Knstrntm1b(KOMP)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Forelimb digit - size
|
HOM
|
12f:8m
|
|
|
NotProcessed |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Tail - thickness
|
HOM
|
12f:8m
|
|
|
NotProcessed |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Clinical Chemistry / Alanine aminotransferase
|
HOM
|
11f:6m
|
Linear Mixed Model framework, LME, not including Weight
|
0.737
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Eye Morphology / Ophthalmoscope Observation
|
HOM
|
2f:3m
|
|
|
NotProcessed |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Coat - hair distribution - back
|
HOM
|
12f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Eye Morphology / Bulging eye
|
HOM
|
12f:8m
|
Fisher Exact Test framework
|
0.00915
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Echo / LVPWd
|
HOM
|
5f:2m
|
Linear Mixed Model framework, LME, not including Weight
|
0.307
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Echo / LVPWd
|
HOM
|
7f:6m
|
Linear Mixed Model framework, LME, not including Weight
|
0.560
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Forelimb nail - shape
|
HOM
|
12f:8m
|
|
|
NotProcessed |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Electrocardiogram (ECG) / RR
|
HOM
|
7f:6m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.282
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Electrocardiogram (ECG) / RR
|
HOM
|
5f:2m
|
Linear Mixed Model framework, LME, not including Weight
|
0.743
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Skin texture - whole body
|
HOM
|
12f:8m
|
|
|
NotProcessed |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Eye Morphology / Left vitreous humour thickness
|
HOM
|
11f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.812
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Trunk curl
|
HOM
|
12f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Clinical Chemistry / Creatinine
|
HOM
|
11f:6m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0718
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Brain
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Brain
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Brain
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Brain
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Eye Morphology / Iris/Pupil
|
HOM
|
5f:2m
|
Fisher Exact Test framework
|
0.177
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
X-ray / Number of thoracic vertebrae
|
HOM
|
10f:7m
|
|
|
NotProcessed |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Hematology / Mean cell hemoglobin concentration
|
HOM
|
9f:6m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0476
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP2
|
HOM
|
12f:8m
|
|
|
NotProcessed |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Indirect Calorimetry / Body weight before experiment
|
HOM
|
9f:8m
|
|
|
NotProcessed |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Fear Conditioning / % Pre-cue freezing total
|
HOM
|
12f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0987
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Heart Weight / Heart weight normalised against body weight
|
HOM
|
11f:6m
|
|
|
NotProcessed |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
X-ray / Radius
|
HOM
|
10f:7m
|
|
|
NotProcessed |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Eye Morphology / Corneal deposits
|
HOM
|
5f:2m
|
Fisher Exact Test framework
|
0.00109
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Indirect Calorimetry / Total food intake
|
HOM
|
9f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.297
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
X-ray / Fibula
|
HOM
|
10f:7m
|
|
|
NotProcessed |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Fear Conditioning / % Context freezing total
|
HOM
|
12f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.913
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Open Field / Percentage center time
|
HOM
|
12f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.395
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Hematology / Eosinophil differential count
|
HOM
|
4f:2m
|
Linear Mixed Model framework, LME, not including Weight
|
0.401
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
X-ray / Shape of vertebrae
|
HOM
|
10f:7m
|
|
|
NotProcessed |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Auditory Brain Stem Response / 6kHz-evoked ABR Threshold
|
HOM
|
8f:5m
|
Reference Range Plus Test framework; quantile = 0.95 (Tails probability = 0.025)
|
0.0336
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Fear Conditioning / % Freezing duration cue-2
|
HOM
|
12f:8m
|
|
|
NotProcessed |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
X-ray / Brachydactyly
|
HOM
|
10f:7m
|
|
|
NotProcessed |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Body Composition (DEXA lean/fat) / Body length
|
HOM
|
5f:2m
|
Linear Mixed Model framework, LME, including Weight
|
0.448
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Body Composition (DEXA lean/fat) / Body length
|
HOM
|
7f:6m
|
Linear Mixed Model framework, LME, including Weight
|
0.915
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Thyroid
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Thyroid
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Thyroid
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Thyroid
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Vibrissae - presence
|
HOM
|
12f:8m
|
Fisher Exact Test framework
|
0.630
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Lower teeth appearance
|
HOM
|
12f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
X-ray / Scapulae
|
HOM
|
10f:7m
|
|
|
NotProcessed |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Shock Threshold / Shock Intensity Vocalization
|
HOM
|
12f:8m
|
|
|
NotProcessed |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Eye Morphology / Lens Opacity
|
HOM
|
5f:2m
|
Fisher Exact Test framework
|
0.0476
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Open Field / Number of Rears
|
HOM
|
48f:32m
|
|
|
NotProcessed |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Skin texture - back paws
|
HOM
|
12f:8m
|
|
|
NotProcessed |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Forelimbs - shape
|
HOM
|
12f:8m
|
|
|
NotProcessed |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Open Field / Periphery distance travelled
|
HOM
|
12f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.250
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Eye Morphology / Corneal mineralization
|
HOM
|
5f:2m
|
Fisher Exact Test framework
|
0.00125
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
X-ray / Zygomatic bone
|
HOM
|
10f:7m
|
|
|
NotProcessed |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Heart Weight / Body weight
|
HOM
|
11f:6m
|
|
|
NotProcessed |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Fear Conditioning / Freezing duration habituation
|
HOM
|
24f:16m
|
|
|
NotProcessed |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Clinical Chemistry / Calcium
|
HOM
|
11f:6m
|
Linear Mixed Model framework, LME, not including Weight
|
0.887
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Echo / HR
|
HOM
|
7f:6m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.640
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Echo / HR
|
HOM
|
5f:2m
|
Linear Mixed Model framework, LME, not including Weight
|
0.814
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
X-ray / Shape of ribs
|
HOM
|
10f:7m
|
Fisher Exact Test framework
|
0.393
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Open Field / Percentage center movement time
|
HOM
|
12f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.505
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Tail elevation
|
HOM
|
12f:8m
|
|
|
NotProcessed |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Spleen
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Spleen
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Spleen
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Spleen
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Epididymis
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Epididymis
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Epididymis
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Epididymis
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Contact righting
|
HOM
|
12f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Skin color - ear
|
HOM
|
12f:8m
|
|
|
NotProcessed |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Hindlimb nail - number
|
HOM
|
12f:8m
|
|
|
NotProcessed |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Electrocardiogram (ECG) / Number of signals
|
HOM
|
5f:2m
|
|
|
NotProcessed |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Electrocardiogram (ECG) / Number of signals
|
HOM
|
7f:6m
|
|
|
NotProcessed |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Hematology / Hematocrit
|
HOM
|
9f:6m
|
Linear Mixed Model framework, LME, not including Weight
|
1.16×10-05
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Grip Strength / Forelimb and hindlimb grip strength normalised against body weight
|
HOM
|
12f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0131
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Esophagus
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Esophagus
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Esophagus
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Esophagus
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Coat - hair texture / appearance - head
|
HOM
|
12f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Grip Strength / Body weight
|
HOM
|
12f:8m
|
|
|
NotProcessed |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Intraperitoneal glucose tolerance test (IPGTT) / Area under glucose response curve
|
HOM
|
12f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.666
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Coat - color - abdomen
|
HOM
|
12f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP1_S
|
HOM
|
12f:8m
|
|
|
NotProcessed |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Eye Morphology / Pupil Dilation
|
HOM
|
5f:2m
|
Fisher Exact Test framework
|
0.141
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Body Composition (DEXA lean/fat) / Fat mass
|
HOM
|
7f:3m
|
Linear Mixed Model framework, LME, including Weight
|
0.00659
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Body Composition (DEXA lean/fat) / Fat mass
|
HOM
|
5f:2m
|
Linear Mixed Model framework, LME, including Weight
|
0.149
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Fear Conditioning / % Freezing duration habituation-2
|
HOM
|
12f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0501
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI3
|
HOM
|
12f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.474
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Auditory Brain Stem Response / 30kHz-evoked ABR Threshold
|
HOM
|
8f:5m
|
Reference Range Plus Test framework; quantile = 0.95 (Tails probability = 0.025)
|
0.0261
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Eye Morphology / Left inner nuclear layer
|
HOM
|
11f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.00746
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Clinical Chemistry / Phosphorus
|
HOM
|
11f:6m
|
Linear Mixed Model framework, LME, not including Weight
|
0.906
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Hindpaw - shape
|
HOM
|
12f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Tremor
|
HOM
|
12f:8m
|
Fisher Exact Test framework
|
9.47×10-06
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Viability Primary Screen / Viability Outcome
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Genitalia - morphology
|
HOM
|
12f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Hematology / Large Unstained Cell (LUC) count
|
HOM
|
4f:2m
|
Linear Mixed Model framework, LME, not including Weight
|
0.659
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Lymph node
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Lymph node
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Lymph node
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Lymph node
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Indirect Calorimetry / Total water intake
|
HOM
|
9f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.00380
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Hematology / Lymphocyte cell count
|
HOM
|
4f:2m
|
Linear Mixed Model framework, LME, not including Weight
|
0.404
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Head morphology
|
HOM
|
12f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Electrocardiogram (ECG) / ST
|
HOM
|
5f:2m
|
Linear Mixed Model framework, LME, not including Weight
|
0.268
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Electrocardiogram (ECG) / ST
|
HOM
|
7f:6m
|
Linear Mixed Model framework, LME, not including Weight
|
0.708
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Indirect Calorimetry / Respiratory Exchange Ratio
|
HOM
|
3f:2m
|
|
|
NotProcessed |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Upper teeth appearance
|
HOM
|
12f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Indirect Calorimetry / Carbon dioxide production
|
HOM
|
66f:44m
|
|
|
NotProcessed |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Intraperitoneal glucose tolerance test (IPGTT) / Body Weight
|
HOM
|
12f:8m
|
|
|
NotProcessed |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Open Field / Center distance travelled
|
HOM
|
12f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.699
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Auditory Brain Stem Response / 18kHz-evoked ABR Threshold
|
HOM
|
8f:5m
|
Reference Range Plus Test framework; quantile = 0.95 (Tails probability = 0.025)
|
0.00658
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Eye Morphology / Corneal vascularization
|
HOM
|
5f:2m
|
Fisher Exact Test framework
|
0.00111
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Eye Morphology / Retinal Blood Vessels Pattern
|
HOM
|
12f:8m
|
Fisher Exact Test framework
|
0.240
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Clinical Chemistry / Triglycerides
|
HOM
|
11f:6m
|
Linear Mixed Model framework, LME, not including Weight
|
0.308
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Fear Conditioning / Freezing duration pre-cue
|
HOM
|
24f:16m
|
|
|
NotProcessed |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
X-ray / Clavicle
|
HOM
|
10f:7m
|
|
|
NotProcessed |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Eye Morphology / Right total retinal thickness
|
HOM
|
11f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.781
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Body Weight / Body weight curve
|
HOM
|
86f:57m
|
|
|
NotProcessed |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Fear Conditioning / % Freezing duration context-1
|
HOM
|
12f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.817
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Auditory Brain Stem Response / Body weight
|
HOM
|
8f:5m
|
|
|
NotProcessed |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Hematology / Platelet count
|
HOM
|
9f:6m
|
Linear Mixed Model framework, LME, not including Weight
|
2.57×10-12
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Activity (body position)
|
HOM
|
12f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP1
|
HOM
|
12f:8m
|
|
|
NotProcessed |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Liver
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Liver
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Liver
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Liver
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Hindlimb digit - size
|
HOM
|
12f:8m
|
|
|
NotProcessed |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Fear Conditioning / % Freezing duration habituation-1
|
HOM
|
12f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.414
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Indirect Calorimetry / Cumulative food intake
|
HOM
|
198f:176m
|
|
|
NotProcessed |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
X-ray / Digit integrity
|
HOM
|
10f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Thymus
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Thymus
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Thymus
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Thymus
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Eye Morphology / Slit Lamp observation
|
HOM
|
9f:6m
|
|
|
NotProcessed |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Skin texture - snout
|
HOM
|
12f:8m
|
|
|
NotProcessed |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Clinical Chemistry / Total protein
|
HOM
|
11f:6m
|
Linear Mixed Model framework, LME, not including Weight
|
0.832
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Eye Morphology / Pupil Position
|
HOM
|
5f:2m
|
Fisher Exact Test framework
|
0.151
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Hindlimbs - position
|
HOM
|
12f:8m
|
|
|
NotProcessed |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Body Composition (DEXA lean/fat) / Fat/Body weight
|
HOM
|
7f:3m
|
Linear Mixed Model framework, LME, not including Weight
|
0.00653
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Body Composition (DEXA lean/fat) / Fat/Body weight
|
HOM
|
5f:2m
|
Linear Mixed Model framework, LME, not including Weight
|
0.258
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
X-ray / Number of cervical vertebrae
|
HOM
|
10f:7m
|
|
|
NotProcessed |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Open Field / Latency to center entry
|
HOM
|
12f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.501
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Eye Morphology / Eyelid closure
|
HOM
|
12f:8m
|
Fisher Exact Test framework
|
0.00693
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Shock Threshold / Shock Intensity Jump
|
HOM
|
12f:8m
|
|
|
NotProcessed |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Forelimbs - size
|
HOM
|
12f:8m
|
|
|
NotProcessed |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
X-ray / Fusion of vertebrae
|
HOM
|
10f:7m
|
|
|
NotProcessed |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Echo / LVIDd
|
HOM
|
5f:2m
|
Linear Mixed Model framework, LME, not including Weight
|
0.579
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Echo / LVIDd
|
HOM
|
7f:6m
|
Linear Mixed Model framework, LME, not including Weight
|
0.750
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Mammary gland
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Mammary gland
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Mammary gland
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Mammary gland
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
X-ray / Tibia
|
HOM
|
10f:7m
|
|
|
NotProcessed |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Tail - morphology
|
HOM
|
12f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Coat - color pattern - abdomen
|
HOM
|
12f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Eye Morphology / Iris transilumination
|
HOM
|
5f:2m
|
Fisher Exact Test framework
|
0.0405
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Hindlimb nail - length
|
HOM
|
12f:8m
|
|
|
NotProcessed |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Clinical Chemistry / Aspartate aminotransferase
|
HOM
|
11f:6m
|
Linear Mixed Model framework, LME, not including Weight
|
0.176
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Hematology / Eosinophil cell count
|
HOM
|
4f:2m
|
Linear Mixed Model framework, LME, including Weight
|
0.376
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Vocalization
|
HOM
|
12f:8m
|
Fisher Exact Test framework
|
0.721
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Grip Strength / Forelimb and hindlimb grip strength measurement mean
|
HOM
|
12f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.115
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Hematology / Hemoglobin
|
HOM
|
9f:6m
|
Linear Mixed Model framework, LME, not including Weight
|
0.605
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Indirect Calorimetry / Cumulative water intake
|
HOM
|
198f:176m
|
|
|
NotProcessed |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
X-ray / Syndactylism
|
HOM
|
10f:7m
|
|
|
NotProcessed |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Indirect Calorimetry / Heat production (metabolic rate)
|
HOM
|
66f:44m
|
|
|
NotProcessed |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Open Field / Whole arena resting time
|
HOM
|
12f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.577
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Teeth presence
|
HOM
|
12f:8m
|
|
|
NotProcessed |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Eye Morphology / Vitreous
|
HOM
|
12f:8m
|
Fisher Exact Test framework
|
0.203
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Eye Morphology / Lens
|
HOM
|
5f:2m
|
Fisher Exact Test framework
|
0.0536
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Head size
|
HOM
|
12f:8m
|
|
|
NotProcessed |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Grip Strength / Forelimb grip strength normalised against body weight
|
HOM
|
12f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.459
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Eye Morphology / Left corneal thickness
|
HOM
|
8f:6m
|
Linear Mixed Model framework, LME, not including Weight
|
0.879
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Coat - color pattern - back
|
HOM
|
12f:8m
|
|
|
NotProcessed |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Eye Morphology / Optic Disc
|
HOM
|
12f:8m
|
Fisher Exact Test framework
|
0.266
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Open Field / Center average speed
|
HOM
|
12f:8m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.172
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Challenge Whole Body Plethysmography / Enhanced pause (Penh)
|
HOM
|
429f:429m
|
|
|
NotProcessed |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Eye Morphology / Narrow eye opening
|
HOM
|
12f:8m
|
Fisher Exact Test framework
|
0.00502
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Heart Weight / Heart weight
|
HOM
|
11f:6m
|
Linear Mixed Model framework, LME, including Weight
|
0.795
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Forepaw - shape
|
HOM
|
12f:8m
|
|
|
NotProcessed |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
X-ray / Alive
|
HOM
|
10f:7m
|
|
|
NotProcessed |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Body Composition (DEXA lean/fat) / Bone Mineral Content (excluding skull)
|
HOM
|
7f:3m
|
Linear Mixed Model framework, LME, including Weight
|
0.0434
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Body Composition (DEXA lean/fat) / Bone Mineral Content (excluding skull)
|
HOM
|
5f:2m
|
Linear Mixed Model framework, LME, including Weight
|
0.430
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Hematology / Neutrophil differential count
|
HOM
|
4f:2m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0940
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Skin color - snout
|
HOM
|
12f:8m
|
|
|
NotProcessed |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Prostate
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Prostate
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Prostate
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Prostate
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Coat - hair texture / appearance - back
|
HOM
|
12f:8m
|
|
|
NotProcessed |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Lung
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Lung
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Lung
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Lung
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Skin
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Skin
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Skin
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Clinical Chemistry / HDL-cholesterol
|
HOM
|
11f:6m
|
Linear Mixed Model framework, LME, not including Weight
|
0.752
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Eye Morphology / Persistence of hyaloid vascular system
|
HOM
|
12f:8m
|
Fisher Exact Test framework
|
0.278
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI2
|
HOM
|
12f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.556
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Eye Morphology / Pupil Shape
|
HOM
|
5f:2m
|
Fisher Exact Test framework
|
0.146
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - S
|
HOM
|
12f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.224
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Intraperitoneal glucose tolerance test (IPGTT) / Blood glucose concentration
|
HOM
|
60f:40m
|
|
|
NotProcessed |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Hot Plate / Type of response
|
HOM
|
12f:8m
|
|
|
NotProcessed |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Open Field / Periphery average speed
|
HOM
|
12f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.118
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
X-ray / Processes on vertebrae
|
HOM
|
10f:7m
|
|
|
NotProcessed |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Fear Conditioning / Freezing duration cue
|
HOM
|
24f:16m
|
|
|
NotProcessed |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Eye Morphology / Eye
|
HOM
|
12f:8m
|
Fisher Exact Test framework
|
0.00888
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Fertility of Homozygous Knock-out Mice / Gross Findings Male
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Eye Morphology / Right vitreous humor thickness
|
HOM
|
11f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.159
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
X-ray / Maxilla/Pre-maxilla
|
HOM
|
10f:7m
|
|
|
NotProcessed |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Fear Conditioning / Context freezing total
|
HOM
|
12f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.900
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Transfer arousal
|
HOM
|
12f:8m
|
|
|
NotProcessed |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Hematology / Lymphocyte differential count
|
HOM
|
4f:2m
|
Linear Mixed Model framework, LME, not including Weight
|
0.913
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Pancreas
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Pancreas
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Pancreas
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Pancreas
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Eye Morphology / Right anterior chamber depth
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.575
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Mouth morphology
|
HOM
|
12f:8m
|
|
|
NotProcessed |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Hematology / Monocyte differential count
|
HOM
|
4f:2m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.0138
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Head bobbing
|
HOM
|
12f:8m
|
|
|
NotProcessed |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Fear Conditioning / % Freezing duration context-2
|
HOM
|
12f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.798
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Heart Weight / Tibia length
|
HOM
|
10f:5m
|
Linear Mixed Model framework, LME, including Weight
|
0.133
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Spinal cord
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Spinal cord
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Spinal cord
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Spinal cord
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Hematology / Sample clotted
|
HOM
|
4f:2m
|
|
|
NotProcessed |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Body Composition (DEXA lean/fat) / Lean/Body weight
|
HOM
|
7f:3m
|
Linear Mixed Model framework, LME, not including Weight
|
0.00707
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Body Composition (DEXA lean/fat) / Lean/Body weight
|
HOM
|
5f:2m
|
Linear Mixed Model framework, LME, not including Weight
|
0.120
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
X-ray / Number of ribs right
|
HOM
|
10f:7m
|
|
|
NotProcessed |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Skin texture - ear
|
HOM
|
12f:8m
|
|
|
NotProcessed |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Body Composition (DEXA lean/fat) / Body weight
|
HOM
|
7f:6m
|
|
|
NotProcessed |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Body Composition (DEXA lean/fat) / Body weight
|
HOM
|
5f:2m
|
|
|
NotProcessed |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Shock Threshold / Jump response
|
HOM
|
12f:8m
|
|
|
NotProcessed |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Snout size
|
HOM
|
12f:8m
|
|
|
NotProcessed |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Open Field / Distance travelled - total
|
HOM
|
12f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.308
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Eye Morphology / Synechia
|
HOM
|
5f:2m
|
Fisher Exact Test framework
|
0.0234
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Electrocardiogram (ECG) / PR
|
HOM
|
5f:2m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.552
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Electrocardiogram (ECG) / PR
|
HOM
|
7f:6m
|
Linear Mixed Model framework, LME, not including Weight
|
0.951
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Auditory Brain Stem Response / 24kHz-evoked ABR Threshold
|
HOM
|
8f:5m
|
Reference Range Plus Test framework; quantile = 0.95 (Tails probability = 0.025)
|
0.0280
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Clinical Chemistry / Total cholesterol
|
HOM
|
11f:6m
|
Linear Mixed Model framework, LME, not including Weight
|
0.874
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Genitalia - size
|
HOM
|
12f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Open Field / Periphery permanence time
|
HOM
|
12f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.395
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Clinical Chemistry / Cholesterol ratio
|
HOM
|
11f:6m
|
Linear Mixed Model framework, LME, not including Weight
|
0.613
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Eye Morphology / Right inner nuclear layer
|
HOM
|
11f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.0419
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Forelimb nail - length
|
HOM
|
12f:8m
|
|
|
NotProcessed |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Clinical Chemistry / Albumin
|
HOM
|
11f:6m
|
Linear Mixed Model framework, LME, not including Weight
|
0.515
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Intraperitoneal glucose tolerance test (IPGTT) / Initial response to glucose challenge
|
HOM
|
12f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.302
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Electrocardiogram (ECG) / HR
|
HOM
|
7f:6m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.441
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Electrocardiogram (ECG) / HR
|
HOM
|
5f:2m
|
Linear Mixed Model framework, LME, not including Weight
|
0.937
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Echo / LVAWd
|
HOM
|
7f:6m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0654
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Echo / LVAWd
|
HOM
|
5f:2m
|
Linear Mixed Model framework, LME, not including Weight
|
0.772
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Aggression
|
HOM
|
12f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Open Field / Number of center entries
|
HOM
|
12f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.126
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
X-ray / Pelvis
|
HOM
|
10f:7m
|
|
|
NotProcessed |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Adrenal gland
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Adrenal gland
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Adrenal gland
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Adrenal gland
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Hindlimbs - shape
|
HOM
|
12f:8m
|
|
|
NotProcessed |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Grip Strength / Forelimb grip strength measurement mean
|
HOM
|
12f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.419
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Startle response
|
HOM
|
12f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Rotarod / Latency to fall
|
HOM
|
36f:24m
|
|
|
NotProcessed |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - BN
|
HOM
|
12f:8m
|
|
|
NotProcessed |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Eye Morphology / Eyelid morphology
|
HOM
|
12f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Forelimb digit - shape
|
HOM
|
12f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Hematology / Mean cell volume
|
HOM
|
9f:6m
|
Linear Mixed Model framework, LME, not including Weight
|
0.00
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Gall bladder
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Gall bladder
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Gall bladder
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Gall bladder
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Coat - color - back
|
HOM
|
12f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
X-ray / Femur
|
HOM
|
10f:7m
|
|
|
NotProcessed |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Challenge Whole Body Plethysmography / Tidal volume (TVb)
|
HOM
|
429f:429m
|
|
|
NotProcessed |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Eye Morphology / Cornea
|
HOM
|
5f:2m
|
Fisher Exact Test framework
|
7.96×10-05
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Eye Morphology / Left anterior chamber depth
|
HOM
|
8f:6m
|
Linear Mixed Model framework, LME, including Weight
|
0.0372
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Open Field / Center permanence time
|
HOM
|
12f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.395
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Auditory Brain Stem Response / 12kHz-evoked ABR Threshold
|
HOM
|
8f:5m
|
Reference Range Plus Test framework; quantile = 0.95 (Tails probability = 0.025)
|
0.0373
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Grip Strength / Forelimb grip strength measurement
|
HOM
|
36f:24m
|
|
|
NotProcessed |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Hindpaw - size
|
HOM
|
12f:8m
|
|
|
NotProcessed |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Open Field / Whole arena permanence
|
HOM
|
12f:8m
|
|
|
NotProcessed |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Fear Conditioning / % Freezing duration pre-cue-2
|
HOM
|
12f:8m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.0983
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Rotarod / Body weight
|
HOM
|
12f:8m
|
|
|
NotProcessed |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Hematology / Basophil cell count
|
HOM
|
4f:2m
|
|
|
NotProcessed |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Body Composition (DEXA lean/fat) / Bone Mineral Density (excluding skull)
|
HOM
|
5f:2m
|
Linear Mixed Model framework, LME, including Weight
|
0.424
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Body Composition (DEXA lean/fat) / Bone Mineral Density (excluding skull)
|
HOM
|
7f:3m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.525
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Upper lip morphology
|
HOM
|
12f:8m
|
|
|
NotProcessed |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Hematology / Red blood cell count
|
HOM
|
9f:6m
|
Linear Mixed Model framework, LME, not including Weight
|
2.72×10-12
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Locomotor activity
|
HOM
|
12f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.689
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Clinical Chemistry / LIH (Hemolysis Severity - available on AU analysers)
|
HOM
|
11f:6m
|
|
|
NotProcessed |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Skeletal muscle
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Skeletal muscle
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Skeletal muscle
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Skeletal muscle
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Indirect Calorimetry / Ambulatory activity (no. of beam cuts)
|
HOM
|
198f:176m
|
|
|
NotProcessed |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Skin texture - tail
|
HOM
|
12f:8m
|
|
|
NotProcessed |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Eye Morphology / Iris Pigmentation
|
HOM
|
5f:2m
|
Fisher Exact Test framework
|
0.130
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Vibrissae - appearance
|
HOM
|
12f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Fear Conditioning / % Freezing duration cue-1
|
HOM
|
12f:8m
|
|
|
NotProcessed |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Hot Plate / Hot plate latency
|
HOM
|
12f:8m
|
|
|
NotProcessed |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Eye Morphology / Retinal Blood Vessels
|
HOM
|
12f:8m
|
Fisher Exact Test framework
|
0.218
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI1
|
HOM
|
12f:8m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.361
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP4
|
HOM
|
12f:8m
|
|
|
NotProcessed |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Eye Morphology / Lacrimation
|
HOM
|
5f:2m
|
Fisher Exact Test framework
|
0.000820
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Fear Conditioning / Freezing duration context
|
HOM
|
36f:24m
|
|
|
NotProcessed |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
X-ray / Mandibles
|
HOM
|
10f:7m
|
|
|
NotProcessed |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Hematology / Neutrophil cell count
|
HOM
|
4f:2m
|
Linear Mixed Model framework, LME, not including Weight
|
0.101
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Eye Morphology / Right corneal thickness
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
1.00
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Seminal vesicle
|
HOM
|
f:m
|
Supplied as data
|
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Seminal vesicle
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Seminal vesicle
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Seminal vesicle
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
X-ray / Humerus
|
HOM
|
10f:7m
|
|
|
NotProcessed |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Skin color - back paws
|
HOM
|
12f:8m
|
|
|
NotProcessed |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Large intestine
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Large intestine
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Large intestine
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Large intestine
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Limb grasp
|
HOM
|
12f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Skin color - whole body
|
HOM
|
12f:8m
|
|
|
NotProcessed |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
X-ray / Number of digits
|
HOM
|
5f:2m
|
|
|
NotProcessed |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Coat - hair distribution - abdomen
|
HOM
|
12f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Coat - color pattern - head
|
HOM
|
12f:8m
|
|
|
NotProcessed |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Clinical Chemistry / Urea (Blood Urea Nitrogen - BUN)
|
HOM
|
11f:6m
|
Linear Mixed Model framework, LME, not including Weight
|
0.211
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Genitalia - presence
|
HOM
|
12f:8m
|
|
|
NotProcessed |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Open Field / Periphery resting time
|
HOM
|
12f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.930
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
X-ray / Number of lumbar vertebrae
|
HOM
|
10f:7m
|
|
|
NotProcessed |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Eye Morphology / Left outer nuclear layer
|
HOM
|
11f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.696
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Hindlimb nail - shape
|
HOM
|
12f:8m
|
|
|
NotProcessed |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
X-ray / Ulna
|
HOM
|
10f:7m
|
|
|
NotProcessed |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Coat - hair distribution - head
|
HOM
|
12f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Uterus
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Uterus
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Uterus
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Uterus
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Eye Morphology / Corneal Sclerization
|
HOM
|
5f:2m
|
Fisher Exact Test framework
|
0.000817
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Hindlimb digit - number
|
HOM
|
12f:8m
|
|
|
NotProcessed |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Clinical Chemistry / Alkaline phosphatase
|
HOM
|
5f:2m
|
Linear Mixed Model framework, LME, including Weight
|
0.0408
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Tail - length
|
HOM
|
12f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Indirect Calorimetry / Body weight after experiment
|
HOM
|
3f:2m
|
|
|
NotProcessed |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Eye Morphology / Eye Hemorrhage or Blood Presence
|
HOM
|
5f:2m
|
Fisher Exact Test framework
|
0.000588
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Hematology / Monocyte cell count
|
HOM
|
4f:2m
|
Linear Mixed Model framework, LME, not including Weight
|
0.482
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Open Field / Number of rears - total
|
HOM
|
12f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.261
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Unexpected behaviors
|
HOM
|
12f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
X-ray / Teeth
|
HOM
|
10f:7m
|
|
|
NotProcessed |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Fear Conditioning / % Freezing duration context-3
|
HOM
|
12f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.303
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - Global
|
HOM
|
12f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.540
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
X-ray / Number of ribs left
|
HOM
|
10f:7m
|
|
|
NotProcessed |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Open Field / Distance travelled
|
HOM
|
48f:32m
|
|
|
NotProcessed |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Hindlimbs - size
|
HOM
|
12f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Skin texture - front paws
|
HOM
|
12f:8m
|
|
|
NotProcessed |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Rotarod / Latency to fall mean
|
HOM
|
12f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.291
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Body Composition (DEXA lean/fat) / Bone Area
|
HOM
|
7f:3m
|
Linear Mixed Model framework, LME, including Weight
|
0.0646
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Body Composition (DEXA lean/fat) / Bone Area
|
HOM
|
5f:2m
|
Linear Mixed Model framework, LME, including Weight
|
0.603
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Body Weight / Body weight
|
HOM
|
5f:2m
|
|
|
NotProcessed |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Eye Morphology / Fusion between cornea and lens
|
HOM
|
5f:2m
|
Fisher Exact Test framework
|
0.0234
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Coat - color - head
|
HOM
|
12f:8m
|
|
|
NotProcessed |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Electrocardiogram (ECG) / QT
|
HOM
|
5f:2m
|
Linear Mixed Model framework, LME, not including Weight
|
0.219
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Electrocardiogram (ECG) / QT
|
HOM
|
7f:6m
|
Linear Mixed Model framework, LME, not including Weight
|
0.852
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Hematology / Mean corpuscular hemoglobin
|
HOM
|
9f:6m
|
Linear Mixed Model framework, LME, not including Weight
|
0.00
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Echo / LVIDs
|
HOM
|
5f:2m
|
Linear Mixed Model framework, LME, not including Weight
|
0.419
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Echo / LVIDs
|
HOM
|
7f:6m
|
Linear Mixed Model framework, LME, not including Weight
|
0.712
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Fear Conditioning / % Cue freezing total
|
HOM
|
12f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.146
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Stomach
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Stomach
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Stomach
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Stomach
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Heart Weight / Heart weight normalised against tibia length
|
HOM
|
10f:5m
|
|
|
NotProcessed |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Eye Morphology / Right outer nuclear layer
|
HOM
|
11f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.888
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Hindlimb digit - shape
|
HOM
|
12f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Forepaw - size
|
HOM
|
12f:8m
|
|
|
NotProcessed |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Intraperitoneal glucose tolerance test (IPGTT) / Fasted blood glucose concentration
|
HOM
|
12f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
9.00×10-05
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Hematology / Large Unstained Cell (LUC) differential count
|
HOM
|
4f:2m
|
Linear Mixed Model framework, LME, not including Weight
|
0.485
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Clinical Chemistry / Total bilirubin
|
HOM
|
11f:6m
|
Linear Mixed Model framework, LME, not including Weight
|
0.405
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Heart
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Heart
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Heart
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Heart
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Indirect Calorimetry / Total activity (no. of fine movement + no. of beam cuts)
|
HOM
|
198f:176m
|
|
|
NotProcessed |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Forelimbs - position
|
HOM
|
12f:8m
|
|
|
NotProcessed |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
X-ray / Fusion of ribs
|
HOM
|
10f:7m
|
|
|
NotProcessed |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Shock Threshold / Shock Intensity Flinch
|
HOM
|
12f:8m
|
|
|
NotProcessed |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP3_S
|
HOM
|
12f:8m
|
|
|
NotProcessed |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Body Composition (DEXA lean/fat) / BMC/Body weight
|
HOM
|
7f:3m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0490
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Body Composition (DEXA lean/fat) / BMC/Body weight
|
HOM
|
5f:2m
|
Linear Mixed Model framework, LME, not including Weight
|
0.466
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Trachea
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Trachea
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Trachea
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Trachea
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Lower lip morphology
|
HOM
|
12f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Skin color - front paws
|
HOM
|
12f:8m
|
|
|
NotProcessed |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Hematology / Basophil differential count
|
HOM
|
4f:2m
|
|
|
NotProcessed |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Testes
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Testes
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Testes
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Testes
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Coat - hair texture / appearance - abdomen
|
HOM
|
12f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Hot Plate / Body weight
|
HOM
|
12f:8m
|
|
|
NotProcessed |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Urinary bladder
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Urinary bladder
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Urinary bladder
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Urinary bladder
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Open Field / Center resting time
|
HOM
|
12f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.267
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP2_S
|
HOM
|
12f:8m
|
|
|
NotProcessed |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Clinical Chemistry / Glucose
|
HOM
|
11f:6m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0184
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Eye Morphology / Retinal Blood Vessels Structure
|
HOM
|
12f:8m
|
Fisher Exact Test framework
|
0.266
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Fertility of Homozygous Knock-out Mice / Gross Findings Female
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Eye Morphology / Left total retinal thickness
|
HOM
|
11f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0235
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
X-ray / Joints
|
HOM
|
10f:7m
|
|
|
NotProcessed |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Grip Strength / Forelimb and hindlimb grip strength measurement
|
HOM
|
36f:24m
|
|
|
NotProcessed |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Rotarod / Passive rotation
|
HOM
|
36f:24m
|
|
|
NotProcessed |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Fear Conditioning / Freezing duration post-us
|
HOM
|
12f:8m
|
|
|
NotProcessed |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Eye Morphology / Corneal ulcer
|
HOM
|
5f:2m
|
Fisher Exact Test framework
|
6.90×10-05
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
X-ray / Skull shape
|
HOM
|
10f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Echo / Fractional Shortening
|
HOM
|
5f:2m
|
Linear Mixed Model framework, LME, not including Weight
|
0.445
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Echo / Fractional Shortening
|
HOM
|
7f:6m
|
Linear Mixed Model framework, LME, not including Weight
|
0.899
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Forelimb nail - number
|
HOM
|
12f:8m
|
|
|
NotProcessed |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Gait
|
HOM
|
12f:8m
|
|
|
NotProcessed |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Kidney
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Kidney
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Kidney
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Kidney
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Indirect Calorimetry / Oxygen consumption
|
HOM
|
66f:44m
|
|
|
NotProcessed |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Electrocardiogram (ECG) / QRS
|
HOM
|
7f:6m
|
Linear Mixed Model framework, LME, not including Weight
|
0.672
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Electrocardiogram (ECG) / QRS
|
HOM
|
5f:2m
|
Linear Mixed Model framework, LME, not including Weight
|
0.871
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Ears
|
HOM
|
12f:8m
|
|
|
NotProcessed |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Small intestine
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Small intestine
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Small intestine
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Small intestine
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Forelimb digit - number
|
HOM
|
12f:8m
|
|
|
NotProcessed |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Tail - presence
|
HOM
|
12f:8m
|
|
|
NotProcessed |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI4
|
HOM
|
12f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.549
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Body Composition (DEXA lean/fat) / Lean mass
|
HOM
|
7f:3m
|
Linear Mixed Model framework, LME, including Weight
|
0.00325
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Body Composition (DEXA lean/fat) / Lean mass
|
HOM
|
5f:2m
|
Linear Mixed Model framework, LME, including Weight
|
0.180
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
X-ray / Tibia length
|
HOM
|
10f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.253
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP3
|
HOM
|
12f:8m
|
|
|
NotProcessed |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Eye Morphology / Pupil Light Response
|
HOM
|
5f:2m
|
Fisher Exact Test framework
|
0.136
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP4_S
|
HOM
|
12f:8m
|
|
|
NotProcessed |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Eye Morphology / Corneal opacity
|
HOM
|
5f:2m
|
Fisher Exact Test framework
|
0.000691
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Fear Conditioning / % Freezing duration pre-cue-1
|
HOM
|
12f:8m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.0583
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Open Field / Whole arena average speed
|
HOM
|
12f:8m
|
Linear Model Using Generalized Least Squares framework, GLS, including Weight
|
0.220
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
X-ray / Number of pelvic vertebrae
|
HOM
|
10f:7m
|
|
|
NotProcessed |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Ovary
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Ovary
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Ovary
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Ovary
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Challenge Whole Body Plethysmography / Frequency of breathing (f)
|
HOM
|
429f:429m
|
|
|
NotProcessed |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Combined SHIRPA and Dysmorphology / Skin color - tail
|
HOM
|
12f:8m
|
|
|
NotProcessed |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Hematology / White blood cell count
|
HOM
|
9f:6m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0241
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Eye with optic nerve
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Eye with optic nerve
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Eye with optic nerve
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |
Knstrntm1b(KOMP)Wtsi
|
ICS
|
Gross Pathology and Tissue Collection / Eye with optic nerve
|
HOM
|
f:m
|
Supplied as data
|
1.00
|
Successful |