Dnmt3atm1a(KOMP)Wtsi
|
WTSI
|
Clinical Chemistry / Free fatty acids
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.582
|
Successful |
Dnmt3atm1b(KOMP)Wtsi
|
JAX
|
Clinical Chemistry / Free fatty acids
|
HET
|
7f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.629
|
Successful |
Dnmt3atm1b(KOMP)Wtsi
|
JAX
|
Clinical Chemistry / Alanine aminotransferase
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.268
|
Successful |
Dnmt3atm1a(KOMP)Wtsi
|
WTSI
|
Clinical Chemistry / Alanine aminotransferase
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.663
|
Successful |
Dnmt3atm1a(KOMP)Wtsi
|
WTSI
|
Indirect Calorimetry / Heat production (metabolic rate)
|
HOM
|
f:157m
|
|
|
NotProcessed |
Dnmt3atm1b(KOMP)Wtsi
|
JAX
|
Clinical Chemistry / Calcium
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0416
|
Successful |
Dnmt3atm1a(KOMP)Wtsi
|
WTSI
|
Clinical Chemistry / Calcium
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.419
|
Successful |
Dnmt3atm1b(KOMP)Wtsi
|
JAX
|
Plasma Chemistry / Total cholesterol
|
HET
|
4f:m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.412
|
Successful |
Dnmt3atm1b(KOMP)Wtsi
|
JAX
|
Plasma Chemistry / Total cholesterol
|
HET
|
4f:5m
|
Linear Mixed Model framework, LME, including Weight
|
3.10×10-05
|
Successful |
Dnmt3atm1a(KOMP)Wtsi
|
WTSI
|
Clinical Chemistry / Creatinine
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.582
|
Successful |
Dnmt3atm1b(KOMP)Wtsi
|
JAX
|
Clinical Chemistry / Glucose
|
HET
|
7f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.482
|
Successful |
Dnmt3atm1a(KOMP)Wtsi
|
WTSI
|
Clinical Chemistry / Glucose
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.919
|
Successful |
Dnmt3atm1b(KOMP)Wtsi
|
JAX
|
Plasma Chemistry / Triglycerides
|
HET
|
4f:m
|
Linear Mixed Model framework, LME, including Weight
|
0.716
|
Successful |
Dnmt3atm1b(KOMP)Wtsi
|
JAX
|
Plasma Chemistry / Triglycerides
|
HET
|
4f:5m
|
Linear Mixed Model framework, LME, including Weight
|
0.838
|
Successful |
Dnmt3atm1a(KOMP)Wtsi
|
WTSI
|
Clinical Chemistry / Fructosamine
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.722
|
Successful |
Dnmt3atm1b(KOMP)Wtsi
|
JAX
|
Clinical Chemistry / Sodium
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.00936
|
Successful |
Dnmt3atm1a(KOMP)Wtsi
|
WTSI
|
Clinical Chemistry / Sodium
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.120
|
Successful |
Dnmt3atm1a(KOMP)Wtsi
|
WTSI
|
Clinical Chemistry / Alkaline phosphatase
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.213
|
Successful |
Dnmt3atm1b(KOMP)Wtsi
|
JAX
|
Clinical Chemistry / Alkaline phosphatase
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.370
|
Successful |
Dnmt3atm1a(KOMP)Wtsi
|
WTSI
|
Clinical Chemistry / Glycerol
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.0879
|
Successful |
Dnmt3atm1a(KOMP)Wtsi
|
WTSI
|
Clinical Chemistry / Alpha-amylase
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.656
|
Successful |
Dnmt3atm1b(KOMP)Wtsi
|
JAX
|
Clinical Chemistry / Iron
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.0415
|
Successful |
Dnmt3atm1a(KOMP)Wtsi
|
WTSI
|
Clinical Chemistry / Iron
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.430
|
Successful |
Dnmt3atm1a(KOMP)Wtsi
|
WTSI
|
Clinical Chemistry / Magnesium
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.940
|
Successful |
Dnmt3atm1b(KOMP)Wtsi
|
JAX
|
Intraperitoneal glucose tolerance test (IPGTT) / Area under glucose response curve
|
HET
|
8f:10m
|
Linear Mixed Model framework, LME, not including Weight
|
0.188
|
Successful |
Dnmt3atm1a(KOMP)Wtsi
|
WTSI
|
Intraperitoneal glucose tolerance test (IPGTT) / Area under glucose response curve
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.548
|
Successful |
Dnmt3atm1a(KOMP)Wtsi
|
WTSI
|
Clinical Chemistry / Creatine kinase
|
HOM
|
6f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.621
|
Successful |
Dnmt3atm1a(KOMP)Wtsi
|
WTSI
|
Clinical Chemistry / Total cholesterol
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.0181
|
Successful |
Dnmt3atm1b(KOMP)Wtsi
|
JAX
|
Clinical Chemistry / Total cholesterol
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.250
|
Successful |
Dnmt3atm1b(KOMP)Wtsi
|
JAX
|
Clinical Chemistry / Total protein
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.00697
|
Successful |
Dnmt3atm1a(KOMP)Wtsi
|
WTSI
|
Clinical Chemistry / Total protein
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.223
|
Successful |
Dnmt3atm1b(KOMP)Wtsi
|
JAX
|
Clinical Chemistry / Cholesterol ratio
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.330
|
Successful |
Dnmt3atm1b(KOMP)Wtsi
|
JAX
|
Body Composition (DEXA lean/fat) / Fat/Body weight
|
HET
|
8f:9m
|
Linear Mixed Model framework, LME, not including Weight
|
3.31×10-05
|
Successful |
Dnmt3atm1a(KOMP)Wtsi
|
WTSI
|
Body Composition (DEXA lean/fat) / Fat/Body weight
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.336
|
Successful |
Dnmt3atm1b(KOMP)Wtsi
|
JAX
|
Plasma Chemistry / HDL cholesterol
|
HET
|
4f:m
|
Linear Mixed Model framework, LME, including Weight
|
0.0246
|
Successful |
Dnmt3atm1b(KOMP)Wtsi
|
JAX
|
Plasma Chemistry / HDL cholesterol
|
HET
|
4f:5m
|
Linear Mixed Model framework, LME, including Weight
|
1.53×10-06
|
Successful |
Dnmt3atm1a(KOMP)Wtsi
|
WTSI
|
Indirect Calorimetry / Oxygen consumption
|
HOM
|
f:157m
|
|
|
NotProcessed |
Dnmt3atm1b(KOMP)Wtsi
|
JAX
|
Clinical Chemistry / Albumin
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.00102
|
Successful |
Dnmt3atm1a(KOMP)Wtsi
|
WTSI
|
Clinical Chemistry / Albumin
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.00215
|
Successful |
Dnmt3atm1b(KOMP)Wtsi
|
JAX
|
Body Composition (DEXA lean/fat) / Fat mass
|
HET
|
8f:9m
|
Linear Mixed Model framework, LME, including Weight
|
0.000410
|
Successful |
Dnmt3atm1a(KOMP)Wtsi
|
WTSI
|
Body Composition (DEXA lean/fat) / Fat mass
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.710
|
Successful |
Dnmt3atm1b(KOMP)Wtsi
|
JAX
|
Clinical Chemistry / Potassium
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.234
|
Successful |
Dnmt3atm1a(KOMP)Wtsi
|
WTSI
|
Clinical Chemistry / Potassium
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.410
|
Successful |
Dnmt3atm1b(KOMP)Wtsi
|
JAX
|
Intraperitoneal glucose tolerance test (IPGTT) / Initial response to glucose challenge
|
HET
|
8f:10m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0241
|
Successful |
Dnmt3atm1a(KOMP)Wtsi
|
WTSI
|
Intraperitoneal glucose tolerance test (IPGTT) / Initial response to glucose challenge
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.922
|
Successful |
Dnmt3atm1b(KOMP)Wtsi
|
JAX
|
Clinical Chemistry / Phosphorus
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.0563
|
Successful |
Dnmt3atm1a(KOMP)Wtsi
|
WTSI
|
Clinical Chemistry / Phosphorus
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.326
|
Successful |
Dnmt3atm1a(KOMP)Wtsi
|
WTSI
|
Clinical Chemistry / HDL-cholesterol
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.162
|
Successful |
Dnmt3atm1b(KOMP)Wtsi
|
JAX
|
Clinical Chemistry / HDL-cholesterol
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.174
|
Successful |
Dnmt3atm1a(KOMP)Wtsi
|
WTSI
|
Clinical Chemistry / Thyroxine
|
HOM
|
3f:3m
|
|
|
NotProcessed |
Dnmt3atm1b(KOMP)Wtsi
|
JAX
|
Clinical Chemistry / Chloride
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.00337
|
Successful |
Dnmt3atm1a(KOMP)Wtsi
|
WTSI
|
Clinical Chemistry / Chloride
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.793
|
Successful |
Dnmt3atm1b(KOMP)Wtsi
|
JAX
|
Insulin Blood Level / Insulin
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.0129
|
Successful |
Dnmt3atm1a(KOMP)Wtsi
|
WTSI
|
Insulin Blood Level / Insulin
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.345
|
Successful |
Dnmt3atm1b(KOMP)Wtsi
|
JAX
|
Gross Morphology Embryo E12.5 / Edema
|
HOM
|
8f:m
|
Supplied as data
|
1.00
|
Successful |
Dnmt3atm1b(KOMP)Wtsi
|
JAX
|
Gross Morphology Embryo E12.5 / Edema
|
HET
|
21f:m
|
Supplied as data
|
1.00
|
Successful |
Dnmt3atm1b(KOMP)Wtsi
|
JAX
|
Plasma Chemistry / Free fatty acids
|
HET
|
4f:5m
|
Linear Mixed Model framework, LME, not including Weight
|
0.139
|
Successful |
Dnmt3atm1b(KOMP)Wtsi
|
JAX
|
Plasma Chemistry / Free fatty acids
|
HET
|
4f:m
|
Linear Mixed Model framework, LME, not including Weight
|
0.249
|
Successful |
Dnmt3atm1b(KOMP)Wtsi
|
JAX
|
Intraperitoneal glucose tolerance test (IPGTT) / Blood glucose concentration
|
HET
|
40f:50m
|
|
|
NotProcessed |
Dnmt3atm1a(KOMP)Wtsi
|
WTSI
|
Intraperitoneal glucose tolerance test (IPGTT) / Blood glucose concentration
|
HOM
|
35f:35m
|
|
|
NotProcessed |
Dnmt3atm1b(KOMP)Wtsi
|
JAX
|
Intraperitoneal glucose tolerance test (IPGTT) / Fasted blood glucose concentration
|
HET
|
8f:10m
|
Linear Mixed Model framework, LME, not including Weight
|
0.179
|
Successful |
Dnmt3atm1a(KOMP)Wtsi
|
WTSI
|
Intraperitoneal glucose tolerance test (IPGTT) / Fasted blood glucose concentration
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, not including Weight
|
0.724
|
Successful |
Dnmt3atm1a(KOMP)Wtsi
|
WTSI
|
Clinical Chemistry / Total bilirubin
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.803
|
Successful |
Dnmt3atm1b(KOMP)Wtsi
|
JAX
|
Clinical Chemistry / Total bilirubin
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.939
|
Successful |
Dnmt3atm1b(KOMP)Wtsi
|
JAX
|
Clinical Chemistry / Aspartate aminotransferase
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.172
|
Successful |
Dnmt3atm1a(KOMP)Wtsi
|
WTSI
|
Clinical Chemistry / Aspartate aminotransferase
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.438
|
Successful |
Dnmt3atm1a(KOMP)Wtsi
|
WTSI
|
Indirect Calorimetry / Respiratory Exchange Ratio
|
HOM
|
f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.00831
|
Successful |
Dnmt3atm1a(KOMP)Wtsi
|
WTSI
|
Clinical Chemistry / LDL-cholesterol
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.0430
|
Successful |
Dnmt3atm1a(KOMP)Wtsi
|
WTSI
|
Indirect Calorimetry / Carbon dioxide production
|
HOM
|
f:157m
|
|
|
NotProcessed |
Dnmt3atm1b(KOMP)Wtsi
|
JAX
|
Plasma Chemistry / Glucose
|
HET
|
4f:m
|
Linear Mixed Model framework, LME, including Weight
|
0.121
|
Successful |
Dnmt3atm1b(KOMP)Wtsi
|
JAX
|
Plasma Chemistry / Glucose
|
HET
|
4f:5m
|
Linear Mixed Model framework, LME, including Weight
|
2.22×10-05
|
Successful |
Dnmt3atm1b(KOMP)Wtsi
|
JAX
|
Clinical Chemistry / Triglycerides
|
HET
|
7f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.189
|
Successful |
Dnmt3atm1a(KOMP)Wtsi
|
WTSI
|
Clinical Chemistry / Triglycerides
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.216
|
Successful |
Dnmt3atm1b(KOMP)Wtsi
|
JAX
|
Clinical Chemistry / Urea (Blood Urea Nitrogen - BUN)
|
HET
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.0984
|
Successful |
Dnmt3atm1a(KOMP)Wtsi
|
WTSI
|
Clinical Chemistry / Urea (Blood Urea Nitrogen - BUN)
|
HOM
|
7f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.145
|
Successful |