Dnmt3atm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Gait (inc. ataxia)
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Dnmt3atm1b(KOMP)Wtsi
|
JAX
|
Hole-board Exploration / Holepoke sequence
|
HET
|
300f:324m
|
|
|
NotProcessed |
Dnmt3atm1b(KOMP)Wtsi
|
JAX
|
Combined SHIRPA and Dysmorphology / Head bobbing
|
HET
|
8f:10m
|
|
|
NotProcessed |
Dnmt3atm1b(KOMP)Wtsi
|
JAX
|
Light-Dark Test / Percent time in light
|
HET
|
8f:10m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0332
|
Successful |
Dnmt3atm1b(KOMP)Wtsi
|
JAX
|
Combined SHIRPA and Dysmorphology / Trunk curl
|
HET
|
8f:10m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Dnmt3atm1b(KOMP)Wtsi
|
JAX
|
Open Field - centre start / Center permanence time
|
HET
|
8f:11m
|
Linear Mixed Model framework, LME, not including Weight
|
0.477
|
Successful |
Dnmt3atm1b(KOMP)Wtsi
|
JAX
|
Sleep Wake / Dark sleep bout lengths mean
|
HET
|
8f:9m
|
Linear Mixed Model framework, LME, including Weight
|
0.00329
|
Successful |
Dnmt3atm1b(KOMP)Wtsi
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP2
|
HET
|
f:2m
|
|
|
NotProcessed |
Dnmt3atm1b(KOMP)Wtsi
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP2
|
HET
|
f:7m
|
|
|
NotProcessed |
Dnmt3atm1b(KOMP)Wtsi
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP2
|
HET
|
8f:1m
|
|
|
NotProcessed |
Dnmt3atm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Convulsions
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Dnmt3atm1b(KOMP)Wtsi
|
JAX
|
Light-Dark Test / Light side time spent
|
HET
|
8f:10m
|
Linear Mixed Model framework, LME, not including Weight
|
0.847
|
Successful |
Dnmt3atm1b(KOMP)Wtsi
|
JAX
|
Gross Morphology Embryo E12.5 / Forebrain morphology
|
HET
|
21f:m
|
Supplied as data
|
1.00
|
Successful |
Dnmt3atm1b(KOMP)Wtsi
|
JAX
|
Gross Morphology Embryo E12.5 / Forebrain morphology
|
HOM
|
8f:m
|
Supplied as data
|
1.00
|
Successful |
Dnmt3atm1a(KOMP)Wtsi
|
WTSI
|
Indirect Calorimetry / Total food intake
|
HOM
|
f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.0372
|
Successful |
Dnmt3atm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Trunk curl
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Dnmt3atm1b(KOMP)Wtsi
|
JAX
|
Combined SHIRPA and Dysmorphology / Aggression
|
HET
|
8f:10m
|
Fisher Exact Test framework
|
0.0955
|
Successful |
Dnmt3atm1b(KOMP)Wtsi
|
JAX
|
Open Field - centre start / Number of Rears
|
HET
|
32f:44m
|
|
|
NotProcessed |
Dnmt3atm1a(KOMP)Wtsi
|
WTSI
|
Grip Strength / Forelimb grip strength measurement mean
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.0866
|
Successful |
Dnmt3atm1b(KOMP)Wtsi
|
JAX
|
Grip Strength / Forelimb grip strength measurement mean
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.0900
|
Successful |
Dnmt3atm1b(KOMP)Wtsi
|
JAX
|
Grip Strength / Forelimb grip strength measurement mean
|
HET
|
f:10m
|
Linear Mixed Model framework, LME, including Weight
|
0.459
|
Successful |
Dnmt3atm1b(KOMP)Wtsi
|
JAX
|
Combined SHIRPA and Dysmorphology / Startle response
|
HET
|
8f:10m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Dnmt3atm1b(KOMP)Wtsi
|
JAX
|
Open Field - centre start / Percentage center time
|
HET
|
8f:11m
|
Linear Mixed Model framework, LME, not including Weight
|
0.477
|
Successful |
Dnmt3atm1b(KOMP)Wtsi
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - BN
|
HET
|
f:2m
|
|
|
NotProcessed |
Dnmt3atm1b(KOMP)Wtsi
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - BN
|
HET
|
8f:1m
|
|
|
NotProcessed |
Dnmt3atm1b(KOMP)Wtsi
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - BN
|
HET
|
f:7m
|
|
|
NotProcessed |
Dnmt3atm1b(KOMP)Wtsi
|
JAX
|
Sleep Wake / Sleep daily percent
|
HET
|
8f:9m
|
Linear Mixed Model framework, LME, not including Weight
|
0.00517
|
Successful |
Dnmt3atm1b(KOMP)Wtsi
|
JAX
|
Light-Dark Test / Dark side time spent
|
HET
|
8f:10m
|
Linear Mixed Model framework, LME, not including Weight
|
0.847
|
Successful |
Dnmt3atm1b(KOMP)Wtsi
|
JAX
|
Sleep Wake / Sleep light phase percent
|
HET
|
8f:9m
|
Linear Mixed Model framework, LME, including Weight
|
0.366
|
Successful |
Dnmt3atm1b(KOMP)Wtsi
|
JAX
|
Open Field - centre start / Number of rears - total
|
HET
|
8f:11m
|
Linear Mixed Model framework, LME, including Weight
|
0.0247
|
Successful |
Dnmt3atm1a(KOMP)Wtsi
|
WTSI
|
Grip Strength / Forelimb grip strength measurement
|
HOM
|
21f:21m
|
|
|
NotProcessed |
Dnmt3atm1b(KOMP)Wtsi
|
JAX
|
Grip Strength / Forelimb grip strength measurement
|
HET
|
f:30m
|
|
|
NotProcessed |
Dnmt3atm1b(KOMP)Wtsi
|
JAX
|
Grip Strength / Forelimb grip strength measurement
|
HET
|
24f:24m
|
|
|
NotProcessed |
Dnmt3atm1b(KOMP)Wtsi
|
JAX
|
Tail Suspension / Latency to immobility
|
HET
|
8f:10m
|
Linear Mixed Model framework, LME, including Weight
|
0.456
|
Successful |
Dnmt3atm1b(KOMP)Wtsi
|
JAX
|
Combined SHIRPA and Dysmorphology / Locomotor activity
|
HET
|
8f:10m
|
Linear Mixed Model framework, LME, not including Weight
|
0.324
|
Successful |
Dnmt3atm1b(KOMP)Wtsi
|
JAX
|
Combined SHIRPA and Dysmorphology / Tail elevation
|
HET
|
8f:10m
|
|
|
NotProcessed |
Dnmt3atm1b(KOMP)Wtsi
|
JAX
|
Open Field - centre start / Periphery average speed
|
HET
|
8f:11m
|
Linear Mixed Model framework, LME, including Weight
|
0.446
|
Successful |
Dnmt3atm1b(KOMP)Wtsi
|
JAX
|
Light-Dark Test / Fecal boli
|
HET
|
8f:10m
|
Linear Mixed Model framework, LME, including Weight
|
0.533
|
Successful |
Dnmt3atm1b(KOMP)Wtsi
|
JAX
|
Combined SHIRPA and Dysmorphology / Contact righting
|
HET
|
8f:10m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Dnmt3atm1a(KOMP)Wtsi
|
WTSI
|
Grip Strength / Forelimb and hindlimb grip strength normalised against body weight
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
1.01×10-11
|
Successful |
Dnmt3atm1b(KOMP)Wtsi
|
JAX
|
Grip Strength / Forelimb and hindlimb grip strength normalised against body weight
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0750
|
Successful |
Dnmt3atm1b(KOMP)Wtsi
|
JAX
|
Grip Strength / Forelimb and hindlimb grip strength normalised against body weight
|
HET
|
f:10m
|
Linear Mixed Model framework, LME, not including Weight
|
0.942
|
Successful |
Dnmt3atm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Positional passivity
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Dnmt3atm1a(KOMP)Wtsi
|
WTSI
|
Indirect Calorimetry / Ambulatory activity (no. of beam cuts)
|
HOM
|
f:157m
|
|
|
NotProcessed |
Dnmt3atm1b(KOMP)Wtsi
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP1_S
|
HET
|
f:2m
|
|
|
NotProcessed |
Dnmt3atm1b(KOMP)Wtsi
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP1_S
|
HET
|
f:7m
|
|
|
NotProcessed |
Dnmt3atm1b(KOMP)Wtsi
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP1_S
|
HET
|
8f:1m
|
|
|
NotProcessed |
Dnmt3atm1b(KOMP)Wtsi
|
JAX
|
Sleep Wake / Breath rate during sleep mean
|
HET
|
8f:9m
|
Linear Mixed Model framework, LME, including Weight
|
0.483
|
Successful |
Dnmt3atm1b(KOMP)Wtsi
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI1
|
HET
|
f:2m
|
|
|
NotProcessed |
Dnmt3atm1b(KOMP)Wtsi
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI1
|
HET
|
f:7m
|
Linear Model Using Generalized Least Squares framework, GLS, including Weight
|
0.307
|
Successful |
Dnmt3atm1b(KOMP)Wtsi
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI1
|
HET
|
8f:1m
|
Linear Mixed Model framework, LME, including Weight
|
0.542
|
Successful |
Dnmt3atm1b(KOMP)Wtsi
|
JAX
|
Rotarod / Learning slope
|
HET
|
8f:10m
|
Linear Mixed Model framework, LME, not including Weight
|
0.557
|
Successful |
Dnmt3atm1b(KOMP)Wtsi
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP4
|
HET
|
f:7m
|
|
|
NotProcessed |
Dnmt3atm1b(KOMP)Wtsi
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI3
|
HET
|
f:2m
|
|
|
NotProcessed |
Dnmt3atm1b(KOMP)Wtsi
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI3
|
HET
|
f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.00893
|
Successful |
Dnmt3atm1b(KOMP)Wtsi
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI3
|
HET
|
8f:1m
|
Linear Mixed Model framework, LME, not including Weight
|
0.414
|
Successful |
Dnmt3atm1b(KOMP)Wtsi
|
JAX
|
Sleep Wake / Sleep bout lengths mean
|
HET
|
8f:9m
|
Linear Mixed Model framework, LME, including Weight
|
0.0927
|
Successful |
Dnmt3atm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Startle response
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Dnmt3atm1b(KOMP)Wtsi
|
JAX
|
Combined SHIRPA and Dysmorphology / Tremor
|
HET
|
8f:10m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Dnmt3atm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Pinna touch reflex
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Dnmt3atm1a(KOMP)Wtsi
|
WTSI
|
Indirect Calorimetry / Total water intake
|
HOM
|
f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.849
|
Successful |
Dnmt3atm1b(KOMP)Wtsi
|
JAX
|
Combined SHIRPA and Dysmorphology / Limb grasp
|
HET
|
8f:10m
|
Fisher Exact Test framework
|
0.403
|
Successful |
Dnmt3atm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Head bobbing/circling
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Dnmt3atm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Tail elevation
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Dnmt3atm1b(KOMP)Wtsi
|
JAX
|
Sleep Wake / Light sleep bout lengths mean
|
HET
|
8f:9m
|
Linear Mixed Model framework, LME, not including Weight
|
0.176
|
Successful |
Dnmt3atm1b(KOMP)Wtsi
|
JAX
|
Light-Dark Test / Percent time in dark
|
HET
|
8f:10m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0332
|
Successful |
Dnmt3atm1b(KOMP)Wtsi
|
JAX
|
Rotarod / Average duration
|
HET
|
8f:10m
|
Linear Mixed Model framework, LME, including Weight
|
0.0414
|
Successful |
Dnmt3atm1b(KOMP)Wtsi
|
JAX
|
Sleep Wake / Activity onset with respect to dark onset median
|
HET
|
8f:1m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.213
|
Successful |
Dnmt3atm1b(KOMP)Wtsi
|
JAX
|
Electroconvulsive Threshold Testing / mA threshold inducing clonic seizure
|
HET
|
f:3m
|
|
|
NotProcessed |
Dnmt3atm1b(KOMP)Wtsi
|
JAX
|
Electroconvulsive Threshold Testing / mA threshold inducing clonic seizure
|
HET
|
8f:5m
|
Linear Mixed Model framework, LME, not including Weight
|
1.49×10-12
|
Successful |
Dnmt3atm1b(KOMP)Wtsi
|
JAX
|
Open Field - centre start / Whole arena average speed
|
HET
|
8f:11m
|
Linear Mixed Model framework, LME, not including Weight
|
0.412
|
Successful |
Dnmt3atm1b(KOMP)Wtsi
|
JAX
|
Sleep Wake / Light sleep bout lengths standard deviation
|
HET
|
8f:9m
|
Linear Mixed Model framework, LME, including Weight
|
0.912
|
Successful |
Dnmt3atm1b(KOMP)Wtsi
|
JAX
|
Combined SHIRPA and Dysmorphology / Activity (body position)
|
HET
|
8f:10m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Dnmt3atm1b(KOMP)Wtsi
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP1
|
HET
|
f:2m
|
|
|
NotProcessed |
Dnmt3atm1b(KOMP)Wtsi
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP1
|
HET
|
f:7m
|
|
|
NotProcessed |
Dnmt3atm1b(KOMP)Wtsi
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP1
|
HET
|
8f:1m
|
|
|
NotProcessed |
Dnmt3atm1b(KOMP)Wtsi
|
JAX
|
Open Field - centre start / Center average speed
|
HET
|
8f:11m
|
Linear Mixed Model framework, LME, including Weight
|
0.564
|
Successful |
Dnmt3atm1b(KOMP)Wtsi
|
JAX
|
Light-Dark Test / Side changes
|
HET
|
8f:10m
|
Linear Mixed Model framework, LME, including Weight
|
0.525
|
Successful |
Dnmt3atm1b(KOMP)Wtsi
|
JAX
|
Gross Morphology Embryo E12.5 / Midbrain morphology
|
HOM
|
8f:m
|
Supplied as data
|
1.00
|
Successful |
Dnmt3atm1b(KOMP)Wtsi
|
JAX
|
Gross Morphology Embryo E12.5 / Midbrain morphology
|
HET
|
21f:m
|
Supplied as data
|
1.00
|
Successful |
Dnmt3atm1a(KOMP)Wtsi
|
WTSI
|
Indirect Calorimetry / Cumulative food intake
|
HOM
|
f:157m
|
|
|
NotProcessed |
Dnmt3atm1b(KOMP)Wtsi
|
JAX
|
Hole-board Exploration / Total holepokes
|
HET
|
8f:10m
|
Linear Mixed Model framework, LME, including Weight
|
0.313
|
Successful |
Dnmt3atm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Transfer arousal
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
0.186
|
Successful |
Dnmt3atm1b(KOMP)Wtsi
|
JAX
|
Combined SHIRPA and Dysmorphology / Unexpected behaviors
|
HET
|
8f:10m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Dnmt3atm1b(KOMP)Wtsi
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - Global
|
HET
|
f:2m
|
|
|
NotProcessed |
Dnmt3atm1b(KOMP)Wtsi
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - Global
|
HET
|
f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0464
|
Successful |
Dnmt3atm1b(KOMP)Wtsi
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - Global
|
HET
|
8f:1m
|
Linear Mixed Model framework, LME, not including Weight
|
0.286
|
Successful |
Dnmt3atm1b(KOMP)Wtsi
|
JAX
|
Gross Morphology Embryo E12.5 / Neural Tube Closure
|
HET
|
21f:m
|
Supplied as data
|
1.00
|
Successful |
Dnmt3atm1b(KOMP)Wtsi
|
JAX
|
Gross Morphology Embryo E12.5 / Neural Tube Closure
|
HOM
|
8f:m
|
Supplied as data
|
1.00
|
Successful |
Dnmt3atm1b(KOMP)Wtsi
|
JAX
|
Open Field - centre start / Periphery distance travelled
|
HET
|
8f:11m
|
Linear Mixed Model framework, LME, including Weight
|
0.605
|
Successful |
Dnmt3atm1b(KOMP)Wtsi
|
JAX
|
Open Field - centre start / Whole arena resting time
|
HET
|
8f:11m
|
Linear Mixed Model framework, LME, including Weight
|
0.330
|
Successful |
Dnmt3atm1b(KOMP)Wtsi
|
JAX
|
Light-Dark Test / Time mobile light side
|
HET
|
8f:10m
|
Linear Mixed Model framework, LME, including Weight
|
0.255
|
Successful |
Dnmt3atm1b(KOMP)Wtsi
|
JAX
|
Sleep Wake / Breath rate during sleep standard deviation
|
HET
|
8f:9m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0383
|
Successful |
Dnmt3atm1b(KOMP)Wtsi
|
JAX
|
Open Field - centre start / Distance travelled
|
HET
|
32f:44m
|
|
|
NotProcessed |
Dnmt3atm1a(KOMP)Wtsi
|
WTSI
|
Indirect Calorimetry / Total activity (no. of fine movement + no. of beam cuts)
|
HOM
|
f:157m
|
|
|
NotProcessed |
Dnmt3atm1b(KOMP)Wtsi
|
JAX
|
Gross Morphology Embryo E12.5 / Hindbrain morphology
|
HET
|
21f:m
|
Supplied as data
|
1.00
|
Successful |
Dnmt3atm1b(KOMP)Wtsi
|
JAX
|
Gross Morphology Embryo E12.5 / Hindbrain morphology
|
HOM
|
8f:m
|
Supplied as data
|
1.00
|
Successful |
Dnmt3atm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Limb grasping
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Dnmt3atm1b(KOMP)Wtsi
|
JAX
|
Combined SHIRPA and Dysmorphology / Vocalization
|
HET
|
8f:10m
|
Fisher Exact Test framework
|
0.623
|
Successful |
Dnmt3atm1b(KOMP)Wtsi
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP3_S
|
HET
|
f:7m
|
|
|
NotProcessed |
Dnmt3atm1b(KOMP)Wtsi
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP3_S
|
HET
|
8f:1m
|
|
|
NotProcessed |
Dnmt3atm1b(KOMP)Wtsi
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP3_S
|
HET
|
f:2m
|
|
|
NotProcessed |
Dnmt3atm1b(KOMP)Wtsi
|
JAX
|
Combined SHIRPA and Dysmorphology / Touch escape
|
HET
|
8f:10m
|
|
|
NotProcessed |
Dnmt3atm1b(KOMP)Wtsi
|
JAX
|
Tail Suspension / Time immobile
|
HET
|
8f:10m
|
Linear Mixed Model framework, LME, including Weight
|
0.0279
|
Successful |
Dnmt3atm1a(KOMP)Wtsi
|
WTSI
|
Grip Strength / Forelimb and hindlimb grip strength measurement mean
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
1.83×10-12
|
Successful |
Dnmt3atm1b(KOMP)Wtsi
|
JAX
|
Grip Strength / Forelimb and hindlimb grip strength measurement mean
|
HET
|
f:10m
|
Linear Mixed Model framework, LME, including Weight
|
0.254
|
Successful |
Dnmt3atm1b(KOMP)Wtsi
|
JAX
|
Grip Strength / Forelimb and hindlimb grip strength measurement mean
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.351
|
Successful |
Dnmt3atm1b(KOMP)Wtsi
|
JAX
|
Rotarod / Latency to fall
|
HET
|
40f:50m
|
|
|
NotProcessed |
Dnmt3atm1b(KOMP)Wtsi
|
JAX
|
Sleep Wake / Peak wake with respect to dark onset median
|
HET
|
8f:9m
|
Linear Mixed Model framework, LME, including Weight
|
0.679
|
Successful |
Dnmt3atm1b(KOMP)Wtsi
|
JAX
|
Grip Strength / Forelimb grip strength normalised against body weight
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.00667
|
Successful |
Dnmt3atm1a(KOMP)Wtsi
|
WTSI
|
Grip Strength / Forelimb grip strength normalised against body weight
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.106
|
Successful |
Dnmt3atm1b(KOMP)Wtsi
|
JAX
|
Grip Strength / Forelimb grip strength normalised against body weight
|
HET
|
f:10m
|
Linear Mixed Model framework, LME, not including Weight
|
0.173
|
Successful |
Dnmt3atm1b(KOMP)Wtsi
|
JAX
|
Eye Morphology / Optic Disc
|
HET
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Dnmt3atm1a(KOMP)Wtsi
|
WTSI
|
Eye Morphology / Optic Disc
|
HOM
|
6f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Dnmt3atm1b(KOMP)Wtsi
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP2_S
|
HET
|
f:2m
|
|
|
NotProcessed |
Dnmt3atm1b(KOMP)Wtsi
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP2_S
|
HET
|
f:7m
|
|
|
NotProcessed |
Dnmt3atm1b(KOMP)Wtsi
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP2_S
|
HET
|
8f:1m
|
|
|
NotProcessed |
Dnmt3atm1b(KOMP)Wtsi
|
JAX
|
Light-Dark Test / Time mobile dark side
|
HET
|
8f:10m
|
Linear Mixed Model framework, LME, including Weight
|
0.716
|
Successful |
Dnmt3atm1b(KOMP)Wtsi
|
JAX
|
Sleep Wake / Sleep dark phase percent
|
HET
|
8f:9m
|
Linear Mixed Model framework, LME, including Weight
|
0.00692
|
Successful |
Dnmt3atm1a(KOMP)Wtsi
|
WTSI
|
Grip Strength / Forelimb and hindlimb grip strength measurement
|
HOM
|
21f:21m
|
|
|
NotProcessed |
Dnmt3atm1b(KOMP)Wtsi
|
JAX
|
Grip Strength / Forelimb and hindlimb grip strength measurement
|
HET
|
f:30m
|
|
|
NotProcessed |
Dnmt3atm1b(KOMP)Wtsi
|
JAX
|
Grip Strength / Forelimb and hindlimb grip strength measurement
|
HET
|
24f:24m
|
|
|
NotProcessed |
Dnmt3atm1b(KOMP)Wtsi
|
JAX
|
Open Field - centre start / Distance travelled - total
|
HET
|
8f:11m
|
Linear Mixed Model framework, LME, not including Weight
|
0.411
|
Successful |
Dnmt3atm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Corneal touch reflex
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Dnmt3atm1b(KOMP)Wtsi
|
JAX
|
Open Field - centre start / Periphery permanence time
|
HET
|
8f:11m
|
Linear Mixed Model framework, LME, not including Weight
|
0.478
|
Successful |
Dnmt3atm1b(KOMP)Wtsi
|
JAX
|
Combined SHIRPA and Dysmorphology / Gait
|
HET
|
8f:10m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Dnmt3atm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Contact righting reflex
|
HOM
|
7f:7m
|
|
|
NotProcessed |
Dnmt3atm1b(KOMP)Wtsi
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI2
|
HET
|
f:2m
|
|
|
NotProcessed |
Dnmt3atm1b(KOMP)Wtsi
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI2
|
HET
|
f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.146
|
Successful |
Dnmt3atm1b(KOMP)Wtsi
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI2
|
HET
|
8f:1m
|
Linear Mixed Model framework, LME, not including Weight
|
0.395
|
Successful |
Dnmt3atm1b(KOMP)Wtsi
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - S
|
HET
|
f:2m
|
|
|
NotProcessed |
Dnmt3atm1b(KOMP)Wtsi
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - S
|
HET
|
f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0968
|
Successful |
Dnmt3atm1b(KOMP)Wtsi
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - S
|
HET
|
8f:1m
|
Linear Mixed Model framework, LME, not including Weight
|
0.341
|
Successful |
Dnmt3atm1b(KOMP)Wtsi
|
JAX
|
Light-Dark Test / Latency to first transition into dark
|
HET
|
8f:10m
|
Linear Mixed Model framework, LME, including Weight
|
0.263
|
Successful |
Dnmt3atm1b(KOMP)Wtsi
|
JAX
|
Rotarod / Learning difference
|
HET
|
8f:10m
|
Linear Mixed Model framework, LME, including Weight
|
0.912
|
Successful |
Dnmt3atm1b(KOMP)Wtsi
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI4
|
HET
|
f:2m
|
|
|
NotProcessed |
Dnmt3atm1b(KOMP)Wtsi
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI4
|
HET
|
f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0128
|
Successful |
Dnmt3atm1b(KOMP)Wtsi
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP3
|
HET
|
f:7m
|
|
|
NotProcessed |
Dnmt3atm1b(KOMP)Wtsi
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP3
|
HET
|
8f:1m
|
|
|
NotProcessed |
Dnmt3atm1b(KOMP)Wtsi
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP3
|
HET
|
f:2m
|
|
|
NotProcessed |
Dnmt3atm1b(KOMP)Wtsi
|
JAX
|
Sleep Wake / Dark sleep bout lengths standard deviation
|
HET
|
8f:9m
|
Linear Mixed Model framework, LME, not including Weight
|
0.884
|
Successful |
Dnmt3atm1a(KOMP)Wtsi
|
WTSI
|
Eye Morphology / Pupil Light Response
|
HOM
|
6f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Dnmt3atm1b(KOMP)Wtsi
|
JAX
|
Eye Morphology / Pupil Light Response
|
HET
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Dnmt3atm1b(KOMP)Wtsi
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP4_S
|
HET
|
f:2m
|
|
|
NotProcessed |
Dnmt3atm1b(KOMP)Wtsi
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP4_S
|
HET
|
f:7m
|
|
|
NotProcessed |
Dnmt3atm1b(KOMP)Wtsi
|
JAX
|
Combined SHIRPA and Dysmorphology / Transfer arousal
|
HET
|
8f:10m
|
|
|
NotProcessed |
Dnmt3atm1b(KOMP)Wtsi
|
JAX
|
Sleep Wake / Sleep bout lengths standard deviation
|
HET
|
8f:9m
|
Linear Mixed Model framework, LME, including Weight
|
0.863
|
Successful |
Dnmt3atm1a(KOMP)Wtsi
|
WTSI
|
Combined SHIRPA and Dysmorphology / Tremor
|
HOM
|
7f:7m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Dnmt3atm1b(KOMP)Wtsi
|
JAX
|
Open Field - centre start / Center distance travelled
|
HET
|
8f:11m
|
Linear Mixed Model framework, LME, including Weight
|
0.741
|
Successful |