All data for Knstrn

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Allele Center Procedure / Parameter Zygosity Mutants Statistical
Method
P Value Status Graph
Knstrntm1b(KOMP)Wtsi ICS Combined SHIRPA and Dysmorphology / Forelimb digit - size HOM 12f:8m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Knstrntm1b(KOMP)Wtsi ICS Combined SHIRPA and Dysmorphology / Tail - thickness HOM 12f:8m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Knstrntm1b(KOMP)Wtsi ICS Clinical Chemistry / Alanine aminotransferase HOM 6f:4m Mixed Model framework, generalized least squares, equation withoutWeight 0.63929 Success
Knstrntm1b(KOMP)Wtsi ICS Clinical Chemistry / Alanine aminotransferase HOM 5f:2m Not processed 1.0000 FAILED - Not enough data points in dependent variable 'IMPC_CBC_013_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Knstrntm1b(KOMP)Wtsi ICS Combined SHIRPA and Dysmorphology / Coat - hair distribution - back HOM 12f:8m Fisher Exact Test framework 1.0000 Success
Knstrntm1b(KOMP)Wtsi ICS Echo / LVPWd HOM 7f:6m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.24874 Success
Knstrntm1b(KOMP)Wtsi ICS Echo / LVPWd HOM 5f:2m Not processed 1.0000 FAILED - Not enough data points in dependent variable 'IMPC_ECH_009_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Knstrntm1b(KOMP)Wtsi ICS Eye Morphology / Bulging eye HOM 11f:7m Fisher Exact Test framework 1.0000 Success
Knstrntm1b(KOMP)Wtsi ICS Combined SHIRPA and Dysmorphology / Forelimb nail - shape HOM 5f:2m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Knstrntm1b(KOMP)Wtsi ICS Combined SHIRPA and Dysmorphology / Forelimb nail - shape HOM 7f:6m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Knstrntm1b(KOMP)Wtsi ICS Electrocardiogram (ECG) / RR HOM 7f:6m Mixed Model framework, generalized least squares, equation withoutWeight 0.16991 Success
Knstrntm1b(KOMP)Wtsi ICS Electrocardiogram (ECG) / RR HOM 5f:2m Not processed 1.0000 FAILED - Not enough data points in dependent variable 'IMPC_ECG_004_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Knstrntm1b(KOMP)Wtsi ICS Combined SHIRPA and Dysmorphology / Skin texture - whole body HOM 12f:8m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Knstrntm1b(KOMP)Wtsi ICS Eye Morphology / Left vitreous humour thickness HOM 11f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.087903 Success
Knstrntm1b(KOMP)Wtsi ICS Combined SHIRPA and Dysmorphology / Trunk curl HOM 12f:8m Fisher Exact Test framework 1.0000 Success
Knstrntm1b(KOMP)Wtsi ICS Gross Pathology and Tissue Collection / Brain HOM f:m Supplied as data Success
Knstrntm1b(KOMP)Wtsi ICS Gross Pathology and Tissue Collection / Brain HOM f:m Supplied as data Success
Knstrntm1b(KOMP)Wtsi ICS Gross Pathology and Tissue Collection / Brain HOM f:m Supplied as data Success
Knstrntm1b(KOMP)Wtsi ICS Gross Pathology and Tissue Collection / Brain HOM f:m Supplied as data Success
Knstrntm1b(KOMP)Wtsi ICS Clinical Chemistry / Creatinine HOM 6f:4m Mixed Model framework, generalized least squares, equation withoutWeight 0.20846 Success
Knstrntm1b(KOMP)Wtsi ICS Clinical Chemistry / Creatinine HOM 5f:2m Not processed 1.0000 FAILED - Not enough data points in dependent variable 'IMPC_CBC_005_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Knstrntm1b(KOMP)Wtsi ICS Eye Morphology / Iris/Pupil HOM 4f:1m Fisher Exact Test framework 1.0000 Success
Knstrntm1b(KOMP)Wtsi ICS X-ray / Number of thoracic vertebrae HOM 10f:7m Not processed 1.0000 FAILED - No variability in dependent variable 'IMPC_XRY_014_001'.
Knstrntm1b(KOMP)Wtsi ICS Hematology / Mean cell hemoglobin concentration HOM 9f:6m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.046679 Success
Knstrntm1b(KOMP)Wtsi ICS X-ray / Radius HOM 10f:7m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Knstrntm1b(KOMP)Wtsi ICS Eye Morphology / Corneal deposits HOM 4f:1m Fisher Exact Test framework 1.0000 Success
Knstrntm1b(KOMP)Wtsi ICS Indirect Calorimetry / Total food intake HOM 9f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.93643 Success
Knstrntm1b(KOMP)Wtsi ICS X-ray / Fibula HOM 10f:7m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Knstrntm1b(KOMP)Wtsi ICS Open Field / Percentage center time HOM 12f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.31974 Success
Knstrntm1b(KOMP)Wtsi ICS Hematology / Eosinophil differential count HOM 4f:2m Not processed 1.0000 FAILED - Not enough data points in dependent variable 'IMPC_HEM_035_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Knstrntm1b(KOMP)Wtsi ICS Auditory Brain Stem Response / 6kHz-evoked ABR Threshold HOM 8f:5m 1.0000 Success
Knstrntm1b(KOMP)Wtsi ICS X-ray / Shape of vertebrae HOM 10f:7m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Knstrntm1b(KOMP)Wtsi ICS Gross Pathology and Tissue Collection / Thyroid HOM f:m Supplied as data Success
Knstrntm1b(KOMP)Wtsi ICS Gross Pathology and Tissue Collection / Thyroid HOM f:m Supplied as data Success
Knstrntm1b(KOMP)Wtsi ICS Gross Pathology and Tissue Collection / Thyroid HOM f:m Supplied as data Success
Knstrntm1b(KOMP)Wtsi ICS Gross Pathology and Tissue Collection / Thyroid HOM f:m Supplied as data Success
Knstrntm1b(KOMP)Wtsi ICS Body Composition (DEXA lean/fat) / Body length HOM 7f:6m Mixed Model framework, generalized least squares, equation withoutWeight 0.33381 Success
Knstrntm1b(KOMP)Wtsi ICS Body Composition (DEXA lean/fat) / Body length HOM 5f:2m Not processed 1.0000 FAILED - Not enough data points in dependent variable 'IMPC_DXA_006_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Knstrntm1b(KOMP)Wtsi ICS X-ray / Brachydactyly HOM 5f:2m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Knstrntm1b(KOMP)Wtsi ICS Combined SHIRPA and Dysmorphology / Vibrissae - presence HOM 12f:8m Fisher Exact Test framework 0.62228 Success
Knstrntm1b(KOMP)Wtsi ICS Combined SHIRPA and Dysmorphology / Lower teeth appearance HOM 12f:8m Fisher Exact Test framework 1.0000 Success
Knstrntm1b(KOMP)Wtsi ICS X-ray / Scapulae HOM 10f:7m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Knstrntm1b(KOMP)Wtsi ICS Eye Morphology / Lens Opacity HOM 3f:1m - 1.0000 FAILED - Not enough mutant measurements (3f/1m)
Knstrntm1b(KOMP)Wtsi ICS Combined SHIRPA and Dysmorphology / Skin texture - back paws HOM 12f:8m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Knstrntm1b(KOMP)Wtsi ICS Combined SHIRPA and Dysmorphology / Forelimbs - shape HOM 12f:8m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Knstrntm1b(KOMP)Wtsi ICS Open Field / Periphery distance travelled HOM 12f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.25069 Success
Knstrntm1b(KOMP)Wtsi ICS Eye Morphology / Corneal mineralization HOM 4f:1m Fisher Exact Test framework 1.0000 Success
Knstrntm1b(KOMP)Wtsi ICS X-ray / Zygomatic bone HOM 10f:7m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Knstrntm1b(KOMP)Wtsi ICS Clinical Chemistry / Calcium HOM 6f:4m Mixed Model framework, generalized least squares, equation withoutWeight 0.39315 Success
Knstrntm1b(KOMP)Wtsi ICS Clinical Chemistry / Calcium HOM 5f:2m Not processed 1.0000 FAILED - Not enough data points in dependent variable 'IMPC_CBC_009_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Knstrntm1b(KOMP)Wtsi ICS Echo / HR HOM 7f:6m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.69416 Success
Knstrntm1b(KOMP)Wtsi ICS Echo / HR HOM 5f:2m Not processed 1.0000 FAILED - Not enough data points in dependent variable 'IMPC_ECH_013_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Knstrntm1b(KOMP)Wtsi ICS X-ray / Shape of ribs HOM 10f:7m Fisher Exact Test framework 0.39274 Success
Knstrntm1b(KOMP)Wtsi ICS Gross Pathology and Tissue Collection / Spleen HOM f:m Supplied as data Success
Knstrntm1b(KOMP)Wtsi ICS Gross Pathology and Tissue Collection / Spleen HOM f:m Supplied as data Success
Knstrntm1b(KOMP)Wtsi ICS Gross Pathology and Tissue Collection / Spleen HOM f:m Supplied as data Success
Knstrntm1b(KOMP)Wtsi ICS Gross Pathology and Tissue Collection / Spleen HOM f:m Supplied as data Success
Knstrntm1b(KOMP)Wtsi ICS Gross Pathology and Tissue Collection / Epididymis HOM f:m Supplied as data Success
Knstrntm1b(KOMP)Wtsi ICS Gross Pathology and Tissue Collection / Epididymis HOM f:m Supplied as data Success
Knstrntm1b(KOMP)Wtsi ICS Gross Pathology and Tissue Collection / Epididymis HOM f:m Supplied as data Success
Knstrntm1b(KOMP)Wtsi ICS Gross Pathology and Tissue Collection / Epididymis HOM f:m Supplied as data Success
Knstrntm1b(KOMP)Wtsi ICS Combined SHIRPA and Dysmorphology / Contact righting HOM 12f:8m Fisher Exact Test framework 1.0000 Success
Knstrntm1b(KOMP)Wtsi ICS Hematology / Hematocrit HOM 9f:6m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.00060417 Success
Knstrntm1b(KOMP)Wtsi ICS Combined SHIRPA and Dysmorphology / Hindlimb nail - number HOM 5f:2m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Knstrntm1b(KOMP)Wtsi ICS Combined SHIRPA and Dysmorphology / Skin color - ear HOM 12f:8m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Knstrntm1b(KOMP)Wtsi ICS Grip Strength / Forelimb and hindlimb grip strength normalised against body weight HOM 12f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.12088 Success
Knstrntm1b(KOMP)Wtsi ICS Combined SHIRPA and Dysmorphology / Hindlimb nail - number HOM 7f:6m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Knstrntm1b(KOMP)Wtsi ICS Gross Pathology and Tissue Collection / Esophagus HOM f:m Supplied as data Success
Knstrntm1b(KOMP)Wtsi ICS Gross Pathology and Tissue Collection / Esophagus HOM f:m Supplied as data Success
Knstrntm1b(KOMP)Wtsi ICS Gross Pathology and Tissue Collection / Esophagus HOM f:m Supplied as data Success
Knstrntm1b(KOMP)Wtsi ICS Gross Pathology and Tissue Collection / Esophagus HOM f:m Supplied as data Success
Knstrntm1b(KOMP)Wtsi ICS Combined SHIRPA and Dysmorphology / Coat - hair texture / appearance - head HOM 12f:8m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Knstrntm1b(KOMP)Wtsi ICS Intraperitoneal glucose tolerance test (IPGTT) / Area under glucose response curve HOM 12f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.56879 Success
Knstrntm1b(KOMP)Wtsi ICS Combined SHIRPA and Dysmorphology / Coat - color - abdomen HOM 12f:8m Fisher Exact Test framework 1.0000 Success
Knstrntm1b(KOMP)Wtsi ICS Eye Morphology / Pupil Dilation HOM 4f:1m Fisher Exact Test framework 1.0000 Success
Knstrntm1b(KOMP)Wtsi ICS Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI3 HOM 7f:6m Mixed Model framework, generalized least squares, equation withoutWeight 0.50937 Success
Knstrntm1b(KOMP)Wtsi ICS Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI3 HOM 5f:2m Not processed 1.0000 FAILED - Not enough data points in dependent variable 'IMPC_ACS_035_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Knstrntm1b(KOMP)Wtsi ICS Body Composition (DEXA lean/fat) / Fat mass HOM 5f:2m Not processed 1.0000 FAILED - Not enough data points in dependent variable 'IMPC_DXA_002_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Knstrntm1b(KOMP)Wtsi ICS Body Composition (DEXA lean/fat) / Fat mass HOM 7f:3m Not processed 1.0000 FAILED - Not enough data points in dependent variable 'IMPC_DXA_002_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Knstrntm1b(KOMP)Wtsi ICS Auditory Brain Stem Response / 30kHz-evoked ABR Threshold HOM 8f:5m 0.059811 Success
Knstrntm1b(KOMP)Wtsi ICS Eye Morphology / Left inner nuclear layer HOM 11f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0081806 Success
Knstrntm1b(KOMP)Wtsi ICS Clinical Chemistry / Phosphorus HOM 6f:4m Mixed Model framework, generalized least squares, equation withoutWeight 0.013073 Success
Knstrntm1b(KOMP)Wtsi ICS Clinical Chemistry / Phosphorus HOM 5f:2m Not processed 1.0000 FAILED - Not enough data points in dependent variable 'IMPC_CBC_010_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Knstrntm1b(KOMP)Wtsi ICS Combined SHIRPA and Dysmorphology / Hindpaw - shape HOM 7f:6m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Knstrntm1b(KOMP)Wtsi ICS Combined SHIRPA and Dysmorphology / Hindpaw - shape HOM 5f:2m Fisher Exact Test framework 1.0000 Success
Knstrntm1b(KOMP)Wtsi ICS Combined SHIRPA and Dysmorphology / Tremor HOM 12f:8m Fisher Exact Test framework 2.1150E-05 Success
Knstrntm1b(KOMP)Wtsi ICS Viability Primary Screen / Outcome HOM 107f:97m Supplied as data Success
Knstrntm1b(KOMP)Wtsi ICS Combined SHIRPA and Dysmorphology / Genitalia - morphology HOM 12f:8m Fisher Exact Test framework 1.0000 Success
Knstrntm1b(KOMP)Wtsi ICS Gross Pathology and Tissue Collection / Lymph node HOM f:m Supplied as data Success
Knstrntm1b(KOMP)Wtsi ICS Gross Pathology and Tissue Collection / Lymph node HOM f:m Supplied as data Success
Knstrntm1b(KOMP)Wtsi ICS Gross Pathology and Tissue Collection / Lymph node HOM f:m Supplied as data Success
Knstrntm1b(KOMP)Wtsi ICS Gross Pathology and Tissue Collection / Lymph node HOM f:m Supplied as data Success
Knstrntm1b(KOMP)Wtsi ICS Hematology / Large Unstained Cell (LUC) count HOM 4f:2m Not processed 1.0000 FAILED - Not enough data points in dependent variable 'IMPC_HEM_039_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Knstrntm1b(KOMP)Wtsi ICS Indirect Calorimetry / Total water intake HOM 9f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.015340 Success
Knstrntm1b(KOMP)Wtsi ICS Combined SHIRPA and Dysmorphology / Head morphology HOM 12f:8m Fisher Exact Test framework 1.0000 Success
Knstrntm1b(KOMP)Wtsi ICS Hematology / Lymphocyte cell count HOM 4f:2m Not processed 1.0000 FAILED - Not enough data points in dependent variable 'IMPC_HEM_032_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Knstrntm1b(KOMP)Wtsi ICS Electrocardiogram (ECG) / ST HOM 7f:6m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.48780 Success
Knstrntm1b(KOMP)Wtsi ICS Electrocardiogram (ECG) / ST HOM 5f:2m Not processed 1.0000 FAILED - Not enough data points in dependent variable 'IMPC_ECG_008_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Knstrntm1b(KOMP)Wtsi ICS Indirect Calorimetry / Respiratory Exchange Ratio HOM 3f:2m Not processed 1.0000 FAILED - Not enough mutant measurements (3f/2m)
Knstrntm1b(KOMP)Wtsi ICS Combined SHIRPA and Dysmorphology / Upper teeth appearance HOM 12f:8m Fisher Exact Test framework 1.0000 Success
Knstrntm1b(KOMP)Wtsi ICS Open Field / Center distance travelled HOM 12f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.70051 Success
Knstrntm1b(KOMP)Wtsi ICS Auditory Brain Stem Response / 18kHz-evoked ABR Threshold HOM 8f:5m 1.0000 Success
Knstrntm1b(KOMP)Wtsi ICS Eye Morphology / Corneal vascularization HOM 4f:1m Fisher Exact Test framework 1.0000 Success
Knstrntm1b(KOMP)Wtsi ICS Eye Morphology / Retinal Blood Vessels Pattern HOM 11f:7m Fisher Exact Test framework 0.43656 Success
Knstrntm1b(KOMP)Wtsi ICS Clinical Chemistry / Triglycerides HOM 6f:4m Mixed Model framework, generalized least squares, equation withoutWeight 0.0065882 Success
Knstrntm1b(KOMP)Wtsi ICS Clinical Chemistry / Triglycerides HOM 5f:2m Not processed 1.0000 FAILED - Not enough data points in dependent variable 'IMPC_CBC_017_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Knstrntm1b(KOMP)Wtsi ICS Eye Morphology / Right total retinal thickness HOM 11f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.94014 Success
Knstrntm1b(KOMP)Wtsi ICS X-ray / Clavicle HOM 10f:7m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Knstrntm1b(KOMP)Wtsi ICS Hematology / Platelet count HOM 9f:6m Mixed Model framework, linear mixed-effects model, equation withoutWeight 2.0538E-13 Success
Knstrntm1b(KOMP)Wtsi ICS Combined SHIRPA and Dysmorphology / Activity (body position) HOM 12f:8m Fisher Exact Test framework 0.67555 Success
Knstrntm1b(KOMP)Wtsi ICS Gross Pathology and Tissue Collection / Liver HOM f:m Supplied as data Success
Knstrntm1b(KOMP)Wtsi ICS Gross Pathology and Tissue Collection / Liver HOM f:m Supplied as data Success
Knstrntm1b(KOMP)Wtsi ICS Gross Pathology and Tissue Collection / Liver HOM f:m Supplied as data Success
Knstrntm1b(KOMP)Wtsi ICS Gross Pathology and Tissue Collection / Liver HOM f:m Supplied as data Success
Knstrntm1b(KOMP)Wtsi ICS Combined SHIRPA and Dysmorphology / Hindlimb digit - size HOM 12f:8m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Knstrntm1b(KOMP)Wtsi ICS X-ray / Digit integrity HOM 5f:2m Fisher Exact Test framework 1.0000 Success
Knstrntm1b(KOMP)Wtsi ICS Gross Pathology and Tissue Collection / Thymus HOM f:m Supplied as data Success
Knstrntm1b(KOMP)Wtsi ICS Gross Pathology and Tissue Collection / Thymus HOM f:m Supplied as data Success
Knstrntm1b(KOMP)Wtsi ICS Gross Pathology and Tissue Collection / Thymus HOM f:m Supplied as data Success
Knstrntm1b(KOMP)Wtsi ICS Gross Pathology and Tissue Collection / Thymus HOM f:m Supplied as data Success
Knstrntm1b(KOMP)Wtsi ICS Combined SHIRPA and Dysmorphology / Skin texture - snout HOM 12f:8m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Knstrntm1b(KOMP)Wtsi ICS Clinical Chemistry / Total protein HOM 6f:4m Mixed Model framework, generalized least squares, equation withoutWeight 0.22857 Success
Knstrntm1b(KOMP)Wtsi ICS Clinical Chemistry / Total protein HOM 5f:2m Not processed 1.0000 FAILED - Not enough data points in dependent variable 'IMPC_CBC_006_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Knstrntm1b(KOMP)Wtsi ICS Eye Morphology / Pupil Position HOM 4f:1m Fisher Exact Test framework 1.0000 Success
Knstrntm1b(KOMP)Wtsi ICS Combined SHIRPA and Dysmorphology / Hindlimbs - position HOM 12f:8m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Knstrntm1b(KOMP)Wtsi ICS Body Composition (DEXA lean/fat) / Fat/Body weight HOM 7f:3m Not processed 1.0000 FAILED - Not enough data points in dependent variable 'IMPC_DXA_009_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Knstrntm1b(KOMP)Wtsi ICS Body Composition (DEXA lean/fat) / Fat/Body weight HOM 5f:2m Not processed 1.0000 FAILED - Not enough data points in dependent variable 'IMPC_DXA_009_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Knstrntm1b(KOMP)Wtsi ICS X-ray / Number of cervical vertebrae HOM 10f:7m Not processed 1.0000 FAILED - No variability in dependent variable 'IMPC_XRY_013_001'.
Knstrntm1b(KOMP)Wtsi ICS Open Field / Latency to center entry HOM 12f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.50336 Success
Knstrntm1b(KOMP)Wtsi ICS Eye Morphology / Eyelid closure HOM 12f:8m Fisher Exact Test framework 0.0076082 Success
Knstrntm1b(KOMP)Wtsi ICS Combined SHIRPA and Dysmorphology / Forelimbs - size HOM 12f:8m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Knstrntm1b(KOMP)Wtsi ICS Gross Pathology and Tissue Collection / Mammary gland HOM f:m Supplied as data Success
Knstrntm1b(KOMP)Wtsi ICS Gross Pathology and Tissue Collection / Mammary gland HOM f:m Supplied as data Success
Knstrntm1b(KOMP)Wtsi ICS Gross Pathology and Tissue Collection / Mammary gland HOM f:m Supplied as data Success
Knstrntm1b(KOMP)Wtsi ICS Gross Pathology and Tissue Collection / Mammary gland HOM f:m Supplied as data Success
Knstrntm1b(KOMP)Wtsi ICS Echo / LVIDd HOM 7f:6m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.43415 Success
Knstrntm1b(KOMP)Wtsi ICS Echo / LVIDd HOM 5f:2m Not processed 1.0000 FAILED - Not enough data points in dependent variable 'IMPC_ECH_008_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Knstrntm1b(KOMP)Wtsi ICS X-ray / Fusion of vertebrae HOM 10f:7m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Knstrntm1b(KOMP)Wtsi ICS Combined SHIRPA and Dysmorphology / Tail - morphology HOM 12f:8m Fisher Exact Test framework 1.0000 Success
Knstrntm1b(KOMP)Wtsi ICS X-ray / Tibia HOM 10f:7m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Knstrntm1b(KOMP)Wtsi ICS Combined SHIRPA and Dysmorphology / Coat - color pattern - abdomen HOM 12f:8m Fisher Exact Test framework 1.0000 Success
Knstrntm1b(KOMP)Wtsi ICS Eye Morphology / Iris transilumination HOM 4f:1m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Knstrntm1b(KOMP)Wtsi ICS Clinical Chemistry / Aspartate aminotransferase HOM 6f:4m Mixed Model framework, generalized least squares, equation withoutWeight 0.94687 Success
Knstrntm1b(KOMP)Wtsi ICS Clinical Chemistry / Aspartate aminotransferase HOM 5f:2m Not processed 1.0000 FAILED - Not enough data points in dependent variable 'IMPC_CBC_012_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Knstrntm1b(KOMP)Wtsi ICS Combined SHIRPA and Dysmorphology / Hindlimb nail - length HOM 5f:2m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Knstrntm1b(KOMP)Wtsi ICS Combined SHIRPA and Dysmorphology / Hindlimb nail - length HOM 7f:6m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Knstrntm1b(KOMP)Wtsi ICS Hematology / Eosinophil cell count HOM 4f:2m Not processed 1.0000 FAILED - Not enough data points in dependent variable 'IMPC_HEM_036_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Knstrntm1b(KOMP)Wtsi ICS Combined SHIRPA and Dysmorphology / Vocalization HOM 12f:8m Fisher Exact Test framework 0.49856 Success
Knstrntm1b(KOMP)Wtsi ICS Grip Strength / Forelimb and hindlimb grip strength measurement mean HOM 12f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.14511 Success
Knstrntm1b(KOMP)Wtsi ICS Hematology / Hemoglobin HOM 9f:6m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0052485 Success
Knstrntm1b(KOMP)Wtsi ICS Open Field / Whole arena resting time HOM 12f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.95866 Success
Knstrntm1b(KOMP)Wtsi ICS X-ray / Syndactylism HOM 5f:2m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Knstrntm1b(KOMP)Wtsi ICS Eye Morphology / Vitreous HOM 11f:7m Fisher Exact Test framework 0.54507 Success
Knstrntm1b(KOMP)Wtsi ICS Combined SHIRPA and Dysmorphology / Teeth presence HOM 12f:8m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Knstrntm1b(KOMP)Wtsi ICS Eye Morphology / Lens HOM 3f:1m - 1.0000 FAILED - Not enough mutant measurements (3f/1m)
Knstrntm1b(KOMP)Wtsi ICS Electrocardiogram (ECG) / QTc HOM 7f:6m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.49432 Success
Knstrntm1b(KOMP)Wtsi ICS Electrocardiogram (ECG) / QTc HOM 5f:2m Not processed 1.0000 FAILED - Not enough data points in dependent variable 'IMPC_ECG_009_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Knstrntm1b(KOMP)Wtsi ICS Grip Strength / Forelimb grip strength normalised against body weight HOM 12f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.42829 Success
Knstrntm1b(KOMP)Wtsi ICS Combined SHIRPA and Dysmorphology / Head size HOM 12f:8m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Knstrntm1b(KOMP)Wtsi ICS Eye Morphology / Left corneal thickness HOM 8f:6m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.89696 Success
Knstrntm1b(KOMP)Wtsi ICS Eye Morphology / Optic Disc HOM 11f:7m Fisher Exact Test framework 1.0000 Success
Knstrntm1b(KOMP)Wtsi ICS Combined SHIRPA and Dysmorphology / Coat - color pattern - back HOM 12f:8m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Knstrntm1b(KOMP)Wtsi ICS Open Field / Center average speed HOM 12f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.12530 Success
Knstrntm1b(KOMP)Wtsi ICS Eye Morphology / Narrow eye opening HOM 11f:7m Fisher Exact Test framework 1.0000 Success
Knstrntm1b(KOMP)Wtsi ICS Heart Weight / Heart weight HOM 11f:6m Mixed Model framework, linear mixed-effects model, equation withWeight 0.68051 Success
Knstrntm1b(KOMP)Wtsi ICS Combined SHIRPA and Dysmorphology / Forepaw - shape HOM 7f:6m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Knstrntm1b(KOMP)Wtsi ICS Combined SHIRPA and Dysmorphology / Forepaw - shape HOM 5f:2m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Knstrntm1b(KOMP)Wtsi ICS Body Composition (DEXA lean/fat) / Bone Mineral Content (excluding skull) HOM 5f:2m Not processed 1.0000 FAILED - Not enough data points in dependent variable 'IMPC_DXA_005_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Knstrntm1b(KOMP)Wtsi ICS Body Composition (DEXA lean/fat) / Bone Mineral Content (excluding skull) HOM 7f:3m Not processed 1.0000 FAILED - Not enough data points in dependent variable 'IMPC_DXA_005_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Knstrntm1b(KOMP)Wtsi ICS Hematology / Neutrophil differential count HOM 4f:2m Not processed 1.0000 FAILED - Not enough data points in dependent variable 'IMPC_HEM_029_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Knstrntm1b(KOMP)Wtsi ICS Combined SHIRPA and Dysmorphology / Skin color - snout HOM 12f:8m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Knstrntm1b(KOMP)Wtsi ICS Gross Pathology and Tissue Collection / Prostate HOM f:m Supplied as data Success
Knstrntm1b(KOMP)Wtsi ICS Gross Pathology and Tissue Collection / Prostate HOM f:m Supplied as data Success
Knstrntm1b(KOMP)Wtsi ICS Gross Pathology and Tissue Collection / Prostate HOM f:m Supplied as data Success
Knstrntm1b(KOMP)Wtsi ICS Gross Pathology and Tissue Collection / Prostate HOM f:m Supplied as data Success
Knstrntm1b(KOMP)Wtsi ICS Combined SHIRPA and Dysmorphology / Coat - hair texture / appearance - back HOM 12f:8m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Knstrntm1b(KOMP)Wtsi ICS Gross Pathology and Tissue Collection / Lung HOM f:m Supplied as data Success
Knstrntm1b(KOMP)Wtsi ICS Gross Pathology and Tissue Collection / Lung HOM f:m Supplied as data Success
Knstrntm1b(KOMP)Wtsi ICS Gross Pathology and Tissue Collection / Lung HOM f:m Supplied as data Success
Knstrntm1b(KOMP)Wtsi ICS Gross Pathology and Tissue Collection / Lung HOM f:m Supplied as data Success
Knstrntm1b(KOMP)Wtsi ICS Gross Pathology and Tissue Collection / Skin HOM f:m Supplied as data Success
Knstrntm1b(KOMP)Wtsi ICS Gross Pathology and Tissue Collection / Skin HOM f:m Supplied as data Success
Knstrntm1b(KOMP)Wtsi ICS Gross Pathology and Tissue Collection / Skin HOM f:m Supplied as data Success
Knstrntm1b(KOMP)Wtsi ICS Gross Pathology and Tissue Collection / Skin HOM f:m Supplied as data Success
Knstrntm1b(KOMP)Wtsi ICS Clinical Chemistry / HDL-cholesterol HOM 6f:4m Mixed Model framework, generalized least squares, equation withoutWeight 0.91110 Success
Knstrntm1b(KOMP)Wtsi ICS Clinical Chemistry / HDL-cholesterol HOM 5f:2m Not processed 1.0000 FAILED - Not enough data points in dependent variable 'IMPC_CBC_016_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Knstrntm1b(KOMP)Wtsi ICS Eye Morphology / Persistence of hyaloid vascular system HOM 11f:7m Fisher Exact Test framework 0.64846 Success
Knstrntm1b(KOMP)Wtsi ICS Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI2 HOM 7f:6m Mixed Model framework, generalized least squares, equation withoutWeight 0.54853 Success
Knstrntm1b(KOMP)Wtsi ICS Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI2 HOM 5f:2m Not processed 1.0000 FAILED - Not enough data points in dependent variable 'IMPC_ACS_034_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Knstrntm1b(KOMP)Wtsi ICS Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - S HOM 7f:6m Mixed Model framework, generalized least squares, equation withoutWeight 0.97960 Success
Knstrntm1b(KOMP)Wtsi ICS Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - S HOM 5f:2m Not processed 1.0000 FAILED - Not enough data points in dependent variable 'IMPC_ACS_006_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Knstrntm1b(KOMP)Wtsi ICS Eye Morphology / Pupil Shape HOM 4f:1m Fisher Exact Test framework 1.0000 Success
Knstrntm1b(KOMP)Wtsi ICS Open Field / Periphery average speed HOM 12f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.12263 Success
Knstrntm1b(KOMP)Wtsi ICS Fertility of Homozygous Knock-out Mice / Gross Findings Male HOM f:m Supplied as data Success
Knstrntm1b(KOMP)Wtsi ICS Eye Morphology / Eye HOM 12f:8m Fisher Exact Test framework 0.0097928 Success
Knstrntm1b(KOMP)Wtsi ICS X-ray / Processes on vertebrae HOM 10f:7m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Knstrntm1b(KOMP)Wtsi ICS Eye Morphology / Right vitreous humor thickness HOM 11f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.049041 Success
Knstrntm1b(KOMP)Wtsi ICS X-ray / Maxilla/Pre-maxilla HOM 10f:7m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Knstrntm1b(KOMP)Wtsi ICS Hematology / Lymphocyte differential count HOM 4f:2m Not processed 1.0000 FAILED - Not enough data points in dependent variable 'IMPC_HEM_031_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Knstrntm1b(KOMP)Wtsi ICS Gross Pathology and Tissue Collection / Pancreas HOM f:m Supplied as data Success
Knstrntm1b(KOMP)Wtsi ICS Gross Pathology and Tissue Collection / Pancreas HOM f:m Supplied as data Success
Knstrntm1b(KOMP)Wtsi ICS Gross Pathology and Tissue Collection / Pancreas HOM f:m Supplied as data Success
Knstrntm1b(KOMP)Wtsi ICS Gross Pathology and Tissue Collection / Pancreas HOM f:m Supplied as data Success
Knstrntm1b(KOMP)Wtsi ICS Eye Morphology / Right anterior chamber depth HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.66468 Success
Knstrntm1b(KOMP)Wtsi ICS Combined SHIRPA and Dysmorphology / Mouth morphology HOM 12f:8m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Knstrntm1b(KOMP)Wtsi ICS Hematology / Monocyte differential count HOM 4f:2m Not processed 1.0000 FAILED - Not enough data points in dependent variable 'IMPC_HEM_033_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Knstrntm1b(KOMP)Wtsi ICS Combined SHIRPA and Dysmorphology / Head bobbing HOM 12f:8m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Knstrntm1b(KOMP)Wtsi ICS Heart Weight / Tibia length HOM 10f:5m Mixed Model framework, linear mixed-effects model, equation withWeight 0.37746 Success
Knstrntm1b(KOMP)Wtsi ICS Gross Pathology and Tissue Collection / Spinal cord HOM f:m Supplied as data Success
Knstrntm1b(KOMP)Wtsi ICS Gross Pathology and Tissue Collection / Spinal cord HOM f:m Supplied as data Success
Knstrntm1b(KOMP)Wtsi ICS Gross Pathology and Tissue Collection / Spinal cord HOM f:m Supplied as data Success
Knstrntm1b(KOMP)Wtsi ICS Gross Pathology and Tissue Collection / Spinal cord HOM f:m Supplied as data Success
Knstrntm1b(KOMP)Wtsi ICS Body Composition (DEXA lean/fat) / Lean/Body weight HOM 7f:3m Not processed 1.0000 FAILED - Not enough data points in dependent variable 'IMPC_DXA_008_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Knstrntm1b(KOMP)Wtsi ICS Body Composition (DEXA lean/fat) / Lean/Body weight HOM 5f:2m Not processed 1.0000 FAILED - Not enough data points in dependent variable 'IMPC_DXA_008_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Knstrntm1b(KOMP)Wtsi ICS X-ray / Number of ribs right HOM 10f:7m Not processed 1.0000 FAILED - No variability in dependent variable 'IMPC_XRY_008_001'.
Knstrntm1b(KOMP)Wtsi ICS Combined SHIRPA and Dysmorphology / Skin texture - ear HOM 12f:8m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Knstrntm1b(KOMP)Wtsi ICS Open Field / Distance travelled - total HOM 12f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.43049 Success
Knstrntm1b(KOMP)Wtsi ICS Combined SHIRPA and Dysmorphology / Snout size HOM 12f:8m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Knstrntm1b(KOMP)Wtsi ICS Electrocardiogram (ECG) / PR HOM 7f:6m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.99198 Success
Knstrntm1b(KOMP)Wtsi ICS Electrocardiogram (ECG) / PR HOM 5f:2m Not processed 1.0000 FAILED - Not enough data points in dependent variable 'IMPC_ECG_006_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Knstrntm1b(KOMP)Wtsi ICS Eye Morphology / Synechia HOM 3f:1m - 1.0000 FAILED - Not enough mutant measurements (3f/1m)
Knstrntm1b(KOMP)Wtsi ICS Auditory Brain Stem Response / 24kHz-evoked ABR Threshold HOM 8f:5m 1.0000 Success
Knstrntm1b(KOMP)Wtsi ICS Clinical Chemistry / Total cholesterol HOM 6f:4m Mixed Model framework, generalized least squares, equation withoutWeight 0.53003 Success
Knstrntm1b(KOMP)Wtsi ICS Clinical Chemistry / Total cholesterol HOM 5f:2m Not processed 1.0000 FAILED - Not enough data points in dependent variable 'IMPC_CBC_015_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Knstrntm1b(KOMP)Wtsi ICS Combined SHIRPA and Dysmorphology / Genitalia - size HOM 12f:8m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Knstrntm1b(KOMP)Wtsi ICS Open Field / Periphery permanence time HOM 12f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.31968 Success
Knstrntm1b(KOMP)Wtsi ICS Eye Morphology / Right inner nuclear layer HOM 11f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.00048633 Success
Knstrntm1b(KOMP)Wtsi ICS Clinical Chemistry / Albumin HOM 6f:4m Mixed Model framework, generalized least squares, equation withoutWeight 0.22809 Success
Knstrntm1b(KOMP)Wtsi ICS Clinical Chemistry / Albumin HOM 5f:2m Not processed 1.0000 FAILED - Not enough data points in dependent variable 'IMPC_CBC_007_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Knstrntm1b(KOMP)Wtsi ICS Combined SHIRPA and Dysmorphology / Forelimb nail - length HOM 5f:2m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Knstrntm1b(KOMP)Wtsi ICS Combined SHIRPA and Dysmorphology / Forelimb nail - length HOM 7f:6m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Knstrntm1b(KOMP)Wtsi ICS Electrocardiogram (ECG) / HR HOM 7f:6m Mixed Model framework, generalized least squares, equation withoutWeight 0.20030 Success
Knstrntm1b(KOMP)Wtsi ICS Electrocardiogram (ECG) / HR HOM 5f:2m Not processed 1.0000 FAILED - Not enough data points in dependent variable 'IMPC_ECG_002_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Knstrntm1b(KOMP)Wtsi ICS Intraperitoneal glucose tolerance test (IPGTT) / Initial response to glucose challenge HOM 12f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.24367 Success
Knstrntm1b(KOMP)Wtsi ICS Echo / LVAWd HOM 7f:6m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.028533 Success
Knstrntm1b(KOMP)Wtsi ICS Echo / LVAWd HOM 5f:2m Not processed 1.0000 FAILED - Not enough data points in dependent variable 'IMPC_ECH_007_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Knstrntm1b(KOMP)Wtsi ICS Combined SHIRPA and Dysmorphology / Aggression HOM 12f:8m Fisher Exact Test framework 1.0000 Success
Knstrntm1b(KOMP)Wtsi ICS Open Field / Number of center entries HOM 12f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.35030 Success
Knstrntm1b(KOMP)Wtsi ICS X-ray / Pelvis HOM 10f:7m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Knstrntm1b(KOMP)Wtsi ICS Gross Pathology and Tissue Collection / Adrenal gland HOM f:m Supplied as data Success
Knstrntm1b(KOMP)Wtsi ICS Gross Pathology and Tissue Collection / Adrenal gland HOM f:m Supplied as data Success
Knstrntm1b(KOMP)Wtsi ICS Gross Pathology and Tissue Collection / Adrenal gland HOM f:m Supplied as data Success
Knstrntm1b(KOMP)Wtsi ICS Gross Pathology and Tissue Collection / Adrenal gland HOM f:m Supplied as data Success
Knstrntm1b(KOMP)Wtsi ICS Grip Strength / Forelimb grip strength measurement mean HOM 12f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.29638 Success
Knstrntm1b(KOMP)Wtsi ICS Combined SHIRPA and Dysmorphology / Hindlimbs - shape HOM 12f:8m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Knstrntm1b(KOMP)Wtsi ICS Combined SHIRPA and Dysmorphology / Startle response HOM 12f:8m Fisher Exact Test framework 1.0000 Success
Knstrntm1b(KOMP)Wtsi ICS Eye Morphology / Eyelid morphology HOM 12f:8m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Knstrntm1b(KOMP)Wtsi ICS Combined SHIRPA and Dysmorphology / Forelimb digit - shape HOM 5f:2m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Knstrntm1b(KOMP)Wtsi ICS Hematology / Mean cell volume HOM 9f:6m Mixed Model framework, linear mixed-effects model, equation withoutWeight 1.1938E-49 Success
Knstrntm1b(KOMP)Wtsi ICS Gross Pathology and Tissue Collection / Gall bladder HOM f:m Supplied as data Success
Knstrntm1b(KOMP)Wtsi ICS Gross Pathology and Tissue Collection / Gall bladder HOM f:m Supplied as data Success
Knstrntm1b(KOMP)Wtsi ICS Gross Pathology and Tissue Collection / Gall bladder HOM f:m Supplied as data Success
Knstrntm1b(KOMP)Wtsi ICS Gross Pathology and Tissue Collection / Gall bladder HOM f:m Supplied as data Success
Knstrntm1b(KOMP)Wtsi ICS Combined SHIRPA and Dysmorphology / Coat - color - back HOM 12f:8m Fisher Exact Test framework 1.0000 Success
Knstrntm1b(KOMP)Wtsi ICS X-ray / Femur HOM 10f:7m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Knstrntm1b(KOMP)Wtsi ICS Combined SHIRPA and Dysmorphology / Forelimb digit - shape HOM 7f:6m Fisher Exact Test framework 1.0000 Success
Knstrntm1b(KOMP)Wtsi ICS Eye Morphology / Cornea HOM 5f:1m Fisher Exact Test framework 0.0030789 Success
Knstrntm1b(KOMP)Wtsi ICS Eye Morphology / Left anterior chamber depth HOM 8f:6m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.025402 Success
Knstrntm1b(KOMP)Wtsi ICS Open Field / Center permanence time HOM 12f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.31974 Success
Knstrntm1b(KOMP)Wtsi ICS Auditory Brain Stem Response / 12kHz-evoked ABR Threshold HOM 8f:5m 1.0000 Success
Knstrntm1b(KOMP)Wtsi ICS Combined SHIRPA and Dysmorphology / Hindpaw - size HOM 7f:6m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Knstrntm1b(KOMP)Wtsi ICS Combined SHIRPA and Dysmorphology / Hindpaw - size HOM 5f:2m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Knstrntm1b(KOMP)Wtsi ICS Hematology / Basophil cell count HOM 4f:2m Not processed 1.0000 FAILED - Insufficient variability in dependent variable 'IMPC_HEM_037_001' for MM/TF framework. Fisher Exact Test can be better way to do the analysis.
Knstrntm1b(KOMP)Wtsi ICS Body Composition (DEXA lean/fat) / Bone Mineral Density (excluding skull) HOM 5f:2m Not processed 1.0000 FAILED - Not enough data points in dependent variable 'IMPC_DXA_004_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Knstrntm1b(KOMP)Wtsi ICS Body Composition (DEXA lean/fat) / Bone Mineral Density (excluding skull) HOM 7f:3m Not processed 1.0000 FAILED - Not enough data points in dependent variable 'IMPC_DXA_004_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Knstrntm1b(KOMP)Wtsi ICS Combined SHIRPA and Dysmorphology / Upper lip morphology HOM 12f:8m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Knstrntm1b(KOMP)Wtsi ICS Hematology / Red blood cell count HOM 9f:6m Mixed Model framework, linear mixed-effects model, equation withoutWeight 5.5590E-16 Success
Knstrntm1b(KOMP)Wtsi ICS Combined SHIRPA and Dysmorphology / Locomotor activity HOM 12f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.77993 Success
Knstrntm1b(KOMP)Wtsi ICS Gross Pathology and Tissue Collection / Skeletal muscle HOM f:m Supplied as data Success
Knstrntm1b(KOMP)Wtsi ICS Gross Pathology and Tissue Collection / Skeletal muscle HOM f:m Supplied as data Success
Knstrntm1b(KOMP)Wtsi ICS Gross Pathology and Tissue Collection / Skeletal muscle HOM f:m Supplied as data Success
Knstrntm1b(KOMP)Wtsi ICS Gross Pathology and Tissue Collection / Skeletal muscle HOM f:m Supplied as data Success
Knstrntm1b(KOMP)Wtsi ICS Combined SHIRPA and Dysmorphology / Skin texture - tail HOM 12f:8m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Knstrntm1b(KOMP)Wtsi ICS Eye Morphology / Iris Pigmentation HOM 4f:1m Fisher Exact Test framework 1.0000 Success
Knstrntm1b(KOMP)Wtsi ICS Combined SHIRPA and Dysmorphology / Vibrissae - appearance HOM 12f:8m Fisher Exact Test framework 1.0000 Success
Knstrntm1b(KOMP)Wtsi ICS Eye Morphology / Retinal Blood Vessels HOM 11f:7m Fisher Exact Test framework 0.40574 Success
Knstrntm1b(KOMP)Wtsi ICS Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI1 HOM 7f:6m Mixed Model framework, generalized least squares, equation withoutWeight 0.95561 Success
Knstrntm1b(KOMP)Wtsi ICS Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI1 HOM 5f:2m Not processed 1.0000 FAILED - Not enough data points in dependent variable 'IMPC_ACS_033_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Knstrntm1b(KOMP)Wtsi ICS Eye Morphology / Lacrimation HOM 4f:1m Fisher Exact Test framework 1.0000 Success
Knstrntm1b(KOMP)Wtsi ICS X-ray / Mandibles HOM 10f:7m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Knstrntm1b(KOMP)Wtsi ICS Eye Morphology / Right corneal thickness HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.19509 Success
Knstrntm1b(KOMP)Wtsi ICS Hematology / Neutrophil cell count HOM 4f:2m Not processed 1.0000 FAILED - Not enough data points in dependent variable 'IMPC_HEM_030_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Knstrntm1b(KOMP)Wtsi ICS Gross Pathology and Tissue Collection / Seminal vesicle HOM f:m Supplied as data Success
Knstrntm1b(KOMP)Wtsi ICS Gross Pathology and Tissue Collection / Seminal vesicle HOM f:m Supplied as data Success
Knstrntm1b(KOMP)Wtsi ICS Gross Pathology and Tissue Collection / Seminal vesicle HOM f:m Supplied as data Success
Knstrntm1b(KOMP)Wtsi ICS Gross Pathology and Tissue Collection / Seminal vesicle HOM f:m Supplied as data Success
Knstrntm1b(KOMP)Wtsi ICS X-ray / Humerus HOM 10f:7m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Knstrntm1b(KOMP)Wtsi ICS Combined SHIRPA and Dysmorphology / Skin color - back paws HOM 12f:8m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Knstrntm1b(KOMP)Wtsi ICS Gross Pathology and Tissue Collection / Large intestine HOM f:m Supplied as data Success
Knstrntm1b(KOMP)Wtsi ICS Gross Pathology and Tissue Collection / Large intestine HOM f:m Supplied as data Success
Knstrntm1b(KOMP)Wtsi ICS Gross Pathology and Tissue Collection / Large intestine HOM f:m Supplied as data Success
Knstrntm1b(KOMP)Wtsi ICS Gross Pathology and Tissue Collection / Large intestine HOM f:m Supplied as data Success
Knstrntm1b(KOMP)Wtsi ICS Combined SHIRPA and Dysmorphology / Limb grasp HOM 12f:8m Fisher Exact Test framework 1.0000 Success
Knstrntm1b(KOMP)Wtsi ICS Combined SHIRPA and Dysmorphology / Skin color - whole body HOM 12f:8m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Knstrntm1b(KOMP)Wtsi ICS Combined SHIRPA and Dysmorphology / Coat - hair distribution - abdomen HOM 12f:8m Fisher Exact Test framework 1.0000 Success
Knstrntm1b(KOMP)Wtsi ICS X-ray / Number of digits HOM 5f:2m Not processed 1.0000 FAILED - No variability in dependent variable 'IMPC_XRY_028_001'.
Knstrntm1b(KOMP)Wtsi ICS Clinical Chemistry / Urea (Blood Urea Nitrogen - BUN) HOM 6f:4m Mixed Model framework, generalized least squares, equation withoutWeight 0.17362 Success
Knstrntm1b(KOMP)Wtsi ICS Clinical Chemistry / Urea (Blood Urea Nitrogen - BUN) HOM 5f:2m Not processed 1.0000 FAILED - Not enough data points in dependent variable 'IMPC_CBC_004_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Knstrntm1b(KOMP)Wtsi ICS Combined SHIRPA and Dysmorphology / Coat - color pattern - head HOM 12f:8m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Knstrntm1b(KOMP)Wtsi ICS Open Field / Periphery resting time HOM 12f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.79092 Success
Knstrntm1b(KOMP)Wtsi ICS Combined SHIRPA and Dysmorphology / Genitalia - presence HOM 12f:8m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Knstrntm1b(KOMP)Wtsi ICS Eye Morphology / Left outer nuclear layer HOM 11f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.43116 Success
Knstrntm1b(KOMP)Wtsi ICS X-ray / Number of lumbar vertebrae HOM 10f:7m Not processed 1.0000 FAILED - No variability in dependent variable 'IMPC_XRY_015_001'.
Knstrntm1b(KOMP)Wtsi ICS Combined SHIRPA and Dysmorphology / Hindlimb nail - shape HOM 5f:2m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Knstrntm1b(KOMP)Wtsi ICS X-ray / Ulna HOM 10f:7m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Knstrntm1b(KOMP)Wtsi ICS Combined SHIRPA and Dysmorphology / Coat - hair distribution - head HOM 12f:8m Fisher Exact Test framework 1.0000 Success
Knstrntm1b(KOMP)Wtsi ICS Gross Pathology and Tissue Collection / Uterus HOM f:m Supplied as data Success
Knstrntm1b(KOMP)Wtsi ICS Gross Pathology and Tissue Collection / Uterus HOM f:m Supplied as data Success
Knstrntm1b(KOMP)Wtsi ICS Gross Pathology and Tissue Collection / Uterus HOM f:m Supplied as data Success
Knstrntm1b(KOMP)Wtsi ICS Gross Pathology and Tissue Collection / Uterus HOM f:m Supplied as data Success
Knstrntm1b(KOMP)Wtsi ICS Eye Morphology / Corneal Sclerization HOM 4f:1m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Knstrntm1b(KOMP)Wtsi ICS Combined SHIRPA and Dysmorphology / Hindlimb digit - number HOM 7f:6m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Knstrntm1b(KOMP)Wtsi ICS Combined SHIRPA and Dysmorphology / Hindlimb digit - number HOM 5f:2m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Knstrntm1b(KOMP)Wtsi ICS Clinical Chemistry / Alkaline phosphatase HOM 5f:2m Not processed 1.0000 FAILED - Not enough data points in dependent variable 'IMPC_CBC_014_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Knstrntm1b(KOMP)Wtsi ICS Combined SHIRPA and Dysmorphology / Tail - length HOM 12f:8m Fisher Exact Test framework 1.0000 Success
Knstrntm1b(KOMP)Wtsi ICS Eye Morphology / Eye Hemorrhage or Blood Presence HOM 4f:1m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Knstrntm1b(KOMP)Wtsi ICS Hematology / Monocyte cell count HOM 4f:2m Not processed 1.0000 FAILED - Not enough data points in dependent variable 'IMPC_HEM_034_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Knstrntm1b(KOMP)Wtsi ICS Combined SHIRPA and Dysmorphology / Hindlimb nail - shape HOM 7f:6m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Knstrntm1b(KOMP)Wtsi ICS Open Field / Number of rears - total HOM 12f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.23764 Success
Knstrntm1b(KOMP)Wtsi ICS Combined SHIRPA and Dysmorphology / Unexpected behaviors HOM 12f:8m Fisher Exact Test framework 1.0000 Success
Knstrntm1b(KOMP)Wtsi ICS X-ray / Teeth HOM 10f:7m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Knstrntm1b(KOMP)Wtsi ICS Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - Global HOM 7f:6m Mixed Model framework, generalized least squares, equation withoutWeight 0.82891 Success
Knstrntm1b(KOMP)Wtsi ICS Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - Global HOM 5f:2m Not processed 1.0000 FAILED - Not enough data points in dependent variable 'IMPC_ACS_037_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Knstrntm1b(KOMP)Wtsi ICS X-ray / Number of ribs left HOM 10f:7m Not processed 1.0000 FAILED - No variability in dependent variable 'IMPC_XRY_009_001'.
Knstrntm1b(KOMP)Wtsi ICS Combined SHIRPA and Dysmorphology / Hindlimbs - size HOM 12f:8m Fisher Exact Test framework 1.0000 Success
Knstrntm1b(KOMP)Wtsi ICS Rotarod / Latency to fall mean HOM 12f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.25757 Success
Knstrntm1b(KOMP)Wtsi ICS Combined SHIRPA and Dysmorphology / Skin texture - front paws HOM 12f:8m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Knstrntm1b(KOMP)Wtsi ICS Body Composition (DEXA lean/fat) / Bone Area HOM 5f:2m Not processed 1.0000 FAILED - Not enough data points in dependent variable 'IMPC_DXA_010_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Knstrntm1b(KOMP)Wtsi ICS Body Composition (DEXA lean/fat) / Bone Area HOM 7f:3m Not processed 1.0000 FAILED - Not enough data points in dependent variable 'IMPC_DXA_010_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Knstrntm1b(KOMP)Wtsi ICS Eye Morphology / Fusion between cornea and lens HOM 3f:1m - 1.0000 FAILED - Not enough mutant measurements (3f/1m)
Knstrntm1b(KOMP)Wtsi ICS Combined SHIRPA and Dysmorphology / Coat - color - head HOM 12f:8m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Knstrntm1b(KOMP)Wtsi ICS Hematology / Mean corpuscular hemoglobin HOM 9f:6m Mixed Model framework, linear mixed-effects model, equation withoutWeight 5.1158E-31 Success
Knstrntm1b(KOMP)Wtsi ICS Echo / LVIDs HOM 7f:6m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.51862 Success
Knstrntm1b(KOMP)Wtsi ICS Echo / LVIDs HOM 5f:2m Not processed 1.0000 FAILED - Not enough data points in dependent variable 'IMPC_ECH_011_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Knstrntm1b(KOMP)Wtsi ICS Gross Pathology and Tissue Collection / Stomach HOM f:m Supplied as data Success
Knstrntm1b(KOMP)Wtsi ICS Gross Pathology and Tissue Collection / Stomach HOM f:m Supplied as data Success
Knstrntm1b(KOMP)Wtsi ICS Gross Pathology and Tissue Collection / Stomach HOM f:m Supplied as data Success
Knstrntm1b(KOMP)Wtsi ICS Gross Pathology and Tissue Collection / Stomach HOM f:m Supplied as data Success
Knstrntm1b(KOMP)Wtsi ICS Eye Morphology / Right outer nuclear layer HOM 11f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.86417 Success
Knstrntm1b(KOMP)Wtsi ICS Combined SHIRPA and Dysmorphology / Hindlimb digit - shape HOM 5f:2m Fisher Exact Test framework 1.0000 Success
Knstrntm1b(KOMP)Wtsi ICS Combined SHIRPA and Dysmorphology / Hindlimb digit - shape HOM 7f:6m Fisher Exact Test framework 1.0000 Success
Knstrntm1b(KOMP)Wtsi ICS Intraperitoneal glucose tolerance test (IPGTT) / Fasted blood glucose concentration HOM 12f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.046178 Success
Knstrntm1b(KOMP)Wtsi ICS Combined SHIRPA and Dysmorphology / Forepaw - size HOM 5f:2m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Knstrntm1b(KOMP)Wtsi ICS Hematology / Large Unstained Cell (LUC) differential count HOM 4f:2m Not processed 1.0000 FAILED - Not enough data points in dependent variable 'IMPC_HEM_040_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Knstrntm1b(KOMP)Wtsi ICS Gross Pathology and Tissue Collection / Heart HOM f:m Supplied as data Success
Knstrntm1b(KOMP)Wtsi ICS Gross Pathology and Tissue Collection / Heart HOM f:m Supplied as data Success
Knstrntm1b(KOMP)Wtsi ICS Gross Pathology and Tissue Collection / Heart HOM f:m Supplied as data Success
Knstrntm1b(KOMP)Wtsi ICS Gross Pathology and Tissue Collection / Heart HOM f:m Supplied as data Success
Knstrntm1b(KOMP)Wtsi ICS Clinical Chemistry / Total bilirubin HOM 6f:4m Mixed Model framework, generalized least squares, equation withoutWeight 0.48221 Success
Knstrntm1b(KOMP)Wtsi ICS Clinical Chemistry / Total bilirubin HOM 5f:2m Not processed 1.0000 FAILED - Not enough data points in dependent variable 'IMPC_CBC_008_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Knstrntm1b(KOMP)Wtsi ICS Combined SHIRPA and Dysmorphology / Forelimbs - position HOM 12f:8m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Knstrntm1b(KOMP)Wtsi ICS Combined SHIRPA and Dysmorphology / Forepaw - size HOM 7f:6m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Knstrntm1b(KOMP)Wtsi ICS X-ray / Fusion of ribs HOM 10f:7m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Knstrntm1b(KOMP)Wtsi ICS Body Composition (DEXA lean/fat) / BMC/Body weight HOM 5f:2m Not processed 1.0000 FAILED - Not enough data points in dependent variable 'IMPC_DXA_007_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Knstrntm1b(KOMP)Wtsi ICS Body Composition (DEXA lean/fat) / BMC/Body weight HOM 7f:3m Not processed 1.0000 FAILED - Not enough data points in dependent variable 'IMPC_DXA_007_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Knstrntm1b(KOMP)Wtsi ICS Gross Pathology and Tissue Collection / Trachea HOM f:m Supplied as data Success
Knstrntm1b(KOMP)Wtsi ICS Gross Pathology and Tissue Collection / Trachea HOM f:m Supplied as data Success
Knstrntm1b(KOMP)Wtsi ICS Gross Pathology and Tissue Collection / Trachea HOM f:m Supplied as data Success
Knstrntm1b(KOMP)Wtsi ICS Gross Pathology and Tissue Collection / Trachea HOM f:m Supplied as data Success
Knstrntm1b(KOMP)Wtsi ICS Combined SHIRPA and Dysmorphology / Lower lip morphology HOM 12f:8m Fisher Exact Test framework 1.0000 Success
Knstrntm1b(KOMP)Wtsi ICS Combined SHIRPA and Dysmorphology / Skin color - front paws HOM 12f:8m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Knstrntm1b(KOMP)Wtsi ICS Hematology / Basophil differential count HOM 4f:2m Not processed 1.0000 FAILED - Insufficient variability in dependent variable 'IMPC_HEM_038_001' for MM/TF framework. Fisher Exact Test can be better way to do the analysis.
Knstrntm1b(KOMP)Wtsi ICS Gross Pathology and Tissue Collection / Testes HOM f:m Supplied as data Success
Knstrntm1b(KOMP)Wtsi ICS Gross Pathology and Tissue Collection / Testes HOM f:m Supplied as data Success
Knstrntm1b(KOMP)Wtsi ICS Gross Pathology and Tissue Collection / Testes HOM f:m Supplied as data Success
Knstrntm1b(KOMP)Wtsi ICS Gross Pathology and Tissue Collection / Testes HOM f:m Supplied as data Success
Knstrntm1b(KOMP)Wtsi ICS Combined SHIRPA and Dysmorphology / Coat - hair texture / appearance - abdomen HOM 12f:8m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Knstrntm1b(KOMP)Wtsi ICS Gross Pathology and Tissue Collection / Urinary bladder HOM f:m Supplied as data Success
Knstrntm1b(KOMP)Wtsi ICS Gross Pathology and Tissue Collection / Urinary bladder HOM f:m Supplied as data Success
Knstrntm1b(KOMP)Wtsi ICS Gross Pathology and Tissue Collection / Urinary bladder HOM f:m Supplied as data Success
Knstrntm1b(KOMP)Wtsi ICS Gross Pathology and Tissue Collection / Urinary bladder HOM f:m Supplied as data Success
Knstrntm1b(KOMP)Wtsi ICS Open Field / Center resting time HOM 12f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.12775 Success
Knstrntm1b(KOMP)Wtsi ICS Clinical Chemistry / Glucose HOM 6f:4m Mixed Model framework, generalized least squares, equation withoutWeight 0.10837 Success
Knstrntm1b(KOMP)Wtsi ICS Clinical Chemistry / Glucose HOM 5f:2m Not processed 1.0000 FAILED - Not enough data points in dependent variable 'IMPC_CBC_018_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Knstrntm1b(KOMP)Wtsi ICS Eye Morphology / Retinal Blood Vessels Structure HOM 11f:7m Fisher Exact Test framework 1.0000 Success
Knstrntm1b(KOMP)Wtsi ICS Fertility of Homozygous Knock-out Mice / Gross Findings Female HOM f:m Supplied as data Success
Knstrntm1b(KOMP)Wtsi ICS Eye Morphology / Left total retinal thickness HOM 11f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.063165 Success
Knstrntm1b(KOMP)Wtsi ICS X-ray / Joints HOM 10f:7m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Knstrntm1b(KOMP)Wtsi ICS Eye Morphology / Corneal ulcer HOM 4f:1m Fisher Exact Test framework 0.025849 Success
Knstrntm1b(KOMP)Wtsi ICS X-ray / Skull shape HOM 10f:7m Fisher Exact Test framework 1.0000 Success
Knstrntm1b(KOMP)Wtsi ICS Echo / Fractional Shortening HOM 7f:6m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.82538 Success
Knstrntm1b(KOMP)Wtsi ICS Echo / Fractional Shortening HOM 5f:2m Not processed 1.0000 FAILED - Not enough data points in dependent variable 'IMPC_ECH_005_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Knstrntm1b(KOMP)Wtsi ICS Combined SHIRPA and Dysmorphology / Forelimb nail - number HOM 5f:2m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Knstrntm1b(KOMP)Wtsi ICS Combined SHIRPA and Dysmorphology / Forelimb nail - number HOM 7f:6m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Knstrntm1b(KOMP)Wtsi ICS Gross Pathology and Tissue Collection / Kidney HOM f:m Supplied as data Success
Knstrntm1b(KOMP)Wtsi ICS Gross Pathology and Tissue Collection / Kidney HOM f:m Supplied as data Success
Knstrntm1b(KOMP)Wtsi ICS Gross Pathology and Tissue Collection / Kidney HOM f:m Supplied as data Success
Knstrntm1b(KOMP)Wtsi ICS Gross Pathology and Tissue Collection / Kidney HOM f:m Supplied as data Success
Knstrntm1b(KOMP)Wtsi ICS Combined SHIRPA and Dysmorphology / Gait HOM 12f:8m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Knstrntm1b(KOMP)Wtsi ICS Electrocardiogram (ECG) / QRS HOM 7f:6m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.80030 Success
Knstrntm1b(KOMP)Wtsi ICS Electrocardiogram (ECG) / QRS HOM 5f:2m Not processed 1.0000 FAILED - Not enough data points in dependent variable 'IMPC_ECG_007_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Knstrntm1b(KOMP)Wtsi ICS Combined SHIRPA and Dysmorphology / Ears HOM 12f:8m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Knstrntm1b(KOMP)Wtsi ICS Gross Pathology and Tissue Collection / Small intestine HOM f:m Supplied as data Success
Knstrntm1b(KOMP)Wtsi ICS Gross Pathology and Tissue Collection / Small intestine HOM f:m Supplied as data Success
Knstrntm1b(KOMP)Wtsi ICS Gross Pathology and Tissue Collection / Small intestine HOM f:m Supplied as data Success
Knstrntm1b(KOMP)Wtsi ICS Gross Pathology and Tissue Collection / Small intestine HOM f:m Supplied as data Success
Knstrntm1b(KOMP)Wtsi ICS Combined SHIRPA and Dysmorphology / Forelimb digit - number HOM 5f:2m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Knstrntm1b(KOMP)Wtsi ICS Combined SHIRPA and Dysmorphology / Tail - presence HOM 12f:8m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Knstrntm1b(KOMP)Wtsi ICS Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI4 HOM 7f:6m Mixed Model framework, generalized least squares, equation withoutWeight 0.77657 Success
Knstrntm1b(KOMP)Wtsi ICS Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI4 HOM 5f:2m Not processed 1.0000 FAILED - Not enough data points in dependent variable 'IMPC_ACS_036_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Knstrntm1b(KOMP)Wtsi ICS X-ray / Tibia length HOM 10f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.48758 Success
Knstrntm1b(KOMP)Wtsi ICS Body Composition (DEXA lean/fat) / Lean mass HOM 7f:3m Not processed 1.0000 FAILED - Not enough data points in dependent variable 'IMPC_DXA_003_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Knstrntm1b(KOMP)Wtsi ICS Body Composition (DEXA lean/fat) / Lean mass HOM 5f:2m Not processed 1.0000 FAILED - Not enough data points in dependent variable 'IMPC_DXA_003_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Knstrntm1b(KOMP)Wtsi ICS Eye Morphology / Pupil Light Response HOM 4f:1m Fisher Exact Test framework 1.0000 Success
Knstrntm1b(KOMP)Wtsi ICS Eye Morphology / Corneal opacity HOM 5f:1m Fisher Exact Test framework 0.022916 Success
Knstrntm1b(KOMP)Wtsi ICS Open Field / Whole arena average speed HOM 12f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.13611 Success
Knstrntm1b(KOMP)Wtsi ICS X-ray / Number of pelvic vertebrae HOM 10f:7m Not processed 1.0000 FAILED - No variability in dependent variable 'IMPC_XRY_016_001'.
Knstrntm1b(KOMP)Wtsi ICS Gross Pathology and Tissue Collection / Ovary HOM f:m Supplied as data Success
Knstrntm1b(KOMP)Wtsi ICS Gross Pathology and Tissue Collection / Ovary HOM f:m Supplied as data Success
Knstrntm1b(KOMP)Wtsi ICS Gross Pathology and Tissue Collection / Ovary HOM f:m Supplied as data Success
Knstrntm1b(KOMP)Wtsi ICS Gross Pathology and Tissue Collection / Ovary HOM f:m Supplied as data Success
Knstrntm1b(KOMP)Wtsi ICS Combined SHIRPA and Dysmorphology / Forelimb digit - number HOM 7f:6m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Knstrntm1b(KOMP)Wtsi ICS Hematology / White blood cell count HOM 9f:6m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.043732 Success
Knstrntm1b(KOMP)Wtsi ICS Combined SHIRPA and Dysmorphology / Skin color - tail HOM 12f:8m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Knstrntm1b(KOMP)Wtsi ICS Gross Pathology and Tissue Collection / Eye with optic nerve HOM f:m Supplied as data Success
Knstrntm1b(KOMP)Wtsi ICS Gross Pathology and Tissue Collection / Eye with optic nerve HOM f:m Supplied as data Success
Knstrntm1b(KOMP)Wtsi ICS Gross Pathology and Tissue Collection / Eye with optic nerve HOM f:m Supplied as data Success
Knstrntm1b(KOMP)Wtsi ICS Gross Pathology and Tissue Collection / Eye with optic nerve HOM f:m Supplied as data Success

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