model framework, LME, not including Weight
|
0.401
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Upper teeth appearance
|
HOM
|
7f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Indirect Calorimetry / Carbon dioxide production
|
HOM
|
f:170m
|
|
|
NotProcessed |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Intraperitoneal glucose tolerance test (IPGTT) / Body Weight
|
HOM
|
7f:8m
|
|
|
NotProcessed |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Open Field / Center distance travelled
|
HOM
|
7f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.861
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Auditory Brain Stem Response / 18kHz-evoked ABR Threshold
|
HOM
|
2f:2m
|
Reference Range Plus Test framework; quantile = 0.95 (Tails probability = 0.025)
|
0.0261
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Eye Morphology / Corneal vascularization
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Eye Morphology / Retinal Blood Vessels Pattern
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Clinical Chemistry / Triglycerides
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.775
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Fear Conditioning / Freezing duration pre-cue
|
HOM
|
8f:16m
|
|
|
NotProcessed |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
X-ray / Clavicle
|
HOM
|
5f:5m
|
|
|
NotProcessed |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Eye Morphology / Right total retinal thickness
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.671
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Body Weight / Body weight curve
|
HOM
|
46f:66m
|
|
|
NotProcessed |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Fear Conditioning / % Freezing duration context-1
|
HOM
|
7f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0213
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Auditory Brain Stem Response / Body weight
|
HOM
|
2f:2m
|
|
|
NotProcessed |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Activity (body position)
|
HOM
|
7f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP1
|
HOM
|
7f:8m
|
|
|
NotProcessed |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Liver
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Liver
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Liver
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Liver
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Immunophenotyping / Monocytes
|
HOM
|
3f:3m
|
|
|
NotProcessed |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Hindlimb digit - size
|
HOM
|
7f:8m
|
|
|
NotProcessed |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Fear Conditioning / % Freezing duration habituation-1
|
HOM
|
7f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.732
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Indirect Calorimetry / Cumulative food intake
|
HOM
|
f:176m
|
|
|
NotProcessed |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
X-ray / Digit integrity
|
HOM
|
5f:5m
|
Fisher Exact Test framework
|
0.594
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Thymus
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Thymus
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Thymus
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Thymus
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Eye Morphology / Slit Lamp observation
|
HOM
|
2f:3m
|
|
|
NotProcessed |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Skin texture - snout
|
HOM
|
7f:8m
|
|
|
NotProcessed |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Clinical Chemistry / Total protein
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.433
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Eye Morphology / Pupil Position
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
0.317
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Hindlimbs - position
|
HOM
|
7f:8m
|
|
|
NotProcessed |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Body Composition (DEXA lean/fat) / Fat/Body weight
|
HOM
|
7f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.262
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Immunophenotyping / T Cells (panel B)
|
HOM
|
3f:3m
|
|
|
NotProcessed |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Immunophenotyping / Follicular B Cells
|
HOM
|
3f:3m
|
|
|
NotProcessed |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
X-ray / Number of cervical vertebrae
|
HOM
|
5f:5m
|
|
|
NotProcessed |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Open Field / Latency to center entry
|
HOM
|
7f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.422
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Eye Morphology / Eyelid closure
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Shock Threshold / Shock Intensity Jump
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Forelimbs - size
|
HOM
|
7f:8m
|
|
|
NotProcessed |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
X-ray / Fusion of vertebrae
|
HOM
|
5f:5m
|
|
|
NotProcessed |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Echo / LVIDd
|
HOM
|
7f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.641
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Mammary gland
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Mammary gland
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Mammary gland
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Mammary gland
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
X-ray / Tibia
|
HOM
|
5f:5m
|
|
|
NotProcessed |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Tail - morphology
|
HOM
|
7f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Coat - color pattern - abdomen
|
HOM
|
7f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Eye Morphology / Iris transilumination
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Hindlimb nail - length
|
HOM
|
7f:8m
|
|
|
NotProcessed |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Clinical Chemistry / Aspartate aminotransferase
|
HOM
|
7f:7m
|
Linear Model Using Generalized Least Squares framework, GLS, including Weight
|
0.369
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Vocalization
|
HOM
|
7f:8m
|
Fisher Exact Test framework
|
0.242
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Immunophenotyping / cDCs
|
HOM
|
3f:3m
|
|
|
NotProcessed |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Grip Strength / Forelimb and hindlimb grip strength measurement mean
|
HOM
|
7f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.683
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Indirect Calorimetry / Cumulative water intake
|
HOM
|
f:154m
|
|
|
NotProcessed |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Indirect Calorimetry / Heat production (metabolic rate)
|
HOM
|
f:170m
|
|
|
NotProcessed |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
X-ray / Syndactylism
|
HOM
|
5f:5m
|
|
|
NotProcessed |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Open Field / Whole arena resting time
|
HOM
|
7f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.440
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Teeth presence
|
HOM
|
7f:8m
|
|
|
NotProcessed |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Eye Morphology / Vitreous
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
0.0995
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Eye Morphology / Lens
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Head size
|
HOM
|
7f:8m
|
|
|
NotProcessed |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Grip Strength / Forelimb grip strength normalised against body weight
|
HOM
|
7f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.483
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Coat - color pattern - back
|
HOM
|
7f:8m
|
|
|
NotProcessed |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Eye Morphology / Optic Disc
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
8.84×10-05
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Open Field / Center average speed
|
HOM
|
7f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.166
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Challenge Whole Body Plethysmography / Enhanced pause (Penh)
|
HOM
|
288f:278m
|
|
|
NotProcessed |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Eye Morphology / Narrow eye opening
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Immunophenotyping / NK cells (panel A)
|
HOM
|
3f:3m
|
|
|
NotProcessed |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Immunophenotyping / B2B Cells
|
HOM
|
3f:3m
|
|
|
NotProcessed |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Heart Weight / Heart weight
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.0156
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Forepaw - shape
|
HOM
|
7f:8m
|
|
|
NotProcessed |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
X-ray / Alive
|
HOM
|
5f:5m
|
|
|
NotProcessed |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Body Composition (DEXA lean/fat) / Bone Mineral Content (excluding skull)
|
HOM
|
7f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.348
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Skin color - snout
|
HOM
|
7f:8m
|
|
|
NotProcessed |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Prostate
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Prostate
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Prostate
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Prostate
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Coat - hair texture / appearance - back
|
HOM
|
7f:8m
|
|
|
NotProcessed |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Skin
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Skin
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Skin
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Skin
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Immunophenotyping / Spleen weight
|
HOM
|
3f:3m
|
|
|
NotProcessed |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Immunophenotyping / Total number of acquired events in Panel B
|
HOM
|
3f:3m
|
|
|
NotProcessed |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Clinical Chemistry / HDL-cholesterol
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.105
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Lung
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Lung
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Lung
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Lung
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Eye Morphology / Persistence of hyaloid vascular system
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
0.361
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI2
|
HOM
|
7f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.189
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - S
|
HOM
|
7f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0381
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Eye Morphology / Pupil Shape
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
0.307
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Intraperitoneal glucose tolerance test (IPGTT) / Blood glucose concentration
|
HOM
|
35f:40m
|
|
|
NotProcessed |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Hot Plate / Type of response
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Open Field / Periphery average speed
|
HOM
|
7f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.00281
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Fear Conditioning / Freezing duration cue
|
HOM
|
8f:16m
|
|
|
NotProcessed |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
X-ray / Processes on vertebrae
|
HOM
|
5f:5m
|
|
|
NotProcessed |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Fertility of Homozygous Knock-out Mice / Gross Findings Male
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Eye Morphology / Eye
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Eye Morphology / Right vitreous humor thickness
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
2.18×10-06
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
X-ray / Maxilla/Pre-maxilla
|
HOM
|
5f:5m
|
|
|
NotProcessed |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Fear Conditioning / Context freezing total
|
HOM
|
7f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.450
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Transfer arousal
|
HOM
|
7f:8m
|
|
|
NotProcessed |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Eye Morphology / Right anterior chamber depth
|
HOM
|
5f:m
|
Linear Mixed Model framework, LME, not including Weight
|
0.114
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Pancreas
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Pancreas
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Pancreas
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Pancreas
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Mouth morphology
|
HOM
|
7f:8m
|
|
|
NotProcessed |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Immunophenotyping / Neutrophils
|
HOM
|
3f:3m
|
|
|
NotProcessed |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Head bobbing
|
HOM
|
7f:8m
|
|
|
NotProcessed |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Fear Conditioning / % Freezing duration context-2
|
HOM
|
7f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.519
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Heart Weight / Tibia length
|
HOM
|
5f:5m
|
Linear Mixed Model framework, LME, including Weight
|
0.00204
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Spinal cord
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Spinal cord
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Spinal cord
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Spinal cord
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Body Composition (DEXA lean/fat) / Lean/Body weight
|
HOM
|
7f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.210
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
X-ray / Number of ribs right
|
HOM
|
5f:5m
|
|
|
NotProcessed |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Skin texture - ear
|
HOM
|
7f:8m
|
|
|
NotProcessed |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Body Composition (DEXA lean/fat) / Body weight
|
HOM
|
7f:8m
|
|
|
NotProcessed |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Shock Threshold / Jump response
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Snout size
|
HOM
|
7f:8m
|
|
|
NotProcessed |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Open Field / Distance travelled - total
|
HOM
|
7f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.489
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Electrocardiogram (ECG) / PR
|
HOM
|
7f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.589
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Eye Morphology / Synechia
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Immunophenotyping / Total number of acquired events in Panel A
|
HOM
|
3f:3m
|
|
|
NotProcessed |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Auditory Brain Stem Response / 24kHz-evoked ABR Threshold
|
HOM
|
2f:2m
|
Reference Range Plus Test framework; quantile = 0.95 (Tails probability = 0.025)
|
7.80×10-05
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Clinical Chemistry / Total cholesterol
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.0722
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Genitalia - size
|
HOM
|
7f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Clinical Chemistry / Cholesterol ratio
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0140
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Open Field / Periphery permanence time
|
HOM
|
7f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.541
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Eye Morphology / Right inner nuclear layer
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.191
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Forelimb nail - length
|
HOM
|
7f:8m
|
|
|
NotProcessed |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Clinical Chemistry / Albumin
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.397
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Immunophenotyping / Others
|
HOM
|
3f:3m
|
|
|
NotProcessed |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Intraperitoneal glucose tolerance test (IPGTT) / Initial response to glucose challenge
|
HOM
|
7f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.000312
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Electrocardiogram (ECG) / HR
|
HOM
|
7f:8m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.445
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Echo / LVAWd
|
HOM
|
7f:8m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.161
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Aggression
|
HOM
|
7f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Open Field / Number of center entries
|
HOM
|
7f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.621
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
X-ray / Pelvis
|
HOM
|
5f:5m
|
|
|
NotProcessed |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Hindlimbs - shape
|
HOM
|
7f:8m
|
|
|
NotProcessed |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Grip Strength / Forelimb grip strength measurement mean
|
HOM
|
7f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.0729
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Adrenal gland
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Adrenal gland
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Adrenal gland
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Adrenal gland
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Startle response
|
HOM
|
7f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Immunophenotyping / Percentage of live gated events in Panel B
|
HOM
|
3f:3m
|
|
|
NotProcessed |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Rotarod / Latency to fall
|
HOM
|
21f:24m
|
|
|
NotProcessed |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - BN
|
HOM
|
7f:8m
|
|
|
NotProcessed |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Urinary bladder
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Urinary bladder
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Urinary bladder
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Urinary bladder
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Eye Morphology / Eyelid morphology
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Forelimb digit - shape
|
HOM
|
7f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Gall bladder
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Gall bladder
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Gall bladder
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Gall bladder
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Coat - color - back
|
HOM
|
7f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
X-ray / Femur
|
HOM
|
5f:5m
|
|
|
NotProcessed |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Challenge Whole Body Plethysmography / Tidal volume (TVb)
|
HOM
|
288f:278m
|
|
|
NotProcessed |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Eye Morphology / Cornea
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
0.753
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Open Field / Center permanence time
|
HOM
|
7f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.541
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Eye Morphology / Left anterior chamber depth
|
HOM
|
4f:m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.960
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Auditory Brain Stem Response / 12kHz-evoked ABR Threshold
|
HOM
|
2f:2m
|
Reference Range Plus Test framework; quantile = 0.95 (Tails probability = 0.025)
|
0.0410
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Grip Strength / Forelimb grip strength measurement
|
HOM
|
21f:24m
|
|
|
NotProcessed |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Open Field / Whole arena permanence
|
HOM
|
7f:8m
|
|
|
NotProcessed |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Hindpaw - size
|
HOM
|
7f:8m
|
|
|
NotProcessed |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Fear Conditioning / % Freezing duration pre-cue-2
|
HOM
|
4f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.259
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Rotarod / Body weight
|
HOM
|
7f:8m
|
|
|
NotProcessed |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Body Composition (DEXA lean/fat) / Bone Mineral Density (excluding skull)
|
HOM
|
7f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.246
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Upper lip morphology
|
HOM
|
7f:8m
|
|
|
NotProcessed |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Locomotor activity
|
HOM
|
7f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.00425
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Clinical Chemistry / LIH (Hemolysis Severity - available on AU analysers)
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Immunophenotyping / cDCs CD11b Type
|
HOM
|
3f:3m
|
|
|
NotProcessed |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Skeletal muscle
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Skeletal muscle
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Skeletal muscle
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Skeletal muscle
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Skin texture - tail
|
HOM
|
7f:8m
|
|
|
NotProcessed |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Indirect Calorimetry / Ambulatory activity (no. of beam cuts)
|
HOM
|
f:176m
|
|
|
NotProcessed |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Eye Morphology / Iris Pigmentation
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
0.277
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Vibrissae - appearance
|
HOM
|
7f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Immunophenotyping / MZB
|
HOM
|
3f:3m
|
|
|
NotProcessed |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Fear Conditioning / % Freezing duration cue-1
|
HOM
|
4f:8m
|
|
|
NotProcessed |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Hot Plate / Hot plate latency
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI1
|
HOM
|
7f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.600
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Eye Morphology / Retinal Blood Vessels
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP4
|
HOM
|
7f:8m
|
|
|
NotProcessed |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Eye Morphology / Lacrimation
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Fear Conditioning / Freezing duration context
|
HOM
|
21f:24m
|
|
|
NotProcessed |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
X-ray / Mandibles
|
HOM
|
5f:5m
|
|
|
NotProcessed |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Immunophenotyping / NKT Cells (panel B)
|
HOM
|
3f:3m
|
|
|
NotProcessed |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Seminal vesicle
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Seminal vesicle
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Seminal vesicle
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Seminal vesicle
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
X-ray / Humerus
|
HOM
|
5f:5m
|
|
|
NotProcessed |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Skin color - back paws
|
HOM
|
7f:8m
|
|
|
NotProcessed |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Large intestine
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Large intestine
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Large intestine
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Large intestine
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Limb grasp
|
HOM
|
7f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Skin color - whole body
|
HOM
|
7f:8m
|
|
|
NotProcessed |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Immunophenotyping / Percentage of live gated events in Panel A
|
HOM
|
3f:3m
|
|
|
NotProcessed |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
X-ray / Number of digits
|
HOM
|
5f:5m
|
|
|
NotProcessed |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Coat - hair distribution - abdomen
|
HOM
|
7f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Coat - color pattern - head
|
HOM
|
7f:8m
|
|
|
NotProcessed |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Clinical Chemistry / Urea (Blood Urea Nitrogen - BUN)
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0114
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Genitalia - presence
|
HOM
|
7f:8m
|
|
|
NotProcessed |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Open Field / Periphery resting time
|
HOM
|
7f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.302
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
X-ray / Number of lumbar vertebrae
|
HOM
|
5f:5m
|
|
|
NotProcessed |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Immunophenotyping / Transitional B Cells
|
HOM
|
3f:3m
|
|
|
NotProcessed |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Eye Morphology / Left outer nuclear layer
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.00982
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Hindlimb nail - shape
|
HOM
|
7f:8m
|
|
|
NotProcessed |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
X-ray / Ulna
|
HOM
|
5f:5m
|
|
|
NotProcessed |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Coat - hair distribution - head
|
HOM
|
7f:8m
|
Fisher Exact Test framework
|
0.00580
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Uterus
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Uterus
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Uterus
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Uterus
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Eye Morphology / Corneal Sclerization
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Hindlimb digit - number
|
HOM
|
7f:8m
|
|
|
NotProcessed |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Clinical Chemistry / Alkaline phosphatase
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.263
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Stomach
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Stomach
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Stomach
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Stomach
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Tail - length
|
HOM
|
7f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Indirect Calorimetry / Body weight after experiment
|
HOM
|
f:8m
|
|
|
NotProcessed |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Eye Morphology / Eye Hemorrhage or Blood Presence
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Open Field / Number of rears - total
|
HOM
|
7f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.867
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Unexpected behaviors
|
HOM
|
7f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
X-ray / Teeth
|
HOM
|
5f:5m
|
|
|
NotProcessed |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Fear Conditioning / % Freezing duration context-3
|
HOM
|
7f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.615
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - Global
|
HOM
|
7f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0881
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
X-ray / Number of ribs left
|
HOM
|
5f:5m
|
|
|
NotProcessed |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Open Field / Distance travelled
|
HOM
|
28f:32m
|
|
|
NotProcessed |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Hindlimbs - size
|
HOM
|
7f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Skin texture - front paws
|
HOM
|
7f:8m
|
|
|
NotProcessed |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Rotarod / Latency to fall mean
|
HOM
|
7f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.00812
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Body Composition (DEXA lean/fat) / Bone Area
|
HOM
|
7f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.277
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Immunophenotyping / NK Cells (panel B)
|
HOM
|
3f:3m
|
|
|
NotProcessed |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Body Weight / Body weight
|
HOM
|
7f:8m
|
|
|
NotProcessed |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Eye Morphology / Fusion between cornea and lens
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Coat - color - head
|
HOM
|
7f:8m
|
|
|
NotProcessed |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Electrocardiogram (ECG) / QT
|
HOM
|
7f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.858
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Echo / LVIDs
|
HOM
|
7f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.441
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Fear Conditioning / % Cue freezing total
|
HOM
|
4f:8m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.343
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Heart Weight / Heart weight normalised against tibia length
|
HOM
|
5f:5m
|
|
|
NotProcessed |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Eye Morphology / Right outer nuclear layer
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0709
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Hindlimb digit - shape
|
HOM
|
7f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Forepaw - size
|
HOM
|
7f:8m
|
|
|
NotProcessed |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Intraperitoneal glucose tolerance test (IPGTT) / Fasted blood glucose concentration
|
HOM
|
7f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.00144
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Heart
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Heart
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Heart
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Heart
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Clinical Chemistry / Total bilirubin
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0269
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Indirect Calorimetry / Total activity (no. of fine movement + no. of beam cuts)
|
HOM
|
f:176m
|
|
|
NotProcessed |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Forelimbs - position
|
HOM
|
7f:8m
|
|
|
NotProcessed |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
X-ray / Fusion of ribs
|
HOM
|
5f:5m
|
|
|
NotProcessed |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Shock Threshold / Shock Intensity Flinch
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP3_S
|
HOM
|
7f:8m
|
|
|
NotProcessed |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Body Composition (DEXA lean/fat) / BMC/Body weight
|
HOM
|
7f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.325
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Lower lip morphology
|
HOM
|
7f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Skin color - front paws
|
HOM
|
7f:8m
|
|
|
NotProcessed |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Trachea
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Trachea
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Trachea
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Trachea
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Testes
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Testes
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Testes
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Testes
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Coat - hair texture / appearance - abdomen
|
HOM
|
7f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Hot Plate / Body weight
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Open Field / Center resting time
|
HOM
|
7f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.439
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP2_S
|
HOM
|
7f:8m
|
|
|
NotProcessed |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Clinical Chemistry / Glucose
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
3.13×10-05
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Eye Morphology / Retinal Blood Vessels Structure
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Fertility of Homozygous Knock-out Mice / Gross Findings Female
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Eye Morphology / Left total retinal thickness
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.321
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
X-ray / Joints
|
HOM
|
5f:5m
|
|
|
NotProcessed |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Rotarod / Passive rotation
|
HOM
|
21f:24m
|
|
|
NotProcessed |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Fear Conditioning / Freezing duration post-us
|
HOM
|
7f:8m
|
|
|
NotProcessed |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Grip Strength / Forelimb and hindlimb grip strength measurement
|
HOM
|
21f:24m
|
|
|
NotProcessed |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Eye Morphology / Corneal ulcer
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
X-ray / Skull shape
|
HOM
|
5f:5m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Echo / Fractional Shortening
|
HOM
|
7f:8m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.0253
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Forelimb nail - number
|
HOM
|
7f:8m
|
|
|
NotProcessed |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Gait
|
HOM
|
7f:8m
|
|
|
NotProcessed |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Immunophenotyping / pDCs
|
HOM
|
3f:3m
|
|
|
NotProcessed |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Kidney
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Kidney
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Kidney
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Kidney
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Indirect Calorimetry / Oxygen consumption
|
HOM
|
f:170m
|
|
|
NotProcessed |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Electrocardiogram (ECG) / QRS
|
HOM
|
7f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.636
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Ears
|
HOM
|
7f:8m
|
|
|
NotProcessed |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Small intestine
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Small intestine
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Small intestine
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Forelimb digit - number
|
HOM
|
7f:8m
|
|
|
NotProcessed |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Tail - presence
|
HOM
|
7f:8m
|
|
|
NotProcessed |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI4
|
HOM
|
7f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0126
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
X-ray / Tibia length
|
HOM
|
5f:5m
|
Linear Mixed Model framework, LME, including Weight
|
0.00912
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Body Composition (DEXA lean/fat) / Lean mass
|
HOM
|
7f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.312
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP3
|
HOM
|
7f:8m
|
|
|
NotProcessed |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Eye Morphology / Pupil Light Response
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
0.287
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP4_S
|
HOM
|
7f:8m
|
|
|
NotProcessed |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Open Field / Whole arena average speed
|
HOM
|
7f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.00592
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Fear Conditioning / % Freezing duration pre-cue-1
|
HOM
|
4f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.669
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Eye Morphology / Corneal opacity
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
0.697
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
X-ray / Number of pelvic vertebrae
|
HOM
|
5f:5m
|
|
|
NotProcessed |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Ovary
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Ovary
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Ovary
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Ovary
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Immunophenotyping / B Cells
|
HOM
|
3f:3m
|
|
|
NotProcessed |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Challenge Whole Body Plethysmography / Frequency of breathing (f)
|
HOM
|
288f:278m
|
|
|
NotProcessed |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Skin color - tail
|
HOM
|
7f:8m
|
|
|
NotProcessed |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Eye with optic nerve
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Eye with optic nerve
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Eye with optic nerve
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Slc7a11tm1b(EUCOMM)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Eye with optic nerve
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |