Pstpip2em1(IMPC)Tcp
|
TCP
|
Fear Conditioning / Cue Baseline % Freezing Time
|
HOM
|
f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.0124
|
Successful |
Pstpip2em1(IMPC)Tcp
|
TCP
|
Open Field / Periphery resting time
|
HOM
|
4f:4m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0290
|
Successful |
Pstpip2em1(IMPC)Tcp
|
TCP
|
Open Field / Periphery resting time
|
HOM
|
4f:4m
|
Linear Mixed Model framework, LME, not including Weight
|
0.965
|
Successful |
Pstpip2em1(IMPC)Tcp
|
TCP
|
Open Field / Center permanence time series
|
HOM
|
16f:16m
|
|
|
NotProcessed |
Pstpip2em1(IMPC)Tcp
|
TCP
|
Open Field / Center permanence time series
|
HOM
|
16f:16m
|
|
|
NotProcessed |
Pstpip2em1(IMPC)Tcp
|
TCP
|
Combined SHIRPA and Dysmorphology / Activity (body position)
|
HOM
|
8f:8m
|
|
|
NotProcessed |
Pstpip2em1(IMPC)Tcp
|
TCP
|
Open Field / Whole arena average speed series
|
HOM
|
16f:16m
|
|
|
NotProcessed |
Pstpip2em1(IMPC)Tcp
|
TCP
|
Open Field / Whole arena average speed series
|
HOM
|
16f:16m
|
|
|
NotProcessed |
Pstpip2em1(IMPC)Tcp
|
TCP
|
Combined SHIRPA and Dysmorphology / Head bobbing
|
HOM
|
8f:8m
|
|
|
NotProcessed |
Pstpip2em1(IMPC)Tcp
|
TCP
|
Open Field / Center resting time series
|
HOM
|
16f:16m
|
|
|
NotProcessed |
Pstpip2em1(IMPC)Tcp
|
TCP
|
Open Field / Center resting time series
|
HOM
|
16f:16m
|
|
|
NotProcessed |
Pstpip2em1(IMPC)Tcp
|
TCP
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP1
|
HOM
|
8f:7m
|
|
|
NotProcessed |
Pstpip2em1(IMPC)Tcp
|
TCP
|
Combined SHIRPA and Dysmorphology / Trunk curl
|
HOM
|
8f:8m
|
|
|
NotProcessed |
Pstpip2em1(IMPC)Tcp
|
TCP
|
Fear Conditioning / Difference in Context and Conditioning Baseline % Freezing
|
HOM
|
f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.0879
|
Successful |
Pstpip2em1(IMPC)Tcp
|
TCP
|
Open Field / Periphery resting time series
|
HOM
|
16f:16m
|
|
|
NotProcessed |
Pstpip2em1(IMPC)Tcp
|
TCP
|
Open Field / Periphery resting time series
|
HOM
|
16f:16m
|
|
|
NotProcessed |
Pstpip2em1(IMPC)Tcp
|
TCP
|
Open Field / Distance travelled - total
|
HOM
|
4f:4m
|
Linear Mixed Model framework, LME, not including Weight
|
0.00345
|
Successful |
Pstpip2em1(IMPC)Tcp
|
TCP
|
Open Field / Distance travelled - total
|
HOM
|
4f:4m
|
Linear Mixed Model framework, LME, including Weight
|
0.965
|
Successful |
Pstpip2em1(IMPC)Tcp
|
TCP
|
Open Field / Center average speed series
|
HOM
|
16f:16m
|
|
|
NotProcessed |
Pstpip2em1(IMPC)Tcp
|
TCP
|
Open Field / Center average speed series
|
HOM
|
15f:16m
|
|
|
NotProcessed |
Pstpip2em1(IMPC)Tcp
|
TCP
|
Combined SHIRPA and Dysmorphology / Unexpected behaviors
|
HOM
|
8f:8m
|
|
|
NotProcessed |
Pstpip2em1(IMPC)Tcp
|
TCP
|
Open Field / Number of rears - total
|
HOM
|
4f:4m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0220
|
Successful |
Pstpip2em1(IMPC)Tcp
|
TCP
|
Open Field / Number of rears - total
|
HOM
|
4f:4m
|
Linear Model Using Generalized Least Squares framework, GLS, including Weight
|
0.948
|
Successful |
Pstpip2em1(IMPC)Tcp
|
TCP
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP2
|
HOM
|
8f:7m
|
|
|
NotProcessed |
Pstpip2em1(IMPC)Tcp
|
TCP
|
Open Field / Periphery distance travelled series
|
HOM
|
16f:16m
|
|
|
NotProcessed |
Pstpip2em1(IMPC)Tcp
|
TCP
|
Open Field / Periphery distance travelled series
|
HOM
|
16f:16m
|
|
|
NotProcessed |
Pstpip2em1(IMPC)Tcp
|
TCP
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - Global
|
HOM
|
8f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.422
|
Successful |
Pstpip2em1(IMPC)Tcp
|
TCP
|
Open Field / Periphery permanence time
|
HOM
|
4f:4m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0922
|
Successful |
Pstpip2em1(IMPC)Tcp
|
TCP
|
Open Field / Periphery permanence time
|
HOM
|
4f:4m
|
Linear Mixed Model framework, LME, not including Weight
|
0.753
|
Successful |
Pstpip2em1(IMPC)Tcp
|
TCP
|
Open Field / Distance travelled
|
HOM
|
16f:16m
|
|
|
NotProcessed |
Pstpip2em1(IMPC)Tcp
|
TCP
|
Open Field / Distance travelled
|
HOM
|
16f:16m
|
|
|
NotProcessed |
Pstpip2em1(IMPC)Tcp
|
TCP
|
Open Field / Latency to center entry
|
HOM
|
4f:4m
|
Linear Mixed Model framework, LME, not including Weight
|
0.224
|
Successful |
Pstpip2em1(IMPC)Tcp
|
TCP
|
Open Field / Latency to center entry
|
HOM
|
4f:4m
|
Linear Mixed Model framework, LME, not including Weight
|
0.405
|
Successful |
Pstpip2em1(IMPC)Tcp
|
TCP
|
Open Field / Percentage center time
|
HOM
|
4f:4m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0922
|
Successful |
Pstpip2em1(IMPC)Tcp
|
TCP
|
Open Field / Percentage center time
|
HOM
|
4f:4m
|
Linear Mixed Model framework, LME, not including Weight
|
0.753
|
Successful |
Pstpip2em1(IMPC)Tcp
|
TCP
|
Open Field / Number of center entries series
|
HOM
|
16f:16m
|
|
|
NotProcessed |
Pstpip2em1(IMPC)Tcp
|
TCP
|
Open Field / Number of center entries series
|
HOM
|
16f:16m
|
|
|
NotProcessed |
Pstpip2em1(IMPC)Tcp
|
TCP
|
Combined SHIRPA and Dysmorphology / Aggression
|
HOM
|
8f:8m
|
|
|
NotProcessed |
Pstpip2em1(IMPC)Tcp
|
TCP
|
Open Field / Number of center entries
|
HOM
|
4f:4m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0372
|
Successful |
Pstpip2em1(IMPC)Tcp
|
TCP
|
Open Field / Number of center entries
|
HOM
|
4f:4m
|
Linear Mixed Model framework, LME, including Weight
|
0.156
|
Successful |
Pstpip2em1(IMPC)Tcp
|
TCP
|
Combined SHIRPA and Dysmorphology / Startle response
|
HOM
|
8f:8m
|
|
|
NotProcessed |
Pstpip2em1(IMPC)Tcp
|
TCP
|
Grip Strength / Forelimb grip strength measurement mean
|
HOM
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.888
|
Successful |
Pstpip2em1(IMPC)Tcp
|
TCP
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - BN
|
HOM
|
8f:7m
|
|
|
NotProcessed |
Pstpip2em1(IMPC)Tcp
|
TCP
|
Indirect Calorimetry / Total activity (no. of fine movement + no. of beam cuts)
|
HOM
|
474f:409m
|
|
|
NotProcessed |
Pstpip2em1(IMPC)Tcp
|
TCP
|
Open Field / Number of Rears
|
HOM
|
16f:16m
|
|
|
NotProcessed |
Pstpip2em1(IMPC)Tcp
|
TCP
|
Open Field / Number of Rears
|
HOM
|
16f:16m
|
|
|
NotProcessed |
Pstpip2em1(IMPC)Tcp
|
TCP
|
Combined SHIRPA and Dysmorphology / Vocalization
|
HOM
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Pstpip2em1(IMPC)Tcp
|
TCP
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP3_S
|
HOM
|
8f:7m
|
|
|
NotProcessed |
Pstpip2em1(IMPC)Tcp
|
TCP
|
Open Field / Periphery distance travelled
|
HOM
|
4f:4m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0109
|
Successful |
Pstpip2em1(IMPC)Tcp
|
TCP
|
Open Field / Periphery distance travelled
|
HOM
|
4f:4m
|
Linear Mixed Model framework, LME, including Weight
|
0.827
|
Successful |
Pstpip2em1(IMPC)Tcp
|
TCP
|
Grip Strength / Forelimb and hindlimb grip strength measurement mean
|
HOM
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
2.70×10-05
|
Successful |
Pstpip2em1(IMPC)Tcp
|
TCP
|
Open Field / Center permanence time
|
HOM
|
4f:4m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0922
|
Successful |
Pstpip2em1(IMPC)Tcp
|
TCP
|
Open Field / Center permanence time
|
HOM
|
4f:4m
|
Linear Mixed Model framework, LME, not including Weight
|
0.753
|
Successful |
Pstpip2em1(IMPC)Tcp
|
TCP
|
Grip Strength / Forelimb grip strength measurement
|
HOM
|
24f:24m
|
|
|
NotProcessed |
Pstpip2em1(IMPC)Tcp
|
TCP
|
Open Field / Whole arena resting time
|
HOM
|
4f:4m
|
Linear Mixed Model framework, LME, including Weight
|
0.00758
|
Successful |
Pstpip2em1(IMPC)Tcp
|
TCP
|
Open Field / Whole arena resting time
|
HOM
|
4f:4m
|
Linear Mixed Model framework, LME, including Weight
|
0.684
|
Successful |
Pstpip2em1(IMPC)Tcp
|
TCP
|
Grip Strength / Forelimb grip strength normalised against body weight
|
HOM
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.431
|
Successful |
Pstpip2em1(IMPC)Tcp
|
TCP
|
Combined SHIRPA and Dysmorphology / Locomotor activity
|
HOM
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
6.57×10-06
|
Successful |
Pstpip2em1(IMPC)Tcp
|
TCP
|
Open Field / Percentage center movement time
|
HOM
|
4f:4m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0788
|
Successful |
Pstpip2em1(IMPC)Tcp
|
TCP
|
Open Field / Percentage center movement time
|
HOM
|
4f:4m
|
Linear Mixed Model framework, LME, not including Weight
|
0.721
|
Successful |
Pstpip2em1(IMPC)Tcp
|
TCP
|
Open Field / Center resting time
|
HOM
|
4f:4m
|
Linear Mixed Model framework, LME, not including Weight
|
0.245
|
Successful |
Pstpip2em1(IMPC)Tcp
|
TCP
|
Open Field / Center resting time
|
HOM
|
4f:4m
|
Linear Mixed Model framework, LME, including Weight
|
0.393
|
Successful |
Pstpip2em1(IMPC)Tcp
|
TCP
|
Eye Morphology / Optic Disc
|
HOM
|
8f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Pstpip2em1(IMPC)Tcp
|
TCP
|
Combined SHIRPA and Dysmorphology / Tail elevation
|
HOM
|
8f:8m
|
|
|
NotProcessed |
Pstpip2em1(IMPC)Tcp
|
TCP
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP2_S
|
HOM
|
8f:7m
|
|
|
NotProcessed |
Pstpip2em1(IMPC)Tcp
|
TCP
|
Fear Conditioning / Conditioning Baseline % Freezing Time
|
HOM
|
f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.0368
|
Successful |
Pstpip2em1(IMPC)Tcp
|
TCP
|
Open Field / Periphery permanence time series
|
HOM
|
16f:16m
|
|
|
NotProcessed |
Pstpip2em1(IMPC)Tcp
|
TCP
|
Open Field / Periphery permanence time series
|
HOM
|
16f:16m
|
|
|
NotProcessed |
Pstpip2em1(IMPC)Tcp
|
TCP
|
Open Field / Center average speed
|
HOM
|
4f:4m
|
Linear Mixed Model framework, LME, not including Weight
|
0.233
|
Successful |
Pstpip2em1(IMPC)Tcp
|
TCP
|
Open Field / Center average speed
|
HOM
|
4f:4m
|
Linear Model Using Generalized Least Squares framework, GLS, including Weight
|
0.951
|
Successful |
Pstpip2em1(IMPC)Tcp
|
TCP
|
Combined SHIRPA and Dysmorphology / Contact righting
|
HOM
|
8f:8m
|
|
|
NotProcessed |
Pstpip2em1(IMPC)Tcp
|
TCP
|
Grip Strength / Forelimb and hindlimb grip strength normalised against body weight
|
HOM
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.000165
|
Successful |
Pstpip2em1(IMPC)Tcp
|
TCP
|
Grip Strength / Forelimb and hindlimb grip strength measurement
|
HOM
|
24f:24m
|
|
|
NotProcessed |
Pstpip2em1(IMPC)Tcp
|
TCP
|
Indirect Calorimetry / Ambulatory activity (no. of beam cuts)
|
HOM
|
474f:409m
|
|
|
NotProcessed |
Pstpip2em1(IMPC)Tcp
|
TCP
|
Combined SHIRPA and Dysmorphology / Gait
|
HOM
|
8f:8m
|
|
|
NotProcessed |
Pstpip2em1(IMPC)Tcp
|
TCP
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP1_S
|
HOM
|
8f:7m
|
|
|
NotProcessed |
Pstpip2em1(IMPC)Tcp
|
TCP
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI1
|
HOM
|
8f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.313
|
Successful |
Pstpip2em1(IMPC)Tcp
|
TCP
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP4
|
HOM
|
8f:7m
|
|
|
NotProcessed |
Pstpip2em1(IMPC)Tcp
|
TCP
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI3
|
HOM
|
8f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.997
|
Successful |
Pstpip2em1(IMPC)Tcp
|
TCP
|
Open Field / Periphery average speed series
|
HOM
|
16f:16m
|
|
|
NotProcessed |
Pstpip2em1(IMPC)Tcp
|
TCP
|
Open Field / Periphery average speed series
|
HOM
|
16f:16m
|
|
|
NotProcessed |
Pstpip2em1(IMPC)Tcp
|
TCP
|
Fear Conditioning / Difference in Cue Tone and Cue Baseline % Freezing
|
HOM
|
f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.423
|
Successful |
Pstpip2em1(IMPC)Tcp
|
TCP
|
Combined SHIRPA and Dysmorphology / Tremor
|
HOM
|
8f:8m
|
|
|
NotProcessed |
Pstpip2em1(IMPC)Tcp
|
TCP
|
Fear Conditioning / Difference in Conditioning Post-shock and Conditioning Baseline % Freezing
|
HOM
|
f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.190
|
Successful |
Pstpip2em1(IMPC)Tcp
|
TCP
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI2
|
HOM
|
8f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.478
|
Successful |
Pstpip2em1(IMPC)Tcp
|
TCP
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - S
|
HOM
|
8f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.538
|
Successful |
Pstpip2em1(IMPC)Tcp
|
TCP
|
Open Field / Periphery average speed
|
HOM
|
4f:4m
|
Linear Mixed Model framework, LME, including Weight
|
0.00286
|
Successful |
Pstpip2em1(IMPC)Tcp
|
TCP
|
Open Field / Periphery average speed
|
HOM
|
4f:4m
|
Linear Mixed Model framework, LME, including Weight
|
0.142
|
Successful |
Pstpip2em1(IMPC)Tcp
|
TCP
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI4
|
HOM
|
8f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.722
|
Successful |
Pstpip2em1(IMPC)Tcp
|
TCP
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP3
|
HOM
|
8f:7m
|
|
|
NotProcessed |
Pstpip2em1(IMPC)Tcp
|
TCP
|
Combined SHIRPA and Dysmorphology / Limb grasp
|
HOM
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Pstpip2em1(IMPC)Tcp
|
TCP
|
Eye Morphology / Pupil Light Response
|
HOM
|
8f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Pstpip2em1(IMPC)Tcp
|
TCP
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP4_S
|
HOM
|
8f:7m
|
|
|
NotProcessed |
Pstpip2em1(IMPC)Tcp
|
TCP
|
Open Field / Whole arena average speed
|
HOM
|
4f:4m
|
Linear Mixed Model framework, LME, including Weight
|
0.00698
|
Successful |
Pstpip2em1(IMPC)Tcp
|
TCP
|
Open Field / Whole arena average speed
|
HOM
|
4f:4m
|
Linear Model Using Generalized Least Squares framework, GLS, including Weight
|
0.906
|
Successful |
Pstpip2em1(IMPC)Tcp
|
TCP
|
Combined SHIRPA and Dysmorphology / Transfer arousal
|
HOM
|
8f:8m
|
|
|
NotProcessed |
Pstpip2em1(IMPC)Tcp
|
TCP
|
Open Field / Center distance travelled
|
HOM
|
4f:4m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0204
|
Successful |
Pstpip2em1(IMPC)Tcp
|
TCP
|
Open Field / Center distance travelled
|
HOM
|
4f:4m
|
Linear Model Using Generalized Least Squares framework, GLS, including Weight
|
0.342
|
Successful |
Pstpip2em1(IMPC)Tcp
|
TCP
|
Open Field / Center distance travelled series
|
HOM
|
16f:16m
|
|
|
NotProcessed |
Pstpip2em1(IMPC)Tcp
|
TCP
|
Open Field / Center distance travelled series
|
HOM
|
16f:16m
|
|
|
NotProcessed |
Pstpip2em1(IMPC)Tcp
|
TCP
|
Open Field / Whole arena resting time series
|
HOM
|
16f:16m
|
|
|
NotProcessed |
Pstpip2em1(IMPC)Tcp
|
TCP
|
Open Field / Whole arena resting time series
|
HOM
|
16f:16m
|
|
|
NotProcessed |