All nervous system phenotype, behavior/neurological phenotype data for Parg

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Allele Center Procedure / Parameter Zygosity Mutants Statistical
Method
P Value Status Graph
Pargtm2b(KOMP)Mbp JAX Electroconvulsive Threshold Testing / mA threshold inducing clonic seizure HET 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.42157 Success
Pargtm2b(KOMP)Mbp JAX Combined SHIRPA and Dysmorphology / Activity (body position) HET 8f:8m Fisher Exact Test framework 1.0000 Success
Pargtm2b(KOMP)Mbp UC Davis Combined SHIRPA and Dysmorphology / Activity (body position) HET 8f:8m Fisher Exact Test framework 1.0000 Success
Pargtm2b(KOMP)Mbp JAX Combined SHIRPA and Dysmorphology / Head bobbing HET 8f:8m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Pargtm2b(KOMP)Mbp UC Davis Combined SHIRPA and Dysmorphology / Head bobbing HET 8f:8m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Pargtm2b(KOMP)Mbp JAX Light-Dark Test / Percent time in light HET 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.65528 Success
Pargtm2b(KOMP)Mbp JAX Combined SHIRPA and Dysmorphology / Trunk curl HET 8f:8m Fisher Exact Test framework 1.0000 Success
Pargtm2b(KOMP)Mbp UC Davis Combined SHIRPA and Dysmorphology / Trunk curl HET 8f:8m Fisher Exact Test framework 1.0000 Success
Pargtm2b(KOMP)Mbp UC Davis Gross Pathology and Tissue Collection / Uterus HET f:m Supplied as data Success
Pargtm2b(KOMP)Mbp TCP Gross Morphology Embryo E12.5 / Midbrain morphology HET f:m Supplied as data Success
Pargtm2b(KOMP)Mbp TCP Gross Morphology Embryo E12.5 / Midbrain morphology HET f:m Supplied as data Success
Pargtm2b(KOMP)Mbp JAX Light-Dark Test / Side changes HET 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.12841 Success
Pargtm2b(KOMP)Mbp JAX Hole-board Exploration / Total holepokes HET 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.14929 Success
Pargtm2b(KOMP)Mbp JAX Open Field / Distance travelled - total HET 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.58300 Success
Pargtm2b(KOMP)Mbp JAX Open Field / Number of rears - total HET 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.75921 Success
Pargtm2b(KOMP)Mbp JAX Combined SHIRPA and Dysmorphology / Unexpected behaviors HET 8f:8m Fisher Exact Test framework 1.0000 Success
Pargtm2b(KOMP)Mbp UC Davis Combined SHIRPA and Dysmorphology / Unexpected behaviors HET 8f:8m Fisher Exact Test framework 1.0000 Success
Pargtm2b(KOMP)Mbp JAX Light-Dark Test / Light side time spent HET 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.70112 Success
Pargtm2b(KOMP)Mbp JAX Open Field / Periphery permanence time HET 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.58679 Success
Pargtm2b(KOMP)Mbp TCP Gross Morphology Embryo E12.5 / Neural Tube Closure HET f:m Supplied as data Success
Pargtm2b(KOMP)Mbp TCP Gross Morphology Embryo E12.5 / Neural Tube Closure HET f:m Supplied as data Success
Pargtm2b(KOMP)Mbp TCP Gross Morphology Embryo E12.5 / Forebrain morphology HET f:m Supplied as data Success
Pargtm2b(KOMP)Mbp TCP Gross Morphology Embryo E12.5 / Forebrain morphology HET f:m Supplied as data Success
Pargtm2b(KOMP)Mbp JAX Open Field / Percentage center time HET 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.58588 Success
Pargtm2b(KOMP)Mbp JAX Combined SHIRPA and Dysmorphology / Aggression HET 8f:8m Fisher Exact Test framework 1.0000 Success
Pargtm2b(KOMP)Mbp UC Davis Combined SHIRPA and Dysmorphology / Aggression HET 8f:8m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Pargtm2b(KOMP)Mbp JAX Light-Dark Test / Time mobile light side HET 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.25600 Success
Pargtm2b(KOMP)Mbp UC Davis Grip Strength / Forelimb grip strength measurement mean HET 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.25238 Success
Pargtm2b(KOMP)Mbp JAX Grip Strength / Forelimb grip strength measurement mean HET 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.83981 Success
Pargtm2b(KOMP)Mbp JAX Combined SHIRPA and Dysmorphology / Startle response HET 8f:8m Fisher Exact Test framework 1.0000 Success
Pargtm2b(KOMP)Mbp UC Davis Combined SHIRPA and Dysmorphology / Startle response HET 8f:8m Fisher Exact Test framework 1.0000 Success
Pargtm2b(KOMP)Mbp JAX Gross Morphology Embryo E9.5 / Midbrain HET f:m Supplied as data Success
Pargtm2b(KOMP)Mbp TCP Gross Morphology Embryo E9.5 / Midbrain HET f:m Supplied as data Success
Pargtm2b(KOMP)Mbp TCP Gross Morphology Embryo E9.5 / Midbrain HET f:m Supplied as data Success
Pargtm2b(KOMP)Mbp JAX Gross Morphology Embryo E9.5 / Midbrain HET f:m Supplied as data Success
Pargtm2b(KOMP)Mbp TCP Gross Morphology Embryo E9.5 / Midbrain HOM f:m Supplied as data Success
Pargtm2b(KOMP)Mbp TCP Gross Morphology Embryo E9.5 / Midbrain HET f:m Supplied as data Success
Pargtm2b(KOMP)Mbp TCP Gross Morphology Embryo E12.5 / Hindbrain morphology HET f:m Supplied as data Success
Pargtm2b(KOMP)Mbp TCP Gross Morphology Embryo E12.5 / Hindbrain morphology HET f:m Supplied as data Success
Pargtm2b(KOMP)Mbp UC Davis Combined SHIRPA and Dysmorphology / Vocalization HET 8f:8m Fisher Exact Test framework 1.0000 Success
Pargtm2b(KOMP)Mbp JAX Combined SHIRPA and Dysmorphology / Vocalization HET 8f:8m Fisher Exact Test framework 1.0000 Success
Pargtm2b(KOMP)Mbp JAX Open Field / Periphery distance travelled HET 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.22779 Success
Pargtm2b(KOMP)Mbp JAX Light-Dark Test / Dark side time spent HET 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.70112 Success
Pargtm2b(KOMP)Mbp JAX Grip Strength / Forelimb and hindlimb grip strength measurement mean HET 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.084051 Success
Pargtm2b(KOMP)Mbp UC Davis Grip Strength / Forelimb and hindlimb grip strength measurement mean HET 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.77845 Success
Pargtm2b(KOMP)Mbp JAX Open Field / Center permanence time HET 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.58588 Success
Pargtm2b(KOMP)Mbp JAX Open Field / Whole arena resting time HET 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.59829 Success
Pargtm2b(KOMP)Mbp JAX Gross Morphology Embryo E9.5 / Neural tube closure HET f:m Supplied as data Success
Pargtm2b(KOMP)Mbp TCP Gross Morphology Embryo E9.5 / Neural tube closure HET f:m Supplied as data Success
Pargtm2b(KOMP)Mbp TCP Gross Morphology Embryo E9.5 / Neural tube closure HET f:m Supplied as data Success
Pargtm2b(KOMP)Mbp JAX Gross Morphology Embryo E9.5 / Neural tube closure HET f:m Supplied as data Success
Pargtm2b(KOMP)Mbp TCP Gross Morphology Embryo E9.5 / Neural tube closure HET f:m Supplied as data Success
Pargtm2b(KOMP)Mbp TCP Gross Morphology Embryo E9.5 / Neural tube closure HOM f:m Supplied as data Success
Pargtm2b(KOMP)Mbp JAX Grip Strength / Forelimb grip strength normalised against body weight HET 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.43458 Success
Pargtm2b(KOMP)Mbp UC Davis Grip Strength / Forelimb grip strength normalised against body weight HET 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.47709 Success
Pargtm2b(KOMP)Mbp JAX Combined SHIRPA and Dysmorphology / Locomotor activity HET 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.029799 Success
Pargtm2b(KOMP)Mbp UC Davis Combined SHIRPA and Dysmorphology / Locomotor activity HET 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.39655 Success
Pargtm2b(KOMP)Mbp JAX Eye Morphology / Optic Disc HET 8f:8m Fisher Exact Test framework 1.0000 Success
Pargtm2b(KOMP)Mbp UC Davis Eye Morphology / Optic Disc HET 8f:8m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Pargtm2b(KOMP)Mbp JAX Light-Dark Test / Time mobile dark side HET 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.18600 Success
Pargtm2b(KOMP)Mbp JAX Light-Dark Test / Fecal boli HET 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.70957 Success
Pargtm2b(KOMP)Mbp JAX Open Field / Center average speed HET 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.90912 Success
Pargtm2b(KOMP)Mbp JAX Combined SHIRPA and Dysmorphology / Contact righting HET 8f:8m Fisher Exact Test framework 1.0000 Success
Pargtm2b(KOMP)Mbp UC Davis Combined SHIRPA and Dysmorphology / Contact righting HET 8f:8m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Pargtm2b(KOMP)Mbp JAX Grip Strength / Forelimb and hindlimb grip strength normalised against body weight HET 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.26962 Success
Pargtm2b(KOMP)Mbp UC Davis Grip Strength / Forelimb and hindlimb grip strength normalised against body weight HET 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.44651 Success
Pargtm2b(KOMP)Mbp JAX Gross Morphology Embryo E9.5 / Forebrain HET f:m Supplied as data Success
Pargtm2b(KOMP)Mbp TCP Gross Morphology Embryo E9.5 / Forebrain HET f:m Supplied as data Success
Pargtm2b(KOMP)Mbp TCP Gross Morphology Embryo E9.5 / Forebrain HOM f:m Supplied as data Success
Pargtm2b(KOMP)Mbp JAX Gross Morphology Embryo E9.5 / Forebrain HET f:m Supplied as data Success
Pargtm2b(KOMP)Mbp TCP Gross Morphology Embryo E9.5 / Forebrain HET f:m Supplied as data Success
Pargtm2b(KOMP)Mbp TCP Gross Morphology Embryo E9.5 / Forebrain HET f:m Supplied as data Success
Pargtm2b(KOMP)Mbp JAX Combined SHIRPA and Dysmorphology / Gait HET 8f:8m Fisher Exact Test framework 1.0000 Success
Pargtm2b(KOMP)Mbp UC Davis Combined SHIRPA and Dysmorphology / Gait HET 8f:8m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Pargtm2b(KOMP)Mbp JAX Rotarod / Learning slope HET 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.082724 Success
Pargtm2b(KOMP)Mbp JAX Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI1 HET 4f:6m Mixed Model framework, generalized least squares, equation withoutWeight 0.36487 Success
Pargtm2b(KOMP)Mbp UC Davis Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI1 HET 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.93909 Success
Pargtm2b(KOMP)Mbp JAX Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI1 HET 4f:2m Not processed 1.0000 FAILED - Not enough data points in dependent variable 'IMPC_ACS_033_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Pargtm2b(KOMP)Mbp UC Davis Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI3 HET 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.020505 Success
Pargtm2b(KOMP)Mbp JAX Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI3 HET 4f:6m Mixed Model framework, generalized least squares, equation withoutWeight 0.52090 Success
Pargtm2b(KOMP)Mbp JAX Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI3 HET 4f:2m Not processed 1.0000 FAILED - Not enough data points in dependent variable 'IMPC_ACS_035_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Pargtm2b(KOMP)Mbp JAX Combined SHIRPA and Dysmorphology / Tremor HET 8f:8m Fisher Exact Test framework 1.0000 Success
Pargtm2b(KOMP)Mbp UC Davis Combined SHIRPA and Dysmorphology / Tremor HET 8f:8m Fisher Exact Test framework 1.0000 Success
Pargtm2b(KOMP)Mbp UC Davis Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI2 HET 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.026937 Success
Pargtm2b(KOMP)Mbp JAX Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI2 HET 4f:6m Mixed Model framework, generalized least squares, equation withoutWeight 0.50931 Success
Pargtm2b(KOMP)Mbp JAX Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI2 HET 4f:2m Not processed 1.0000 FAILED - Not enough data points in dependent variable 'IMPC_ACS_034_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Pargtm2b(KOMP)Mbp JAX Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - S HET 4f:6m Mixed Model framework, generalized least squares, equation withoutWeight 0.11400 Success
Pargtm2b(KOMP)Mbp UC Davis Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - S HET 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.69718 Success
Pargtm2b(KOMP)Mbp JAX Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - S HET 4f:2m Not processed 1.0000 FAILED - Not enough data points in dependent variable 'IMPC_ACS_006_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Pargtm2b(KOMP)Mbp JAX Light-Dark Test / Latency to first transition into dark HET 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.67318 Success
Pargtm2b(KOMP)Mbp JAX Rotarod / Learning difference HET 8f:8m Mixed Model framework, generalized least squares, equation withoutWeight 0.046812 Success
Pargtm2b(KOMP)Mbp JAX Open Field / Periphery average speed HET 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.34503 Success
Pargtm2b(KOMP)Mbp UC Davis Combined SHIRPA and Dysmorphology / Limb grasp HET 8f:8m Fisher Exact Test framework 0.63156 Success
Pargtm2b(KOMP)Mbp JAX Combined SHIRPA and Dysmorphology / Limb grasp HET 8f:8m Fisher Exact Test framework 1.0000 Success
Pargtm2b(KOMP)Mbp JAX Eye Morphology / Pupil Light Response HET 8f:8m Fisher Exact Test framework 1.0000 Success
Pargtm2b(KOMP)Mbp JAX Open Field / Whole arena average speed HET 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.58362 Success
Pargtm2b(KOMP)Mbp JAX Open Field / Center distance travelled HET 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.39691 Success
Pargtm2b(KOMP)Mbp JAX Light-Dark Test / Percent time in dark HET 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.65528 Success
Pargtm2b(KOMP)Mbp JAX Gross Morphology Embryo E9.5 / Neural tube morphology HET f:m Supplied as data Success
Pargtm2b(KOMP)Mbp JAX Gross Morphology Embryo E9.5 / Neural tube morphology HET f:m Supplied as data Success
Pargtm2b(KOMP)Mbp JAX Rotarod / Average duration HET 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.54900 Success
Pargtm2b(KOMP)Mbp TCP Gross Morphology Embryo E9.5 / Hindbrain HET f:m Supplied as data Success
Pargtm2b(KOMP)Mbp TCP Gross Morphology Embryo E9.5 / Hindbrain HOM f:m Supplied as data Success
Pargtm2b(KOMP)Mbp TCP Gross Morphology Embryo E9.5 / Hindbrain HET f:m Supplied as data Success
Pargtm2b(KOMP)Mbp TCP Gross Morphology Embryo E9.5 / Hindbrain HET f:m Supplied as data Success

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