Mmp8tm1.1(KOMP)Vlcg
|
JAX
|
Open Field - centre start / Whole arena average speed
|
HOM
|
8f:9m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0468
|
Successful |
Mmp8tm1.1(KOMP)Vlcg
|
JAX
|
Electroconvulsive Threshold Testing / mA threshold inducing clonic seizure
|
HOM
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.326
|
Successful |
Mmp8tm1.1(KOMP)Vlcg
|
JAX
|
Hole-board Exploration / Holepoke sequence
|
HOM
|
308f:321m
|
|
|
NotProcessed |
Mmp8tm1.1(KOMP)Vlcg
|
JAX
|
Sleep Wake / Light sleep bout lengths standard deviation
|
HOM
|
8f:6m
|
Linear Mixed Model framework, LME, including Weight
|
0.962
|
Successful |
Mmp8tm1.1(KOMP)Vlcg
|
JAX
|
Combined SHIRPA and Dysmorphology / Activity (body position)
|
HOM
|
7f:9m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Mmp8tm1.1(KOMP)Vlcg
|
JAX
|
Combined SHIRPA and Dysmorphology / Head bobbing
|
HOM
|
7f:9m
|
|
|
NotProcessed |
Mmp8tm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP1
|
HOM
|
6f:4m
|
|
|
NotProcessed |
Mmp8tm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP1
|
HOM
|
2f:5m
|
|
|
NotProcessed |
Mmp8tm1.1(KOMP)Vlcg
|
JAX
|
Light-Dark Test / Percent time in light
|
HOM
|
8f:9m
|
Linear Mixed Model framework, LME, including Weight
|
0.439
|
Successful |
Mmp8tm1.1(KOMP)Vlcg
|
JAX
|
Open Field - centre start / Center average speed
|
HOM
|
8f:9m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0936
|
Successful |
Mmp8tm1.1(KOMP)Vlcg
|
JAX
|
Combined SHIRPA and Dysmorphology / Trunk curl
|
HOM
|
7f:9m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Mmp8tm1.1(KOMP)Vlcg
|
JAX
|
Open Field - centre start / Center permanence time
|
HOM
|
8f:9m
|
Linear Mixed Model framework, LME, not including Weight
|
0.217
|
Successful |
Mmp8tm1.1(KOMP)Vlcg
|
JAX
|
Light-Dark Test / Side changes
|
HOM
|
8f:9m
|
Linear Mixed Model framework, LME, including Weight
|
0.470
|
Successful |
Mmp8tm1.1(KOMP)Vlcg
|
JAX
|
Hole-board Exploration / Total holepokes
|
HOM
|
8f:9m
|
Linear Mixed Model framework, LME, including Weight
|
0.318
|
Successful |
Mmp8tm1.1(KOMP)Vlcg
|
JAX
|
Sleep Wake / Dark sleep bout lengths mean
|
HOM
|
8f:6m
|
Linear Mixed Model framework, LME, including Weight
|
0.811
|
Successful |
Mmp8tm1.1(KOMP)Vlcg
|
JAX
|
Combined SHIRPA and Dysmorphology / Unexpected behaviors
|
HOM
|
7f:9m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Mmp8tm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP2
|
HOM
|
6f:4m
|
|
|
NotProcessed |
Mmp8tm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP2
|
HOM
|
2f:5m
|
|
|
NotProcessed |
Mmp8tm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - Global
|
HOM
|
6f:4m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0303
|
Successful |
Mmp8tm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - Global
|
HOM
|
2f:5m
|
Linear Mixed Model framework, LME, not including Weight
|
0.189
|
Successful |
Mmp8tm1.1(KOMP)Vlcg
|
JAX
|
Light-Dark Test / Light side time spent
|
HOM
|
8f:9m
|
Linear Mixed Model framework, LME, not including Weight
|
0.843
|
Successful |
Mmp8tm1.1(KOMP)Vlcg
|
JAX
|
Open Field - centre start / Periphery distance travelled
|
HOM
|
8f:9m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0101
|
Successful |
Mmp8tm1.1(KOMP)Vlcg
|
JAX
|
Open Field - centre start / Whole arena resting time
|
HOM
|
8f:9m
|
Linear Mixed Model framework, LME, including Weight
|
0.0652
|
Successful |
Mmp8tm1.1(KOMP)Vlcg
|
JAX
|
Combined SHIRPA and Dysmorphology / Aggression
|
HOM
|
7f:9m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Mmp8tm1.1(KOMP)Vlcg
|
JAX
|
Open Field - centre start / Number of Rears
|
HOM
|
32f:36m
|
|
|
NotProcessed |
Mmp8tm1.1(KOMP)Vlcg
|
JAX
|
Light-Dark Test / Time mobile light side
|
HOM
|
8f:9m
|
Linear Mixed Model framework, LME, including Weight
|
0.0558
|
Successful |
Mmp8tm1.1(KOMP)Vlcg
|
JAX
|
Grip Strength / Forelimb grip strength measurement mean
|
HOM
|
8f:9m
|
Linear Mixed Model framework, LME, including Weight
|
0.874
|
Successful |
Mmp8tm1.1(KOMP)Vlcg
|
JAX
|
Combined SHIRPA and Dysmorphology / Startle response
|
HOM
|
7f:9m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Mmp8tm1.1(KOMP)Vlcg
|
JAX
|
Sleep Wake / Breath rate during sleep standard deviation
|
HOM
|
8f:6m
|
Linear Mixed Model framework, LME, not including Weight
|
0.785
|
Successful |
Mmp8tm1.1(KOMP)Vlcg
|
JAX
|
Open Field - centre start / Percentage center time
|
HOM
|
8f:9m
|
Linear Mixed Model framework, LME, not including Weight
|
0.217
|
Successful |
Mmp8tm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - BN
|
HOM
|
6f:4m
|
|
|
NotProcessed |
Mmp8tm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - BN
|
HOM
|
2f:5m
|
|
|
NotProcessed |
Mmp8tm1.1(KOMP)Vlcg
|
JAX
|
Open Field - centre start / Distance travelled
|
HOM
|
32f:36m
|
|
|
NotProcessed |
Mmp8tm1.1(KOMP)Vlcg
|
JAX
|
Combined SHIRPA and Dysmorphology / Vocalization
|
HOM
|
7f:9m
|
Fisher Exact Test framework
|
0.619
|
Successful |
Mmp8tm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP3_S
|
HOM
|
2f:5m
|
|
|
NotProcessed |
Mmp8tm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP3_S
|
HOM
|
6f:4m
|
|
|
NotProcessed |
Mmp8tm1.1(KOMP)Vlcg
|
JAX
|
Combined SHIRPA and Dysmorphology / Touch escape
|
HOM
|
7f:9m
|
|
|
NotProcessed |
Mmp8tm1.1(KOMP)Vlcg
|
JAX
|
Tail Suspension / Time immobile
|
HOM
|
8f:9m
|
Linear Mixed Model framework, LME, including Weight
|
0.853
|
Successful |
Mmp8tm1.1(KOMP)Vlcg
|
JAX
|
Sleep Wake / Sleep daily percent
|
HOM
|
8f:6m
|
Linear Mixed Model framework, LME, not including Weight
|
0.152
|
Successful |
Mmp8tm1.1(KOMP)Vlcg
|
JAX
|
Light-Dark Test / Dark side time spent
|
HOM
|
8f:9m
|
Linear Mixed Model framework, LME, not including Weight
|
0.843
|
Successful |
Mmp8tm1.1(KOMP)Vlcg
|
JAX
|
Grip Strength / Forelimb and hindlimb grip strength measurement mean
|
HOM
|
8f:9m
|
Linear Mixed Model framework, LME, including Weight
|
0.232
|
Successful |
Mmp8tm1.1(KOMP)Vlcg
|
JAX
|
Sleep Wake / Sleep light phase percent
|
HOM
|
8f:6m
|
Linear Mixed Model framework, LME, including Weight
|
0.653
|
Successful |
Mmp8tm1.1(KOMP)Vlcg
|
JAX
|
Open Field - centre start / Number of rears - total
|
HOM
|
8f:9m
|
Linear Mixed Model framework, LME, including Weight
|
0.333
|
Successful |
Mmp8tm1.1(KOMP)Vlcg
|
JAX
|
Grip Strength / Forelimb grip strength measurement
|
HOM
|
24f:27m
|
|
|
NotProcessed |
Mmp8tm1.1(KOMP)Vlcg
|
JAX
|
Rotarod / Latency to fall
|
HOM
|
30f:35m
|
|
|
NotProcessed |
Mmp8tm1.1(KOMP)Vlcg
|
JAX
|
Tail Suspension / Latency to immobility
|
HOM
|
8f:9m
|
Linear Mixed Model framework, LME, including Weight
|
0.471
|
Successful |
Mmp8tm1.1(KOMP)Vlcg
|
JAX
|
Sleep Wake / Peak wake with respect to dark onset median
|
HOM
|
8f:6m
|
Linear Model Using Generalized Least Squares framework, GLS, including Weight
|
0.949
|
Successful |
Mmp8tm1.1(KOMP)Vlcg
|
JAX
|
Grip Strength / Forelimb grip strength normalised against body weight
|
HOM
|
8f:9m
|
Linear Mixed Model framework, LME, not including Weight
|
0.849
|
Successful |
Mmp8tm1.1(KOMP)Vlcg
|
JAX
|
Combined SHIRPA and Dysmorphology / Locomotor activity
|
HOM
|
7f:9m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0521
|
Successful |
Mmp8tm1.1(KOMP)Vlcg
|
JAX
|
Eye Morphology / Optic Disc
|
HOM
|
8f:9m
|
Fisher Exact Test framework
|
0.232
|
Successful |
Mmp8tm1.1(KOMP)Vlcg
|
JAX
|
Combined SHIRPA and Dysmorphology / Tail elevation
|
HOM
|
7f:9m
|
|
|
NotProcessed |
Mmp8tm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP2_S
|
HOM
|
2f:5m
|
|
|
NotProcessed |
Mmp8tm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP2_S
|
HOM
|
6f:4m
|
|
|
NotProcessed |
Mmp8tm1.1(KOMP)Vlcg
|
JAX
|
Open Field - centre start / Periphery average speed
|
HOM
|
8f:9m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0323
|
Successful |
Mmp8tm1.1(KOMP)Vlcg
|
JAX
|
Light-Dark Test / Time mobile dark side
|
HOM
|
8f:9m
|
Linear Mixed Model framework, LME, including Weight
|
0.537
|
Successful |
Mmp8tm1.1(KOMP)Vlcg
|
JAX
|
Light-Dark Test / Fecal boli
|
HOM
|
8f:9m
|
Linear Mixed Model framework, LME, including Weight
|
0.372
|
Successful |
Mmp8tm1.1(KOMP)Vlcg
|
JAX
|
Combined SHIRPA and Dysmorphology / Contact righting
|
HOM
|
7f:9m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Mmp8tm1.1(KOMP)Vlcg
|
JAX
|
Sleep Wake / Sleep dark phase percent
|
HOM
|
8f:6m
|
Linear Mixed Model framework, LME, including Weight
|
0.317
|
Successful |
Mmp8tm1.1(KOMP)Vlcg
|
JAX
|
Grip Strength / Forelimb and hindlimb grip strength normalised against body weight
|
HOM
|
8f:9m
|
Linear Mixed Model framework, LME, not including Weight
|
0.443
|
Successful |
Mmp8tm1.1(KOMP)Vlcg
|
JAX
|
Grip Strength / Forelimb and hindlimb grip strength measurement
|
HOM
|
24f:27m
|
|
|
NotProcessed |
Mmp8tm1.1(KOMP)Vlcg
|
JAX
|
Open Field - centre start / Distance travelled - total
|
HOM
|
8f:9m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0465
|
Successful |
Mmp8tm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP1_S
|
HOM
|
2f:5m
|
|
|
NotProcessed |
Mmp8tm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP1_S
|
HOM
|
6f:4m
|
|
|
NotProcessed |
Mmp8tm1.1(KOMP)Vlcg
|
JAX
|
Open Field - centre start / Periphery permanence time
|
HOM
|
8f:9m
|
Linear Mixed Model framework, LME, not including Weight
|
0.216
|
Successful |
Mmp8tm1.1(KOMP)Vlcg
|
JAX
|
Sleep Wake / Breath rate during sleep mean
|
HOM
|
8f:6m
|
Linear Mixed Model framework, LME, including Weight
|
0.239
|
Successful |
Mmp8tm1.1(KOMP)Vlcg
|
JAX
|
Combined SHIRPA and Dysmorphology / Gait
|
HOM
|
7f:9m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Mmp8tm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI1
|
HOM
|
6f:4m
|
Linear Mixed Model framework, LME, not including Weight
|
0.160
|
Successful |
Mmp8tm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI1
|
HOM
|
2f:5m
|
Linear Mixed Model framework, LME, not including Weight
|
0.399
|
Successful |
Mmp8tm1.1(KOMP)Vlcg
|
JAX
|
Rotarod / Learning slope
|
HOM
|
6f:7m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.755
|
Successful |
Mmp8tm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP4
|
HOM
|
6f:4m
|
|
|
NotProcessed |
Mmp8tm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP4
|
HOM
|
2f:5m
|
|
|
NotProcessed |
Mmp8tm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI3
|
HOM
|
6f:4m
|
Linear Mixed Model framework, LME, including Weight
|
0.118
|
Successful |
Mmp8tm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI3
|
HOM
|
2f:5m
|
Linear Mixed Model framework, LME, not including Weight
|
0.227
|
Successful |
Mmp8tm1.1(KOMP)Vlcg
|
JAX
|
Sleep Wake / Sleep bout lengths mean
|
HOM
|
8f:6m
|
Linear Mixed Model framework, LME, including Weight
|
0.875
|
Successful |
Mmp8tm1.1(KOMP)Vlcg
|
JAX
|
Combined SHIRPA and Dysmorphology / Tremor
|
HOM
|
7f:9m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Mmp8tm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI2
|
HOM
|
6f:4m
|
Linear Mixed Model framework, LME, including Weight
|
0.0170
|
Successful |
Mmp8tm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI2
|
HOM
|
2f:5m
|
Linear Mixed Model framework, LME, not including Weight
|
0.459
|
Successful |
Mmp8tm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - S
|
HOM
|
6f:4m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0839
|
Successful |
Mmp8tm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - S
|
HOM
|
2f:5m
|
Linear Model Using Generalized Least Squares framework, GLS, including Weight
|
0.719
|
Successful |
Mmp8tm1.1(KOMP)Vlcg
|
JAX
|
Light-Dark Test / Latency to first transition into dark
|
HOM
|
8f:9m
|
Linear Mixed Model framework, LME, not including Weight
|
0.295
|
Successful |
Mmp8tm1.1(KOMP)Vlcg
|
JAX
|
Rotarod / Learning difference
|
HOM
|
6f:7m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.721
|
Successful |
Mmp8tm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI4
|
HOM
|
6f:4m
|
Linear Mixed Model framework, LME, including Weight
|
0.0382
|
Successful |
Mmp8tm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI4
|
HOM
|
2f:5m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.0424
|
Successful |
Mmp8tm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP3
|
HOM
|
6f:4m
|
|
|
NotProcessed |
Mmp8tm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP3
|
HOM
|
2f:5m
|
|
|
NotProcessed |
Mmp8tm1.1(KOMP)Vlcg
|
JAX
|
Eye Morphology / Pupil Light Response
|
HOM
|
8f:9m
|
Fisher Exact Test framework
|
0.204
|
Successful |
Mmp8tm1.1(KOMP)Vlcg
|
JAX
|
Sleep Wake / Dark sleep bout lengths standard deviation
|
HOM
|
8f:6m
|
Linear Mixed Model framework, LME, not including Weight
|
0.522
|
Successful |
Mmp8tm1.1(KOMP)Vlcg
|
JAX
|
Combined SHIRPA and Dysmorphology / Limb grasp
|
HOM
|
7f:9m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Mmp8tm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP4_S
|
HOM
|
2f:5m
|
|
|
NotProcessed |
Mmp8tm1.1(KOMP)Vlcg
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP4_S
|
HOM
|
6f:4m
|
|
|
NotProcessed |
Mmp8tm1.1(KOMP)Vlcg
|
JAX
|
Sleep Wake / Light sleep bout lengths mean
|
HOM
|
8f:6m
|
Linear Mixed Model framework, LME, not including Weight
|
0.283
|
Successful |
Mmp8tm1.1(KOMP)Vlcg
|
JAX
|
Combined SHIRPA and Dysmorphology / Transfer arousal
|
HOM
|
7f:9m
|
|
|
NotProcessed |
Mmp8tm1.1(KOMP)Vlcg
|
JAX
|
Sleep Wake / Sleep bout lengths standard deviation
|
HOM
|
8f:6m
|
Linear Mixed Model framework, LME, including Weight
|
0.402
|
Successful |
Mmp8tm1.1(KOMP)Vlcg
|
JAX
|
Light-Dark Test / Percent time in dark
|
HOM
|
8f:9m
|
Linear Mixed Model framework, LME, including Weight
|
0.439
|
Successful |
Mmp8tm1.1(KOMP)Vlcg
|
JAX
|
Rotarod / Average duration
|
HOM
|
6f:7m
|
Linear Mixed Model framework, LME, including Weight
|
0.0216
|
Successful |
Mmp8tm1.1(KOMP)Vlcg
|
JAX
|
Open Field - centre start / Center distance travelled
|
HOM
|
8f:9m
|
Linear Mixed Model framework, LME, not including Weight
|
0.387
|
Successful |